Guide to the Human Genome
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Search of human proteins with 27436883

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27436883 ets homologous factor [Homo sapiens]
         (300 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27436883 ets homologous factor [Homo sapiens]                      642   0.0  
gi|38201717 E74-like factor 5 ESE-2a [Homo sapiens]                   211   5e-55
gi|4557551 E74-like factor 5 ESE-2b [Homo sapiens]                    211   5e-55
gi|166851840 E74-like factor 3 (ets domain transcription factor,...   179   3e-45
gi|167235023 E74-like factor 3 (ets domain transcription factor,...   179   3e-45
gi|7706731 ets variant 7 [Homo sapiens]                               103   2e-22
gi|42544172 E74-like factor 2 (ets domain transcription factor) ...    99   6e-21
gi|6857816 E74-like factor 2 (ets domain transcription factor) i...    99   6e-21
gi|187608767 E74-like factor 4 [Homo sapiens]                          97   2e-20
gi|4503555 E74-like factor 4 [Homo sapiens]                            97   2e-20
gi|27363484 E74-like factor 1 (ets domain transcription factor) ...    95   7e-20
gi|223941929 E74-like factor 1 (ets domain transcription factor)...    95   7e-20
gi|4758300 ets-related isoform 2 [Homo sapiens]                        93   2e-19
gi|7110593 Friend leukemia virus integration 1 [Homo sapiens]          90   3e-18
gi|209954808 ets-related isoform 4 [Homo sapiens]                      89   5e-18
gi|33667107 ets-related isoform 1 [Homo sapiens]                       89   5e-18
gi|209954797 ets-related isoform 3 [Homo sapiens]                      89   5e-18
gi|6912580 SAM pointed domain containing ets transcription facto...    86   3e-17
gi|34452721 GA binding protein transcription factor, alpha subun...    86   5e-17
gi|44955921 ELK3 protein [Homo sapiens]                                84   2e-16
gi|166362732 ELK1 protein [Homo sapiens]                               84   2e-16
gi|166362730 ELK1 protein [Homo sapiens]                               84   2e-16
gi|11496882 ELK4 protein isoform b [Homo sapiens]                      82   6e-16
gi|41872448 ELK4 protein isoform a [Homo sapiens]                      82   6e-16
gi|4503611 ets variant 6 [Homo sapiens]                                81   1e-15
gi|153791178 ets variant gene 2 [Homo sapiens]                         78   8e-15
gi|4758316 ets variant gene 5 (ets-related molecule) [Homo sapiens]    76   4e-14
gi|253683437 ets variant gene 1 isoform f [Homo sapiens]               74   1e-13
gi|253683435 ets variant gene 1 isoform e [Homo sapiens]               74   1e-13
gi|253683433 ets variant gene 1 isoform d [Homo sapiens]               74   1e-13

>gi|27436883 ets homologous factor [Homo sapiens]
          Length = 300

 Score =  642 bits (1657), Expect = 0.0
 Identities = 300/300 (100%), Positives = 300/300 (100%)

Query: 1   MILEGGGVMNLNPGNNLLHQPPAWTDSYSTCNVSSGFFGGQWHEIHPQYWTKYQVWEWLQ 60
           MILEGGGVMNLNPGNNLLHQPPAWTDSYSTCNVSSGFFGGQWHEIHPQYWTKYQVWEWLQ
Sbjct: 1   MILEGGGVMNLNPGNNLLHQPPAWTDSYSTCNVSSGFFGGQWHEIHPQYWTKYQVWEWLQ 60

Query: 61  HLLDTNQLDANCIPFQEFDINGEHLCSMSLQEFTRAAGTAGQLLYSNLQHLKWNGQCSSD 120
           HLLDTNQLDANCIPFQEFDINGEHLCSMSLQEFTRAAGTAGQLLYSNLQHLKWNGQCSSD
Sbjct: 61  HLLDTNQLDANCIPFQEFDINGEHLCSMSLQEFTRAAGTAGQLLYSNLQHLKWNGQCSSD 120

Query: 121 LFQSTHNVIVKTEQTEPSIMNTWKDENYLYDTNYGSTVDLLDSKTFCRAQISMTTTSHLP 180
           LFQSTHNVIVKTEQTEPSIMNTWKDENYLYDTNYGSTVDLLDSKTFCRAQISMTTTSHLP
Sbjct: 121 LFQSTHNVIVKTEQTEPSIMNTWKDENYLYDTNYGSTVDLLDSKTFCRAQISMTTTSHLP 180

Query: 181 VAESPDMKKEQDPPAKCHTKKHNPRGTHLWEFIRDILLNPDKNPGLIKWEDRSEGVFRFL 240
           VAESPDMKKEQDPPAKCHTKKHNPRGTHLWEFIRDILLNPDKNPGLIKWEDRSEGVFRFL
Sbjct: 181 VAESPDMKKEQDPPAKCHTKKHNPRGTHLWEFIRDILLNPDKNPGLIKWEDRSEGVFRFL 240

Query: 241 KSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNARGWRENEN 300
           KSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNARGWRENEN
Sbjct: 241 KSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNARGWRENEN 300


>gi|38201717 E74-like factor 5 ESE-2a [Homo sapiens]
          Length = 265

 Score =  211 bits (538), Expect = 5e-55
 Identities = 115/283 (40%), Positives = 160/283 (56%), Gaps = 56/283 (19%)

