Guide to the Human Genome
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Search of human proteins with 27734883

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27734883 tripartite motif family-like 2 [Homo sapiens]
         (387 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27734883 tripartite motif family-like 2 [Homo sapiens]             769   0.0  
gi|31542779 tripartite motif family-like 1 [Homo sapiens]             253   2e-67
gi|15208660 tripartite motif protein 21 [Homo sapiens]                191   7e-49
gi|112421127 tripartite motif-containing 58 [Homo sapiens]            161   1e-39
gi|21630277 tripartite motif-containing 11 [Homo sapiens]             152   4e-37
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]   143   2e-34
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]   137   2e-32
gi|5730009 ret finger protein [Homo sapiens]                          135   6e-32
gi|209862805 SPRY domain containing 5 [Homo sapiens]                  127   2e-29
gi|4557743 Mediterranean fever protein [Homo sapiens]                 125   5e-29
gi|169202375 PREDICTED: tripartite motif-containing protein 64B-...   124   1e-28
gi|210147600 tripartite motif-containing 64 [Homo sapiens]            124   2e-28
gi|63054855 erythroblast membrane-associated protein precursor [...   124   2e-28
gi|19923536 erythroblast membrane-associated protein precursor [...   124   2e-28
gi|5454014 tripartite motif-containing 38 [Homo sapiens]              123   3e-28
gi|37622899 ring finger protein 137 [Homo sapiens]                    119   6e-27
gi|89034201 PREDICTED: similar to ring finger protein 18 [Homo s...   118   8e-27
gi|9966829 ring finger protein 18 [Homo sapiens]                      117   2e-26
gi|169202726 PREDICTED: similar to ring finger protein 18 isofor...   114   1e-25
gi|169203362 PREDICTED: similar to ring finger protein 18 [Homo ...   114   1e-25
gi|239755484 PREDICTED: tripartite motif-containing protein 64C-...   114   1e-25
gi|239750042 PREDICTED: tripartite motif-containing protein 64C-...   114   1e-25
gi|239744353 PREDICTED: tripartite motif-containing protein 64C-...   114   1e-25
gi|27484954 PREDICTED: similar to ring finger protein 18 [Homo s...   114   1e-25
gi|157743261 tripartite motif-containing 75 [Homo sapiens]            114   1e-25
gi|239755486 PREDICTED: tripartite motif-containing protein 64C-...   114   2e-25
gi|239750044 PREDICTED: tripartite motif-containing protein 64C-...   114   2e-25
gi|89034675 PREDICTED: similar to hCG1802386 [Homo sapiens]           114   2e-25
gi|239744355 PREDICTED: tripartite motif-containing protein 64C-...   114   2e-25
gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens]      113   3e-25

>gi|27734883 tripartite motif family-like 2 [Homo sapiens]
          Length = 387

 Score =  770 bits (1987), Expect = 0.0
 Identities = 387/387 (100%), Positives = 387/387 (100%)

Query: 1   MVCGIQEAAENYRKLFQEILNTSREKLEAAKSILTDEQERMAMIQEEEQNFKKMIESEYS 60
           MVCGIQEAAENYRKLFQEILNTSREKLEAAKSILTDEQERMAMIQEEEQNFKKMIESEYS
Sbjct: 1   MVCGIQEAAENYRKLFQEILNTSREKLEAAKSILTDEQERMAMIQEEEQNFKKMIESEYS 60

Query: 61  MRLRLLNEECEQNLQRQQECISDLNLRETLLNQAIKLATELEEMFQEMLQRLGRVGRENM 120
           MRLRLLNEECEQNLQRQQECISDLNLRETLLNQAIKLATELEEMFQEMLQRLGRVGRENM
Sbjct: 61  MRLRLLNEECEQNLQRQQECISDLNLRETLLNQAIKLATELEEMFQEMLQRLGRVGRENM 120

Query: 121 EKLKESEARASEQVRSLLKLIVELEKKCGEGTLALLKNAKYSLERSKSLLLEHLEPAHIT 180
           EKLKESEARASEQVRSLLKLIVELEKKCGEGTLALLKNAKYSLERSKSLLLEHLEPAHIT
Sbjct: 121 EKLKESEARASEQVRSLLKLIVELEKKCGEGTLALLKNAKYSLERSKSLLLEHLEPAHIT 180

Query: 181 DLSLCHIRGLSSMFRVLQRHLTLDPETAHPCLALSEDLRTMRLRHGQQDGAGNPERLDFS 240
           DLSLCHIRGLSSMFRVLQRHLTLDPETAHPCLALSEDLRTMRLRHGQQDGAGNPERLDFS
Sbjct: 181 DLSLCHIRGLSSMFRVLQRHLTLDPETAHPCLALSEDLRTMRLRHGQQDGAGNPERLDFS 240

Query: 241 AMVLAAESFTSGRHYWEVDVEKATRWQVGIYHGSADAKGSTARASGEKVLLTGSVMGTEW 300
           AMVLAAESFTSGRHYWEVDVEKATRWQVGIYHGSADAKGSTARASGEKVLLTGSVMGTEW
Sbjct: 241 AMVLAAESFTSGRHYWEVDVEKATRWQVGIYHGSADAKGSTARASGEKVLLTGSVMGTEW 300

Query: 301 TLWVFPPLKRLFLEKKLDTVGVFLDCEHGQISFYNVTEMSLIYNFSHCAFQGALRPVFSL 360
           TLWVFPPLKRLFLEKKLDTVGVFLDCEHGQISFYNVTEMSLIYNFSHCAFQGALRPVFSL
Sbjct: 301 TLWVFPPLKRLFLEKKLDTVGVFLDCEHGQISFYNVTEMSLIYNFSHCAFQGALRPVFSL 360

Query: 361 CIPNGDTSPDSLTILQHGPSCDATVSP 387
           CIPNGDTSPDSLTILQHGPSCDATVSP
Sbjct: 361 CIPNGDTSPDSLTILQHGPSCDATVSP 387


>gi|31542779 tripartite motif family-like 1 [Homo sapiens]
          Length = 468

 Score =  253 bits (647), Expect = 2e-67
 Identities = 148/368 (40%), Positives = 210/368 (57%), Gaps = 36/368 (9%)

Query: 7   EAAENYRKLFQEILNTSREKLEAAKSILTDEQERMAMIQEEEQNFKKMIESEYSMRLRLL 66
           EA E++R+  QEILN  R + + A+++LT E+ER+ + QEE +  K+++ SEY    + L
Sbjct: 130 EAEEHHREKLQEILNLLRVRRKEAQAVLTHEKERVKLCQEETKTCKQVVVSEYMKMHQFL 189

Query: 67  NEECEQNLQRQQECISDLNLRETLLNQAIKLATELEEMFQEMLQRLGRVGRENMEKLKES 126
            EE  + LQ                                 LQ L +  +ENM KL+ +
Sbjct: 190 KEE--EQLQ---------------------------------LQLLEQEEKENMRKLRNN 214

Query: 127 EARASEQVRSLLKLIVELEKKCGEGTLALLKNAKYSLERSKSLLLEHLEPAHITDLSLCH 186
           E + ++Q+RSL K+I ++E          L+  + +LERS+ LLL+  E A  T+LSLC 
Sbjct: 215 EIKLTQQIRSLSKMIAQIESSSQSSAFESLEEVRGALERSEPLLLQCPE-ATTTELSLCR 273

Query: 187 IRGLSSMFRVLQRHLTLDPETAHPCLALSEDLRTMRLRHGQQDGAGNPERLDFSAMVLAA 246
           I G+  M R     +TLDP TA+  L LSEDL++++    +Q    NPER D SA VL  
Sbjct: 274 ITGMKEMLRKFSTEITLDPATANAYLVLSEDLKSVKYGGSRQQLPDNPERFDQSATVLGT 333

Query: 247 ESFTSGRHYWEVDVEKATRWQVGIYHGSADAKGSTARASGEKVLLTGSVMGTEWTLWVFP 306
           + FTSGRHYWEV+V   T W+VGI   S   KG+  +  G+   L G  +G +++LWV  
Sbjct: 334 QIFTSGRHYWEVEVGNKTEWEVGICKDSVSRKGNLPKPPGDLFSLIGLKIGDDYSLWVSS 393

Query: 307 PLKRLFLEKKLDTVGVFLDCEHGQISFYNVTEMSLIYNFSHCAFQGALRPVFSLCIPNGD 366
           PLK   + + +  VGVFLD E G I+FYN T+ SLIY+F   +FQ ALRP+FS C+PN  
Sbjct: 394 PLKGQHVREPVCKVGVFLDYESGHIAFYNGTDESLIYSFPQASFQEALRPIFSPCLPNEG 453

Query: 367 TSPDSLTI 374
           T+ D LTI
Sbjct: 454 TNTDPLTI 461


>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score =  191 bits (486), Expect = 7e-49
 Identities = 134/380 (35%), Positives = 189/380 (49%), Gaps = 55/380 (14%)

Query: 5   IQEAAENYRKLFQEILNTSREKLEAAKSILTDEQERMAMIQEEEQNFKKMIESEYSMRLR 64
           ++EAA+ Y++  Q  L   R K E A+ +  +   + A  ++  +  K  I +E+  +  
Sbjct: 128 LEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKN 187

