Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 24308420
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24308420 KLRAQ motif containing 1 isoform 2 [Homo sapiens]
(769 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24308420 KLRAQ motif containing 1 isoform 2 [Homo sapiens] 1474 0.0
gi|208431754 KLRAQ motif containing 1 isoform 1 [Homo sapiens] 1465 0.0
gi|208431757 KLRAQ motif containing 1 isoform 3 [Homo sapiens] 1380 0.0
gi|71061468 centromere protein E [Homo sapiens] 83 1e-15
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 75 2e-13
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 75 3e-13
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 74 5e-13
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 74 5e-13
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 72 3e-12
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 68 3e-11
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 68 3e-11
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 67 8e-11
gi|156104908 myosin heavy chain 6 [Homo sapiens] 66 1e-10
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 65 2e-10
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 65 2e-10
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 65 2e-10
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 65 2e-10
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 64 4e-10
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 64 4e-10
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 64 5e-10
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 64 7e-10
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 63 1e-09
gi|38044112 restin isoform b [Homo sapiens] 62 2e-09
gi|4506751 restin isoform a [Homo sapiens] 62 2e-09
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 61 3e-09
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 61 3e-09
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 61 3e-09
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 61 3e-09
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 60 1e-08
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 59 1e-08
>gi|24308420 KLRAQ motif containing 1 isoform 2 [Homo sapiens]
Length = 769
Score = 1474 bits (3815), Expect = 0.0
Identities = 769/769 (100%), Positives = 769/769 (100%)
Query: 1 MASAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMD 60
MASAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMD
Sbjct: 1 MASAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMD 60
Query: 61 SLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENE 120
SLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENE
Sbjct: 61 SLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENE 120
Query: 121 RLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLE 180
RLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLE
Sbjct: 121 RLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLE 180
Query: 181 VKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALN 240
VKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALN
Sbjct: 181 VKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALN 240
Query: 241 VPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAIDTISPLNQKF 300
VPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAIDTISPLNQKF
Sbjct: 241 VPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAIDTISPLNQKF 300
Query: 301 SQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSYICFLRKILPYQ 360
SQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSYICFLRKILPYQ
Sbjct: 301 SQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSYICFLRKILPYQ 360
Query: 361 LKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNY 420
LKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNY
Sbjct: 361 LKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNY 420
Query: 421 SSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNGA 480
SSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNGA
Sbjct: 421 SSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNGA 480
Query: 481 GKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAAYMKSLRKPLLESVP 540
GKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAAYMKSLRKPLLESVP
Sbjct: 481 GKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAAYMKSLRKPLLESVP 540
Query: 541 YEEALANRRILLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRI 600
YEEALANRRILLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRI
Sbjct: 541 YEEALANRRILLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRI 600
Query: 601 ADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVESREDLIKNHY 660
ADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVESREDLIKNHY
Sbjct: 601 ADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVESREDLIKNHY 660
Query: 661 MARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDEL 720
MARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDEL
Sbjct: 661 MARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDEL 720
Query: 721 TTTKRSYEDQLSMMSDHLCSMNETLSKQREEIDTLKMSSKGNSKKNKSR 769
TTTKRSYEDQLSMMSDHLCSMNETLSKQREEIDTLKMSSKGNSKKNKSR
Sbjct: 721 TTTKRSYEDQLSMMSDHLCSMNETLSKQREEIDTLKMSSKGNSKKNKSR 769
>gi|208431754 KLRAQ motif containing 1 isoform 1 [Homo sapiens]
Length = 780
Score = 1465 bits (3793), Expect = 0.0
Identities = 769/780 (98%), Positives = 769/780 (98%), Gaps = 11/780 (1%)
Query: 1 MASAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMD 60
MASAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMD
Sbjct: 1 MASAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMD 60
Query: 61 SLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENE 120
SLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENE
Sbjct: 61 SLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENE 120
Query: 121 RLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLE 180
RLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLE
Sbjct: 121 RLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLE 180
Query: 181 VKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALN 240
VKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALN
Sbjct: 181 VKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALN 240
Query: 241 VPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAIDTISPLNQKF 300
VPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAIDTISPLNQKF
Sbjct: 241 VPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAIDTISPLNQKF 300
Query: 301 SQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSYICFLRKILPYQ 360
SQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSYICFLRKILPYQ
Sbjct: 301 SQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSYICFLRKILPYQ 360
Query: 361 LKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNY 420
LKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNY
Sbjct: 361 LKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNY 420
Query: 421 SSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNGA 480
SSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNGA
Sbjct: 421 SSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNGA 480
Query: 481 GKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAAYMKSLRKPLLESVP 540
GKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAAYMKSLRKPLLESVP
Sbjct: 481 GKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAAYMKSLRKPLLESVP 540
Query: 541 YEEALANRRILLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRI 600
YEEALANRRILLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRI
Sbjct: 541 YEEALANRRILLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRI 600
Query: 601 ADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSL-----------VPDV 649
ADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSL VPDV
Sbjct: 601 ADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLIGTLTRTSDSEVPDV 660
Query: 650 ESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLA 709
ESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLA
Sbjct: 661 ESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLA 720
Query: 710 SQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSKQREEIDTLKMSSKGNSKKNKSR 769
SQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSKQREEIDTLKMSSKGNSKKNKSR
Sbjct: 721 SQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSKQREEIDTLKMSSKGNSKKNKSR 780
>gi|208431757 KLRAQ motif containing 1 isoform 3 [Homo sapiens]
Length = 734
Score = 1380 bits (3573), Expect = 0.0
Identities = 723/734 (98%), Positives = 723/734 (98%), Gaps = 11/734 (1%)
Query: 47 MKDQSLRKLQQEMDSLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKS 106
MKDQSLRKLQQEMDSLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKS
Sbjct: 1 MKDQSLRKLQQEMDSLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKS 60
Query: 107 VFDEDLQKKIEENERLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYM 166
VFDEDLQKKIEENERLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYM
Sbjct: 61 VFDEDLQKKIEENERLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYM 120
Query: 167 ETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKV 226
ETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKV
Sbjct: 121 ETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKV 180
Query: 227 PFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPV 286
PFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPV
Sbjct: 181 PFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPV 240
Query: 287 DSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHL 346
DSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHL
Sbjct: 241 DSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHL 300
Query: 347 TSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLA 406
TSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLA
Sbjct: 301 TSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLA 360
Query: 407 LPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTN 466
LPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTN
Sbjct: 361 LPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTN 420
Query: 467 DCILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAA 526
DCILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAA
Sbjct: 421 DCILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAA 480
Query: 527 YMKSLRKPLLESVPYEEALANRRILLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEA 586
YMKSLRKPLLESVPYEEALANRRILLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEA
Sbjct: 481 YMKSLRKPLLESVPYEEALANRRILLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEA 540
Query: 587 QLAKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSL- 645
QLAKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSL
Sbjct: 541 QLAKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLI 600
Query: 646 ----------VPDVESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALA 695
VPDVESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALA
Sbjct: 601 GTLTRTSDSEVPDVESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALA 660
Query: 696 EKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSKQREEIDTL 755
EKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSKQREEIDTL
Sbjct: 661 EKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSKQREEIDTL 720
Query: 756 KMSSKGNSKKNKSR 769
KMSSKGNSKKNKSR
Sbjct: 721 KMSSKGNSKKNKSR 734
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 82.8 bits (203), Expect = 1e-15
Identities = 167/787 (21%), Positives = 330/787 (41%), Gaps = 127/787 (16%)
Query: 1 MASAELQGKYQKLAQEYSKLRAQNQVLKKGVV------DEQANSAALKEQLKMKDQSLRK 54
+ + EL+GK L +E +K +N+ L++ V+ + L+++++ K + L
Sbjct: 713 LCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHI 772
Query: 55 LQQEMDSLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSV---FDED 111
+ E D L + RV+ L +E+ ++ + + +S+ Q Q K++ F++
Sbjct: 773 ITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQK 832
Query: 112 LQKKIEENERLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEK 171
+ +EENER++ + ++ + + S L L+TE + + TR+ E + +
Sbjct: 833 YKMVLEENERMNQEIVNLSKEAQKFD----SSLGALKTELSYKTQELQEKTREVQERLNE 888
Query: 172 LQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDT 231
++ K +LE + TL+ +E L TE+ L LEE ++ EK +D
Sbjct: 889 MEQLKEQLENRDSTLQTVEREKTLITEK-----------LQQTLEEVKTLTQEK---DDL 934
Query: 232 KYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAID 291
K Q + L R QLK + + D V +N T + R + + +
Sbjct: 935 KQLQES-----LQIERDQLK---------SDIHDTVN--MNIDTQEQLRNALESLKQHQE 978
Query: 292 TISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSYIC 351
TI+ L K S+ + N +EE + + V + + ++ LT+ +
Sbjct: 979 TINTLKSKISEEVSRNLH----MEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVK 1034