Query: 23  AWTDSYSTCNVSSGF-----FGGQWHEIHPQYWTKYQVWEWLQHLLDTNQLDANCIPFQE 77
           +WTD +S       F         W  +HP+YWTK  VWEWLQ   D  +LD NCI F  
Sbjct: 32  SWTDLFSNEEYYPAFEHQTACDSYWTSVHPEYWTKRHVWEWLQFCCDQYKLDTNCISFCN 91

Query: 78  FDINGEHLCSMSLQEFTRAAGTAGQLLYSNLQHLKWNGQCSSDLFQSTHNVIVKTEQTEP 137
           F+I+G  LCSM+ +EF  AAG  G+ LY  LQ+++  G          ++     E+++ 
Sbjct: 92  FNISGLQLCSMTQEEFVEAAGLCGEYLYFILQNIRTQG----------YSFFNDAEESKA 141

Query: 138 SIMNTWKDENYLYDTNYGSTVDLLDSKTFCRAQISMTTTSHLPVAESPDMKKEQDPPAKC 197
           +I + + D N L  +                                    K QD    C
Sbjct: 142 TIKD-YADSNCLKTSGI----------------------------------KSQD----C 162

Query: 198 HTKKHNP-RGTHLWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKSEAVAQLWGKKKNNS 256
           H+      + +HLWEF+RD+LL+P++N G+++WEDR +G+FR +KSEA+A++WG++K N 
Sbjct: 163 HSHSRTSLQSSHLWEFVRDLLLSPEENCGILEWEDREQGIFRVVKSEALAKMWGQRKKND 222

Query: 257 SMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNARGWRENE 299
            MTYEKLSRA+RYYYK  ILERVD RRLVYKFGKNA GW+E++
Sbjct: 223 RMTYEKLSRALRYYYKTGILERVD-RRLVYKFGKNAHGWQEDK 264


>gi|4557551 E74-like factor 5 ESE-2b [Homo sapiens]
          Length = 255

 Score =  211 bits (538), Expect = 5e-55
 Identities = 115/283 (40%), Positives = 160/283 (56%), Gaps = 56/283 (19%)

Query: 23  AWTDSYSTCNVSSGF-----FGGQWHEIHPQYWTKYQVWEWLQHLLDTNQLDANCIPFQE 77
           +WTD +S       F         W  +HP+YWTK  VWEWLQ   D  +LD NCI F  
Sbjct: 22  SWTDLFSNEEYYPAFEHQTACDSYWTSVHPEYWTKRHVWEWLQFCCDQYKLDTNCISFCN 81

Query: 78  FDINGEHLCSMSLQEFTRAAGTAGQLLYSNLQHLKWNGQCSSDLFQSTHNVIVKTEQTEP 137
           F+I+G  LCSM+ +EF  AAG  G+ LY  LQ+++  G          ++     E+++ 
Sbjct: 82  FNISGLQLCSMTQEEFVEAAGLCGEYLYFILQNIRTQG----------YSFFNDAEESKA 131

Query: 138 SIMNTWKDENYLYDTNYGSTVDLLDSKTFCRAQISMTTTSHLPVAESPDMKKEQDPPAKC 197
           +I + + D N L  +                                    K QD    C
Sbjct: 132 TIKD-YADSNCLKTSGI----------------------------------KSQD----C 152

Query: 198 HTKKHNP-RGTHLWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKSEAVAQLWGKKKNNS 256
           H+      + +HLWEF+RD+LL+P++N G+++WEDR +G+FR +KSEA+A++WG++K N 
Sbjct: 153 HSHSRTSLQSSHLWEFVRDLLLSPEENCGILEWEDREQGIFRVVKSEALAKMWGQRKKND 212

Query: 257 SMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNARGWRENE 299
            MTYEKLSRA+RYYYK  ILERVD RRLVYKFGKNA GW+E++
Sbjct: 213 RMTYEKLSRALRYYYKTGILERVD-RRLVYKFGKNAHGWQEDK 254


>gi|166851840 E74-like factor 3 (ets domain transcription factor,
           epithelial-specific ) [Homo sapiens]
          Length = 371

 Score =  179 bits (453), Expect = 3e-45
 Identities = 81/99 (81%), Positives = 92/99 (92%)

Query: 201 KHNPRGTHLWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKSEAVAQLWGKKKNNSSMTY 260
           KH PRGTHLWEFIRDIL++P+ N GL+KWE+R EGVF+FL+SEAVAQLWG+KK NS+MTY
Sbjct: 267 KHAPRGTHLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTY 326

Query: 261 EKLSRAMRYYYKREILERVDGRRLVYKFGKNARGWRENE 299
           EKLSRAMRYYYKREILERVDGRRLVYKFGKN+ GW+E E
Sbjct: 327 EKLSRAMRYYYKREILERVDGRRLVYKFGKNSSGWKEEE 365



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 24/70 (34%), Positives = 41/70 (58%)

Query: 42  WHEIHPQYWTKYQVWEWLQHLLDTNQLDANCIPFQEFDINGEHLCSMSLQEFTRAAGTAG 101
           W    PQ+W+K QV +W+ + ++ N+ DA+ I F   D++G  LC+ +L+E     G  G
Sbjct: 59  WLGEQPQFWSKTQVLDWISYQVEKNKYDASAIDFSRCDMDGATLCNCALEELRLVFGPLG 118

