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Search of human proteins with 26051210
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|26051210 calcium/calmodulin-dependent protein kinase II beta
isoform 4 [Homo sapiens]
(517 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|26051210 calcium/calmodulin-dependent protein kinase II beta ... 1058 0.0
gi|26051208 calcium/calmodulin-dependent protein kinase II beta ... 1053 0.0
gi|26051206 calcium/calmodulin-dependent protein kinase II beta ... 1044 0.0
gi|26051212 calcium/calmodulin-dependent protein kinase II beta ... 1012 0.0
gi|26051216 calcium/calmodulin-dependent protein kinase II beta ... 956 0.0
gi|26667199 calcium/calmodulin-dependent protein kinase II gamma... 928 0.0
gi|26667211 calcium/calmodulin-dependent protein kinase II gamma... 921 0.0
gi|26051214 calcium/calmodulin-dependent protein kinase II beta ... 915 0.0
gi|26667203 calcium/calmodulin-dependent protein kinase II gamma... 911 0.0
gi|26667191 calcium/calmodulin-dependent protein kinase II gamma... 908 0.0
gi|26667196 calcium/calmodulin-dependent protein kinase II gamma... 904 0.0
gi|212549753 calcium/calmodulin-dependent protein kinase II delt... 890 0.0
gi|212549756 calcium/calmodulin-dependent protein kinase II delt... 867 0.0
gi|26667183 calcium/calmodulin-dependent protein kinase II delta... 862 0.0
gi|26667186 calcium/calmodulin-dependent protein kinase II delta... 862 0.0
gi|26667180 calcium/calmodulin-dependent protein kinase II delta... 862 0.0
gi|26667189 calcium/calmodulin-dependent protein kinase II delta... 862 0.0
gi|25952114 calcium/calmodulin-dependent protein kinase II alpha... 840 0.0
gi|25952118 calcium/calmodulin-dependent protein kinase II alpha... 835 0.0
gi|26051204 calcium/calmodulin-dependent protein kinase II beta ... 768 0.0
gi|26051218 calcium/calmodulin-dependent protein kinase II beta ... 690 0.0
gi|186700629 calcium/calmodulin-dependent serine protein kinase ... 276 4e-74
gi|186700627 calcium/calmodulin-dependent serine protein kinase ... 276 4e-74
gi|186972120 calcium/calmodulin-dependent serine protein kinase ... 276 4e-74
gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo... 239 3e-63
gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo ... 238 8e-63
gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor... 237 2e-62
gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo... 228 8e-60
gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens] 225 9e-59
gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens] 225 9e-59
>gi|26051210 calcium/calmodulin-dependent protein kinase II beta
isoform 4 [Homo sapiens]
Length = 517
Score = 1058 bits (2736), Expect = 0.0
Identities = 517/517 (100%), Positives = 517/517 (100%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVIH 360
KGAILTTMLATRNFSAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVIH
Sbjct: 301 KGAILTTMLATRNFSAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVIH 360
Query: 361 NPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFE 420
NPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFE
Sbjct: 361 NPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFE 420
Query: 421 PEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQ 480
PEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQ
Sbjct: 421 PEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQ 480
Query: 481 GRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 517
GRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ
Sbjct: 481 GRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 517
>gi|26051208 calcium/calmodulin-dependent protein kinase II beta
isoform 3 [Homo sapiens]
Length = 518
Score = 1053 bits (2724), Expect = 0.0
Identities = 517/518 (99%), Positives = 517/518 (99%), Gaps = 1/518 (0%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFS-AKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVI 359
KGAILTTMLATRNFS AKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVI
Sbjct: 301 KGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVI 360
Query: 360 HNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSF 419
HNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSF
Sbjct: 361 HNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSF 420
Query: 420 EPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 479
EPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG
Sbjct: 421 EPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 480
Query: 480 QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 517
QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ
Sbjct: 481 QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 518
>gi|26051206 calcium/calmodulin-dependent protein kinase II beta
isoform 2 [Homo sapiens]
Length = 542
Score = 1044 bits (2700), Expect = 0.0
Identities = 517/542 (95%), Positives = 517/542 (95%), Gaps = 25/542 (4%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFS-------------------------AKSLLNKKADGVKPQTNSTK 335
KGAILTTMLATRNFS AKSLLNKKADGVKPQTNSTK