Query: 352 FLRKILPYQLK---SLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALP 408
+I+ Q K ++E+ E ++ A +L D+K+ + + Q + LL
Sbjct: 1035 D-NEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDE 1093
Query: 409 STEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDC 468
+ ++ + + G ++S+ + A +E +L +Q+L
Sbjct: 1094 LKKQQEIVAQEKNHAIKKEG-----------ELSRTCDRLAEVEEKLKEKSQQLQEKQQQ 1142
Query: 469 ILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAAYM 528
+L+ ++ KI I L E L+ K+ +M
Sbjct: 1143 LLNVQEEMSEMQKKINE-----------------------IENLKNE--LKNKELTLEHM 1177
Query: 529 KSLRKPLLESV--PYEEALA---NRRILLSSTESREGLAQQVQQSLEKISKLE-QEKEHW 582
++ R L + + YEE + R++L +S E ++ + +I Q KE
Sbjct: 1178 ETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKE-- 1235
Query: 583 MLEAQLAKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLE-PI- 640
E ++A I L KE+Q D+L+ + ++++ A + NT +++ K E P+
Sbjct: 1236 --ELKIAHIHL-KEHQETIDELRRS-------VSEKTAQIINTQDLEKSHTKLQEEIPVL 1285
Query: 641 -QSTSLVPDVESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSK 699
+ L+P+V+ + M + LT Q DS ++ R +RL L EK +
Sbjct: 1286 HEEQELLPNVKEVSE--TQETMNELELLTEQSTTKDSTTL-----ARIEMERLRLNEKFQ 1338
Query: 700 EALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSK----QREEIDTL 755
E+ EE+K ++++ +D L T K + E + + +H+ ETL+K Q ++ +L
Sbjct: 1339 ES-QEEIK----SLTKERDNLKTIKEALEVKHDQLKEHI---RETLAKIQESQSKQEQSL 1390
Query: 756 KMSSKGN 762
M K N
Sbjct: 1391 NMKEKDN 1397
Score = 63.5 bits (153), Expect = 7e-10
Identities = 111/468 (23%), Positives = 196/468 (41%), Gaps = 66/468 (14%)
Query: 4 AELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLT 63
A++Q K Q + N+ K +V E EQ K KD +L +++ EM
Sbjct: 1377 AKIQESQSKQEQSLNMKEKDNETTK--IVSEM-------EQFKPKDSALLRIEIEM---- 1423
Query: 64 FRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLH 123
L L+KR++ DE+ ++ E S + K E + K +E E L
Sbjct: 1424 ---LGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELK 1480
Query: 124 IQFFEADEQHKHVEAELRSRLATLETEAA----QHQAVVDGLTRKYMETIEKLQ--NDKA 177
+ EQ + + ELR L+ ETE + Q +A+ D L K E EK + N K
Sbjct: 1481 VAHCCLKEQEETIN-ELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQ 1539
Query: 178 KLEVKSQTLE-KEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQY 236
EV+ + E K+ KE R + +++ +L+ RL+ES E++ + +
Sbjct: 1540 ISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQES----QEEIQIMIKEKEEM 1595
Query: 237 NALNVPLHNRRHQLK--MRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSA----- 289
+ L R QLK ++I + + Q+ L E + ++ ++
Sbjct: 1596 KRVQEALQIERDQLKENTKEIVAK-MKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFE 1654
Query: 290 -----IDTISPLNQKFSQYLHENASY----------VRPLEEGML----HLFESITEDTV 330
++ I N + +Q LHEN +R +EE + L E++ E
Sbjct: 1655 TQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETIT 1714
Query: 331 TVLETTVKLKTFSEHLTSY---ICFLRKIL---PYQLKSLEEECESSLCTSALRARNLEL 384
LE +LK HL + I LR I+ ++ +++++ E S AL+A++L++
Sbjct: 1715 RDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHS--NDALKAQDLKI 1772
Query: 385 SQDMK-KMTAVFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNVGAAL 431
++++ + E+ +T L + S + D L +N L N A L
Sbjct: 1773 QEELRIAHMHLKEQQETIDKLRGIVSEKTDKL--SNMQKDLENSNAKL 1818
Score = 60.8 bits (146), Expect = 4e-09
Identities = 88/406 (21%), Positives = 175/406 (43%), Gaps = 59/406 (14%)
Query: 11 QKLAQEYSKLRAQNQVLKK--GVVDEQANSAA-LKEQLKMKDQSLRKLQQEMDSLTFRNL 67
++L + L+ Q + + K G+V E+ + + +++ L+ + L++ QE+ + + +
Sbjct: 1774 EELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLI 1833
Query: 68 QLAKRVELLQDELALSEPRGKKNKKSGESSSQLS--------------QEQKSVFDE-DL 112
L K V Q +++ E K+ K + S+L +E KSV E D
Sbjct: 1834 TLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDN 1893
Query: 113 QKKIEENERLHI-QFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEK 171
+++EE +L Q E+ ++ K + E++ L T + +H+ VD L K E +
Sbjct: 1894 LRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQ 1953
Query: 172 LQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDT 231
+ + + L+ L+K+ +E L+ +E QL R++E +++ ++K+ +
Sbjct: 1954 ISDIQKDLDKSKDELQKKIQE--LQKKELQLL----------RVKEDVNMSHKKINEMEQ 2001
Query: 232 KYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPV----- 286
Q+ A N L M+ + + L +L ++R ++ +
Sbjct: 2002 LKKQFEAQN---------LSMQSVRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLK 2052
Query: 287 ---DSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFS 343
D I T+ + + Q H+ R L +G HL ES+ E + E LK +S
Sbjct: 2053 MERDQFIATLREMIARDRQN-HQVKPEKRLLSDGQQHLTESLREKCSRIKEL---LKRYS 2108
Query: 344 EHLTSYICF------LRKILPYQLKSLEEECESSLCTSALRARNLE 383
E Y C L K + +Q K L +++L L+ +++E
Sbjct: 2109 EMDDHYECLNRLSLDLEKEIEFQ-KELSMRVKANLSLPYLQTKHIE 2153
Score = 56.6 bits (135), Expect = 8e-08
Identities = 181/806 (22%), Positives = 322/806 (39%), Gaps = 125/806 (15%)
Query: 9 KYQKLAQEYSKLRAQNQVLKKGVVDE-QANSAALKEQLKMKDQSLRKLQQEMDSLT---- 63
K +K+ +E K + +G + E +A KE+LK+ L++ Q+ +D L
Sbjct: 1200 KERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVS 1259
Query: 64 ------FRNLQLAKRVELLQDELALSE------PRGKKNKKSGESSSQLS--QEQKSVFD 109
L K LQ+E+ + P K+ ++ E+ ++L EQ + D
Sbjct: 1260 EKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKD 1319
Query: 110 EDLQKKIE-ENERLHIQFFEADEQHKHVEAELRSRLATL-ETEAAQHQAVVDGLTRKYME 167
+IE E RL+ +F E+ E+ K + E R L T+ E +H D L E
Sbjct: 1320 STTLARIEMERLRLNEKFQESQEEIKSLTKE-RDNLKTIKEALEVKH----DQLKEHIRE 1374
Query: 168 TIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQ--------LQLKTLHEDLSGRLEESL 219
T+ K+Q ++K E EK+ + ++ +E Q L+++ LS RL+ES
Sbjct: 1375 TLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQES- 1433
Query: 220 SIINEKVPFNDTKYSQYNALNVPLHNRRHQLK--MRDIAGQALAFVQDLVTALL----NF 273
++++ + L L + QLK +++I + L ++L A
Sbjct: 1434 ---HDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQE 1490
Query: 274 HTYTEQRIQIFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVL 333
T E R+ + ++ I TI + + L + EE + I+E V
Sbjct: 1491 ETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQF--NIKQISE----VQ 1544
Query: 334 ETTVKLKTFSEHLTSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTA 393
E +LK F EH RK L+S+E + L R E ++++ M
Sbjct: 1545 EKVNELKQFKEH--------RKAKDSALQSIESK------MLELTNRLQESQEEIQIMIK 1590
Query: 394 VFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQK--AAI 451
E+++ L + + L+ N ++ + + + +K + + +Q+ I
Sbjct: 1591 EKEEMKRVQEALQIERDQ----LKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEI 1646
Query: 452 EH-ELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKAASGFIS 510
EH + TQKL N I + + LT NL+ +
Sbjct: 1647 EHLKEQFETQKLNLEN--IETENIRLT-------QILHENLEEMRSVTKERDDLR----- 1692
Query: 511 PLSAECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRI-LLSSTESREGLAQQVQQSL 569
S E L+ ++ ++LR+ + + +E L + L E+ + L V +
Sbjct: 1693 --SVEETLKVERD--QLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKT 1748
Query: 570 EKISKLEQEKEHW--MLEAQLAKIKLE--------KENQRIADKLKNTGSAQLVGLAQEN 619
+IS ++++ EH L+AQ KI+ E KE Q DKL+ S + L+
Sbjct: 1749 NEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQ 1808
Query: 620 AAVSNT-AGQDEATAKAVLEPIQSTSLVPDVESREDLIKNHYMARIVELTSQLQLADSKS 678
+ N+ A E + Q +L DV + + M ++ + L SK
Sbjct: 1809 KDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSE--MEQLKKQIKDQSLTLSK- 1865
Query: 679 VHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMSDHL 738
+ L LA+K E L EEMK ++ + +D L R E+ L + D L
Sbjct: 1866 --------LEIENLNLAQKLHENL-EEMK----SVMKERDNL----RRVEETLKLERDQL 1908
Query: 739 C-SMNETLSKQ---REEIDTLKMSSK 760
S+ ET ++ ++E+ T +M SK
Sbjct: 1909 KESLQETKARDLEIQQELKTARMLSK 1934
Score = 53.5 bits (127), Expect = 7e-07
Identities = 135/738 (18%), Positives = 290/738 (39%), Gaps = 89/738 (12%)
Query: 43 EQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQ 102
E L+ K+ ++KLQ+ +DS N+ +++L ++ +P+ K + L
Sbjct: 582 ELLREKEDQIKKLQEYIDSQKLENI----KMDLSYSLESIEDPKQMKQTLFDAETVALDA 637
Query: 103 EQKSVF----DEDLQKKIEENERLH------IQFFEAD-EQHKHVEAELRSRLATLETEA 151
+++S F + +L++K++E + IQ +++ E K ++ +L L + E
Sbjct: 638 KRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEI 697
Query: 152 AQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQL--------- 202
+ +++DG K + +L+ K+ + L KE +E EE L
Sbjct: 698 TKLTSLIDGKVPKDLLCNLELE---GKITDLQKELNKEVEENEALREEVILLSELKSLPS 754
Query: 203 QLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAF 262
+++ L +++ + EE I +EK D +S+ +H + + G+
Sbjct: 755 EVERLRKEIQDKSEELHIITSEK----DKLFSEV------VHKESRVQGLLEEIGKT--- 801
Query: 263 VQDLVTALLNFHTYTEQRIQIFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLF 322
DL T N+ + T+Q Q F QK+ L EN
Sbjct: 802 KDDLATTQSNYKS-TDQEFQNFKT-----LHMDFEQKYKMVLEEN--------------- 840
Query: 323 ESITEDTVTVLETTVKLKTFSEHLTSYICFLRKILPYQLKSLEEEC-ESSLCTSALRARN 381
E + ++ V + + K + L + + + + L + + ++E E L R+
Sbjct: 841 ERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRD 900
Query: 382 LELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDI 441
L ++ T + EKLQ + + + E D L + S + V +I
Sbjct: 901 STLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNI 960
Query: 442 SKHYSQKAAIE----HELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNNLDYFIAS 497
+ A+E H+ T K + + +S + + G+ F +
Sbjct: 961 DTQEQLRNALESLKQHQETINTLKSKISEE--VSRNLHMEENTGETKDEFQQKMVGIDKK 1018
Query: 498 LSYGPKAASGFISPLSAECMLQYKKKAAAYM--KSLRKPLLESVPYEEALANRRILLSST 555
K + + +++ ++K + + K+ + +LESV +A + L +
Sbjct: 1019 QDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESV-----IAEKEQLKTDL 1073
Query: 556 ESREGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRIADKLKNTGSAQLVGL 615
+ + + Q+ L + ++++ + + + IK E E R D+L A++
Sbjct: 1074 KENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRL-----AEVEEK 1128
Query: 616 AQENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVESREDLIKNHYMARIVELTSQLQLAD 675
+E + Q + + +Q + ++E+ ++ +KN + T +L+LA
Sbjct: 1129 LKEKSQQLQEKQQQLLNVQEEMSEMQKK--INEIENLKNELKNKELTLEHMETERLELAQ 1186
Query: 676 SKSVHFYAECRALSK-RLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMM 734
+ + Y E ++++K R L E K TE ++ E+ T +++L +
Sbjct: 1187 KLNEN-YEEVKSITKERKVLKELQKSFETER-----DHLRGYIREIEATGLQTKEELKIA 1240
Query: 735 SDHLCSMNETLSKQREEI 752
HL ET+ + R +
Sbjct: 1241 HIHLKEHQETIDELRRSV 1258
Score = 47.8 bits (112), Expect = 4e-05
Identities = 146/772 (18%), Positives = 290/772 (37%), Gaps = 130/772 (16%)
Query: 46 KMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQK 105
KMK+ + ++T + +L+ + DE SE N S + + K
Sbjct: 430 KMKNSNYADQFNIPTNITTKTHKLSINLLREIDESVCSESDVFSNTLDTLSEIEWNPATK 489
Query: 106 SVFDEDLQKKIE----ENERLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGL 161
+ E+++ ++ + + L + + + + + +E +L+ + E EA + + D
Sbjct: 490 LLNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQ- 548
Query: 162 TRKYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSG------RL 215
+ + I L+N EV +Q LE E E + Q+K L E + ++
Sbjct: 549 EMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKM 608
Query: 216 EESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHT 275
+ S S+ + + P K + ++A V L +R +R + +++L T T
Sbjct: 609 DLSYSLESIEDP-KQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELAT------T 661
Query: 276 YTEQRIQIFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLET 335
Y + I Q + L LE+ + F IT+ T +
Sbjct: 662 YKQMENDI--------------QLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGK 707
Query: 336 TVKLKTFSEHLTSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVF 395
K + L I L+K L +++ E E + S L++ E+ + K++
Sbjct: 708 VPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKS 767
Query: 396 EKLQTYIALLALPSTEPDGLL------RTNYSSVLTNVGAA---LHGFHDVMKDISKHYS 446
E+L + ++E D L + +L +G L K + +
Sbjct: 768 EELH-------IITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQ 820
Query: 447 QKAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKAAS 506
+ + + ++ N+ + +V L+ A K F ++L LSY +
Sbjct: 821 NFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQK----FDSSLGALKTELSYKTQE-- 874
Query: 507 GFISPLSAECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLSSTESREGL-AQQV 565
LQ K + +++ L E +E L NR L + E + L +++
Sbjct: 875 -----------LQEKTR------EVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKL 917
Query: 566 QQSLEKISKLEQEK-------EHWMLEAQLAK----------IKLEKENQRIADKLK--- 605
QQ+LE++ L QEK E +E K I +++ + + LK
Sbjct: 918 QQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQ 977
Query: 606 ---NTGSAQLVGLAQENAAVSNTAGQ--DEATAKAV-------LEPIQSTSLVPDVESRE 653
NT +++ N + G+ DE K V LE + +L DV+ E
Sbjct: 978 ETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNE 1037
