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Search of human proteins with 25141328
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|25141328 copine 7 isoform a [Homo sapiens]
(558 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|25141328 copine 7 isoform a [Homo sapiens] 1132 0.0
gi|7656993 copine 7 isoform b [Homo sapiens] 892 0.0
gi|18677733 copine IV [Homo sapiens] 783 0.0
gi|5174421 copine 6 [Homo sapiens] 723 0.0
gi|4503015 copine III [Homo sapiens] 601 e-172
gi|30181236 copine II [Homo sapiens] 597 e-171
gi|23397708 copine I isoform a [Homo sapiens] 546 e-155
gi|23397706 copine I isoform a [Homo sapiens] 546 e-155
gi|23397704 copine I isoform a [Homo sapiens] 546 e-155
gi|23397702 copine I isoform a [Homo sapiens] 546 e-155
gi|23397700 copine I isoform a [Homo sapiens] 546 e-155
gi|23397698 copine I isoform a [Homo sapiens] 546 e-155
gi|23397696 copine I isoform a [Homo sapiens] 546 e-155
gi|197333761 copine I isoform b [Homo sapiens] 546 e-155
gi|25121972 copine VIII [Homo sapiens] 508 e-144
gi|25141323 copine V [Homo sapiens] 489 e-138
gi|88703066 copine-like protein [Homo sapiens] 480 e-135
gi|47157322 protein kinase C, beta isoform 1 [Homo sapiens] 52 1e-06
gi|20127450 protein kinase C, beta isoform 2 [Homo sapiens] 52 1e-06
gi|13384594 protein kinase C, gamma [Homo sapiens] 50 7e-06
gi|28376627 synaptotagmin IX [Homo sapiens] 47 6e-05
gi|150170670 piccolo isoform 2 [Homo sapiens] 46 1e-04
gi|150378539 piccolo isoform 1 [Homo sapiens] 46 1e-04
gi|4506067 protein kinase C, alpha [Homo sapiens] 45 2e-04
gi|209447073 synaptotagmin I [Homo sapiens] 44 4e-04
gi|5032139 synaptotagmin I [Homo sapiens] 44 4e-04
gi|209447070 synaptotagmin I [Homo sapiens] 44 4e-04
gi|238550198 synaptotagmin III [Homo sapiens] 44 5e-04
gi|238550196 synaptotagmin III [Homo sapiens] 44 5e-04
gi|14150054 synaptotagmin III [Homo sapiens] 44 5e-04
>gi|25141328 copine 7 isoform a [Homo sapiens]
Length = 558
Score = 1132 bits (2927), Expect = 0.0
Identities = 558/558 (100%), Positives = 558/558 (100%)
Query: 1 MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVG 60
MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVG
Sbjct: 1 MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVG 60
Query: 61 RTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQI 120
RTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQI
Sbjct: 61 RTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQI 120
Query: 121 VAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLE 180
VAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLE
Sbjct: 121 VAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLE 180
Query: 181 LYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKHD 240
LYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKHD
Sbjct: 181 LYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKHD 240
Query: 241 FIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDYI 300
FIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDYI
Sbjct: 241 FIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDYI 300
Query: 301 MGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFSA 360
MGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFSA
Sbjct: 301 MGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFSA 360
Query: 361 LGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKV 420
LGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKV
Sbjct: 361 LGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKV 420
Query: 421 ARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTDM 480
ARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTDM
Sbjct: 421 ARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTDM 480
Query: 481 QVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHRGL 540
QVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHRGL
Sbjct: 481 QVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHRGL 540
Query: 541 PPRSLGVPAGEASPGCTP 558
PPRSLGVPAGEASPGCTP
Sbjct: 541 PPRSLGVPAGEASPGCTP 558
>gi|7656993 copine 7 isoform b [Homo sapiens]
Length = 633
Score = 892 bits (2304), Expect = 0.0
Identities = 440/440 (100%), Positives = 440/440 (100%)
Query: 119 QIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPF 178
QIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPF
Sbjct: 194 QIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPF 253
Query: 179 LELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGK 238
LELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGK
Sbjct: 254 LELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGK 313
Query: 239 HDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLD 298
HDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLD
Sbjct: 314 HDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLD 373
Query: 299 YIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRF 358
YIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRF
Sbjct: 374 YIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRF 433
Query: 359 SALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIIS 418
SALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIIS
Sbjct: 434 SALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIIS 493
Query: 419 KVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFT 478
KVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFT
Sbjct: 494 KVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFT 553
Query: 479 DMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHR 538
DMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHR
Sbjct: 554 DMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHR 613
Query: 539 GLPPRSLGVPAGEASPGCTP 558
GLPPRSLGVPAGEASPGCTP
Sbjct: 614 GLPPRSLGVPAGEASPGCTP 633
Score = 246 bits (628), Expect = 4e-65
Identities = 119/119 (100%), Positives = 119/119 (100%)
Query: 1 MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVG 60
MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVG
Sbjct: 1 MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVG 60
Query: 61 RTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ 119
RTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ
Sbjct: 61 RTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ 119
Score = 41.6 bits (96), Expect = 0.002
Identities = 41/132 (31%), Positives = 63/132 (47%), Gaps = 8/132 (6%)
Query: 24 VELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQ-VGRTEVVRSSLHPVFSKVFTVDY- 81
VEL R L D+D +KSDP + L + Q +Q V RTEVV+++L+PV+ + F V
Sbjct: 232 VELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVW-EAFKVSLS 290
Query: 82 ---YFEEVQRLRFEV--YDTHGPSGFSCQEDDFLGGMECTLGQIVAQKKVTRPLLLKFGR 136
EE + L+ V YD+ G F + M+ + AQ P + R
Sbjct: 291 SLCSCEETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRR 350
Query: 137 NAGKSTITVIAE 148
+ S + V+A+
Sbjct: 351 SYKNSGVVVLAD 362
Score = 39.7 bits (91), Expect = 0.007
Identities = 36/100 (36%), Positives = 52/100 (52%), Gaps = 15/100 (15%)
Query: 157 VELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVW-EAFKVSLS 215
