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Search of human proteins with 120431738
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|120431738 huntingtin-associated protein 1 isoform 2 [Homo
sapiens]
(619 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|120431738 huntingtin-associated protein 1 isoform 2 [Homo sap... 1228 0.0
gi|120431745 huntingtin-associated protein 1 isoform 4 [Homo sap... 1167 0.0
gi|120431743 huntingtin-associated protein 1 isoform 3 [Homo sap... 1160 0.0
gi|45359873 OGT(O-Glc-NAc transferase)-interacting protein 106 K... 145 8e-35
gi|111074532 OGT(O-Glc-NAc transferase)-interacting protein 106 ... 141 2e-33
gi|188497667 trafficking protein, kinesin binding 2 [Homo sapiens] 127 3e-29
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 72 2e-12
gi|221139761 zinc finger protein 853 [Homo sapiens] 64 3e-10
gi|148746195 trichohyalin [Homo sapiens] 64 4e-10
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 62 1e-09
gi|38569484 kinesin family member 21A [Homo sapiens] 62 1e-09
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 62 2e-09
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 62 2e-09
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 62 2e-09
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 61 3e-09
gi|126723390 ankyrin repeat domain 24 [Homo sapiens] 61 3e-09
gi|44890059 involucrin [Homo sapiens] 60 5e-09
gi|14165274 golgi-associated microtubule-binding protein HOOK3 [... 60 8e-09
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 59 1e-08
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 59 1e-08
gi|119120918 coiled-coil domain containing 64 [Homo sapiens] 59 1e-08
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 59 2e-08
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 59 2e-08
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 59 2e-08
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 59 2e-08
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 57 4e-08
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 57 4e-08
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 57 5e-08
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 57 5e-08
gi|217272804 hyaluronan-mediated motility receptor isoform d [Ho... 56 9e-08
>gi|120431738 huntingtin-associated protein 1 isoform 2 [Homo
sapiens]
Length = 619
Score = 1228 bits (3177), Expect = 0.0
Identities = 619/619 (100%), Positives = 619/619 (100%)
Query: 1 MRPKRLGRCCAGSRLGPGDPAALTCAPSPSASPAPEPSAQPQARGTGQRVGSRATSGSQF 60
MRPKRLGRCCAGSRLGPGDPAALTCAPSPSASPAPEPSAQPQARGTGQRVGSRATSGSQF
Sbjct: 1 MRPKRLGRCCAGSRLGPGDPAALTCAPSPSASPAPEPSAQPQARGTGQRVGSRATSGSQF 60
Query: 61 LSEARTGARPASEAGAKAGARRPSAFSAIQGDVRSMPDNSDAPWTRFVFQGPFGSRATGR 120
LSEARTGARPASEAGAKAGARRPSAFSAIQGDVRSMPDNSDAPWTRFVFQGPFGSRATGR
Sbjct: 61 LSEARTGARPASEAGAKAGARRPSAFSAIQGDVRSMPDNSDAPWTRFVFQGPFGSRATGR 120
Query: 121 GTGKAAGIWKTPAAYVGRRPGVSGPERAAFIRELEEALCPNLPPPVKKITQEDVKVMLYL 180
GTGKAAGIWKTPAAYVGRRPGVSGPERAAFIRELEEALCPNLPPPVKKITQEDVKVMLYL
Sbjct: 121 GTGKAAGIWKTPAAYVGRRPGVSGPERAAFIRELEEALCPNLPPPVKKITQEDVKVMLYL 180
Query: 181 LEELLPPVWESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEIL 240
LEELLPPVWESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEIL
Sbjct: 181 LEELLPPVWESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEIL 240
Query: 241 YLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLI 300
YLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLI
Sbjct: 241 YLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLI 300
Query: 301 SQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEAS 360
SQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEAS
Sbjct: 301 SQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEAS 360
Query: 361 QQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQM 420
QQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQM
Sbjct: 361 QQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQM 420
Query: 421 QLQEEETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQ 480
QLQEEETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQ
Sbjct: 421 QLQEEETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQ 480
Query: 481 VRGFEAEEGLMLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGW 540
VRGFEAEEGLMLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGW
Sbjct: 481 VRGFEAEEGLMLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGW 540
Query: 541 EEVELELDEATRMNVVTSALEASGLGPSHLDMNYVLQQLANWQDAHYRRQLRWKMLQKGE 600
EEVELELDEATRMNVVTSALEASGLGPSHLDMNYVLQQLANWQDAHYRRQLRWKMLQKGE
Sbjct: 541 EEVELELDEATRMNVVTSALEASGLGPSHLDMNYVLQQLANWQDAHYRRQLRWKMLQKGE 600
Query: 601 CPHGALPAASRTSCRSSCR 619
CPHGALPAASRTSCRSSCR
Sbjct: 601 CPHGALPAASRTSCRSSCR 619
>gi|120431745 huntingtin-associated protein 1 isoform 4 [Homo
sapiens]
Length = 594
Score = 1167 bits (3020), Expect = 0.0
Identities = 594/619 (95%), Positives = 594/619 (95%), Gaps = 25/619 (4%)
Query: 1 MRPKRLGRCCAGSRLGPGDPAALTCAPSPSASPAPEPSAQPQARGTGQRVGSRATSGSQF 60
MRPKRLGRCCAGSRLGPGDPAALTCAPSPSASPAPEPSAQPQARGTGQRVGSRATSGSQF
Sbjct: 1 MRPKRLGRCCAGSRLGPGDPAALTCAPSPSASPAPEPSAQPQARGTGQRVGSRATSGSQF 60
Query: 61 LSEARTGARPASEAGAKAGARRPSAFSAIQGDVRSMPDNSDAPWTRFVFQGPFGSRATGR 120
LSEARTGARPASEAGAKAGARRPSAFSAIQGDVRSMPDNSDAPWTRFVFQGPFGSRATGR
Sbjct: 61 LSEARTGARPASEAGAKAGARRPSAFSAIQGDVRSMPDNSDAPWTRFVFQGPFGSRATGR 120
Query: 121 GTGKAAGIWKTPAAYVGRRPGVSGPERAAFIRELEEALCPNLPPPVKKITQEDVKVMLYL 180
GTGKAAGIWKTPAAYVGRRPGVSGPERAAFIRELEEALCPNLPPPVKKITQEDVKVMLYL
Sbjct: 121 GTGKAAGIWKTPAAYVGRRPGVSGPERAAFIRELEEALCPNLPPPVKKITQEDVKVMLYL 180
Query: 181 LEELLPPVWESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEIL 240
LEELLPPVWESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEIL
Sbjct: 181 LEELLPPVWESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEIL 240
Query: 241 YLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLI 300
YLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLI
Sbjct: 241 YLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLI 300
Query: 301 SQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEAS 360
SQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEAS
Sbjct: 301 SQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEAS 360
Query: 361 QQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQM 420
QQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRM
Sbjct: 361 QQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRM-------------------- 400
Query: 421 QLQEEETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQ 480
ETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQ
Sbjct: 401 -----ETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQ 455
Query: 481 VRGFEAEEGLMLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGW 540
VRGFEAEEGLMLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGW
Sbjct: 456 VRGFEAEEGLMLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGW 515
Query: 541 EEVELELDEATRMNVVTSALEASGLGPSHLDMNYVLQQLANWQDAHYRRQLRWKMLQKGE 600
EEVELELDEATRMNVVTSALEASGLGPSHLDMNYVLQQLANWQDAHYRRQLRWKMLQKGE
Sbjct: 516 EEVELELDEATRMNVVTSALEASGLGPSHLDMNYVLQQLANWQDAHYRRQLRWKMLQKGE 575
Query: 601 CPHGALPAASRTSCRSSCR 619
CPHGALPAASRTSCRSSCR
Sbjct: 576 CPHGALPAASRTSCRSSCR 594
>gi|120431743 huntingtin-associated protein 1 isoform 3 [Homo
sapiens]
Length = 602
Score = 1160 bits (3001), Expect = 0.0
Identities = 594/627 (94%), Positives = 594/627 (94%), Gaps = 33/627 (5%)
Query: 1 MRPKRLGRCCAGSRLGPGDPAALTCAPSPSASPAPEPSAQPQARGTGQRVGSRATSGSQF 60
MRPKRLGRCCAGSRLGPGDPAALTCAPSPSASPAPEPSAQPQARGTGQRVGSRATSGSQF
Sbjct: 1 MRPKRLGRCCAGSRLGPGDPAALTCAPSPSASPAPEPSAQPQARGTGQRVGSRATSGSQF 60
Query: 61 LSEARTGARPASEAGAKAGARRPSAFSAIQGDVRSMPDNSDAPWTRFVFQGPFGSRATGR 120
LSEARTGARPASEAGAKAGARRPSAFSAIQGDVRSMPDNSDAPWTRFVFQGPFGSRATGR
Sbjct: 61 LSEARTGARPASEAGAKAGARRPSAFSAIQGDVRSMPDNSDAPWTRFVFQGPFGSRATGR 120
Query: 121 GTGKAAGIWKTPAAYVGRRPGVSGPERAAFIRELEEALCPNLPPPVKKITQEDVKVMLYL 180
GTGKAAGIWKTPAAYVGRRPGVSGPERAAFIRELEEALCPNLPPPVKKITQEDVKVMLYL
Sbjct: 121 GTGKAAGIWKTPAAYVGRRPGVSGPERAAFIRELEEALCPNLPPPVKKITQEDVKVMLYL 180
Query: 181 LEE--------LLPPVWESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALL 232
LEE LLPPVWESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALL
Sbjct: 181 LEEVCTAFLIQLLPPVWESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALL 240
Query: 233 GSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAH 292
GSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAH
Sbjct: 241 GSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAH 300
Query: 293 PCDAPKLISQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILEC 352
PCDAPKLISQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILEC
Sbjct: 301 PCDAPKLISQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILEC 360
Query: 353 VEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQL 412
VEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRM
Sbjct: 361 VEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRM------------ 408
Query: 413 ASEKEIQMQLQEEETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDF 472
ETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDF
Sbjct: 409 -------------ETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDF 455
Query: 473 RYSEDREQVRGFEAEEGLMLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAEL 532
RYSEDREQVRGFEAEEGLMLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAEL
Sbjct: 456 RYSEDREQVRGFEAEEGLMLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAEL 515
Query: 533 VSEETEGWEEVELELDEATRMNVVTSALEASGLGPSHLDMNYVLQQLANWQDAHYRRQLR 592
VSEETEGWEEVELELDEATRMNVVTSALEASGLGPSHLDMNYVLQQLANWQDAHYRRQLR
Sbjct: 516 VSEETEGWEEVELELDEATRMNVVTSALEASGLGPSHLDMNYVLQQLANWQDAHYRRQLR 575
Query: 593 WKMLQKGECPHGALPAASRTSCRSSCR 619
WKMLQKGECPHGALPAASRTSCRSSCR
Sbjct: 576 WKMLQKGECPHGALPAASRTSCRSSCR 602
>gi|45359873 OGT(O-Glc-NAc transferase)-interacting protein 106 KDa
isoform 2 [Homo sapiens]
Length = 686
Score = 145 bits (367), Expect = 8e-35
Identities = 110/327 (33%), Positives = 166/327 (50%), Gaps = 66/327 (20%)
Query: 154 LEEALCPNLPPPVKKITQEDVKVMLYLLEELLPPVWESVTYGMVLQRERDLNTAARIGQS 213
LEE LC + K T D+ + LLEE +ERDL AARIGQS
Sbjct: 35 LEEVLCAERVGQMTK-TYNDIDAVTRLLEE----------------KERDLELAARIGQS 77
Query: 214 LVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEK 273
L+K+N L E N LE + +EE+ LRH+++++DELLQ Y+ + EE E E
Sbjct: 78 LLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPES------ 131
Query: 274 EAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLEEENHQLRE 333
C P ++ + Q++ L++LQ+KL+ LEEEN LR
Sbjct: 132 -------------------VCSTPLKRNESSSSVQNYF-HLDSLQKKLKDLEEENVVLRS 171
Query: 334 EASQLD----TLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQA 389
EASQL T E++EQ L+ +CV++ +A+ Q+A +SE L + E+ RQQ+E+ L +
Sbjct: 172 EASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLS 231
Query: 390 QVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPGFQETLAE------ELRTSL 443
Q++ LQ++ + E E+L + L + K+ Q QL E L ++ AE E + L
Sbjct: 232 QIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAE--LRELEDKYAECMEMLHEAQEEL 289
Query: 444 RRMISDPVYFMERNYEMPRGDTSSLRY 470
+ + RN MP +T+S RY
Sbjct: 290 KNL---------RNKTMP--NTTSRRY 305
>gi|111074532 OGT(O-Glc-NAc transferase)-interacting protein 106 KDa
isoform 1 [Homo sapiens]
Length = 953
Score = 141 bits (356), Expect = 2e-33
Identities = 98/282 (34%), Positives = 152/282 (53%), Gaps = 49/282 (17%)
Query: 199 QRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSD 258
++ERDL AARIGQSL+K+N L E N LE + +EE+ LRH+++++DELLQ Y+
Sbjct: 121 EKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTS 180
Query: 259 SDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQ 318
+ EE E E C P ++ + Q++ L++LQ
Sbjct: 181 AAEESEPES-------------------------VCSTPLKRNESSSSVQNYF-HLDSLQ 214
Query: 319 EKLRLLEEENHQLREEASQLD----TLEDEEQMLILECVEQFSEASQQMAELSEVLVLRL 374
+KL+ LEEEN LR EASQL T E++EQ L+ +CV++ +A+ Q+A +SE L +
Sbjct: 215 KKLKDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKT 274
Query: 375 ENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPGFQET 434
E+ RQQ+E+ L +Q++ LQ++ + E E+L + L + K+ Q QL E L ++
Sbjct: 275 EDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAE--LRELEDK 332
Query: 435 LAE------ELRTSLRRMISDPVYFMERNYEMPRGDTSSLRY 470
AE E + L+ + RN MP +T+S RY
Sbjct: 333 YAECMEMLHEAQEELKNL---------RNKTMP--NTTSRRY 363
>gi|188497667 trafficking protein, kinesin binding 2 [Homo sapiens]
Length = 914
Score = 127 bits (319), Expect = 3e-29
Identities = 80/234 (34%), Positives = 129/234 (55%), Gaps = 30/234 (12%)
Query: 196 MVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQL 255
++ +R+RDL AARIGQ+L+K+N VL E+N LE LG A +++ L+H++ +DELL++
Sbjct: 118 LLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRI 177
Query: 256 YSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLE 315
S + EE E + C P ++ L Q QLE
Sbjct: 178 VSIASEESETDSS-------------------------CSTPLRFNESFSLSQ-GLLQLE 211
Query: 316 ALQEKLRLLEEENHQLREEASQLD----TLEDEEQMLILECVEQFSEASQQMAELSEVLV 371
LQEKL+ LEEEN LR +A + T E++EQ L+ +CV++ E + QM+ ++E L
Sbjct: 212 MLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELS 271
Query: 372 LRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEE 425
+ + R Q+E++ L +Q++ LQ + + + E E+L+ L + K+ Q QL E
Sbjct: 272 GKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTME 325
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 72.0 bits (175), Expect = 2e-12
Identities = 57/229 (24%), Positives = 115/229 (50%), Gaps = 15/229 (6%)
Query: 223 EENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEE 282
E+ K E +G +E++ Q+ ++E +Q + ++ E++ ++EE+ E+E++
Sbjct: 213 EQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMR 272
Query: 283 EAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLE 342
E EE Q + + Q + Q E ++E+ + E+ Q+RE+ Q+ +
Sbjct: 273 EQEE--QMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMG--K 328
Query: 343 DEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYG 402
EEQM E EQ E +QM + E + + E ++Q+++V + + Q+ K +++ R
Sbjct: 329 QEEQMW--EQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQE 386
Query: 403 AETEKLQKQLASEKEIQM-----QLQEEETLPGFQETLAEELRTSLRRM 446
+ K ++Q+ +KE QM Q++E+E G Q+ E++R M
Sbjct: 387 EQMRKQEEQMGEQKE-QMGEQKEQMREQEEQMGEQK---EQMRKQEEHM 431
Score = 70.5 bits (171), Expect = 4e-12
Identities = 54/234 (23%), Positives = 116/234 (49%), Gaps = 12/234 (5%)
Query: 200 RERDLNTAARIGQSLVKQNSVLMEENS--KLEALLGSAKEEILYLRHQVNLRDELL---- 253
RE++ + GQ ++ V +E + E +G +E++ Q+ ++E +
Sbjct: 167 REQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQE 226
Query: 254 -QLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCP 312
Q+ ++ E EE+ ++++E ++QEE+ +++ Q + + ++ L +
Sbjct: 227 EQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTE 286
Query: 313 QLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVL 372
Q E E+ + E+ Q+RE+ Q+ E EEQM E EQ + +QM E E +
Sbjct: 287 QEEQTGEQEEQMREQEEQMREQEEQM--REQEEQM--REQEEQMGKQEEQMWEQKEQMWE 342
Query: 373 RLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEE 426
+ E +Q++++ + Q+ K +++ R + K ++Q+ ++E QM+ QEE+
Sbjct: 343 QKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEE-QMRKQEEQ 395
Score = 62.4 bits (150), Expect = 1e-09
Identities = 82/372 (22%), Positives = 165/372 (44%), Gaps = 36/372 (9%)
Query: 200 RERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVN-LRDELLQLYSD 258
RE++ + GQ + +Q + E+ ++ G +E+ +R Q +R++ Q+
Sbjct: 62 REQEGQVREQEGQ-VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 120
Query: 259 SDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQ 318
+ E E + E++ EQE + E++ Q ++ QE + + Q ++
Sbjct: 121 EGQVREQEGQVREQEGQVREQEGQVREQEGQVRE--QEGQVREQEGQVRE----QEGQVR 174
Query: 319 EKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYE 378
E+ + E+ Q+RE+ Q+ E E QM E EQ E +QM + E + + E
Sbjct: 175 EQEGQVREQEGQVREQEGQMG--EQEGQMGEQE--EQMGEQEEQMQKQEEQMGEQEEQMR 230
Query: 379 RQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPGFQETLAEE 438
+Q++++ + QV K +++ + + K ++Q+ ++E QM+ QEE+ L ++T EE
Sbjct: 231 KQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEE-QMREQEEQMLKQKEQTEQEE 289
Query: 439 --------LRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAEEGL 490
+R +M E+ +M + + + + E +EQ+ +E +E +
Sbjct: 290 QTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQM--WEQKEQM 347
Query: 491 MLAADIM--RGEDFTPAEEFVPQEELGAAKKV-----------PAEEGVMEEAELVSEET 537
+ M + E EE V ++E K+ EE + E+ E + E+
Sbjct: 348 WKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQK 407
Query: 538 EGWEEVELELDE 549
E E E ++ E
Sbjct: 408 EQMREQEEQMGE 419
Score = 49.7 bits (117), Expect = 8e-06
Identities = 78/381 (20%), Positives = 162/381 (42%), Gaps = 35/381 (9%)
Query: 168 KITQEDVKVMLYLLEELLPPVWESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENSK 227
+IT E++K L+E L V + ++L + + Q + E+ +
Sbjct: 3 RITNEELKEKNAELQEELQLV--ETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQ 60
Query: 228 LEALLGSAKEEILYLRHQVN-LRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEE 286
+ G +E+ +R Q +R++ Q+ + E E + E++ EQE + E+
Sbjct: 61 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 120
Query: 287 DLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQ 346
+ Q QE + + Q ++E+ + E+ Q+RE+ Q+ E + +
Sbjct: 121 EGQVRE---------QEGQVRE----QEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 167
Query: 347 MLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETE 406
+ EQ + +Q ++ E E + ++ ++ Q ++Q++ G + E
Sbjct: 168 EQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEE 227
Query: 407 KLQKQ--LASEKEIQMQLQEEETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGD 464
+++KQ E+E Q+Q QEE+ + E++R +M E+ +M +
Sbjct: 228 QMRKQEEQMGEQEEQVQKQEEQV-----QKQEEQMRKQEEQMREQEEQMREQEEQMLK-Q 281
Query: 465 TSSLRYDFRYSEDREQVRGFEAEEGLMLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEE 524
+ + E EQ+R E EE + + MR ++ E+ +E++G EE
Sbjct: 282 KEQTEQEEQTGEQEEQMR--EQEEQMREQEEQMREQEEQMREQ---EEQMG-----KQEE 331
Query: 525 GVMEEAELVSEETEG-WEEVE 544
+ E+ E + E+ E W++ E
Sbjct: 332 QMWEQKEQMWEQKEQMWKQEE 352
Score = 42.4 bits (98), Expect = 0.001
Identities = 38/174 (21%), Positives = 84/174 (48%), Gaps = 19/174 (10%)
Query: 216 KQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEA 275
++ + +E ++ E G +E++ Q+ ++E ++ E++E E+EE+