Query: 102 QLLYSNLQHL 111
             L++ L+ L
Sbjct: 119 DQLHAQLRDL 128


>gi|167235023 E74-like factor 3 (ets domain transcription factor,
           epithelial-specific ) [Homo sapiens]
          Length = 371

 Score =  179 bits (453), Expect = 3e-45
 Identities = 81/99 (81%), Positives = 92/99 (92%)

Query: 201 KHNPRGTHLWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKSEAVAQLWGKKKNNSSMTY 260
           KH PRGTHLWEFIRDIL++P+ N GL+KWE+R EGVF+FL+SEAVAQLWG+KK NS+MTY
Sbjct: 267 KHAPRGTHLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTY 326

Query: 261 EKLSRAMRYYYKREILERVDGRRLVYKFGKNARGWRENE 299
           EKLSRAMRYYYKREILERVDGRRLVYKFGKN+ GW+E E
Sbjct: 327 EKLSRAMRYYYKREILERVDGRRLVYKFGKNSSGWKEEE 365



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 24/70 (34%), Positives = 41/70 (58%)

Query: 42  WHEIHPQYWTKYQVWEWLQHLLDTNQLDANCIPFQEFDINGEHLCSMSLQEFTRAAGTAG 101
           W    PQ+W+K QV +W+ + ++ N+ DA+ I F   D++G  LC+ +L+E     G  G
Sbjct: 59  WLGEQPQFWSKTQVLDWISYQVEKNKYDASAIDFSRCDMDGATLCNCALEELRLVFGPLG 118

Query: 102 QLLYSNLQHL 111
             L++ L+ L
Sbjct: 119 DQLHAQLRDL 128


>gi|7706731 ets variant 7 [Homo sapiens]
          Length = 341

 Score =  103 bits (257), Expect = 2e-22
 Identities = 83/310 (26%), Positives = 141/310 (45%), Gaps = 33/310 (10%)

Query: 7   GVMNLNPGNNLLHQPPAWTDSYSTCNVSSGFFG--------GQWHEIHPQYWTKYQVWEW 58
           G + ++P + +   PP  T   + C       G        G+   I P  W++  V  W
Sbjct: 4   GELAISPISPVAAMPPLGTHVQARCEAQINLLGEGGICKLPGRLR-IQPALWSREDVLHW 62

Query: 59  LQHLLDTNQLDANCIPFQEFDINGEHLCSMSLQEFTRAAGTAGQLLYSNLQHLKWN---- 114
           L+       L   C     F++NG  LC ++  +F   A ++G +LY  LQ++K      
Sbjct: 63  LRWAEQEYSLP--CTAEHGFEMNGRALCILTKDDFRHRAPSSGDVLYELLQYIKTQRRAL 120

Query: 115 --GQCSSDLFQ----STHNVIVKTEQTEPSIMNTWKDENYLYDTNYGSTVDL--LDSKTF 166
             G     +F+    + H+ +   E T PS M+T +  + L   + G T +   LD    
Sbjct: 121 VCGPFFGGIFRLKTPTQHSPVPPEEVTGPSQMDTRRG-HLLQPPDPGLTSNFGHLDDPGL 179

Query: 167 CR------AQISMTTTSHLPVAESPDMKKEQDPPAKCHTKKHNPRGTHLWEFIRDILLNP 220
            R        +++   + L             P A    +  + R   LW+++  +LL+ 
Sbjct: 180 ARWTPGKEESLNLCHCAELGCRTQGVCSFPAMPQAPIDGRIADCR--LLWDYVYQLLLDT 237

Query: 221 DKNPGLIKWEDRSEGVFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVD 280
              P  IKWED+   +FR +    +A+LWG  KN  +MTYEK+SRA+R+YYK  I+++  
Sbjct: 238 RYEP-YIKWEDKDAKIFRVVDPNGLARLWGNHKNRVNMTYEKMSRALRHYYKLNIIKKEP 296

Query: 281 GRRLVYKFGK 290
           G++L+++F K
Sbjct: 297 GQKLLFRFLK 306


>gi|42544172 E74-like factor 2 (ets domain transcription factor)
           isoform 1 [Homo sapiens]
          Length = 581

 Score = 98.6 bits (244), Expect = 6e-21
 Identities = 42/82 (51%), Positives = 61/82 (74%)

Query: 207 THLWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKSEAVAQLWGKKKNNSSMTYEKLSRA 266
           T+LWEF+ D+L + +  P  IKW  R +G+F+ + S+AV++LWGK KN   M YE + RA
Sbjct: 196 TYLWEFLLDLLQDKNTCPRYIKWTQREKGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRA 255

Query: 267 MRYYYKREILERVDGRRLVYKF 288
           +RYYY+R IL +V+G+RLVY+F
Sbjct: 256 LRYYYQRGILAKVEGQRLVYQF 277


>gi|6857816 E74-like factor 2 (ets domain transcription factor)
           isoform 2 [Homo sapiens]
          Length = 533

 Score = 98.6 bits (244), Expect = 6e-21
 Identities = 42/82 (51%), Positives = 61/82 (74%)

Query: 207 THLWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKSEAVAQLWGKKKNNSSMTYEKLSRA 266
           T+LWEF+ D+L + +  P  IKW  R +G+F+ + S+AV++LWGK KN   M YE + RA
Sbjct: 148 TYLWEFLLDLLQDKNTCPRYIKWTQREKGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRA 207