Query: 65  LLNEECEQNLQRQQECISDLNLRETLLNQAIKLATELEEMFQEMLQRLGRVGRENMEKLK 124
            L EE ++ LQ                        ELE+  +E L+ LG           
Sbjct: 188 FLVEEEQRQLQ------------------------ELEKDEREQLRILG----------- 212

Query: 125 ESEARASEQVRSLLKLIVELEKKCGEGTLALLKNAKYSLERSKSLLLEHLEPAHITDLSL 184
           E EA+ ++Q ++L +LI EL+++C    L LL+     LERS+S  L+ L+       S+
Sbjct: 213 EKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSV 272

Query: 185 CHIRGLSSMFRVLQRHLTLDPETAHPCLALSEDLRTMRLRHGQQDGAGNPERLDFSAMVL 244
           CH+ GL  M R    H+TLDP+TA+P L LSED R +RL   QQ   GN ER D   MVL
Sbjct: 273 CHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVL 332

Query: 245 AAESFTSGRHYWEVDVEKATRWQVGIYHGSADAKGSTARASGEKVLLTGSVMGTEWTLWV 304
            A+ F SG+HYWEVDV     W +G+   S   KG           L  S  G  WT+W+
Sbjct: 333 GAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGH---------FLLSSKSGF-WTIWL 382

Query: 305 FP---------PLKRLFLEKKLDTVGVFLDCEHGQISFYNVTEM-SLIYNFSHCAFQGAL 354
           +          P   L L+     VG+FLD E G +SFYN+T+  SLIY+FS CAF G L
Sbjct: 383 WNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPL 442

Query: 355 RPVFSLCIPNGDTSPDSLTI 374
           RP FS    +G  +   LT+
Sbjct: 443 RPFFSPGFNDGGKNTAPLTL 462


>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
          Length = 486

 Score =  161 bits (407), Expect = 1e-39
 Identities = 116/357 (32%), Positives = 177/357 (49%), Gaps = 37/357 (10%)

Query: 5   IQEAAENYRKLFQEILNTSREKLEAAKSILTDEQERMAMIQEEEQNFKKMIESEYSMRLR 64
           +QEAA +Y+   Q  L   R++LE A   LT E    A + ++   +K+ +E +   R R
Sbjct: 132 LQEAAGSYQVKLQMALELMRKELEDA---LTQE----ANVGKKTVIWKEKVEMQ-RQRFR 183

Query: 65  LLNEECEQNLQRQQECISDLNLRETLLNQAIKLATELEEMFQEMLQRLGRVGRENMEKLK 124
           L  E+    L +++                           Q  L+RL    R  +++L+
Sbjct: 184 LEFEKHRGFLAQEE---------------------------QRQLRRLEAEERATLQRLR 216

Query: 125 ESEARASEQVRSLLKLIVELEKKCGEGTLALLKNAKYSLERSKSLLLEHLEPAHITDLSL 184
           ES++R  +Q ++L +L  EL+++C    L LL+  +  L RSK++     E   +   + 
Sbjct: 217 ESKSRLVQQSKALKELADELQERCQRPALGLLEGVRGVLSRSKAVTRLEAENIPMELKTA 276

Query: 185 CHIRGLSSMFRVLQRHLTLDPETAHPCLALSEDLRTMRLRHGQQDGAGNPERLDFSAMVL 244
           C I G   + R  Q  + LDP TAHP L L+ DLR+++     +D   NPER D    +L
Sbjct: 277 CCIPGRRELLRKFQVDVKLDPATAHPSLLLTADLRSVQDGEPWRDVPNNPERFDTWPCIL 336

Query: 245 AAESFTSGRHYWEVDVEKATRWQVGIYHGSADAKGSTARASGEKVLLTGSVMGTEWTLWV 304
             +SF+SGRHYWEV V +   W +G+   +   KG T  +    V     + G E+ +  
Sbjct: 337 GLQSFSSGRHYWEVLVGEGAEWGLGVCQDTLPRKGETTPSPENGVWALWLLKGNEYMVLA 396

Query: 305 FPPLKRLFLEKKLDTVGVFLDCEHGQISFYNVTEMSLIYNFSHCAFQGALRPVFSLC 361
            P +  L LE     +G+FLD E G+ISFYNVT+ S IY F+   F G LRP F +C
Sbjct: 397 SPSVPLLQLESP-RCIGIFLDYEAGEISFYNVTDGSYIYTFNQ-LFSGLLRPYFFIC 451


>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score =  152 bits (385), Expect = 4e-37
 Identities = 110/355 (30%), Positives = 176/355 (49%), Gaps = 18/355 (5%)

Query: 40  RMAMIQEEEQNFKKMIESEYSMRLRLLNEECEQNLQRQQECISDLNL----RETLLNQAI 95
           R+  +Q+  ++ K  +E       + + +      Q  + C+    +    R+ +L +  
Sbjct: 124 RVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNVLGEFE 183

Query: 96  KLATELEEMFQEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEGTLAL 155
           +L   L E  Q++LQRL     E + +L+E  A   +Q   L +LI ELE +C    L L
Sbjct: 184 RLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQLPALGL 243

Query: 156 LKNAKYSLERSKSLLLEHLEPAHITDLSLCHIRGLSSMFRVLQRHLTLDPETAHPCLALS 215
           L++ K +L R + + L+  E   +   ++C + GL    R  +  +TLDP+TA+P L LS
Sbjct: 244 LQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRGDVTLDPDTANPELILS 303

Query: 216 EDLRTMRLRHGQQDGAGNPERLDFSAMVLAAESFTSGRHYWEVDVEKATRWQVGIYHGSA 275
           ED R+++    +Q    +PER D    VL  E FTSGRHYWEV+V   T W +G+   + 
Sbjct: 304 EDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVGDRTSWALGVCRENV 363

Query: 276 D--AKGSTARASGEKVLL-TGSVMGTEWTLWVFPPLKRLFLEKKLDTVGVFLDCEHGQIS 332
           +   KG  +  +G  +L+  GS   +        PL+          VG+FLD E G +S
Sbjct: 364 NRKEKGELSAGNGFWILVFLGSYYNSSER--ALAPLR-----DPPRRVGIFLDYEAGHLS 416

Query: 333 FYNVTEMSLIYNFSHCAFQGALRPVFSLCIPNGDTSPDSLTILQHGPSCDATVSP 387
           FY+ T+ SL++ F    F G LRP+FS       +SP  +TI +       T++P
Sbjct: 417 FYSATDGSLLFIFPEIPFSGTLRPLFSPL----SSSPTPMTICRPKGGSGDTLAP 467


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score =  143 bits (361), Expect = 2e-34
 Identities = 109/340 (32%), Positives = 161/340 (47%), Gaps = 30/340 (8%)

Query: 58  EYSMRLRLLNEECEQNLQRQQECISDL------------NLRETLLNQAIKLATELEEMF 105
           EY  +L+   E  EQ LQ    C S              + R+ +L +  +L   L+E  
Sbjct: 149 EYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREFEELHRRLDEEQ 208

Query: 106 QEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEGTLALLKNAKYSLER 165
           Q +L RL    ++ +++L+E+ A   ++ R L  L  E+E KC +    +LK+ K +LE+
Sbjct: 209 QVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGFEMLKDVKSTLEK 268

Query: 166 SKSLLLEHLEPAHITDLSLCHIRGLSS----------MFRVLQRHLTLDPETAHPCLALS 215
                 E ++   +T +S+   +  S+          + + L   +TLDPETAHP L LS
Sbjct: 269 C-----EKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLIADVTLDPETAHPNLVLS 323

Query: 216 EDLRTMRLRHGQ-QDGAGNPERLDFSAMVLAAESFTSGRHYWEVDVEKATRWQVGIYHGS 274
           ED ++++    + +D    P R  F   VLA E FTSGRHYWEV+V   T W VG+   S
Sbjct: 324 EDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDS 383

Query: 275 ADAKGSTARASGEKVLLTGSVMGTEWTLWVFPPLKRLFLEKKLDTVGVFLDCEHGQISFY 334
              KG                 G ++      P   L ++ K   VG+FLD E G +SFY
Sbjct: 384 VSRKGELTPLPETGYWRVRLWNGDKYAA-TTTPFTPLHIKVKPKRVGIFLDYEAGTLSFY 442

Query: 335 NVTEMSLIYNFSHCAFQGALRPVFSLCIPNGDTSPDSLTI 374
           NVT+ S IY F+   F   L P+F   I  G  +   LTI
Sbjct: 443 NVTDRSHIYTFTD-TFTEKLWPLFYPGIRAGRKNAAPLTI 481


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score =  137 bits (345), Expect = 2e-32
 Identities = 112/365 (30%), Positives = 166/365 (45%), Gaps = 50/365 (13%)

Query: 58  EYSMRLRLLNEECEQNLQRQQECISDL------------NLRETLLNQAIKLATELEEMF 105
           EY  +L+   E  EQ LQ    C S              + R+ +L +  +L   L+E  
Sbjct: 149 EYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREFEELHRRLDEEQ 208

Query: 106 QEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEGTLALLKNAKYSLER 165
           Q +L RL    ++ +++L+E+ A   ++ R L  L  E+E KC +    +LK+ K +LE+
Sbjct: 209 QVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGFEMLKDVKSTLEK 268

Query: 166 S-----------------KSLL--------LEHLEPAHITDLSLCHIRGLSS-------- 192
           +                 K+LL         E ++   +T +S+   +  S+        
Sbjct: 269 NIPRKFGGSLSTICPRDHKALLGLVKEINRCEKVKTMEVTSVSIELEKNFSNFPRQYFAL 328

Query: 193 --MFRVLQRHLTLDPETAHPCLALSEDLRTMRLRHGQ-QDGAGNPERLDFSAMVLAAESF 249
             + + L   +TLDPETAHP L LSED ++++    + +D    P R  F   VLA E F
Sbjct: 329 RKILKQLIADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGF 388

Query: 250 TSGRHYWEVDVEKATRWQVGIYHGSADAKGSTARASGEKVLLTGSVMGTEWTLWVFPPLK 309
           TSGRHYWEV+V   T W VG+   S   KG                 G ++      P  
Sbjct: 389 TSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTPLPETGYWRVRLWNGDKYAA-TTTPFT 447

Query: 310 RLFLEKKLDTVGVFLDCEHGQISFYNVTEMSLIYNFSHCAFQGALRPVFSLCIPNGDTSP 369
            L ++ K   VG+FLD E G +SFYNVT+ S IY F+   F   L P+F   I  G  + 
Sbjct: 448 PLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFTD-TFTEKLWPLFYPGIRAGRKNA 506

Query: 370 DSLTI 374
             LTI
Sbjct: 507 APLTI 511


>gi|5730009 ret finger protein [Homo sapiens]
          Length = 513

 Score =  135 bits (340), Expect = 6e-32
 Identities = 104/355 (29%), Positives = 164/355 (46%), Gaps = 32/355 (9%)

Query: 44  IQEEEQNFKKMIESEYSMRLRLLNEECEQNLQRQQECISDLNL----RETLLNQAIKLAT 99
           ++E  + FK+ I+++     R+ + +  +  Q +Q     L+L    RE ++ +  +L  
Sbjct: 132 LEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFEQLYH 191

Query: 100 ELEEMFQEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEGTLALLKNA 159
            L+E    +L RL  +       +  +  + S  +  L  LI +LE+K  + T  LL++ 
Sbjct: 192 SLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTRELLQDI 251

Query: 160 KYSLERSKSLLLEH--------LEPAHI--------TDLSLCHIRGLSSMFRVLQR---- 199
             +L R++ + +           E  HI        T+        + S    +Q     
Sbjct: 252 GDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKIQELREA 311

Query: 200 -----HLTLDPETAHPCLALSEDLRTMRLRHGQQDGAGNPERLDFSAMVLAAESFTSGRH 254
                 +TLDP+TA+P L LS++LR +R  + QQD   NPER +    VL +  F +GRH
Sbjct: 312 QLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFIAGRH 371

Query: 255 YWEVDVEKATRWQVGIYHGSADAKGSTARASGEKVLLTGSVMGTE-WTLWVFPPLKRLFL 313
           YWEV+V    +W +G+   S   KG    A            G E W L    P+  L L
Sbjct: 372 YWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWAL--TSPMTALPL 429

Query: 314 EKKLDTVGVFLDCEHGQISFYNVTEMSLIYNFSHCAFQGALRPVFSLCIPNGDTS 368
              L  VG+FLD + G++SFYNVTE    + FSH  F G +RP FSL    G ++
Sbjct: 430 RTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSGGKSA 484


>gi|209862805 SPRY domain containing 5 [Homo sapiens]
          Length = 452

 Score =  127 bits (319), Expect = 2e-29
 Identities = 101/326 (30%), Positives = 163/326 (50%), Gaps = 16/326 (4%)

Query: 37  EQERMAMIQEEEQNFKKMIESEYSMRLRLLNEECEQNLQRQQECISD-LNLR-ETLLNQA 94
           E+ R  ++++ +  ++K  E+     LR LN E  +       C  D ++LR E +  + 
Sbjct: 134 EERREELLKKMQSLWEKACEN-----LRNLNMETTRT-----RCWKDYVSLRIEAIRAEY 183

Query: 95  IKLATELEEMFQEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEGTLA 154
            K+   L E  Q  L+RL + G +  ++L ES+AR       L  +  +L++ C +  + 
Sbjct: 184 QKMPAFLHEEEQHHLERLRKEGEDIFQQLNESKARMEHSRELLRGMYEDLKQMCHKADVE 243

Query: 155 LLKNAKYSLERSKSLLLEHLEPAHITDLSLCHIRGLSSMFRVLQRHLTLDPETAHPCLAL 214
           LL+     L R +SLLL+  EP +  +LS   I GL       +   TL PE A+  + L
Sbjct: 244 LLQAFGDILHRYESLLLQVSEPVN-PELSAGPITGLLDSLSGFRVDFTLQPERANSHIFL 302

Query: 215 SEDLRTMRLRHGQQDGAGNPERLDFSAMVLAAESFTSGRHYWEVDVEKATRWQVGIYHGS 274
             DLR+M +    QD      + +   +V  A++FTSG++YWEV +  +  W  G+ +  
Sbjct: 303 CGDLRSMNVGCDPQDDPDITGKSE-CFLVWGAQAFTSGKYYWEVHMGDSWNWAFGVCNNY 361

Query: 275 ADAKGSTARASGEKVL-LTGSVM-GTEWTLWVFPPLKRLFLEKKLDTVGVFLDCEHGQIS 332
              K    +  GE+ L L G V   T  +L+   PL   ++ +   TVG+FLDCE   +S
Sbjct: 362 WKEKRQNDKIDGEEGLFLLGCVKEDTHCSLFTTSPLVVQYVPRPTSTVGLFLDCEGRTVS 421

Query: 333 FYNVTEMSLIYNFSHCAFQGALRPVF 358
           F +V + SLIY   +C+F   LRP+F
Sbjct: 422 FVDVDQSSLIYTIPNCSFSPPLRPIF 447



 Score = 30.0 bits (66), Expect = 3.7
 Identities = 28/109 (25%), Positives = 49/109 (44%), Gaps = 6/109 (5%)

Query: 6   QEAAENYRKLFQEILNTSREKLEAA---KSILTDEQERMAMIQEEEQNFKKMIESEYSMR 62
           ++A EN R L  E   T   K   +   ++I  + Q+  A + EEEQ+  + +  E    
Sbjct: 149 EKACENLRNLNMETTRTRCWKDYVSLRIEAIRAEYQKMPAFLHEEEQHHLERLRKEGEDI 208

Query: 63  LRLLNEECEQNLQRQQECISDLNLRETLLNQAIKLATELEEMFQEMLQR 111
            + LNE  +  ++  +E +    + E L     K   EL + F ++L R
Sbjct: 209 FQQLNES-KARMEHSRELLR--GMYEDLKQMCHKADVELLQAFGDILHR 254


>gi|4557743 Mediterranean fever protein [Homo sapiens]
          Length = 781

 Score =  125 bits (315), Expect = 5e-29
 Identities = 112/374 (29%), Positives = 167/374 (44%), Gaps = 40/374 (10%)

Query: 40  RMAMIQEEEQNFKKMIESEYSMRLRLLNEECEQNLQRQQECISDLNLRETL-------LN 92
           R+  I+E     KK I+ +     +L     EQ    +++ +S L   E L       L 
Sbjct: 408 RVRPIEEVALEHKKKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLE 467

Query: 93  QAIKLATELEEMFQEMLQRLGR-VGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEG 151
           Q      + E  F   L+ +G+ VG+      K  + R S+ +  L  LI ELE K  + 
Sbjct: 468 QVYYFLEQQEHFFVASLEDVGQMVGQIR----KAYDTRVSQDIALLDALIGELEAKECQS 523

Query: 152 TLALLKNAKYSLERSKSLLLEH--LEPAHITD-LSLCH----------------IRGLSS 192
              LL++    L R+K++ +      P  I   + L H                +R    
Sbjct: 524 EWELLQDIGDILHRAKTVPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEME 583

Query: 193 MFRV-----LQRH---LTLDPETAHPCLALSEDLRTMRLRHGQQDGAGNPERLDFSAMVL 244
           MF V      Q H   + LD ETA+P L  S+DL+++RL +  +     P+R D   +VL
Sbjct: 584 MFNVPELIGAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVL 643

Query: 245 AAESFTSGRHYWEVDVEKATRWQVGIYHGSADAKGSTARASGEKVLLTGSVMGTEWTLWV 304
            + SF SGR YWEV+V   T W +G    S   KG+   +      +   +   E+    
Sbjct: 644 GSPSFLSGRRYWEVEVGDKTAWILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQASS 703

Query: 305 FPPLKRLFLEKKLDTVGVFLDCEHGQISFYNVTEMSLIYNFSHCAFQGALRPVFSLCIPN 364
            PP  RL +++    VG+F+D   G ISFYNVT  S IY F+ C+F G L+P+FS    +
Sbjct: 704 VPP-TRLLIKEPPKRVGIFVDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRD 762

Query: 365 GDTSPDSLTILQHG 378
           G  +   LTI   G
Sbjct: 763 GGKNTAPLTICPVG 776


>gi|169202375 PREDICTED: tripartite motif-containing protein
           64B-like [Homo sapiens]
          Length = 449

 Score =  124 bits (311), Expect = 1e-28
 Identities = 91/317 (28%), Positives = 156/317 (49%), Gaps = 10/317 (3%)