Sbjct: 275 EEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMR------EQEEQMREQEEQMGK 328
Query: 276 EEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLEEE----NHQL 331
+EEQ E+ E+ + ++ QE + + Q++ +E++R EE+ Q+
Sbjct: 329 QEEQMWEQKEQMWE-----QKEQMWKQEEQMGEQE-EQMQKQEEQVRKQEEQMRKQEEQM 382
Query: 332 REEASQLDTLED---EEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQ 382
R++ Q+ E+ E++ + E EQ E +QM E E + + E+ Q++
Sbjct: 383 RKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 35.0 bits (79), Expect = 0.20
Identities = 30/149 (20%), Positives = 70/149 (46%), Gaps = 8/149 (5%)
Query: 199 QRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSD 258
Q E++ T + Q ++ + +E E ++E + + + ++ Q++
Sbjct: 284 QTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQ 343
Query: 259 SDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQ 318
++ + EE+ E++E ++QEE+ +++ Q ++ QE + + Q E +
Sbjct: 344 KEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRK--QEEQMRKQEEQMRK----QEEQMG 397
Query: 319 EKLRLLEEENHQLREEASQLDTLEDEEQM 347
E+ + E+ Q+RE+ Q+ E +EQM
Sbjct: 398 EQKEQMGEQKEQMREQEEQMG--EQKEQM 424
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 64.3 bits (155), Expect = 3e-10
Identities = 51/219 (23%), Positives = 105/219 (47%), Gaps = 10/219 (4%)
Query: 244 HQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQE 303
H L+ EL ++ + + +E++ ++ +E+ + ++A+E + + ++
Sbjct: 142 HHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQ 201
Query: 304 ALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSE--ASQ 361
LL Q Q E LQ++ L ++E Q ++ Q + L+ ++Q+L+L+ Q + Q
Sbjct: 202 QLLQQ----QQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQ 257
Query: 362 QMAELSEVLVLRLENYERQ-QQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQM 420
Q A+L + L LE + Q QQ++ Q + L+ QQ+ ++ + E+LQ+Q ++
Sbjct: 258 QQAQLQQQL---LEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEP 314
Query: 421 QLQEEETLPGFQETLAEELRTSLRRMISDPVYFMERNYE 459
+ +EE L L E +R + +ER E
Sbjct: 315 EEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQE 353
Score = 50.8 bits (120), Expect = 4e-06
Identities = 67/323 (20%), Positives = 137/323 (42%), Gaps = 47/323 (14%)
Query: 257 SDSDEEDEDEEEE------------------EEEKEAEEEQEEEEAEEDLQCAHPCDAPK 298
S+S EE+E +E EE + + E + ++ E+ + +
Sbjct: 49 SESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQHEQ 108
Query: 299 LISQEALLHQHHCPQLEALQEKLRLLEEENH------------QLREEASQLDTLEDEEQ 346
L + L PQ + Q++L L++E H QL + QL + +EQ
Sbjct: 109 LQQPQPHLELQQQPQQDG-QQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQ 167
Query: 347 MLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETE 406
+ + EQ Q A+ +VL + E ++Q QE LQ Q +LQQ+ + + E
Sbjct: 168 QRLQQQQEQL---QTQQAQEQQVL-QQQEQLQQQVQEQQLLQQQQEQLQQQQLL--QQQE 221
Query: 407 KLQKQLASEKEIQMQLQEEETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTS 466
+LQ+Q +++ Q+Q Q++ L Q L ++L + + + ++ +
Sbjct: 222 QLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQ---------A 272
Query: 467 SLRYDFRYSEDREQVRGFEAEEGLMLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGV 526
L+ + +EQ++ + ++ L + ++ + P +EE + +P + G
Sbjct: 273 QLQQQL-LLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGS 331
Query: 527 MEEAELVSEETEGWEEVELELDE 549
+E E +E E +E+E + ++
Sbjct: 332 EQELEQQRQELERQQELERQQEQ 354
Score = 50.1 bits (118), Expect = 6e-06
Identities = 70/341 (20%), Positives = 147/341 (43%), Gaps = 57/341 (16%)
Query: 138 RRPGVSGPERAAFI--------RELEEALCPNLPPPVKKITQEDVKVMLYLLEELLPPVW 189
+RP VS P A+ I REL+ P P ++ E ++ LE P
Sbjct: 65 QRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQ 124
Query: 190 ESVTYGMVLQRERD--------------LNTAARIGQSLVKQNSVLMEENSKLEALLGSA 235
+ LQ+E+ ++ ++ V++ L ++ +L+
Sbjct: 125 DGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQ- 183
Query: 236 KEEILYLRHQVNLRDELLQLYSDSDEEDEDEE---EEEEEKEAEEEQEEEEAEED----- 287
++++L + Q+ + + QL E+ + ++ ++E+ ++ + +Q++E+ ++
Sbjct: 184 EQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLL 243
Query: 288 LQCAHPCDAPKLISQEALLHQHHCPQLEA-LQEKL--------------RLLEEENHQLR 332
LQ L Q+A L Q Q +A LQ++L +LL+++ QL+
Sbjct: 244 LQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQ 303
Query: 333 EEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQE---VARLQA 389
++ Q LE EE+ + + S+Q E + R + ERQQ++ +LQ
Sbjct: 304 QQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQE 363
Query: 390 QVLKLQQRCRMYGAETEKLQKQL--------ASEKEIQMQL 422
++ +L+Q+ + E+ + QL A ++E+Q++L
Sbjct: 364 ELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLEL 404
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 63.9 bits (154), Expect = 4e-10
Identities = 91/359 (25%), Positives = 145/359 (40%), Gaps = 55/359 (15%)
Query: 199 QRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEE----ILYLRHQVNLRDELLQ 254
QRER L R ++ L EE K + + E L Q+ R+ Q
Sbjct: 793 QRERQLRAEER----QQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQ 848
Query: 255 LYSDSDEEDEDEEEEEEEKEAEEE------QEEEEAEEDLQCAHPCDAPKLISQEALLHQ 308
L + D ED+E +++ ++ +EE + A P +L ++ LL +
Sbjct: 849 LQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQE 908
Query: 309 HHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSE 368
+EK R E+E Q REE + L+ EE+ L
Sbjct: 909 EEEELQREEREKRRRQEQE-RQYREE----EQLQQEEEQL-------------------- 943
Query: 369 VLVLRLENYERQQQEVARLQAQVLKLQQR-CRMYGAETEKLQKQLASEKEIQMQLQEEET 427
LR E +R++QE R + KLQQ+ ++ G E EK ++Q E + + +EEE
Sbjct: 944 ---LREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQ-----EREKKYREEEE 995
Query: 428 LPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAE 487
L +E L E R RR + Y + E+ + + LR + +E+ R + E
Sbjct: 996 LQQEEEQLLREEREKRRRQEWERQY--RKKDELQQEEEQLLREEREKRRLQERERQYREE 1053
Query: 488 EGLMLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGWEEVELE 546
E L + + GE+ E ++EL + EE EE +L+ EE E E E
Sbjct: 1054 EELQQEEEQLLGEE----RETRRRQELERQYR-KEEELQQEEEQLLREEPEKRRRQERE 1107
Score = 60.5 bits (145), Expect = 5e-09
Identities = 77/315 (24%), Positives = 135/315 (42%), Gaps = 45/315 (14%)
Query: 242 LRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQ-----EEEEAEEDLQCAHPCDA 296
L+ Q+ +LLQ EE+E+ + EE EK +EQ EEE+ +++ + +
Sbjct: 895 LQEQLRKEQQLLQ------EEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREER 948
Query: 297 PKLISQEALLHQHHCPQLEALQEKLRLLEEENHQLREEAS----QLDTLEDEEQMLILEC 352
K QE +L+ +E+L L EE + R+E + + L+ EE+ L+ E
Sbjct: 949 EKRRRQERERQYRKDKKLQQKEEQL-LGEEPEKRRRQEREKKYREEEELQQEEEQLLRE- 1006
Query: 353 VEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQ--K 410
E ++ + E + + +++++++ R + + +LQ+R R Y E E Q +
Sbjct: 1007 -----EREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEE 1061
Query: 411 QLASE-------KEIQMQLQEEETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRG 463
QL E +E++ Q ++EE L +E L E RR ER +
Sbjct: 1062 QLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRR--------QERERQCREE 1113
Query: 464 DTSSLRYDFRYSEDREQVRGFEAEEGLMLAADIMRGEDFTPAEEFVPQEELGAAKKVPAE 523
+ + E+RE+ R E E E+ EE + +EE ++ E
Sbjct: 1114 EELQQEEEQLLREEREKRRRQELER------QYREEEEVQQEEEQLLREEPEKRRRQELE 1167
Query: 524 EGVMEEAELVSEETE 538
EE EL EE +
Sbjct: 1168 RQYREEEELQQEEEQ 1182
Score = 55.8 bits (133), Expect = 1e-07
Identities = 81/339 (23%), Positives = 134/339 (39%), Gaps = 74/339 (21%)
Query: 260 DEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQE 319
+EE + ++ + K +EEQ+ E Q D + +E L Q Q + QE
Sbjct: 1519 EEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQ--DRDRKFREEEQLRQEREEQQLSRQE 1576
Query: 320 KLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQ--------FSEASQQMAELSEVLV 371
+ R E ++R + + +EDE+Q+ E +Q F E Q + E E +
Sbjct: 1577 RDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQL 1636
Query: 372 LR-------------LENYERQQQ----------EVARL----QAQVLKLQQRCRMYGAE 404
R L ER+QQ E +L + Q L+ Q+R R + E
Sbjct: 1637 HRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREE 1696
Query: 405 TEKLQKQLASEK-----------EIQMQLQEEETLPGFQETLAEELRTSLRRMISDPVYF 453
++L++Q K E++ + +EEE L QET E+LR R
Sbjct: 1697 EQQLRRQERERKFLQEEQQLRRQELERKFREEEQLR--QETEQEQLRRQERYR-----KI 1749
Query: 454 MERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAEEGLMLAADIMRGEDFTPAEEFVPQEE 513
+E P + LR +E+ R F EE L + + +F +E+
Sbjct: 1750 LEEEQLRPEREEQQLR-------RQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQ 1802
Query: 514 LGAAKKVPAEEGVMEEAELVSEETEG---WEEVELELDE 549
L + EE +L ++ +G WEE +L+L+E
Sbjct: 1803 LRQER---------EEQQLRPQQRDGKYRWEEEQLQLEE 1832
Score = 55.5 bits (132), Expect = 1e-07
Identities = 74/322 (22%), Positives = 134/322 (41%), Gaps = 26/322 (8%)
Query: 200 RERDLNTAARIGQSLVKQNSVLMEENSKL---EALLGSAKEEILYLRHQVNLRDE--LLQ 254
R+R ++ Q +Q E + K E + ++E ++ + LR + Q
Sbjct: 1553 RDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQ 1612
Query: 255 LYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQL 314
L + D + ++E+ +E+E ++ +E + L+ + P+L QE H
Sbjct: 1613 LRQERDRKFREDEQLLQEREEQQLHRQERDRKFLE-----EEPQLRRQEREQQLRHDRDR 1667
Query: 315 EALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRL 374
+ +E+ L E E QLR + E+E+Q+ E +F + QQ+ R
Sbjct: 1668 KFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFRE 1727
Query: 375 ENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPGFQET 434
E RQ+ E + L+ Q+R R E E+L+ + +E Q++ QE + +E
Sbjct: 1728 EEQLRQETE-----QEQLRRQERYRKI-LEEEQLRPE---REEQQLRRQERDRKFREEEQ 1778
Query: 435 LAEEL-RTSLRRMISDPVYFMERNYEMPRGDTS--SLRYDFRYSEDREQVRGFEAEEGLM 491
L +E LR SD + E R + + D +Y + EQ++ E E+ L
Sbjct: 1779 LRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLR 1838
Query: 492 LAADIMRGEDFTPAEEFVPQEE 513
D + E+F QE+
Sbjct: 1839 QERD----RQYRAEEQFATQEK 1856
Score = 54.3 bits (129), Expect = 3e-07
Identities = 85/408 (20%), Positives = 154/408 (37%), Gaps = 78/408 (19%)
Query: 216 KQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEE------ 269
+Q +EE +L + + L Q+ ++ QL D D + +EE++
Sbjct: 1371 EQGRKFLEEEQRLRRQ--ERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQER 1428
Query: 270 -----EEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLL 324
EEE++ ++ E + E+ Q K +E LL + QL + + L
Sbjct: 1429 DRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFL 1488
Query: 325 EEENH-------------QLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLV 371
EEE +LR + + LE+E+Q+ + +F + QQ+ E
Sbjct: 1489 EEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRR-QERGQ 1547
Query: 372 LRLENYERQQQEVARL----QAQVLKLQQRCRMYGAETEKLQKQLASEK----------- 416
R ++ +R+ +E +L + Q L Q+R R + E +K+++Q K
Sbjct: 1548 QRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQ 1607
Query: 417 EIQMQLQEE--ETLPGFQETLAEELRTSLRRMISDPVY---------------------- 452
E Q QL++E ++ L E L R D +
Sbjct: 1608 EGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDR 1667
Query: 453 -FMERNYEMPRGDTSSLR---YDFRYSEDREQVRGFEAEEGLMLAADIMRGED----FTP 504
F E + G+ LR D ++ E+ +Q+R E E + +R ++ F
Sbjct: 1668 KFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFRE 1727
Query: 505 AEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGWEEVELELDEATR 552
E+ + E ++ ++EE +L E EE +L E R
Sbjct: 1728 EEQLRQETEQEQLRRQERYRKILEEEQLRPER----EEQQLRRQERDR 1771
Score = 52.4 bits (124), Expect = 1e-06
Identities = 73/296 (24%), Positives = 126/296 (42%), Gaps = 43/296 (14%)
Query: 261 EEDEDE--EEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQ 318
EE E++ +E + K EEEQ +E EE Q + + +E L HQ + +
Sbjct: 1323 EEREEKRRRQETDRKFREEEQLLQEREE--QPLRRQERDRKFREEELRHQEQGRKFLEEE 1380
Query: 319 EKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYE 378
++LR E E L+EE Q ++ EQ L + +F E QQ++ R E +
Sbjct: 1381 QRLRRQERERKFLKEE--QQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQ 1438
Query: 379 --RQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPGFQETLA 436
RQ++E L+ + Q+R R + E + LQ++ +E Q+ QE + ++ L
Sbjct: 1439 VRRQERERKFLEEEQQLRQERHRKFREEEQLLQER----EEQQLHRQERD-----RKFLE 1489
Query: 437 EELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAEEGLMLAADI 496
EE LRR ER+ + + S + ++ E+ +Q+ +
Sbjct: 1490 EE--QQLRR--------QERDRKFREQELRSQEPERKFLEEEQQLHRQQ----------- 1528
Query: 497 MRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGWEEVELELDEATR 552
R F E+ + ++E G ++ + EE +L E EE +L E R
Sbjct: 1529 -RQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQER----EEQQLSRQERDR 1579
Score = 52.4 bits (124), Expect = 1e-06
Identities = 59/194 (30%), Positives = 88/194 (45%), Gaps = 21/194 (10%)
Query: 236 KEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCD 295
+EE LR Q R L EE + +E E K EEEQ +E E++ Q
Sbjct: 1694 REEEQQLRRQERERKFL-------QEEQQLRRQELERKFREEEQLRQETEQE-QLRRQER 1745
Query: 296 APKLISQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQ 355
K++ +E L + QL + + EEE QLR+E +E+Q+ E +
Sbjct: 1746 YRKILEEEQLRPEREEQQLRRQERDRKFREEE--QLRQE-------REEQQLRSQESDRK 1796
Query: 356 FSEASQ--QMAELSEVLVLRLENYERQQQEVARLQAQVLKL-QQRCRMYGAETEKLQKQL 412
F E Q Q E ++ + + R ++E +L+ Q +L Q+R R Y AE E+ Q
Sbjct: 1797 FREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAE-EQFATQE 1855
Query: 413 ASEKEIQMQLQEEE 426
S +E Q QEEE
Sbjct: 1856 KSRREEQELWQEEE 1869
Score = 51.6 bits (122), Expect = 2e-06
Identities = 72/321 (22%), Positives = 129/321 (40%), Gaps = 46/321 (14%)
Query: 223 EENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEE----EEEEKEAEEE 278
E + E L +E++L + R EL + Y +EE + EEE EE EK +E
Sbjct: 1047 ERQYREEEELQQEEEQLLGEERETRRRQELERQYR-KEEELQQEEEQLLREEPEKRRRQE 1105
Query: 279 QEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQL 338
+E + EE+ E QE+ +LL EE + R + +
Sbjct: 1106 RERQCREEE---------------------------ELQQEEEQLLREEREKRRRQELER 1138
Query: 339 DTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRC 398
E+EE + + EQ + E LE R+++E+ + + Q+L+ +Q
Sbjct: 1139 QYREEEE---VQQEEEQLLREEPEKRRRQE-----LERQYREEEELQQEEEQLLREEQEK 1190
Query: 399 RMYGAETEKLQKQLASEKEIQMQLQEEETLPGFQETLAEELRTSLRRMISDPVYFMERNY 458
R E + +++ ++ + + ++E+ + E ++R + VY R
Sbjct: 1191 RRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVR---DNKVYCKGREN 1247
Query: 459 EMPRGDTSSLRYDFRYSEDREQVRGFEAEEGLMLAADIMRGED-FTPAEEFVPQEELGAA 517
E R S D + +D + + G + E + D P EE + +EE A
Sbjct: 1248 EQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEA 1307
Query: 518 KKVPAEEGVMEEAELVSEETE 538
K+ + EE +L+ EE E
Sbjct: 1308 KR--RDRKSQEEKQLLREERE 1326
Score = 50.1 bits (118), Expect = 6e-06
Identities = 94/414 (22%), Positives = 163/414 (39%), Gaps = 39/414 (9%)
Query: 198 LQRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYL--------RHQVNLR 249
L+RE+ L ++ + ++ E + E L +EE RH+ R
Sbjct: 413 LRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERR 472
Query: 250 DELLQLYSDSDEED-------EDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQ 302
+ QL D +EE E+EE E+++ E++ E+ E Q + + + Q
Sbjct: 473 KQ--QLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQ 530
Query: 303 EALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQ 362
Q + E +E+L EEE +E Q E EE+ L E+ +
Sbjct: 531 RLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRL 590
Query: 363 MAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKE---IQ 419
E E L RL +++EV RL+ Q + +QR + E E+ Q+ L SE++ Q
Sbjct: 591 KREQEERLEQRL-----KREEVERLE-QEERREQRLKREEPEEERRQQLLKSEEQEERRQ 644
Query: 420 MQLQEEETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDRE 479
QL+ E+ Q EE L + ++R +E R + + + +R
Sbjct: 645 QQLRREQQERREQRLKREEEEERLEQR-------LKREHEEERREQELAEEEQEQARERI 697
Query: 480 QVRGFEAEEGLMLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEE-GVMEEAELVSEETE 538
+ R + + L AD + + ++ P+++ G ++ EE E+EL +E E
Sbjct: 698 KSRIPKWQWQLESEADARQSKVYSR-----PRKQEGQRRRQEQEEKRRRRESELQWQEEE 752
Query: 539 GWEEVELELDEATRMNVVTSALEASGLGPSHLDMNYVLQQLANWQDAHYRRQLR 592
+ E ++ A E S G L L++ Q RQ R
Sbjct: 753 RAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQR 806
Score = 49.7 bits (117), Expect = 8e-06
Identities = 83/387 (21%), Positives = 149/387 (38%), Gaps = 65/387 (16%)
Query: 199 QRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSD 258
+R ++L R + L ++ L+ E + + E Y + R + Q Y D
Sbjct: 1161 RRRQELERQYREEEELQQEEEQLLREEQEKRR----QERERQYREEEELQRQKRKQRYRD 1216
Query: 259 SDEEDEDEEEEEEEKE------------AEEEQ---------EEEEAEEDLQCAHPCDAP 297
D+ + + + E EKE E EQ + ++++DLQ
Sbjct: 1217 EDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQE 1276
Query: 298 KLISQEALLHQH---HCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVE 354
+ QE Q H P+ E L+ + + + + +E QL E EE+ E
Sbjct: 1277 RDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDR 1336
Query: 355 QFSEASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLAS 414
+F E Q + E R E R+Q+ + + + L+ Q++ R + E ++L++Q
Sbjct: 1337 KFREEEQLLQE-------REEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERE 1389
Query: 415 EK----EIQMQLQEEETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRY 470
K E Q++ QE E ++LR R F E ++ R +
Sbjct: 1390 RKFLKEEQQLRCQERE----------QQLRQDRDRK------FREEEQQLSRQER----- 1428
Query: 471 DFRYSEDREQVRGFEAEEGLMLAADIMRGE---DFTPAEEFVPQEELGAAKKVPAEEGVM 527
D ++ E+ +QVR E E + +R E F E+ + + E + + +
Sbjct: 1429 DRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFL 1488
Query: 528 EEAELV--SEETEGWEEVELELDEATR 552
EE + + E + E EL E R
Sbjct: 1489 EEEQQLRRQERDRKFREQELRSQEPER 1515
Score = 49.3 bits (116), Expect = 1e-05
Identities = 70/330 (21%), Positives = 126/330 (38%), Gaps = 14/330 (4%)
Query: 223 EENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEE 282
+E E S K+E L R + +EL + + E +E EEE+ + + + EE
Sbjct: 144 QERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEE 203
Query: 283 EAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLR--------LLEEENHQLREE 334
+E+ + +E Q Q QE+ +L +E +L+EE
Sbjct: 204 FPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEE 263
Query: 335 --ASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQAQVL 392
Q + E+EEQ+ LE Q +Q E + + R + R+Q+E R Q +
Sbjct: 264 EPQRQRELQEEEEQLRKLE--RQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEER 321
Query: 393 KLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPGFQETLAEELRTSLRRMISDPVY 452
+ QQ R E + Q + E+ + QL+ E+ ++ L E R
Sbjct: 322 REQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQ 381
Query: 453 FMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAEEGLMLAADIMRGEDFTPAEEFVPQE 512
+ R ++ R R + + + E+ L + R ++ E+ QE