Query: 267 MRYYYKREILERVDGRRLVYKF 288
           +RYYY+R IL +V+G+RLVY+F
Sbjct: 208 LRYYYQRGILAKVEGQRLVYQF 229


>gi|187608767 E74-like factor 4 [Homo sapiens]
          Length = 663

 Score = 96.7 bits (239), Expect = 2e-20
 Identities = 44/99 (44%), Positives = 67/99 (67%), Gaps = 2/99 (2%)

Query: 192 DPPAKCHTKKHNPRGT--HLWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKSEAVAQLW 249
           DP      K  + +G+  +LWEF+  +L + +  P  IKW  R +G+F+ + S+AV++LW
Sbjct: 192 DPSIPIRKKSKDGKGSTIYLWEFLLALLQDRNTCPKYIKWTQREKGIFKLVDSKAVSKLW 251

Query: 250 GKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKF 288
           GK+KN   M YE + RA+RYYY+R IL +V+G+RLVY+F
Sbjct: 252 GKQKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQF 290


>gi|4503555 E74-like factor 4 [Homo sapiens]
          Length = 663

 Score = 96.7 bits (239), Expect = 2e-20
 Identities = 44/99 (44%), Positives = 67/99 (67%), Gaps = 2/99 (2%)

Query: 192 DPPAKCHTKKHNPRGT--HLWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKSEAVAQLW 249
           DP      K  + +G+  +LWEF+  +L + +  P  IKW  R +G+F+ + S+AV++LW
Sbjct: 192 DPSIPIRKKSKDGKGSTIYLWEFLLALLQDRNTCPKYIKWTQREKGIFKLVDSKAVSKLW 251

Query: 250 GKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKF 288
           GK+KN   M YE + RA+RYYY+R IL +V+G+RLVY+F
Sbjct: 252 GKQKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQF 290


>gi|27363484 E74-like factor 1 (ets domain transcription factor)
           isoform a [Homo sapiens]
          Length = 619

 Score = 95.1 bits (235), Expect = 7e-20
 Identities = 52/126 (41%), Positives = 72/126 (57%), Gaps = 17/126 (13%)

Query: 180 PVAESPDMKKEQ----------DPPA---KCHTKKHNPRGT----HLWEFIRDILLNPDK 222
           P A SP+  K +          D PA       KK N  G     +LWEF+  +L +   
Sbjct: 164 PGASSPEQPKRKKGRKTKPPRPDSPATTPNISVKKKNKDGKGNTIYLWEFLLALLQDKAT 223

Query: 223 NPGLIKWEDRSEGVFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGR 282
            P  IKW  R +G+F+ + S+AV++LWGK KN   M YE + RA+RYYY+R IL +V+G+
Sbjct: 224 CPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQ 283

Query: 283 RLVYKF 288
           RLVY+F
Sbjct: 284 RLVYQF 289


>gi|223941929 E74-like factor 1 (ets domain transcription factor)
           isoform b [Homo sapiens]
          Length = 595

 Score = 95.1 bits (235), Expect = 7e-20
 Identities = 52/126 (41%), Positives = 72/126 (57%), Gaps = 17/126 (13%)

Query: 180 PVAESPDMKKEQ----------DPPA---KCHTKKHNPRGT----HLWEFIRDILLNPDK 222
           P A SP+  K +          D PA       KK N  G     +LWEF+  +L +   
Sbjct: 140 PGASSPEQPKRKKGRKTKPPRPDSPATTPNISVKKKNKDGKGNTIYLWEFLLALLQDKAT 199

Query: 223 NPGLIKWEDRSEGVFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGR 282
            P  IKW  R +G+F+ + S+AV++LWGK KN   M YE + RA+RYYY+R IL +V+G+
Sbjct: 200 CPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQ 259

Query: 283 RLVYKF 288
           RLVY+F
Sbjct: 260 RLVYQF 265


>gi|4758300 ets-related isoform 2 [Homo sapiens]
          Length = 462

 Score = 93.2 bits (230), Expect = 2e-19
 Identities = 71/249 (28%), Positives = 115/249 (46%), Gaps = 20/249 (8%)

Query: 47  PQYWTKYQVWEWLQHLLDTNQL-DANCIPFQEFDINGEHLCSMSLQEFTRAAGTAG-QLL 104
           P  W+   V +WL+  +    L D N + FQ  D  G+ LC M+  +F R   +    +L
Sbjct: 138 PTLWSTDHVRQWLEWAVKEYGLPDVNILLFQNID--GKELCKMTKDDFQRLTPSYNADIL 195

Query: 105 YSNLQHLKWNGQCSSDLFQSTHNVIVKTEQTEPSIMNTWKDENYLYDTNYGSTVDLLDSK 164
            S+L +L+      + L   T + + K  Q  P +M+  ++ +  Y+    S        
Sbjct: 196 LSHLHYLR-----ETPLPHLTSDDVDKALQNSPRLMHA-RNTDLPYEPPRRSAWTGHGHP 249

Query: 165 TFCRAQISMTTTSHLPVAESPDMKKEQDP-----PAKCHTKKHNPRGTHLWEFIRDILLN 219
           T    Q      S   V ++ D + + DP     P              LW+F+ + LL+
Sbjct: 250 T---PQSKAAQPSPSTVPKTEDQRPQLDPYQILGPTSSRLANPGSGQIQLWQFLLE-LLS 305