Query: 47  EEQNFKKMIESEYSMRLRLLNEECEQNLQRQQECISDL----NLRETLLN-QAIKLATEL 101
           EE   K + E +Y   L  +N+E   NL ++      L    ++R+ ++  Q  K+   L
Sbjct: 133 EECREKLIKEMDY---LWEINQETRNNLNQETSTFHSLKDYVSVRKRIITIQYQKMPIFL 189

Query: 102 EEMFQEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEGTLALLKNAKY 161
           +E  Q  LQ L R   E  ++L++S+ R ++ +  +  +  EL + C    + LL++ + 
Sbjct: 190 DEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWETCHMPDVVLLQDVRN 249

Query: 162 SLERSKSLLLEHLEPAHITDLSLCHIRGLSSMFRVLQRHLTLDPETAHPCLALSEDLRTM 221
              R+    ++  +P +    S C I G+  M    +    L  E     ++LSED+R +
Sbjct: 250 VSARTDLAQMQKPQPVNPELTSWC-ITGVLDMLNNFRVDSALSTEMIPCYISLSEDVRYV 308

Query: 222 RLRHGQQDGAGNPERLDFSAMVLAAESFTSGRHYWEVDVEKATRWQVGIYHGSADAKGST 281
                      +P+ +D S  V  A++FTSG+HYWEVDV  ++ W +G+   S  A  + 
Sbjct: 309 IFGDDHLSAPTDPQGVD-SFAVWGAQAFTSGKHYWEVDVTLSSNWILGVCRDSRTADANF 367

Query: 282 ARASGEKVLLTGSVMGTEWTLWVFPPLKRLFLEKKLDTVGVFLDCEHGQISFYNVTEMSL 341
              S E+  L  S     ++L    P    ++++ L  VGVFLD ++G +SF++V++ SL
Sbjct: 368 VIDSDERFFLISSKRSNHYSLSTNSPPLIQYVQRPLGRVGVFLDYDNGSVSFFDVSKGSL 427

Query: 342 IYNFSHCAFQGALRPVF 358
           IY F   +F   LRP F
Sbjct: 428 IYGFPPSSFSSPLRPFF 444


>gi|210147600 tripartite motif-containing 64 [Homo sapiens]
          Length = 449

 Score =  124 bits (310), Expect = 2e-28
 Identities = 91/317 (28%), Positives = 156/317 (49%), Gaps = 10/317 (3%)

Query: 47  EEQNFKKMIESEYSMRLRLLNEECEQNLQRQQECISDL----NLRETLLN-QAIKLATEL 101
           EE   K + E +Y   L  +N+E   NL ++      L    ++R+ ++  Q  K+   L
Sbjct: 133 EECREKLIKEMDY---LWEINQETRNNLNQETRTFHSLKDYVSVRKRIITIQYQKMPIFL 189

Query: 102 EEMFQEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEGTLALLKNAKY 161
           +E  Q  LQ L R   E  ++L++S+ R ++ +  +  +  EL + C    + LL++ + 
Sbjct: 190 DEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWETCHVPDVELLQDVRN 249

Query: 162 SLERSKSLLLEHLEPAHITDLSLCHIRGLSSMFRVLQRHLTLDPETAHPCLALSEDLRTM 221
              R+    ++  +P +    S C I G+  M    +    L  E     ++LSED+R +
Sbjct: 250 VSARTDLAQMQKPQPVNPELTSWC-ITGVLDMLNNFRVDSALSTEMIPCYISLSEDVRYV 308

Query: 222 RLRHGQQDGAGNPERLDFSAMVLAAESFTSGRHYWEVDVEKATRWQVGIYHGSADAKGST 281
                      +P+ +D S  V  A++FTSG+HYWEVDV  ++ W +G+   S  A  + 
Sbjct: 309 IFGDDHLSAPTDPQGVD-SFAVWGAQAFTSGKHYWEVDVTLSSNWILGVCQDSRTADANF 367

Query: 282 ARASGEKVLLTGSVMGTEWTLWVFPPLKRLFLEKKLDTVGVFLDCEHGQISFYNVTEMSL 341
              S E+  L  S     ++L    P    ++++ L  VGVFLD ++G +SF++V++ SL
Sbjct: 368 VIDSDERFFLISSKRSNHYSLSTNSPPLIQYVQRPLGQVGVFLDYDNGSVSFFDVSKGSL 427

Query: 342 IYNFSHCAFQGALRPVF 358
           IY F   +F   LRP F
Sbjct: 428 IYGFPPSSFSSPLRPFF 444


>gi|63054855 erythroblast membrane-associated protein precursor
           [Homo sapiens]
          Length = 475

 Score =  124 bits (310), Expect = 2e-28
 Identities = 73/187 (39%), Positives = 98/187 (52%), Gaps = 2/187 (1%)

Query: 201 LTLDPETAHPCLALSEDLRTMRLRHGQQDGAGNPERLDFSAMVLAAESFTSGRHYWEVDV 260
           +TLDP+TAHP L LSED R +RL   +Q    NP+R DF   +L +E FT+G HYWEV V
Sbjct: 240 VTLDPDTAHPKLILSEDQRCVRLGDRRQPVPDNPQRFDFVVSILGSEYFTTGCHYWEVYV 299

Query: 261 EKATRWQVGIYHGSADAKGSTARASGEKVLLTGSVMGTEWTLWVFPPLKRLFLEKKLDTV 320
              T+W +G+   S   KG    +      L     G E+   +  P     L++    V
Sbjct: 300 GDKTKWILGVCSESVSRKGKVTASPANGHWLLRQSRGNEYEA-LTSPQTSFRLKEPPRCV 358

Query: 321 GVFLDCEHGQISFYNVTEMSLIYNFSHCAFQGALRPVFSLCIPNGDTSPDSLTILQHGPS 380
           G+FLD E G ISFYNVT  S I+ F+H  F G LRP F  C+ +G  +   L I      
Sbjct: 359 GIFLDYEAGVISFYNVTNKSHIFTFTH-NFSGPLRPFFEPCLHDGGKNTAPLVICSELHK 417

Query: 381 CDATVSP 387
            + ++ P
Sbjct: 418 SEESIVP 424


>gi|19923536 erythroblast membrane-associated protein precursor
           [Homo sapiens]
          Length = 475

 Score =  124 bits (310), Expect = 2e-28
 Identities = 73/187 (39%), Positives = 98/187 (52%), Gaps = 2/187 (1%)

Query: 201 LTLDPETAHPCLALSEDLRTMRLRHGQQDGAGNPERLDFSAMVLAAESFTSGRHYWEVDV 260
           +TLDP+TAHP L LSED R +RL   +Q    NP+R DF   +L +E FT+G HYWEV V
Sbjct: 240 VTLDPDTAHPKLILSEDQRCVRLGDRRQPVPDNPQRFDFVVSILGSEYFTTGCHYWEVYV 299

Query: 261 EKATRWQVGIYHGSADAKGSTARASGEKVLLTGSVMGTEWTLWVFPPLKRLFLEKKLDTV 320
              T+W +G+   S   KG    +      L     G E+   +  P     L++    V
Sbjct: 300 GDKTKWILGVCSESVSRKGKVTASPANGHWLLRQSRGNEYEA-LTSPQTSFRLKEPPRCV 358

Query: 321 GVFLDCEHGQISFYNVTEMSLIYNFSHCAFQGALRPVFSLCIPNGDTSPDSLTILQHGPS 380
           G+FLD E G ISFYNVT  S I+ F+H  F G LRP F  C+ +G  +   L I      
Sbjct: 359 GIFLDYEAGVISFYNVTNKSHIFTFTH-NFSGPLRPFFEPCLHDGGKNTAPLVICSELHK 417

Query: 381 CDATVSP 387
            + ++ P
Sbjct: 418 SEESIVP 424


>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
          Length = 465

 Score =  123 bits (308), Expect = 3e-28
 Identities = 93/328 (28%), Positives = 157/328 (47%), Gaps = 11/328 (3%)

Query: 42  AMIQEEEQNFKKMIESEYSMRLRLLNEECEQNLQRQQECISDLNLRETLLNQAIK----- 96
           A++++  Q +K+ ++   + +L+ L + C +        I+    +  +  Q I+     
Sbjct: 127 ALVEDVCQGYKEKLQKAVT-KLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIRSDFKN 185

Query: 97  LATELEEMFQEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEGTLALL 156
           L   L E  +  L RL +  ++ + +L++ EA    +   L   I+ELE+KC      LL
Sbjct: 186 LQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGSAQKLL 245

Query: 157 KNAKYSLERSKSLLLEHLEPAHITDLSLCHIRGL----SSMFRVLQRHLTLDPETAHPCL 212
           +N   +L RS ++ LE  E   +   ++C++  L      M R  Q  +TLDP+TAH  L
Sbjct: 246 QNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLRSHQVSVTLDPDTAHHEL 305

Query: 213 ALSEDLRTMRLRHGQQDGAGNPERLDFSAMVLAAESFTSGRHYWEVDVEKATRWQVGIYH 272
            LSED R +   + Q++   +  R      VL  E FTSGR Y+EVDV + T W +G+  
Sbjct: 306 ILSEDRRQVTRGYTQENQDTSSRRFTAFPCVLGCEGFTSGRRYFEVDVGEGTGWDLGVCM 365

