Search of human proteins with 24797143

Search of human proteins with 24797143

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24797143 sorting nexin 14 isoform b [Homo sapiens]
         (893 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24797143 sorting nexin 14 isoform b [Homo sapiens]                1795   0.0  
gi|24797145 sorting nexin 14 isoform a [Homo sapiens]                1766   0.0  
gi|38708169 sorting nexin 25 [Homo sapiens]                            68   4e-11
gi|17864088 sorting nexin 13 [Homo sapiens]                            56   1e-07
gi|157502171 sorting nexin 19 [Homo sapiens]                           55   3e-07
gi|31563383 serum/glucocorticoid regulated kinase 3 isoform 2 [H...    54   5e-07
gi|31563382 serum/glucocorticoid regulated kinase 3 isoform 1 [H...    54   5e-07
gi|75813626 serum/glucocorticoid regulated kinase 3 isoform 1 [H...    54   5e-07
gi|31543452 PX domain containing serine/threonine kinase [Homo s...    52   3e-06
gi|7706706 sorting nexin 9 [Homo sapiens]                              50   7e-06
gi|23238244 sorting nexin 16 isoform a [Homo sapiens]                  48   5e-05
gi|23238246 sorting nexin 16 isoform a [Homo sapiens]                  48   5e-05
gi|154091028 sorting nexin 29 [Homo sapiens]                           47   8e-05
gi|23943858 sorting nexin 8 [Homo sapiens]                             45   4e-04
gi|23111055 sorting nexin 7 isoform b [Homo sapiens]                   44   5e-04
gi|194294540 sorting nexin 7 isoform a [Homo sapiens]                  44   5e-04
gi|23111038 sorting nexin 2 [Homo sapiens]                             43   0.001
gi|27501450 axin 1 isoform a [Homo sapiens]                            42   0.003
gi|31083144 axin 1 isoform b [Homo sapiens]                            42   0.003
gi|23111026 sorting nexin 11 [Homo sapiens]                            42   0.003
gi|23111028 sorting nexin 11 [Homo sapiens]                            42   0.003
gi|153791707 sorting nexin family member 30 [Homo sapiens]             40   0.007
gi|66472382 nischarin [Homo sapiens]                                   40   0.013
gi|23111036 sorting nexin 1 isoform c [Homo sapiens]                   39   0.016
gi|23111034 sorting nexin 1 isoform a [Homo sapiens]                   39   0.016
gi|23111032 sorting nexin 1 isoform b [Homo sapiens]                   39   0.022
gi|21493033 A-kinase anchor protein 10 precursor [Homo sapiens]        38   0.037
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]         36   0.18 
gi|4506517 regulator of G-protein signaling 2, 24kDa [Homo sapiens]    35   0.24 
gi|224177511 sorting nexin 18 isoform c [Homo sapiens]                 35   0.31 

>gi|24797143 sorting nexin 14 isoform b [Homo sapiens]
          Length = 893

 Score = 1795 bits (4650), Expect = 0.0
 Identities = 893/893 (100%), Positives = 893/893 (100%)

Query: 1   MVPWVRTMGQKLKQRLRLDVGREICRQYPLFCFLLLCLSAASLLLNRYIHILMIFWSFVA 60
           MVPWVRTMGQKLKQRLRLDVGREICRQYPLFCFLLLCLSAASLLLNRYIHILMIFWSFVA
Sbjct: 1   MVPWVRTMGQKLKQRLRLDVGREICRQYPLFCFLLLCLSAASLLLNRYIHILMIFWSFVA 60

Query: 61  GVVTFYCSLGPDSLLPNIFFTIKYKPKQLGLQELFPQGHSCAVCGKVKCKRHRPSLLLEN 120
           GVVTFYCSLGPDSLLPNIFFTIKYKPKQLGLQELFPQGHSCAVCGKVKCKRHRPSLLLEN
Sbjct: 61  GVVTFYCSLGPDSLLPNIFFTIKYKPKQLGLQELFPQGHSCAVCGKVKCKRHRPSLLLEN 120

Query: 121 YQPWLDLKISSKVDASLSEVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEFLQQAALE 180
           YQPWLDLKISSKVDASLSEVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEFLQQAALE
Sbjct: 121 YQPWLDLKISSKVDASLSEVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEFLQQAALE 180

Query: 181 EYGPELHVALRSRRDELHYLRKLTELLFPYILPPKATDCRSLTLLIREILSGSVFLPSLD 240
           EYGPELHVALRSRRDELHYLRKLTELLFPYILPPKATDCRSLTLLIREILSGSVFLPSLD
Sbjct: 181 EYGPELHVALRSRRDELHYLRKLTELLFPYILPPKATDCRSLTLLIREILSGSVFLPSLD 240

Query: 241 FLADPDTVNHLLIIFIDDSPPEKATEPASPLVPFLQKFAEPRNKKPSVLKLELKQIREQQ 300
           FLADPDTVNHLLIIFIDDSPPEKATEPASPLVPFLQKFAEPRNKKPSVLKLELKQIREQQ
Sbjct: 241 FLADPDTVNHLLIIFIDDSPPEKATEPASPLVPFLQKFAEPRNKKPSVLKLELKQIREQQ 300

Query: 301 DLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDE 360
           DLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDE
Sbjct: 301 DLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDE 360

Query: 361 SIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEY 420
           SIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEY
Sbjct: 361 SIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEY 420

Query: 421 FRQLLRGAESPTRNSKLNRNTQKRGESFGISRIGSKIKGVFKSTTMEGAMLPNYGVAEGE 480
           FRQLLRGAESPTRNSKLNRNTQKRGESFGISRIGSKIKGVFKSTTMEGAMLPNYGVAEGE
Sbjct: 421 FRQLLRGAESPTRNSKLNRNTQKRGESFGISRIGSKIKGVFKSTTMEGAMLPNYGVAEGE 480