VEL R L D+D +KSDP + L + Q +Q V RTEVV+++L+PV+ + F V
Sbjct: 24 VELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQ-VGRTEVVRSSLHPVFSKVFTVDY- 81
Query: 216 SLCSCEETRPLKCLVWDYDSRG-------KHDFIGEFSTT 248
EE + L+ V YD+ G + DF+G T
Sbjct: 82 ---YFEEVQRLRFEV--YDTHGPSGFSCQEDDFLGGMECT 116
>gi|18677733 copine IV [Homo sapiens]
Length = 557
Score = 783 bits (2022), Expect = 0.0
Identities = 377/535 (70%), Positives = 456/535 (85%), Gaps = 2/535 (0%)
Query: 9 AAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSS 68
AA T G +PC +KVELR++C+ + DRD L+K DP V L Q+ GQW +V RTEV+R+
Sbjct: 11 AANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFEVDRTEVIRTC 70
Query: 69 LHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQIVAQKKVTR 128
++PV+SK+FTVD+YFEEVQRLRFEV+D +E DFLGGMECTLGQIV+Q+K+++
Sbjct: 71 INPVYSKLFTVDFYFEEVQRLRFEVHDISSNHN-GLKEADFLGGMECTLGQIVSQRKLSK 129
Query: 129 PLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQ 188
LL K G AGKS+ITVIAE++SGN+ YVEL+F ARKLDDKD FSKSDPFLE++R+NDD
Sbjct: 130 SLL-KHGNTAGKSSITVIAEELSGNDDYVELAFNARKLDDKDFFSKSDPFLEIFRMNDDA 188
Query: 189 GLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGEFSTT 248
QLV+RTEVV NNL+P W++FKVS++SLCS + R LKC+VWD+DS GKHDFIGEF++T
Sbjct: 189 TQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNGKHDFIGEFTST 248
Query: 249 FEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDYIMGGCQIHF 308
F+EM+ A E Q QW+C+NPKYK K+++YKNSG V+L K H+++SFLDYIMGGCQI F
Sbjct: 249 FKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGTVILNLCKIHKMHSFLDYIMGGCQIQF 308
Query: 309 TVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFSALGFGARIP 368
TVAIDFTASNGDPRNSCSLHYI+PYQPNEYLKALV+VGEICQDYDSDK F A GFGARIP
Sbjct: 309 TVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIP 368
Query: 369 PKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKVARVAAAEE 428
P+Y VSHDFAINFN ++ EC GIQGVVEAYQ+CLP++QLYGPTN+APII KVA+ A+ E
Sbjct: 369 PEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEET 428
Query: 429 STGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTDMQVLDGDDG 488
+T +ASQY+ILLILTDGV+TDMADTREAIV AS LPMS+IIVGVGNADF+DMQ+LDGDDG
Sbjct: 429 NTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDG 488
Query: 489 VLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHRGLPPR 543
+LRSP+GEP LRDIVQFVPFR K+ASPAALAK VLAEVP QVV+YY+ +G+ P+
Sbjct: 489 ILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPK 543
>gi|5174421 copine 6 [Homo sapiens]
Length = 557
Score = 723 bits (1867), Expect = 0.0
Identities = 354/524 (67%), Positives = 433/524 (82%), Gaps = 3/524 (0%)
Query: 21 ASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVFSKVFTVD 80
AS+VELR+SC LLDRD LTK P V L + QWV+V RTEV+RS PVFS+V ++
Sbjct: 19 ASRVELRVSCHGLLDRDTLTKPHPCVLLKLYSDEQWVEVERTEVLRSCSSPVFSRVLALE 78
Query: 81 YYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQIVAQKKVTRPLLLKFGRNAGK 140
Y+FEE Q L+F V+D S + D FLG ECTLGQIV+Q KVT+PLLLK G+ AGK
Sbjct: 79 YFFEEKQPLQFHVFDAED-GATSPRNDTFLGSTECTLGQIVSQTKVTKPLLLKNGKTAGK 137
Query: 141 STITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVK 200
STIT++AE++SG N YV+L+FRA KLD+KDLFSKSDPF+E+Y+ N+DQ QLV+RTEVVK
Sbjct: 138 STITIVAEEVSGTNDYVQLTFRAYKLDNKDLFSKSDPFMEIYKTNEDQSDQLVWRTEVVK 197
Query: 201 NNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQK--AFEE 258
NNLNP WE F++SL SLCSC+ RPLK LV+DYDS GKHDFIGEF++TF+EMQ+ A
Sbjct: 198 NNLNPSWEPFRLSLHSLCSCDVHRPLKFLVYDYDSSGKHDFIGEFTSTFQEMQEGTANPG 257
Query: 259 GQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDYIMGGCQIHFTVAIDFTASN 318
+ QWDC+NPKY+ K+++YK+SG VVLA +V++FLDYIMGGCQI FTVAIDFTASN
Sbjct: 258 QEMQWDCINPKYRDKKKNYKSSGTVVLAQCTVEKVHTFLDYIMGGCQISFTVAIDFTASN 317
Query: 319 GDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFSALGFGARIPPKYEVSHDFA 378
GDPR+S SLH ++P QPN YL+AL +VG ICQDYDSDKRF A GFGARIPP +EVSHDFA
Sbjct: 318 GDPRSSQSLHCLSPRQPNHYLQALRAVGGICQDYDSDKRFPAFGFGARIPPNFEVSHDFA 377
Query: 379 INFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKVARVAAAEESTGKASQYYI 438
INF+PE+ ECE I GV+ +Y+ CLP++QLYGPTNVAPII++VA A E+STG+A++Y +
Sbjct: 378 INFDPENPECEEISGVIASYRRCLPQIQLYGPTNVAPIINRVAEPAQREQSTGQATKYSV 437
Query: 439 LLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTDMQVLDGDDGVLRSPRGEPA 498
LL+LTDGVV+DMA+TR AIVRASRLPMSIIIVGVGNADF+DM++LDGDDG LR PRG PA
Sbjct: 438 LLVLTDGVVSDMAETRTAIVRASRLPMSIIIVGVGNADFSDMRLLDGDDGPLRCPRGVPA 497
Query: 499 LRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHRGLPP 542
RDIVQFVPFR+ K+A+P+ALAKCVLAEVP+QVVEYY+ +G+ P
Sbjct: 498 ARDIVQFVPFRDFKDAAPSALAKCVLAEVPRQVVEYYASQGISP 541
>gi|4503015 copine III [Homo sapiens]
Length = 537
Score = 601 bits (1549), Expect = e-172
Identities = 298/531 (56%), Positives = 392/531 (73%), Gaps = 4/531 (0%)
Query: 16 LPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQ-WVQVGRTEVVRSSLHPVFS 74
+ A C +KV L +SC +LLD+D +KSDP L GQ W +V RTE +++ L+P FS
Sbjct: 1 MAAQCVTKVALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFS 60
Query: 75 KVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQIVAQKKVTRPLLLKF 134
K F +DYYFE VQ+L+F VYD + +DDFLG ECTLGQIV+ KK+TRPL++K
Sbjct: 61 KTFIIDYYFEVVQKLKFGVYDIDNKT-IELSDDDFLGECECTLGQIVSSKKLTRPLVMKT 119
Query: 135 GRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVY 194
GR AGK +IT+ AE+I N V ARKLD+KDLF KSDP+LE ++ D +V+
Sbjct: 120 GRPAGKGSITISAEEIKDNR-VVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVH 178
Query: 195 RTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQK 254
RTEVVKNNLNPVW FK+SL+SLC + + +K +DYD+ G HD IG F TT ++++
Sbjct: 179 RTEVVKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKE 238
Query: 255 AFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDYIMGGCQIHFTVAIDF 314
A +++C+N K +QK++SYKNSGV+ + + +FLDYIMGGCQ++FTV +DF
Sbjct: 239 ASRSSPVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLDYIMGGCQLNFTVGVDF 298
Query: 315 TASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFSALGFGARIPPKYEVS 374
T SNGDPR+ SLHYI+P NEYL AL SVG + QDYD+DK F A GFGA+IPP+++VS
Sbjct: 299 TGSNGDPRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVS 358
Query: 375 HDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKVARVAAAEESTGKAS 434
H+F +NFNP + C GIQG+VEAY++CLP+++LYGPTN +PII+ VAR AAA AS
Sbjct: 359 HEFPMNFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFSPIINHVARFAAAATQQQTAS 418
Query: 435 QYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTDMQVLDGDDGVLRSPR 494
QY++LLI+TDGV+TD+ +TR+AIV ASRLPMSIIIVGVG ADF+ M+ LDGD G LRSP
Sbjct: 419 QYFVLLIITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFSAMEFLDGDGGSLRSPL 478
Query: 495 GEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYY-SHRGLPPRS 544
GE A+RDIVQFVPFR+ +NA ALA+CVLAE+P+QVV Y+ +++ LPP++
Sbjct: 479 GEVAIRDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNTYKLLPPKN 529
>gi|30181236 copine II [Homo sapiens]
Length = 548
Score = 597 bits (1540), Expect = e-171
Identities = 292/540 (54%), Positives = 388/540 (71%), Gaps = 3/540 (0%)
Query: 3 AGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRT 62