Sbjct: 382 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQE 441
Query: 513 ELGAAKKVPAEEGVMEEAELVSEETEGWEE 542
+++ E+ + EETE E+
Sbjct: 442 R--REQRLKREQEERRDWLKREEETERHEQ 469
Score = 48.5 bits (114), Expect = 2e-05
Identities = 64/248 (25%), Positives = 114/248 (45%), Gaps = 33/248 (13%)
Query: 198 LQRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEILY-LRHQVNLRDELLQLY 256
L+RE+ L R Q L ++ + E+ + E L +EE + +H+ R++ L+
Sbjct: 395 LRREQQL----RREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKRE 450
Query: 257 SDSDEEDEDEEEEEEEKEAEE--------EQEEEEAEEDLQCAHPCDAPKLISQEALLHQ 308
+ + D + EEE E+ +E +QEEE E L+ + + QE Q
Sbjct: 451 QE-ERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLE---EEERREQQERREQQ 506
Query: 309 HHCPQLEALQEKLRLLEEE---------NHQL-REEASQLDTLEDEEQMLILECVEQFSE 358
Q E +++L+ EEE QL RE+ + + L E+ LE +
Sbjct: 507 LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQR 566
Query: 359 ASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEI 418
++ E + L+ R E ER+QQ + R Q + +L+QR + E E+L+++ E+ +
Sbjct: 567 LKREQEERRDQLLKREE--ERRQQRLKREQEE--RLEQRLKR--EEVERLEQEERREQRL 620
Query: 419 QMQLQEEE 426
+ + EEE
Sbjct: 621 KREEPEEE 628
Score = 47.0 bits (110), Expect = 5e-05
Identities = 76/362 (20%), Positives = 144/362 (39%), Gaps = 20/362 (5%)
Query: 214 LVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEK 273
L K+ L EE + + L +E++ L Q R+ + E + ++E+
Sbjct: 253 LRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE 312
Query: 274 EAEEEQEE--EEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLEEENHQL 331
E E+QEE E+ E Q + QE Q + E + + +L E+ +
Sbjct: 313 ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEER 372
Query: 332 REEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQAQV 391
RE+ + + EQ L E + + ++ +L LR E R++Q++ R Q +
Sbjct: 373 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEE 432
Query: 392 LKLQQRCRMYGAETEKLQKQLASEKEIQMQ--LQEEETLPGFQETLAEELRTSLRRMISD 449
Q+ E E+ +++L E+E + +EEET QE ++L+ +
Sbjct: 433 RHEQKH------EQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRE 486
Query: 450 PVYFMERNYEMPRGDTSSLRYDFRYSEDREQ-VRGFEAEEGL---MLAADIMRGEDFTPA 505
+E + + + E REQ ++ E EE L + + +R E
Sbjct: 487 RWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERR 546
Query: 506 EEFVPQEELGAAKKVPAEEGVMEEAE------LVSEETEGWEEVELELDEATRMNVVTSA 559
E+ + +EE ++ E+ + E E L EE + ++ E +E +
Sbjct: 547 EQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREE 606
Query: 560 LE 561
+E
Sbjct: 607 VE 608
Score = 43.9 bits (102), Expect = 4e-04
Identities = 74/356 (20%), Positives = 137/356 (38%), Gaps = 61/356 (17%)
Query: 229 EALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEE----- 283
E+LL ++E R + RD L+ + +E+E E E EE+ E++E
Sbjct: 107 ESLLQDRRQEEDQRRFEP--RDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQR 164
Query: 284 ------------------------AEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQE 319
EE LQ + + +E L + E L+
Sbjct: 165 DRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRR------ELLEL 218
Query: 320 KLRLLEEENHQLREEASQLDTLEDE------EQMLILECVEQFSEASQQMAEL--SEVLV 371
+ + EE+ Q RE ++ E+E E +L E + E Q+ EL E +
Sbjct: 219 RRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQL 278
Query: 372 LRLENYE-RQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPG 430
+LE E R++++ Q Q L+ +Q+ R E + Q++ E++ + + QEE
Sbjct: 279 RKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQ 338
Query: 431 FQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAEEGL 490
+ E LRR + ER + R R E+ + + E+ L
Sbjct: 339 LRREQEERREQQLRREQEE-----ERREQQLR----------REQEEERREQQLRREQQL 383
Query: 491 MLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGWEEVELE 546
+ R + ++ +++L +++ E+ + E +L E+ E E + E
Sbjct: 384 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHE 439
Score = 42.4 bits (98), Expect = 0.001
Identities = 65/283 (22%), Positives = 118/283 (41%), Gaps = 38/283 (13%)
Query: 223 EENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEE 282
E + E L +E++L + R EL + Y E+EE ++EE++ E+ E+
Sbjct: 1107 ERQCREEEELQQEEEQLLREEREKRRRQELERQYR------EEEEVQQEEEQLLREEPEK 1160
Query: 283 EAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLE 342
++L+ + + +E LL + Q + QE+ R EE R++ Q E
Sbjct: 1161 RRRQELERQYREEEELQQEEEQLLREE---QEKRRQERERQYREEEELQRQKRKQRYRDE 1217
Query: 343 DEEQMLILECVEQFSEA------------SQQMAELSEVLV------LRLENYERQQQEV 384
D+ L + + A ++Q +L + + L++ +QQE
Sbjct: 1218 DQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQER 1277
Query: 385 ARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPGFQETLAEELRTSLR 444
R Q + + QQR R + E E+L+++ E + + + +EE ++ L EE R
Sbjct: 1278 DREQER-RRWQQRDRHF-PEEEQLEREEQKEAKRRDRKSQEE-----KQLLREEREEKRR 1330
Query: 445 RMISDPVYFMERNYEMPRGDTSSLRYD----FRYSEDREQVRG 483
R +D + E R + R + FR E R Q +G
Sbjct: 1331 RQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQG 1373
Score = 40.4 bits (93), Expect = 0.005
Identities = 52/235 (22%), Positives = 92/235 (39%), Gaps = 17/235 (7%)
Query: 200 RERDLNTAARIGQSLVKQNSVLMEENSKL---EALLGSAKEEILYLRHQVNLRDELLQLY 256
R+R ++ Q +Q E + K E L + E +L+ + LR + L+
Sbjct: 1665 RDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERK 1724
Query: 257 SDSDEEDEDEEEEEE-------EKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQH 309
+E+ E E+E+ K EEEQ E EE D K +E L +
Sbjct: 1725 FREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDR-KFREEEQLRQER 1783
Query: 310 HCPQLEALQEKLRLLEEENHQLREEASQLDTLED------EEQMLILECVEQFSEASQQM 363
QL + + + EEE + E QL + EE+ L LE EQ +
Sbjct: 1784 EEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDR 1843
Query: 364 AELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEI 418
+E E R++QE+ + + Q + ++ ++ + QK+ +++
Sbjct: 1844 QYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQV 1898
Score = 40.0 bits (92), Expect = 0.006
Identities = 32/130 (24%), Positives = 59/130 (45%), Gaps = 9/130 (6%)
Query: 261 EEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEK 320
EE + +E + K EEEQ +E EE D +E L QLE +++
Sbjct: 1784 EEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQL-------QLEEQEQR 1836
Query: 321 LRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQ 380
LR + ++ E+ + + EEQ L E E+ ++ +L E + R + E++
Sbjct: 1837 LRQERDRQYRAEEQFATQEKSRREEQELWQE--EEQKRRQERERKLREEHIRRQQKEEQR 1894
Query: 381 QQEVARLQAQ 390
++V +++Q
Sbjct: 1895 HRQVGEIKSQ 1904
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 62.4 bits (150), Expect = 1e-09
Identities = 85/358 (23%), Positives = 161/358 (44%), Gaps = 45/358 (12%)
Query: 212 QSLVKQNSVLMEENSK---LEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDE-DEE 267
+ + +Q ++ E+ K LE ++ +E+I L +++ ++++ + EE++ E+
Sbjct: 349 EKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 408
Query: 268 EEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLEEE 327
E+ +E+EA+ ++EE+ E + K+ QE +H+ QEK+R EEE
Sbjct: 409 EKRQEQEAKMWRQEEKIREQEEKIRE-QEKKMWRQEEKIHE---------QEKIR--EEE 456
Query: 328 NHQLREEA-SQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEVAR 386
Q +EE Q + + ++E+ I E+ E Q+ E V R E Q+E R
Sbjct: 457 KRQEQEEMWRQEEKIREQEE--IWRQKEKMHE--QEKIRKQEEKVWRQEEKMHDQEEKIR 512
Query: 387 LQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPGFQETLAEELRTSLRRM 446
Q + K+ ++ + EK+++Q +E + +QE+E G QE +E
Sbjct: 513 EQEE--KMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEK----- 565
Query: 447 ISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAEEGLMLAADIMRGEDFTPAE 506
M R E R +R ++E+ + +E EE + ++M+ ++ E
Sbjct: 566 -------MRRQEEKIREQEEKIREQKEKIREQEE-KIWEQEEKIREQEEMMQEQE----E 613
Query: 507 EFVPQEELGAAKKVPAEEGVMEEAELVSEETEGWEEVELEL-DEATRMNVVTSALEAS 563
+ QEE K EE + E+ E + + E E E+ L + +M LEA+
Sbjct: 614 KMWEQEE----KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 667
Score = 55.8 bits (133), Expect = 1e-07
Identities = 73/372 (19%), Positives = 163/372 (43%), Gaps = 34/372 (9%)
Query: 202 RDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDE 261
++L + + Q+ V++N + N + E + +E+I ++ ++E ++ +
Sbjct: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR 331
Query: 262 EDEDEEEEEEEKEAEEEQ----------EEEEAEEDLQCAHPCDAPKLISQEALLHQHH- 310
E E++ +EE E+E+ E+EE L+ K+ E +H+
Sbjct: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEK 391
Query: 311 -CPQLEALQEKLRLLEEENHQLREEA--SQLDTLEDEEQMLILECVEQFSEASQQMAELS 367
Q E QE+ ++ E+E Q +E Q + + ++E+ + EQ + +Q ++
Sbjct: 392 IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI----REQEKKMWRQEEKIH 447
Query: 368 EVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEET 427
E +R E ++Q+E+ R + ++ + ++ R + EK+ +Q K+ + ++EE
Sbjct: 448 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWR----QKEKMHEQEKIRKQEEKVWRQEEK 503
Query: 428 LPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAE 487
+ +E + E+ R+ + E R +R +++E+ G E E
Sbjct: 504 MHDQEEKIREQEEKMWRQEEK-----IREQEEKIREQEEKIREQEEMMQEQEEKMG-EQE 557
Query: 488 EGLMLAADIMRGEDFTPAEEFVPQEELGAAKKV-----PAEEGVMEEAELVSEETEG-WE 541
E + + R E+ +E +E+ ++ EE + E+ E++ E+ E WE
Sbjct: 558 EKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWE 617
Query: 542 EVELELDEATRM 553
+ E ++ +M
Sbjct: 618 QEEKMCEQEEKM 629
Score = 52.8 bits (125), Expect = 9e-07
Identities = 86/391 (21%), Positives = 165/391 (42%), Gaps = 44/391 (11%)
Query: 169 ITQEDVKVMLYLLEELLPPVW--ESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENS 226
IT E++K L+E L V +S V + +R L A L+ L E
Sbjct: 214 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERA-----KLLLPQQQLQAEAD 268
Query: 227 KLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEE 286
L L S ++ + L + L Q + E++ +E EEK E+E++ E EE
Sbjct: 269 HLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE 328
Query: 287 DLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQ 346
++ K+ QE ++ + +EK+R EE + E+ +L+ + E++
Sbjct: 329 KIR----EQEEKMRRQEEMMWEK--------EEKMRRQEEMMWEKEEKMRRLEEMMWEKE 376
Query: 347 MLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETE 406
I E E+ E ++ E ++QE +++ Q + +Q +M+ E E
Sbjct: 377 EKIRELEEKMHEQE------------KIREQEEKRQEEEKIREQEKRQEQEAKMWRQE-E 423
Query: 407 KLQKQLASEKEIQMQL-QEEETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDT 465
K+++Q +E + ++ ++EE + ++ EE R M E+ + +
Sbjct: 424 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 483
Query: 466 SSLRYDFRYSED---REQVRGFEAEEGLMLAADIMRGEDFTPAEEFVPQEELGAAKKVPA 522
+ R E+ R++ + + EE + + M ++ E+ QEE K
Sbjct: 484 MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQE----EKIREQEE----KIREQ 535
Query: 523 EEGVMEEAELVSEETEGWEEVELELDEATRM 553
EE + E+ E++ E+ E E E ++ E +M
Sbjct: 536 EEKIREQEEMMQEQEEKMGEQEEKMQEQEKM 566
Score = 45.1 bits (105), Expect = 2e-04
Identities = 47/239 (19%), Positives = 108/239 (45%), Gaps = 18/239 (7%)
Query: 216 KQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEE----- 270
+Q + E+ E +EE+ ++ ++E+ + E+++ ++EE
Sbjct: 441 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQ 500
Query: 271 EEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLEEENHQ 330
EEK ++E++ E EE + K+ QE + + Q E ++E+ +++E+ +
Sbjct: 501 EEKMHDQEEKIREQEEKMWRQEE----KIREQEEKIRE----QEEKIREQEEMMQEQEEK 552
Query: 331 LREEASQLDTLED--EEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQ 388
+ E+ ++ E ++ I E E+ E +++ E E + E E+ +++ +Q
Sbjct: 553 MGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKI---WEQEEKIREQEEMMQ 609
Query: 389 AQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPGFQETLAEELRTSLRRMI 447
Q K+ ++ + EK+Q+Q + + ++ E+E QE +E + L I
Sbjct: 610 EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 62.4 bits (150), Expect = 1e-09
Identities = 50/187 (26%), Positives = 95/187 (50%), Gaps = 8/187 (4%)
Query: 243 RHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQ 302
R L E Q SD ++E+E+EEEEE++ + E +E ++E D + + D I+
Sbjct: 581 RENNELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLAN-ITC 639
Query: 303 EALLHQHHCPQLEALQEKLRLLE---EENHQLREEASQLDTLEDEEQMLILECVEQFSEA 359
E + Q +LE Q++L+ L+ EE + + + LE ++ + L VE +SE
Sbjct: 640 EIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEE 699
Query: 360 SQQMAELSEVLVLRLENYERQQQEVARLQ-AQVLKLQQRCRMYGAETEKLQKQLASEKEI 418
+ L+ N E Q+ + A+ + A++LK Q + Y + +KLQ+ + K+
Sbjct: 700 KAKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQ---YEKQLKKLQQDVMEMKKT 756
Query: 419 QMQLQEE 425
+++L ++
Sbjct: 757 KVRLMKQ 763
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 61.6 bits (148), Expect = 2e-09
Identities = 85/331 (25%), Positives = 142/331 (42%), Gaps = 33/331 (9%)
Query: 197 VLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLY 256
V Q + + N + +S+ +Q +E N L L +E + ++ ++E L+
Sbjct: 159 VEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQ 218
Query: 257 SDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEA 316
+ E E+ E+EE+ E+E+ E EE L+ H +L QE L C Q E
Sbjct: 219 EERLCEQEERLREQEERLREQEERLCEQEERLR-EH---EERLCEQEERL----CEQEER 270
Query: 317 LQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLEN 376
L+E+ L E+ +L E+ +L E++ + E E+ E +++ E E RL
Sbjct: 271 LREQEERLHEQEERLCEQEERL----REQEERLCEQEERLREQEERLCEQEE----RLRE 322
Query: 377 YERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPGFQETLA 436
E + E +L Q L+ E EKL +Q ++E + L+ E L +E L
Sbjct: 323 QEERLCEQEKLPGQERLLE--------EVEKLLEQERRQEEQERLLERERLLEEVEELLE 374
Query: 437 EE-LRTSLRRM-ISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEA-----EEG 489
+E LR R+ + + +ER E+ R L ++ Y + E GFE +
Sbjct: 375 QERLRQQDERLWQQETLQELERLRELER--MLELGWEALYEQRAEPRSGFEELNNENKST 432
Query: 490 LMLAADIMRGEDFTPAEEFVPQEELGAAKKV 520
L L + + AEE E AA+ V
Sbjct: 433 LQLEQQVKELKKSGGAEEPRGSESAAAARPV 463
Score = 55.1 bits (131), Expect = 2e-07
Identities = 92/386 (23%), Positives = 159/386 (41%), Gaps = 81/386 (20%)
Query: 199 QRERDLNTAARIGQSLVKQNSVLMEE--------NSKLEALLGSA---KEEILYLRHQVN 247
+++ +++ ++G+SL K + E SK+E L ++E+ + Q+
Sbjct: 122 EKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQ 181
Query: 248 LRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLH 307
E Q+ S + E+ E+EE+ E+E+ E EE L
Sbjct: 182 AEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERL------------------- 222
Query: 308 QHHCPQLEALQEKLRLLEEENHQLREEASQLDTLED---EEQMLILECVEQFSEASQQMA 364
C Q +E+LR E+ +LRE+ +L E+ E + + E E+ E +++
Sbjct: 223 ---CEQ----EERLR---EQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLR 272
Query: 365 ELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQE 424
E E L E ER ++ RL+ Q +L ++ + E+L +Q +E + +L E
Sbjct: 273 EQEERL---HEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCE 329
Query: 425 EETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGF 484
+E LPG QE L EE+ L + ER E EQ R
Sbjct: 330 QEKLPG-QERLLEEVEKLLEQ---------ERRQE-------------------EQERLL 360
Query: 485 EAEEGLMLAADIMRGEDFTPAEEFV-PQEELGAAKKVPAEEGVME---EA--ELVSEETE 538
E E L +++ E +E + QE L +++ E ++E EA E +E
Sbjct: 361 ERERLLEEVEELLEQERLRQQDERLWQQETLQELERLRELERMLELGWEALYEQRAEPRS 420
Query: 539 GWEEVELELDEATRMNVVTSALEASG 564
G+EE+ E ++ L+ SG
Sbjct: 421 GFEELNNENKSTLQLEQQVKELKKSG 446
Score = 54.3 bits (129), Expect = 3e-07
Identities = 68/291 (23%), Positives = 122/291 (41%), Gaps = 35/291 (12%)
Query: 312 PQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLV 371
P+ A K+ L++E + LR+E LE V + +A + ++ +L
Sbjct: 150 PEPPAGPSKVEQLQDETNHLRKE---------------LESVGRQLQAEVENNQMLSLLN 194
Query: 372 LRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPGF 431
R E R+Q+E RL+ Q +L+++ + E+L++Q +E + +L E+E
Sbjct: 195 RRQEERLREQEE--RLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQE----- 247
Query: 432 QETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAEEGLM 491
E LR R+ E+ + + + R E E++R E EE L
Sbjct: 248 -----ERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLR--EQEERLC 300
Query: 492 LAADIMRGEDFTPAEEFV----PQEELGAAKKVPAEEGVMEEAELVSEETEGWEEVELEL 547
+ +R ++ E+ +E L +K+P +E ++EE E + E+ EE E L
Sbjct: 301 EQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLL 360
Query: 548 DEATRMNVVTSALEASGL--GPSHLDMNYVLQQLANWQDAHYRRQLRWKML 596
+ + V LE L L LQ+L ++ +L W+ L
Sbjct: 361 ERERLLEEVEELLEQERLRQQDERLWQQETLQELERLRELERMLELGWEAL 411
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 61.6 bits (148), Expect = 2e-09
Identities = 49/274 (17%), Positives = 126/274 (45%), Gaps = 10/274 (3%)
Query: 212 QSLVKQNSVLMEENSKL---EALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEE 268
+ + +Q + E+ K+ E ++ +E++ + ++E ++ + E E E
Sbjct: 302 EKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 361
Query: 269 EEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLEEEN 328
+EE+++ EE+ E+E ++ + K+ QE + + Q E +QE+ + E+
Sbjct: 362 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE----QEEMMQEQEEKMGEQE 417
Query: 329 HQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQ 388
++ E+ ++ E++ + + EQ + +Q ++ E + E E+ ++ ++
Sbjct: 418 EKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMC 477
Query: 389 AQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPGFQETLAEELRTSLRRMIS 448
Q K+Q++ + EK+++Q +E + +++E+E + QE E++ +M
Sbjct: 478 EQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQE---EKMWEQEEKMCE 534
Query: 449 DPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVR 482
E+ +M R + + R + E+++
Sbjct: 535 QEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQ 568
Score = 60.5 bits (145), Expect = 5e-09
Identities = 87/385 (22%), Positives = 166/385 (43%), Gaps = 32/385 (8%)
Query: 169 ITQEDVKVMLYLLEELLPPVW--ESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENS 226
IT E++K L+E L V +S V + +R L A L+ L E
Sbjct: 202 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERA-----KLLLPQQQLQAEAD 256
Query: 227 KLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEE 286
L L S ++ + L + L Q + E++ +E EEK E+E++ E EE
Sbjct: 257 HLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEE 316
Query: 287 DLQCAHPC---DAPKLISQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLED 343
++ K+ QE ++ + +EK+R LEE+ H+ + Q + ++
Sbjct: 317 KMRRQEEMMWEKEEKMRRQEEMMWEK--------EEKIRELEEKMHEQEKIREQEEKRQE 368
Query: 344 EEQMLILE-CVEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYG 402
EE++ E EQ ++ +Q ++ E E E Q++ ++ Q K+ ++
Sbjct: 369 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQ 428
Query: 403 AETEKLQKQLASEKEIQMQLQEEETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPR 462
+ EK+++Q +E + +++E+E QE + +E +M E+ +M