Query: 481 DDFIEEGIVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKERIPVFC 540
           DDFIEEGIVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKERIPVFC
Sbjct: 481 DDFIEEGIVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKERIPVFC 540

Query: 541 IDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFL 600
           IDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFL
Sbjct: 541 IDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFL 600

Query: 601 KSKREEFQEYLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKL 660
           KSKREEFQEYLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKL
Sbjct: 601 KSKREEFQEYLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKL 660

Query: 661 MKEKGQHLEPFIMNFINSCESPKPKPSRPELTILSPTSENNKKLFNDLFKNNANRAENTE 720
           MKEKGQHLEPFIMNFINSCESPKPKPSRPELTILSPTSENNKKLFNDLFKNNANRAENTE
Sbjct: 661 MKEKGQHLEPFIMNFINSCESPKPKPSRPELTILSPTSENNKKLFNDLFKNNANRAENTE 720

Query: 721 RKQNQNYFMEVMTVEGVYDYLMYVGRVVFQVPDWLHHLLMGTRILFKNTLEMYTDYYLQC 780
           RKQNQNYFMEVMTVEGVYDYLMYVGRVVFQVPDWLHHLLMGTRILFKNTLEMYTDYYLQC
Sbjct: 721 RKQNQNYFMEVMTVEGVYDYLMYVGRVVFQVPDWLHHLLMGTRILFKNTLEMYTDYYLQC 780

Query: 781 KLEQLFQEHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLLVKCIGE 840
           KLEQLFQEHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLLVKCIGE
Sbjct: 781 KLEQLFQEHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLLVKCIGE 840

Query: 841 ETKYESIRLLFDGLQQPVLNKQLTYVLLDIVIQELFPELNKVQKEVTSVTSWM 893
           ETKYESIRLLFDGLQQPVLNKQLTYVLLDIVIQELFPELNKVQKEVTSVTSWM
Sbjct: 841 ETKYESIRLLFDGLQQPVLNKQLTYVLLDIVIQELFPELNKVQKEVTSVTSWM 893


>gi|24797145 sorting nexin 14 isoform a [Homo sapiens]
          Length = 946

 Score = 1766 bits (4575), Expect = 0.0
 Identities = 893/946 (94%), Positives = 893/946 (94%), Gaps = 53/946 (5%)

Query: 1   MVPWVRTMGQKLKQRLRLDVGREICRQYPLFCFLLLCLSAASLLLNRYIHILMIFWSFVA 60
           MVPWVRTMGQKLKQRLRLDVGREICRQYPLFCFLLLCLSAASLLLNRYIHILMIFWSFVA
Sbjct: 1   MVPWVRTMGQKLKQRLRLDVGREICRQYPLFCFLLLCLSAASLLLNRYIHILMIFWSFVA 60

Query: 61  GVVTFYCSLGPDSLLPNIFFTIKYKPKQLGLQELFPQGHSCAVCGKVKCKRHRPSLLLEN 120
           GVVTFYCSLGPDSLLPNIFFTIKYKPKQLGLQELFPQGHSCAVCGKVKCKRHRPSLLLEN
Sbjct: 61  GVVTFYCSLGPDSLLPNIFFTIKYKPKQLGLQELFPQGHSCAVCGKVKCKRHRPSLLLEN 120

Query: 121 YQPWLDLKISSKVDASLSEV---------------------------------------- 140
           YQPWLDLKISSKVDASLSEV                                        
Sbjct: 121 YQPWLDLKISSKVDASLSEVLELVLENFVYPWYRDVTDDESFVDELRITLRFFASVLIRR 180

Query: 141 ----DIPSIITKKLLKAAMKHIEVIVKARQKVKNTEFLQQAALEEYGPELHVALRSRRDE 196
               DIPSIITKKLLKAAMKHIEVIVKARQKVKNTEFLQQAALEEYGPELHVALRSRRDE
Sbjct: 181 IHKVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEFLQQAALEEYGPELHVALRSRRDE 240

Query: 197 LHYLRKLTELLFPYILPPKATDCRSLTLLIREILSGSVFLPSLDFLADPDTVNHLLIIFI 256
           LHYLRKLTELLFPYILPPKATDCRSLTLLIREILSGSVFLPSLDFLADPDTVNHLLIIFI
Sbjct: 241 LHYLRKLTELLFPYILPPKATDCRSLTLLIREILSGSVFLPSLDFLADPDTVNHLLIIFI 300

Query: 257 DDSPPEKATEPASPLVPFLQKFAEPRNKKPSVLKLELKQIREQQDLLFRFMNFLKQEGAV 316
           DDSPPEKATEPASPLVPFLQKFAEPRNKKPSVLKLELKQIREQQDLLFRFMNFLKQEGAV
Sbjct: 301 DDSPPEKATEPASPLVPFLQKFAEPRNKKPSVLKLELKQIREQQDLLFRFMNFLKQEGAV 360

Query: 317 HVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQ 376
           HVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQ
Sbjct: 361 HVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQ 420

Query: 377 RIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRGAESPTRNSK 436
           RIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRGAESPTRNSK
Sbjct: 421 RIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRGAESPTRNSK 480

Query: 437 LNR---------NTQKRGESFGISRIGSKIKGVFKSTTMEGAMLPNYGVAEGEDDFIEEG 487
           LNR         NTQKRGESFGISRIGSKIKGVFKSTTMEGAMLPNYGVAEGEDDFIEEG
Sbjct: 481 LNRGSLSLDDFRNTQKRGESFGISRIGSKIKGVFKSTTMEGAMLPNYGVAEGEDDFIEEG 540

Query: 488 IVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKERIPVFCIDVERND 547
           IVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKERIPVFCIDVERND
Sbjct: 541 IVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKERIPVFCIDVERND 600