Query: 654 DLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNI 713
+ + + +++ ++LQ + L +A E+ K L E +++ +N
Sbjct: 1038 IIEQQRKIFSLIQEKNELQ-------------QMLESVIAEKEQLKTDLKENIEMTIENQ 1084
Query: 714 SRL---------QDELTTTKRSY----EDQLSMMSDHLCSMNETLSKQREEI 752
L Q E+ ++++ E +LS D L + E L ++ +++
Sbjct: 1085 EELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQL 1136
Score = 31.6 bits (70), Expect = 2.9
Identities = 50/229 (21%), Positives = 91/229 (39%), Gaps = 46/229 (20%)
Query: 15 QEYSKLRAQNQVLKKGVVDE-----QANS-------AALKEQLKMKDQSL---RKLQQEM 59
+E+ R + LK G+ E Q N+ A + E + +++S ++ +Q++
Sbjct: 2273 EEWLNTRFDIEKLKNGIQKENDRICQVNNFFNNRIIAIMNESTEFEERSATISKEWEQDL 2332
Query: 60 DSLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKS--VFDEDLQKKIE 117
SL +N +L K + L+ LA SG + +Q+ K+ V Q E
Sbjct: 2333 KSLKEKNEKLFKNYQTLKTSLA-----------SGAQVNPTTQDNKNPHVTSRATQLTTE 2381
Query: 118 ENERLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKA 177
+ L EA E H E+++ LE + I KLQ A
Sbjct: 2382 KIRELENSLHEAKESAMHKESKIIKMQKELEVTN---------------DIIAKLQ---A 2423
Query: 178 KLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKV 226
K+ ++ LEK + ++ ++ L K E++ + + I EK+
Sbjct: 2424 KVHESNKCLEKTKETIQVLQDKVALGAKPYKEEIEDLKMKLVKIDLEKM 2472
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 75.1 bits (183), Expect = 2e-13
Identities = 159/782 (20%), Positives = 325/782 (41%), Gaps = 77/782 (9%)
Query: 3 SAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSL 62
+AEL K +KL E S+L KK + D + A ++++ + ++ L +EM L
Sbjct: 937 NAELTAKKRKLEDECSEL-------KKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 989
Query: 63 TFRNLQLAKRVELLQD--ELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENE 120
+L K + LQ+ + L + + +++K + + +++ EQ+ +DL+ +E+ +
Sbjct: 990 DETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQV---DDLEGSLEQEK 1046
Query: 121 RLHIQFFE-----------ADEQHKHVE---AELRSRLATLETEAAQHQAVVDGLTRKYM 166
++ + A E +E +L +L E E + Q+ ++ M
Sbjct: 1047 KIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGM 1106
Query: 167 ETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKV 226
+ +K++ +A++E + +E E + R + E+ + L E++S RLEE+ + ++
Sbjct: 1107 QLQKKIKELQARIEELEEEIEAE-RASRAKAEKQRSDLSRELEEISERLEEAGGATSAQI 1165
Query: 227 PFNDTKYSQYNALNVPLHNR--RHQLKMRDIAGQALAFVQDLVTALLNFHTY-------- 276
N + +++ + L +H+ + + V +L + N
Sbjct: 1166 EMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEK 1225
Query: 277 TEQRIQIFPVDSAIDTISPLN---QKFSQYLHENASYVRPLEEGMLHLFESITEDTVTV- 332
+E +++I + S ++T+S +K + L + S ++ EE L +T +
Sbjct: 1226 SEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQ 1285
Query: 333 LETTVKLKTFSEH--LTSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQ-DMK 389
E+ + E L S + ++ Q++ L+ + E + + A L+ S+ D
Sbjct: 1286 TESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCD 1345
Query: 390 KMTAVFEKLQTYIALLALPSTEPDGLL---RTNYSS----VLTNVGAALHGFHDVMKDIS 442
+ +E+ Q A L ++ + + RT Y + + A ++D
Sbjct: 1346 LLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAE 1405
Query: 443 KHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNNLDYFIASLSYGP 502
+H A L Q+L + ++ V TN A N D +A
Sbjct: 1406 EHVEAVNAKCASLEKTKQRLQNEVEDLMID-VERTNAACAALDKKQRNFDKILAEWKQKC 1464
Query: 503 KAASGFISPLSAE---CMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLSSTESRE 559
+ + E + K AY +SL + LE++ E + I + + E
Sbjct: 1465 EETHAELEASQKESRSLSTELFKIKNAYEESLDQ--LETLKRENKNLQQEISDLTEQIAE 1522
Query: 560 GLAQQVQQSLEKISK-LEQEKEHWMLEAQLAKIKLEKEN---QRIADKLKNTGSAQLVGL 615
G +++ + LEKI K +EQEK + A+ LE E RI +L S +
Sbjct: 1523 G-GKRIHE-LEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKI 1580
Query: 616 AQENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVESREDLI--KNHYMARIVELTSQLQL 673
A+++ + Q + ++E +QST L ++ SR D I K + E+ QL
Sbjct: 1581 AEKDEEID----QMKRNHIRIVESMQST-LDAEIRSRNDAIRLKKKMEGDLNEMEIQLNH 1635
Query: 674 AD---SKSVHFYAECRALSKRLAL----AEKSKEALTEEMKLASQNISRLQDELTTTKRS 726
A+ ++++ Y +A+ K L A +S+E L E++ + + + LQ E+ + +
Sbjct: 1636 ANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRAT 1695
Query: 727 YE 728
E
Sbjct: 1696 LE 1697
Score = 74.7 bits (182), Expect = 3e-13
Identities = 148/742 (19%), Positives = 290/742 (39%), Gaps = 76/742 (10%)
Query: 19 KLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQD 78
KL ++ ++ +D + + L E+LK K+ + LQ +++ +QL K+++ LQ
Sbjct: 1058 KLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQA 1117
Query: 79 ELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEADEQHKHVEA 138
+ E + ++ +S +++Q+S +L++ E E E +K EA
Sbjct: 1118 RIEELE----EEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREA 1173
Query: 139 ELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTE 198
E + LE QH+A L +K+ +++ +L L+ Q LEKE E ++ +
Sbjct: 1174 EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID 1233
Query: 199 ECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQ 258
+ ++T+ + G LE+ + +++ TK + L L +R +L+
Sbjct: 1234 DLASNMETVSK-AKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYS 1292
Query: 259 ALAFVQDLVTALLN--FHTYTEQRIQI-FPVDSAIDTISPLNQKFSQYLHE---NASYVR 312
+D + + L+ +T+Q ++ ++ I S L H+
Sbjct: 1293 RQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYE 1352
Query: 313 PLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSYICFLRKILPYQLKSLEEECESSL 372
+E L ++++ V + K +T + T + +K L +L+ EE E
Sbjct: 1353 EEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVE--- 1409
Query: 373 CTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNVGAALH 432
A+ A+ L + +++ E L + RTN + AAL
Sbjct: 1410 ---AVNAKCASLEKTKQRLQNEVEDLMIDVE-------------RTNAAC------AALD 1447
Query: 433 GFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNNLD 492
I + QK H A+QK +L+ KI + + +LD
Sbjct: 1448 KKQRNFDKILAEWKQKCEETHAELEASQK----------ESRSLSTELFKIKNAYEESLD 1497
Query: 493 YFIASLSYGPKAASGFISPLSAECM--------LQYKKKAAAYMKSLRKPLLESVPYEEA 544
+ +L K IS L+ + L+ KK KS + LE
Sbjct: 1498 Q-LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLE 1556
Query: 545 LANRRILLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKE----NQRI 600
+IL E + ++ ++ EK +++Q K + + + + L+ E N I
Sbjct: 1557 HEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAI 1616
Query: 601 ADKLKNTGSAQLVGLAQENA-AVSNTAGQDEATAKAVLEPIQSTSLVPDVESREDLIKNH 659
K K G + + +A ++ A ++ +A+L+ Q L + S+ED
Sbjct: 1617 RLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQ-LHLDDALRSQED----- 1670
Query: 660 YMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDE 719
L QL + + ++ AE L L E+S++ +E+ AS+ + L +
Sbjct: 1671 -------LKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQ 1723
Query: 720 ---LTTTKRSYEDQLSMMSDHL 738
L TK+ E +S + +
Sbjct: 1724 NTSLINTKKKLETDISQIQGEM 1745
Score = 52.0 bits (123), Expect = 2e-06
Identities = 144/786 (18%), Positives = 300/786 (38%), Gaps = 133/786 (16%)
Query: 4 AELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLT 63
A ++ +++K +E +K A+ + L++ +V L+ Q++ + SL ++ D L
Sbjct: 854 ANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLI 913
Query: 64 FRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDE--DLQKKIEENER 121
+QL +++ + + E E +++L+ +++ + DE +L+K I++
Sbjct: 914 KTKIQLEAKIKEVTERAEDEE----------EINAELTAKKRKLEDECSELKKDIDD--- 960
Query: 122 LHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYM---ETIEKLQNDKAK 178
L LA +E E + V LT + ETI KL +K
Sbjct: 961 ------------------LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKA 1002
Query: 179 L-EVKSQTLEK-EAKECRLRT-EECQLQLKTLHEDLSGRLEESLSIINE-----KVPFND 230
L E QTL+ +A+E ++ T + +++L+ +DL G LE+ I + + D
Sbjct: 1003 LQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGD 1062
Query: 231 TKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAI 290
K +Q + +++ N + QL + ++ ++ + S I
Sbjct: 1063 LKLAQESTMDI--ENDKQQLDEK----------------------LKKKEFEMSGLQSKI 1098
Query: 291 DTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSYI 350
+ L + + + E + + LEE + E + K +
Sbjct: 1099 EDEQALGMQLQKKIKELQARIEELEEEI-------------EAERASRAKAEKQ------ 1139
Query: 351 CFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPST 410
R L +L+ + E E + + +E++ KK A F+K++ + L
Sbjct: 1140 ---RSDLSRELEEISERLEEA---GGATSAQIEMN---KKREAEFQKMRRDLEEATLQHE 1190
Query: 411 EPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCIL 470
LR ++ + +G + V + + K S+ +L + + + +
Sbjct: 1191 ATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLE 1250
Query: 471 SSVVALTNGAGKIASFFSNN---LDYFIASLSYGPKAASGFISPLSAECML-----QYKK 522
AL + +I + ++ A + + + L + L + K+
Sbjct: 1251 KMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQ 1310
Query: 523 KAAAYMKSLRKPLLESVPYEEALANRRILLSSTESREGLAQQVQQSLEK-------ISKL 575
++ L++ L E + + ALA+ L SS + L +Q ++ E +SK
Sbjct: 1311 AFTQQIEELKRQLEEEIKAKSALAHA--LQSSRHDCDLLREQYEEEQEAKAELQRAMSKA 1368
Query: 576 EQEKEHWMLEAQLAKIKLEKENQRIADKLKNTGSAQLVGLAQENA-AVSNTAGQDEATAK 634
E W + + I+ +E + KL AQ + A+E+ AV+ E T +
Sbjct: 1369 NSEVAQWRTKYETDAIQRTEELEEAKKKL-----AQRLQDAEEHVEAVNAKCASLEKTKQ 1423
Query: 635 AVLEPIQSTSLVPDVESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLAL 694
+ ++ L+ DVE A L + + D + +C L
Sbjct: 1424 RLQNEVED--LMIDVERTN--------AACAALDKKQRNFDKILAEWKQKCEETHAELEA 1473
Query: 695 AEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSKQREEIDT 754
++K +L+ E+ D+L T KR ++ +SD + E +++ + I
Sbjct: 1474 SQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISD----LTEQIAEGGKRIHE 1529
Query: 755 LKMSSK 760
L+ K
Sbjct: 1530 LEKIKK 1535
Score = 43.5 bits (101), Expect = 7e-04
Identities = 53/237 (22%), Positives = 98/237 (41%), Gaps = 18/237 (7%)
Query: 533 KPLLESVPYEEALANRRILLSSTESREGLAQQVQQSL-EKISKLEQEKEHWMLEAQLAKI 591
KPLL+S E+ +AN + T+ + ++ L EK+ L QEK L+ Q
Sbjct: 841 KPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEAD 900
Query: 592 KL----EKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVP 647
L E+ +Q I K++ + V E+ N E TAK + + L
Sbjct: 901 SLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINA----ELTAKKRKLEDECSELKK 956
Query: 648 DVESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMK 707
D++ E + ++ + ++K + E L + +A K K+AL E +
Sbjct: 957 DIDDLE--------LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQ 1008
Query: 708 LASQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSKQREEIDTLKMSSKGNSK 764
++ +D++ T ++ + +L D L E K R +++ K +G+ K
Sbjct: 1009 QTLDDLQAEEDKVNTLTKA-KIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLK 1064
Score = 35.8 bits (81), Expect = 0.15
Identities = 74/339 (21%), Positives = 133/339 (39%), Gaps = 41/339 (12%)
Query: 43 EQLKMKDQSLRKLQQEMDSLTFRNLQLAKRV-ELLQDELALSEPRGKKNKKSGESSSQLS 101
+QL+ + + LQQE+ LT + + KR+ EL + + + + + + E+ + L
Sbjct: 1497 DQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLE 1556
Query: 102 QEQKSVFDEDL---QKKIEENERLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVV 158
E+ + L Q K E + ++ + E D+ ++ + S +TL+ E
Sbjct: 1557 HEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRN--- 1613
Query: 159 DGLTRKYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLK--TLHEDLSGRLE 216
D + K +K++ D ++E++ + A E Q LK LH D + R +
Sbjct: 1614 DAIRLK-----KKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQ 1668
Query: 217 ESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQL----KMRDIAGQALAFVQDLVTALLN 272
E L E++ + + N L + R L + R IA Q L + V L
Sbjct: 1669 EDL---KEQLAMVERR---ANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLL-- 1720
Query: 273 FHTYTEQRIQIFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTV 332
HT S I+T L SQ E ++ ++IT D +
Sbjct: 1721 -HTQN---------TSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAIT-DAAMM 1769
Query: 333 LETTVKLKTFSEHLTSYICFLRKILPYQLKSLEEECESS 371
E K + S HL ++K L +K L+ + +
Sbjct: 1770 AEELKKEQDTSAHLER----MKKNLEQTVKDLQHRLDEA 1804
Score = 31.6 bits (70), Expect = 2.9
Identities = 28/106 (26%), Positives = 52/106 (49%), Gaps = 8/106 (7%)
Query: 15 QEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVE 74
++ KL A+ + L+ V EQ + E +K LRK ++++ LT++ + K +
Sbjct: 1814 KQIQKLEARVRELEGEVESEQKRNV---EAVK----GLRKHERKVKELTYQTEEDRKNIL 1866
Query: 75 LLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENE 120
LQD + + + K K+ E + + S S F +Q ++EE E
Sbjct: 1867 RLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKF-RRIQHELEEAE 1911
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 74.7 bits (182), Expect = 3e-13
Identities = 149/744 (20%), Positives = 286/744 (38%), Gaps = 80/744 (10%)
Query: 19 KLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQD 78
KL ++ ++ +D + + L E+LK K+ + LQ +++ +QL K+++ LQ
Sbjct: 1058 KLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQA 1117
Query: 79 ELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEADEQHKHVEA 138