Query: 273 GSADAKGSTARASGEKVLLTGSVMGTEWTLWVFPPLKRLFLEKKLDTVGVFLDCEHGQIS 332
            +   +G+  +   +    T  +   +  + +  P   L L ++   VG+FLD E G +S
Sbjct: 366 ENVQ-RGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLHEQPLLVGIFLDYEAGVVS 424

Query: 333 FYNVTEMSLIYNFSHCAFQGALRPVFSL 360
           FYN      I+ F   +F   LRP F +
Sbjct: 425 FYNGNTGCHIFTFPKASFSDTLRPYFQV 452


>gi|37622899 ring finger protein 137 [Homo sapiens]
          Length = 485

 Score =  119 bits (297), Expect = 6e-27
 Identities = 101/376 (26%), Positives = 165/376 (43%), Gaps = 31/376 (8%)

Query: 2   VCGIQEAAENYRKLFQEILNTSREKLEAAKSILTDEQERMAMIQEEEQNFKKMIESEYSM 61
           V  +++ A  Y+    E L   +++ E A  +   E++R A  + + +  K+ I  E+  
Sbjct: 131 VVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTATWKIQVETRKQSIVWEFEK 190

Query: 62  RLRLLNEECEQNLQRQQECISDLNLRETLLNQAIKLATELEEMFQEMLQRLGRVGRENME 121
             RLL ++   + Q   E  +                          L  L R   E M+
Sbjct: 191 YQRLLEKKQPPHRQLGAEVAA-------------------------ALASLQREAAETMQ 225

Query: 122 KLKESEARASEQVRSLLKLIVELEKKCGEGTLALLKNAKYSLERSKSLLLEHLEPAHITD 181
           KL+ + +   +Q + L ++I EL+++       +L++ +  L RSKS  L+  EP  +  
Sbjct: 226 KLELNHSELIQQSQVLWRMIAELKERSQRPVRWMLQDIQEVLNRSKSWSLQQPEPISLEL 285

Query: 182 LSLCHIRGLSSMFRVLQRHLTLDPETAHPCLALSEDLRTMRLRHGQQDGAGNPERLDFSA 241
            + C + GL  + +     + LDP+TA+  L +SED + +      Q    NPER     
Sbjct: 286 KTDCRVLGLREILKTYAADVRLDPDTAYSRLIVSEDRKRVHYGDTNQKLPDNPERFYRYN 345

Query: 242 MVLAAESFTSGRHYWEVDVEKATRWQVGIYHGSADAKGSTARASGEKVLLTGSVMGTEWT 301
           +VL ++  +SGRHYWEV+V   + W +G+   + D K     +      +     G E+ 
Sbjct: 346 IVLGSQCISSGRHYWEVEVGDRSEWGLGVCKQNVDRKEVVYLSPHYGFWVIRLRKGNEYR 405

Query: 302 LWV--FPPLKRLFLEKKLDTVGVFLDCEHGQISFYNVTEM-SLIYNFSHCAFQGALRPVF 358
                +P L    L      VG+F+D E   ISFYNVT+  S I+ F    F G L P F
Sbjct: 406 AGTDEYPILS---LPVPPRRVGIFVDYEAHDISFYNVTDCGSHIFTFPRYPFPGRLLPYF 462

Query: 359 SLCIPNGDTSPDSLTI 374
           S C   G  +   L I
Sbjct: 463 SPCYSIGTNNTAPLAI 478


>gi|89034201 PREDICTED: similar to ring finger protein 18 [Homo
           sapiens]
          Length = 452

 Score =  118 bits (296), Expect = 8e-27
 Identities = 91/328 (27%), Positives = 157/328 (47%), Gaps = 20/328 (6%)

Query: 37  EQERMAMIQEEEQNFKKMIESEYSMRLRLLNEECEQNLQRQQECISDLNLR-ETLLNQAI 95
           E+ R  ++Q+ +  ++K  E+  ++ +      C ++          +NLR E +  +  
Sbjct: 134 EEHREKLLQKMQSLWEKACENHRNLNVETTRTRCWKDY---------VNLRLEAIRAEYQ 184

Query: 96  KLATELEEMFQEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEGTLAL 155
           K+     E  +  L+ L + G+E   +L  S+A+ + ++  L  +  EL + C +  + L
Sbjct: 185 KMPAFHHEEEKHNLEMLKKKGKEIFHRLHLSKAKMAHRMEILRGMYEELNEMCHKPDVEL 244

Query: 156 LKNAKYSLERSKSLLLEHLEPAHITDLSLCHIRGLSSMFRVLQRHLTLDPETAHPCLALS 215
           L+     L RS+S+LL   +P +  +LS   I GL       + H+TL  E A+  + L 
Sbjct: 245 LQAFGDILHRSESVLLHMPQPLN-PELSAGPITGLRDRLNQFRVHITLHHEEANSDIFLY 303

Query: 216 EDLRTMRLRHGQQDG---AGNPERLDFSAMVLAAESFTSGRHYWEVDVEKATRWQVGIYH 272
           E LR+M +    QD       P     S +    ++FTSG++YWEV V  +  W  G+ +
Sbjct: 304 EILRSMCIGCDHQDVPYFTATPR----SFLAWGVQTFTSGKYYWEVHVGDSWNWAFGVCN 359

Query: 273 GSADAKGSTARASG-EKVLLTGSVMGT-EWTLWVFPPLKRLFLEKKLDTVGVFLDCEHGQ 330
                K    +  G E + L G +    + +L+   PL   ++ K    VG+FLDCE   
Sbjct: 360 MYRKEKNQNEKIDGKEGLFLLGCIKNDIQCSLFTTSPLMLQYIPKPTSRVGLFLDCEAKT 419

Query: 331 ISFYNVTEMSLIYNFSHCAFQGALRPVF 358
           +SF +V + SLIY   +C+F   LRP+F
Sbjct: 420 VSFVDVNQSSLIYTIPNCSFSPPLRPIF 447


>gi|9966829 ring finger protein 18 [Homo sapiens]
          Length = 452

 Score =  117 bits (293), Expect = 2e-26
 Identities = 92/328 (28%), Positives = 157/328 (47%), Gaps = 20/328 (6%)

Query: 37  EQERMAMIQEEEQNFKKMIESEYSMRLRLLNEECEQNLQRQQECISDLNLR-ETLLNQAI 95
           E+ R  ++Q+ +  ++K  E+  ++ +      C ++          +NLR E +  +  
Sbjct: 134 EEHREKLLQKMQSLWEKACENHRNLNVETTRTRCWKDY---------VNLRLEAIRAEYQ 184

Query: 96  KLATELEEMFQEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEGTLAL 155
           K+     E  +  L+ L + G+E   +L  S+A+ + ++  L  +  EL + C +  + L
Sbjct: 185 KMPAFHHEEEKHNLEMLKKKGKEIFHRLHLSKAKMAHRMEILRGMYEELNEMCHKPDVEL 244

Query: 156 LKNAKYSLERSKSLLLEHLEPAHITDLSLCHIRGLSSMFRVLQRHLTLDPETAHPCLALS 215
           L+     L RS+S+LL   +P +  +LS   I GL       + H+TL  E A+  + L 
Sbjct: 245 LQAFGDILHRSESVLLHMPQPLN-PELSAGPITGLRDRLNQFRVHITLHHEEANNDIFLY 303

Query: 216 EDLRTMRLRHGQQDG---AGNPERLDFSAMVLAAESFTSGRHYWEVDVEKATRWQVGIYH 272
           E LR+M +    QD       P     S +    ++FTSG++YWEV V  +  W  G+ +
Sbjct: 304 EILRSMCIGCDHQDVPYFTATPR----SFLAWGVQTFTSGKYYWEVHVGDSWNWAFGVCN 359

Query: 273 GSADAKGSTARASGEKVL-LTGSVMGT-EWTLWVFPPLKRLFLEKKLDTVGVFLDCEHGQ 330
                K    +  G+  L L G V    + +L+   PL   ++ K    VG+FLDCE   
Sbjct: 360 MYRKEKNQNEKIDGKAGLFLLGCVKNDIQCSLFTTSPLMLQYIPKPTSRVGLFLDCEAKT 419

Query: 331 ISFYNVTEMSLIYNFSHCAFQGALRPVF 358
           +SF +V + SLIY   +C+F   LRP+F
Sbjct: 420 VSFVDVNQSSLIYTIPNCSFSPPLRPIF 447


>gi|169202726 PREDICTED: similar to ring finger protein 18 isoform 1
           [Homo sapiens]
          Length = 452

 Score =  114 bits (286), Expect = 1e-25
 Identities = 91/328 (27%), Positives = 157/328 (47%), Gaps = 20/328 (6%)

Query: 37  EQERMAMIQEEEQNFKKMIESEYSMRLRLLNEECEQNLQRQQECISDLNLR-ETLLNQAI 95
           E+ +  ++Q+ +  ++K  E+  ++ +      C ++          +NLR E +  +  
Sbjct: 134 EEHQEKLLQKMQSLWEKACENHRNLNVETTRTRCWKDY---------VNLRLEAIRAEYQ 184

Query: 96  KLATELEEMFQEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEGTLAL 155
           K+     E  +  L+ L + G++   +L  S+A+ + +   L  +  EL + C +  + L
Sbjct: 185 KMPAFHHEEEKHNLEMLKKKGKDIFHRLHLSKAKMAHRREILRGMYEELNEMCHKPDVEL 244