Sbjct: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK 360
Query: 336 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ 395
NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ
Sbjct: 361 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ 420
Query: 396 LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN 455
LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN
Sbjct: 421 LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN 480
Query: 456 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 515
PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP
Sbjct: 481 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 540
Query: 516 LQ 517
LQ
Sbjct: 541 LQ 542
>gi|26051212 calcium/calmodulin-dependent protein kinase II beta
isoform 5 [Homo sapiens]
Length = 503
Score = 1012 bits (2617), Expect = 0.0
Identities = 502/518 (96%), Positives = 502/518 (96%), Gaps = 16/518 (3%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFS-AKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVI 359
KGAILTTMLATRNFS AKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAAL
Sbjct: 301 KGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAAL------- 353
Query: 360 HNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSF 419
ESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSF
Sbjct: 354 --------ESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSF 405
Query: 420 EPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 479
EPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG
Sbjct: 406 EPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 465
Query: 480 QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 517
QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ
Sbjct: 466 QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 503
>gi|26051216 calcium/calmodulin-dependent protein kinase II beta
isoform 7 [Homo sapiens]
Length = 479
Score = 956 bits (2471), Expect = 0.0
Identities = 477/518 (92%), Positives = 478/518 (92%), Gaps = 40/518 (7%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSA-KSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVI 359
KGAILTTMLATRNFSA KSLLNKKAD
Sbjct: 301 KGAILTTMLATRNFSAAKSLLNKKAD---------------------------------- 326
Query: 360 HNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSF 419
G+KESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSF
Sbjct: 327 -----GVKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSF 381
Query: 420 EPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 479
EPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG
Sbjct: 382 EPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 441
Query: 480 QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 517
QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ
Sbjct: 442 QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 479
>gi|26667199 calcium/calmodulin-dependent protein kinase II gamma
isoform 3 [Homo sapiens]
Length = 518
Score = 928 bits (2399), Expect = 0.0
Identities = 455/519 (87%), Positives = 481/519 (92%), Gaps = 3/519 (0%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
Query: 301 KGAILTTMLATRNFS-AKSLLNKKAD-GVKPQTNSTKNSAAATSPKGTLPPAALEPQTTV 358
KGAILTTML +RNFS AKSLLNKK+D GVKPQ+N+ KNS + + + A+EPQTTV
Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNN-KNSLVSPAQEPAPLQTAMEPQTTV 359
Query: 359 IHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTS 418
+HN DGIK S++S NTT EDED K RKQEIIK TEQLIEA+NNGDFEAY KICDPGLTS
Sbjct: 360 VHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTS 419
Query: 419 FEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYID 478
FEPEALGNLVEGMDFH+FYFENLL+KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYID
Sbjct: 420 FEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYID 479
Query: 479 GQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 517
GQGRPRTSQSEETRVWHRRDGKW NVH+HCSGAP APLQ
Sbjct: 480 GQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 518
>gi|26667211 calcium/calmodulin-dependent protein kinase II gamma
isoform 6 [Homo sapiens]
Length = 504
Score = 921 bits (2381), Expect = 0.0
Identities = 455/519 (87%), Positives = 477/519 (91%), Gaps = 17/519 (3%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
Query: 301 KGAILTTMLATRNFS-AKSLLNKKAD-GVKPQTNSTKNSAAATSPKGTLPPAALEPQTTV 358
KGAILTTML +RNFS AKSLLNKK+D GVKPQ+N+ KNS LEPQTTV
Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNN-KNS--------------LEPQTTV 345
Query: 359 IHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTS 418
+HN DGIK S++S NTT EDED K RKQEIIK TEQLIEA+NNGDFEAY KICDPGLTS
Sbjct: 346 VHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTS 405
Query: 419 FEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYID 478
FEPEALGNLVEGMDFH+FYFENLL+KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYID
Sbjct: 406 FEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYID 465
Query: 479 GQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 517
GQGRPRTSQSEETRVWHRRDGKW NVH+HCSGAP APLQ
Sbjct: 466 GQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 504