+ E + ++ +S +++Q+S +L++ E E E +K EA
Sbjct: 1118 RIEELE----EEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREA 1173
Query: 139 ELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTE 198
E + LE QH+A L +K+ +++ +L L+ Q LEKE E ++
Sbjct: 1174 EFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEIN 1233
Query: 199 ECQLQLKTL------HEDLSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNR----RH 248
+ ++T+ E + LE+ LS I K ++ +A LH
Sbjct: 1234 DLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSR 1293
Query: 249 QLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAIDTISPLNQKFSQYLHENA 308
QL +D L+ + T + E + Q+ A T++ Q
Sbjct: 1294 QLDEKDAMVSQLSRGKQAFTQQIE-----ELKRQLEEETKAKSTLAHALQSARHDCDLLR 1348
Query: 309 SYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSYICFLRKILPYQLKSLEEEC 368
+E L +++ V + K +T + T + +K L +L+ EE
Sbjct: 1349 EQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHV 1408
Query: 369 E--SSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNYSSVLTN 426
E +S C S L L +++ + E+ + A +AL +
Sbjct: 1409 EAVNSKCAS-LEKTKQRLQNEVEDLMIDVER--SNAACIALDKKQ--------------- 1450
Query: 427 VGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIASF 486
F V+ + + Y + A EL A+QK +L+ K+ +
Sbjct: 1451 -----RNFDKVLAEWKQKYEETQA---EL-EASQK----------ESRSLSTELFKVKNA 1491
Query: 487 FSNNLDYFIASLSYGPKAASGFISPLSAECM--------LQYKKKAAAYMKSLRKPLLES 538
+ +LD+ + +L K IS L+ + L+ KK + KS + LE
Sbjct: 1492 YEESLDH-LETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEE 1550
Query: 539 VPYEEALANRRILLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQ 598
+IL E + ++ ++ EK +L+Q K + + + + L+ E +
Sbjct: 1551 AEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIR 1610
Query: 599 RIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVESR-EDLIK 657
D L+ ++ G E N A + A A L Q ++ D + +D I+
Sbjct: 1611 SRNDALRI--KKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQ--GILKDTQLHLDDAIR 1666
Query: 658 NHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQ 717
+L QL + + ++ AE L L E+ ++ +E+ AS+ + L
Sbjct: 1667 GQ-----DDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLH 1721
Query: 718 DE---LTTTKRSYEDQLSMMSDHL 738
+ L TK+ E +S + +
Sbjct: 1722 TQNTSLINTKKKLETDISQIQGEM 1745
Score = 43.9 bits (102), Expect = 6e-04
Identities = 57/243 (23%), Positives = 94/243 (38%), Gaps = 47/243 (19%)
Query: 533 KPLLESVPYEEALANRRILLSSTESREGLAQQVQQSL-EKISKLEQEKEHWMLEAQLAKI 591
KPLL+S E+ +AN + T+ + ++ L EK+ L QEK L+ Q
Sbjct: 841 KPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEAD 900
Query: 592 KLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVES 651
L +R +K T Q EA K V E E
Sbjct: 901 ALADAEERCDQLIK-------------------TKIQLEAKIKEVTE---------RAED 932
Query: 652 REDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEA-------LTE 704
E++ ELT++ + + + + L LA EK K A LTE
Sbjct: 933 EEEI--------NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTE 984
Query: 705 EMKLASQNISRLQDELTTTKRSYE---DQLSMMSDHLCSMNETLSKQREEIDTLKMSSKG 761
EM + I++L E + +++ D L M D + ++ + +K +++D L+ S +
Sbjct: 985 EMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQ 1044
Query: 762 NSK 764
K
Sbjct: 1045 EKK 1047
Score = 40.0 bits (92), Expect = 0.008
Identities = 51/227 (22%), Positives = 97/227 (42%), Gaps = 26/227 (11%)
Query: 551 LLSSTESREGLAQQVQQSLE----KISKLEQEKE---HWMLEAQLAKIKLEKENQRIADK 603
L E + LA Q+Q+ ++ +I +LE+E E +A+ + L +E + I+++
Sbjct: 1094 LQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISER 1153
Query: 604 LKNTG---SAQLVGLAQENAA-------VSNTAGQDEATAKA--------VLEPIQSTSL 645
L+ G SAQ+ + A + + Q EATA A V E +
Sbjct: 1154 LEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDS 1213
Query: 646 VPDVESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEE 705
+ V+ + + K+ I +L S ++ +F CR L +L+ + +E
Sbjct: 1214 LQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRL 1273
Query: 706 MKLASQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSKQREEI 752
+ S +RL E R +++ +M+S L + ++Q EE+
Sbjct: 1274 INELSAQKARLHTESGEFSRQLDEKDAMVS-QLSRGKQAFTQQIEEL 1319
Score = 33.9 bits (76), Expect = 0.59
Identities = 47/266 (17%), Positives = 102/266 (38%), Gaps = 67/266 (25%)
Query: 7 QGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAA-LKEQLKMKDQSLRKLQQEMDSLTFR 65
+ ++QK+ ++ + Q++ + + A+S A L EQ+ + +KL++E L
Sbjct: 1172 EAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKME 1231
Query: 66 NLQLAKRVEL--------------LQDELA---------------LSEPRGKKNKKSGES 96
LA +E L+D+L+ LS + + + +SGE
Sbjct: 1232 INDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEF 1291
Query: 97 SSQLSQEQKSVFD------------EDLQKKIEENERLHIQFFEADEQHKH--------- 135
S QL ++ V E+L++++EE + A + +H
Sbjct: 1292 SRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQY 1351
Query: 136 -----VEAELRSRLATL-----------ETEAAQHQAVVDGLTRKYMETIEKLQNDKAKL 179
+AEL+ ++ ET+A Q ++ +K + ++ + +
Sbjct: 1352 EEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAV 1411
Query: 180 EVKSQTLEKEAKECRLRTEECQLQLK 205
K +LEK + + E+ + ++
Sbjct: 1412 NSKCASLEKTKQRLQNEVEDLMIDVE 1437
Score = 30.8 bits (68), Expect = 5.0
Identities = 27/104 (25%), Positives = 51/104 (49%), Gaps = 8/104 (7%)
Query: 15 QEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVE 74
++ KL A+ + L+ V EQ ++ E +K LRK ++ + LT++ + K +
Sbjct: 1814 KQIQKLEARVRELESEVESEQKHNV---EAVK----GLRKHERRVKELTYQTEEDRKNIL 1866
Query: 75 LLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEE 118
LQD + + + K K+ E + + S + F LQ ++EE
Sbjct: 1867 RLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKF-RKLQHELEE 1909
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 73.9 bits (180), Expect = 5e-13
Identities = 150/756 (19%), Positives = 298/756 (39%), Gaps = 104/756 (13%)
Query: 19 KLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQD 78
KL ++ ++ ++D + L E+LK K+ + LQ +++ +QL K+++ LQ
Sbjct: 1060 KLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQA 1119
Query: 79 ELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEADEQHKHVEA 138
+ E + ++ +S +++Q+S +L++ E E E +K EA
Sbjct: 1120 RIEELE----EEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREA 1175
Query: 139 ELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTE 198
E + LE QH+A L +K+ +++ +L L+ Q LEKE E ++ +
Sbjct: 1176 EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID 1235
Query: 199 ECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQ 258
+ ++T+ + G LE+ + +++ +LK ++ Q
Sbjct: 1236 DLASNVETVSK-AKGNLEKMCRTLEDQL---------------------SELKSKEEEQQ 1273
Query: 259 ALAFVQDLVTALLNFHTYTEQRIQIFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGM 318
L + DL T QR + + +FS+ L E + V L G
Sbjct: 1274 RL--INDL----------TAQR----------GRLQTESGEFSRQLDEKEALVSQLSRGK 1311
Query: 319 LHLFESITEDTVTVLETTVKLKTFSEHL---TSYICFLRKILPYQLKSLEEECESSL-CT 374
F E+ LE +K K H + + C L + + EEE ES
Sbjct: 1312 -QAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLR------EQYEEEQESKAELQ 1364
Query: 375 SALRARNLELSQ-------DMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNV 427
AL N E++Q D + T E+ + +A + E + +S+
Sbjct: 1365 RALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTK 1424
Query: 428 GAALHGFHDVMKDISKHYSQKAAIEHE-------LPTATQKLITTN---DCILSSVVALT 477
+ D+M D+ + + AA++ + L QK T+ + +L
Sbjct: 1425 QRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLG 1484
Query: 478 NGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAAYMKSLRKPLLE 537
KI + + +LD + +L K IS L+ E + + K+ K ++ E
Sbjct: 1485 TELFKIKNAYEESLDQ-LETLKRENKNLQQEISDLT-EQIAEGGKRIHELEKIKKQVEQE 1542
Query: 538 SVPYEEALANRRILLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKEN 597
+ AL +S E EG ++Q L ++ + E + + E +L++ +
Sbjct: 1543 KCELQAALEEAE---ASLEHEEGKILRIQLELNQV---KSEVDRKIAEKDEEIDQLKRNH 1596
Query: 598 QRIADKLKNTGSAQL------VGLAQE-----NAAVSNTAGQDEATAKAVLEPIQSTSLV 646
RI + +++T A++ + L ++ N + A+A+ + ++
Sbjct: 1597 IRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGIL 1656
Query: 647 PDVESR-EDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEE 705
D + +D +++ +L QL + + ++ AE L L E+S++ +E
Sbjct: 1657 KDTQIHLDDALRSQ-----EDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQE 1711
Query: 706 MKLASQNISRLQDE---LTTTKRSYEDQLSMMSDHL 738
+ AS+ + L + L TK+ E +S M +
Sbjct: 1712 LLDASERVQLLHTQNTSLINTKKKLETDISQMQGEM 1747
Score = 68.9 bits (167), Expect = 2e-11
Identities = 164/788 (20%), Positives = 324/788 (41%), Gaps = 89/788 (11%)
Query: 3 SAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSL 62
+AEL K +KL E S+L KK + D + A ++++ + ++ L +EM L
Sbjct: 939 NAELTAKKRKLEDECSEL-------KKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 991
Query: 63 TFRNLQLAKRVELLQD--ELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENE 120
+L K + LQ+ + L + + +++K + + +++ EQ+ +DL+ +E+ +
Sbjct: 992 DETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQV---DDLEGSLEQEK 1048
Query: 121 RLHIQFFE-----------ADEQHKHVEAE---LRSRLATLETEAAQHQAVVDGLTRKYM 166
+L + A E +E E L +L E E + Q+ ++ +
Sbjct: 1049 KLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGI 1108
Query: 167 ETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKV 226
+ +K++ +A++E + +E E + R + E+ + L E++S RLEE+ + ++
Sbjct: 1109 QLQKKIKELQARIEELEEEIEAE-RASRAKAEKQRSDLSRELEEISERLEEAGGATSAQI 1167
Query: 227 PFNDTKYSQYNALNVPLHNR--RHQLKMRDIAGQALAFVQDLVTALLNFHTY-------- 276
N + +++ + L +H+ + + V +L + N
Sbjct: 1168 EMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEK 1227
Query: 277 TEQRIQIFPVDSAIDTISPLN---QKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVL 333
+E +++I + S ++T+S +K + L + S ++ EE L +T +
Sbjct: 1228 SEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQ 1287
Query: 334 ETTVKLK---TFSEHLTSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQ-DMK 389
+ + E L S + ++ Q++ L+ + E + A L+ S+ D
Sbjct: 1288 TESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCD 1347
Query: 390 KMTAVFEKLQTYIALL--ALPSTEPD-GLLRTNYSSVLTNVGAALHGFHDVMKDISKHYS 446
+ +E+ Q A L AL + RT Y T+ + K +++
Sbjct: 1348 LLREQYEEEQESKAELQRALSKANTEVAQWRTKYE---TDAIQRTEELEEAKKKLAQRL- 1403
Query: 447 QKAAIEH---------ELPTATQKLIT-TNDCILSSVVALTNGAGKIASFFSNNLDYFIA 496
+AA EH L Q+L D +L V TN A N D +A
Sbjct: 1404 -QAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLD--VERTNAACAALDKKQRNFDKILA 1460
Query: 497 SLSYGPKAASGFISPLSAECM---LQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLS 553
+ + E + K AY +SL + LE++ E + I
Sbjct: 1461 EWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ--LETLKRENKNLQQEISDL 1518
Query: 554 STESREGLAQQVQQSLEKISK-LEQEKEHWMLEAQLAKIKLEKEN---QRIADKLKNTGS 609
+ + EG +++ + LEKI K +EQEK + A+ LE E RI +L S
Sbjct: 1519 TEQIAEG-GKRIHE-LEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKS 1576
Query: 610 AQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVESREDLI--KNHYMARIVEL 667
+A+++ + Q + ++E +QST L ++ SR D I K + E+
Sbjct: 1577 EVDRKIAEKDEEID----QLKRNHIRIVESMQST-LDAEIRSRNDAIRLKKKMEGDLNEM 1631
Query: 668 TSQLQLAD---SKSVHFYAECRALSK----RLALAEKSKEALTEEMKLASQNISRLQDEL 720
QL A+ ++++ Y + + K L A +S+E L E++ + + + LQ E+
Sbjct: 1632 EIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEI 1691
Query: 721 TTTKRSYE 728
+ + E
Sbjct: 1692 EELRATLE 1699
Score = 57.0 bits (136), Expect = 6e-08
Identities = 161/826 (19%), Positives = 315/826 (38%), Gaps = 161/826 (19%)
Query: 4 AELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLT 63
A ++ ++QK+ E +K A+ + L++ +V L+ Q++ + + L ++ D L
Sbjct: 856 ATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLI 915
Query: 64 FRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDE--DLQKKIEENER 121
+QL +++ + + E E +++L+ +++ + DE +L+K I++
Sbjct: 916 KTKIQLEAKIKEVTERAEDEE----------EINAELTAKKRKLEDECSELKKDIDD--- 962
Query: 122 LHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYM---ETIEKLQNDKAK 178
L LA +E E + V LT + ETI KL +K
Sbjct: 963 ------------------LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKA 1004
Query: 179 L-EVKSQTLEK-EAKECRLRT-EECQLQLKTLHEDLSGRLEES------LSIINEKVPFN 229
L E QTL+ +A+E ++ T + +++L+ +DL G LE+ L K+
Sbjct: 1005 LQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLE-G 1063
Query: 230 DTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSA 289
D K +Q + +++ N + QL + ++ +I + S
Sbjct: 1064 DLKLAQESIMDI--ENEKQQLDEK----------------------LKKKEFEISNLQSK 1099
Query: 290 IDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSY 349
I+ L + + + E + + LEE + E + K +
Sbjct: 1100 IEDEQALGIQLQKKIKELQARIEELEEEI-------------EAERASRAKAEKQ----- 1141
Query: 350 ICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPS 409
R L +L+ + E E + + +E++ KK A F+K++ + L
Sbjct: 1142 ----RSDLSRELEEISERLEEA---GGATSAQIEMN---KKREAEFQKMRRDLEEATLQH 1191