Query: 156 LKNAKYSLERSKSLLLEHLEPAHITDLSLCHIRGLSSMFRVLQRHLTLDPETAHPCLALS 215
           L+     L RS+S+LL   +P +  +LS   I GL       + H+TL  E A+  + L 
Sbjct: 245 LQAFGDILHRSESVLLHMPQPLN-PELSAGPITGLRDRLNQFRVHITLHHEEANSDIFLC 303

Query: 216 EDLRTMRLRHGQQDG---AGNPERLDFSAMVLAAESFTSGRHYWEVDVEKATRWQVGIYH 272
           E LR+M +    QD       P     S +   A++FTSG++YWEV V  +  W  G+ +
Sbjct: 304 EILRSMCIGCDHQDVPYFTATPR----SFLAWGAQTFTSGKYYWEVHVGDSWNWAFGVCN 359

Query: 273 GSADAKGSTARASGEKVL-LTGSVMGT-EWTLWVFPPLKRLFLEKKLDTVGVFLDCEHGQ 330
                K    +  GE  L L G V    + +L+   PL   ++ +    VG+FLDCE   
Sbjct: 360 MYWKEKNQNEKIDGEDGLFLLGCVKNDIQRSLFTTSPLMLQYIPRPTSRVGLFLDCEAKT 419

Query: 331 ISFYNVTEMSLIYNFSHCAFQGALRPVF 358
           +SF +V + SLIY   +C+F   LRP+F
Sbjct: 420 VSFVDVNQSSLIYTIPNCSFSPPLRPIF 447


>gi|169203362 PREDICTED: similar to ring finger protein 18 [Homo
           sapiens]
          Length = 452

 Score =  114 bits (286), Expect = 1e-25
 Identities = 91/328 (27%), Positives = 157/328 (47%), Gaps = 20/328 (6%)

Query: 37  EQERMAMIQEEEQNFKKMIESEYSMRLRLLNEECEQNLQRQQECISDLNLR-ETLLNQAI 95
           E+ +  ++Q+ +  ++K  E+  ++ +      C ++          +NLR E +  +  
Sbjct: 134 EEHQEKLLQKMQSLWEKACENHRNLNVETTRTRCWKDY---------VNLRLEAIRAEYQ 184

Query: 96  KLATELEEMFQEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEGTLAL 155
           K+     E  +  L+ L + G++   +L  S+A+ + +   L  +  EL + C +  + L
Sbjct: 185 KMPAFHHEEEKHNLEMLKKKGKDIFHRLHLSKAKMAHRREILRGMYEELNEMCHKPDVEL 244

Query: 156 LKNAKYSLERSKSLLLEHLEPAHITDLSLCHIRGLSSMFRVLQRHLTLDPETAHPCLALS 215
           L+     L RS+S+LL   +P +  +LS   I GL       + H+TL  E A+  + L 
Sbjct: 245 LQAFGDILHRSESVLLHMPQPLN-PELSAGPITGLRDRLNQFRVHITLHHEEANSDIFLC 303

Query: 216 EDLRTMRLRHGQQDG---AGNPERLDFSAMVLAAESFTSGRHYWEVDVEKATRWQVGIYH 272
           E LR+M +    QD       P     S +   A++FTSG++YWEV V  +  W  G+ +
Sbjct: 304 EILRSMCIGCDHQDVPYFTATPR----SFLAWGAQTFTSGKYYWEVHVGDSWNWAFGVCN 359

Query: 273 GSADAKGSTARASGEKVL-LTGSVMGT-EWTLWVFPPLKRLFLEKKLDTVGVFLDCEHGQ 330
                K    +  GE  L L G V    + +L+   PL   ++ +    VG+FLDCE   
Sbjct: 360 MYWKEKNQNEKIDGEDGLFLLGCVKNDIQRSLFTTSPLMLQYIPRPTSRVGLFLDCEAKT 419

Query: 331 ISFYNVTEMSLIYNFSHCAFQGALRPVF 358
           +SF +V + SLIY   +C+F   LRP+F
Sbjct: 420 VSFVDVNQSSLIYTIPNCSFSPPLRPIF 447


>gi|239755484 PREDICTED: tripartite motif-containing protein
           64C-like isoform 1 [Homo sapiens]
          Length = 450

 Score =  114 bits (285), Expect = 1e-25
 Identities = 88/318 (27%), Positives = 156/318 (49%), Gaps = 11/318 (3%)

Query: 47  EEQNFKKMI-ESEYSMRLRLLNEECEQNLQRQQECISDL----NLRETLLN-QAIKLATE 100
           EE   +K+I E +Y  ++   N+E + NL ++      L    +LR+ ++  Q  K+   
Sbjct: 133 EECRVQKLIKEMDYLWKI---NQETQNNLNQETSKFCSLVDYVSLRKVIITIQYQKMHIF 189

Query: 101 LEEMFQEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEGTLALLKNAK 160
           L+E  Q  LQ L R  +E  ++L++S+ R ++ +  +  +  EL +      + LL++  
Sbjct: 190 LDEEEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRELWETYHMPDVELLQDVG 249

Query: 161 YSLERSKSLLLEHLEPAHITDLSLCHIRGLSSMFRVLQRHLTLDPETAHPCLALSEDLRT 220
               R+    +   +P +    S C I G+  M    +    L  E     ++LSED+R 
Sbjct: 250 NISARTDLAQMPKPQPVNPELTSWC-ITGVLDMLNNFRVDNALSTEMTPCYISLSEDVRR 308

Query: 221 MRLRHGQQDGAGNPERLDFSAMVLAAESFTSGRHYWEVDVEKATRWQVGIYHGSADAKGS 280
           +      +    +P+ ++ S  V  A++FTSG+HYWEVDV  ++ W +G+   S  A  +
Sbjct: 309 VIFGDDHRSAPMDPQGVE-SFAVWCAQAFTSGKHYWEVDVTHSSNWILGVCRDSRTADTN 367

Query: 281 TARASGEKVLLTGSVMGTEWTLWVFPPLKRLFLEKKLDTVGVFLDCEHGQISFYNVTEMS 340
               S +      S     ++L    P    ++++ L  VGVFLD ++G +SF++V++ S
Sbjct: 368 IVIDSDKTFFSISSKTSNHYSLSTNSPPLIQYVQRPLGWVGVFLDYDNGSVSFFDVSKGS 427

Query: 341 LIYNFSHCAFQGALRPVF 358
           LIY F   +F   LRP F
Sbjct: 428 LIYGFPPSSFSSPLRPFF 445


>gi|239750042 PREDICTED: tripartite motif-containing protein
           64C-like isoform 1 [Homo sapiens]
          Length = 450

 Score =  114 bits (285), Expect = 1e-25
 Identities = 88/318 (27%), Positives = 156/318 (49%), Gaps = 11/318 (3%)

Query: 47  EEQNFKKMI-ESEYSMRLRLLNEECEQNLQRQQECISDL----NLRETLLN-QAIKLATE 100
           EE   +K+I E +Y  ++   N+E + NL ++      L    +LR+ ++  Q  K+   
Sbjct: 133 EECRVQKLIKEMDYLWKI---NQETQNNLNQETSKFCSLVDYVSLRKVIITIQYQKMHIF 189

Query: 101 LEEMFQEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEGTLALLKNAK 160
           L+E  Q  LQ L R  +E  ++L++S+ R ++ +  +  +  EL +      + LL++  
Sbjct: 190 LDEEEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRELWETYHMPDVELLQDVG 249

Query: 161 YSLERSKSLLLEHLEPAHITDLSLCHIRGLSSMFRVLQRHLTLDPETAHPCLALSEDLRT 220
               R+    +   +P +    S C I G+  M    +    L  E     ++LSED+R 
Sbjct: 250 NISARTDLAQMPKPQPVNPELTSWC-ITGVLDMLNNFRVDNALSTEMTPCYISLSEDVRR 308

Query: 221 MRLRHGQQDGAGNPERLDFSAMVLAAESFTSGRHYWEVDVEKATRWQVGIYHGSADAKGS 280
           +      +    +P+ ++ S  V  A++FTSG+HYWEVDV  ++ W +G+   S  A  +
Sbjct: 309 VIFGDDHRSAPMDPQGVE-SFAVWCAQAFTSGKHYWEVDVTHSSNWILGVCRDSRTADTN 367

Query: 281 TARASGEKVLLTGSVMGTEWTLWVFPPLKRLFLEKKLDTVGVFLDCEHGQISFYNVTEMS 340
               S +      S     ++L    P    ++++ L  VGVFLD ++G +SF++V++ S
Sbjct: 368 IVIDSDKTFFSISSKTSNHYSLSTNSPPLIQYVQRPLGWVGVFLDYDNGSVSFFDVSKGS 427

Query: 341 LIYNFSHCAFQGALRPVF 358
           LIY F   +F   LRP F
Sbjct: 428 LIYGFPPSSFSSPLRPFF 445


>gi|239744353 PREDICTED: tripartite motif-containing protein
           64C-like isoform 2 [Homo sapiens]
          Length = 450

 Score =  114 bits (285), Expect = 1e-25
 Identities = 88/318 (27%), Positives = 156/318 (49%), Gaps = 11/318 (3%)

Query: 47  EEQNFKKMI-ESEYSMRLRLLNEECEQNLQRQQECISDL----NLRETLLN-QAIKLATE 100
           EE   +K+I E +Y  ++   N+E + NL ++      L    +LR+ ++  Q  K+   
Sbjct: 133 EECRVQKLIKEMDYLWKI---NQETQNNLNQETSKFCSLVDYVSLRKVIITIQYQKMHIF 189