+G A A P G P C KVEL +S ++LLDRD +KSDP L + G+W++ RT
Sbjct: 6 SGGAPAAGAAPMG-PQYCVCKVELSVSGQNLLDRDVTSKSDPFCVLFTENNGRWIEYDRT 64
Query: 63 EVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQIVA 122
E ++L+P FSK F +DY+FEEVQ+L+F ++D S E DFLG C+LG IV+
Sbjct: 65 ETAINNLNPAFSKKFVLDYHFEEVQKLKFALFD-QDKSSMRLDEHDFLGQFSCSLGTIVS 123
Query: 123 QKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELY 182
KK+TRPLLL + AGK IT+ A+++S N + LS R+LD KDLF KSDPFLE Y
Sbjct: 124 SKKITRPLLLLNDKPAGKGLITIAAQELSDNR-VITLSLAGRRLDKKDLFGKSDPFLEFY 182
Query: 183 RVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFI 242
+ DD LV+RTEV+K L+PVW+ F V L SLC + +P++ + +DYD+ G HDFI
Sbjct: 183 KPGDDGKWMLVHRTEVIKYTLDPVWKPFTVPLVSLCDGDMEKPIQVMCYDYDNDGGHDFI 242
Query: 243 GEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDYIMG 302
GEF T+ +M +A + +++C+NPK ++K+++YKNSG+++L K +R YSFLDYI+G
Sbjct: 243 GEFQTSVSQMCEARDSVPLEFECINPKKQRKKKNYKNSGIIILRSCKINRDYSFLDYILG 302
Query: 303 GCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFSALG 362
GCQ+ FTV IDFTASNG+P + SLHYINP NEYL A+ +VG+I QDYDSDK F ALG
Sbjct: 303 GCQLMFTVGIDFTASNGNPLDPSSLHYINPMGTNEYLSAIWAVGQIIQDYDSDKMFPALG 362
Query: 363 FGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKVAR 422
FGA++PP ++VSH+FAINFNP + C G+ G+ +AY CLP ++ YGPTN +PI++ VAR
Sbjct: 363 FGAQLPPDWKVSHEFAINFNPTNPFCSGVDGIAQAYSACLPHIRFYGPTNFSPIVNHVAR 422
Query: 423 VAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTDMQV 482
AA A+QY+ILLI+TDGV++DM +TR A+V+AS+LPMSIIIVGVGNADF M+
Sbjct: 423 FAAQATQQRTATQYFILLIITDGVISDMEETRHAVVQASKLPMSIIIVGVGNADFAAMEF 482
Query: 483 LDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHRGLPP 542
LDGD +LRS GE A RDIVQFVPFRE +NA+ LAK VLAE+P+QVV+Y+ H+ LPP
Sbjct: 483 LDGDSRMLRSHTGEEAARDIVQFVPFREFRNAAKETLAKAVLAELPQQVVQYFKHKNLPP 542
>gi|23397708 copine I isoform a [Homo sapiens]
Length = 537
Score = 546 bits (1406), Expect = e-155
Identities = 277/526 (52%), Positives = 363/526 (69%), Gaps = 8/526 (1%)
Query: 18 APCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQG-QWVQVGRTEVVRSSLHPVFSKV 76
A C + V+L +SC HL+D+D +KSDP LLQ G W ++GRTE VR+ P FSK
Sbjct: 2 AHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSPEFSKT 61
Query: 77 FTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQIVAQKKVTRPLLLKFGR 136
++Y FE VQ+LRF +YD + ++DDFLGG EC+LGQIV+ + +T PL+LK G+
Sbjct: 62 LQLEYRFETVQKLRFGIYDIDNKTP-ELRDDDFLGGAECSLGQIVSSQVLTLPLMLKPGK 120
Query: 137 NAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRT 196
AG+ TITV A+++ N V + AR LD KD KSDPFLE +R D + LVYR+
Sbjct: 121 PAGRGTITVSAQELKDNR-VVTMEVEARNLDKKDFLGKSDPFLEFFRQGDGKW-HLVYRS 178
Query: 197 EVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQKAF 256
EV+KNNLNP W+ F V + C + P++ DYDS G HD IG F T+ ++Q
Sbjct: 179 EVIKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGSHDLIGTFHTSLAQLQAV- 237
Query: 257 EEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDYIMGGCQIHFTVAIDFTA 316
A+++C++P+ +QK++SYKNSG + + + YSFLDY+MGGCQI+FTV +DFT
Sbjct: 238 ---PAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLDYVMGGCQINFTVGVDFTG 294
Query: 317 SNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFSALGFGARIPPKYEVSHD 376
SNGDP + SLHY++P NEYL AL SVG + QDYDSDK F A GFGA++PP ++VSH+
Sbjct: 295 SNGDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHE 354
Query: 377 FAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKVARVAAAEESTGKASQY 436
FA+NFNP + C GIQG+V+AY+ LP+V+LYGPTN APII+ VAR AA G ASQY
Sbjct: 355 FALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVARFAAQAAHQGTASQY 414
Query: 437 YILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTDMQVLDGDDGVLRSPRGE 496
++LL+LTDG VTD+ TREA+VRAS LPMS+IIVGVG ADF M+ LD D G L + G+
Sbjct: 415 FMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFEAMEQLDADGGPLHTRSGQ 474
Query: 497 PALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHRGLPP 542
A RDIVQFVP+R +NA ALA+ VLAEVP Q+V Y+ +G P
Sbjct: 475 AAARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQGWAP 520
>gi|23397706 copine I isoform a [Homo sapiens]
Length = 537
Score = 546 bits (1406), Expect = e-155
Identities = 277/526 (52%), Positives = 363/526 (69%), Gaps = 8/526 (1%)
Query: 18 APCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQG-QWVQVGRTEVVRSSLHPVFSKV 76
A C + V+L +SC HL+D+D +KSDP LLQ G W ++GRTE VR+ P FSK
Sbjct: 2 AHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSPEFSKT 61
Query: 77 FTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQIVAQKKVTRPLLLKFGR 136
++Y FE VQ+LRF +YD + ++DDFLGG EC+LGQIV+ + +T PL+LK G+
Sbjct: 62 LQLEYRFETVQKLRFGIYDIDNKTP-ELRDDDFLGGAECSLGQIVSSQVLTLPLMLKPGK 120
Query: 137 NAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRT 196
AG+ TITV A+++ N V + AR LD KD KSDPFLE +R D + LVYR+
Sbjct: 121 PAGRGTITVSAQELKDNR-VVTMEVEARNLDKKDFLGKSDPFLEFFRQGDGKW-HLVYRS 178
Query: 197 EVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQKAF 256
EV+KNNLNP W+ F V + C + P++ DYDS G HD IG F T+ ++Q
Sbjct: 179 EVIKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGSHDLIGTFHTSLAQLQAV- 237
Query: 257 EEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDYIMGGCQIHFTVAIDFTA 316
A+++C++P+ +QK++SYKNSG + + + YSFLDY+MGGCQI+FTV +DFT
Sbjct: 238 ---PAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLDYVMGGCQINFTVGVDFTG 294
Query: 317 SNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFSALGFGARIPPKYEVSHD 376
SNGDP + SLHY++P NEYL AL SVG + QDYDSDK F A GFGA++PP ++VSH+
Sbjct: 295 SNGDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHE 354
Query: 377 FAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKVARVAAAEESTGKASQY 436
FA+NFNP + C GIQG+V+AY+ LP+V+LYGPTN APII+ VAR AA G ASQY
Sbjct: 355 FALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVARFAAQAAHQGTASQY 414
Query: 437 YILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTDMQVLDGDDGVLRSPRGE 496
++LL+LTDG VTD+ TREA+VRAS LPMS+IIVGVG ADF M+ LD D G L + G+
Sbjct: 415 FMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFEAMEQLDADGGPLHTRSGQ 474
Query: 497 PALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHRGLPP 542
A RDIVQFVP+R +NA ALA+ VLAEVP Q+V Y+ +G P
Sbjct: 475 AAARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQGWAP 520
>gi|23397704 copine I isoform a [Homo sapiens]
Length = 537
Score = 546 bits (1406), Expect = e-155
Identities = 277/526 (52%), Positives = 363/526 (69%), Gaps = 8/526 (1%)
Query: 18 APCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQG-QWVQVGRTEVVRSSLHPVFSKV 76
A C + V+L +SC HL+D+D +KSDP LLQ G W ++GRTE VR+ P FSK
Sbjct: 2 AHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSPEFSKT 61
Query: 77 FTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQIVAQKKVTRPLLLKFGR 136
++Y FE VQ+LRF +YD + ++DDFLGG EC+LGQIV+ + +T PL+LK G+
Sbjct: 62 LQLEYRFETVQKLRFGIYDIDNKTP-ELRDDDFLGGAECSLGQIVSSQVLTLPLMLKPGK 120
Query: 137 NAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRT 196
AG+ TITV A+++ N V + AR LD KD KSDPFLE +R D + LVYR+
Sbjct: 121 PAGRGTITVSAQELKDNR-VVTMEVEARNLDKKDFLGKSDPFLEFFRQGDGKW-HLVYRS 178