Query: 410 TEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQ--------- 460
LR ++ + +G + V + + K S+ +L + +
Sbjct: 1192 EATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNL 1251
Query: 461 -KLITTNDCILSSVVA-----------LTNGAGKI---ASFFSNNLDY---FIASLSYGP 502
K+ T + LS + + LT G++ + FS LD ++ LS G
Sbjct: 1252 EKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGK 1311
Query: 503 KAASGFISPLSAECMLQYKKKAA---AYMKSLRKPLLESVPYEE-----ALANRRILLSS 554
+A + I L + + K K A A S L YEE A R + ++
Sbjct: 1312 QAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKAN 1371
Query: 555 TESREGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRIA------DKLKNTG 608
TE + + ++++ +LE+ K+ Q A+ +E N + A +L+N
Sbjct: 1372 TEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEV 1431
Query: 609 SAQLVGLAQENAAVSNTAGQDEATAKAVLE---PIQSTSLVPDVESRED--------LIK 657
++ + + NAA + + K + E + T + +E IK
Sbjct: 1432 EDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIK 1491
Query: 658 NHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQ 717
N Y E QL+ ++ + E L++++A K L + K Q LQ
Sbjct: 1492 NAY----EESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQ 1547
Query: 718 DELTTTKRSYEDQLSMMSDHLCSMNET-------LSKQREEIDTLK 756
L + S E + + +N+ ++++ EEID LK
Sbjct: 1548 AALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLK 1593
Score = 40.8 bits (94), Expect = 0.005
Identities = 49/247 (19%), Positives = 108/247 (43%), Gaps = 36/247 (14%)
Query: 6 LQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFR 65
LQ + ++L + ++ ++ ++D L Q + +KL+ ++
Sbjct: 1687 LQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDIS----- 1741
Query: 66 NLQLAKRVELLQDELALSEPRGKKN-----------KKSGESSSQLSQEQKSVFD--EDL 112
Q+ +E + E +E + KK KK ++S+ L + +K++ +DL
Sbjct: 1742 --QMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDL 1799
Query: 113 QKKIEENERLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGL----------- 161
Q +++E E+L ++ +Q + +EA +R +E+E ++ V GL
Sbjct: 1800 QLRLDEAEQLALK--GGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELT 1857
Query: 162 --TRKYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESL 219
T + + I +LQ+ KL+ K ++ +++A+E ++ + + L +L EE
Sbjct: 1858 YQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELE-EAEERA 1916
Query: 220 SIINEKV 226
I +V
Sbjct: 1917 DIAESQV 1923
Score = 32.3 bits (72), Expect = 1.7
Identities = 28/124 (22%), Positives = 54/124 (43%), Gaps = 3/124 (2%)
Query: 628 QDEATAKAVLEPIQSTSLVPDVESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRA 687
++ AT K + I+ L R++L + M +++ + LQL A+
Sbjct: 853 KEMATMKEEFQKIKD-ELAKSEAKRKELEEK--MVTLLKEKNDLQLQVQAEAEGLADAEE 909
Query: 688 LSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSK 747
+L + EA +E+ +++ + ELT KR ED+ S + + + TL+K
Sbjct: 910 RCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAK 969
Query: 748 QREE 751
+E
Sbjct: 970 VEKE 973
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 73.9 bits (180), Expect = 5e-13
Identities = 150/756 (19%), Positives = 298/756 (39%), Gaps = 104/756 (13%)
Query: 19 KLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQD 78
KL ++ ++ ++D + L E+LK K+ + LQ +++ +QL K+++ LQ
Sbjct: 1060 KLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQA 1119
Query: 79 ELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEADEQHKHVEA 138
+ E + ++ +S +++Q+S +L++ E E E +K EA
Sbjct: 1120 RIEELE----EEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREA 1175
Query: 139 ELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTE 198
E + LE QH+A L +K+ +++ +L L+ Q LEKE E ++ +
Sbjct: 1176 EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID 1235
Query: 199 ECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQ 258
+ ++T+ + G LE+ + +++ +LK ++ Q
Sbjct: 1236 DLASNVETVSK-AKGNLEKMCRTLEDQL---------------------SELKSKEEEQQ 1273
Query: 259 ALAFVQDLVTALLNFHTYTEQRIQIFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGM 318
L + DL T QR + + +FS+ L E + V L G
Sbjct: 1274 RL--INDL----------TAQR----------GRLQTESGEFSRQLDEKEALVSQLSRGK 1311
Query: 319 LHLFESITEDTVTVLETTVKLKTFSEHL---TSYICFLRKILPYQLKSLEEECESSL-CT 374
F E+ LE +K K H + + C L + + EEE ES
Sbjct: 1312 -QAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLR------EQYEEEQESKAELQ 1364
Query: 375 SALRARNLELSQ-------DMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNV 427
AL N E++Q D + T E+ + +A + E + +S+
Sbjct: 1365 RALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTK 1424
Query: 428 GAALHGFHDVMKDISKHYSQKAAIEHE-------LPTATQKLITTN---DCILSSVVALT 477
+ D+M D+ + + AA++ + L QK T+ + +L
Sbjct: 1425 QRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLG 1484
Query: 478 NGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAAYMKSLRKPLLE 537
KI + + +LD + +L K IS L+ E + + K+ K ++ E
Sbjct: 1485 TELFKIKNAYEESLDQ-LETLKRENKNLQQEISDLT-EQIAEGGKRIHELEKIKKQVEQE 1542
Query: 538 SVPYEEALANRRILLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKEN 597
+ AL +S E EG ++Q L ++ + E + + E +L++ +
Sbjct: 1543 KCELQAALEEAE---ASLEHEEGKILRIQLELNQV---KSEVDRKIAEKDEEIDQLKRNH 1596
Query: 598 QRIADKLKNTGSAQL------VGLAQE-----NAAVSNTAGQDEATAKAVLEPIQSTSLV 646
RI + +++T A++ + L ++ N + A+A+ + ++
Sbjct: 1597 IRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGIL 1656
Query: 647 PDVESR-EDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEE 705
D + +D +++ +L QL + + ++ AE L L E+S++ +E
Sbjct: 1657 KDTQIHLDDALRSQ-----EDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQE 1711
Query: 706 MKLASQNISRLQDE---LTTTKRSYEDQLSMMSDHL 738
+ AS+ + L + L TK+ E +S M +
Sbjct: 1712 LLDASERVQLLHTQNTSLINTKKKLETDISQMQGEM 1747
Score = 68.9 bits (167), Expect = 2e-11
Identities = 164/788 (20%), Positives = 324/788 (41%), Gaps = 89/788 (11%)
Query: 3 SAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSL 62
+AEL K +KL E S+L KK + D + A ++++ + ++ L +EM L
Sbjct: 939 NAELTAKKRKLEDECSEL-------KKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 991
Query: 63 TFRNLQLAKRVELLQD--ELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENE 120
+L K + LQ+ + L + + +++K + + +++ EQ+ +DL+ +E+ +
Sbjct: 992 DETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQV---DDLEGSLEQEK 1048
Query: 121 RLHIQFFE-----------ADEQHKHVEAE---LRSRLATLETEAAQHQAVVDGLTRKYM 166
+L + A E +E E L +L E E + Q+ ++ +
Sbjct: 1049 KLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGI 1108
Query: 167 ETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKV 226
+ +K++ +A++E + +E E + R + E+ + L E++S RLEE+ + ++
Sbjct: 1109 QLQKKIKELQARIEELEEEIEAE-RASRAKAEKQRSDLSRELEEISERLEEAGGATSAQI 1167
Query: 227 PFNDTKYSQYNALNVPLHNR--RHQLKMRDIAGQALAFVQDLVTALLNFHTY-------- 276
N + +++ + L +H+ + + V +L + N
Sbjct: 1168 EMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEK 1227
Query: 277 TEQRIQIFPVDSAIDTISPLN---QKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVL 333
+E +++I + S ++T+S +K + L + S ++ EE L +T +
Sbjct: 1228 SEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQ 1287
Query: 334 ETTVKLK---TFSEHLTSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQ-DMK 389
+ + E L S + ++ Q++ L+ + E + A L+ S+ D
Sbjct: 1288 TESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCD 1347
Query: 390 KMTAVFEKLQTYIALL--ALPSTEPD-GLLRTNYSSVLTNVGAALHGFHDVMKDISKHYS 446
+ +E+ Q A L AL + RT Y T+ + K +++
Sbjct: 1348 LLREQYEEEQESKAELQRALSKANTEVAQWRTKYE---TDAIQRTEELEEAKKKLAQRL- 1403
Query: 447 QKAAIEH---------ELPTATQKLIT-TNDCILSSVVALTNGAGKIASFFSNNLDYFIA 496
+AA EH L Q+L D +L V TN A N D +A
Sbjct: 1404 -QAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLD--VERTNAACAALDKKQRNFDKILA 1460
Query: 497 SLSYGPKAASGFISPLSAECM---LQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLS 553
+ + E + K AY +SL + LE++ E + I
Sbjct: 1461 EWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ--LETLKRENKNLQQEISDL 1518
Query: 554 STESREGLAQQVQQSLEKISK-LEQEKEHWMLEAQLAKIKLEKEN---QRIADKLKNTGS 609
+ + EG +++ + LEKI K +EQEK + A+ LE E RI +L S
Sbjct: 1519 TEQIAEG-GKRIHE-LEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKS 1576
Query: 610 AQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVESREDLI--KNHYMARIVEL 667
+A+++ + Q + ++E +QST L ++ SR D I K + E+
Sbjct: 1577 EVDRKIAEKDEEID----QLKRNHIRIVESMQST-LDAEIRSRNDAIRLKKKMEGDLNEM 1631
Query: 668 TSQLQLAD---SKSVHFYAECRALSK----RLALAEKSKEALTEEMKLASQNISRLQDEL 720
QL A+ ++++ Y + + K L A +S+E L E++ + + + LQ E+
Sbjct: 1632 EIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEI 1691
Query: 721 TTTKRSYE 728
+ + E
Sbjct: 1692 EELRATLE 1699
Score = 57.0 bits (136), Expect = 6e-08
Identities = 161/826 (19%), Positives = 315/826 (38%), Gaps = 161/826 (19%)
Query: 4 AELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLT 63
A ++ ++QK+ E +K A+ + L++ +V L+ Q++ + + L ++ D L
Sbjct: 856 ATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLI 915
Query: 64 FRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDE--DLQKKIEENER 121
+QL +++ + + E E +++L+ +++ + DE +L+K I++
Sbjct: 916 KTKIQLEAKIKEVTERAEDEE----------EINAELTAKKRKLEDECSELKKDIDD--- 962
Query: 122 LHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYM---ETIEKLQNDKAK 178
L LA +E E + V LT + ETI KL +K
Sbjct: 963 ------------------LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKA 1004
Query: 179 L-EVKSQTLEK-EAKECRLRT-EECQLQLKTLHEDLSGRLEES------LSIINEKVPFN 229
L E QTL+ +A+E ++ T + +++L+ +DL G LE+ L K+
Sbjct: 1005 LQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLE-G 1063
Query: 230 DTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSA 289
D K +Q + +++ N + QL + ++ +I + S
Sbjct: 1064 DLKLAQESIMDI--ENEKQQLDEK----------------------LKKKEFEISNLQSK 1099
Query: 290 IDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSY 349
I+ L + + + E + + LEE + E + K +
Sbjct: 1100 IEDEQALGIQLQKKIKELQARIEELEEEI-------------EAERASRAKAEKQ----- 1141
Query: 350 ICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPS 409
R L +L+ + E E + + +E++ KK A F+K++ + L
Sbjct: 1142 ----RSDLSRELEEISERLEEA---GGATSAQIEMN---KKREAEFQKMRRDLEEATLQH 1191
Query: 410 TEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQ--------- 460
LR ++ + +G + V + + K S+ +L + +
Sbjct: 1192 EATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNL 1251
Query: 461 -KLITTNDCILSSVVA-----------LTNGAGKI---ASFFSNNLDY---FIASLSYGP 502
K+ T + LS + + LT G++ + FS LD ++ LS G
Sbjct: 1252 EKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGK 1311
Query: 503 KAASGFISPLSAECMLQYKKKAA---AYMKSLRKPLLESVPYEE-----ALANRRILLSS 554
+A + I L + + K K A A S L YEE A R + ++
Sbjct: 1312 QAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKAN 1371
Query: 555 TESREGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRIA------DKLKNTG 608
TE + + ++++ +LE+ K+ Q A+ +E N + A +L+N
Sbjct: 1372 TEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEV 1431
Query: 609 SAQLVGLAQENAAVSNTAGQDEATAKAVLE---PIQSTSLVPDVESRED--------LIK 657
++ + + NAA + + K + E + T + +E IK
Sbjct: 1432 EDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIK 1491
Query: 658 NHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQ 717
N Y E QL+ ++ + E L++++A K L + K Q LQ
Sbjct: 1492 NAY----EESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQ 1547
Query: 718 DELTTTKRSYEDQLSMMSDHLCSMNET-------LSKQREEIDTLK 756
L + S E + + +N+ ++++ EEID LK
Sbjct: 1548 AALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLK 1593
Score = 40.8 bits (94), Expect = 0.005
Identities = 49/247 (19%), Positives = 108/247 (43%), Gaps = 36/247 (14%)
Query: 6 LQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFR 65
LQ + ++L + ++ ++ ++D L Q + +KL+ ++
Sbjct: 1687 LQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDIS----- 1741
Query: 66 NLQLAKRVELLQDELALSEPRGKKN-----------KKSGESSSQLSQEQKSVFD--EDL 112
Q+ +E + E +E + KK KK ++S+ L + +K++ +DL
Sbjct: 1742 --QMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDL 1799
Query: 113 QKKIEENERLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGL----------- 161
Q +++E E+L ++ +Q + +EA +R +E+E ++ V GL
Sbjct: 1800 QLRLDEAEQLALK--GGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELT 1857
Query: 162 --TRKYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESL 219
T + + I +LQ+ KL+ K ++ +++A+E ++ + + L +L EE
Sbjct: 1858 YQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELE-EAEERA 1916
Query: 220 SIINEKV 226
I +V
Sbjct: 1917 DIAESQV 1923
Score = 32.3 bits (72), Expect = 1.7
Identities = 28/124 (22%), Positives = 54/124 (43%), Gaps = 3/124 (2%)
Query: 628 QDEATAKAVLEPIQSTSLVPDVESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRA 687
++ AT K + I+ L R++L + M +++ + LQL A+
Sbjct: 853 KEMATMKEEFQKIKD-ELAKSEAKRKELEEK--MVTLLKEKNDLQLQVQAEAEGLADAEE 909