>gi|26051214 calcium/calmodulin-dependent protein kinase II beta
isoform 6 [Homo sapiens]
Length = 492
Score = 915 bits (2365), Expect = 0.0
Identities = 467/542 (86%), Positives = 467/542 (86%), Gaps = 75/542 (13%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFS-------------------------AKSLLNKKADGVKPQTNSTK 335
KGAILTTMLATRNFS AKSLLNKKADGVK
Sbjct: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVK------- 353
Query: 336 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ 395
EPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ
Sbjct: 354 -----------------EPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ 396
Query: 396 LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN 455
LIEAVNNGDFEAYA FYFENLLAKNSKPIHTTILN
Sbjct: 397 LIEAVNNGDFEAYA--------------------------FYFENLLAKNSKPIHTTILN 430
Query: 456 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 515
PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP
Sbjct: 431 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 490
Query: 516 LQ 517
LQ
Sbjct: 491 LQ 492
>gi|26667203 calcium/calmodulin-dependent protein kinase II gamma
isoform 1 [Homo sapiens]
Length = 556
Score = 911 bits (2354), Expect = 0.0
Identities = 456/557 (81%), Positives = 482/557 (86%), Gaps = 41/557 (7%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
Query: 301 KGAILTTMLATRNFS-AKSLLNKKAD-GVKPQTNSTKNSAAATSPKGTLPPAALEPQTTV 358
KGAILTTML +RNFS AKSLLNKK+D GVKPQ+N+ KNS + + + A+EPQTTV
Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNN-KNSLVSPAQEPAPLQTAMEPQTTV 359
Query: 359 IHNPVDGIKESSDSANTTIEDEDAKA---------------------------------- 384
+HN DGIK S++S NTT EDED KA
Sbjct: 360 VHNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSVPEGRSSRDRTAPSAGMQPQPSLC 419
Query: 385 ----RKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFEN 440
RKQEIIK TEQLIEA+NNGDFEAY KICDPGLTSFEPEALGNLVEGMDFH+FYFEN
Sbjct: 420 SSAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFEN 479
Query: 441 LLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGK 500
LL+KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGK
Sbjct: 480 LLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGK 539
Query: 501 WQNVHFHCSGAPVAPLQ 517
W NVH+HCSGAP APLQ
Sbjct: 540 WLNVHYHCSGAPAAPLQ 556
>gi|26667191 calcium/calmodulin-dependent protein kinase II gamma
isoform 4 [Homo sapiens]
Length = 495
Score = 908 bits (2346), Expect = 0.0
Identities = 446/518 (86%), Positives = 466/518 (89%), Gaps = 24/518 (4%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
Query: 301 KGAILTTMLATRNFS-AKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVI 359
KGAILTTML +RNFS AKSLLNKK+DG EPQTTV+
Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDG-----------------------GVKEPQTTVV 337
Query: 360 HNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSF 419
HN DGIK S++S NTT EDED K RKQEIIK TEQLIEA+NNGDFEAY KICDPGLTSF
Sbjct: 338 HNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSF 397
Query: 420 EPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 479
EPEALGNLVEGMDFH+FYFENLL+KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG
Sbjct: 398 EPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 457
Query: 480 QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 517
QGRPRTSQSEETRVWHRRDGKW NVH+HCSGAP APLQ
Sbjct: 458 QGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 495
>gi|26667196 calcium/calmodulin-dependent protein kinase II gamma
isoform 2 [Homo sapiens]
Length = 527
Score = 904 bits (2336), Expect = 0.0
Identities = 449/540 (83%), Positives = 473/540 (87%), Gaps = 36/540 (6%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
Query: 301 KGAILTTMLATRNFS----------------------AKSLLNKKAD-GVKPQTNSTKNS 337
KGAILTTML +RNFS AKSLLNKK+D GVK + +S+
Sbjct: 301 KGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKKRKSSSS-- 358
Query: 338 AAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLI 397
+EPQTTV+HN DGIK S++S NTT EDED K RKQEIIK TEQLI
Sbjct: 359 -----------VHLMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLI 407
Query: 398 EAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPH 457
EA+NNGDFEAY KICDPGLTSFEPEALGNLVEGMDFH+FYFENLL+KNSKPIHTTILNPH
Sbjct: 408 EAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPH 467
Query: 458 VHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 517
VHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW NVH+HCSGAP APLQ
Sbjct: 468 VHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 527
>gi|212549753 calcium/calmodulin-dependent protein kinase II delta
isoform 5 [Homo sapiens]
Length = 492
Score = 890 bits (2301), Expect = 0.0
Identities = 434/517 (83%), Positives = 465/517 (89%), Gaps = 25/517 (4%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVIH 360
KGAILTTMLATRNFSA L KK DGVK EPQTTVIH
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKPDGVK------------------------EPQTTVIH 336
Query: 361 NPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFE 420
NP DG KES++S+NTTIEDED KARKQEIIK TEQLIEA+NNGDFEAY KICDPGLT+FE
Sbjct: 337 NP-DGNKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFE 395