Query: 197 EVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQKAF 256
EV+KNNLNP W+ F V + C + P++ DYDS G HD IG F T+ ++Q
Sbjct: 179 EVIKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGSHDLIGTFHTSLAQLQAV- 237
Query: 257 EEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDYIMGGCQIHFTVAIDFTA 316
A+++C++P+ +QK++SYKNSG + + + YSFLDY+MGGCQI+FTV +DFT
Sbjct: 238 ---PAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLDYVMGGCQINFTVGVDFTG 294
Query: 317 SNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFSALGFGARIPPKYEVSHD 376
SNGDP + SLHY++P NEYL AL SVG + QDYDSDK F A GFGA++PP ++VSH+
Sbjct: 295 SNGDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHE 354
Query: 377 FAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKVARVAAAEESTGKASQY 436
FA+NFNP + C GIQG+V+AY+ LP+V+LYGPTN APII+ VAR AA G ASQY
Sbjct: 355 FALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVARFAAQAAHQGTASQY 414
Query: 437 YILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTDMQVLDGDDGVLRSPRGE 496
++LL+LTDG VTD+ TREA+VRAS LPMS+IIVGVG ADF M+ LD D G L + G+
Sbjct: 415 FMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFEAMEQLDADGGPLHTRSGQ 474
Query: 497 PALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHRGLPP 542
A RDIVQFVP+R +NA ALA+ VLAEVP Q+V Y+ +G P
Sbjct: 475 AAARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQGWAP 520
>gi|23397702 copine I isoform a [Homo sapiens]
Length = 537
Score = 546 bits (1406), Expect = e-155
Identities = 277/526 (52%), Positives = 363/526 (69%), Gaps = 8/526 (1%)
Query: 18 APCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQG-QWVQVGRTEVVRSSLHPVFSKV 76
A C + V+L +SC HL+D+D +KSDP LLQ G W ++GRTE VR+ P FSK
Sbjct: 2 AHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSPEFSKT 61
Query: 77 FTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQIVAQKKVTRPLLLKFGR 136
++Y FE VQ+LRF +YD + ++DDFLGG EC+LGQIV+ + +T PL+LK G+
Sbjct: 62 LQLEYRFETVQKLRFGIYDIDNKTP-ELRDDDFLGGAECSLGQIVSSQVLTLPLMLKPGK 120
Query: 137 NAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRT 196
AG+ TITV A+++ N V + AR LD KD KSDPFLE +R D + LVYR+
Sbjct: 121 PAGRGTITVSAQELKDNR-VVTMEVEARNLDKKDFLGKSDPFLEFFRQGDGKW-HLVYRS 178
Query: 197 EVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQKAF 256
EV+KNNLNP W+ F V + C + P++ DYDS G HD IG F T+ ++Q
Sbjct: 179 EVIKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGSHDLIGTFHTSLAQLQAV- 237
Query: 257 EEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDYIMGGCQIHFTVAIDFTA 316
A+++C++P+ +QK++SYKNSG + + + YSFLDY+MGGCQI+FTV +DFT
Sbjct: 238 ---PAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLDYVMGGCQINFTVGVDFTG 294
Query: 317 SNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFSALGFGARIPPKYEVSHD 376
SNGDP + SLHY++P NEYL AL SVG + QDYDSDK F A GFGA++PP ++VSH+
Sbjct: 295 SNGDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHE 354
Query: 377 FAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKVARVAAAEESTGKASQY 436
FA+NFNP + C GIQG+V+AY+ LP+V+LYGPTN APII+ VAR AA G ASQY
Sbjct: 355 FALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVARFAAQAAHQGTASQY 414
Query: 437 YILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTDMQVLDGDDGVLRSPRGE 496
++LL+LTDG VTD+ TREA+VRAS LPMS+IIVGVG ADF M+ LD D G L + G+
Sbjct: 415 FMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFEAMEQLDADGGPLHTRSGQ 474
Query: 497 PALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHRGLPP 542
A RDIVQFVP+R +NA ALA+ VLAEVP Q+V Y+ +G P
Sbjct: 475 AAARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQGWAP 520
>gi|23397700 copine I isoform a [Homo sapiens]
Length = 537
Score = 546 bits (1406), Expect = e-155
Identities = 277/526 (52%), Positives = 363/526 (69%), Gaps = 8/526 (1%)
Query: 18 APCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQG-QWVQVGRTEVVRSSLHPVFSKV 76
A C + V+L +SC HL+D+D +KSDP LLQ G W ++GRTE VR+ P FSK
Sbjct: 2 AHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSPEFSKT 61
Query: 77 FTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQIVAQKKVTRPLLLKFGR 136
++Y FE VQ+LRF +YD + ++DDFLGG EC+LGQIV+ + +T PL+LK G+
Sbjct: 62 LQLEYRFETVQKLRFGIYDIDNKTP-ELRDDDFLGGAECSLGQIVSSQVLTLPLMLKPGK 120
Query: 137 NAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRT 196
AG+ TITV A+++ N V + AR LD KD KSDPFLE +R D + LVYR+
Sbjct: 121 PAGRGTITVSAQELKDNR-VVTMEVEARNLDKKDFLGKSDPFLEFFRQGDGKW-HLVYRS 178
Query: 197 EVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQKAF 256
EV+KNNLNP W+ F V + C + P++ DYDS G HD IG F T+ ++Q
Sbjct: 179 EVIKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGSHDLIGTFHTSLAQLQAV- 237
Query: 257 EEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDYIMGGCQIHFTVAIDFTA 316
A+++C++P+ +QK++SYKNSG + + + YSFLDY+MGGCQI+FTV +DFT
Sbjct: 238 ---PAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLDYVMGGCQINFTVGVDFTG 294
Query: 317 SNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFSALGFGARIPPKYEVSHD 376
SNGDP + SLHY++P NEYL AL SVG + QDYDSDK F A GFGA++PP ++VSH+
Sbjct: 295 SNGDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHE 354
Query: 377 FAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKVARVAAAEESTGKASQY 436
FA+NFNP + C GIQG+V+AY+ LP+V+LYGPTN APII+ VAR AA G ASQY
Sbjct: 355 FALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVARFAAQAAHQGTASQY 414
Query: 437 YILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTDMQVLDGDDGVLRSPRGE 496
++LL+LTDG VTD+ TREA+VRAS LPMS+IIVGVG ADF M+ LD D G L + G+
Sbjct: 415 FMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFEAMEQLDADGGPLHTRSGQ 474
Query: 497 PALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHRGLPP 542
A RDIVQFVP+R +NA ALA+ VLAEVP Q+V Y+ +G P
Sbjct: 475 AAARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQGWAP 520
>gi|23397698 copine I isoform a [Homo sapiens]
Length = 537
Score = 546 bits (1406), Expect = e-155
Identities = 277/526 (52%), Positives = 363/526 (69%), Gaps = 8/526 (1%)
Query: 18 APCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQG-QWVQVGRTEVVRSSLHPVFSKV 76
A C + V+L +SC HL+D+D +KSDP LLQ G W ++GRTE VR+ P FSK
Sbjct: 2 AHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSPEFSKT 61
Query: 77 FTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQIVAQKKVTRPLLLKFGR 136
++Y FE VQ+LRF +YD + ++DDFLGG EC+LGQIV+ + +T PL+LK G+
Sbjct: 62 LQLEYRFETVQKLRFGIYDIDNKTP-ELRDDDFLGGAECSLGQIVSSQVLTLPLMLKPGK 120
Query: 137 NAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRT 196
AG+ TITV A+++ N V + AR LD KD KSDPFLE +R D + LVYR+
Sbjct: 121 PAGRGTITVSAQELKDNR-VVTMEVEARNLDKKDFLGKSDPFLEFFRQGDGKW-HLVYRS 178
Query: 197 EVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQKAF 256
EV+KNNLNP W+ F V + C + P++ DYDS G HD IG F T+ ++Q
Sbjct: 179 EVIKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGSHDLIGTFHTSLAQLQAV- 237
Query: 257 EEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDYIMGGCQIHFTVAIDFTA 316
A+++C++P+ +QK++SYKNSG + + + YSFLDY+MGGCQI+FTV +DFT
Sbjct: 238 ---PAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLDYVMGGCQINFTVGVDFTG 294