Query: 688 LSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSK 747
+L + EA +E+ +++ + ELT KR ED+ S + + + TL+K
Sbjct: 910 RCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAK 969
Query: 748 QREE 751
+E
Sbjct: 970 VEKE 973
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 71.6 bits (174), Expect = 3e-12
Identities = 161/796 (20%), Positives = 303/796 (38%), Gaps = 119/796 (14%)
Query: 19 KLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQD 78
KL ++ ++ ++D + + L E+LK KD L L ++ QL K+++ LQ
Sbjct: 1054 KLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQA 1113
Query: 79 ELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEADEQHKHVEA 138
+ E + + + +L + +E ++ E +Q E +K EA
Sbjct: 1114 RIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQI----EMNKKREA 1169
Query: 139 ELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTE 198
E + LE QH+A L +K+ +++ +L L+ Q LEKE E +L
Sbjct: 1170 EFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL- 1228
Query: 199 ECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQ 258
+D++ +E+ II K + + +N + R A +
Sbjct: 1229 ----------DDVTSNMEQ---IIKAKANLEKMCRTLEDQMN----------EHRSKAEE 1265
Query: 259 ALAFVQDLVTALLNFHTYTEQRIQIFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGM 318
V DL T QR + + N + S+ L E + + L G
Sbjct: 1266 TQRSVNDL----------TSQRAK----------LQTENGELSRQLDEKEALISQLTRGK 1305
Query: 319 LHLFESITEDTVTVLETTVKLKTFSEHL---TSYICFLRKILPYQLKSLEEECESSL-CT 374
L + + ED LE VK K H + C L + + EEE E+
Sbjct: 1306 LTYTQQL-EDLKRQLEEEVKAKNALAHALQSARHDCDLLR------EQYEEETEAKAELQ 1358
Query: 375 SALRARNLELSQ-------DMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNV 427
L N E++Q D + T E+ + +A + E + SS+
Sbjct: 1359 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTK 1418
Query: 428 GAALHGFHDVMKDISKHYSQKAAIEHE-------LPTATQKLITTNDCILSS---VVALT 477
+ D+M D+ + + AA++ + L QK + + SS +L+
Sbjct: 1419 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLS 1478
Query: 478 NGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAEC---------MLQYKKKAAAYM 528
K+ + + +L++ + + K IS L+ + + + +K+ A
Sbjct: 1479 TELFKLKNAYEESLEH-LETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEK 1537
Query: 529 KSLRKPLLE---SVPYEEALANRRILLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLE 585
L+ L E S+ +EE +IL + E + A+ ++ EK ++EQ K + +
Sbjct: 1538 MELQSALEEAEASLEHEEG----KILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRV 1593
Query: 586 AQLAKIKLEKE----NQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQ 641
+ L+ E N+ + K K G + + +A + A + + K++ ++
Sbjct: 1594 VDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHA--NRMAAEAQKQVKSLQSLLK 1651
Query: 642 STSLVPD--VESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLA------ 693
T + D V + +DL +N IVE + L A+ + + E S++LA
Sbjct: 1652 DTQIQLDDAVRANDDLKEN---IAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIE 1708
Query: 694 ------LAEKSKEALTEEMKLASQNISRLQ---DELTTTKRSYEDQLSMMSDHLCSMNET 744
L +L + K ++S+LQ +E R+ E++ M E
Sbjct: 1709 TSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEE 1768
Query: 745 LSKQREEIDTLKMSSK 760
L K+++ L+ K
Sbjct: 1769 LKKEQDTSAHLERMKK 1784
Score = 62.0 bits (149), Expect = 2e-09
Identities = 148/754 (19%), Positives = 287/754 (38%), Gaps = 121/754 (16%)
Query: 41 LKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQL 100
LKE L+ + ++L+++M SL L +V+ QD LA +E E QL
Sbjct: 859 LKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAE----------ERCDQL 908
Query: 101 SQEQKSVFDEDLQKKIEE-NERLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVD 159
+ + L+ K++E NERL E + + AEL ++ LE E ++ + +D
Sbjct: 909 IKNK-----IQLEAKVKEMNERL--------EDEEEMNAELTAKKRKLEDECSELKRDID 955
Query: 160 GLTRKYMETIEKLQNDKAKLEVKSQTLEKE-----------AKECRLRTEECQLQLKTL- 207
L T+ K++ +K E K + L +E KE + E Q L L
Sbjct: 956 DLEL----TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQ 1011
Query: 208 -HEDLSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDL 266
ED L ++ + ++V + Q + + L + +L+ L Q+
Sbjct: 1012 AEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLE------GDLKLTQES 1065
Query: 267 VTALLNFHTYTEQRI-----QIFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHL 321
+ L N ++R+ ++ +++ I+ L + + L E + + LEE +
Sbjct: 1066 IMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL--- 1122
Query: 322 FESITEDTVTVLETTVKLKTFSEHLTSYICFLRKILPYQLKSLEEECESSLCTSALRARN 381
E T + K LR L +L+ + E E + ++++
Sbjct: 1123 ----------EAERTARAKVEK---------LRSDLSRELEEISERLEEAGGATSVQ--- 1160
Query: 382 LELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDI 441
+E++ KK A F+K++ + L LR ++ + +G + V + +
Sbjct: 1161 IEMN---KKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKL 1217
Query: 442 SKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNNLDYFIASLSYG 501
K +K+ + EL T + ++ K+ + ++ +
Sbjct: 1218 EK---EKSEFKLELDDVTSN--------MEQIIKAKANLEKMCRTLEDQMNEHRSKAEET 1266
Query: 502 PKAASGFISPL------SAECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLSST 555
++ + S + E Q +K A + R L + E+ +R L
Sbjct: 1267 QRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDL---KRQLEEEV 1323
Query: 556 ESREGLAQQVQQSLEKISKL-EQEKEHWMLEAQLAKIKLEKENQRIADKLKNTGSAQLVG 614
+++ LA +Q + L EQ +E +A+L ++ L K N +A
Sbjct: 1324 KAKNALAHALQSARHDCDLLREQYEEETEAKAELQRV-LSKANSEVAQWRTK-------- 1374
Query: 615 LAQENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVE---SREDLIKNHYMARIVELTSQL 671
E A+ T +EA K ++ V V S + K+ I +L +
Sbjct: 1375 --YETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDV 1432
Query: 672 QLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQL 731
+ +++ + + R K LA ++ E E++ + + L EL K +YE+ L
Sbjct: 1433 ERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESL 1492
Query: 732 SMMSDHLCSMNETLSKQREEIDTL--KMSSKGNS 763
+HL + +EEI L ++ S G +
Sbjct: 1493 ----EHLETFKRENKNLQEEISDLTEQLGSSGKT 1522
Score = 52.0 bits (123), Expect = 2e-06
Identities = 162/809 (20%), Positives = 326/809 (40%), Gaps = 98/809 (12%)
Query: 11 QKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLA 70
+K E+ K+R L++ + +A +AAL+ K S+ +L +++D+L +L
Sbjct: 1165 KKREAEFQKMRRD---LEEATLQHEATAAALR---KKHADSVAELGEQIDNLQRVKQKLE 1218
Query: 71 KR---VELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFF 127
K +L D++ + + K K + E + ++Q + + + K EE +R
Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMN----EHRSKAEETQR------ 1268
Query: 128 EADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLE 187
+ A+L++ L + + +A++ LTR + ++L++ K +LE + +
Sbjct: 1269 -SVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKN 1327
Query: 188 KEAKECRLRTEECQLQLKTLHEDLSGR--LEESLSIINEKVPFNDTKYSQYNALNVPLHN 245
A + +C L + E+ + L+ LS N +V TKY + +A+
Sbjct: 1328 ALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY-ETDAIQRTEEL 1386
Query: 246 RRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAID------TISPLNQK 299
+ K+ +A V + V A + T+ R+Q D +D + L++K
Sbjct: 1387 EEAKKKLAQRLQEAEEAV-EAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKK 1445
Query: 300 FSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLK-TFSEHLTSYICFLR--KI 356
+ A + + EE L ES ++ ++ KLK + E L F R K
Sbjct: 1446 QRNFDKILAEWKQKYEESQSEL-ESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKN 1504
Query: 357 LPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLL 416
L ++ L E+ SS T EL + K++ A EK++ AL E + L
Sbjct: 1505 LQEEISDLTEQLGSSGKTIH------ELEKVRKQLEA--EKMELQSAL-----EEAEASL 1551
Query: 417 RTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVVAL 476
+L A F+ + +I + ++K + E+ A + + D + +S+ A
Sbjct: 1552 EHEEGKIL----RAQLEFNQIKAEIERKLAEK---DEEMEQAKRNHLRVVDSLQTSLDAE 1604
Query: 477 T---NGAGKIASFFSNNLDYFIASLSYGPK-AASGFISPLSAECMLQYKKKAAAYMKSLR 532
T N A ++ +L+ LS+ + AA S + +L+ +
Sbjct: 1605 TRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRAN 1664
Query: 533 KPLLESVPYEEALAN---------RRILLSSTESREGLAQQVQQSLEKISKLEQE----- 578
L E++ E N R ++ + SR+ Q++ ++ E++ L +
Sbjct: 1665 DDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLI 1724
Query: 579 KEHWMLEAQLAKIKLEKENQ----RIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAK 634
+ ++A L++++ E E R A++ +A+E +T+ E K
Sbjct: 1725 NQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKK 1784
Query: 635 AVLEPIQSTSLVPDVESREDLIK------NHYMARIVELTSQLQLADSKSVHFYAECRAL 688
+ + I+ D E+ + +K AR+ EL ++L+ ++ R
Sbjct: 1785 NMEQTIKDLQHRLD-EAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKS 1843
Query: 689 SKRLALAEKSKEALTEEMKLASQNISRLQ---DELTTTKRSYEDQLSMMSDHLCSMNETL 745
+R+ + LT + + +N+ RLQ D+L ++Y+ Q + +
Sbjct: 1844 ERRI-------KELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKF 1896
Query: 746 SKQREEIDTLK-----MSSKGNSKKNKSR 769
K + E+D + S+ N + KSR
Sbjct: 1897 RKVQHELDEAEERADIAESQVNKLRAKSR 1925
Score = 42.7 bits (99), Expect = 0.001
Identities = 50/236 (21%), Positives = 95/236 (40%), Gaps = 16/236 (6%)
Query: 533 KPLLESVPYEEALANRRI----LLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEAQL 588
KPLL+S E+ +A+ + L + E E ++++ EK+ L QEK L+ Q
Sbjct: 837 KPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELE---EKMVSLLQEKNDLQLQVQA 893
Query: 589 AKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVPD 648
+ L +R +KN + E TAK + + L D
Sbjct: 894 EQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRD 953
Query: 649 VESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKL 708
++ E + ++ + ++K + E L + +A K K+AL E +
Sbjct: 954 IDDLE--------LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1005
Query: 709 ASQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSKQREEIDTLKMSSKGNSK 764
A ++ +D++ T ++ + +L D L E K R +++ K +G+ K
Sbjct: 1006 ALDDLQAEEDKVNTLTKA-KVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1060
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 68.2 bits (165), Expect = 3e-11
Identities = 136/736 (18%), Positives = 287/736 (38%), Gaps = 52/736 (7%)
Query: 13 LAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKR 72
L + KL ++ ++ ++D + + L E+LK KD +LQ +++ LQ K+
Sbjct: 1049 LERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKK 1108
Query: 73 VELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEADEQ 132
++ LQ + E + ++ ++ +++Q+S + +L++ E E E
Sbjct: 1109 IKELQARIEELE----EEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIEL 1164
Query: 133 HKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEAKE 192
+K EAE LE QH+A+V L +K+ +++ +L L+ Q LEKE E
Sbjct: 1165 NKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSE 1224
Query: 193 CRLRTEECQLQLKTLH------EDLSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNR 246
+L ++ ++++ E + LE+ LS K S+ L
Sbjct: 1225 FKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTE 1284
Query: 247 RHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQ-RIQIFPVDSAIDTISPLNQKFSQYLH 305
+L + + + V L + F TE+ + Q+ + A + ++ Q
Sbjct: 1285 AGELSRQ--LEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCD 1342
Query: 306 ENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSYICFLRKILPYQLKSLE 365
+EG L ++++ V + K +T + T + +K L +L+ E
Sbjct: 1343 LLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSE 1402
Query: 366 EECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNYSSVLT 425
E+ E A+ A+ L + +++ E L + + D R N+ VL
Sbjct: 1403 EQVE------AVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQR-NFDKVLA 1455
Query: 426 NVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIAS 485
K +++ E E + ++T L + +
Sbjct: 1456 E---------------WKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVK 1500
Query: 486 FFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAAYMKSLRKPLLESVPYEEAL 545
+ NL+ IA L+ I L + Q + + A +L + E+ E
Sbjct: 1501 RENKNLEQEIADLTEQIAENGKTIHELE-KSRKQIELEKADIQLALEE--AEAALEHEEA 1557
Query: 546 ANRRILLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRIADKLK 605
RI L T+ + + +++ + E+I +L++ + +E + + E ++ A +LK
Sbjct: 1558 KILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQR-TVETMQSALDAEVRSRNEAIRLK 1616
Query: 606 NTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVESREDLIKNHYMARIV 665
L + + + + A + ++V ++ T L D D ++
Sbjct: 1617 KKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLD-----DALRGQ-----E 1666
Query: 666 ELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDELTT--- 722
+L QL + + ++ AE L L E++++ +E+ +++ + L + T+
Sbjct: 1667 DLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIH 1726
Query: 723 TKRSYEDQLSMMSDHL 738
TK+ E L + +
Sbjct: 1727 TKKKLETDLMQLQSEV 1742
Score = 60.1 bits (144), Expect = 8e-09
Identities = 155/847 (18%), Positives = 323/847 (38%), Gaps = 186/847 (21%)
Query: 5 ELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAAL---KEQLKMKDQSLRKLQQEMDS 61