Query: 220 PDKNPGLIKWEDRSEGVFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERV 279
              N   I WE  + G F+    + VA+ WG++K+  +M Y+KLSRA+RYYY + I+ +V
Sbjct: 306 DSSNSSCITWEG-TNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKV 364

Query: 280 DGRRLVYKF 288
            G+R  YKF
Sbjct: 365 HGKRYAYKF 373


>gi|7110593 Friend leukemia virus integration 1 [Homo sapiens]
          Length = 452

 Score = 89.7 bits (221), Expect = 3e-18
 Identities = 68/249 (27%), Positives = 121/249 (48%), Gaps = 25/249 (10%)

Query: 47  PQYWTKYQVWEWLQHLL-DTNQLDANCIPFQEFDINGEHLCSMSLQEFTRAAGTAG-QLL 104
           P  WT+  V +WL+  + + + ++ +   FQ  D  G+ LC M+ ++F RA      ++L
Sbjct: 130 PTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMD--GKELCKMNKEDFLRATTLYNTEVL 187

Query: 105 YSNLQHLKWNGQCSSDLFQSTHNVIVKTEQTEPSIMNTWKDENYLYDTNYGSTVDLLDSK 164
            S+L +L+     SS L  +T      T  T+ S   + K++        G+  + ++S 
Sbjct: 188 LSHLSYLRE----SSLLAYNT------TSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSG 237

Query: 165 TFCRAQISMTTTSHLPVAESPDMKKEQDP-----PAKCHTKKHNPRGTHLWEFIRDILLN 219
                 +    T    ++++ + + + DP     P              LW+F+ + LL+
Sbjct: 238 LNKSPPLGGAQT----ISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLE-LLS 292

Query: 220 PDKNPGLIKWEDRSEGVFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERV 279
              N   I WE  + G F+    + VA+ WG++K+  +M Y+KLSRA+RYYY + I+ +V
Sbjct: 293 DSANASCITWEG-TNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKV 351

Query: 280 DGRRLVYKF 288
            G+R  YKF
Sbjct: 352 HGKRYAYKF 360


>gi|209954808 ets-related isoform 4 [Homo sapiens]
          Length = 387

 Score = 89.0 bits (219), Expect = 5e-18
 Identities = 73/278 (26%), Positives = 118/278 (42%), Gaps = 54/278 (19%)

Query: 47  PQYWTKYQVWEWLQHLLDTNQL-DANCIPFQEFDINGEHLCSMSLQEFTRAAGTAG-QLL 104
           P  W+   V +WL+  +    L D N + FQ  D  G+ LC M+  +F R   +    +L
Sbjct: 39  PTLWSTDHVRQWLEWAVKEYGLPDVNILLFQNID--GKELCKMTKDDFQRLTPSYNADIL 96

Query: 105 YSNLQHLKWNGQCSSDLFQSTHNVIVKTEQTEPSIMNTWKDENYLYDTNYGSTVDLL-DS 163
            S+L +L+      + L   T + + K  Q  P +M+           N G    +  ++
Sbjct: 97  LSHLHYLR-----ETPLPHLTSDDVDKALQNSPRLMHA---------RNTGGAAFIFPNT 142

Query: 164 KTFCRAQISMTTTSHLP----------------------------VAESPDMKKEQDP-- 193
             +  A   +TT   LP                            V ++ D + + DP  
Sbjct: 143 SVYPEATQRITTRPDLPYEPPRRSAWTGHGHPTPQSKAAQPSPSTVPKTEDQRPQLDPYQ 202

Query: 194 ---PAKCHTKKHNPRGTHLWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKSEAVAQLWG 250
              P              LW+F+ + LL+   N   I WE  + G F+    + VA+ WG
Sbjct: 203 ILGPTSSRLANPGSGQIQLWQFLLE-LLSDSSNSSCITWEG-TNGEFKMTDPDEVARRWG 260

Query: 251 KKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKF 288
           ++K+  +M Y+KLSRA+RYYY + I+ +V G+R  YKF
Sbjct: 261 ERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKF 298


>gi|33667107 ets-related isoform 1 [Homo sapiens]
          Length = 479

 Score = 89.0 bits (219), Expect = 5e-18
 Identities = 73/278 (26%), Positives = 118/278 (42%), Gaps = 54/278 (19%)

Query: 47  PQYWTKYQVWEWLQHLLDTNQL-DANCIPFQEFDINGEHLCSMSLQEFTRAAGTAG-QLL 104
           P  W+   V +WL+  +    L D N + FQ  D  G+ LC M+  +F R   +    +L
Sbjct: 131 PTLWSTDHVRQWLEWAVKEYGLPDVNILLFQNID--GKELCKMTKDDFQRLTPSYNADIL 188

Query: 105 YSNLQHLKWNGQCSSDLFQSTHNVIVKTEQTEPSIMNTWKDENYLYDTNYGSTVDLL-DS 163
            S+L +L+      + L   T + + K  Q  P +M+           N G    +  ++
Sbjct: 189 LSHLHYLR-----ETPLPHLTSDDVDKALQNSPRLMHA---------RNTGGAAFIFPNT 234