Sbjct: 429 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQE---EKMGEQEGKMCEQEAKMQE 485
Query: 463 GDTSSLRYDFRYSEDREQVRGFEAEEGLMLAADIMRGEDFTPAEEFVPQEELGAAKKVPA 522
+ R + + E +++R E EE + ++M+ ++ E+ QEE K
Sbjct: 486 QEEKMRRQEEKIREQEKKIR--EQEEKIREQEEMMQEQE----EKMWEQEE----KMCEQ 535
Query: 523 EEGVMEEAELVSEETEGWEEVELEL 547
EE + E+ E + + E E E+ L
Sbjct: 536 EEKMQEQEEKMRRQEEKMREQEVRL 560
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 61.6 bits (148), Expect = 2e-09
Identities = 87/419 (20%), Positives = 181/419 (43%), Gaps = 75/419 (17%)
Query: 165 PVKKITQEDVKVMLYLLEELLPPVWESVTYGMVLQRERDLNTAARIGQSLVKQNSVLME- 223
P+ ++T+++ + L +E L V E T + E +L R Q L+++ ++L E
Sbjct: 843 PLLQVTRQEEE--LQAKDEELLKVKEKQT-----KVEGELEEMERKHQQLLEEKNILAEQ 895
Query: 224 ---------ENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKE 274
E ++ A L + K+E+ + H + R E + +E ++ + E+++ +
Sbjct: 896 LQAETELFAEAEEMRARLAAKKQELEEILHDLESRVE------EEEERNQILQNEKKKMQ 949
Query: 275 AEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLEEENHQLREE 334
A + EE+ +E+ K+ ++ +++ ++E++ LLE++N + +E
Sbjct: 950 AHIQDLEEQLDEEEGARQKLQLEKVTAE---------AKIKKMEEEILLLEDQNSKFIKE 1000
Query: 335 ASQLDTLEDEEQMLILECVEQFSEASQQMAELSEV----------LVLRLENYERQQQEV 384
+ED I EC Q +E ++ L+++ L RL+ E+ +QE+
Sbjct: 1001 KK---LMEDR----IAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQEL 1053
Query: 385 ----ARLQAQVLKLQQRCRMYGAETEKLQKQLA-SEKEIQMQLQEEETLPGFQETLAEEL 439
+L + LQ + A+ ++L+ QLA E+E+Q L G ETL +
Sbjct: 1054 EKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALAR-----GDDETLHKNN 1108
Query: 440 RTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAEEGLMLAADIMRG 499
+ R + + ++ ++E + + R + + E E+ L
Sbjct: 1109 ALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTL--------- 1159
Query: 500 EDFTPAEEFV---PQEELGAAKKVPAEEGVMEEAELV---SEETEGWEEVELELDEATR 552
D T A++ + ++E+ KK EE EA++ EE+ +L++A R
Sbjct: 1160 -DTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKR 1217
Score = 47.4 bits (111), Expect = 4e-05
Identities = 52/270 (19%), Positives = 111/270 (41%), Gaps = 28/270 (10%)
Query: 201 ERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEILY-LRHQVNLRDELLQLYSDS 259
+ +L+ + + + K+ ++ + LE+ L +E + R ++NL + QL +
Sbjct: 1286 QNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEK 1345
Query: 260 DEEDEDEEEEEEEKEAEEEQ----------EEEEAEEDLQCAHPCD--APKLISQEALLH 307
+ E +EEEEE ++ E+Q +++ ++DL + KL+ L
Sbjct: 1346 NSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALS 1405
Query: 308 QHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELS 367
Q +LE LE+ ++L++E L D ++ + ++ + Q +AE
Sbjct: 1406 Q----RLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEK 1461
Query: 368 EVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQ-----------LASEK 416
+ E +R + E + + L L + E+ ++Q ++S+
Sbjct: 1462 SISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKD 1521
Query: 417 EIQMQLQEEETLPGFQETLAEELRTSLRRM 446
++ + E E E EE+RT L +
Sbjct: 1522 DVGKNVHELEKSKRALEQQVEEMRTQLEEL 1551
Score = 41.6 bits (96), Expect = 0.002
Identities = 54/260 (20%), Positives = 112/260 (43%), Gaps = 19/260 (7%)
Query: 201 ERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYL----RHQVNLRDELLQLY 256
+R+L A + Q+ ++ LEA + +EE+ RH RDEL
Sbjct: 1658 QRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEI 1717
Query: 257 SDSDEEDE---DEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQ 313
++S DE+ E + A+ E+E EE + +++ + K Q L+ +
Sbjct: 1718 TNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLND-RFRKTTLQVDTLNAELAAE 1776
Query: 314 LEALQEK---LRLLEEENHQLREEASQLDTLEDEEQMLILECVE-QFSEASQQMAELSEV 369
A Q+ + LE +N +L+ + +L+ + + +E + + +Q+ + ++
Sbjct: 1777 RSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKE 1836
Query: 370 LVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLP 429
+ R ++++ + QV ++ Y E+++K A K+++ QL+E E
Sbjct: 1837 RAAANKLVRRTEKKLKEIFMQVEDERRHADQY---KEQMEKANARMKQLKRQLEEAEE-- 1891
Query: 430 GFQETLAEELRTSLRRMISD 449
+ T A R L+R + D
Sbjct: 1892 --EATRANASRRKLQRELDD 1909
Score = 41.2 bits (95), Expect = 0.003
Identities = 49/224 (21%), Positives = 100/224 (44%), Gaps = 21/224 (9%)
Query: 226 SKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAE 285
+K++ LL ++E ++ +DE L + + E E EE E K + +E+
Sbjct: 839 TKVKPLLQVTRQE-----EELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILA 893
Query: 286 EDLQCAHP--CDAPKLISQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDT-LE 342
E LQ +A ++ ++ A Q L L+ ++ EE N L+ E ++ ++
Sbjct: 894 EQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQ 953
Query: 343 DEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYG 402
D E+ L E E ++Q +L +V ++ ++E+ L+ Q K + ++
Sbjct: 954 DLEEQLDEE------EGARQKLQLEKVTAEA--KIKKMEEEILLLEDQNSKFIKEKKLME 1005
Query: 403 AETEKLQKQLASEKE-----IQMQLQEEETLPGFQETLAEELRT 441
+ QLA E+E +++ ++E + +E L +E +T
Sbjct: 1006 DRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKT 1049
Score = 38.5 bits (88), Expect = 0.019
Identities = 42/193 (21%), Positives = 85/193 (44%), Gaps = 28/193 (14%)
Query: 244 HQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQE 303
H+ ++D + Q ++ + EE ++ E+ + +A E+ ++ E D + C+ K++ Q
Sbjct: 1190 HEAQIQD-MRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNK-ELACEV-KVLQQV 1246
Query: 304 ALLHQHHCPQLEALQEKLRL-----------LEEENHQLREEASQLDTLEDEEQMLILEC 352
+H +L+A ++L L E+ +L+ E + TL +E + ++
Sbjct: 1247 KAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKF 1306
Query: 353 VEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQL 412
+ + Q+ + E+L QE R Q L L R R E LQ+Q
Sbjct: 1307 AKDAASLESQLQDTQELL-----------QEETR---QKLNLSSRIRQLEEEKNSLQEQQ 1352
Query: 413 ASEKEIQMQLQEE 425
E+E + L+++
Sbjct: 1353 EEEEEARKNLEKQ 1365
Score = 38.1 bits (87), Expect = 0.024
Identities = 79/398 (19%), Positives = 148/398 (37%), Gaps = 70/398 (17%)
Query: 214 LVKQNSVLMEENSKLEALLGSAKEEI-----LYLRHQVNLRDELLQLYSDSDEEDEDEEE 268
L K L ++ ++ L ++E+ LR +VN++ Q D DE EE
Sbjct: 1530 LEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEE 1589
Query: 269 E-----EEEKEAEEEQEEEEAEEDLQCAHP-------CDAPKLISQEALLHQHHCPQLEA 316
+ ++ +E E E E+E + L A D I QL
Sbjct: 1590 KKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRK 1649
Query: 317 LQEKLRLLEEENHQLREEASQL--DTLEDEEQMLILEC-VEQFSE-----------ASQQ 362
LQ +++ + E + R ++ + E E+++ LE + Q E A Q+
Sbjct: 1650 LQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQE 1709
Query: 363 MAELSEVLVLRLENYERQQQEVARLQAQVLKLQQ--------------RCRMYGAETEKL 408
EL++ + E RL+A++ +L++ R R + + L
Sbjct: 1710 RDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTL 1769
Query: 409 QKQLASEKEI---------QMQLQEEETLPGFQETLAEELRTSLRRMIS---DPVYFMER 456
+LA+E+ Q++ Q +E QE L +++ + IS + +E
Sbjct: 1770 NAELAAERSAAQKSDNARQQLERQNKELKAKLQE-LEGAVKSKFKATISALEAKIGQLEE 1828
Query: 457 NYEMPRGDTSSLRYDFRYSEDREQVRGFEAEEGLMLAADIMRGEDFTPAEEFVPQEELGA 516
E + ++ R +E + +E M D R A+++ Q E
Sbjct: 1829 QLEQEAKERAAANKLVRRTEKK-------LKEIFMQVEDERR-----HADQYKEQMEKAN 1876
Query: 517 AKKVPAEEGVMEEAELVSEETEGWEEVELELDEATRMN 554
A+ + + E E + +++ ELD+AT N
Sbjct: 1877 ARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEAN 1914
Score = 37.4 bits (85), Expect = 0.041
Identities = 72/334 (21%), Positives = 132/334 (39%), Gaps = 36/334 (10%)
Query: 248 LRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLH 307
L+ EL L D D + + E++++ ++ EE + A D + ++E
Sbjct: 1425 LQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREK--E 1482
Query: 308 QHHCPQLEALQEKLRLLEE---ENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMA 364
AL+E L EE +N QLR + L + +D+ + E +E+ A +Q
Sbjct: 1483 TKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHE-LEKSKRALEQQV 1541
Query: 365 ELSEVLVLRLENYERQQQEVARL------QAQVLKLQQRCRMYGAETEKLQKQLASE-KE 417
E + LE+ E Q E A+L QA + ++ + + E+ ++ L + +E
Sbjct: 1542 EEMRTQLEELED-ELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRE 1600
Query: 418 IQMQLQEEETLPGFQETLAEELRTSLRRM---------ISDPVYFMERNYEMPRGDTSSL 468
++ +L++E +++ L+ + D V R + D
Sbjct: 1601 LEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRE 1660
Query: 469 RYDFRYSEDREQVRGFEAEEGL-MLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVM 527
+ R S D + E+E+ L L A+I++ QEEL ++++
Sbjct: 1661 LEEARASRDEIFAQSKESEKKLKSLEAEILQ-----------LQEELASSERA-RRHAEQ 1708
Query: 528 EEAELVSEETEGWEEVELELDEATRMNVVTSALE 561
E EL E T LDE R+ + LE
Sbjct: 1709 ERDELADEITNSASGKSALLDEKRRLEARIAQLE 1742
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 60.8 bits (146), Expect = 3e-09
Identities = 77/340 (22%), Positives = 154/340 (45%), Gaps = 26/340 (7%)
Query: 216 KQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEA 275
+Q + + +L +E+ LR Q LR++ Q+ ++ E EE+ E++E
Sbjct: 273 EQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEK 332
Query: 276 EEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLEEENHQLREEA 335
QEE E++ Q K+ QE + + E+LR EE + +
Sbjct: 333 MWRQEERLWEQEKQMRE--QEQKMRDQEERMWEQ--------DERLREKEERMREQEKMW 382
Query: 336 SQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQ 395
Q + +++EE+ I E ++ E + M E E + + EN +QE Q Q L +
Sbjct: 383 EQEEKMQEEER--IREREKKMREEEETMREQEEKMQKQEEN--MWEQEEKEWQQQRLP-E 437
Query: 396 QRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPGFQETL--AEELRTSLRRMISDPVYF 453
Q+ +++ E EK+Q+Q E + +++++E + G ++ + E++R +M
Sbjct: 438 QKEKLW--EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKM 495
Query: 454 MERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAEEGLMLAADIMRGEDFTPAEE---FVP 510
++ +M + D R E E++R ++ + + MR E T +E +
Sbjct: 496 RDQEQKMWDQEERMWEQDERLREKEERMR---EQKKMWQQEEKMREEKKTQEQEKKTWDQ 552
Query: 511 QEELGAAKKVPAEEGVM-EEAELVSEETEGWEEVELELDE 549
+E++ +++ E M EE E++ E+ E +E E ++ E
Sbjct: 553 EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMRE 592
Score = 53.1 bits (126), Expect = 7e-07
Identities = 56/246 (22%), Positives = 121/246 (49%), Gaps = 15/246 (6%)
Query: 199 QRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGS-AKEEILYLRHQVNLRDELLQLYS 257
+R R+ R + + +Q + EE E + +EE + ++ R++ ++
Sbjct: 514 ERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE 573
Query: 258 DSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEAL 317
+ E E++ +E+EEK E+E++ E EE +Q K+ QE + + + + +
Sbjct: 574 EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQ----EQEEKMWEQEEKMWEQE--EEDKM 627
Query: 318 QEKLRLLEEENHQLREEASQLDTLED---EEQMLILECVEQFSEASQQMAELSEVLVLRL 374
QE+ ++ E+ +++E+ ++ E+ E++ + E E+ ++M E E + +
Sbjct: 628 QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQ- 686
Query: 375 ENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEE---ETLPGF 431
E R+Q+E R Q + + Q+ +M+G E + ++ EKE +++ Q+E E LP
Sbjct: 687 EEKMREQEEKMRGQEEKMWGQEE-KMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEH 745
Query: 432 QETLAE 437
+E +E
Sbjct: 746 EERCSE 751
Score = 49.3 bits (116), Expect = 1e-05
Identities = 51/231 (22%), Positives = 107/231 (46%), Gaps = 21/231 (9%)
Query: 242 LRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLIS 301
LR + E +++ ++ E+++ +E+EK+ +++E+ EE ++ + K +
Sbjct: 516 LREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMR-----EREKKMR 570
Query: 302 QEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLD--TLEDEEQMLILECVEQFSEA 359
+E + + +++ +EK+R EE+ + E+ + + E EE+M E ++ E
Sbjct: 571 EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQ 630
Query: 360 SQQMAELSEVL------VLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLA 413
+ M E E + + E R+Q+E R Q + ++ Q+ E + Q++
Sbjct: 631 EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKM 690
Query: 414 SEKEIQMQLQE------EETLPGFQETL--AEELRTSLRRMISDPVYFMER 456
E+E +M+ QE EE + G +E + EE+R R+ ER
Sbjct: 691 REQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQER 741
Score = 41.6 bits (96), Expect = 0.002
Identities = 59/255 (23%), Positives = 105/255 (41%), Gaps = 42/255 (16%)
Query: 317 LQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLEN 376
LQEKLRL E E +++ +L + + L+ + Q L E + + E
Sbjct: 192 LQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQV---------QTNTLQEEMWRQEEE 242
Query: 377 YERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQE------EETLPG 430
Q++++ + + ++ + ++R R Q+ E+E +M+ QE E+ L
Sbjct: 243 LREQEKKIRKQEEKMWRQEERLRE--------QEGKMREQEEKMRRQEKRLREQEKELRE 294
Query: 431 FQETLAEE--LRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRG----- 483
++ L E+ LR +M E+ +M + R + R E +Q+R
Sbjct: 295 QEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKM 354
Query: 484 -------FEAEEGLMLAADIMRGEDFTPAEEFVPQEE---LGAAKKVPAEEGVMEEAE-- 531
+E +E L + MR ++ +E QEE KK+ EE M E E
Sbjct: 355 RDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEK 414
Query: 532 LVSEETEGWEEVELE 546
+ +E WE+ E E
Sbjct: 415 MQKQEENMWEQEEKE 429
Score = 30.0 bits (66), Expect = 6.6
Identities = 11/39 (28%), Positives = 23/39 (58%)
Query: 262 EDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLI 300
++E E+EE ++ +E+ +E E + +C+ PC P +
Sbjct: 721 QEEMREKEERIRDQKEKMQERLPEHEERCSEPCLPPSKV 759
>gi|126723390 ankyrin repeat domain 24 [Homo sapiens]
Length = 1146
Score = 60.8 bits (146), Expect = 3e-09
Identities = 100/425 (23%), Positives = 162/425 (38%), Gaps = 53/425 (12%)
Query: 203 DLNTAARIGQSLVKQNSVLMEENSKLEALLG---SAKEEILYLRHQVN------------ 247
+L T R + ++Q E ++LEA LG +A+ E LR +V
Sbjct: 724 ELETRIRGLEEALRQRE--REAAAELEAALGKCEAAEAEAGRLRERVREAEGSGASGGGG 781
Query: 248 -----LRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEE--AEEDLQCAHPCDAPKLI 300
LR L Q D + D E E +E AEE+ A A
Sbjct: 782 GDTTQLRAALEQAREDLRDRDSRLRELEAASACLDEARASRLLAEEE---ARGLRAELAQ 838
Query: 301 SQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEAS 360
+EA L Q +LE L+E+L Q R A++L D + + E EA
Sbjct: 839 REEARLEQSR--ELEVLREQLATARATGEQQRTAAAELGRARDAAEARVAELPAACEEAR 896
Query: 361 QQMAELSEVL------VLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLAS 414
Q +AEL E V+ + R Q+E L+ + L+Q G E +L+ +L
Sbjct: 897 QGLAELREASEALRQSVVPASEHRRLQEEALELRGRAASLEQEVVATGKEAARLRAELER 956
Query: 415 EKEIQMQLQEEETLPGFQETLAEELRTSLRRM------ISDPVYFMERNYEMPRGDTSSL 468
E+ + L E E + G + +L L + S V+ ++R + + +
Sbjct: 957 ERVCSVALSEHERIVGTLQANVAQLEGQLEELGRRHEKTSAEVFQVQREALFMKSERHAA 1016
Query: 469 RYDFRYSEDREQVRGFEAEEGLMLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVME 528
+E +Q+RG E A E A+E + + + +E + E
Sbjct: 1017 EAQLATAE--QQLRGLRTEAERARQAQSRAQEALDKAKEKDKKITELSKEVFNLKEALKE 1074
Query: 529 E-AELVSEETEGW----EEVELELDEATRMNVVTSALEASGL-----GPSHLDMNYVLQQ 578
+ A L + E E ++++ +L EA R + AL S L G D+ +L Q
Sbjct: 1075 QPAALATPEVEALRDQVKDLQQQLQEAARDHSSVVALYRSHLLYAIQGQMDEDVQRILSQ 1134
Query: 579 LANWQ 583
+ Q
Sbjct: 1135 ILQMQ 1139
>gi|44890059 involucrin [Homo sapiens]
Length = 585
Score = 60.5 bits (145), Expect = 5e-09
Identities = 91/386 (23%), Positives = 164/386 (42%), Gaps = 44/386 (11%)
Query: 199 QRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYL-----RHQVNLRDELL 253
QR++ LN + L+ Q L +E K + LG KE++L L H +L +
Sbjct: 114 QRDQQLNKQLEEEKKLLDQQ--LDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEG 171
Query: 254 QLYSDSDEEDEDEEEEEEEKEAE-EEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCP 312
QL +E + E E++E + E EQ+E + E Q + P+ + L +
Sbjct: 172 QLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEG 231
Query: 313 QLEALQE---KLRLLEEENHQL---REEASQLDTLE--------DEEQMLILECVEQ--- 355
QLE Q+ +L L E++ QL ++ QL LE EEQM L+ +EQ
Sbjct: 232 QLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEG 291
Query: 356 ---FSEASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQL 412
+ ++ EL E + +L++ E+Q+ + L+ Q +L+Q E E K L
Sbjct: 292 QLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQL-----EEQEGQLKHL 346
Query: 413 ASEKEIQMQLQEEETLPGFQETLAEELRTSLRRMISDPVYFMERNYEM-----PRGDTSS 467
++ L+ +E G E +L+ L + P + E ++ G
Sbjct: 347 EQQEGQLEHLEHQEGQLGLPEQQVLQLK-QLEKQQGQPKHLEEEEGQLKHLVQQEGQLKH 405
Query: 468 L-RYDFRYSEDREQVRGFEAEEGLMLAADIMRGE----DFTPAEEFVPQEELGAAKKVPA 522
L + + + + QV E + G + + G+ + + VP++++G K +
Sbjct: 406 LVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQ 465
Query: 523 EEGVMEEAELVSEETEGWEEVELELD 548
EE +E E + + E+ E +L+
Sbjct: 466 EEKQLELPEQQEGQVKHLEKQEAQLE 491
Score = 57.8 bits (138), Expect = 3e-08
Identities = 85/362 (23%), Positives = 151/362 (41%), Gaps = 48/362 (13%)
Query: 262 EDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKL 321
E E E++++E +E E +Q+ E E+ Q A P+ + QEK
Sbjct: 72 EQECEQQQKEPQEQELQQQHWEQHEEYQKAEN------------------PEQQLKQEKT 113
Query: 322 RLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQ 381
+ ++ N QL EE LD D+E +++ EQ +Q+ EL E L++ E+Q+
Sbjct: 114 QRDQQLNKQLEEEKKLLDQQLDQE---LVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQE 170
Query: 382 QEVARLQAQVLKL----QQRCRMYGAETEKLQKQLASEKEIQMQLQEEE----TLPGFQE 433
++ + Q +L QQ ++ E ++ Q +L ++E Q++L E++ LP QE
Sbjct: 171 GQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQE 230
Query: 434 TLAEELRTSLRRM-ISDPVYFMERNYEMPRGDTSSLRYDFRYSEDRE----QVRGFEAEE 488
E + ++ +S+ E G L + E E Q++ E +E
Sbjct: 231 GQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQE 290
Query: 489 GLMLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGWEEVELELD 548
G ++ D + +P++++G K + +EG + E + E EE E +L
Sbjct: 291 GQ------LKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLK 344
Query: 549 EATRMNVVTSALEASGLGPSHLDMNYVLQ----QLANWQDAHYRR---QLRWKMLQKGEC 601
+ LE G L VLQ + Q H QL+ + Q+G+
Sbjct: 345 HLEQQEGQLEHLEHQE-GQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQL 403
Query: 602 PH 603
H
Sbjct: 404 KH 405
>gi|14165274 golgi-associated microtubule-binding protein HOOK3
[Homo sapiens]
Length = 718
Score = 59.7 bits (143), Expect = 8e-09
Identities = 66/275 (24%), Positives = 131/275 (47%), Gaps = 32/275 (11%)
Query: 234 SAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHP 293
SAKEEI H+++++ LQ +E E + E + ++ ED P
Sbjct: 190 SAKEEIAQRCHELDMQVAALQ--------EEKSSLLAENQVLMERLNQSDSIEDPNS--P 239
Query: 294 CDAPKLISQEALLH-QHHCPQLEALQEKLRL----LEEENHQLREEASQLDTLEDEEQML 348
L Q L Q +LEA ++ R+ LE+E +LR++ +L TL DE Q L
Sbjct: 240 AGRRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKEISELRQQNDELTTLADEAQSL 299
Query: 349 ILECVEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKL 408
E ++ +S ++++L ++E+Y+++ +++ L+ QV L+++ MY T L
Sbjct: 300 KDE-IDVLRHSSDKVSKLEG----QVESYKKKLEDLGDLRRQVKLLEEKNTMYMQNTVSL 354