Query: 421 PEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQ 480
PEALGNLVEGMDFHRFYFEN L+K++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG
Sbjct: 396 PEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGS 455
Query: 481 GRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 517
G P+T QSEETRVWHRRDGKWQNVHFH SG+P P++
Sbjct: 456 GMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 492
>gi|212549756 calcium/calmodulin-dependent protein kinase II delta
isoform 4 [Homo sapiens]
Length = 489
Score = 867 bits (2241), Expect = 0.0
Identities = 422/517 (81%), Positives = 457/517 (88%), Gaps = 28/517 (5%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVIH 360
KGAILTTMLATRNFSA L KK DGVK + +S+
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKKRKSSSSVQ----------------------- 337
Query: 361 NPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFE 420
+ ES++S+NTTIEDED KARKQEIIK TEQLIEA+NNGDFEAY KICDPGLT+FE
Sbjct: 338 -----MMESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFE 392
Query: 421 PEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQ 480
PEALGNLVEGMDFHRFYFEN L+K++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG
Sbjct: 393 PEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGS 452
Query: 481 GRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 517
G P+T QSEETRVWHRRDGKWQNVHFH SG+P P++
Sbjct: 453 GMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 489
>gi|26667183 calcium/calmodulin-dependent protein kinase II delta
isoform 1 [Homo sapiens]
Length = 478
Score = 862 bits (2228), Expect = 0.0
Identities = 422/518 (81%), Positives = 454/518 (87%), Gaps = 41/518 (7%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSA-KSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVI 359
KGAILTTMLATRNFSA KSLL K
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKP------------------------------------ 324
Query: 360 HNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSF 419
DG+KES++S+NTTIEDED KARKQEIIK TEQLIEA+NNGDFEAY KICDPGLT+F
Sbjct: 325 ----DGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAF 380
Query: 420 EPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 479
EPEALGNLVEGMDFHRFYFEN L+K++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG
Sbjct: 381 EPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDG 440
Query: 480 QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 517
G P+T QSEETRVWHRRDGKWQNVHFH SG+P P++
Sbjct: 441 SGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 478
>gi|26667186 calcium/calmodulin-dependent protein kinase II delta
isoform 1 [Homo sapiens]
Length = 478
Score = 862 bits (2228), Expect = 0.0
Identities = 422/518 (81%), Positives = 454/518 (87%), Gaps = 41/518 (7%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSA-KSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVI 359
KGAILTTMLATRNFSA KSLL K
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKP------------------------------------ 324
Query: 360 HNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSF 419
DG+KES++S+NTTIEDED KARKQEIIK TEQLIEA+NNGDFEAY KICDPGLT+F
Sbjct: 325 ----DGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAF 380
Query: 420 EPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 479
EPEALGNLVEGMDFHRFYFEN L+K++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG
Sbjct: 381 EPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDG 440
Query: 480 QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 517
G P+T QSEETRVWHRRDGKWQNVHFH SG+P P++
Sbjct: 441 SGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 478
>gi|26667180 calcium/calmodulin-dependent protein kinase II delta
isoform 3 [Homo sapiens]
Length = 499
Score = 862 bits (2228), Expect = 0.0
Identities = 422/518 (81%), Positives = 454/518 (87%), Gaps = 41/518 (7%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSA-KSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVI 359
KGAILTTMLATRNFSA KSLL K
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKP------------------------------------ 324
Query: 360 HNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSF 419
DG+KES++S+NTTIEDED KARKQEIIK TEQLIEA+NNGDFEAY KICDPGLT+F
Sbjct: 325 ----DGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAF 380
Query: 420 EPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 479
EPEALGNLVEGMDFHRFYFEN L+K++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG
Sbjct: 381 EPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDG 440
Query: 480 QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 517
G P+T QSEETRVWHRRDGKWQNVHFH SG+P P++
Sbjct: 441 SGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 478
>gi|26667189 calcium/calmodulin-dependent protein kinase II delta
isoform 2 [Homo sapiens]
Length = 478
Score = 862 bits (2227), Expect = 0.0
Identities = 422/517 (81%), Positives = 453/517 (87%), Gaps = 41/517 (7%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSA-KSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVI 359
KGAILTTMLATRNFSA KSLL K