Query: 164 KTFCRAQISMTTTSHLP----------------------------VAESPDMKKEQDP-- 193
             +  A   +TT   LP                            V ++ D + + DP  
Sbjct: 235 SVYPEATQRITTRPDLPYEPPRRSAWTGHGHPTPQSKAAQPSPSTVPKTEDQRPQLDPYQ 294

Query: 194 ---PAKCHTKKHNPRGTHLWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKSEAVAQLWG 250
              P              LW+F+ + LL+   N   I WE  + G F+    + VA+ WG
Sbjct: 295 ILGPTSSRLANPGSGQIQLWQFLLE-LLSDSSNSSCITWEG-TNGEFKMTDPDEVARRWG 352

Query: 251 KKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKF 288
           ++K+  +M Y+KLSRA+RYYY + I+ +V G+R  YKF
Sbjct: 353 ERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKF 390


>gi|209954797 ets-related isoform 3 [Homo sapiens]
          Length = 486

 Score = 89.0 bits (219), Expect = 5e-18
 Identities = 73/278 (26%), Positives = 118/278 (42%), Gaps = 54/278 (19%)

Query: 47  PQYWTKYQVWEWLQHLLDTNQL-DANCIPFQEFDINGEHLCSMSLQEFTRAAGTAG-QLL 104
           P  W+   V +WL+  +    L D N + FQ  D  G+ LC M+  +F R   +    +L
Sbjct: 138 PTLWSTDHVRQWLEWAVKEYGLPDVNILLFQNID--GKELCKMTKDDFQRLTPSYNADIL 195

Query: 105 YSNLQHLKWNGQCSSDLFQSTHNVIVKTEQTEPSIMNTWKDENYLYDTNYGSTVDLL-DS 163
            S+L +L+      + L   T + + K  Q  P +M+           N G    +  ++
Sbjct: 196 LSHLHYLR-----ETPLPHLTSDDVDKALQNSPRLMHA---------RNTGGAAFIFPNT 241

Query: 164 KTFCRAQISMTTTSHLP----------------------------VAESPDMKKEQDP-- 193
             +  A   +TT   LP                            V ++ D + + DP  
Sbjct: 242 SVYPEATQRITTRPDLPYEPPRRSAWTGHGHPTPQSKAAQPSPSTVPKTEDQRPQLDPYQ 301

Query: 194 ---PAKCHTKKHNPRGTHLWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKSEAVAQLWG 250
              P              LW+F+ + LL+   N   I WE  + G F+    + VA+ WG
Sbjct: 302 ILGPTSSRLANPGSGQIQLWQFLLE-LLSDSSNSSCITWEG-TNGEFKMTDPDEVARRWG 359

Query: 251 KKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKF 288
           ++K+  +M Y+KLSRA+RYYY + I+ +V G+R  YKF
Sbjct: 360 ERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKF 397


>gi|6912580 SAM pointed domain containing ets transcription factor
           [Homo sapiens]
          Length = 335

 Score = 86.3 bits (212), Expect = 3e-17
 Identities = 59/243 (24%), Positives = 107/243 (44%), Gaps = 59/243 (24%)

Query: 47  PQYWTKYQVWEWLQHLLDTNQLDANCIPFQEFDINGEHLCSMSLQEFTRAAGTAGQLLYS 106
           P  W+   V +WL       +L      FQE  + G+ LC+MS ++F + +   G +L++
Sbjct: 147 PMDWSPSNVQKWLLWTEHQYRLPPMGKAFQE--LAGKELCAMSEEQFRQRSPLGGDVLHA 204

Query: 107 NLQHLKWNGQCSSDLFQSTHNVIVKTEQTEPSIMNTWKDENYLYDTNYGSTVDLLDSKTF 166
           +L                                + WK   ++ +      +        
Sbjct: 205 HL--------------------------------DIWKSAAWMKERTSPGAI-------- 224

Query: 167 CRAQISMTTTSHLPVAESPDMKKEQDPPAKCHTKKHNPRGTHLWEFIRDILLNPDKNPGL 226
                      H   + S +   + +  + C     + +  HLW+F++++LL P      
Sbjct: 225 -----------HYCASTSEESWTDSEVDSSC-----SGQPIHLWQFLKELLLKPHSYGRF 268

Query: 227 IKWEDRSEGVFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVD-GRRLV 285
           I+W ++ +G+F+   S  VA+LWG +KN  +M Y+KLSR++R YYK+ I+ + D  +RLV
Sbjct: 269 IRWLNKEKGIFKIEDSAQVARLWGIRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLV 328

Query: 286 YKF 288
           Y+F
Sbjct: 329 YQF 331


>gi|34452721 GA binding protein transcription factor, alpha subunit
           [Homo sapiens]
          Length = 454

 Score = 85.5 bits (210), Expect = 5e-17
 Identities = 66/242 (27%), Positives = 111/242 (45%), Gaps = 28/242 (11%)

Query: 47  PQYWTKYQVWEWLQHLLDTNQLDANCIPFQEFDINGEHLCSMSLQEFTRAAGTAGQLLYS 106
           P  W+  QV  W+  ++   +     I     +I+G  LCS++ ++F +     G++L+S
Sbjct: 186 PIQWSTDQVLHWVVWVM--KEFSMTDIDLTTLNISGRELCSLNQEDFFQRV-PRGEILWS 242