Query: 409 QKQLASEKEIQMQLQE-EETLPGFQETLAEELRTSLR-----RMISDPVYFMERNYEMPR 462
+++L + QL+ + + Q L+EE + + + + + + V +++ + R
Sbjct: 355 EEELRKANAARSQLETYKRQVVELQNRLSEESKKADKLDFEYKRLKEKVDSLQKEKDRLR 414
Query: 463 GDTSSLRYDFRYSEDREQVRGFEAEEGLMLAADIM 497
+ SL+ E E++R +A+EG + +M
Sbjct: 415 TERDSLK------ETIEELRCVQAQEGQLTTQGLM 443
Score = 35.4 bits (80), Expect = 0.16
Identities = 40/169 (23%), Positives = 79/169 (46%), Gaps = 22/169 (13%)
Query: 200 RERDLNTAAR-IGQSLVKQNSV-------LMEENSKLE--ALLGSAKEEILYLRHQVN-- 247
R+ +L T R + Q L++ S L ++ SK E LL EE L H+ N
Sbjct: 502 RKNELETENRLVNQRLLEVQSQVEELQKSLQDQGSKAEDSVLLKKKLEEHLEKLHEANNE 561
Query: 248 ------LRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLIS 301
+ ++L +++S + E+ +E +KE E +Q EE ++ L+ A + +
Sbjct: 562 LQKKRAIIEDLEPRFNNSSLKIEELQEALRKKEEEMKQMEERYKKYLEKAKSV----IRT 617
Query: 302 QEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLIL 350
+ +Q P+++AL+ +L+ + H L +E + + + E+ I+
Sbjct: 618 LDPKQNQGAAPEIQALKNQLQERDRLFHSLEKEYEKTKSQREMEEKYIV 666
>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 479
Score = 59.3 bits (142), Expect = 1e-08
Identities = 65/259 (25%), Positives = 117/259 (45%), Gaps = 14/259 (5%)
Query: 202 RDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDE 261
++L + R Q+ V+ N +L N + E L +E + +++ ++E L +
Sbjct: 171 KELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEERLCEQEERLC 230
Query: 262 EDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLI--SQEALLHQHHCPQLEALQE 319
E E+ E+EE+ E+E+ E EE L C+ + + +E L Q P E L E
Sbjct: 231 EQEERLREQEERLREQEERLHEQEERL-----CEQEERLCEQEERLCEQEKLPGQERLLE 285
Query: 320 KL-RLLEEENHQLREE--ASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVL---- 372
++ +LLE+E Q +E + L++ E++L E + Q E Q L E+ L
Sbjct: 286 EVEKLLEQERRQEEQERLLERERLLDEVEELLEQERLRQQDERLWQQETLRELERLRELE 345
Query: 373 RLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPGFQ 432
RL ER ++ L+ L ++ + E+L + S +++ Q++E E G +
Sbjct: 346 RLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAE 405
Query: 433 ETLAEELRTSLRRMISDPV 451
E E + R + PV
Sbjct: 406 EPRGSESAAAARPVPGAPV 424
Score = 58.5 bits (140), Expect = 2e-08
Identities = 84/339 (24%), Positives = 144/339 (42%), Gaps = 56/339 (16%)
Query: 199 QRERDLNTAARIGQSLVKQNSVLMEE--------NSKLEALLGSA---KEEILYLRHQVN 247
+++ +++ ++G+SL K + E SK+E L ++E+ + Q+
Sbjct: 122 EKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQ 181
Query: 248 LRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLH 307
E Q+ S + E+ E+EE+ E+E+ E EE L
Sbjct: 182 AEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEERL------------------- 222
Query: 308 QHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELS 367
C Q E L E+ L E+ +LRE+ +L E++ + E E+ E +++ E
Sbjct: 223 ---CEQEERLCEQEERLREQEERLREQEERL----HEQEERLCEQEERLCEQEERLCEQE 275
Query: 368 EVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEET 427
+L ER +EV +L Q + +++ R+ E E+L ++ E + Q++E
Sbjct: 276 -----KLPGQERLLEEVEKLLEQERRQEEQERL--LERERLLDEVEELLEQERLRQQDER 328
Query: 428 LPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEA- 486
L QETL E R LR + + + +ER E+ R L ++ Y + E GFE
Sbjct: 329 L-WQQETLRELER--LREL--ERLRELERLRELER--MLELGWEALYEQRAEPRSGFEEL 381
Query: 487 ----EEGLMLAADIMRGEDFTPAEEFVPQEELGAAKKVP 521
+ L L + E AEE E AA+ VP
Sbjct: 382 NNENKSTLQLEQQVKELEKSGGAEEPRGSESAAAARPVP 420
Score = 42.7 bits (99), Expect = 0.001
Identities = 52/250 (20%), Positives = 99/250 (39%), Gaps = 21/250 (8%)
Query: 332 REEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQAQV 391
R ++ L LE + Q L + + SQ ++ ++ E + + V +L +
Sbjct: 78 RASSTTLQDLESQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSL 137
Query: 392 LKLQQ---------------RCRMYGAETEKLQKQLASE-KEIQMQLQEEETLPGFQETL 435
KL+ + ET L+K+L S +++Q +++ + L
Sbjct: 138 FKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQ 197
Query: 436 AEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAEEGLMLAAD 495
E LR R+ E+ + + + R E E++R E EE L +
Sbjct: 198 EERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQEERLR--EQEERLHEQEE 255
Query: 496 IMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGWEEVELELDEATRMNV 555
+ ++ E+ +E L +K+P +E ++EE E + E+ EE E L+ ++
Sbjct: 256 RLCEQEERLCEQ---EERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLDE 312
Query: 556 VTSALEASGL 565
V LE L
Sbjct: 313 VEELLEQERL 322
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 58.9 bits (141), Expect = 1e-08
Identities = 83/362 (22%), Positives = 163/362 (45%), Gaps = 42/362 (11%)
Query: 216 KQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEA 275
+Q + + +L +E+ LR Q LR++ Q+ ++ E EE+ E++E
Sbjct: 311 EQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEK 370
Query: 276 EEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLE---EENHQLR 332
QEE E++ Q K+ QE + + +L +E++R E E+ ++R
Sbjct: 371 MWRQEERLWEQEKQMRE--QEQKMRDQEERMWEQD-ERLREKEERMREQEKMWEQVEKMR 427
Query: 333 EEASQLD----TLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQ-----QQE 383
EE + T + EE+M + E+ E ++M E E + + E ++Q +QE
Sbjct: 428 EEKKMQEQEKKTRDQEEKM---QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 484
Query: 384 VARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPGFQETL--AEELRT 441
Q Q L +Q+ +++ E EK+Q+Q E + +++++E + G ++ + E++R
Sbjct: 485 EKEWQQQRLP-EQKEKLW--EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 541
Query: 442 SLRRM---------ISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAEEGLML 492
+M ++ E E + +D + + RE+ R E E+ +
Sbjct: 542 QEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWD-QEEKMREEERMREREKKMRE 600
Query: 493 AADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEG-WEEVELELDEAT 551
++MR ++ E+ QEE K EE + E+ E + E+ E WE+ E ++
Sbjct: 601 EEEMMREQE----EKMQEQEE----KMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 652
Query: 552 RM 553
+M
Sbjct: 653 KM 654
Score = 58.5 bits (140), Expect = 2e-08
Identities = 85/341 (24%), Positives = 151/341 (44%), Gaps = 50/341 (14%)
Query: 222 MEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEE 281
M E ++ +EE +R Q +E +Q + +E E++ E+EEK +EQEE
Sbjct: 585 MREEERMREREKKMREEEEMMREQ----EEKMQEQEEKMQEQEEKMWEQEEKM--QEQEE 638
Query: 282 E--EAEEDL--QCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQ 337
+ E EE + Q + +L Q+ L +H E +QE+ ++ E+E +E +
Sbjct: 639 KMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEH-----EKMQEQEKMQEQEEKIWEQEKME 693
Query: 338 LDTLEDEEQMLILECV---EQFSEASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKL 394
T E E++ E + E E ++M E E++ R+Q+E ++Q Q K+
Sbjct: 694 KKTQEQEKKTWDQEKMREEESMREREKKMREEEEMM--------REQEE--KMQEQEEKM 743
Query: 395 QQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPGFQETLAEELRTSLRRMISDPVYFM 454
Q++ + EK+ +Q + ++ E++ LP +E L E + + I + M
Sbjct: 744 QEQEEEMWEQEEKMWEQ-------EEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKM 796
Query: 455 ERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAEEGLMLAADIMRGEDFTPAEEFVPQEEL 514
E RG +R E++RG EE + + M G++ E+ QEE
Sbjct: 797 RDQEEKMRGQEEKMR------GQEEKMRG--QEEKMWGQEEKMWGQE----EKMWGQEEK 844
Query: 515 GAAKKVPAEEGVMEEAELVSEETE---GWEEVELELDEATR 552
++ EE + + E + E+ E G EE E +E R
Sbjct: 845 MWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMR 885
Score = 55.1 bits (131), Expect = 2e-07
Identities = 93/418 (22%), Positives = 174/418 (41%), Gaps = 46/418 (11%)
Query: 153 ELEEALCPNLPPPVKKITQEDVKVMLYLLEE---LLPPVWESVTYGMVLQRERDLNTAA- 208
EL+E L L K Q +VK + LE LLP V + + ++E +L
Sbjct: 229 ELQEKL--PLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEK 286
Query: 209 ----------RIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSD 258
R + L +Q + E+ K+ +E+ LR Q E +L
Sbjct: 287 KIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQ 346
Query: 259 SDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALL---HQHHCPQLE 315
++ E EE+ E++E EQEE+ ++ +L QE + Q Q E
Sbjct: 347 EEQMQEQEEKMWEQEEKMREQEEKMWRQE---------ERLWEQEKQMREQEQKMRDQEE 397
Query: 316 ALQEKLRLLEEENHQLREEASQLDTLED-EEQMLILECVEQFSEASQQMAELSEVLVLRL 374
+ E+ L E+ ++RE+ + +E E+ + E ++ + ++M E E +
Sbjct: 398 RMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQE--EERIRER 455
Query: 375 ENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPGFQET 434
E R+++E R Q + ++ Q+ E E Q++L +KE +L E+E + +E
Sbjct: 456 EKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKE---KLWEQEKMQEQEEK 512
Query: 435 LAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSED---REQVRGFEAEEGLM 491
+ E+ I D + +M R + + D + ++ R+Q + +E M
Sbjct: 513 IWEQ-----EEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERM 567
Query: 492 LAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGWEEVELELDE 549
+ + EE + +EE + E+ + EE E++ E+ E +E E ++ E
Sbjct: 568 EKKTQEQEKKTWDQEEKMREEE----RMREREKKMREEEEMMREQEEKMQEQEEKMQE 621
Score = 53.1 bits (126), Expect = 7e-07
Identities = 78/368 (21%), Positives = 150/368 (40%), Gaps = 35/368 (9%)
Query: 212 QSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEE 271
Q + Q + E++ +L +E+ +R+E + D++E+ +EE
Sbjct: 390 QKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEE 449
Query: 272 EKEAEEEQEEEEAEEDL-----------------------QCAHPCDAPKLISQEALLHQ 308
E+ E E++ E EE + Q P KL QE + Q
Sbjct: 450 ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 509
Query: 309 HHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSE 368
++ +EK+R EE Q ++ Q E E+QM E E+ + Q+M + E
Sbjct: 510 EE--KIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQM--WEQEEKMRDQEQKMWDQEE 565
Query: 369 VLVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETL 428
+ + + E++ + + ++++R + E E +++Q +E + ++QE+E
Sbjct: 566 RMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEK 625
Query: 429 PGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAEE 488
QE +E + E+ +E R + + + + +EQ + E EE
Sbjct: 626 MWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL-WEHEKMQEQEKMQEQEE 684
Query: 489 GL----MLAADIMRGEDFTPAEEFVPQEE--LGAAKKVPAEEGVM-EEAELVSEETEGWE 541
+ + E T +E + +EE KK+ EE +M E+ E + E+ E +
Sbjct: 685 KIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQ 744
Query: 542 EVELELDE 549
E E E+ E
Sbjct: 745 EQEEEMWE 752
Score = 34.7 bits (78), Expect = 0.27
Identities = 53/238 (22%), Positives = 103/238 (43%), Gaps = 22/238 (9%)
Query: 324 LEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQE 383
L+++N +L+E+ ++ + E Q+ + E + A L +V L+ +Q+E
Sbjct: 223 LKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFL---LPQVQTNTLQEEMWRQEE 279
Query: 384 VARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQE------EETLPGFQETLAE 437
R Q + ++ Q+ E + Q+ E+E +M QE E+ L ++ L E
Sbjct: 280 ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELRE 339
Query: 438 --ELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAEEGLMLAAD 495
ELR +M E+ +M + R + R E +Q+R E E+ + +
Sbjct: 340 QKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMR--EQEQKMRDQEE 397
Query: 496 IMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGWEEVELELDEATRM 553
M +D E +EE ++ +E + E+ E + EE + E+ + D+ +M
Sbjct: 398 RMWEQD----ERLREKEE-----RMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKM 446
Score = 32.0 bits (71), Expect = 1.7
Identities = 37/209 (17%), Positives = 93/209 (44%), Gaps = 30/209 (14%)
Query: 221 LMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQE 280
+ EE S E +EE + + ++++ ++ +E E EE+ E++E EQ+
Sbjct: 709 MREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQ 768
Query: 281 EEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLEEENHQLREE---ASQ 337
+L Q+ L +H E +QE+ ++ E+E +E Q
Sbjct: 769 -----------------RLPEQKEKLWEH-----EKMQEQEKIWEQEEKMRDQEEKMRGQ 806
Query: 338 LDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQR 397
+ + +E+ + + + + + + + ++ + + ++++ ++Q Q K++++
Sbjct: 807 EEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQ 866
Query: 398 CRMYGAETEKLQKQLASEKEIQMQLQEEE 426
+ EK++ E+E +M+ QEE+
Sbjct: 867 EEKMRGQEEKMR-----EQEEKMRGQEEK 890
>gi|119120918 coiled-coil domain containing 64 [Homo sapiens]
Length = 573
Score = 58.9 bits (141), Expect = 1e-08
Identities = 54/244 (22%), Positives = 115/244 (47%), Gaps = 13/244 (5%)
Query: 186 PPVWESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQ 245
PP + ++ Q+E+DL AAR+G++L+++N + + ++ L E + +H+
Sbjct: 92 PPSQDPELLSVIRQKEKDLVLAARLGKALLERNQDMSRQYEQMHKELTDKLEHLEQEKHE 151
Query: 246 VNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEAL 305
+ R E + + E E E + K+ ++E E ++ A + +S++
Sbjct: 152 LRRRFE----NREGEWEGRVSELESDVKQLQDELERQQIHLREADREKSRAVQELSEQ-- 205
Query: 306 LHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAE 365
+Q QL E R L + H LRE+ + ++ ++ + + + S + E
Sbjct: 206 -NQRLLDQLSRASEVERQLSMQVHALREDFREKNSSTNQHIIRLESLQAEIKMLSDRKRE 264
Query: 366 LSEVLVLRLENYERQQQEVARLQAQVLKLQQR-----CRMYGAETEKLQKQLASEKEIQM 420
L L LE + Q V LQ +VL L+++ +++ ++ E LQ+ S +++Q+
Sbjct: 265 LEHRLSATLEENDLLQGTVEELQDRVLILERQGHDKDLQLHQSQLE-LQEVRLSCRQLQV 323
Query: 421 QLQE 424
+++E
Sbjct: 324 KVEE 327
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 58.5 bits (140), Expect = 2e-08
Identities = 90/419 (21%), Positives = 184/419 (43%), Gaps = 60/419 (14%)
Query: 199 QRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSD 258
Q+ L + Q ++ + L E ++ L + K+E+ + H++ R E
Sbjct: 880 QKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLE------- 932
Query: 259 SDEEDEDEE-EEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEAL 317
+EED ++ + E +K A++ + EE E+ + A + ++ EA +++ L
Sbjct: 933 -EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA--------KIKKL 983
Query: 318 QEKLRLLEEENHQLREEASQLD--------TLEDEEQMLILECVEQFSEASQQMAELSEV 369
++++ +++++N++L +E L+ L +EE E + ++ + +
Sbjct: 984 EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE-----EKAKNLTKLKNKHESMISE 1038
Query: 370 LVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLP 429
L +RL+ E+ +QE+ +L+ KL+ + + LQ Q+A E++MQL ++E
Sbjct: 1039 LEVRLKKEEKSRQELEKLKR---KLEGDASDFHEQIADLQAQIA---ELKMQLAKKE--- 1089
Query: 430 GFQETLAEELRTSLRRM---ISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEA 486
EEL+ +L R+ I+ +++ E+ G S L+ D SE + + +
Sbjct: 1090 -------EELQAALARLDDEIAQKNNALKKIREL-EGHISDLQEDLD-SERAARNKAEKQ 1140
Query: 487 EEGLMLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGWEE--VE 544
+ L + ++ E + Q+EL A + E+ V + + EET E E
Sbjct: 1141 KRDLGEELEALKTELEDTLDSTATQQELRAKR----EQEVTVLKKALDEETRSHEAQVQE 1196
Query: 545 LELDEATRMNVVTSALEASGLGPSHLDMNYVLQQLANWQDAHYRRQLRWKMLQKGECPH 603
+ A + +T LE ++LD N +Q ++A +LR K E H
Sbjct: 1197 MRQKHAQAVEELTEQLEQFKRAKANLDKN---KQTLEKENADLAGELRVLGQAKQEVEH 1252
Score = 55.1 bits (131), Expect = 2e-07
Identities = 98/410 (23%), Positives = 167/410 (40%), Gaps = 57/410 (13%)
Query: 209 RIGQSLVKQNSVLMEENSKLEA---LLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDED 265
R +L K L +EN+ L +LG AK+E+ + + ++ + + LQ S D +
Sbjct: 1217 RAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ----SKCSDGE 1272
Query: 266 EEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLE 325
E + + Q E E+ + A KL A L LQ+ LL+
Sbjct: 1273 RARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ-------LQDTQELLQ 1325
Query: 326 EENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEVA 385
EE Q +++L LE+E L + +++ EA Q + L ++L + +++ Q+ A
Sbjct: 1326 EETRQKLNVSTKLRQLEEERNSL-QDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFA 1384
Query: 386 -----------RLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPGFQET 434
R Q ++ L Q+ A +KL+K ++ +Q +L + Q
Sbjct: 1385 STVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK---TKNRLQQELDDLVVDLDNQRQ 1441
Query: 435 LAEELRTSLRRMISDPVYFMERNY------EMPRGDTSSLRYDFR-YSEDREQVRGFEAE 487
L L R+ D + E+N E R + + + + S R EA+
Sbjct: 1442 LVSNLEKKQRKF--DQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAK 1499
Query: 488 EGL-----MLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGWEE 542
E L ML A++ ED +++ V + K A E MEE + EE E +E
Sbjct: 1500 EELERTNKMLKAEM---EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE--DE 1554
Query: 543 VELELDEATRMNVVTSALEASGLGPSHLDMNYVLQQLANWQDAHYRRQLR 592
++ D R+ V AL+ G D+ Q + Q+ RRQL+
Sbjct: 1555 LQATEDAKLRLEVNMQALK----GQFERDL-----QARDEQNEEKRRQLQ 1595
Score = 48.9 bits (115), Expect = 1e-05
Identities = 75/374 (20%), Positives = 147/374 (39%), Gaps = 56/374 (14%)
Query: 216 KQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEA 275
KQ ++ KLE G K+ L + R+E ++ + +D + E E+ A
Sbjct: 1610 KQRALAAAAKKKLE---GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARA 1666
Query: 276 EEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCP-----QLEALQEKL-------RL 323
++ A+E+ + A +A + QE L + E L E+L
Sbjct: 1667 SRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA 1726
Query: 324 LEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLR---------- 373
L++E +L +QL+ +EEQ + ++ +A+QQ +LS L
Sbjct: 1727 LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESA 1786
Query: 374 LENYERQQQE-------------------VARLQAQVLKL----QQRCRMYGAETEKLQK 410
+ ERQ +E +A L+A++ +L +Q R A T+ L++
Sbjct: 1787 RQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQ 1846
Query: 411 QLASEKEIQMQLQEEETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRY 470
+ KEI +Q+++E + + AE+ +++ + + E + + L+
Sbjct: 1847 KDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ-LKRQLEEAEEESQRINANRRKLQR 1905
Query: 471 DFRYSEDREQVRGFEAEEGLMLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEA 530
+ + + + G E L + + RG + FVP G + + +G EE
Sbjct: 1906 ELDEATESNEAMGREVN---ALKSKLRRGNE----TSFVPSRRSGGRRVIENADGSEEET 1958
Query: 531 ELVSEETEGWEEVE 544
+ + G + E
Sbjct: 1959 DTRDADFNGTKASE 1972
Score = 48.5 bits (114), Expect = 2e-05
Identities = 48/206 (23%), Positives = 92/206 (44%), Gaps = 16/206 (7%)
Query: 252 LLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHC 311
LLQ+ +E E+E ++ KE +++ E E E + + + + L+ ++
Sbjct: 844 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 903
Query: 312 PQLEALQEKLRLLEEENHQ-LREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVL 370
+ E ++ +L ++E + L E ++L+ ED Q L E + +QQM +L E L
Sbjct: 904 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAE----RKKMAQQMLDLEEQL 959
Query: 371 VLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQ--LASEK--EIQMQLQEEE 426
++ Q E +A++ KL+ + + KL K+ L E+ ++ L EEE
Sbjct: 960 EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE 1019