Query: 548 RRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEF 607
           RRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEF
Sbjct: 601 RRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEF 660

Query: 608 QEYLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMKEKGQH 667
           QEYLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMKEKGQH
Sbjct: 661 QEYLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMKEKGQH 720

Query: 668 LEPFIMNFINSCESPKPKPSRPELTILSPTSENNKKLFNDLFKNNANRAENTERKQNQNY 727
           LEPFIMNFINSCESPKPKPSRPELTILSPTSENNKKLFNDLFKNNANRAENTERKQNQNY
Sbjct: 721 LEPFIMNFINSCESPKPKPSRPELTILSPTSENNKKLFNDLFKNNANRAENTERKQNQNY 780

Query: 728 FMEVMTVEGVYDYLMYVGRVVFQVPDWLHHLLMGTRILFKNTLEMYTDYYLQCKLEQLFQ 787
           FMEVMTVEGVYDYLMYVGRVVFQVPDWLHHLLMGTRILFKNTLEMYTDYYLQCKLEQLFQ
Sbjct: 781 FMEVMTVEGVYDYLMYVGRVVFQVPDWLHHLLMGTRILFKNTLEMYTDYYLQCKLEQLFQ 840

Query: 788 EHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLLVKCIGEETKYESI 847
           EHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLLVKCIGEETKYESI
Sbjct: 841 EHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLLVKCIGEETKYESI 900

Query: 848 RLLFDGLQQPVLNKQLTYVLLDIVIQELFPELNKVQKEVTSVTSWM 893
           RLLFDGLQQPVLNKQLTYVLLDIVIQELFPELNKVQKEVTSVTSWM
Sbjct: 901 RLLFDGLQQPVLNKQLTYVLLDIVIQELFPELNKVQKEVTSVTSWM 946


>gi|38708169 sorting nexin 25 [Homo sapiens]
          Length = 840

 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 123/593 (20%), Positives = 230/593 (38%), Gaps = 137/593 (23%)

Query: 337 LSNDEMLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLF 396
           L N     + + + +IY+ + ++    +I  +  + +EIQ+   G        + +   +
Sbjct: 323 LKNANKNEIPQLVGEIYQNFFVESK--EISVEKSLYKEIQQCLVGN-------KGIEVFY 373

Query: 397 EAYEHVLSLLENVFTPMFCHSDEYFRQLLRGAESPTRNSKLNRNTQKRGESFGISRIG-- 454
           +  E V   L++ + P F  SD Y + L++  E        N++     +  G   +   
Sbjct: 374 KIQEDVYETLKDRYYPSFIVSDLYEKLLIKEEEKHASQMISNKDEMGPRDEAGEEAVDDG 433

Query: 455 ------------SKIKGVFKSTTMEGAMLPNYGVAEGEDDFI----EEGIVVMED---DS 495
                       +K++ + +    +   L +   A   D  I    ++ I+++E    D 
Sbjct: 434 TNQINEQASFAVNKLRELNEKLEYKRQALNSIQNAPKPDKKIVSKLKDEIILIEKERTDL 493

Query: 496 PVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKERIPVFCIDVERNDRRAVGHEP 555
            +    T     NL  WK SI   +  E       E  E++P + + V   +    G E 
Sbjct: 494 QLHMARTDWWCENLGMWKASITSGEVTE-------ENGEQLPCYFVMVSLQE--VGGVET 544

Query: 556 EHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLL 615
           ++W+V RR  EF  L  KL+E         +PS                        K +
Sbjct: 545 KNWTVPRRLSEFQNLHRKLSEC--------VPSL-----------------------KKV 573

Query: 616 QHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMKEKGQHLEPFIMNF 675
           Q P LS                      LP        KS+  K M++    L  F+ N 
Sbjct: 574 QLPSLSK---------------------LP-------FKSIDQKFMEKSKNQLNKFLQNL 605

Query: 676 INS---CESPKP----KPSRPELTILSPTSENN--------KKLFNDLFKNNANRAENTE 720
           ++    C+S        PS   L ++    + N        ++L  D F   +++ E TE
Sbjct: 606 LSDERLCQSEALYAFLSPSPDYLKVIDVQGKKNSFSLSSFLERLPRDFF---SHQEEETE 662

Query: 721 RKQNQNYFMEVMTVEGVYDYL-----MYVGRVVFQVPD---WLHHLLMG-TRILFKNTLE 771
              + + + +   V+G  D L     M +G + F++     W+   L+   ++ F  T+ 
Sbjct: 663 EDSDLSDYGD--DVDGRKDALAEPCFMLIGEI-FELRGMFKWVRRTLIALVQVTFGRTIN 719

Query: 772 MYTDYYLQCKLEQLFQEHRLVSLITLLRDAIFCEN-----TEPRSLQDKQKGAKQTFEEM 826
                 ++  +  +F E  LV  I + RDA +        T  RS +  Q+  ++  +++
Sbjct: 720 KQ----IRDTVSWIFSEQMLVYYINIFRDAFWPNGKLAPPTTIRSKEQSQETKQRAQQKL 775

Query: 827 MNYIPDLLVKCIGEETKYESIRLLFDGLQQPVLNKQLTYVLLDIVIQELFPEL 879
           +  IPD+L   +G++     I  +F+ LQ+   NK L Y L+++++ EL PEL
Sbjct: 776 LENIPDMLQSLVGQQNARHGIIKIFNALQETRANKHLLYALMELLLIELCPEL 828



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 37/140 (26%), Positives = 72/140 (51%), Gaps = 18/140 (12%)

Query: 116 LLLENYQPWLDLKISSKVDASLSEVDIPSIITKKLLKAAMKHIEVI--VKARQKVKNTEF 173
           LLLE++  W   +I+ ++   LS VD+  ++   +++  + H   +    AR + +   F
Sbjct: 34  LLLEDF--W---EIARQLHHRLSHVDVVKVVCNDVVRTLLTHFCDLKAANARHEEQPRPF 88