Query: 107 NLQHLKWNGQCSSDLFQSTHNVIVKTEQTEPSIMNTWKDENYLYDTNYGSTVDLLDSKTF 166
           +L+ L+     S +      N IV  +Q    I  +                  + S T 
Sbjct: 243 HLELLRKYVLASQE---QQMNEIVTIDQPVQIIPAS------------------VQSATP 281

Query: 167 CRAQISMTTTSHLPVAESPDMKKEQDPPAKCHTKKHNPRGTHLWEFIRDILLNPDKNPGL 226
              ++  ++     V  +P +  E        T  +      LW+F+ ++L + D     
Sbjct: 282 TTIKVINSSAKAAKVQRAPRISGEDRSSPGNRTGNNGQ--IQLWQFLLELLTDKDARD-C 338

Query: 227 IKWEDRSEGVFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVY 286
           I W    EG F+  + E VAQ WG++KN  +M YEKLSRA+RYYY  +++ +V G+R VY
Sbjct: 339 ISWVG-DEGEFKLNQPELVAQKWGQRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVY 397

Query: 287 KF 288
           KF
Sbjct: 398 KF 399


>gi|44955921 ELK3 protein [Homo sapiens]
          Length = 407

 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 39/80 (48%), Positives = 60/80 (75%), Gaps = 2/80 (2%)

Query: 209 LWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMR 268
           LW+F+  +LL+  K+  LI W   ++G F+ LK+E VA+LWG +KN ++M Y+KLSRA+R
Sbjct: 7   LWQFLLQLLLD-QKHEHLICWTS-NDGEFKLLKAEEVAKLWGLRKNKTNMNYDKLSRALR 64

Query: 269 YYYKREILERVDGRRLVYKF 288
           YYY + I+++V G++ VYKF
Sbjct: 65  YYYDKNIIKKVIGQKFVYKF 84


>gi|166362732 ELK1 protein [Homo sapiens]
          Length = 428

 Score = 83.6 bits (205), Expect = 2e-16
 Identities = 37/80 (46%), Positives = 54/80 (67%), Gaps = 1/80 (1%)

Query: 209 LWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMR 268
           LW+F+   LL    N  +I W  R  G F+ + +E VA+LWG +KN ++M Y+KLSRA+R
Sbjct: 7   LWQFLLQ-LLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKLSRALR 65

Query: 269 YYYKREILERVDGRRLVYKF 288
           YYY + I+ +V G++ VYKF
Sbjct: 66  YYYDKNIIRKVSGQKFVYKF 85


>gi|166362730 ELK1 protein [Homo sapiens]
          Length = 428

 Score = 83.6 bits (205), Expect = 2e-16
 Identities = 37/80 (46%), Positives = 54/80 (67%), Gaps = 1/80 (1%)

Query: 209 LWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMR 268
           LW+F+   LL    N  +I W  R  G F+ + +E VA+LWG +KN ++M Y+KLSRA+R
Sbjct: 7   LWQFLLQ-LLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKLSRALR 65

Query: 269 YYYKREILERVDGRRLVYKF 288
           YYY + I+ +V G++ VYKF
Sbjct: 66  YYYDKNIIRKVSGQKFVYKF 85


>gi|11496882 ELK4 protein isoform b [Homo sapiens]
          Length = 405

 Score = 82.0 bits (201), Expect = 6e-16
 Identities = 37/80 (46%), Positives = 59/80 (73%), Gaps = 2/80 (2%)

Query: 209 LWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMR 268
           LW+F+  +L  P +N  +I W   ++G F+ L++E VA+LWG +KN  +M Y+KLSRA+R
Sbjct: 7   LWQFLLQLLQKP-QNKHMICWTS-NDGQFKLLQAEEVARLWGIRKNKPNMNYDKLSRALR 64

Query: 269 YYYKREILERVDGRRLVYKF 288
           YYY + I+++V+G++ VYKF
Sbjct: 65  YYYVKNIIKKVNGQKFVYKF 84


>gi|41872448 ELK4 protein isoform a [Homo sapiens]
          Length = 431

 Score = 82.0 bits (201), Expect = 6e-16
 Identities = 37/80 (46%), Positives = 59/80 (73%), Gaps = 2/80 (2%)

Query: 209 LWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMR 268
           LW+F+  +L  P +N  +I W   ++G F+ L++E VA+LWG +KN  +M Y+KLSRA+R
Sbjct: 7   LWQFLLQLLQKP-QNKHMICWTS-NDGQFKLLQAEEVARLWGIRKNKPNMNYDKLSRALR 64

Query: 269 YYYKREILERVDGRRLVYKF 288
           YYY + I+++V+G++ VYKF
Sbjct: 65  YYYVKNIIKKVNGQKFVYKF 84


>gi|4503611 ets variant 6 [Homo sapiens]
          Length = 452

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 34/82 (41%), Positives = 56/82 (68%), Gaps = 1/82 (1%)

Query: 209 LWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMR 268
           LW+++   LL+  +    I+WED+   +FR +    +A+LWG  KN ++MTYEK+SRA+R
Sbjct: 341 LWDYVYQ-LLSDSRYENFIRWEDKESKIFRIVDPNGLARLWGNHKNRTNMTYEKMSRALR 399