Query: 317 SNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFSALGFGARIPPKYEVSHD 376
SNGDP + SLHY++P NEYL AL SVG + QDYDSDK F A GFGA++PP ++VSH+
Sbjct: 295 SNGDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHE 354
Query: 377 FAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKVARVAAAEESTGKASQY 436
FA+NFNP + C GIQG+V+AY+ LP+V+LYGPTN APII+ VAR AA G ASQY
Sbjct: 355 FALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVARFAAQAAHQGTASQY 414
Query: 437 YILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTDMQVLDGDDGVLRSPRGE 496
++LL+LTDG VTD+ TREA+VRAS LPMS+IIVGVG ADF M+ LD D G L + G+
Sbjct: 415 FMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFEAMEQLDADGGPLHTRSGQ 474
Query: 497 PALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHRGLPP 542
A RDIVQFVP+R +NA ALA+ VLAEVP Q+V Y+ +G P
Sbjct: 475 AAARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQGWAP 520
>gi|23397696 copine I isoform a [Homo sapiens]
Length = 537
Score = 546 bits (1406), Expect = e-155
Identities = 277/526 (52%), Positives = 363/526 (69%), Gaps = 8/526 (1%)
Query: 18 APCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQG-QWVQVGRTEVVRSSLHPVFSKV 76
A C + V+L +SC HL+D+D +KSDP LLQ G W ++GRTE VR+ P FSK
Sbjct: 2 AHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSPEFSKT 61
Query: 77 FTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQIVAQKKVTRPLLLKFGR 136
++Y FE VQ+LRF +YD + ++DDFLGG EC+LGQIV+ + +T PL+LK G+
Sbjct: 62 LQLEYRFETVQKLRFGIYDIDNKTP-ELRDDDFLGGAECSLGQIVSSQVLTLPLMLKPGK 120
Query: 137 NAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRT 196
AG+ TITV A+++ N V + AR LD KD KSDPFLE +R D + LVYR+
Sbjct: 121 PAGRGTITVSAQELKDNR-VVTMEVEARNLDKKDFLGKSDPFLEFFRQGDGKW-HLVYRS 178
Query: 197 EVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQKAF 256
EV+KNNLNP W+ F V + C + P++ DYDS G HD IG F T+ ++Q
Sbjct: 179 EVIKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGSHDLIGTFHTSLAQLQAV- 237
Query: 257 EEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDYIMGGCQIHFTVAIDFTA 316
A+++C++P+ +QK++SYKNSG + + + YSFLDY+MGGCQI+FTV +DFT
Sbjct: 238 ---PAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLDYVMGGCQINFTVGVDFTG 294
Query: 317 SNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFSALGFGARIPPKYEVSHD 376
SNGDP + SLHY++P NEYL AL SVG + QDYDSDK F A GFGA++PP ++VSH+
Sbjct: 295 SNGDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHE 354
Query: 377 FAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKVARVAAAEESTGKASQY 436
FA+NFNP + C GIQG+V+AY+ LP+V+LYGPTN APII+ VAR AA G ASQY
Sbjct: 355 FALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVARFAAQAAHQGTASQY 414
Query: 437 YILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTDMQVLDGDDGVLRSPRGE 496
++LL+LTDG VTD+ TREA+VRAS LPMS+IIVGVG ADF M+ LD D G L + G+
Sbjct: 415 FMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFEAMEQLDADGGPLHTRSGQ 474
Query: 497 PALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHRGLPP 542
A RDIVQFVP+R +NA ALA+ VLAEVP Q+V Y+ +G P
Sbjct: 475 AAARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQGWAP 520
>gi|197333761 copine I isoform b [Homo sapiens]
Length = 542
Score = 546 bits (1406), Expect = e-155
Identities = 277/526 (52%), Positives = 363/526 (69%), Gaps = 8/526 (1%)
Query: 18 APCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQG-QWVQVGRTEVVRSSLHPVFSKV 76
A C + V+L +SC HL+D+D +KSDP LLQ G W ++GRTE VR+ P FSK
Sbjct: 7 AHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSPEFSKT 66
Query: 77 FTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQIVAQKKVTRPLLLKFGR 136
++Y FE VQ+LRF +YD + ++DDFLGG EC+LGQIV+ + +T PL+LK G+
Sbjct: 67 LQLEYRFETVQKLRFGIYDIDNKTP-ELRDDDFLGGAECSLGQIVSSQVLTLPLMLKPGK 125
Query: 137 NAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRT 196
AG+ TITV A+++ N V + AR LD KD KSDPFLE +R D + LVYR+
Sbjct: 126 PAGRGTITVSAQELKDNR-VVTMEVEARNLDKKDFLGKSDPFLEFFRQGDGKW-HLVYRS 183
Query: 197 EVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQKAF 256
EV+KNNLNP W+ F V + C + P++ DYDS G HD IG F T+ ++Q
Sbjct: 184 EVIKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGSHDLIGTFHTSLAQLQAV- 242
Query: 257 EEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDYIMGGCQIHFTVAIDFTA 316
A+++C++P+ +QK++SYKNSG + + + YSFLDY+MGGCQI+FTV +DFT
Sbjct: 243 ---PAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLDYVMGGCQINFTVGVDFTG 299
Query: 317 SNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFSALGFGARIPPKYEVSHD 376
SNGDP + SLHY++P NEYL AL SVG + QDYDSDK F A GFGA++PP ++VSH+
Sbjct: 300 SNGDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHE 359
Query: 377 FAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKVARVAAAEESTGKASQY 436
FA+NFNP + C GIQG+V+AY+ LP+V+LYGPTN APII+ VAR AA G ASQY
Sbjct: 360 FALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVARFAAQAAHQGTASQY 419
Query: 437 YILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTDMQVLDGDDGVLRSPRGE 496
++LL+LTDG VTD+ TREA+VRAS LPMS+IIVGVG ADF M+ LD D G L + G+
Sbjct: 420 FMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFEAMEQLDADGGPLHTRSGQ 479
Query: 497 PALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHRGLPP 542
A RDIVQFVP+R +NA ALA+ VLAEVP Q+V Y+ +G P
Sbjct: 480 AAARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQGWAP 525
>gi|25121972 copine VIII [Homo sapiens]
Length = 564
Score = 508 bits (1308), Expect = e-144
Identities = 277/535 (51%), Positives = 367/535 (68%), Gaps = 24/535 (4%)
Query: 21 ASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQG--QWVQVGRTEVVRSSLHPVFSKVFT 78
A++VE+ +SCR+LLDRD +KSDP L Q G +W + GRTEV+ ++L+P F + F
Sbjct: 23 ATRVEVSVSCRNLLDRDTFSKSDPICVLYVQGVGNKEWREFGRTEVIDNTLNPDFVRKFI 82
Query: 79 VDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQIVAQK--KVTRPLLLKFGR 136
+DY+FEE + LRF++YD S + + DFLG + CTLG+IV + ++ +P++ G+
Sbjct: 83 LDYFFEERENLRFDLYDVDSKSP-NLSKHDFLGQVFCTLGEIVGSQGSRLEKPIVGIPGK 141
Query: 137 NAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRT 196
G TI + AE+++ V + F A KLD KD F KSDPFL YR N+D + ++T
Sbjct: 142 KCG--TIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKT 199
Query: 197 EVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQKAF 256
EVVKN LNPVW+AFK+S+ +LC+ + R +K V+D+D G HDFIGEF+T++ E+ +
Sbjct: 200 EVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELSR-- 257
Query: 257 EEGQAQ---WDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDYIMGGCQIHFTVAID 313
GQ+Q ++ VNPK K K++ Y NSG V L SFLDYI GG QI+FTVAID
Sbjct: 258 --GQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAID 315
Query: 314 FTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFSALGFGARIPPKYEV 373
FTASNG+P SLHY+NPYQ N Y AL +VGEI QDYDSDK F ALGFGA++PP +
Sbjct: 316 FTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRI 375
Query: 374 SHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKVARVAAAEESTGKA 433
SH+FA+N NP++ C+GI+GV+EAY L VQLYGPTN AP+I+ VAR A+ S
Sbjct: 376 SHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYAS---SVKDG 432