Query: 174 LQQAALEEYGPELHVALRSRRDELHYLRKLTELLFPYILPPKATDCRSLTLLIREILSGS 233
           +           LH  LR+  DE+ +L+  + +L   +LP K     SL +++ EIL+  
Sbjct: 89  V-----------LHACLRNSDDEVRFLQTCSRVLVFCLLPSKDVQSLSLRIMLAEILTTK 137

Query: 234 VFLPSLDFLADPDTVNHLLI 253
           V  P ++ L++PD +N +L+
Sbjct: 138 VLKPVVELLSNPDYINQMLL 157


>gi|17864088 sorting nexin 13 [Homo sapiens]
          Length = 957

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 81/371 (21%), Positives = 151/371 (40%), Gaps = 75/371 (20%)

Query: 548 RRAVGHEPEHWSVYRRYLEFYVLESKLTE-FHGAFPDAQLPSKRIIGPKNYEFLKSKREE 606
           RR +  E E W  YRRY +F+    ++TE F       +LP K+     + +FL+ ++++
Sbjct: 587 RRNLNSE-EMWKTYRRYSDFHDFHMRITEQFESLSSILKLPGKKTFNNMDRDFLEKRKKD 645

Query: 607 FQEYLQKLLQHPELSNSQLLA----DFLSPNG---GETQFLDKILPDV--------NLGK 651
              YLQ LL    +  S  LA    DFL       G+  F  K+   V        N+  
Sbjct: 646 LNAYLQLLLAPEMMKASPALAHYVYDFLENKAYSKGKGDFARKMDTFVNPLRNSMRNVSN 705

Query: 652 IIKSVP--------------GKLMKEKGQHLEPFIMNFINSCESPKPKPSRPELTILSPT 697
            +KS+P              GK+ +  GQ ++    +F           S PE   +S  
Sbjct: 706 AVKSLPDSLAEGMTKMSDNMGKMSERLGQDIK---QSFFKVPPLIPKTDSDPEHRRVSAQ 762

Query: 698 SENNKK----------LFNDLFKNNANRAENTERKQNQNYFMEVMTVEGVYDYLMYVGRV 747
            ++N            L +++F  +        R+  +N   +++       Y   + R 
Sbjct: 763 LDDNVDDNIPLRVMLLLMDEVF--DLKERNQWLRRNIKNLLQQLIRA----TYGDTINRK 816

Query: 748 VFQVPDWLHHLLMGTRILFKNTLEMYTDYYLQCKLEQLFQEHRLVSLITLLRDAIFCENT 807
           +    DW     M +     ++++ + D +    +               L +A+ C + 
Sbjct: 817 IVDHVDW-----MTSPEQVADSVKRFRDAFWPNGI---------------LAEAVPCRD- 855

Query: 808 EPRSLQDKQKGAKQTFEEMMNYIPDLLVKCIGEETKYESIRLLFDGLQQPVLNKQLTYVL 867
             +S++ + + A +T  +++  +PD L   IG ET  + I  +F+  Q   LN+++ YV 
Sbjct: 856 --KSIRMRTRVAGKT--KLLAIMPDELKHIIGAETTRKGILRVFEMFQHNQLNRRMVYVF 911

Query: 868 LDIVIQELFPE 878
           L+  ++ LFP+
Sbjct: 912 LEGFLETLFPQ 922



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 38/134 (28%), Positives = 64/134 (47%), Gaps = 13/134 (9%)

Query: 139 EVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEFLQQAALEEYGP---ELHVALR---- 191
           E+D     T +++     H+ V  KA+QK+   +   +   E+      E+ V +     
Sbjct: 150 EIDWQPYFTTRIVDDFGTHLRVFRKAQQKITEKDDQVKGTAEDLVDTFFEVEVEMEKEVC 209

Query: 192 ------SRRDELHYLRKLTELLFPYILPPKATDCRSLTLLIREILSGSVFLPSLDFLADP 245
                 S +DE  +LR L E+L   +LPP     + +   +REIL+  + LP ++ L+DP
Sbjct: 210 RDLVCTSPKDEEGFLRDLCEVLLYLLLPPGDFQNKIMRYFVREILARGILLPLINQLSDP 269

Query: 246 DTVNHLLIIFIDDS 259
           D +N  +I  I DS
Sbjct: 270 DYINQYVIWMIRDS 283


>gi|157502171 sorting nexin 19 [Homo sapiens]
          Length = 992

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 35/121 (28%), Positives = 64/121 (52%), Gaps = 8/121 (6%)

Query: 777 YLQCKLEQLFQEHRLVSLITLLRDAIFCENTEP------RSLQDKQKGAKQTFEEMMNYI 830
           +L+ ++  L    R V  + LL+++I+     P      R+ + K    KQ  + +M  +
Sbjct: 859 WLEVQVANLTSPQRWVQYLLLLQESIWPGGVLPKFPRPVRTQEQKLAAEKQALQSLMGVL 918

Query: 831 PDLLVKCIGEETKYESIRLLFDGLQQPVLNKQLTYVLLDIVIQELFPELNKVQKEVTSVT 890
           PDL+V+ +G      S  L+ + LQQP++N+ L Y L DI+++  F +L+   +E  + T
Sbjct: 919 PDLVVEILGVNKCRLSWGLVLESLQQPLINRHLIYCLGDIILE--FLDLSASVEESAATT 976

Query: 891 S 891
           S
Sbjct: 977 S 977



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 28/91 (30%), Positives = 48/91 (52%), Gaps = 5/91 (5%)