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKP------------------------------------ 324
Query: 360 HNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSF 419
DG+KES++S+NTTIEDED KARKQEIIK TEQLIEA+NNGDFEAY KICDPGLT+F
Sbjct: 325 ----DGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAF 380
Query: 420 EPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 479
EPEALGNLVEGMDFHRFYFEN L+K++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG
Sbjct: 381 EPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDG 440
Query: 480 QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPL 516
G P+T QSEETRVWHRRDGKWQNVHFH SG+P P+
Sbjct: 441 SGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPI 477
>gi|25952114 calcium/calmodulin-dependent protein kinase II alpha
isoform 1 [Homo sapiens]
Length = 489
Score = 840 bits (2170), Expect = 0.0
Identities = 408/510 (80%), Positives = 450/510 (88%), Gaps = 29/510 (5%)
Query: 4 TVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREAR 63
T+TCTRFT+EYQL+E++GKGAFSVVRRCVK+ G EYAAKIINTKKLSARDHQKLEREAR
Sbjct: 3 TITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREAR 62
Query: 64 ICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 123
ICRLLKH NIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCIQQILEA
Sbjct: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 122
Query: 124 VLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSP 183
VLHCHQMGVVHRDLKPENLLLASK KGAAVKLADFGLAIEV+G+QQAWFGFAGTPGYLSP
Sbjct: 123 VLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSP 182
Query: 184 EVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 243
EVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDTVTP
Sbjct: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTP 242
Query: 244 EAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGA 303
EAK+LIN+MLTINP+KRITA EALKHPW+ RSTVAS MHRQETV+CLKKFNARRKLKGA
Sbjct: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGA 302
Query: 304 ILTTMLATRNFS-AKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVIHNP 362
ILTTMLATRNFS KS NKK+DGVK + +S+
Sbjct: 303 ILTTMLATRNFSGGKSGGNKKSDGVKKRKSSSSVQ------------------------- 337
Query: 363 VDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPE 422
+ ESS+S NTTIEDED K RKQEIIK TEQLIEA++NGDFE+Y K+CDPG+T+FEPE
Sbjct: 338 ---LMESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPE 394
Query: 423 ALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGR 482
ALGNLVEG+DFHRFYFENL ++NSKP+HTTILNPH+H++G+++ACIAYIR+TQY+D G
Sbjct: 395 ALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGI 454
Query: 483 PRTSQSEETRVWHRRDGKWQNVHFHCSGAP 512
PRT+QSEETRVWHRRDGKWQ VHFH SGAP
Sbjct: 455 PRTAQSEETRVWHRRDGKWQIVHFHRSGAP 484
>gi|25952118 calcium/calmodulin-dependent protein kinase II alpha
isoform 2 [Homo sapiens]
Length = 478
Score = 835 bits (2156), Expect = 0.0
Identities = 407/510 (79%), Positives = 445/510 (87%), Gaps = 40/510 (7%)
Query: 4 TVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREAR 63
T+TCTRFT+EYQL+E++GKGAFSVVRRCVK+ G EYAAKIINTKKLSARDHQKLEREAR
Sbjct: 3 TITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREAR 62
Query: 64 ICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 123
ICRLLKH NIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCIQQILEA
Sbjct: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 122
Query: 124 VLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSP 183
VLHCHQMGVVHRDLKPENLLLASK KGAAVKLADFGLAIEV+G+QQAWFGFAGTPGYLSP
Sbjct: 123 VLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSP 182
Query: 184 EVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 243
EVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDTVTP
Sbjct: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTP 242
Query: 244 EAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGA 303
EAK+LIN+MLTINP+KRITA EALKHPW+ RSTVAS MHRQETV+CLKKFNARRKLKGA
Sbjct: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGA 302
Query: 304 ILTTMLATRNFS-AKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVIHNP 362
ILTTMLATRNFS KS NKK+DGVK
Sbjct: 303 ILTTMLATRNFSGGKSGGNKKSDGVK---------------------------------- 328
Query: 363 VDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPE 422
ESS+S NTTIEDED K RKQEIIK TEQLIEA++NGDFE+Y K+CDPG+T+FEPE
Sbjct: 329 -----ESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPE 383
Query: 423 ALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGR 482
ALGNLVEG+DFHRFYFENL ++NSKP+HTTILNPH+H++G+++ACIAYIR+TQY+D G
Sbjct: 384 ALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGI 443
Query: 483 PRTSQSEETRVWHRRDGKWQNVHFHCSGAP 512
PRT+QSEETRVWHRRDGKWQ VHFH SGAP
Sbjct: 444 PRTAQSEETRVWHRRDGKWQIVHFHRSGAP 473
>gi|26051204 calcium/calmodulin-dependent protein kinase II beta
isoform 1 [Homo sapiens]
Length = 666
Score = 768 bits (1984), Expect = 0.0
Identities = 392/447 (87%), Positives = 398/447 (89%), Gaps = 31/447 (6%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFS-------------------------AKSLLNKKADGVKPQTNSTK 335
KGAILTTMLATRNFS AKSLLNKKADGVKPQTNSTK
Sbjct: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK 360