Query: 427 -------TLPGFQETLAEELRTSLRR 445
L E++ EL L++
Sbjct: 1020 EKAKNLTKLKNKHESMISELEVRLKK 1045
Score = 45.4 bits (106), Expect = 2e-04
Identities = 83/392 (21%), Positives = 156/392 (39%), Gaps = 58/392 (14%)
Query: 214 LVKQNSVLMEENSKLEALLGSAKEEI-----LYLRHQVNLRDELLQLYSDSDEEDEDEEE 268
L K L + +++ L ++E+ LR +VN++ Q D DE EE
Sbjct: 1530 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1589
Query: 269 EEEEKEAEEEQEEEEAEEDLQCAHPCDAPK-----------LISQEALL-HQHHCPQLEA 316
+ + + + + E E E++ + A K L + A+ + QL
Sbjct: 1590 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1649
Query: 317 LQEKLRLLEEE----------------NHQLREEASQLDTLEDEEQMLILECVEQFSEAS 360
LQ +++ + E ++ + ++ + D ++ +E + E + +A
Sbjct: 1650 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK--QAD 1707
Query: 361 QQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQ--------------RCRMYGAETE 406
+ EL+E L L Q E RL+A++ +L++ R R + E
Sbjct: 1708 LEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAE 1767
Query: 407 KLQKQLASEKEIQMQLQEEETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTS 466
+L +LA+E+ Q+ E+ E +ELR+ L M + +
Sbjct: 1768 QLSNELATERS---TAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIA 1824
Query: 467 SLRYDFRYSEDREQVRGFEA--EEGLMLAADIMRGEDFTP-AEEFVPQEELGAAKKVPAE 523
L E RE+ ++ ++ L +++ ED AE++ Q E G A +V
Sbjct: 1825 QLEEQVE-QEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNA-RVKQL 1882
Query: 524 EGVMEEAELVSEE-TEGWEEVELELDEATRMN 554
+ +EEAE S+ +++ ELDEAT N
Sbjct: 1883 KRQLEEAEEESQRINANRRKLQRELDEATESN 1914
Score = 44.7 bits (104), Expect = 3e-04
Identities = 67/295 (22%), Positives = 126/295 (42%), Gaps = 28/295 (9%)
Query: 150 FIRELEEALCPNLPPPVKKITQEDVKVMLYLLEELLPPVWESVTYGMVLQRERDLNT--- 206
F RELE+A + +E+ K L +L+ + E + +++ DL
Sbjct: 1657 FQRELEDARASR--DEIFATAKENEKKAKSLEADLMQ-LQEDLAAAERARKQADLEKEEL 1713
Query: 207 AARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDE----- 261
A + SL +N+ L +E +LEA + +EE L +E + + SD
Sbjct: 1714 AEELASSLSGRNA-LQDEKRRLEARIAQLEEE---------LEEEQGNMEAMSDRVRKAT 1763
Query: 262 EDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKL 321
+ ++ E E Q+ E A + L+ + KL E + + AL+ K+
Sbjct: 1764 QQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKI 1823
Query: 322 RLLEEE-NHQLREEASQLDTLEDEEQML--ILECVEQFSEASQQMAELSEVLVLRLENYE 378
LEE+ + RE+ + +L+ +++ L IL VE + ++Q E +E R++ +
Sbjct: 1824 AQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLK 1883
Query: 379 RQ----QQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLP 429
RQ ++E R+ A KLQ+ E + +++ + K + E +P
Sbjct: 1884 RQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVP 1938
Score = 40.0 bits (92), Expect = 0.006
Identities = 37/139 (26%), Positives = 63/139 (45%), Gaps = 7/139 (5%)
Query: 318 QEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVL---VLRL 374
+ +L+ LE+++ QL EE + L E L E E + + EL E+L RL
Sbjct: 872 ENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARL 931
Query: 375 ENYE----RQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPG 430
E E + Q E ++ Q+L L+++ A +KLQ + + + +L++E +
Sbjct: 932 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD 991
Query: 431 FQETLAEELRTSLRRMISD 449
Q + R L ISD
Sbjct: 992 DQNNKLSKERKLLEERISD 1010
Score = 35.0 bits (79), Expect = 0.20
Identities = 56/257 (21%), Positives = 109/257 (42%), Gaps = 23/257 (8%)
Query: 199 QRERDLNTA-ARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYS 257
++E +L A AR+ + ++N+ L ++ +LE + +E++ R N ++ +
Sbjct: 1087 KKEEELQAALARLDDEIAQKNNAL-KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLG 1145
Query: 258 DSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEAL 317
+ E + E E+ + A +++ + E+++ + S EA + + +A+
Sbjct: 1146 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1205
Query: 318 QEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENY 377
+E LE+ TLE E L E + +A Q++ + L +++
Sbjct: 1206 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGE-LRVLGQAKQEVEHKKKKLEAQVQEL 1264
Query: 378 ERQ----QQEVARLQAQVLKLQQRCR-MYGAETE------KLQKQLASEKEIQMQLQEEE 426
+ + ++ A L +V KLQ + G E KL K +AS + QLQ+
Sbjct: 1265 QSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVAS---LSSQLQDT- 1320
Query: 427 TLPGFQETLAEELRTSL 443
QE L EE R L
Sbjct: 1321 -----QELLQEETRQKL 1332
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 58.5 bits (140), Expect = 2e-08
Identities = 90/419 (21%), Positives = 184/419 (43%), Gaps = 60/419 (14%)
Query: 199 QRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSD 258
Q+ L + Q ++ + L E ++ L + K+E+ + H++ R E
Sbjct: 887 QKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLE------- 939
Query: 259 SDEEDEDEE-EEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEAL 317
+EED ++ + E +K A++ + EE E+ + A + ++ EA +++ L
Sbjct: 940 -EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA--------KIKKL 990
Query: 318 QEKLRLLEEENHQLREEASQLD--------TLEDEEQMLILECVEQFSEASQQMAELSEV 369
++++ +++++N++L +E L+ L +EE E + ++ + +
Sbjct: 991 EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE-----EKAKNLTKLKNKHESMISE 1045
Query: 370 LVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLP 429
L +RL+ E+ +QE+ +L+ KL+ + + LQ Q+A E++MQL ++E
Sbjct: 1046 LEVRLKKEEKSRQELEKLKR---KLEGDASDFHEQIADLQAQIA---ELKMQLAKKE--- 1096
Query: 430 GFQETLAEELRTSLRRM---ISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEA 486
EEL+ +L R+ I+ +++ E+ G S L+ D SE + + +
Sbjct: 1097 -------EELQAALARLDDEIAQKNNALKKIREL-EGHISDLQEDLD-SERAARNKAEKQ 1147
Query: 487 EEGLMLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGWEE--VE 544
+ L + ++ E + Q+EL A + E+ V + + EET E E
Sbjct: 1148 KRDLGEELEALKTELEDTLDSTATQQELRAKR----EQEVTVLKKALDEETRSHEAQVQE 1203
Query: 545 LELDEATRMNVVTSALEASGLGPSHLDMNYVLQQLANWQDAHYRRQLRWKMLQKGECPH 603
+ A + +T LE ++LD N +Q ++A +LR K E H
Sbjct: 1204 MRQKHAQAVEELTEQLEQFKRAKANLDKN---KQTLEKENADLAGELRVLGQAKQEVEH 1259
Score = 55.1 bits (131), Expect = 2e-07
Identities = 98/410 (23%), Positives = 167/410 (40%), Gaps = 57/410 (13%)
Query: 209 RIGQSLVKQNSVLMEENSKLEA---LLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDED 265
R +L K L +EN+ L +LG AK+E+ + + ++ + + LQ S D +
Sbjct: 1224 RAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ----SKCSDGE 1279
Query: 266 EEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLE 325
E + + Q E E+ + A KL A L LQ+ LL+
Sbjct: 1280 RARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ-------LQDTQELLQ 1332
Query: 326 EENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEVA 385
EE Q +++L LE+E L + +++ EA Q + L ++L + +++ Q+ A
Sbjct: 1333 EETRQKLNVSTKLRQLEEERNSL-QDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFA 1391
Query: 386 -----------RLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPGFQET 434
R Q ++ L Q+ A +KL+K ++ +Q +L + Q
Sbjct: 1392 STVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK---TKNRLQQELDDLVVDLDNQRQ 1448
Query: 435 LAEELRTSLRRMISDPVYFMERNY------EMPRGDTSSLRYDFR-YSEDREQVRGFEAE 487
L L R+ D + E+N E R + + + + S R EA+
Sbjct: 1449 LVSNLEKKQRKF--DQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAK 1506
Query: 488 EGL-----MLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGWEE 542
E L ML A++ ED +++ V + K A E MEE + EE E +E
Sbjct: 1507 EELERTNKMLKAEM---EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE--DE 1561
Query: 543 VELELDEATRMNVVTSALEASGLGPSHLDMNYVLQQLANWQDAHYRRQLR 592
++ D R+ V AL+ G D+ Q + Q+ RRQL+
Sbjct: 1562 LQATEDAKLRLEVNMQALK----GQFERDL-----QARDEQNEEKRRQLQ 1602
Score = 48.9 bits (115), Expect = 1e-05
Identities = 75/374 (20%), Positives = 147/374 (39%), Gaps = 56/374 (14%)
Query: 216 KQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEA 275
KQ ++ KLE G K+ L + R+E ++ + +D + E E+ A
Sbjct: 1617 KQRALAAAAKKKLE---GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARA 1673
Query: 276 EEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCP-----QLEALQEKL-------RL 323
++ A+E+ + A +A + QE L + E L E+L
Sbjct: 1674 SRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA 1733
Query: 324 LEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLR---------- 373
L++E +L +QL+ +EEQ + ++ +A+QQ +LS L
Sbjct: 1734 LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESA 1793
Query: 374 LENYERQQQE-------------------VARLQAQVLKL----QQRCRMYGAETEKLQK 410
+ ERQ +E +A L+A++ +L +Q R A T+ L++
Sbjct: 1794 RQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQ 1853
Query: 411 QLASEKEIQMQLQEEETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRY 470
+ KEI +Q+++E + + AE+ +++ + + E + + L+
Sbjct: 1854 KDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ-LKRQLEEAEEESQRINANRRKLQR 1912
Query: 471 DFRYSEDREQVRGFEAEEGLMLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEA 530
+ + + + G E L + + RG + FVP G + + +G EE
Sbjct: 1913 ELDEATESNEAMGREVN---ALKSKLRRGNE----TSFVPSRRSGGRRVIENADGSEEET 1965
Query: 531 ELVSEETEGWEEVE 544
+ + G + E
Sbjct: 1966 DTRDADFNGTKASE 1979
Score = 48.5 bits (114), Expect = 2e-05
Identities = 48/206 (23%), Positives = 92/206 (44%), Gaps = 16/206 (7%)
Query: 252 LLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHC 311
LLQ+ +E E+E ++ KE +++ E E E + + + + L+ ++
Sbjct: 851 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 910
Query: 312 PQLEALQEKLRLLEEENHQ-LREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVL 370
+ E ++ +L ++E + L E ++L+ ED Q L E + +QQM +L E L
Sbjct: 911 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAE----RKKMAQQMLDLEEQL 966
Query: 371 VLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQ--LASEK--EIQMQLQEEE 426
++ Q E +A++ KL+ + + KL K+ L E+ ++ L EEE
Sbjct: 967 EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE 1026
Query: 427 -------TLPGFQETLAEELRTSLRR 445
L E++ EL L++
Sbjct: 1027 EKAKNLTKLKNKHESMISELEVRLKK 1052
Score = 45.4 bits (106), Expect = 2e-04
Identities = 83/392 (21%), Positives = 156/392 (39%), Gaps = 58/392 (14%)
Query: 214 LVKQNSVLMEENSKLEALLGSAKEEI-----LYLRHQVNLRDELLQLYSDSDEEDEDEEE 268
L K L + +++ L ++E+ LR +VN++ Q D DE EE
Sbjct: 1537 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1596
Query: 269 EEEEKEAEEEQEEEEAEEDLQCAHPCDAPK-----------LISQEALL-HQHHCPQLEA 316
+ + + + + E E E++ + A K L + A+ + QL
Sbjct: 1597 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1656
Query: 317 LQEKLRLLEEE----------------NHQLREEASQLDTLEDEEQMLILECVEQFSEAS 360
LQ +++ + E ++ + ++ + D ++ +E + E + +A
Sbjct: 1657 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK--QAD 1714
Query: 361 QQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQ--------------RCRMYGAETE 406
+ EL+E L L Q E RL+A++ +L++ R R + E
Sbjct: 1715 LEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAE 1774
Query: 407 KLQKQLASEKEIQMQLQEEETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTS 466
+L +LA+E+ Q+ E+ E +ELR+ L M + +
Sbjct: 1775 QLSNELATERS---TAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIA 1831
Query: 467 SLRYDFRYSEDREQVRGFEA--EEGLMLAADIMRGEDFTP-AEEFVPQEELGAAKKVPAE 523
L E RE+ ++ ++ L +++ ED AE++ Q E G A +V
Sbjct: 1832 QLEEQVE-QEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNA-RVKQL 1889
Query: 524 EGVMEEAELVSEE-TEGWEEVELELDEATRMN 554
+ +EEAE S+ +++ ELDEAT N
Sbjct: 1890 KRQLEEAEEESQRINANRRKLQRELDEATESN 1921
Score = 44.7 bits (104), Expect = 3e-04
Identities = 67/295 (22%), Positives = 126/295 (42%), Gaps = 28/295 (9%)
Query: 150 FIRELEEALCPNLPPPVKKITQEDVKVMLYLLEELLPPVWESVTYGMVLQRERDLNT--- 206
F RELE+A + +E+ K L +L+ + E + +++ DL
Sbjct: 1664 FQRELEDARASR--DEIFATAKENEKKAKSLEADLMQ-LQEDLAAAERARKQADLEKEEL 1720
Query: 207 AARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDE----- 261
A + SL +N+ L +E +LEA + +EE L +E + + SD
Sbjct: 1721 AEELASSLSGRNA-LQDEKRRLEARIAQLEEE---------LEEEQGNMEAMSDRVRKAT 1770
Query: 262 EDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKL 321
+ ++ E E Q+ E A + L+ + KL E + + AL+ K+
Sbjct: 1771 QQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKI 1830
Query: 322 RLLEEE-NHQLREEASQLDTLEDEEQML--ILECVEQFSEASQQMAELSEVLVLRLENYE 378
LEE+ + RE+ + +L+ +++ L IL VE + ++Q E +E R++ +
Sbjct: 1831 AQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLK 1890
Query: 379 RQ----QQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLP 429
RQ ++E R+ A KLQ+ E + +++ + K + E +P
Sbjct: 1891 RQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVP 1945
Score = 40.0 bits (92), Expect = 0.006
Identities = 37/139 (26%), Positives = 63/139 (45%), Gaps = 7/139 (5%)
Query: 318 QEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVL---VLRL 374
+ +L+ LE+++ QL EE + L E L E E + + EL E+L RL
Sbjct: 879 ENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARL 938
Query: 375 ENYE----RQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPG 430
E E + Q E ++ Q+L L+++ A +KLQ + + + +L++E +
Sbjct: 939 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD 998
Query: 431 FQETLAEELRTSLRRMISD 449
Q + R L ISD
Sbjct: 999 DQNNKLSKERKLLEERISD 1017
Score = 35.0 bits (79), Expect = 0.20
Identities = 56/257 (21%), Positives = 109/257 (42%), Gaps = 23/257 (8%)
Query: 199 QRERDLNTA-ARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYS 257
++E +L A AR+ + ++N+ L ++ +LE + +E++ R N ++ +
Sbjct: 1094 KKEEELQAALARLDDEIAQKNNAL-KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLG 1152
Query: 258 DSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEAL 317
+ E + E E+ + A +++ + E+++ + S EA + + +A+
Sbjct: 1153 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1212
Query: 318 QEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENY 377
+E LE+ TLE E L E + +A Q++ + L +++
Sbjct: 1213 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGE-LRVLGQAKQEVEHKKKKLEAQVQEL 1271
Query: 378 ERQ----QQEVARLQAQVLKLQQRCR-MYGAETE------KLQKQLASEKEIQMQLQEEE 426
+ + ++ A L +V KLQ + G E KL K +AS + QLQ+
Sbjct: 1272 QSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVAS---LSSQLQDT- 1327
Query: 427 TLPGFQETLAEELRTSL 443
QE L EE R L
Sbjct: 1328 -----QELLQEETRQKL 1339
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 58.5 bits (140), Expect = 2e-08
Identities = 90/419 (21%), Positives = 184/419 (43%), Gaps = 60/419 (14%)
Query: 199 QRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSD 258
Q+ L + Q ++ + L E ++ L + K+E+ + H++ R E
Sbjct: 887 QKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLE------- 939
Query: 259 SDEEDEDEE-EEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEAL 317
+EED ++ + E +K A++ + EE E+ + A + ++ EA +++ L
Sbjct: 940 -EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA--------KIKKL 990
Query: 318 QEKLRLLEEENHQLREEASQLD--------TLEDEEQMLILECVEQFSEASQQMAELSEV 369
++++ +++++N++L +E L+ L +EE E + ++ + +
Sbjct: 991 EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE-----EKAKNLTKLKNKHESMISE 1045
Query: 370 LVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLP 429
L +RL+ E+ +QE+ +L+ KL+ + + LQ Q+A E++MQL ++E
Sbjct: 1046 LEVRLKKEEKSRQELEKLKR---KLEGDASDFHEQIADLQAQIA---ELKMQLAKKE--- 1096
Query: 430 GFQETLAEELRTSLRRM---ISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEA 486
EEL+ +L R+ I+ +++ E+ G S L+ D SE + + +
Sbjct: 1097 -------EELQAALARLDDEIAQKNNALKKIREL-EGHISDLQEDLD-SERAARNKAEKQ 1147
Query: 487 EEGLMLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGWEE--VE 544
+ L + ++ E + Q+EL A + E+ V + + EET E E
Sbjct: 1148 KRDLGEELEALKTELEDTLDSTATQQELRAKR----EQEVTVLKKALDEETRSHEAQVQE 1203
Query: 545 LELDEATRMNVVTSALEASGLGPSHLDMNYVLQQLANWQDAHYRRQLRWKMLQKGECPH 603
+ A + +T LE ++LD N +Q ++A +LR K E H
Sbjct: 1204 MRQKHAQAVEELTEQLEQFKRAKANLDKN---KQTLEKENADLAGELRVLGQAKQEVEH 1259
Score = 55.1 bits (131), Expect = 2e-07
Identities = 98/410 (23%), Positives = 167/410 (40%), Gaps = 57/410 (13%)
Query: 209 RIGQSLVKQNSVLMEENSKLEA---LLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDED 265
R +L K L +EN+ L +LG AK+E+ + + ++ + + LQ S D +
Sbjct: 1224 RAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ----SKCSDGE 1279
Query: 266 EEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLE 325
E + + Q E E+ + A KL A L LQ+ LL+
Sbjct: 1280 RARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ-------LQDTQELLQ 1332
Query: 326 EENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEVA 385
EE Q +++L LE+E L + +++ EA Q + L ++L + +++ Q+ A
Sbjct: 1333 EETRQKLNVSTKLRQLEEERNSL-QDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFA 1391
Query: 386 -----------RLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPGFQET 434
R Q ++ L Q+ A +KL+K ++ +Q +L + Q
Sbjct: 1392 STVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK---TKNRLQQELDDLVVDLDNQRQ 1448
Query: 435 LAEELRTSLRRMISDPVYFMERNY------EMPRGDTSSLRYDFR-YSEDREQVRGFEAE 487
L L R+ D + E+N E R + + + + S R EA+
Sbjct: 1449 LVSNLEKKQRKF--DQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAK 1506
Query: 488 EGL-----MLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGWEE 542
E L ML A++ ED +++ V + K A E MEE + EE E +E
Sbjct: 1507 EELERTNKMLKAEM---EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE--DE 1561
Query: 543 VELELDEATRMNVVTSALEASGLGPSHLDMNYVLQQLANWQDAHYRRQLR 592
++ D R+ V AL+ G D+ Q + Q+ RRQL+
Sbjct: 1562 LQATEDAKLRLEVNMQALK----GQFERDL-----QARDEQNEEKRRQLQ 1602
Score = 48.5 bits (114), Expect = 2e-05
Identities = 48/206 (23%), Positives = 92/206 (44%), Gaps = 16/206 (7%)
Query: 252 LLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHC 311
LLQ+ +E E+E ++ KE +++ E E E + + + + L+ ++
Sbjct: 851 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 910
Query: 312 PQLEALQEKLRLLEEENHQ-LREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVL 370
+ E ++ +L ++E + L E ++L+ ED Q L E + +QQM +L E L
Sbjct: 911 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAE----RKKMAQQMLDLEEQL 966
Query: 371 VLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQ--LASEK--EIQMQLQEEE 426
++ Q E +A++ KL+ + + KL K+ L E+ ++ L EEE
Sbjct: 967 EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE 1026
Query: 427 -------TLPGFQETLAEELRTSLRR 445
L E++ EL L++
Sbjct: 1027 EKAKNLTKLKNKHESMISELEVRLKK 1052
Score = 45.8 bits (107), Expect = 1e-04
Identities = 87/409 (21%), Positives = 163/409 (39%), Gaps = 62/409 (15%)
Query: 214 LVKQNSVLMEENSKLEALLGSAKEEI-----LYLRHQVNLRDELLQLYSDSDEEDEDEEE 268
L K L + +++ L ++E+ LR +VN++ Q D DE EE
Sbjct: 1537 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1596
Query: 269 EEEEKEAEEEQEEEEAEEDLQCAHPCDAPK-----------LISQEALL-HQHHCPQLEA 316