Query: 187 HVALRSRRDELHYLRKLTELLFPYILPPKATDCRSLTLLIREILSGSVFLPSLDFLADPD 246
           H A+ S   E+ Y R +  LL   ++P    + R+   ++ E+++ +V LP +  L+DPD
Sbjct: 199 HPAVHSPSAEVTYTRGVVNLLLQGLVPKPHLETRTGRHVVVELITCNVILPLISRLSDPD 258

Query: 247 TVNHLLIIFI----DDSPPEKATEPASPLVP 273
            + HL+++ I     D  P  A+ P  P VP
Sbjct: 259 WI-HLVLVGIFSKARDPAPCPASAPEQPSVP 288



 Score = 37.4 bits (85), Expect = 0.063
 Identities = 39/156 (25%), Positives = 69/156 (44%), Gaps = 26/156 (16%)

Query: 559 SVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNY-----------EFLKSKREEF 607
           +V RRY EF  L+++L E     PD +   K + GPK             + +++++   
Sbjct: 578 TVNRRYREFLNLQTRLEEK----PDLRKFIKNVKGPKKLFPDLPFGNMDSDRVEARKSLL 633

Query: 608 QEYLQKLLQHPELSNSQLLADFLSPN-GGETQFLDKILPDVNLGKIIKSVPGKLMKEKGQ 666
           + +L++L   PE++NS+ + +FL+ N      F+ K      + K++ S     +K    
Sbjct: 634 ESFLKQLCAIPEIANSEEVQEFLALNTDARIAFVKKPFMVSRIDKMVVSAIVDTLKTAFP 693

Query: 667 HLEPFIMNFINSCESPKPKPSRPELTILSPTSENNK 702
             EP         +SP  + S  E T   P +E  K
Sbjct: 694 RSEP---------QSPTEELSEAE-TESKPQTEGKK 719


>gi|31563383 serum/glucocorticoid regulated kinase 3 isoform 2 [Homo
           sapiens]
          Length = 464

 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 44/129 (34%), Positives = 68/129 (52%), Gaps = 14/129 (10%)

Query: 512 WKISIPYVDFFEDPSS-ERKEKKERIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVL 570
           +K S P V     PSS E +EKK+R  V+ + V      +VG     W V+RRY EF  L
Sbjct: 9   YKESCPSVSI---PSSDEHREKKKRFTVYKVLV------SVGRS--EWFVFRRYAEFDKL 57

Query: 571 ESKLTEFHGAFPDAQLPSKRIIGPK-NYEFLKSKREEFQEYLQKLLQHPELSNSQLLADF 629
            + L +   A    ++P+KRI G   + +F+K +R    E++Q L+++PEL N   +  F
Sbjct: 58  YNTLKKQFPAMA-LKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAF 116

Query: 630 LSPNGGETQ 638
           L  +  + Q
Sbjct: 117 LQMDSPKHQ 125


>gi|31563382 serum/glucocorticoid regulated kinase 3 isoform 1 [Homo
           sapiens]
          Length = 496

 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 44/129 (34%), Positives = 68/129 (52%), Gaps = 14/129 (10%)

Query: 512 WKISIPYVDFFEDPSS-ERKEKKERIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVL 570
           +K S P V     PSS E +EKK+R  V+ + V      +VG     W V+RRY EF  L
Sbjct: 9   YKESCPSVSI---PSSDEHREKKKRFTVYKVLV------SVGRS--EWFVFRRYAEFDKL 57

Query: 571 ESKLTEFHGAFPDAQLPSKRIIGPK-NYEFLKSKREEFQEYLQKLLQHPELSNSQLLADF 629
            + L +   A    ++P+KRI G   + +F+K +R    E++Q L+++PEL N   +  F
Sbjct: 58  YNTLKKQFPAMA-LKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAF 116

Query: 630 LSPNGGETQ 638
           L  +  + Q
Sbjct: 117 LQMDSPKHQ 125


>gi|75813626 serum/glucocorticoid regulated kinase 3 isoform 1 [Homo
           sapiens]
          Length = 496

 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 44/129 (34%), Positives = 68/129 (52%), Gaps = 14/129 (10%)

Query: 512 WKISIPYVDFFEDPSS-ERKEKKERIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVL 570
           +K S P V     PSS E +EKK+R  V+ + V      +VG     W V+RRY EF  L
Sbjct: 9   YKESCPSVSI---PSSDEHREKKKRFTVYKVLV------SVGRS--EWFVFRRYAEFDKL 57

Query: 571 ESKLTEFHGAFPDAQLPSKRIIGPK-NYEFLKSKREEFQEYLQKLLQHPELSNSQLLADF 629
            + L +   A    ++P+KRI G   + +F+K +R    E++Q L+++PEL N   +  F
Sbjct: 58  YNTLKKQFPAMA-LKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAF 116

Query: 630 LSPNGGETQ 638
           L  +  + Q
Sbjct: 117 LQMDSPKHQ 125


>gi|31543452 PX domain containing serine/threonine kinase [Homo
           sapiens]
          Length = 578

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 28/92 (30%), Positives = 48/92 (52%), Gaps = 3/92 (3%)

Query: 558 WSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLLQH 617
           W + RRY +F +L + L     + P   LP K++IG  + EF+  +++  Q YL  +  +
Sbjct: 50  WQIVRRYSDFDLLNNSLQIAGLSLP---LPPKKLIGNMDREFIAERQKGLQNYLNVITTN 106

Query: 618 PELSNSQLLADFLSPNGGETQFLDKILPDVNL 649
             LSN +L+  FL PN     + +  L  V++
Sbjct: 107 HILSNCELVKKFLDPNNYSANYTEIALQQVSM 138


>gi|7706706 sorting nexin 9 [Homo sapiens]
          Length = 595

 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 8/86 (9%)