Query: 336 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKA-RKQEIIKTTE 394
NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKA R +I+ +
Sbjct: 361 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKAPRVPDILSSVR 420
Query: 395 QLIEAVNNGDFEAYAKICDPGLTSFEP 421
+ +G EA + P F P
Sbjct: 421 R-----GSGAPEAEGPLPCPSPAPFSP 442
Score = 281 bits (720), Expect = 8e-76
Identities = 133/134 (99%), Positives = 134/134 (100%)
Query: 384 ARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLA 443
+RKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLA
Sbjct: 533 SRKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLA 592
Query: 444 KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQN 503
KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQN
Sbjct: 593 KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQN 652
Query: 504 VHFHCSGAPVAPLQ 517
VHFHCSGAPVAPLQ
Sbjct: 653 VHFHCSGAPVAPLQ 666
>gi|26051218 calcium/calmodulin-dependent protein kinase II beta
isoform 8 [Homo sapiens]
Length = 449
Score = 690 bits (1780), Expect = 0.0
Identities = 364/517 (70%), Positives = 389/517 (75%), Gaps = 68/517 (13%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKEAYGKPVDIWACGVILYILLVGYP P WD
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYP-----------------------PFWD- 216
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
E ++ + Q + + A++ W +++++ T+ K+ A L
Sbjct: 217 ---EDQHKLYQQI------KAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEAL 267
Query: 301 KGAILTTMLATRNFSAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVIH 360
K + + + S+++++ K A KG +
Sbjct: 268 KHPWVC-----QRSTVASMMHRQET-----VECLKKFNARRKLKGAI------------- 304
Query: 361 NPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFE 420
T + + ARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFE
Sbjct: 305 ------------LTTMLATRNFSARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFE 352
Query: 421 PEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQ 480
PEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQ
Sbjct: 353 PEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQ 412
Query: 481 GRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 517
GRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ
Sbjct: 413 GRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 449
>gi|186700629 calcium/calmodulin-dependent serine protein kinase
isoform 3 [Homo sapiens]
Length = 897
Score = 276 bits (705), Expect = 4e-74
Identities = 143/306 (46%), Positives = 203/306 (66%), Gaps = 8/306 (2%)
Query: 10 FTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSAR---DHQKLEREARICR 66
F D Y+L E IGKG FSVVRRC+ TG ++A KI++ K ++ + L+REA IC
Sbjct: 8 FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67
Query: 67 LLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----YYSEADASHCIQQILE 122
+LKH +IV L ++ S +G Y+VF+ + G +L +IV R YSEA ASH ++QILE
Sbjct: 68 MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 123 AVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
A+ +CH ++HRD+KP +LLASK A VKL FG+AI++ G GTP +++
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 183 PEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVT 242
PEV+++E YGKPVD+W CGVIL+ILL G PF+ + +L++ I G Y +W ++
Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246
Query: 243 PEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKG 302
AK+L+ +ML ++PA+RIT +EAL HPW+ +R A +H ETVE L+KFNARRKLKG
Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306
Query: 303 AILTTM 308
A+L +
Sbjct: 307 AVLAAV 312
>gi|186700627 calcium/calmodulin-dependent serine protein kinase
isoform 2 [Homo sapiens]
Length = 898
Score = 276 bits (705), Expect = 4e-74
Identities = 143/306 (46%), Positives = 203/306 (66%), Gaps = 8/306 (2%)
Query: 10 FTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSAR---DHQKLEREARICR 66
F D Y+L E IGKG FSVVRRC+ TG ++A KI++ K ++ + L+REA IC
Sbjct: 8 FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67
Query: 67 LLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----YYSEADASHCIQQILE 122
+LKH +IV L ++ S +G Y+VF+ + G +L +IV R YSEA ASH ++QILE
Sbjct: 68 MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 123 AVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
A+ +CH ++HRD+KP +LLASK A VKL FG+AI++ G GTP +++
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 183 PEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVT 242
PEV+++E YGKPVD+W CGVIL+ILL G PF+ + +L++ I G Y +W ++
Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246
Query: 243 PEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKG 302
AK+L+ +ML ++PA+RIT +EAL HPW+ +R A +H ETVE L+KFNARRKLKG
Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306
Query: 303 AILTTM 308
A+L +
Sbjct: 307 AVLAAV 312
>gi|186972120 calcium/calmodulin-dependent serine protein kinase
isoform 1 [Homo sapiens]
Length = 921
Score = 276 bits (705), Expect = 4e-74
Identities = 143/306 (46%), Positives = 203/306 (66%), Gaps = 8/306 (2%)
Query: 10 FTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSAR---DHQKLEREARICR 66