Query: 101 LEEMFQEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEGTLALLKNAK 160
           L+E  Q  LQ L R  +E  ++L++S+ R ++ +  +  +  EL +      + LL++  
Sbjct: 190 LDEEEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRELWETYHMPDVELLQDVG 249

Query: 161 YSLERSKSLLLEHLEPAHITDLSLCHIRGLSSMFRVLQRHLTLDPETAHPCLALSEDLRT 220
               R+    +   +P +    S C I G+  M    +    L  E     ++LSED+R 
Sbjct: 250 NISARTDLAQMPKPQPVNPELTSWC-ITGVLDMLNNFRVDNALSTEMTPCYISLSEDVRR 308

Query: 221 MRLRHGQQDGAGNPERLDFSAMVLAAESFTSGRHYWEVDVEKATRWQVGIYHGSADAKGS 280
           +      +    +P+ ++ S  V  A++FTSG+HYWEVDV  ++ W +G+   S  A  +
Sbjct: 309 VIFGDDHRSAPMDPQGVE-SFAVWCAQAFTSGKHYWEVDVTHSSNWILGVCRDSRTADTN 367

Query: 281 TARASGEKVLLTGSVMGTEWTLWVFPPLKRLFLEKKLDTVGVFLDCEHGQISFYNVTEMS 340
               S +      S     ++L    P    ++++ L  VGVFLD ++G +SF++V++ S
Sbjct: 368 IVIDSDKTFFSISSKTSNHYSLSTNSPPLIQYVQRPLGWVGVFLDYDNGSVSFFDVSKGS 427

Query: 341 LIYNFSHCAFQGALRPVF 358
           LIY F   +F   LRP F
Sbjct: 428 LIYGFPPSSFSSPLRPFF 445


>gi|27484954 PREDICTED: similar to ring finger protein 18 [Homo
           sapiens]
          Length = 452

 Score =  114 bits (285), Expect = 1e-25
 Identities = 91/328 (27%), Positives = 157/328 (47%), Gaps = 20/328 (6%)

Query: 37  EQERMAMIQEEEQNFKKMIESEYSMRLRLLNEECEQNLQRQQECISDLNLR-ETLLNQAI 95
           E+ +  ++Q+ +  ++K  E+  ++ +      C ++          +NLR E +  +  
Sbjct: 134 EEHQEKLLQKMQSLWEKACENHRNLNVETTRTRCWKDY---------VNLRLEAIRAEYQ 184

Query: 96  KLATELEEMFQEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEGTLAL 155
           K+     E  +  L+ L + G++   +L  S+A+ + +   L  +  EL + C +  + L
Sbjct: 185 KMPAFHHEEEKHNLEMLKKKGKDIFHRLHLSKAKMAHRREILRGMYEELNEMCHKPDVEL 244

Query: 156 LKNAKYSLERSKSLLLEHLEPAHITDLSLCHIRGLSSMFRVLQRHLTLDPETAHPCLALS 215
           L+     L RS+S+LL   +P +  +LS   I GL       + H+TL  E A+  + L 
Sbjct: 245 LQAFGDILHRSESVLLHMPQPLN-PELSAGPITGLRDRLNQFRVHITLHHEEANSDIFLC 303

Query: 216 EDLRTMRLRHGQQDG---AGNPERLDFSAMVLAAESFTSGRHYWEVDVEKATRWQVGIYH 272
           E LR+M +    QD       P     S +   A++FTSG++YWEV V  +  W  G+ +
Sbjct: 304 EILRSMCIGCDHQDVPYFTATPR----SFLAWGAQTFTSGKYYWEVHVGDSWNWAFGVCN 359

Query: 273 GSADAKGSTARASGEKVL-LTGSVMGT-EWTLWVFPPLKRLFLEKKLDTVGVFLDCEHGQ 330
                K    +  GE  L L G V    + +L+   PL   ++ +    VG+FLDCE   
Sbjct: 360 MYWKEKNQNEKIDGEDGLFLLGCVKNDIQRSLFTTSPLLLQYIPRPTSRVGLFLDCEAKT 419

Query: 331 ISFYNVTEMSLIYNFSHCAFQGALRPVF 358
           +SF +V + SLIY   +C+F   LRP+F
Sbjct: 420 VSFVDVNQSSLIYTIPNCSFSPPLRPIF 447


>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
          Length = 468

 Score =  114 bits (285), Expect = 1e-25
 Identities = 97/360 (26%), Positives = 161/360 (44%), Gaps = 48/360 (13%)

Query: 5   IQEAAENYRKLFQEILNTSREKLEAAKSILTDEQERMAMIQEEEQNFKKMIESEYSMRLR 64
           I++AA +YRK F   +   +++L   + +++ + ++   ++E  +N ++ + SE+     
Sbjct: 133 IEKAAIHYRKRFCSYIQPLKKQLADLQKLISTQSKKPLELREMVENQRQELSSEF----- 187

Query: 65  LLNEECEQNLQRQQECISDLNLRETLLNQAIKLATELEEMFQEMLQRLGRVGRENMEKLK 124
              E   Q L R+Q+ +                           L RL    ++N +KL 
Sbjct: 188 ---EHLNQFLDREQQAV---------------------------LSRLAEEEKDNQQKLS 217

Query: 125 ESE---ARASEQVRSLLKLIVELEKKCGEGTLALLKNAKYSLERSKSLLLEHLEPAHITD 181
            +    +  S  ++S L  +VEL +      L LL   K   E S++     +   H+  
Sbjct: 218 ANITAFSNYSATLKSQLSKVVELSEL---SELELLSQIKIFYE-SENESSPSIFSIHLKR 273

Query: 182 LSLCHIRGLSSMFRVLQR---HLTLDPETAHPCLALSEDLRTMRLRHGQQDGAGNPERLD 238
                    S++ R++++    + LDPETAHP L +SED + +R    +Q   G P+R  
Sbjct: 274 DGCSFPPQYSALQRIIKKFKVEIILDPETAHPNLIVSEDKKRVRFTKRKQKVPGFPKRFT 333

Query: 239 FSAMVLAAESFTSGRHYWEVDVEKATRWQVGIYHGSADAKGSTARASGEKVLLTGSVMGT 298
              +VL    F SGRH+WE++V   + W +GI   S   K     ++ ++          
Sbjct: 334 VKPVVLGFPYFHSGRHFWEIEVGDKSEWAIGICKDSLPTKARRPSSAQQECWRIELQDDG 393

Query: 299 EWTLWVFPPLKRLFLEKKLDTVGVFLDCEHGQISFYNVTEMSLIYNFSHCAFQGALRPVF 358
                 FP    L LE K   +G+FLD E G+ISFYN+ E S I  F+   F G LRP F
Sbjct: 394 YHAPGAFP--TPLLLEVKARAIGIFLDYEMGEISFYNMAEKSHICTFTD-TFTGPLRPYF 450


>gi|239755486 PREDICTED: tripartite motif-containing protein
           64C-like isoform 2 [Homo sapiens]
          Length = 447

 Score =  114 bits (284), Expect = 2e-25
 Identities = 86/315 (27%), Positives = 154/315 (48%), Gaps = 8/315 (2%)

Query: 47  EEQNFKKMI-ESEYSMRLRLLNEECEQNLQRQQECISDL--NLRETLLNQAIKLATELEE 103
           EE   +K+I E +Y  ++   N+E + NL ++      L  + R  ++ +  K+   L+E
Sbjct: 133 EECRVQKLIKEMDYLWKI---NQETQNNLNQETSKFCSLVEDKRNRIVYRYQKMHIFLDE 189

Query: 104 MFQEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEGTLALLKNAKYSL 163
             Q  LQ L R  +E  ++L++S+ R ++ +  +  +  EL +      + LL++     
Sbjct: 190 EEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRELWETYHMPDVELLQDVGNIS 249

Query: 164 ERSKSLLLEHLEPAHITDLSLCHIRGLSSMFRVLQRHLTLDPETAHPCLALSEDLRTMRL 223
            R+    +   +P +    S C I G+  M    +    L  E     ++LSED+R +  
Sbjct: 250 ARTDLAQMPKPQPVNPELTSWC-ITGVLDMLNNFRVDNALSTEMTPCYISLSEDVRRVIF 308

Query: 224 RHGQQDGAGNPERLDFSAMVLAAESFTSGRHYWEVDVEKATRWQVGIYHGSADAKGSTAR 283
               +    +P+ ++ S  V  A++FTSG+HYWEVDV  ++ W +G+   S  A  +   
Sbjct: 309 GDDHRSAPMDPQGVE-SFAVWCAQAFTSGKHYWEVDVTHSSNWILGVCRDSRTADTNIVI 367

Query: 284 ASGEKVLLTGSVMGTEWTLWVFPPLKRLFLEKKLDTVGVFLDCEHGQISFYNVTEMSLIY 343
            S +      S     ++L    P    ++++ L  VGVFLD ++G +SF++V++ SLIY
Sbjct: 368 DSDKTFFSISSKTSNHYSLSTNSPPLIQYVQRPLGWVGVFLDYDNGSVSFFDVSKGSLIY 427