Query: 546 NDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKRE 605
           N  R+V H  +H+         ++ E  L +F  A P   LP K++ G    EF+K + E
Sbjct: 278 NTNRSVNHRYKHFD--------WLYERLLVKFGSAIPIPSLPDKQVTGRFEEEFIKMRME 329

Query: 606 EFQEYLQKLLQHPELSNSQLLADFLS 631
             Q ++ ++ +HP +S S++   FL+
Sbjct: 330 RLQAWMTRMCRHPVISESEVFQQFLN 355


>gi|23238244 sorting nexin 16 isoform a [Homo sapiens]
          Length = 344

 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 30/103 (29%), Positives = 50/103 (48%), Gaps = 7/103 (6%)

Query: 528 ERKEKKERIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLP 587
           E  E++ +  V+ I V++          E W V+RRY +F  L  KL E    F  A  P
Sbjct: 116 EVMEERAKFTVYKILVKKTPE-------ESWVVFRRYTDFSRLNDKLKEMFPGFRLALPP 168

Query: 588 SKRIIGPKNYEFLKSKREEFQEYLQKLLQHPELSNSQLLADFL 630
            +      N +FL+ ++   Q +LQ L+ H +++N   + +FL
Sbjct: 169 KRWFKDNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFL 211


>gi|23238246 sorting nexin 16 isoform a [Homo sapiens]
          Length = 344

 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 30/103 (29%), Positives = 50/103 (48%), Gaps = 7/103 (6%)

Query: 528 ERKEKKERIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLP 587
           E  E++ +  V+ I V++          E W V+RRY +F  L  KL E    F  A  P
Sbjct: 116 EVMEERAKFTVYKILVKKTPE-------ESWVVFRRYTDFSRLNDKLKEMFPGFRLALPP 168

Query: 588 SKRIIGPKNYEFLKSKREEFQEYLQKLLQHPELSNSQLLADFL 630
            +      N +FL+ ++   Q +LQ L+ H +++N   + +FL
Sbjct: 169 KRWFKDNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFL 211


>gi|154091028 sorting nexin 29 [Homo sapiens]
          Length = 428

 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 20/60 (33%), Positives = 35/60 (58%)

Query: 556 EHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLL 615
           + W++YRRY EF  L  KL   +        P K+ IG K+ +F++ +R++ Q YL+ ++
Sbjct: 302 DEWNIYRRYTEFRSLHHKLQNKYPQVRAYNFPPKKAIGNKDAKFVEERRKQLQNYLRSVM 361


>gi|23943858 sorting nexin 8 [Homo sapiens]
          Length = 465

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 26/80 (32%), Positives = 42/80 (52%), Gaps = 1/80 (1%)

Query: 559 SVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLLQHP 618
           SVYRRY +F V +  L           LP KR++G    EF++++R   + ++  + +HP
Sbjct: 105 SVYRRYNDFVVFQEMLLHKFPYRMVPALPPKRMLGADR-EFIEARRRALKRFVNLVARHP 163

Query: 619 ELSNSQLLADFLSPNGGETQ 638
             S   +L  FLS +G + Q
Sbjct: 164 LFSEDVVLKLFLSFSGSDVQ 183


>gi|23111055 sorting nexin 7 isoform b [Homo sapiens]
          Length = 336

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 6/127 (4%)

Query: 554 EPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPK----NYEFLKSKREEFQE 609
           +   + V RRY +F  L+ KL E H       LP K I+       N +F++++R+   +
Sbjct: 64  DSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRKALHK 123

Query: 610 YLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDV--NLGKIIKSVPGKLMKEKGQH 667
           +L ++  HP L+ ++    FL+    E     K  P +   +G+ +++V   +   K + 
Sbjct: 124 FLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRP 183

Query: 668 LEPFIMN 674
            E   MN
Sbjct: 184 EEFMEMN 190


>gi|194294540 sorting nexin 7 isoform a [Homo sapiens]
          Length = 451

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 6/127 (4%)

Query: 554 EPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPK----NYEFLKSKREEFQE 609
           +   + V RRY +F  L+ KL E H       LP K I+       N +F++++R+   +
Sbjct: 128 DSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRKALHK 187

Query: 610 YLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDV--NLGKIIKSVPGKLMKEKGQH 667
           +L ++  HP L+ ++    FL+    E     K  P +   +G+ +++V   +   K + 
Sbjct: 188 FLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRP 247

Query: 668 LEPFIMN 674
            E   MN
Sbjct: 248 EEFMEMN 254


>gi|23111038 sorting nexin 2 [Homo sapiens]
          Length = 519

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 46/176 (26%), Positives = 67/176 (38%), Gaps = 37/176 (21%)

Query: 502 TPNTPRNLAAWKISIPYVD--FFEDPSSERKEKKERIPVFCIDVERNDRRAVGH------ 553
           TP TP  L A +I    +      D S E  E++    +F I++  +D   VG       
Sbjct: 101 TPVTPTTLIAPRIESKSMSAPVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAYM 160

Query: 554 -------------EPEHWSVYRRYLEFYVLESKLTE--FHGAFPDAQLPSKRIIG----- 593
                            +SV RR+ +F  L SKL     H  +     P K I+G     
Sbjct: 161 AYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVK 220

Query: 594 -----PKNYEFLKSKREEFQEYLQKLLQHPELSNSQLLADFLS----PNGGETQFL 640
                  + EF++ +R   + YLQ+ ++HP L     L  FL     P    TQ L
Sbjct: 221 VGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQAL 276


>gi|27501450 axin 1 isoform a [Homo sapiens]
          Length = 862

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 51/168 (30%), Positives = 71/168 (42%), Gaps = 29/168 (17%)

Query: 268 ASPLVPFLQKFAEPRNKKPSVLKLELKQIREQQDLLFRFMNFLKQEGAVHVLQFCLTVEE 327
           ASP  P+L K+AE            L  + + QD +  F  FLKQEG   +L F      
Sbjct: 76  ASPTPPYL-KWAE-----------SLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTG 123