+ + + + + E E E++ + A K L + A+ + QL
Sbjct: 1597 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1656
Query: 317 LQEKLRLLEEE----------------NHQLREEASQLDTLEDEEQMLILECVEQFSEAS 360
LQ +++ + E ++ + ++ + D ++ +E + E + +A
Sbjct: 1657 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK--QAD 1714
Query: 361 QQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQ--------------RCRMYGAETE 406
+ EL+E L L Q E RL+A++ +L++ R R + E
Sbjct: 1715 LEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAE 1774
Query: 407 KLQKQLASEKEIQMQLQEEETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTS 466
+L +LA+E+ Q+ E+ E +ELR+ L M + +
Sbjct: 1775 QLSNELATERS---TAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIA 1831
Query: 467 SLRYDFRYSEDREQVRGFEA--EEGLMLAADIMRGEDFTP-AEEFVPQEELGAAKKVPAE 523
L E RE+ ++ ++ L +++ ED AE++ Q E G A +V
Sbjct: 1832 QLEEQVE-QEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNA-RVKQL 1889
Query: 524 EGVMEEAELVSEE-TEGWEEVELELDEATRMNVV----TSALEASGLGP 567
+ +EEAE S+ +++ ELDEAT N +AL++ GP
Sbjct: 1890 KRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRGP 1938
Score = 44.3 bits (103), Expect = 3e-04
Identities = 63/262 (24%), Positives = 115/262 (43%), Gaps = 28/262 (10%)
Query: 150 FIRELEEALCPNLPPPVKKITQEDVKVMLYLLEELLPPVWESVTYGMVLQRERDLNT--- 206
F RELE+A + +E+ K L +L+ + E + +++ DL
Sbjct: 1664 FQRELEDARASR--DEIFATAKENEKKAKSLEADLMQ-LQEDLAAAERARKQADLEKEEL 1720
Query: 207 AARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDE----- 261
A + SL +N+ L +E +LEA + +EE L +E + + SD
Sbjct: 1721 AEELASSLSGRNA-LQDEKRRLEARIAQLEEE---------LEEEQGNMEAMSDRVRKAT 1770
Query: 262 EDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKL 321
+ ++ E E Q+ E A + L+ + KL E + + AL+ K+
Sbjct: 1771 QQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKI 1830
Query: 322 RLLEEE-NHQLREEASQLDTLEDEEQML--ILECVEQFSEASQQMAELSEVLVLRLENYE 378
LEE+ + RE+ + +L+ +++ L IL VE + ++Q E +E R++ +
Sbjct: 1831 AQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLK 1890
Query: 379 RQ----QQEVARLQAQVLKLQQ 396
RQ ++E R+ A KLQ+
Sbjct: 1891 RQLEEAEEESQRINANRRKLQR 1912
Score = 40.0 bits (92), Expect = 0.006
Identities = 37/139 (26%), Positives = 63/139 (45%), Gaps = 7/139 (5%)
Query: 318 QEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVL---VLRL 374
+ +L+ LE+++ QL EE + L E L E E + + EL E+L RL
Sbjct: 879 ENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARL 938
Query: 375 ENYE----RQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPG 430
E E + Q E ++ Q+L L+++ A +KLQ + + + +L++E +
Sbjct: 939 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD 998
Query: 431 FQETLAEELRTSLRRMISD 449
Q + R L ISD
Sbjct: 999 DQNNKLSKERKLLEERISD 1017
Score = 35.0 bits (79), Expect = 0.20
Identities = 56/257 (21%), Positives = 109/257 (42%), Gaps = 23/257 (8%)
Query: 199 QRERDLNTA-ARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYS 257
++E +L A AR+ + ++N+ L ++ +LE + +E++ R N ++ +
Sbjct: 1094 KKEEELQAALARLDDEIAQKNNAL-KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLG 1152
Query: 258 DSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEAL 317
+ E + E E+ + A +++ + E+++ + S EA + + +A+
Sbjct: 1153 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1212
Query: 318 QEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENY 377
+E LE+ TLE E L E + +A Q++ + L +++
Sbjct: 1213 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGE-LRVLGQAKQEVEHKKKKLEAQVQEL 1271
Query: 378 ERQ----QQEVARLQAQVLKLQQRCR-MYGAETE------KLQKQLASEKEIQMQLQEEE 426
+ + ++ A L +V KLQ + G E KL K +AS + QLQ+
Sbjct: 1272 QSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVAS---LSSQLQDT- 1327
Query: 427 TLPGFQETLAEELRTSL 443
QE L EE R L
Sbjct: 1328 -----QELLQEETRQKL 1339
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 58.5 bits (140), Expect = 2e-08
Identities = 90/419 (21%), Positives = 184/419 (43%), Gaps = 60/419 (14%)
Query: 199 QRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSD 258
Q+ L + Q ++ + L E ++ L + K+E+ + H++ R E
Sbjct: 880 QKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLE------- 932
Query: 259 SDEEDEDEE-EEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEAL 317
+EED ++ + E +K A++ + EE E+ + A + ++ EA +++ L
Sbjct: 933 -EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA--------KIKKL 983
Query: 318 QEKLRLLEEENHQLREEASQLD--------TLEDEEQMLILECVEQFSEASQQMAELSEV 369
++++ +++++N++L +E L+ L +EE E + ++ + +
Sbjct: 984 EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE-----EKAKNLTKLKNKHESMISE 1038
Query: 370 LVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLP 429
L +RL+ E+ +QE+ +L+ KL+ + + LQ Q+A E++MQL ++E
Sbjct: 1039 LEVRLKKEEKSRQELEKLKR---KLEGDASDFHEQIADLQAQIA---ELKMQLAKKE--- 1089
Query: 430 GFQETLAEELRTSLRRM---ISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEA 486
EEL+ +L R+ I+ +++ E+ G S L+ D SE + + +
Sbjct: 1090 -------EELQAALARLDDEIAQKNNALKKIREL-EGHISDLQEDLD-SERAARNKAEKQ 1140
Query: 487 EEGLMLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGWEE--VE 544
+ L + ++ E + Q+EL A + E+ V + + EET E E
Sbjct: 1141 KRDLGEELEALKTELEDTLDSTATQQELRAKR----EQEVTVLKKALDEETRSHEAQVQE 1196
Query: 545 LELDEATRMNVVTSALEASGLGPSHLDMNYVLQQLANWQDAHYRRQLRWKMLQKGECPH 603
+ A + +T LE ++LD N +Q ++A +LR K E H
Sbjct: 1197 MRQKHAQAVEELTEQLEQFKRAKANLDKN---KQTLEKENADLAGELRVLGQAKQEVEH 1252
Score = 55.1 bits (131), Expect = 2e-07
Identities = 98/410 (23%), Positives = 167/410 (40%), Gaps = 57/410 (13%)
Query: 209 RIGQSLVKQNSVLMEENSKLEA---LLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDED 265
R +L K L +EN+ L +LG AK+E+ + + ++ + + LQ S D +
Sbjct: 1217 RAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ----SKCSDGE 1272
Query: 266 EEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLE 325
E + + Q E E+ + A KL A L LQ+ LL+
Sbjct: 1273 RARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ-------LQDTQELLQ 1325
Query: 326 EENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEVA 385
EE Q +++L LE+E L + +++ EA Q + L ++L + +++ Q+ A
Sbjct: 1326 EETRQKLNVSTKLRQLEEERNSL-QDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFA 1384
Query: 386 -----------RLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPGFQET 434
R Q ++ L Q+ A +KL+K ++ +Q +L + Q
Sbjct: 1385 STVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK---TKNRLQQELDDLVVDLDNQRQ 1441
Query: 435 LAEELRTSLRRMISDPVYFMERNY------EMPRGDTSSLRYDFR-YSEDREQVRGFEAE 487
L L R+ D + E+N E R + + + + S R EA+
Sbjct: 1442 LVSNLEKKQRKF--DQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAK 1499
Query: 488 EGL-----MLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGWEE 542
E L ML A++ ED +++ V + K A E MEE + EE E +E
Sbjct: 1500 EELERTNKMLKAEM---EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE--DE 1554
Query: 543 VELELDEATRMNVVTSALEASGLGPSHLDMNYVLQQLANWQDAHYRRQLR 592
++ D R+ V AL+ G D+ Q + Q+ RRQL+
Sbjct: 1555 LQATEDAKLRLEVNMQALK----GQFERDL-----QARDEQNEEKRRQLQ 1595
Score = 48.5 bits (114), Expect = 2e-05
Identities = 48/206 (23%), Positives = 92/206 (44%), Gaps = 16/206 (7%)
Query: 252 LLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHC 311
LLQ+ +E E+E ++ KE +++ E E E + + + + L+ ++
Sbjct: 844 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 903
Query: 312 PQLEALQEKLRLLEEENHQ-LREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVL 370
+ E ++ +L ++E + L E ++L+ ED Q L E + +QQM +L E L
Sbjct: 904 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAE----RKKMAQQMLDLEEQL 959
Query: 371 VLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQ--LASEK--EIQMQLQEEE 426
++ Q E +A++ KL+ + + KL K+ L E+ ++ L EEE
Sbjct: 960 EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE 1019
Query: 427 -------TLPGFQETLAEELRTSLRR 445
L E++ EL L++
Sbjct: 1020 EKAKNLTKLKNKHESMISELEVRLKK 1045
Score = 45.8 bits (107), Expect = 1e-04
Identities = 87/409 (21%), Positives = 163/409 (39%), Gaps = 62/409 (15%)
Query: 214 LVKQNSVLMEENSKLEALLGSAKEEI-----LYLRHQVNLRDELLQLYSDSDEEDEDEEE 268
L K L + +++ L ++E+ LR +VN++ Q D DE EE
Sbjct: 1530 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1589
Query: 269 EEEEKEAEEEQEEEEAEEDLQCAHPCDAPK-----------LISQEALL-HQHHCPQLEA 316
+ + + + + E E E++ + A K L + A+ + QL
Sbjct: 1590 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1649
Query: 317 LQEKLRLLEEE----------------NHQLREEASQLDTLEDEEQMLILECVEQFSEAS 360
LQ +++ + E ++ + ++ + D ++ +E + E + +A
Sbjct: 1650 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK--QAD 1707
Query: 361 QQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQ--------------RCRMYGAETE 406
+ EL+E L L Q E RL+A++ +L++ R R + E
Sbjct: 1708 LEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAE 1767
Query: 407 KLQKQLASEKEIQMQLQEEETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTS 466
+L +LA+E+ Q+ E+ E +ELR+ L M + +
Sbjct: 1768 QLSNELATERS---TAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIA 1824
Query: 467 SLRYDFRYSEDREQVRGFEA--EEGLMLAADIMRGEDFTP-AEEFVPQEELGAAKKVPAE 523
L E RE+ ++ ++ L +++ ED AE++ Q E G A +V
Sbjct: 1825 QLEEQVE-QEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNA-RVKQL 1882
Query: 524 EGVMEEAELVSEE-TEGWEEVELELDEATRMNVV----TSALEASGLGP 567
+ +EEAE S+ +++ ELDEAT N +AL++ GP
Sbjct: 1883 KRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRGP 1931
Score = 44.3 bits (103), Expect = 3e-04
Identities = 63/262 (24%), Positives = 115/262 (43%), Gaps = 28/262 (10%)
Query: 150 FIRELEEALCPNLPPPVKKITQEDVKVMLYLLEELLPPVWESVTYGMVLQRERDLNT--- 206
F RELE+A + +E+ K L +L+ + E + +++ DL
Sbjct: 1657 FQRELEDARASR--DEIFATAKENEKKAKSLEADLMQ-LQEDLAAAERARKQADLEKEEL 1713
Query: 207 AARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDE----- 261
A + SL +N+ L +E +LEA + +EE L +E + + SD
Sbjct: 1714 AEELASSLSGRNA-LQDEKRRLEARIAQLEEE---------LEEEQGNMEAMSDRVRKAT 1763
Query: 262 EDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKL 321
+ ++ E E Q+ E A + L+ + KL E + + AL+ K+
Sbjct: 1764 QQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKI 1823
Query: 322 RLLEEE-NHQLREEASQLDTLEDEEQML--ILECVEQFSEASQQMAELSEVLVLRLENYE 378
LEE+ + RE+ + +L+ +++ L IL VE + ++Q E +E R++ +
Sbjct: 1824 AQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLK 1883
Query: 379 RQ----QQEVARLQAQVLKLQQ 396
RQ ++E R+ A KLQ+
Sbjct: 1884 RQLEEAEEESQRINANRRKLQR 1905
Score = 40.0 bits (92), Expect = 0.006
Identities = 37/139 (26%), Positives = 63/139 (45%), Gaps = 7/139 (5%)
Query: 318 QEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVL---VLRL 374
+ +L+ LE+++ QL EE + L E L E E + + EL E+L RL
Sbjct: 872 ENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARL 931
Query: 375 ENYE----RQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPG 430
E E + Q E ++ Q+L L+++ A +KLQ + + + +L++E +
Sbjct: 932 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD 991
Query: 431 FQETLAEELRTSLRRMISD 449
Q + R L ISD
Sbjct: 992 DQNNKLSKERKLLEERISD 1010
Score = 35.0 bits (79), Expect = 0.20
Identities = 56/257 (21%), Positives = 109/257 (42%), Gaps = 23/257 (8%)
Query: 199 QRERDLNTA-ARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYS 257
++E +L A AR+ + ++N+ L ++ +LE + +E++ R N ++ +
Sbjct: 1087 KKEEELQAALARLDDEIAQKNNAL-KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLG 1145
Query: 258 DSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEAL 317
+ E + E E+ + A +++ + E+++ + S EA + + +A+
Sbjct: 1146 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1205
Query: 318 QEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENY 377
+E LE+ TLE E L E + +A Q++ + L +++
Sbjct: 1206 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGE-LRVLGQAKQEVEHKKKKLEAQVQEL 1264
Query: 378 ERQ----QQEVARLQAQVLKLQQRCR-MYGAETE------KLQKQLASEKEIQMQLQEEE 426
+ + ++ A L +V KLQ + G E KL K +AS + QLQ+
Sbjct: 1265 QSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVAS---LSSQLQDT- 1320
Query: 427 TLPGFQETLAEELRTSL 443
QE L EE R L
Sbjct: 1321 -----QELLQEETRQKL 1332
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 57.4 bits (137), Expect = 4e-08
Identities = 35/98 (35%), Positives = 57/98 (58%), Gaps = 7/98 (7%)
Query: 248 LRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLH 307
L ++L + +S +E+E+EEEEEEE+E EEE+EEE+ EE+ + D + +E
Sbjct: 874 LEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEE-----DEEEYFEEEEEEE 928
Query: 308 QHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEE 345
+ + E +E+ L EEE + EE +L+ +ED E
Sbjct: 929 EEFEEEFE--EEEGELEEEEEEEDEEEEEELEEVEDLE 964
Score = 38.1 bits (87), Expect = 0.024
Identities = 20/63 (31%), Positives = 34/63 (53%)
Query: 223 EENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEE 282
EE + E ++E Y + +E + + + + E E+EEEEE+E+E EE +E E
Sbjct: 902 EEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVE 961
Query: 283 EAE 285
+ E
Sbjct: 962 DLE 964
Score = 37.0 bits (84), Expect = 0.054
Identities = 22/65 (33%), Positives = 34/65 (52%)
Query: 223 EENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEE 282
EE + E +EE + +E + + +EE E+E EEEE + EEE+EE+
Sbjct: 891 EEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEED 950
Query: 283 EAEED 287
E EE+
Sbjct: 951 EEEEE 955
Score = 30.8 bits (68), Expect = 3.9
Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 7/94 (7%)
Query: 275 AEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKL-RLLEEENHQLRE 333
+ +E+EEEE EE+ + + + +E + + + E +E+ EEE +L E
Sbjct: 885 SSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEE 944
Query: 334 EASQLDTLEDEEQMLILECVE--QFSEASQQMAE 365
E + D E+EE LE VE +F A ++ E
Sbjct: 945 EEEEEDEEEEEE----LEEVEDLEFGTAGGEVEE 974
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 57.4 bits (137), Expect = 4e-08
Identities = 70/283 (24%), Positives = 120/283 (42%), Gaps = 39/283 (13%)
Query: 200 RERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEE----ILYLRHQVNLRDELLQL 255
R+++ + R+ ++L KQ L E S+++ + EE LR + +L
Sbjct: 282 RDKNESLTMRLHETL-KQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDA 340
Query: 256 YSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDA---PKLISQEALLHQHH-- 310
++ EE +E EK+A+ E+E A +D +C + KL E L Q
Sbjct: 341 LNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDN 400
Query: 311 -----------CPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEA 359
QLE L+++ L N QL+ L+T +++ +L F E
Sbjct: 401 PPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEE 460
Query: 360 SQQMAELSEVLVLRLENYERQQQEV--------ARLQAQVLKLQQRCRMYGAETEKLQKQ 411
QQ++ L L + N + ++E+ ARL AQV L A ++ ++
Sbjct: 461 KQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQE 520
Query: 412 LA----SEKEIQMQL-----QEEETLPGFQETLAEELRTSLRR 445
LA KE Q QL Q+E+ G + + E+L +SL++
Sbjct: 521 LAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQV-EQLSSSLKQ 562
Score = 52.4 bits (124), Expect = 1e-06
Identities = 55/247 (22%), Positives = 112/247 (45%), Gaps = 38/247 (15%)
Query: 209 RIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEE- 267
R Q L + + E+ S L+ G EE L + NL + L++ D E +E
Sbjct: 1421 RTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQEL 1480
Query: 268 ----EEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRL 323
+ E + AE ++E + +L E + ++ +++ L+E+ R
Sbjct: 1481 AAVRADAETRLAEVQREAQSTAREL--------------EVMTAKYEGAKVKVLEERQRF 1526
Query: 324 LEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQE 383
+EE +L + QL+ + E+ ++Q+ ELS+ L + + QQQ+
Sbjct: 1527 -QEERQKLTAQVEQLEVFQREQ--------------TKQVEELSKKLADSDQASKVQQQK 1571
Query: 384 VARLQAQVLKLQQRCRMYGAETEKLQKQLASEKE----IQMQLQEEETLPGFQETLAEEL 439
+ +QAQ + QQ + A+ +LQ QL+ +++ ++Q+++ +T ++ +EL
Sbjct: 1572 LKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQEL 1631
Query: 440 RTSLRRM 446
+ LR +
Sbjct: 1632 QEQLRSL 1638
Score = 47.8 bits (112), Expect = 3e-05
Identities = 47/205 (22%), Positives = 94/205 (45%), Gaps = 11/205 (5%)
Query: 200 RERDLNTAARIGQSL--VKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYS 257
RE ++ TA G + +++ EE KL A + + ++ R Q +EL + +
Sbjct: 1503 RELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLE---VFQREQTKQVEELSKKLA 1559
Query: 258 DSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEAL 317
DSD+ + ++++ + +A+ + ++EA+ LQ A + +SQ+ +H+ Q+E
Sbjct: 1560 DSDQASKVQQQKLKAVQAQGGESQQEAQR-LQ-AQLNELQAQLSQKEQAAEHYKLQMEKA 1617
Query: 318 QEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENY 377
+ +++N +L+E+ L+ L+ E + L E E Q + E +
Sbjct: 1618 KTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEA----EQTC 1673
Query: 378 ERQQQEVARLQAQVLKLQQRCRMYG 402
+V L+AQV Q+ R G
Sbjct: 1674 RHLTAQVRSLEAQVAHADQQLRDLG 1698
Score = 45.8 bits (107), Expect = 1e-04
Identities = 62/278 (22%), Positives = 126/278 (45%), Gaps = 12/278 (4%)
Query: 267 EEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLEE 326
+E EE ++ ++ +E+ A+++ + A A S+ A + P+LEAL+ ++ LE+
Sbjct: 1078 KELEELRQTVKQLKEQLAKKEKEHASGSGAQ---SEAAGRTEPTGPKLEALRAEVSKLEQ 1134
Query: 327 ENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEVAR 386
+ + +E+A L+ + E+ E Q+ E ++ L Q+E+A
Sbjct: 1135 QCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAA 1194
Query: 387 LQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPGFQETLAEELRTSLRRM 446
+ +V + + A+ + +++ + + L+EE ++ Q E L+R+
Sbjct: 1195 FRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRL 1254
Query: 447 I---SDPVYFMERNYEMPRGDT--SSLRYDFRYSEDREQVRGFEAE-EGLMLAADIMRGE 500
+ S+ +E + + +T +S R R S RE+V+ E E +A++ +R E
Sbjct: 1255 VMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQE 1314
Query: 501 DFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETE 538
+ AE EELG K E+ +E L + + E
Sbjct: 1315 LTSQAER---AEELGQELKAWQEKFFQKEQALSTLQLE 1349
Score = 45.8 bits (107), Expect = 1e-04
Identities = 75/371 (20%), Positives = 155/371 (41%), Gaps = 52/371 (14%)
Query: 199 QRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSD 258
Q ++ A + +SL + + E +S LE L G +E+ L H + + +
Sbjct: 1135 QCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAA 1194
Query: 259 SDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQ 318
+ +D + E+E +A+ + +EAE + I +L + E
Sbjct: 1195 FRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEK------EGES 1248
Query: 319 EKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYE 378
++L+ L + E+ + LE+ ++L E + A+++ + L E + E E
Sbjct: 1249 KELKRL------VMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAE 1302