EL+ K L QE + L+ Q Q + ++D + L K QL+ K + + + ++ +
Sbjct: 873 ELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEE 932
Query: 62 LTFRNLQLAKRVELLQDE----------LALSEPRGKKNKKSGESSSQLSQEQKSVFDED 111
+ N +L + L+DE L L+ + +K K + E+ + E+ S DE
Sbjct: 933 I---NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDET 989
Query: 112 LQKKIEENERLH------IQFFEADEQH----KHVEAELRSRLATLETEAAQHQAV---- 157
+ K E + L + +A+E +++L ++ LE+ Q + +
Sbjct: 990 IAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDL 1049
Query: 158 ------VDGLTRKYMETIEKLQNDKAKLEVK-----------------SQTL----EKEA 190
++G + E+I L+NDK +L+ + QTL +K+
Sbjct: 1050 ERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKI 1109
Query: 191 KECRLRTEECQLQLKTLH-----------------EDLSGRLEESLSIINEKVPFNDTKY 233
KE + R EE + +++ E+LS RLEE+ + + ++ N +
Sbjct: 1110 KELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKRE 1169
Query: 234 SQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAIDTI 293
+++ LK+R +A + +V AL H + + + ID +
Sbjct: 1170 AEF-------------LKLRRDLEEATLQHEAMVAALRKKHADS-----VAELGEQIDNL 1211
Query: 294 SPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSYICFL 353
+ QK + E F+ +D + +E+ K K E IC
Sbjct: 1212 QRVKQKLEKEKSE---------------FKLEIDDLSSSMESVSKSKANLEK----IC-- 1250
Query: 354 RKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPD 413
++LE++ S R +N E+ + + ++T +LQT L+ E +
Sbjct: 1251 --------RTLEDQ------LSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKE 1296
Query: 414 GLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCILSSV 473
S+++ + + F +++ + ++ ++ L A Q + +DC L
Sbjct: 1297 --------SIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQS--SRHDCDLLRE 1346
Query: 474 VALTNGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAEC---MLQYKKKAAAYMKS 530
GK A L A+ ++ + +Q ++ K
Sbjct: 1347 QYEEEQEGK-------------AELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKK 1393
Query: 531 LRKPLLESVPYEEALANRRILLSSTESR-----EGLAQQVQQSLEKISKLEQEKEH---- 581
L + L +S EA+ + L T+ R E L V+++ + L++++ +
Sbjct: 1394 LAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKV 1453
Query: 582 ---WMLEAQLAKIKLE---KENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKA 635
W + + ++ +LE KE++ ++ +L +A L Q ++ A
Sbjct: 1454 LAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADL 1513
Query: 636 VLEPIQSTSLVPDVESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALA 695
+ ++ + ++E K+ + + QL L ++++ + E + L +L L
Sbjct: 1514 TEQIAENGKTIHELE------KSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELT 1567
Query: 696 EKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSKQREEIDTL 755
+ E + I+ +E+ KR+Y+ + M L + + R E L
Sbjct: 1568 QVKSE--------IDRKIAEKDEEIEQLKRNYQRTVETMQSAL----DAEVRSRNEAIRL 1615
Query: 756 KMSSKGN 762
K +G+
Sbjct: 1616 KKKMEGD 1622
Score = 54.7 bits (130), Expect = 3e-07
Identities = 168/802 (20%), Positives = 317/802 (39%), Gaps = 88/802 (10%)
Query: 11 QKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLA 70
+K E+ KLR L++ + +A AAL+ K S+ +L +++D+L +L
Sbjct: 1166 KKREAEFLKLRRD---LEEATLQHEAMVAALR---KKHADSVAELGEQIDNLQRVKQKLE 1219
Query: 71 KR---VELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFF 127
K +L D+L+ S K+K + E + ++Q L + +NE +
Sbjct: 1220 KEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQ-------LSEARGKNEEIQRSLS 1272
Query: 128 EADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLE 187
E Q ++ L++ L + + +++V L+R ++ + K +LE +++
Sbjct: 1273 ELTTQ----KSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKN 1328
Query: 188 KEAKECRLRTEECQLQLKTLHEDLSGR--LEESLSIINEKVPFNDTKYSQYNALN--VPL 243
A + +C L + E+ G+ L+ +LS N +V TKY + +A+ L
Sbjct: 1329 ALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKY-ETDAIQRTEEL 1387
Query: 244 HNRRHQL--KMRDIAGQALAFVQDLVTALLNFHTYTEQRIQ------IFPVDSAIDTISP 295
+ +L +++D Q A V A T+QR+Q + V+ A +
Sbjct: 1388 EEAKKKLAQRLQDSEEQVEA-----VNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAA 1442
Query: 296 LNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSYICFLRK 355
L++K + A + EE L S+ E E KLK E + +++
Sbjct: 1443 LDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTEL-FKLKNAYEEALDQLETVKR 1501
Query: 356 ILPYQLKSLEEECESSLCTSALRARNL-ELSQDMKKMTAVFEKLQTYIALLALPSTEPDG 414
+ K+LE+E A + + EL + K++ EK +AL E +
Sbjct: 1502 ----ENKNLEQEIADLTEQIAENGKTIHELEKSRKQIE--LEKADIQLAL-----EEAEA 1550
Query: 415 LLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVV 474
L + +L + L V +I + ++K +L Q+ + T L + V
Sbjct: 1551 ALEHEEAKIL-RIQLELT---QVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEV 1606
Query: 475 ALTNGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAAYMKSLR-- 532
N A ++ +L+ LS+ + A+ + L + Q K +LR
Sbjct: 1607 RSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRS-VQGQLKDTQLHLDDALRGQ 1665
Query: 533 KPLLESVPYEEALANR--------RILLSSTESREGLAQQ-VQQSLEKISKLEQEKEHWM 583
+ L E + E AN R L TE LA+Q + S E++ L + +
Sbjct: 1666 EDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLI 1725
Query: 584 -----LEAQLAKIKLEKENQ----RIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAK 634
LE L +++ E E+ R A++ +A+E +T+ E K
Sbjct: 1726 HTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKK 1785
Query: 635 AVLEPIQSTSLVPDVESREDLIKN------HYMARIVELTSQLQLADSKSVHFYAECRAL 688
+ + ++ D E+ + +K RI EL +L+ K+ R
Sbjct: 1786 NLEQTVKDLQHRLD-EAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKY 1844
Query: 689 SKRLA-LAEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSK 747
+R+ L +S+E ++L + +LQ ++ + KR E+ + HL +
Sbjct: 1845 ERRVKELTYQSEEDRKNVLRLQDL-VDKLQVKVKSYKRQAEEADEQANAHLTKFRKA--- 1900
Query: 748 QREEIDTLKMSSKGNSKKNKSR 769
Q E + + + S+ NK R
Sbjct: 1901 QHELEEAEERADIAESQVNKLR 1922
Score = 42.7 bits (99), Expect = 0.001
Identities = 49/241 (20%), Positives = 99/241 (41%), Gaps = 28/241 (11%)
Query: 551 LLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKEN-------QRIADK 603
L S E + L Q Q+ ++++ +E E + + + K EK+ + ++++
Sbjct: 1091 LQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSER 1150
Query: 604 LKNTG---SAQL-VGLAQENAAVSNTAGQDEAT--------------AKAVLEPIQSTSL 645
L+ G S Q+ + +E + +EAT A +V E +
Sbjct: 1151 LEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDN 1210
Query: 646 VPDVESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEE 705
+ V+ + + K+ + I +L+S ++ + CR L +L+ A E +
Sbjct: 1211 LQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRS 1270
Query: 706 MKLASQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSKQREEIDTLKMSSKGNSKK 765
+ + SRLQ E R E++ S++S L + ++Q EE+ + + N K
Sbjct: 1271 LSELTTQKSRLQTEAGELSRQLEEKESIVS-QLSRSKQAFTQQTEELK--RQLEEENKAK 1327
Query: 766 N 766
N
Sbjct: 1328 N 1328
Score = 42.0 bits (97), Expect = 0.002
Identities = 55/257 (21%), Positives = 107/257 (41%), Gaps = 37/257 (14%)
Query: 6 LQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFR 65
LQG+ + L + + + L K + A K + + L +E SL+
Sbjct: 1422 LQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTE 1481
Query: 66 NLQLAKRVELLQDELALSEPRGKK-NKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHI 124
+L E D+L + K ++ + + Q+++ K++ + + +K E E+ I
Sbjct: 1482 LFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADI 1541
Query: 125 QFF--EADEQHKHVEA-------ELRSRLATLETEAAQHQAVVDGLTRKYMETIE----- 170
Q EA+ +H EA EL + ++ + A+ ++ L R Y T+E
Sbjct: 1542 QLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSA 1601
Query: 171 ----------------KLQNDKAKLEVKSQTLEKEAKEC--RLRTEECQLQLKTLHED-- 210
K++ D ++E++ ++A E LR+ + QL+ LH D
Sbjct: 1602 LDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDA 1661
Query: 211 LSGR--LEESLSIINEK 225
L G+ L+E L+I+ +
Sbjct: 1662 LRGQEDLKEQLAIVERR 1678
Score = 30.4 bits (67), Expect = 6.5
Identities = 22/101 (21%), Positives = 45/101 (44%)
Query: 50 QSLRKLQQEMDSLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFD 109
+ LRK ++ + LT+++ + K V LQD + + + K K+ E + + + + F
Sbjct: 1839 KGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFR 1898
Query: 110 EDLQKKIEENERLHIQFFEADEQHKHVEAELRSRLATLETE 150
+ + E ER I + ++ SR+ E+E
Sbjct: 1899 KAQHELEEAEERADIAESQVNKLRAKTRDFTSSRMVVHESE 1939
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 68.2 bits (165), Expect = 3e-11
Identities = 141/738 (19%), Positives = 294/738 (39%), Gaps = 68/738 (9%)
Query: 19 KLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQD 78
KL ++ ++ +D + + L E+L+ K+ + L +++ +QL K+++ LQ
Sbjct: 1057 KLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQA 1116
Query: 79 ELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEADEQHKHVEA 138
+ E G++ + S ++ +++Q+S +L++ E E E +K EA
Sbjct: 1117 RI---EELGEEIEAERASRAK-AEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREA 1172
Query: 139 ELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTE 198
E + LE QH+A+V L +K+ +++ +L L+ Q LEKE E ++ T+
Sbjct: 1173 EFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETD 1232
Query: 199 ECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQ 258
+ + + + G LE+ + ++V TK + L L +R +L+ AG+
Sbjct: 1233 DLSSNAEAISK-AKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTE--AGE 1289
Query: 259 ALAFVQD---LVTALLNFHTYTEQRI-----QIFPVDSAIDTISPLNQKFSQYLHENASY 310
+ + LV+ L + Q+I Q+ A + ++ Q
Sbjct: 1290 YSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQ 1349
Query: 311 VRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSYICFLRKILPYQLKSLEEECES 370
+EG L ++++ V + K +T + T + +K L +L+ EE E
Sbjct: 1350 YEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVE- 1408
Query: 371 SLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNVGAA 430
A+ A+ L + +++ E L + R+N + +
Sbjct: 1409 -----AVNAKCASLEKTKQRLQNEVEDLMLDVE-------------RSN--AACAALDKK 1448
Query: 431 LHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNN 490
F V+ + + Y + A EL A+QK +L+ K+ + + +
Sbjct: 1449 QRNFDKVLSEWKQKYEETQA---EL-EASQK----------ESRSLSTELFKVKNVYEES 1494
Query: 491 LDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRI 550
LD + +L K IS L+ E + + K+ K ++ E + AL
Sbjct: 1495 LDQ-LETLRRENKNLQQEISDLT-EQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAE- 1551
Query: 551 LLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRIADKLKNTGSA 610
+S E EG ++Q L ++ + E + + E +L++ + R+ + +++T A
Sbjct: 1552 --ASLEHEEGKILRIQLELNQV---KSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDA 1606
Query: 611 QLVGLAQENAAVSNTAG-------QDEATAKAVLEPIQSTSLVPDVESREDLIKNHYMAR 663
++ G Q + E +++ + L + +
Sbjct: 1607 EIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRG 1666
Query: 664 IVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDE---L 720
+L QL + + ++ AE L L E+S++ +E+ AS+ + L + L
Sbjct: 1667 QEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSL 1726
Query: 721 TTTKRSYEDQLSMMSDHL 738
TK+ E+ +S + +
Sbjct: 1727 INTKKKLENDVSQLQSEV 1744
Score = 57.8 bits (138), Expect = 4e-08
Identities = 163/793 (20%), Positives = 328/793 (41%), Gaps = 115/793 (14%)
Query: 3 SAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSL 62
+AEL K +KL E S+L KK + D + A ++++ + ++ L +EM L
Sbjct: 936 NAELTAKKRKLEDECSEL-------KKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 988
Query: 63 TFRNLQLAKRVELLQD--ELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENE 120
+L+K + LQ+ + L + + +++K + + ++ EQ+ +DL+ +E+ +
Sbjct: 989 DETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQV---DDLEGSLEQEK 1045
Query: 121 RLHIQFFEADEQHKHVEAELR-SRLATLETEAAQHQAVVDGLTRKYME---TIEKLQNDK 176
+L + + + + +E +L+ ++ +T++ E + Q + + L +K E I K+++++
Sbjct: 1046 KLRM---DLERAKRKLEGDLKLAQESTMDMENDKQQ-LDEKLEKKEFEISNLISKIEDEQ 1101
Query: 177 A---KLEVKSQTLEKEAKE----------CRLRTEECQLQLKTLHEDLSGRLEESLSIIN 223
A +L+ K + L+ +E R + E+ + L E++S RLEE+ +
Sbjct: 1102 AVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATS 1161
Query: 224 EKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQI 283
+V N + +++ L RD+ L + +V AL H + +
Sbjct: 1162 AQVELNKKREAEFQKLR------------RDLEEATLQH-EAMVAALRKKHADS-----M 1203
Query: 284 FPVDSAIDTISPLNQKFSQY----------LHENASYVRPLEEGMLHLFESITEDTVTVL 333
+ ID + + QK + L NA + + + + S+ ED V+ L
Sbjct: 1204 AELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSL-EDQVSEL 1262
Query: 334 ET-TVKLKTFSEHLTSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMT 392
+T + + LT+ L+ + L+E + +L + R++ Q +
Sbjct: 1263 KTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDE--KDALVSQLSRSKQASTQQIEELKH 1320
Query: 393 AVFEKLQTYIALL-ALPSTEPD-GLLRTNYSSVLTNVGAALHGFHDVMKDI----SKHYS 446
+ E+ + AL AL S+ D LLR Y ++ +K+ +
Sbjct: 1321 QLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYET 1380
Query: 447 QKAAIEHELPTATQKL---ITTNDCILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPK 503
EL A +KL + + + +V A K N ++ + +