Query: 434 SQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTDMQVLDGDDGVLRSP 493
SQY++LLI+TDGV++DMA T+E+IV AS+LPMSIIIVGVG A+F M LDGDD V S
Sbjct: 433 SQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDD-VRVSS 491
Query: 494 RGEPALRDIVQFVPFRELKN------ASPAALAKCVLAEVPKQVVEYYSHRGLPP 542
RG+ A RDIVQFVPFR+ + S A LAK VLAE+P+Q + Y RG+ P
Sbjct: 492 RGKYAERDIVQFVPFRDYIDRSGNHILSMARLAKDVLAEIPEQFLSYMRARGIKP 546
>gi|25141323 copine V [Homo sapiens]
Length = 593
Score = 489 bits (1258), Expect = e-138
Identities = 278/579 (48%), Positives = 364/579 (62%), Gaps = 46/579 (7%)
Query: 14 GGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQG--QWVQVGRTEVVRSSLHP 71
G +PA +KVE+ +SCR+LLD+D +KSDP + Q QW + GRTEV+ ++L+P
Sbjct: 18 GSIPA---TKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNP 74
Query: 72 VFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQIVAQ--KKVTRP 129
F + F VDY+FEE Q LRF++YD S + DFLG CTLG+IV ++ +P
Sbjct: 75 DFVRKFIVDYFFEEKQNLRFDLYDVDSKSP-DLSKHDFLGQAFCTLGEIVGSPGSRLEKP 133
Query: 130 LLL---KFGRNAGK---------------STITVIAEDISGNNGYVELSFRARKLDDKDL 171
L + GK TI + AE++S + F A KLD KD
Sbjct: 134 LTIGAFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDF 193
Query: 172 FSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVW 231
F KSDPFL YR N+D + ++TEV+KN LNPVW+ F + + +LC+ + R +K V+
Sbjct: 194 FGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVY 253
Query: 232 DYDSRGKHDFIGEFSTTFEEMQKAFEEGQAQ---WDCVNPKYKQKRRSYKNSGVVVLADL 288
D+D G HDFIGEF+T++ E+ + GQ+Q ++ VNPK K K++ Y NSG V L
Sbjct: 254 DWDRDGSHDFIGEFTTSYRELAR----GQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSF 309
Query: 289 KFHRVYSFLDYIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEI 348
+FLDYI GG QI+FTVAIDFTASNG+P S SLHY++PYQ N Y AL +VGEI
Sbjct: 310 AVESECTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEI 369
Query: 349 CQDYDSDKRFSALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLY 408
Q YDSDK F ALGFGA++PP VSH+F +N N E+ C GI G++EAY L VQLY
Sbjct: 370 IQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLY 429
Query: 409 GPTNVAPIISKVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSII 468
GPTN AP+++ VAR AAA + SQY +LLI+TDGV++DMA T+EAIV A++LPMSII
Sbjct: 430 GPTNFAPVVTHVARNAAAVQD---GSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSII 486
Query: 469 IVGVGNADFTDMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKN------ASPAALAKC 522
IVGVG A+F M LDGDD V S RG+ A RDIVQFVPFR+ + S A LA+
Sbjct: 487 IVGVGQAEFDAMVELDGDD-VRISSRGKLAERDIVQFVPFRDYVDRTGNHVLSMARLARD 545
Query: 523 VLAEVPKQVVEYYSHRGL---PPRSLGVPAGEASPGCTP 558
VLAE+P Q+V Y +G+ PP + + SP TP
Sbjct: 546 VLAEIPDQLVSYMKAQGIRPRPPPAAPTHSPSQSPARTP 584
>gi|88703066 copine-like protein [Homo sapiens]
Length = 553
Score = 480 bits (1236), Expect = e-135
Identities = 268/548 (48%), Positives = 359/548 (65%), Gaps = 22/548 (4%)
Query: 21 ASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQG--QWVQVGRTEVVRSSLHPVFSKVFT 78
A+K+E+ +SCR+LLD D +KSDP V L Q++ +W + GRTEV+ ++L+P F + F
Sbjct: 13 ATKIEITVSCRNLLDLDTFSKSDPMVVLYTQSRASQEWREFGRTEVIDNTLNPDFVRKFV 72
Query: 79 VDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQIVAQK--KVTRPLLLKFGR 136
+DY+FEE Q LRF+VY+ + S + DFLG LG+++ + +V R L G+
Sbjct: 73 LDYFFEEKQNLRFDVYNVDSKTNIS-KPKDFLGQAFLALGEVIGGQGSRVERTLTGVPGK 131
Query: 137 NAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRT 196
G TI + AE++S + A KLD KD F KSDPFL YR N+D + ++T
Sbjct: 132 KCG--TILLTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKT 189
Query: 197 EVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQKAF 256
EVVKN LNPVW+ F + + +LC+ + R +K V+D+D G HDFIGEF+T++ E+ KA
Sbjct: 190 EVVKNTLNPVWQPFSIPVRALCNGDYDRTVKIDVYDWDRDGSHDFIGEFTTSYRELSKAQ 249
Query: 257 EEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDYIMGGCQIHFTVAIDFTA 316
+ ++ +NP+ K K++ Y NSG V L ++F+DYI GG Q++FTVAIDFTA
Sbjct: 250 NQFTV-YEVLNPRKKCKKKKYVNSGTVTLLSFSVDSEFTFVDYIKGGTQLNFTVAIDFTA 308
Query: 317 SNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFSALGFGARIPPKYEVSHD 376
SNG+P SLHY++PYQ + Y AL +VGEI QDYDSDK F A GFGA++PP+ +SH
Sbjct: 309 SNGNPLQPTSLHYMSPYQLSAYAMALKAVGEIIQDYDSDKLFPAYGFGAKLPPEGRISHQ 368
Query: 377 FAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKVARVAAAEESTGKASQY 436
F +N N ED C GI+GV+E+Y L VQLYGPT AP+I++VAR AAA+ S G SQY
Sbjct: 369 FPLNNNDEDPNCAGIEGVLESYFQSLRTVQLYGPTYFAPVINQVAR-AAAKISDG--SQY 425
Query: 437 YILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTDMQVLDGDDGVLRSPRGE 496
Y+LLI+TDGV++DM T+EAIV AS LPMSIIIVGVG A F M+ LDGDD V S RG
Sbjct: 426 YVLLIITDGVISDMTQTKEAIVSASSLPMSIIIVGVGPAMFEAMEELDGDD-VRVSSRGR 484
Query: 497 PALRDIVQFVPFRELKN------ASPAALAKCVLAEVPKQVVEYYSHRGLPPRSLGVPAG 550
A RDIVQFVPFR+ + S A LAK VLAE+P+Q++ Y R + PR P
Sbjct: 485 YAERDIVQFVPFRDYVDRSGNQVLSMARLAKDVLAEIPEQLLSYMRTRDIQPR----PPP 540
Query: 551 EASPGCTP 558
A+P P
Sbjct: 541 PANPSPIP 548
>gi|47157322 protein kinase C, beta isoform 1 [Homo sapiens]
Length = 671
Score = 52.0 bits (123), Expect = 1e-06
Identities = 31/98 (31%), Positives = 52/98 (53%), Gaps = 5/98 (5%)
Query: 163 ARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVW-EAFKVSLSSLCSCE 221
A+ L D SDP+++L + D + + +T+ +K +LNP W E F+ L +
Sbjct: 180 AKNLVPMDPNGLSDPYVKLKLIPDPKS-ESKQKTKTIKCSLNPEWNETFRFQLKE---SD 235
Query: 222 ETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQKAFEEG 259
+ R L +WD+D ++DF+G S E+QKA +G
Sbjct: 236 KDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKASVDG 273
>gi|20127450 protein kinase C, beta isoform 2 [Homo sapiens]
Length = 673
Score = 52.0 bits (123), Expect = 1e-06
Identities = 31/98 (31%), Positives = 52/98 (53%), Gaps = 5/98 (5%)
Query: 163 ARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVW-EAFKVSLSSLCSCE 221
A+ L D SDP+++L + D + + +T+ +K +LNP W E F+ L +
Sbjct: 180 AKNLVPMDPNGLSDPYVKLKLIPDPKS-ESKQKTKTIKCSLNPEWNETFRFQLKE---SD 235
Query: 222 ETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQKAFEEG 259
+ R L +WD+D ++DF+G S E+QKA +G
Sbjct: 236 KDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKASVDG 273
>gi|13384594 protein kinase C, gamma [Homo sapiens]
Length = 697
Score = 49.7 bits (117), Expect = 7e-06
Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 3/97 (3%)
Query: 163 ARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEE 222
AR L D SDP+++L + D + L +T VK LNPVW + + +L +
Sbjct: 180 ARNLIPMDPNGLSDPYVKLKLIPDPRNLTK-QKTRTVKATLNPVWN--ETFVFNLKPGDV 236
Query: 223 TRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQKAFEEG 259
R L VWD+D ++DF+G S E+ KA +G
Sbjct: 237 ERRLSVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDG 273
Score = 38.9 bits (89), Expect = 0.013
Identities = 29/106 (27%), Positives = 55/106 (51%), Gaps = 7/106 (6%)
Query: 18 APCASKVELRLS-CRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVFSKV 76
AP A ++ + + R+L+ DP SDP V L + + +T V+++L+PV+++
Sbjct: 167 APTADEIHVTVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNET 226
Query: 77 FTVDYYFEEVQ-RLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQIV 121