Query: 328 FNDRILRPELSNDE-MLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQRIAEGPYID- 385
           F  R L P  SN+E  L L    + IY+ Y LD +         IV    + A   +I  
Sbjct: 124 F--RKLEPCDSNEEKRLKL---ARAIYRKYILDNN--------GIVSRQTKPATKSFIKG 170

Query: 386 -VVKLQTMRCLF-EAYEHVLSLLENVFTPMFCHSDEYFRQLLRGAESP 431
            ++K      +F +A   + + +E    P F  SD Y      G+ESP
Sbjct: 171 CIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESP 218


>gi|31083144 axin 1 isoform b [Homo sapiens]
          Length = 826

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 51/168 (30%), Positives = 71/168 (42%), Gaps = 29/168 (17%)

Query: 268 ASPLVPFLQKFAEPRNKKPSVLKLELKQIREQQDLLFRFMNFLKQEGAVHVLQFCLTVEE 327
           ASP  P+L K+AE            L  + + QD +  F  FLKQEG   +L F      
Sbjct: 76  ASPTPPYL-KWAE-----------SLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTG 123

Query: 328 FNDRILRPELSNDE-MLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQRIAEGPYID- 385
           F  R L P  SN+E  L L    + IY+ Y LD +         IV    + A   +I  
Sbjct: 124 F--RKLEPCDSNEEKRLKL---ARAIYRKYILDNN--------GIVSRQTKPATKSFIKG 170

Query: 386 -VVKLQTMRCLF-EAYEHVLSLLENVFTPMFCHSDEYFRQLLRGAESP 431
            ++K      +F +A   + + +E    P F  SD Y      G+ESP
Sbjct: 171 CIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESP 218


>gi|23111026 sorting nexin 11 [Homo sapiens]
          Length = 270

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 26/67 (38%), Positives = 37/67 (55%), Gaps = 1/67 (1%)

Query: 560 VYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLLQHPE 619
           V RRY EF  L  +L    G  P  +LP K      + EF++ +R+  Q +L+K+LQ   
Sbjct: 56  VRRRYREFVWLRKQLQRNAGLVPVPELPGKSTFFGTSDEFIEKRRQGLQHFLEKVLQSVV 115

Query: 620 -LSNSQL 625
            LS+SQL
Sbjct: 116 LLSDSQL 122


>gi|23111028 sorting nexin 11 [Homo sapiens]
          Length = 270

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 26/67 (38%), Positives = 37/67 (55%), Gaps = 1/67 (1%)

Query: 560 VYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLLQHPE 619
           V RRY EF  L  +L    G  P  +LP K      + EF++ +R+  Q +L+K+LQ   
Sbjct: 56  VRRRYREFVWLRKQLQRNAGLVPVPELPGKSTFFGTSDEFIEKRRQGLQHFLEKVLQSVV 115

Query: 620 -LSNSQL 625
            LS+SQL
Sbjct: 116 LLSDSQL 122


>gi|153791707 sorting nexin family member 30 [Homo sapiens]
          Length = 437

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 29/105 (27%), Positives = 50/105 (47%), Gaps = 4/105 (3%)

Query: 558 WSVYRRYLEFYVLESKLTEFHGAFPDAQLPSK----RIIGPKNYEFLKSKREEFQEYLQK 613
           +SV RRY +F  L SKL E         LP K     ++   + EF++++R+   ++L++
Sbjct: 127 YSVRRRYQDFDWLRSKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKR 186

Query: 614 LLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPG 658
           +  HP LS ++    FL+           I     +G+ +K V G
Sbjct: 187 ITDHPVLSFNEHFNIFLTAKDLNAYKKQGIALLTRMGESVKHVTG 231


>gi|66472382 nischarin [Homo sapiens]
          Length = 1504

 Score = 39.7 bits (91), Expect = 0.013
 Identities = 24/73 (32%), Positives = 37/73 (50%), Gaps = 1/73 (1%)

Query: 558 WSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLLQH 617
           W+V  RY +F+ L  KL           LP K+IIG  +   ++ + ++ + YLQKLL  
Sbjct: 44  WTVKHRYSDFHDLHEKLVA-ERKIDKNLLPPKKIIGKNSRSLVEKREKDLEVYLQKLLAA 102

Query: 618 PELSNSQLLADFL 630
                 ++LA FL
Sbjct: 103 FPGVTPRVLAHFL 115


>gi|23111036 sorting nexin 1 isoform c [Homo sapiens]
          Length = 474

 Score = 39.3 bits (90), Expect = 0.016
 Identities = 46/195 (23%), Positives = 77/195 (39%), Gaps = 44/195 (22%)

Query: 475 GVAEGED----DFIEEGIVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFED----PS 526
           G+ E +D    D   +  V +  DS     +  N  + LA   IS+P  +        P+
Sbjct: 76  GIHEEQDQEPQDLFADATVELSLDS-----TQNNQKKVLAKTLISLPPQEATNSSKPQPT 130

Query: 527 SERKEKKERIPVFCIDVERNDRRAVGH-------------------EPEHWSVYRRYLEF 567
            E  E++E+   F + V   D   +G                      + ++V RR+ +F
Sbjct: 131 YEELEEEEQEDQFDLTVGITDPEKIGDGMNAYVAYKVTTQTSLPLFRSKQFAVKRRFSDF 190

Query: 568 YVLESKLTEFHG--AFPDAQLPSKRIIG----------PKNYEFLKSKREEFQEYLQKLL 615
             L  KL+E H    F     P K +IG            + EFL+ +R   + YLQ+++
Sbjct: 191 LGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIV 250