Query: 379 RQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPGFQETLAEE 438
+Q+ L+ ++ +R G E + Q++ +++ LQ E
Sbjct: 1303 KQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLE------------- 1349
Query: 439 LRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAEEGLMLAADIMR 498
TS + ++S+ + + + + R+ E+ EQ + +A G L A+++R
Sbjct: 1350 -HTSTQALVSE---LLPAKHLCQQLQAEQAAAEKRHREELEQSK--QAAGG--LRAELLR 1401
Query: 499 GE----DFTPAEEFVPQEE-----LGAAKKVPAEE-GVMEEAE-LVSEETEGWEE----- 542
+ + P + V ++E L A K AE+ ++++A L++EE G E
Sbjct: 1402 AQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLG 1461
Query: 543 ---VELELDEA 550
+E+ELD+A
Sbjct: 1462 RQFLEVELDQA 1472
Score = 43.1 bits (100), Expect = 8e-04
Identities = 114/543 (20%), Positives = 212/543 (39%), Gaps = 99/543 (18%)
Query: 146 ERAAFIRELEEALCPNLPPPVKKITQEDVKVMLYLLEELLPPVWESVTYGMVLQRERDLN 205
E A+ +++L++AL ++T+E K LE+ Q E++L+
Sbjct: 329 EFASHLQQLQDAL--------NELTEEHSKATQEWLEKQA-------------QLEKELS 367
Query: 206 TAARIGQSLVKQNSVLMEENSKLEALLGSAKE-----------EILYL----RHQVNLRD 250
A + + L ++N +L + S+LE L ++ ++L L + L
Sbjct: 368 AALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAA 427
Query: 251 ELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEE------DLQCA--HPCDAPKLISQ 302
QL + + + + ++E + AE EEE ++ DLQ + + A + + Q
Sbjct: 428 NNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQ 487
Query: 303 EALLHQHHCP-QLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQ 361
+ H Q+ +L +L L Q +E + L E+Q + + ++Q +ASQ
Sbjct: 488 ASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQ 547
Query: 362 QMAELSEVLVLRLENYERQQQEVARLQ-------AQVL---------KLQQRCRMYGAET 405
+ E L L+ E+Q +EVA Q AQ L L++R +
Sbjct: 548 GLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAAL-KQL 606
Query: 406 EKLQKQLASEKEI-QMQLQ---EEETLPGFQETLAEELRTSLRRMISDPVYFME---RNY 458
E L+K+ A++ EI Q QLQ E T A+ + L R + + +E +
Sbjct: 607 EALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQ 666
Query: 459 EMPRGDTSSLRYDFR-------------YSEDREQVRGFEAEEGLMLAADIMRGEDFTPA 505
+ + L R +D+ Q + +E L + + E A
Sbjct: 667 HEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAA 726
Query: 506 EEFVPQE----ELGAAKKVPAEEGVMEEAELVSEET--EGWEEVELELDEATRMNVVTSA 559
+ Q+ EL A + E+ E EL E +G E +L EA +
Sbjct: 727 DALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLR 786
Query: 560 LE-ASGLGPSHL---DMNYVLQQLANWQDAHYRRQLRWKMLQKGECPHGALPAASRTSCR 615
E A + H + +++++A W++ R++ Q+ E +GA+ + +
Sbjct: 787 RELAEAMAAQHTAESECEQLVKEVAAWRE-------RYEDSQQEEAQYGAMFQEQLMTLK 839
Query: 616 SSC 618
C
Sbjct: 840 EEC 842
Score = 43.1 bits (100), Expect = 8e-04
Identities = 57/241 (23%), Positives = 105/241 (43%), Gaps = 39/241 (16%)
Query: 209 RIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDED--- 265
++G++ + VL E ++ A +A+ E L +V E Y DS +E+
Sbjct: 773 QLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRER---YEDSQQEEAQYGA 829
Query: 266 --EEE-----EEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQ 318
+E+ EE EK +E QE +E ++ + ++ A LH + L+ +Q
Sbjct: 830 MFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQ 889
Query: 319 EK----------LRLLEEENHQLREEASQLDTL----EDEEQMLILECVEQFSEASQQMA 364
EK L L+E+ +E ++L+TL ++++ E V++ + A +
Sbjct: 890 EKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQP 949
Query: 365 ELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQE 424
E E E+Q ++ QA + +++ G E E+L+ A+ E Q Q QE
Sbjct: 950 EWLE---------EQQGRQFCSTQAALQAMEREAEQMGNELERLR---AALMESQGQQQE 997
Query: 425 E 425
E
Sbjct: 998 E 998
Score = 36.2 bits (82), Expect = 0.092
Identities = 50/256 (19%), Positives = 103/256 (40%), Gaps = 47/256 (18%)
Query: 194 YGMVLQRERDLNTAARIGQSLVKQNSVLMEEN--SKLEALLGSAKEEILYLRHQVNLRDE 251
+G++ + R L A +G+ ++ E +L A+ A+ + ++ +
Sbjct: 1444 HGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTAR 1503
Query: 252 LLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHC 311
L++ + E + + EE ++ EE Q+ E L+ + +
Sbjct: 1504 ELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLE---------------VFQREQT 1548
Query: 312 PQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLV 371
Q+E L +KL ++ Q ++ ++ L+ V+ SQQ A
Sbjct: 1549 KQVEELSKKL-----------ADSDQASKVQQQK----LKAVQAQGGESQQEA------- 1586
Query: 372 LRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEE-ETLPG 430
+R Q ++ LQAQ+ + +Q Y + EK + ++K+ +LQE+ +L
Sbjct: 1587 ------QRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQ 1640
Query: 431 FQETLAEELRTSLRRM 446
Q+ +ELR R+
Sbjct: 1641 LQKE-NKELRAEAERL 1655
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 57.0 bits (136), Expect = 5e-08
Identities = 51/242 (21%), Positives = 119/242 (49%), Gaps = 18/242 (7%)
Query: 215 VKQNSVLMEENSKL---EALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEE 271
+++ E+ +K+ E + +E+I ++ ++E + EE++ +E+EE
Sbjct: 466 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEM 525
Query: 272 EKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLEE----E 327
++ E+ +E+EE + H + +E + Q ++ +EK+R EE +
Sbjct: 526 WRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEE--KMHDQEEKIREQEEKVWRQ 583
Query: 328 NHQLREEASQLDTLED---EEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEV 384
++RE+ ++ E+ E++ + E E+ E ++M E E + + E RQ++++
Sbjct: 584 EEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKI 643
Query: 385 ----ARLQAQVLKLQQRCRMYGAETEKL--QKQLASEKEIQMQLQEEETLPGFQETLAEE 438
+++ Q K++++ M + EK+ Q++ E+E +MQ QEE+ ++ +E
Sbjct: 644 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 703
Query: 439 LR 440
+R
Sbjct: 704 VR 705
Score = 47.8 bits (112), Expect = 3e-05
Identities = 44/195 (22%), Positives = 92/195 (47%), Gaps = 25/195 (12%)
Query: 212 QSLVKQNSVLMEENSKL---EALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEE 268
+ + +Q + E+ K+ E + +E++ ++ ++E + + E E++
Sbjct: 536 EEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIR 595
Query: 269 EEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQE---KLRLLE 325
E+EEK E+E+ +E EE K+ QE + C Q E +QE K+R E
Sbjct: 596 EQEEKIREQEEMTQEQEE-----------KMGEQEEKM----CEQEEKMQEQEEKMRRQE 640
Query: 326 EENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEV- 384
E+ + ++ + + E++ ++ E E+ E ++M E E + + E RQ++++
Sbjct: 641 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 700
Query: 385 ---ARLQAQVLKLQQ 396
RL+ Q K+Q+
Sbjct: 701 EQEVRLRQQEEKMQE 715
Score = 45.8 bits (107), Expect = 1e-04
Identities = 39/204 (19%), Positives = 93/204 (45%), Gaps = 15/204 (7%)
Query: 223 EENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEE 282
EE + + + KE+I ++ ++E + + + E++ E+EEK +E++
Sbjct: 529 EEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIR 588
Query: 283 EAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLE 342
E EE K+ QE + + Q E QE+ + E+ ++ E+ ++ E
Sbjct: 589 EQEE-----------KIREQEEKIRE----QEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 633
Query: 343 DEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYG 402
++ + + EQ + +Q ++ E + E E+ ++ ++ Q K+Q++
Sbjct: 634 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 693
Query: 403 AETEKLQKQLASEKEIQMQLQEEE 426
+ EK+ +Q ++ + ++QE +
Sbjct: 694 RQEEKMWEQEVRLRQQEEKMQEHQ 717
Score = 39.7 bits (91), Expect = 0.008
Identities = 77/372 (20%), Positives = 158/372 (42%), Gaps = 39/372 (10%)
Query: 198 LQRERDLNTAARIGQSLVKQNSVLMEENSKLEA---LLGSAKEEILYLRHQVNLRDELLQ 254
L +ERD + ++ + L E+N+KL+ L+ S K EI ++ + E +
Sbjct: 259 LTKERDALSLELYRNTITDEE--LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAK 316
Query: 255 LYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQL 314
L + + + +E ++ + + + EE+ +L ++ L+Q ++
Sbjct: 317 LLLPQQQLQAEADHLGKELQSVSAKLQAQVEEN----------ELWNR---LNQQQEEKM 363
Query: 315 EALQEKLR----LLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVL 370
+EK++ ++E+ ++RE+ ++ E EE+M E E E ++M E++
Sbjct: 364 WRQEEKIQEWEEKIQEQEEKIREQEEKI--REQEEKMRRQE--EMMWEKEEKMRRQEEMM 419
Query: 371 VLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEK-EIQMQLQEEETLP 429
+ E RQ++ + + ++ +L+++ E+ +K+ EK Q + QE+E
Sbjct: 420 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 479
Query: 430 GFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYD----FRYSED-REQVRGF 484
QE E +R E+ +E + R + +R E REQ +
Sbjct: 480 WRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIW 539
Query: 485 EAEEGLMLAADIMRGED---FTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGWE 541
+E + + +R ++ + E+ QEE K EE V + E + E+ E
Sbjct: 540 RQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEE----KIREQEEKVWRQEEKIREQEEKIR 595
Query: 542 EVELELDEATRM 553
E E ++ E M
Sbjct: 596 EQEEKIREQEEM 607
Score = 31.6 bits (70), Expect = 2.3
Identities = 25/107 (23%), Positives = 49/107 (45%), Gaps = 6/107 (5%)
Query: 212 QSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEE 271
+ + +Q + E+ K+ +E+ +R Q +E ++ + +E E++ E+E
Sbjct: 620 EKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQ----EEKIREQEEMMQEQEEKMWEQE 675
Query: 272 EK--EAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEA 316
EK E EE+ +E+E + Q + + Q+ Q H LEA
Sbjct: 676 EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 722
Score = 30.8 bits (68), Expect = 3.9
Identities = 39/164 (23%), Positives = 76/164 (46%), Gaps = 18/164 (10%)
Query: 167 KKITQEDVKVMLYLLEELLPPVWESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENS 226
+KI +++ KV + EE + E + RE++ T + + + +Q + E+
Sbjct: 571 EKIREQEEKV--WRQEEKIREQEEKIREQEEKIREQEEMTQEQ-EEKMGEQEEKMCEQEE 627
Query: 227 KLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEE--EEEEEKEAEEEQ---EE 281
K++ ++E R + +R++ ++ ++ E EE +E+EEK E+E+ E+
Sbjct: 628 KMQ------EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQ 681
Query: 282 EEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLE 325
EE ++ + K+ QE L Q Q E +QE LE
Sbjct: 682 EEKMQEQEEKMRRQEEKMWEQEVRLRQ----QEEKMQEHQEHLE 721
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 57.0 bits (136), Expect = 5e-08
Identities = 60/255 (23%), Positives = 118/255 (46%), Gaps = 40/255 (15%)
Query: 208 ARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEE 267
+++ SL S +EN K +A + ++ L+HQ+ +Q+ + E+ E ++
Sbjct: 863 SKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQ-----VQMENTLKEQKELKK 917
Query: 268 EEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLEEE 327
E+EKEA + + E Q LI + L Q+ + + LQ + L++
Sbjct: 918 SLEKEKEASHQLKLELNSMQEQ---------LIQAQNTLKQNE-KEEQQLQGNINELKQS 967
Query: 328 NHQLREEASQLDTLEDEEQMLILECVE-------QFSEASQQMAELSEVLVLRLENYERQ 380
+ Q ++ Q++ L+ E ++ +L+ E Q ++A+Q++A E + + NYE+
Sbjct: 968 SEQKKK---QIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKS 1024
Query: 381 QQEVARLQAQVLKLQQRCRMYGAETEKL-QKQLASEKEIQMQLQEEETLP-----GFQET 434
Q+ +LQ+ YG E+E L +Q E ++ L +E+ + G Q
Sbjct: 1025 QETFKQLQSD---------FYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNK 1075
Query: 435 LAEELRTSLRRMISD 449
L +EL+T+ + D
Sbjct: 1076 LIQELKTAKATLEQD 1090
Score = 50.8 bits (120), Expect = 4e-06
Identities = 58/269 (21%), Positives = 126/269 (46%), Gaps = 33/269 (12%)
Query: 223 EENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEE 282
++ +E L A+E+++ R+Q+ +++L+Q + + E++ K+ ++ QE
Sbjct: 1047 QDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTA----KATLEQDSAKKEQQLQERC 1102
Query: 283 EAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEK--LRLLEEENHQLREEASQLDT 340
+A +D+Q +L+++++ L + +++ QEK +L EE E ++
Sbjct: 1103 KALQDIQKEKSLKEKELVNEKSKLAE--IEEIKCRQEKEITKLNEELKSHKLESIKEITN 1160
Query: 341 LEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRM 400
L+D +Q+LI + +E +A A + + E++ Q++ L+ QV K ++ +
Sbjct: 1161 LKDAKQLLIQQKLELQGKADSLKAAVEQ---------EKRNQQI--LKDQVKKEEEELKK 1209
Query: 401 YGAETEKLQKQLASEKEIQMQLQEEE------TLPGFQE---TLAEELRTSLRRMISDPV 451
E E EKE+ M+ EE + E T+ +E ++S RR V
Sbjct: 1210 EFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRR-----V 1264
Query: 452 YFMERNYEMPRGDTSSLRYDFRYSEDREQ 480
+E+ + RG+ + L + ++D +
Sbjct: 1265 SELEKQTDDLRGEIAVLEATVQNNQDERR 1293
Score = 48.5 bits (114), Expect = 2e-05
Identities = 80/346 (23%), Positives = 150/346 (43%), Gaps = 51/346 (14%)
Query: 223 EENSKLEALLGSAKEEILYLRHQVN-LRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEE 281
E S+LE+ L KE+ L L + L ++ +L +DS E +E+ ++ + + +
Sbjct: 702 EHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNT 761
Query: 282 EEAEEDLQCAHPCDAPK-LISQEALLHQHHCPQLEALQEKLRLLEEENHQLR---EEASQ 337
+ + + + K ++S L Q LE++++KL EEE L+ E SQ
Sbjct: 762 DLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQ 821
Query: 338 LDTLEDEE-----QMLILECVEQFSEASQQMAELSEV------LVLRLENYERQ-QQEVA 385
++ EE Q + E + E M ELS V + L+N + + ++E
Sbjct: 822 ETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQ 881
Query: 386 RLQAQVLKLQQRCRMYG-----------AETEKLQKQLASEKEIQMQLQEEETLPGFQET 434
+ +A +L L++ C+ E ++L+K L EKE QL+ E L QE
Sbjct: 882 KGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLE--LNSMQEQ 939
Query: 435 LAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAEEGLMLAA 494
L + T + E+ + +G+ + L+ ++ + EA +G + A
Sbjct: 940 LIQAQNTLKQN---------EKEEQQLQGNINELK-----QSSEQKKKQIEALQGELKIA 985
Query: 495 DIMRGEDFTPAEEFVPQEELGAAKKVPAEE---GVMEEAELVSEET 537
+ + T E + Q+ AA+++ AE+ V++ S+ET
Sbjct: 986 VLQK----TELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQET 1027
Score = 43.9 bits (102), Expect = 4e-04
Identities = 62/296 (20%), Positives = 123/296 (41%), Gaps = 32/296 (10%)
Query: 161 NLPPPVKKITQEDVKVMLYLLEELLPPVWESVTYGMVLQRER-DLNTAARIGQS------ 213
+L +++I +D K+ LE LL E+++ +L++ER DL + G+
Sbjct: 510 DLEQVLRQIGDKDQKIQN--LEALLQKSKENIS---LLEKEREDLYAKIQAGEGETAVLN 564
Query: 214 -LVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQ----LYSDSDEEDEDEEE 268
L ++N L E+ ++L L + E + + Q NL D++ + L + D E
Sbjct: 565 QLQEKNHTLQEQVTQLTEKLKNQSES--HKQAQENLHDQVQEQKAHLRAAQDRVLSLETS 622
Query: 269 EEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLEEEN 328
E E +E+ ++ D+Q + L+S EA L L+++
Sbjct: 623 VNELNSQLNESKEKVSQLDIQIKAKTEL--LLSAEAAKTAQRADLQNHLDTAQNALQDKQ 680
Query: 329 HQLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQ 388
+L + +QLD + + + + ++L L E Y +Q+ L+
Sbjct: 681 QELNKITTQLD-----------QVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELE 729
Query: 389 AQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPGFQETLAEELRTSLR 444
Q+ KL+ A E+ + L ++++ L+ T Q + +E+ +S R
Sbjct: 730 GQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTR 785
Score = 41.6 bits (96), Expect = 0.002
Identities = 70/297 (23%), Positives = 123/297 (41%), Gaps = 27/297 (9%)
Query: 180 LLEELLPPVWESVTYGMVLQR-ERDLNTAARIGQSLVKQNSVLMEENSKLEALLGS---A 235
L EL E Y LQ+ + +N + Q+L + ++ +KLE +
Sbjct: 272 LRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVS 331
Query: 236 KEEILYLRHQVNLRDELLQLYSDSDEED--EDEEEEEEEKEAEEEQEEEEAEEDLQCAHP 293
K+ I HQ +L + LQ + E E E+ EA ++ +EE +E + + H
Sbjct: 332 KKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHL 391
Query: 294 CDAPKLISQEALLHQHHCPQLEALQEKL--RLLEEEN-----HQLREEASQLDT--LEDE 344
K + Q+ + H QL++ +L +LLE E H +E QL + L D+
Sbjct: 392 KAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDK 451
Query: 345 EQML------ILECVEQFSEASQQMAELSEVLVLRLENYERQQ----QEVARLQAQVLKL 394
EQ + + EQ E EL L + ++ QQ A+L+ L
Sbjct: 452 EQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDL 511
Query: 395 QQRCRMYGAETEKLQ--KQLASEKEIQMQLQEEETLPGFQETLAEELRTSLRRMISD 449
+Q R G + +K+Q + L + + + L E+E + + A E T++ + +
Sbjct: 512 EQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQE 568
>gi|217272804 hyaluronan-mediated motility receptor isoform d [Homo
sapiens]
Length = 638
Score = 56.2 bits (134), Expect = 9e-08
Identities = 72/318 (22%), Positives = 123/318 (38%), Gaps = 63/318 (19%)
Query: 221 LMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQE 280
L E+N ++ +L S +E I+ L QV + QL E+ + E E E Q
Sbjct: 175 LKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQN 234
Query: 281 -------EEEAEEDLQCAHPCDAPKLISQE----ALLHQHHCPQLEALQEKLRLLEEENH 329
E++ E LQ L+ QE + LHQ C E + ++ L EEE
Sbjct: 235 LKQKFILEQQEREKLQ-QKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELK 293
Query: 330 QLREEASQLDTLEDEEQMLILECVEQFSEASQQMAELSEVL------------------V 371
Q +E +L E++ + L+ + E+ ++++ L E L +
Sbjct: 294 QTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQATL 353
Query: 372 LRLENYERQQQ------------------EVARLQAQVLKLQQRCRMYGAETEKLQKQL- 412
L E Y+ Q E+ L+ + LQ++ G E +Q Q+
Sbjct: 354 LLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAGKNAEDVQHQIL 413
Query: 413 ---ASEKEIQMQLQEEETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLR 469
+S +E L + +T +ET +E+ S + I+D +++ E
Sbjct: 414 ATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQLKQQEE---------- 463
Query: 470 YDFRYSEDREQVRGFEAE 487
DFR + E+ R E E
Sbjct: 464 -DFRKQLEDEEGRKAEKE 480
Score = 42.4 bits (98), Expect = 0.001
Identities = 50/209 (23%), Positives = 93/209 (44%), Gaps = 16/209 (7%)
Query: 224 ENSKLEALLGSAKEEILYLRHQV----NLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQ 279
ENS L+ A + ++HQ+ + E +++ D + +E E +E Q
Sbjct: 390 ENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQ 449
Query: 280 EEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQE--KLRLLEEENHQLREEAS- 336
+ + + L+ +L +E + E +E K RLL EE + +
Sbjct: 450 KITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPFQL 509
Query: 337 QLDTLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQ 396
QLD E E+Q L+ E A +Q+ ++ + +L ++ +Q++ V+KL+
Sbjct: 510 QLDAFEVEKQALLNE----HGAAQEQLNKIRDSYA-KLLGHQNLKQKIKH----VVKLKD 560
Query: 397 RCRMYGAETEKLQKQLASEKEIQMQLQEE 425
+E KL+ QLA +K+ + +LQEE
Sbjct: 561 ENSQLKSEVSKLRCQLAKKKQSETKLQEE 589
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.129 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,637,745
Number of Sequences: 37866
Number of extensions: 1423031
Number of successful extensions: 49628
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 865
Number of HSP's successfully gapped in prelim test: 1170
Number of HSP's that attempted gapping in prelim test: 17541
Number of HSP's gapped (non-prelim): 13635
length of query: 619
length of database: 18,247,518
effective HSP length: 108
effective length of query: 511
effective length of database: 14,157,990
effective search space: 7234732890
effective search space used: 7234732890
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.