F + +V+ RL EV+D S +DF+G M + +++
Sbjct: 227 FVFNLKPGDVERRLSVEVWDWDRTS-----RNDFMGAMSFGVSELL 267
>gi|28376627 synaptotagmin IX [Homo sapiens]
Length = 491
Score = 46.6 bits (109), Expect = 6e-05
Identities = 60/203 (29%), Positives = 88/203 (43%), Gaps = 41/203 (20%)
Query: 61 RTEVVRSSLHPVFSKVFT--VDYYFEEVQRLRFEVYD-----THGPSGFSCQEDDFLG-- 111
+T+V R +L+PVF +VF V Y E ++L F VYD H G D FL
Sbjct: 273 QTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIG-QVVVDHFLDLA 331
Query: 112 --GMECTLG---QIVAQKKVTRPLL---LKFGRNAGKSTITVIAEDISGNNGYVELSFRA 163
EC L + V V L L + AG+ TIT+I +A
Sbjct: 332 DFPRECILWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITII---------------KA 376
Query: 164 RKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWE---AFKVSLSSLCSC 220
R L D+ SDP++++ + D + L+ +T +N LNPV+ F V ++
Sbjct: 377 RNLKAMDITGASDPYVKVSLMCDGRRLK-KRKTSTKRNTLNPVYNEAIVFDVPPENI--- 432
Query: 221 EETRPLKCLVWDYDSRGKHDFIG 243
+ L V DYD G ++ IG
Sbjct: 433 -DQIHLSIAVMDYDRVGHNEIIG 454
Score = 42.7 bits (99), Expect = 9e-04
Identities = 28/86 (32%), Positives = 46/86 (53%), Gaps = 10/86 (11%)
Query: 162 RARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEA---FKVSLSSLC 218
+A L KD SDP++++Y + D + ++T+V + LNPV++ F V + L
Sbjct: 243 KAVNLPAKDFSGTSDPYVKIYLLPDRK---TKHQTKVHRKTLNPVFDEVFLFPVPYNDL- 298
Query: 219 SCEETRPLKCLVWDYDSRGKHDFIGE 244
E R L V+D+D +HD IG+
Sbjct: 299 ---EARKLHFSVYDFDRFSRHDLIGQ 321
Score = 30.8 bits (68), Expect = 3.4
Identities = 17/76 (22%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Query: 19 PCASKVELRL-SCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVFSKVF 77
P A ++ + + R+L D SDP V + G+ ++ +T R++L+PV+++
Sbjct: 364 PTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAI 423
Query: 78 TVDYYFEEVQRLRFEV 93
D E + ++ +
Sbjct: 424 VFDVPPENIDQIHLSI 439
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 45.8 bits (107), Expect = 1e-04
Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 8/91 (8%)
Query: 162 RARKLDDKDLFSKSDPFLELY--------RVNDDQGLQLVYRTEVVKNNLNPVWEAFKVS 213
+AR L +D SDPF+++Y V + + RT+ V+ +LNP W +
Sbjct: 4715 QARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIY 4774
Query: 214 LSSLCSCEETRPLKCLVWDYDSRGKHDFIGE 244
S + + L+ VWDYD +DF+GE
Sbjct: 4775 KSISMEQLKKKTLEVTVWDYDRFSSNDFLGE 4805
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 45.8 bits (107), Expect = 1e-04
Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 8/91 (8%)
Query: 162 RARKLDDKDLFSKSDPFLELY--------RVNDDQGLQLVYRTEVVKNNLNPVWEAFKVS 213
+AR L +D SDPF+++Y V + + RT+ V+ +LNP W +
Sbjct: 4715 QARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIY 4774
Query: 214 LSSLCSCEETRPLKCLVWDYDSRGKHDFIGE 244
S + + L+ VWDYD +DF+GE
Sbjct: 4775 KSISMEQLKKKTLEVTVWDYDRFSSNDFLGE 4805
>gi|4506067 protein kinase C, alpha [Homo sapiens]
Length = 672
Score = 45.1 bits (105), Expect = 2e-04
Identities = 27/93 (29%), Positives = 48/93 (51%), Gaps = 5/93 (5%)
Query: 163 ARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVW-EAFKVSLSSLCSCE 221
A+ L D SDP+++L + D + + +T+ +++ LNP W E+F L +
Sbjct: 180 AKNLIPMDPNGLSDPYVKLKLIPDPKN-ESKQKTKTIRSTLNPQWNESFTFKLKP---SD 235
Query: 222 ETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQK 254
+ R L +WD+D ++DF+G S E+ K
Sbjct: 236 KDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMK 268
Score = 30.8 bits (68), Expect = 3.4
Identities = 22/92 (23%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Query: 31 RHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVFSKVFTVDYY-FEEVQRL 89
++L+ DP SDP V L + +T+ +RS+L+P +++ FT ++ +RL
Sbjct: 181 KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL 240
Query: 90 RFEVYDTHGPSGFSCQEDDFLGGMECTLGQIV 121
E++D + +DF+G + + +++
Sbjct: 241 SVEIWDWDRTT-----RNDFMGSLSFGVSELM 267
>gi|209447073 synaptotagmin I [Homo sapiens]
Length = 422
Score = 43.9 bits (102), Expect = 4e-04
Identities = 31/96 (32%), Positives = 49/96 (51%), Gaps = 10/96 (10%)
Query: 153 NNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWE---A 209
NN + +A +L D+ SDP+++++ + D + + T+V + LNPV+
Sbjct: 156 NNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKK---FETKVHRKTLNPVFNEQFT 212
Query: 210 FKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGEF 245
FKV S L + L V+D+D KHD IGEF
Sbjct: 213 FKVPYSELGG----KTLVMAVYDFDRFSKHDIIGEF 244
Score = 43.5 bits (101), Expect = 5e-04
Identities = 49/206 (23%), Positives = 90/206 (43%), Gaps = 48/206 (23%)
Query: 62 TEVVRSSLHPVFSKVFTVDYYFEEV--QRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ 119
T+V R +L+PVF++ FT + E+ + L VYD S + D +G + +
Sbjct: 196 TKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFS-----KHDIIGEFKVPMNT 250
Query: 120 I-------------VAQKKVTRPL-----LLKFGRNAGKSTITVIAEDISGNNGYVELSF 161
+ A+K+ L L++ AGK T+ ++
Sbjct: 251 VDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVIL--------------- 295
Query: 162 RARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWE---AFKVSLSSLC 218
A+ L D+ SDP+++++ + + + L+ +T + KN LNP + +F+V +
Sbjct: 296 EAKNLKKMDVGGLSDPYVKIHLMQNGKRLK-KKKTTIKKNTLNPYYNESFSFEVPFEQIQ 354
Query: 219 SCEETRPLKCLVWDYDSRGKHDFIGE 244
+ + V DYD GK+D IG+
Sbjct: 355 KVQ----VVVTVLDYDKIGKNDAIGK 376
Score = 33.5 bits (75), Expect = 0.53
Identities = 19/76 (25%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Query: 19 PCASKVELR-LSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVFSKVF 77
P A K+ + L ++L D SDP V + G+ ++ +T + +++L+P +++ F
Sbjct: 285 PTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESF 344
Query: 78 TVDYYFEEVQRLRFEV 93
+ + FE++Q+++ V
Sbjct: 345 SFEVPFEQIQKVQVVV 360
>gi|5032139 synaptotagmin I [Homo sapiens]
Length = 422
Score = 43.9 bits (102), Expect = 4e-04
Identities = 31/96 (32%), Positives = 49/96 (51%), Gaps = 10/96 (10%)
Query: 153 NNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWE---A 209
NN + +A +L D+ SDP+++++ + D + + T+V + LNPV+
Sbjct: 156 NNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKK---FETKVHRKTLNPVFNEQFT 212
Query: 210 FKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGEF 245
FKV S L + L V+D+D KHD IGEF
Sbjct: 213 FKVPYSELGG----KTLVMAVYDFDRFSKHDIIGEF 244
Score = 43.5 bits (101), Expect = 5e-04
Identities = 49/206 (23%), Positives = 90/206 (43%), Gaps = 48/206 (23%)
Query: 62 TEVVRSSLHPVFSKVFTVDYYFEEV--QRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ 119
T+V R +L+PVF++ FT + E+ + L VYD S + D +G + +
Sbjct: 196 TKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFS-----KHDIIGEFKVPMNT 250
Query: 120 I-------------VAQKKVTRPL-----LLKFGRNAGKSTITVIAEDISGNNGYVELSF 161
+ A+K+ L L++ AGK T+ ++
Sbjct: 251 VDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVIL--------------- 295
Query: 162 RARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWE---AFKVSLSSLC 218
A+ L D+ SDP+++++ + + + L+ +T + KN LNP + +F+V +
Sbjct: 296 EAKNLKKMDVGGLSDPYVKIHLMQNGKRLK-KKKTTIKKNTLNPYYNESFSFEVPFEQIQ 354
Query: 219 SCEETRPLKCLVWDYDSRGKHDFIGE 244
+ + V DYD GK+D IG+
Sbjct: 355 KVQ----VVVTVLDYDKIGKNDAIGK 376
Score = 33.5 bits (75), Expect = 0.53