Query: 616 QHPELSNSQLLADFL 630
            HP +     + +FL
Sbjct: 251 NHPTMLQDPDVREFL 265


>gi|23111034 sorting nexin 1 isoform a [Homo sapiens]
          Length = 522

 Score = 39.3 bits (90), Expect = 0.016
 Identities = 46/195 (23%), Positives = 77/195 (39%), Gaps = 44/195 (22%)

Query: 475 GVAEGED----DFIEEGIVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFED----PS 526
           G+ E +D    D   +  V +  DS     +  N  + LA   IS+P  +        P+
Sbjct: 76  GIHEEQDQEPQDLFADATVELSLDS-----TQNNQKKVLAKTLISLPPQEATNSSKPQPT 130

Query: 527 SERKEKKERIPVFCIDVERNDRRAVGH-------------------EPEHWSVYRRYLEF 567
            E  E++E+   F + V   D   +G                      + ++V RR+ +F
Sbjct: 131 YEELEEEEQEDQFDLTVGITDPEKIGDGMNAYVAYKVTTQTSLPLFRSKQFAVKRRFSDF 190

Query: 568 YVLESKLTEFHG--AFPDAQLPSKRIIG----------PKNYEFLKSKREEFQEYLQKLL 615
             L  KL+E H    F     P K +IG            + EFL+ +R   + YLQ+++
Sbjct: 191 LGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIV 250

Query: 616 QHPELSNSQLLADFL 630
            HP +     + +FL
Sbjct: 251 NHPTMLQDPDVREFL 265


>gi|23111032 sorting nexin 1 isoform b [Homo sapiens]
          Length = 457

 Score = 38.9 bits (89), Expect = 0.022
 Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 12/87 (13%)

Query: 556 EHWSVYRRYLEFYVLESKLTEFHG--AFPDAQLPSKRIIG----------PKNYEFLKSK 603
           + ++V RR+ +F  L  KL+E H    F     P K +IG            + EFL+ +
Sbjct: 114 KQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKR 173

Query: 604 REEFQEYLQKLLQHPELSNSQLLADFL 630
           R   + YLQ+++ HP +     + +FL
Sbjct: 174 RAALERYLQRIVNHPTMLQDPDVREFL 200


>gi|21493033 A-kinase anchor protein 10 precursor [Homo sapiens]
          Length = 662

 Score = 38.1 bits (87), Expect = 0.037
 Identities = 32/134 (23%), Positives = 55/134 (41%), Gaps = 24/134 (17%)

Query: 300 QDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRP-------ELSNDEMLSLHEELQKI 352
           +  LF F  ++++E AV++LQF L  + F  ++          E  ND M+        +
Sbjct: 387 ESALFYFSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMI--------L 438

Query: 353 YKTYCLDESIDKIRFDPFIVEEIQR--IAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVF 410
           Y  Y   ++   + FD  +  EI+     EG  +         C         + +E VF
Sbjct: 439 YDKYFSLQATHPLGFDDVVRLEIESNICREGGPLP-------NCFTTPLRQAWTTMEKVF 491

Query: 411 TPMFCHSDEYFRQL 424
            P F  S+ Y++ L
Sbjct: 492 LPGFLSSNLYYKYL 505


>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
          Length = 1317

 Score = 35.8 bits (81), Expect = 0.18
 Identities = 15/57 (26%), Positives = 28/57 (49%)

Query: 556  EHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQ 612
            E W+V+RRY  F  +   L   +      + P K++ G K+   +  +R   ++YL+
Sbjct: 1213 ETWTVFRRYSRFREMHKTLKLKYAELAALEFPPKKLFGNKDERVIAERRSHLEKYLR 1269


>gi|4506517 regulator of G-protein signaling 2, 24kDa [Homo sapiens]
          Length = 211

 Score = 35.4 bits (80), Expect = 0.24
 Identities = 36/149 (24%), Positives = 57/149 (38%), Gaps = 24/149 (16%)

Query: 276 QKFAEPRNKKPSVLKLELKQIREQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRP 335
           Q F +P  ++  +      ++   +  L  F  FLK E     ++F L  E+F       
Sbjct: 67  QAFIKPSPEEAQLWSEAFDELLASKYGLAAFRAFLKSEFCEENIEFWLACEDFKKTKSPQ 126

Query: 336 ELSNDEMLSLHEELQKIYKTYCLDESIDKIRFD----PFIVEEIQRIAEGPYIDVVKLQT 391
           +LS+        + +KIY  +   E+  +I  D      I + IQ    G          
Sbjct: 127 KLSS--------KARKIYTDFIEKEAPKEINIDFQTKTLIAQNIQEATSG---------- 168

Query: 392 MRCLFEAYEHVLSLLENVFTPMFCHSDEY 420
             C   A + V SL+EN   P F  S+ Y
Sbjct: 169 --CFTTAQKRVYSLMENNSYPRFLESEFY 195


>gi|224177511 sorting nexin 18 isoform c [Homo sapiens]
          Length = 591

 Score = 35.0 bits (79), Expect = 0.31
 Identities = 19/72 (26%), Positives = 33/72 (45%)

Query: 560 VYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLLQHPE 619
           V+RRY  F  L ++L E         LP K+  G    +F+  +R+    ++  +  HP 
Sbjct: 309 VHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWMNHMASHPV 368

Query: 620 LSNSQLLADFLS 631
           L+   +   FL+
Sbjct: 369 LAQCDVFQHFLT 380


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.139    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,249,498
Number of Sequences: 37866
Number of extensions: 1596537
Number of successful extensions: 4701
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 41
Number of HSP's that attempted gapping in prelim test: 4645
Number of HSP's gapped (non-prelim): 80
length of query: 893
length of database: 18,247,518
effective HSP length: 111
effective length of query: 782
effective length of database: 14,044,392
effective search space: 10982714544
effective search space used: 10982714544
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.