Query: 269 YYYKREILERVDGRRLVYKFGK 290
           +YYK  I+ +  G+RL+++F K
Sbjct: 400 HYYKLNIIRKEPGQRLLFRFMK 421



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 19/67 (28%), Positives = 36/67 (53%), Gaps = 2/67 (2%)

Query: 45  IHPQYWTKYQVWEWLQHLLDTNQLDANCIPFQEFDINGEHLCSMSLQEFTRAAGTAGQLL 104
           + P YW++  V +WL+     N+     I    F++NG+ L  ++ ++F   +  +G +L
Sbjct: 56  LQPIYWSRDDVAQWLKWA--ENEFSLRPIDSNTFEMNGKALLLLTKEDFRYRSPHSGDVL 113

Query: 105 YSNLQHL 111
           Y  LQH+
Sbjct: 114 YELLQHI 120


>gi|153791178 ets variant gene 2 [Homo sapiens]
          Length = 342

 Score = 78.2 bits (191), Expect = 8e-15
 Identities = 43/115 (37%), Positives = 65/115 (56%), Gaps = 5/115 (4%)

Query: 176 TSHLPVAESPDMKKEQDPPAKCHTKKHNPRGT-HLWEFIRDILLNPDKNPGLIKWEDRSE 234
           +S L V   P  + ++   A+C   K N RG   LW+F+ + LL+       I+W   S 
Sbjct: 211 SSALTVCSEPSPQSDRASLARC--PKTNHRGPIQLWQFLLE-LLHDGARSSCIRWTGNSR 267

Query: 235 GVFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKFG 289
             F+    + VA+LWG++K    M YEKLSR +RYYY+R+I+ +  GR+  Y+FG
Sbjct: 268 E-FQLCDPKEVARLWGERKRKPGMNYEKLSRGLRYYYRRDIVRKSGGRKYTYRFG 321


>gi|4758316 ets variant gene 5 (ets-related molecule) [Homo sapiens]
          Length = 510

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 42/109 (38%), Positives = 65/109 (59%), Gaps = 3/109 (2%)

Query: 181 VAESPDMKKEQDPPAKCHTKKHNPRGT-HLWEFIRDILLNPDKNPGLIKWEDRSEGVFRF 239
           V E  + K +Q+P        +  RG+  LW+F+  +L +P  N   I W  R    F+ 
Sbjct: 341 VPERLEGKVKQEPTMYREGPPYQRRGSLQLWQFLVTLLDDP-ANAHFIAWTGRGME-FKL 398

Query: 240 LKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKF 288
           ++ E VA+ WG +KN  +M Y+KLSR++RYYY++ I+++V G R VYKF
Sbjct: 399 IEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF 447


>gi|253683437 ets variant gene 1 isoform f [Homo sapiens]
          Length = 374

 Score = 74.3 bits (181), Expect = 1e-13
 Identities = 42/109 (38%), Positives = 64/109 (58%), Gaps = 3/109 (2%)

Query: 181 VAESPDMKKEQDPPAKCHTKKHNPRGT-HLWEFIRDILLNPDKNPGLIKWEDRSEGVFRF 239
           V E  D   +Q+P        +  RG+  LW+F+  +L +P  N   I W  R    F+ 
Sbjct: 205 VPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPS-NSHFIAWTGRGME-FKL 262

Query: 240 LKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKF 288
           ++ E VA+ WG +KN  +M Y+KLSR++RYYY++ I+++V G R VYKF
Sbjct: 263 IEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF 311


>gi|253683435 ets variant gene 1 isoform e [Homo sapiens]
          Length = 419

 Score = 74.3 bits (181), Expect = 1e-13
 Identities = 42/109 (38%), Positives = 64/109 (58%), Gaps = 3/109 (2%)

Query: 181 VAESPDMKKEQDPPAKCHTKKHNPRGT-HLWEFIRDILLNPDKNPGLIKWEDRSEGVFRF 239
           V E  D   +Q+P        +  RG+  LW+F+  +L +P  N   I W  R    F+ 
Sbjct: 250 VPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPS-NSHFIAWTGRGME-FKL 307

Query: 240 LKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKF 288
           ++ E VA+ WG +KN  +M Y+KLSR++RYYY++ I+++V G R VYKF
Sbjct: 308 IEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF 356


>gi|253683433 ets variant gene 1 isoform d [Homo sapiens]
          Length = 437

 Score = 74.3 bits (181), Expect = 1e-13
 Identities = 42/109 (38%), Positives = 64/109 (58%), Gaps = 3/109 (2%)

Query: 181 VAESPDMKKEQDPPAKCHTKKHNPRGT-HLWEFIRDILLNPDKNPGLIKWEDRSEGVFRF 239
           V E  D   +Q+P        +  RG+  LW+F+  +L +P  N   I W  R    F+ 
Sbjct: 268 VPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPS-NSHFIAWTGRGME-FKL 325

Query: 240 LKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKF 288
           ++ E VA+ WG +KN  +M Y+KLSR++RYYY++ I+++V G R VYKF
Sbjct: 326 IEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF 374


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,933,889
Number of Sequences: 37866
Number of extensions: 588890
Number of successful extensions: 1294
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1217
Number of HSP's gapped (non-prelim): 79
length of query: 300
length of database: 18,247,518
effective HSP length: 102
effective length of query: 198
effective length of database: 14,385,186
effective search space: 2848266828
effective search space used: 2848266828
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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