Identities = 19/76 (25%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Query: 19 PCASKVELR-LSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVFSKVF 77
P A K+ + L ++L D SDP V + G+ ++ +T + +++L+P +++ F
Sbjct: 285 PTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESF 344
Query: 78 TVDYYFEEVQRLRFEV 93
+ + FE++Q+++ V
Sbjct: 345 SFEVPFEQIQKVQVVV 360
>gi|209447070 synaptotagmin I [Homo sapiens]
Length = 422
Score = 43.9 bits (102), Expect = 4e-04
Identities = 31/96 (32%), Positives = 49/96 (51%), Gaps = 10/96 (10%)
Query: 153 NNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWE---A 209
NN + +A +L D+ SDP+++++ + D + + T+V + LNPV+
Sbjct: 156 NNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKK---FETKVHRKTLNPVFNEQFT 212
Query: 210 FKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGEF 245
FKV S L + L V+D+D KHD IGEF
Sbjct: 213 FKVPYSELGG----KTLVMAVYDFDRFSKHDIIGEF 244
Score = 43.5 bits (101), Expect = 5e-04
Identities = 49/206 (23%), Positives = 90/206 (43%), Gaps = 48/206 (23%)
Query: 62 TEVVRSSLHPVFSKVFTVDYYFEEV--QRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ 119
T+V R +L+PVF++ FT + E+ + L VYD S + D +G + +
Sbjct: 196 TKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFS-----KHDIIGEFKVPMNT 250
Query: 120 I-------------VAQKKVTRPL-----LLKFGRNAGKSTITVIAEDISGNNGYVELSF 161
+ A+K+ L L++ AGK T+ ++
Sbjct: 251 VDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVIL--------------- 295
Query: 162 RARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWE---AFKVSLSSLC 218
A+ L D+ SDP+++++ + + + L+ +T + KN LNP + +F+V +
Sbjct: 296 EAKNLKKMDVGGLSDPYVKIHLMQNGKRLK-KKKTTIKKNTLNPYYNESFSFEVPFEQIQ 354
Query: 219 SCEETRPLKCLVWDYDSRGKHDFIGE 244
+ + V DYD GK+D IG+
Sbjct: 355 KVQ----VVVTVLDYDKIGKNDAIGK 376
Score = 33.5 bits (75), Expect = 0.53
Identities = 19/76 (25%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Query: 19 PCASKVELR-LSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVFSKVF 77
P A K+ + L ++L D SDP V + G+ ++ +T + +++L+P +++ F
Sbjct: 285 PTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESF 344
Query: 78 TVDYYFEEVQRLRFEV 93
+ + FE++Q+++ V
Sbjct: 345 SFEVPFEQIQKVQVVV 360
>gi|238550198 synaptotagmin III [Homo sapiens]
Length = 590
Score = 43.5 bits (101), Expect = 5e-04
Identities = 53/207 (25%), Positives = 87/207 (42%), Gaps = 49/207 (23%)
Query: 61 RTEVVRSSLHPVFSKVFTVDYYFEEV--QRLRFEVYDTHGPSGFSCQEDDFLGGMECTLG 118
+T+V R +L+PVF++ F E+ ++L F VYD S D +G +
Sbjct: 352 QTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFS-----RHDLIGQVVLDNL 406
Query: 119 QIVAQKKVTRPL-------------------LLKFGRNAGKSTITVIAEDISGNNGYVEL 159
+A++ RPL L + AG+ T+T+I
Sbjct: 407 LELAEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTAGRLTVTII------------- 453
Query: 160 SFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWE---AFKVSLSS 216
+A L DL SDP+++ +++ + L+ +T + KN LNP + F V+ S
Sbjct: 454 --KASNLKAMDLTGFSDPYVKASLISEGRRLK-KRKTSIKKNTLNPTYNEALVFDVAPES 510
Query: 217 LCSCEETRPLKCLVWDYDSRGKHDFIG 243
+ E L V DYD G ++ IG
Sbjct: 511 V----ENVGLSIAVVDYDCIGHNEVIG 533
Score = 42.0 bits (97), Expect = 0.001
Identities = 33/113 (29%), Positives = 54/113 (47%), Gaps = 10/113 (8%)
Query: 135 GRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVY 194
G A I+ + G++ V +A L KD SDP++++Y + D + +
Sbjct: 295 GTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKK---F 351
Query: 195 RTEVVKNNLNPVWEA---FKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGE 244
+T+V + LNPV+ F V L+ L R L V+D+D +HD IG+
Sbjct: 352 QTKVHRKTLNPVFNETFQFSVPLAELAQ----RKLHFSVYDFDRFSRHDLIGQ 400
>gi|238550196 synaptotagmin III [Homo sapiens]
Length = 590
Score = 43.5 bits (101), Expect = 5e-04
Identities = 53/207 (25%), Positives = 87/207 (42%), Gaps = 49/207 (23%)
Query: 61 RTEVVRSSLHPVFSKVFTVDYYFEEV--QRLRFEVYDTHGPSGFSCQEDDFLGGMECTLG 118
+T+V R +L+PVF++ F E+ ++L F VYD S D +G +
Sbjct: 352 QTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFS-----RHDLIGQVVLDNL 406
Query: 119 QIVAQKKVTRPL-------------------LLKFGRNAGKSTITVIAEDISGNNGYVEL 159
+A++ RPL L + AG+ T+T+I
Sbjct: 407 LELAEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTAGRLTVTII------------- 453
Query: 160 SFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWE---AFKVSLSS 216
+A L DL SDP+++ +++ + L+ +T + KN LNP + F V+ S
Sbjct: 454 --KASNLKAMDLTGFSDPYVKASLISEGRRLK-KRKTSIKKNTLNPTYNEALVFDVAPES 510
Query: 217 LCSCEETRPLKCLVWDYDSRGKHDFIG 243
+ E L V DYD G ++ IG
Sbjct: 511 V----ENVGLSIAVVDYDCIGHNEVIG 533
Score = 42.0 bits (97), Expect = 0.001
Identities = 33/113 (29%), Positives = 54/113 (47%), Gaps = 10/113 (8%)
Query: 135 GRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVY 194
G A I+ + G++ V +A L KD SDP++++Y + D + +
Sbjct: 295 GTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKK---F 351
Query: 195 RTEVVKNNLNPVWEA---FKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGE 244
+T+V + LNPV+ F V L+ L R L V+D+D +HD IG+
Sbjct: 352 QTKVHRKTLNPVFNETFQFSVPLAELAQ----RKLHFSVYDFDRFSRHDLIGQ 400
>gi|14150054 synaptotagmin III [Homo sapiens]
Length = 590
Score = 43.5 bits (101), Expect = 5e-04
Identities = 53/207 (25%), Positives = 87/207 (42%), Gaps = 49/207 (23%)
Query: 61 RTEVVRSSLHPVFSKVFTVDYYFEEV--QRLRFEVYDTHGPSGFSCQEDDFLGGMECTLG 118
+T+V R +L+PVF++ F E+ ++L F VYD S D +G +
Sbjct: 352 QTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFS-----RHDLIGQVVLDNL 406
Query: 119 QIVAQKKVTRPL-------------------LLKFGRNAGKSTITVIAEDISGNNGYVEL 159
+A++ RPL L + AG+ T+T+I
Sbjct: 407 LELAEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTAGRLTVTII------------- 453
Query: 160 SFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWE---AFKVSLSS 216
+A L DL SDP+++ +++ + L+ +T + KN LNP + F V+ S
Sbjct: 454 --KASNLKAMDLTGFSDPYVKASLISEGRRLK-KRKTSIKKNTLNPTYNEALVFDVAPES 510
Query: 217 LCSCEETRPLKCLVWDYDSRGKHDFIG 243
+ E L V DYD G ++ IG
Sbjct: 511 V----ENVGLSIAVVDYDCIGHNEVIG 533
Score = 42.0 bits (97), Expect = 0.001
Identities = 33/113 (29%), Positives = 54/113 (47%), Gaps = 10/113 (8%)
Query: 135 GRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVY 194
G A I+ + G++ V +A L KD SDP++++Y + D + +
Sbjct: 295 GTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKK---F 351
Query: 195 RTEVVKNNLNPVWEA---FKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGE 244
+T+V + LNPV+ F V L+ L R L V+D+D +HD IG+
Sbjct: 352 QTKVHRKTLNPVFNETFQFSVPLAELAQ----RKLHFSVYDFDRFSRHDLIGQ 400
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,034,327
Number of Sequences: 37866
Number of extensions: 982846
Number of successful extensions: 2592
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 91
Number of HSP's that attempted gapping in prelim test: 2258
Number of HSP's gapped (non-prelim): 284
length of query: 558
length of database: 18,247,518
effective HSP length: 107
effective length of query: 451
effective length of database: 14,195,856
effective search space: 6402331056
effective search space used: 6402331056
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.