Query: 344 NFSHCAFQGALRPVF 358
            F   +F   LRP F
Sbjct: 428 GFPPSSFSSPLRPFF 442


>gi|239750044 PREDICTED: tripartite motif-containing protein
           64C-like isoform 2 [Homo sapiens]
          Length = 447

 Score =  114 bits (284), Expect = 2e-25
 Identities = 86/315 (27%), Positives = 154/315 (48%), Gaps = 8/315 (2%)

Query: 47  EEQNFKKMI-ESEYSMRLRLLNEECEQNLQRQQECISDL--NLRETLLNQAIKLATELEE 103
           EE   +K+I E +Y  ++   N+E + NL ++      L  + R  ++ +  K+   L+E
Sbjct: 133 EECRVQKLIKEMDYLWKI---NQETQNNLNQETSKFCSLVEDKRNRIVYRYQKMHIFLDE 189

Query: 104 MFQEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEGTLALLKNAKYSL 163
             Q  LQ L R  +E  ++L++S+ R ++ +  +  +  EL +      + LL++     
Sbjct: 190 EEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRELWETYHMPDVELLQDVGNIS 249

Query: 164 ERSKSLLLEHLEPAHITDLSLCHIRGLSSMFRVLQRHLTLDPETAHPCLALSEDLRTMRL 223
            R+    +   +P +    S C I G+  M    +    L  E     ++LSED+R +  
Sbjct: 250 ARTDLAQMPKPQPVNPELTSWC-ITGVLDMLNNFRVDNALSTEMTPCYISLSEDVRRVIF 308

Query: 224 RHGQQDGAGNPERLDFSAMVLAAESFTSGRHYWEVDVEKATRWQVGIYHGSADAKGSTAR 283
               +    +P+ ++ S  V  A++FTSG+HYWEVDV  ++ W +G+   S  A  +   
Sbjct: 309 GDDHRSAPMDPQGVE-SFAVWCAQAFTSGKHYWEVDVTHSSNWILGVCRDSRTADTNIVI 367

Query: 284 ASGEKVLLTGSVMGTEWTLWVFPPLKRLFLEKKLDTVGVFLDCEHGQISFYNVTEMSLIY 343
            S +      S     ++L    P    ++++ L  VGVFLD ++G +SF++V++ SLIY
Sbjct: 368 DSDKTFFSISSKTSNHYSLSTNSPPLIQYVQRPLGWVGVFLDYDNGSVSFFDVSKGSLIY 427

Query: 344 NFSHCAFQGALRPVF 358
            F   +F   LRP F
Sbjct: 428 GFPPSSFSSPLRPFF 442


>gi|89034675 PREDICTED: similar to hCG1802386 [Homo sapiens]
          Length = 452

 Score =  114 bits (284), Expect = 2e-25
 Identities = 92/326 (28%), Positives = 155/326 (47%), Gaps = 18/326 (5%)

Query: 37  EQERMAMIQEEEQNFKKMIESEYSMRLRLLNEECEQNLQRQQECISDLNLR-ETLLNQAI 95
           E+ R  ++++ +  ++KM E+  ++ +      C ++          ++LR E +  +  
Sbjct: 134 EERREELLRKMQSLWRKMCENHRNLNMATNRIRCWKDY---------VSLRIEAIRAEYH 184

Query: 96  KLATELEEMFQEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEGTLAL 155
           K+     E  Q  L+RL + G +  ++L +S+AR       L  +  +L + C +  + L
Sbjct: 185 KMVAFFHEEEQRHLERLQKEGEDIFQQLNKSKARMEHSRELLRGMYEDLRQMCHKAVVEL 244

Query: 156 LKNAKYSLERSKSLLLEHLEPAHITDLSLCHIRGLSSMFRVLQRHLTLDPETAHPCLALS 215
           L++    L+R +SLLL+  EP +  + S   I GL    +  + +LTL    A   + L 
Sbjct: 245 LQSFGDILQRYESLLLQVSEPVN-PEFSAGPIIGLMDRLKGFRVYLTLQHARASSHIFLH 303

Query: 216 EDLRTMRLRHGQQDGAGNPERLDFSAMVL--AAESFTSGRHYWEVDVEKATRWQVGIYHG 273
            DLR+M++    Q    +P   D S   L   A+ F SG+ YWE ++  +  W  G+ H 
Sbjct: 304 GDLRSMKVGCDPQH---DPNITDKSECFLQWGADFFISGKFYWEFNMGHSWNWAFGVCHN 360

Query: 274 SADAKGSTARASGEKVL-LTGSVM-GTEWTLWVFPPLKRLFLEKKLDTVGVFLDCEHGQI 331
               K       GE  L L G V   T  +L+   PL   ++ +  DTVG+FLDCE   +
Sbjct: 361 YWKEKRQNDMIDGEVGLFLLGCVKEDTHCSLFTTSPLVMQYVPRPTDTVGLFLDCEGRTV 420

Query: 332 SFYNVTEMSLIYNFSHCAFQGALRPV 357
           SF +V   SLIY   +C+F   L P+
Sbjct: 421 SFVDVDRSSLIYTIPNCSFSPPLWPI 446


>gi|239744355 PREDICTED: tripartite motif-containing protein
           64C-like isoform 1 [Homo sapiens]
          Length = 447

 Score =  114 bits (284), Expect = 2e-25
 Identities = 86/315 (27%), Positives = 154/315 (48%), Gaps = 8/315 (2%)

Query: 47  EEQNFKKMI-ESEYSMRLRLLNEECEQNLQRQQECISDL--NLRETLLNQAIKLATELEE 103
           EE   +K+I E +Y  ++   N+E + NL ++      L  + R  ++ +  K+   L+E
Sbjct: 133 EECRVQKLIKEMDYLWKI---NQETQNNLNQETSKFCSLVEDKRNRIVYRYQKMHIFLDE 189

Query: 104 MFQEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEGTLALLKNAKYSL 163
             Q  LQ L R  +E  ++L++S+ R ++ +  +  +  EL +      + LL++     
Sbjct: 190 EEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRELWETYHMPDVELLQDVGNIS 249

Query: 164 ERSKSLLLEHLEPAHITDLSLCHIRGLSSMFRVLQRHLTLDPETAHPCLALSEDLRTMRL 223
            R+    +   +P +    S C I G+  M    +    L  E     ++LSED+R +  
Sbjct: 250 ARTDLAQMPKPQPVNPELTSWC-ITGVLDMLNNFRVDNALSTEMTPCYISLSEDVRRVIF 308

Query: 224 RHGQQDGAGNPERLDFSAMVLAAESFTSGRHYWEVDVEKATRWQVGIYHGSADAKGSTAR 283
               +    +P+ ++ S  V  A++FTSG+HYWEVDV  ++ W +G+   S  A  +   
Sbjct: 309 GDDHRSAPMDPQGVE-SFAVWCAQAFTSGKHYWEVDVTHSSNWILGVCRDSRTADTNIVI 367

Query: 284 ASGEKVLLTGSVMGTEWTLWVFPPLKRLFLEKKLDTVGVFLDCEHGQISFYNVTEMSLIY 343
            S +      S     ++L    P    ++++ L  VGVFLD ++G +SF++V++ SLIY
Sbjct: 368 DSDKTFFSISSKTSNHYSLSTNSPPLIQYVQRPLGWVGVFLDYDNGSVSFFDVSKGSLIY 427

Query: 344 NFSHCAFQGALRPVF 358
            F   +F   LRP F
Sbjct: 428 GFPPSSFSSPLRPFF 442


>gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens]
          Length = 526

 Score =  113 bits (283), Expect = 3e-25
 Identities = 71/180 (39%), Positives = 95/180 (52%), Gaps = 6/180 (3%)

Query: 201 LTLDPETAHPCLALSEDLRTMRLRHGQQDGAGNPERLDFSAMVLAAESFTSGRHYWEVDV 260
           +TLDP+TAHP L L ED +++RL   +Q      ER D    VL  E+FTSGRHYWEV+V
Sbjct: 305 VTLDPDTAHPHLFLYEDSKSVRLEDSRQKLPEKTERFDSWPCVLGRETFTSGRHYWEVEV 364

Query: 261 EKATRWQVGIYHGSADAKGSTARASGEKVLLTGSVMGTEWTLWVFPPLKR-LFLEKKLDT 319
              T W +G+   +   KG     + E       + G  +  W   PL+  L L      
Sbjct: 365 GDRTDWAIGVCRENVMKKGFDP-MTPENGFWAVELYGNGY--WALTPLRTPLPLAGPPRR 421

Query: 320 VGVFLDCEHGQISFYNVTEMSLIYNFSHCAFQGALRPVFSLCIPNGDTSPDSLTILQHGP 379
           VG+FLD E G ISFYN+ + S IY FS+  F G LRP F  C+ +    P ++  +  GP
Sbjct: 422 VGIFLDYESGDISFYNMNDGSDIYTFSNVTFSGPLRPFF--CLWSSGKKPLTICPIADGP 479


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.132    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,856,122
Number of Sequences: 37866
Number of extensions: 580990
Number of successful extensions: 4140
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 184
Number of HSP's successfully gapped in prelim test: 496
Number of HSP's that attempted gapping in prelim test: 2933
Number of HSP's gapped (non-prelim): 1353
length of query: 387
length of database: 18,247,518
effective HSP length: 104
effective length of query: 283
effective length of database: 14,309,454
effective search space: 4049575482
effective search space used: 4049575482
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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