F D Y+L E IGKG FSVVRRC+ TG ++A KI++ K ++ + L+REA IC
Sbjct: 8 FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67
Query: 67 LLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----YYSEADASHCIQQILE 122
+LKH +IV L ++ S +G Y+VF+ + G +L +IV R YSEA ASH ++QILE
Sbjct: 68 MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 123 AVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
A+ +CH ++HRD+KP +LLASK A VKL FG+AI++ G GTP +++
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 183 PEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVT 242
PEV+++E YGKPVD+W CGVIL+ILL G PF+ + +L++ I G Y +W ++
Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246
Query: 243 PEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKG 302
AK+L+ +ML ++PA+RIT +EAL HPW+ +R A +H ETVE L+KFNARRKLKG
Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306
Query: 303 AILTTM 308
A+L +
Sbjct: 307 AVLAAV 312
>gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform
2 [Homo sapiens]
Length = 385
Score = 239 bits (611), Expect = 3e-63
Identities = 133/339 (39%), Positives = 193/339 (56%), Gaps = 8/339 (2%)
Query: 14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNI 73
++ E +G GAFS V + TG +A K I K L ++ +E E + R +KH NI
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKE-SSIENEIAVLRKIKHENI 81
Query: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVV 133
V L D YLV LV+GGELF+ IV + +Y+E DAS I+Q+L+AV + H+MG+V
Sbjct: 82 VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141
Query: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGK 193
HRDLKPENLL S+ + + + ++DFGL+ +++G GTPGY++PEVL ++ Y K
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLS-KMEGKGDVMSTACGTPGYVAPEVLAQKPYSK 200
Query: 194 PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253
VD W+ GVI YILL GYPPF+DE+ KL++QI Y+F SP WD ++ AK+ I ++
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260
Query: 254 TINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLATRN 313
+P KR T +A +HPW+ + + +H + + K F A+ K + A T A
Sbjct: 261 EKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNF-AKSKWRQAFNAT--AVVR 317
Query: 314 FSAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAAL 352
K L D S +S + S K L P+ L
Sbjct: 318 HMRKLHLGSSLDS---SNASVSSSLSLASQKDCLAPSTL 353
>gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo
sapiens]
Length = 473
Score = 238 bits (608), Expect = 8e-63
Identities = 145/399 (36%), Positives = 224/399 (56%), Gaps = 33/399 (8%)
Query: 11 TDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKH 70
+D +++ ++G+GA S+V RC + T YA K++ D + + E + L H
Sbjct: 43 SDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLK----KTVDKKIVRTEIGVLLRLSH 98
Query: 71 SNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 130
NI++L + LV +LVTGGELF+ IV + YYSE DA+ ++QILEAV + H+
Sbjct: 99 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 158
Query: 131 GVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEA 190
G+VHRDLKPENLL A+ A +K+ADFGL+ ++ Q GTPGY +PE+LR A
Sbjct: 159 GIVHRDLKPENLLYATPAPDAPLKIADFGLS-KIVEHQVLMKTVCGTPGYCAPEILRGCA 217
Query: 191 YGKPVDIWACGVILYILLVGYPPFWDE--DQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL 248
YG VD+W+ G+I YILL G+ PF+DE DQ ++++I Y F SP WD V+ AK+L
Sbjct: 218 YGPEVDMWSVGIITYILLCGFEPFYDERGDQF-MFRRILNCEYYFISPWWDEVSLNAKDL 276
Query: 249 INQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTM 308
+ +++ ++P KR+T +AL+HPWV ++ A+ +H + L++FNARRKLK A+ +
Sbjct: 277 VRKLIVLDPKKRLTTFQALQHPWVTGKA--ANFVHMDTAQKKLQEFNARRKLKAAVKAVV 334
Query: 309 LATRNFSAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVIHNPVDGIKE 368
++R SA S+ + + S K + P+ ++ + +G K
Sbjct: 335 ASSRLGSA----------------SSSHGSIQESHKASRDPSPIQDGNEDMKAIPEGEKI 378
Query: 369 SSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEA 407
D A + K + E++K Q +E V D A
Sbjct: 379 QGDGAQAAV-----KGAQAELMKV--QALEKVKGADINA 410
>gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1
[Homo sapiens]
Length = 357
Score = 237 bits (604), Expect = 2e-62
Identities = 122/294 (41%), Positives = 179/294 (60%), Gaps = 3/294 (1%)
Query: 14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNI 73
++ E +G GAFS V + TG +A K I K L ++ +E E + R +KH NI
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKE-SSIENEIAVLRKIKHENI 81
Query: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVV 133
V L D YLV LV+GGELF+ IV + +Y+E DAS I+Q+L+AV + H+MG+V
Sbjct: 82 VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141
Query: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGK 193
HRDLKPENLL S+ + + + ++DFGL+ +++G GTPGY++PEVL ++ Y K
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLS-KMEGKGDVMSTACGTPGYVAPEVLAQKPYSK 200
Query: 194 PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253
VD W+ GVI YILL GYPPF+DE+ KL++QI Y+F SP WD ++ AK+ I ++
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260
Query: 254 TINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTT 307
+P KR T +A +HPW+ + + +H + + K F A+ K + A T
Sbjct: 261 EKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNF-AKSKWRQAFNAT 313
>gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo
sapiens]
Length = 476
Score = 228 bits (582), Expect = 8e-60
Identities = 137/357 (38%), Positives = 199/357 (55%), Gaps = 14/357 (3%)
Query: 8 TRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRL 67
T + E +G GAFS V + TG +A K I KK A LE E + +
Sbjct: 17 TNIRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCI--KKSPAFRDSSLENEIAVLKK 74
Query: 68 LKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHC 127
+KH NIV L D +YLV LV+GGELF+ I+ R Y+E DAS IQQ+L AV +
Sbjct: 75 IKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYL 134
Query: 128 HQMGVVHRDLKPENLLLASKCKGAAVKLADFGLA-IEVQGDQQAWFGFAGTPGYLSPEVL 186
H+ G+VHRDLKPENLL + + + + + DFGL+ +E G GTPGY++PEVL
Sbjct: 135 HENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNGIMST---ACGTPGYVAPEVL 191
Query: 187 RKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAK 246
++ Y K VD W+ GVI YILL GYPPF++E + KL+++IK G Y+F SP WD ++ AK
Sbjct: 192 AQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAK 251
Query: 247 NLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILT 306
+ I +L +P +R T +AL HPW+ + + ++ +++ K F A+ K + A
Sbjct: 252 DFICHLLEKDPNERYTCEKALSHPWIDGNTALHRDIYPSVSLQIQKNF-AKSKWRQAF-- 308
Query: 307 TMLATRNFSAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVIHNPV 363
A + K +N + GV+P+ +N T T P++ P+ T+ PV
Sbjct: 309 NAAAVVHHMRKLHMNLHSPGVRPE---VENRPPETQASETSRPSS--PEITITEAPV 360
>gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens]
Length = 765
Score = 225 bits (573), Expect = 9e-59
Identities = 131/363 (36%), Positives = 196/363 (53%), Gaps = 17/363 (4%)
Query: 12 DEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHS 71
++Y++ + IG G F+VV+ C+ TG E+A KII+ K ++H +E E I R +KH
Sbjct: 391 EKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHL-IENEVSILRRVKHP 449
Query: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 131
NI+ L + + +LV +LV GG+LF+ I + Y+E D S + + A+ + H +
Sbjct: 450 NIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLS 509
Query: 132 VVHRDLKPENLLLASKCKGA-AVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEA 190
+VHRD+KPENLL+ G ++KL DFGLA V+G + GTP Y++PE++ +
Sbjct: 510 IVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEG---PLYTVCGTPTYVAPEIIAETG 566
Query: 191 YGKPVDIWACGVILYILLVGYPPFWDED--QHKLYQQIKAGAYDFPSPEWDTVTPEAKNL 248
YG VDIWA GVI YILL G+PPF E+ Q L+ QI AG +FP+P WD +T AK L
Sbjct: 567 YGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKEL 626
Query: 249 INQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTM 308
I+QML +N R TA + L HPWV ++ + M + T + + FN + + T +
Sbjct: 627 ISQMLQVNVEARCTAGQILSHPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGV 686
Query: 309 LATRN---------FSAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVI 359
N F +K + G++P + S G PA P++
Sbjct: 687 SVIMNTALDKEGQIFCSKHCQDSGRPGMEP-ISPVPPSVEEIPVPGEAVPAPTPPESPTP 745
Query: 360 HNP 362
H P
Sbjct: 746 HPP 748
>gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens]
Length = 766
Score = 225 bits (573), Expect = 9e-59
Identities = 131/363 (36%), Positives = 196/363 (53%), Gaps = 17/363 (4%)
Query: 12 DEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHS 71
++Y++ + IG G F+VV+ C+ TG E+A KII+ K ++H +E E I R +KH
Sbjct: 392 EKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHL-IENEVSILRRVKHP 450
Query: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 131
NI+ L + + +LV +LV GG+LF+ I + Y+E D S + + A+ + H +
Sbjct: 451 NIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLS 510
Query: 132 VVHRDLKPENLLLASKCKGA-AVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEA 190
+VHRD+KPENLL+ G ++KL DFGLA V+G + GTP Y++PE++ +
Sbjct: 511 IVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEG---PLYTVCGTPTYVAPEIIAETG 567
Query: 191 YGKPVDIWACGVILYILLVGYPPFWDED--QHKLYQQIKAGAYDFPSPEWDTVTPEAKNL 248
YG VDIWA GVI YILL G+PPF E+ Q L+ QI AG +FP+P WD +T AK L
Sbjct: 568 YGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKEL 627
Query: 249 INQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTM 308
I+QML +N R TA + L HPWV ++ + M + T + + FN + + T +
Sbjct: 628 ISQMLQVNVEARCTAGQILSHPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGV 687
Query: 309 LATRN---------FSAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVI 359
N F +K + G++P + S G PA P++
Sbjct: 688 SVIMNTALDKEGQIFCSKHCQDSGRPGMEP-ISPVPPSVEEIPVPGEAVPAPTPPESPTP 746
Query: 360 HNP 362
H P
Sbjct: 747 HPP 749
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,142,207
Number of Sequences: 37866
Number of extensions: 905060
Number of successful extensions: 5249
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 567
Number of HSP's successfully gapped in prelim test: 235
Number of HSP's that attempted gapping in prelim test: 2871
Number of HSP's gapped (non-prelim): 1104
length of query: 517
length of database: 18,247,518
effective HSP length: 107
effective length of query: 410
effective length of database: 14,195,856
effective search space: 5820300960
effective search space used: 5820300960
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.