Sbjct: 1381 DAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNA 1440
Query: 504 AASGF------ISPLSAECMLQYKKKAAAYMKSLRKPLLESVP-------YEEAL----- 545
A + + +E +Y++ A S ++ S YEE+L
Sbjct: 1441 ACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLET 1500
Query: 546 ---ANRRILLSSTESREGLAQQVQQ--SLEKISK-LEQEKEHWMLEAQLAKIKLEKEN-- 597
N+ + ++ E +A+ +Q LEKI K +EQEK + A+ LE E
Sbjct: 1501 LRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGK 1560
Query: 598 -QRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVESREDL- 655
RI +L S +A+++ + Q + V+E +QST L ++ SR D
Sbjct: 1561 ILRIQLELNQVKSEVDRKIAEKDEEID----QLKRNHTRVVETMQST-LDAEIRSRNDAL 1615
Query: 656 -IKNHYMARIVELTSQLQLAD---SKSVHFYAECRALSKRLAL----AEKSKEALTEEMK 707
+K + E+ QL A+ ++S+ Y + + K L A + +E L E++
Sbjct: 1616 RVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLA 1675
Query: 708 LASQNISRLQDEL 720
+ + + LQ E+
Sbjct: 1676 IVERRANLLQAEI 1688
Score = 35.0 bits (79), Expect = 0.26
Identities = 31/106 (29%), Positives = 53/106 (50%), Gaps = 8/106 (7%)
Query: 15 QEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVE 74
++ KL A+ + L+ V +EQ +A E +K LRK ++ + LT++ + K V
Sbjct: 1813 KQIQKLEARVRELEGEVENEQKRNA---EAVK----GLRKHERRVKELTYQTEEDRKNVL 1865
Query: 75 LLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENE 120
LQD + + + K K+ E + + S S F LQ ++EE E
Sbjct: 1866 RLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKF-RKLQHELEEAE 1910
Score = 31.6 bits (70), Expect = 2.9
Identities = 21/91 (23%), Positives = 40/91 (43%)
Query: 661 MARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDEL 720
M +++ + LQL A+ ++L + EA +E+ ++ + EL
Sbjct: 880 MVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAEL 939
Query: 721 TTTKRSYEDQLSMMSDHLCSMNETLSKQREE 751
T KR ED+ S + + + TL+K +E
Sbjct: 940 TAKKRKLEDECSELKKDIDDLELTLAKVEKE 970
Score = 30.8 bits (68), Expect = 5.0
Identities = 38/196 (19%), Positives = 86/196 (43%), Gaps = 8/196 (4%)
Query: 39 AALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSS 98
+ L +++ ++ +LR ++ L +QL L + L R +N + +
Sbjct: 1602 STLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESL-----RNYRNTQGILKET 1656
Query: 99 QLSQEQKSVFDEDLQKKIEENER-LHIQFFEADEQHKHVEAELRSR-LATLET-EAAQHQ 155
QL + EDL++++ ER ++ E +E +E RSR +A E +A++
Sbjct: 1657 QLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERV 1716
Query: 156 AVVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRL 215
++ + T +KL+ND ++L+ + + + +E++ + ++ + E+L
Sbjct: 1717 QLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQ 1776
Query: 216 EESLSIINEKVPFNDT 231
+ S + K T
Sbjct: 1777 DTSAHLERMKKNLEQT 1792
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 66.6 bits (161), Expect = 8e-11
Identities = 156/805 (19%), Positives = 309/805 (38%), Gaps = 104/805 (12%)
Query: 11 QKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKL-----QQEMDSLTFR 65
QKL ++L +NQ L + ++ ++ + L+E+ + S + + Q+++D +
Sbjct: 291 QKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQ 350
Query: 66 NLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLS---QEQKSVFDEDLQKKIEENERL 122
+ A L + + LSE +G+ +K E S++ Q K+ F + LQ++ EE E+
Sbjct: 351 SRLSASETSLHRIHVELSE-KGEATQKLKEELSEVETKYQHLKAEF-KQLQQQREEKEQH 408
Query: 123 HIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVK 182
+Q Q L S+L E + + + + E + + A L++K
Sbjct: 409 GLQLQSEINQ-------LHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLK 461
Query: 183 SQTLEKEAKECRLRTEECQLQL----------KTLHEDLSGRLEES---LSIINEKVPFN 229
LE++ KE + E Q QL + L + + +L E+ L + ++
Sbjct: 462 LSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDK 521
Query: 230 DTKYSQYNAL------NVP-LHNRRHQLKMRDIAGQALAFVQDLVTALLN-----FHTYT 277
D K AL N+ L R L + AG+ TA+LN HT
Sbjct: 522 DQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEG-------ETAVLNQLQEKNHTLQ 574
Query: 278 EQRIQIF-PVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETT 336
EQ Q+ + + ++ + + E +++R ++ +L L S+ E + E+
Sbjct: 575 EQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESK 634
Query: 337 VKLKTFSEHL---TSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTA 393
K+ + T + Q L+ +++ +AL+ + EL++ ++
Sbjct: 635 EKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTA--QNALQDKQQELNKITTQLDQ 692
Query: 394 VFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEH 453
V KLQ + + S L +K+ + Y
Sbjct: 693 VTAKLQD----------------KQEHCSQL----------ESHLKEYKEKYLSLEQKTE 726
Query: 454 ELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLS 513
EL +KL + + +S + + +L+ LS + +S S
Sbjct: 727 ELEGQIKKLEADSLEVKASKEQALQDLQQQRQ-LNTDLELRATELSKQLEMEKEIVS--S 783
Query: 514 AECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLSSTE--SREGLAQQVQQSLEK 571
LQ K +A ++S+++ L + ++ L LS E L ++Q ++ +
Sbjct: 784 TRLDLQKKSEA---LESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTE 840
Query: 572 ISKLEQEKEHWMLEAQLAKIKLEKENQRIADKLKNT----------GSAQLVGLAQENAA 621
+ K++ EKE M E K KL K ++D LKN+ G A ++ L +
Sbjct: 841 LQKVKMEKEALMTELSTVKDKLSK----VSDSLKNSKSEFEKENQKGKAAILDLEKTCKE 896
Query: 622 VSNTAG-QDEATAKAVLEPIQSTSLVPDVESREDLIKNHYMARIVELTSQLQLADSKSVH 680
+ + Q E T K E +S + + L N ++++ + L+ + +
Sbjct: 897 LKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQ 956
Query: 681 FYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMSDHLCS 740
L + +K EAL E+K+A + L+++L +L+ + +
Sbjct: 957 LQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISV 1016
Query: 741 MNETLSKQREEIDTLKMSSKGNSKK 765
+ K +E L+ G +
Sbjct: 1017 LQNNYEKSQETFKQLQSDFYGRESE 1041
Score = 52.4 bits (124), Expect = 2e-06
Identities = 55/254 (21%), Positives = 115/254 (45%), Gaps = 25/254 (9%)
Query: 4 AELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMD--- 60
++L+ ++ ++Y L + + L+ + +A+S +K K+Q+L+ LQQ+
Sbjct: 705 SQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKAS---KEQALQDLQQQRQLNT 761
Query: 61 SLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKI---E 117
L R +L+K++E+ +K SS++L ++KS E +++K+ E
Sbjct: 762 DLELRATELSKQLEM---------------EKEIVSSTRLDLQKKSEALESIKQKLTKQE 806
Query: 118 ENERLHIQFFEADEQHKHVE-AELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDK 176
E +++ Q FE Q ++ EL +R+ T TE + + + L + +KL
Sbjct: 807 EEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVS 866
Query: 177 AKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQY 236
L+ EKE ++ + + + K L L ++E +L E + +
Sbjct: 867 DSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEAS 926
Query: 237 NALNVPLHNRRHQL 250
+ L + L++ + QL
Sbjct: 927 HQLKLELNSMQEQL 940
Score = 51.6 bits (122), Expect = 3e-06
Identities = 165/787 (20%), Positives = 323/787 (41%), Gaps = 89/787 (11%)
Query: 20 LRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSL---TFRNLQ-LAKRVEL 75
LR + Q L+ + +E+ S LK++L+ K Q L++ + + D L + LQ L +++E
Sbjct: 88 LRQEVQDLQASLKEEKWYSEELKKELE-KYQGLQQQEAKPDGLVTDSSAELQSLEQQLEE 146
Query: 76 LQDE-LALSEPRGKKNKKSGESSSQLSQEQKSVFDED--LQKKIEEN-ERLHIQFFEADE 131
Q E + + + +K+ + +++++ + KS +DE+ L++ E+ RL + +
Sbjct: 147 AQTENFNIKQMKDLFEQKAAQLATEIA-DIKSKYDEERSLREAAEQKVTRLTEELNKEAT 205
Query: 132 QHKHVEAELRSR-----LATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTL 186
+ ++ EL R +A L+ E Q Q ++D +T + EKL+++ KL+ SQ
Sbjct: 206 VIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQ--SQYA 263
Query: 187 EKEAKECRLRTE------ECQLQLKTLHEDLS--GRLEESLSIINEKVPFNDTKYS---- 234
EA +LR+E E + ++ L + S L + + E + + Y+
Sbjct: 264 SSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEE 323
Query: 235 QYNALNVPLHNRRHQLKMRDIAGQAL-AFVQDLVTALLNFHTYTEQRIQIFPVDSAIDTI 293
++N +V N + L +D+ Q L + + T+L H ++ + + +
Sbjct: 324 KHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGE--ATQKLKEEL 381
Query: 294 SPLNQKFSQYLHENASYVRPLEEGMLH---LFESITEDTVTVLETTVKLKTFSEHLTSYI 350
S + K+ E + EE H L I + +LET +L L
Sbjct: 382 SEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQ- 440
Query: 351 CFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPST 410
R++ +L E++ + L+ + L + +K+ +LQ +
Sbjct: 441 ---RQLSSEKLMDKEQQ------VADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQ 491
Query: 411 EPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCIL 470
E L S + A + V++ I + +E L + + +
Sbjct: 492 EQQAL----QQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKERE 547
Query: 471 SSVVALTNGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAAYMKS 530
+ G G+ A + L ++ L+ + Q + A ++
Sbjct: 548 DLYAKIQAGEGETA---------VLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQA-QEN 597
Query: 531 LRKPLLESVPYEEALANRRILLSSTESREGLAQQVQQSLEKISKLE---QEKEHWMLEAQ 587
L + E + A +R +LS S L Q+ +S EK+S+L+ + K +L A+
Sbjct: 598 LHDQVQEQKAHLRAAQDR--VLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAE 655
Query: 588 LAKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVP 647
AK + Q D +N L QE + T D+ TAK + + L
Sbjct: 656 AAKTAQRADLQNHLDTAQNA----LQDKQQELNKI--TTQLDQVTAKLQDKQEHCSQL-- 707
Query: 648 DVESREDLIKNHYMA---RIVELTSQLQLADSKSVHFYAECRALSKRLALAE-KSKEALT 703
ES K Y++ + EL Q++ ++ S+ A SK AL + + + L
Sbjct: 708 --ESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKA-----SKEQALQDLQQQRQLN 760
Query: 704 EEMKLASQNISR---LQDELTTTKRSYEDQLSMMSDHLCSMNETLSKQREEIDTLKMSSK 760
+++L + +S+ ++ E+ ++ R L S+ L S+ + L+KQ EE LK +
Sbjct: 761 TDLELRATELSKQLEMEKEIVSSTRL---DLQKKSEALESIKQKLTKQEEEKQILKQDFE 817
Query: 761 GNSKKNK 767
S++ K
Sbjct: 818 TLSQETK 824
Score = 43.1 bits (100), Expect = 0.001
Identities = 40/194 (20%), Positives = 85/194 (43%), Gaps = 7/194 (3%)
Query: 13 LAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKR 72
L S+ +NQ K ++D + LK QL+++ ++ K Q+E+ + + + +
Sbjct: 869 LKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQ 928
Query: 73 VELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEADEQ 132
++L + + + + K E Q Q + + ++K ++ E L + A Q
Sbjct: 929 LKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQ 988
Query: 133 HKHVEAELRSRLATLETEAAQHQAVVDGLTRKY---METIEKLQND----KAKLEVKSQT 185
+E +L+ +L E A + + L Y ET ++LQ+D +++L Q
Sbjct: 989 KTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQD 1048
Query: 186 LEKEAKECRLRTEE 199
L+ ++ L E+
Sbjct: 1049 LKSVEEKLSLAQED 1062
Score = 42.0 bits (97), Expect = 0.002
Identities = 47/200 (23%), Positives = 90/200 (45%), Gaps = 20/200 (10%)
Query: 6 LQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFR 65
L+ Q L Q+ +L+ + LK V E+ N LK+Q+K +++ L+K F
Sbjct: 1161 LKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKK--------EFI 1212
Query: 66 NLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQ 125
+ E+ + E+ + KK E+ ++L+ Q + +E+L +E + +
Sbjct: 1213 EKEAKLHSEIKEKEVGM--------KKHEENEAKLTM-QITALNENLGTVKKEWQSSQRR 1263
Query: 126 FFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQT 185
E ++Q + E+ AT++ + +A+++ + E IEKLQ +L+ K
Sbjct: 1264 VSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGE-IEKLQTKVLELQRKLDN 1322
Query: 186 LEKEAKECRLRTEECQLQLK 205
+E L E LQ+K
Sbjct: 1323 TTAAVQE--LGRENQSLQIK 1340
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 65.9 bits (159), Expect = 1e-10
Identities = 149/744 (20%), Positives = 283/744 (38%), Gaps = 119/744 (15%)
Query: 41 LKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQL 100
+KE L+ + ++L+++M SL L +V+ QD L +E E QL
Sbjct: 861 IKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAE----------ERCDQL 910
Query: 101 SQEQKSVFDEDLQKKIEE-NERLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVD 159
+ + L+ K++E NERL E + + AEL ++ LE E ++ + +D
Sbjct: 911 IKNK-----IQLEAKVKEMNERL--------EDEEEMNAELTAKKRKLEDECSELKKDID 957
Query: 160 GLTRKYMETIEKLQNDKAKLEVKSQTLEKE-----------AKECRLRTEECQLQLKTL- 207
L T+ K++ +K E K + L +E KE + E Q L L
Sbjct: 958 DLEL----TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQ 1013
Query: 208 -HEDLSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDL 266
ED L +S + ++V + Q + + L + +L+ L Q+
Sbjct: 1014 VEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLE------GDLKLTQES 1067
Query: 267 VTALLNFHTYTEQRIQ-----IFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHL 321
+ L N E++++ I +S I+ L + + L EN + + LEE +
Sbjct: 1068 IMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEEL--- 1124
Query: 322 FESITEDTVTVLETTVKLKTFSEHLTSYICFLRKILPYQLKSLEEECESSLCTSALRARN 381
E T + K LR L +L+ + E E + ++++
Sbjct: 1125 ----------EAERTARAKVEK---------LRSDLSRELEEISERLEEAGGATSVQ--- 1162
Query: 382 LELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDI 441
+E++ KK A F+K++ + L LR ++ + +G + V + +
Sbjct: 1163 IEMN---KKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKL 1219
Query: 442 SKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNNLDYFIASLSYG 501
K +K+ + EL T + ++ K++ + + + L
Sbjct: 1220 EK---EKSEFKLELDDVTSN--------MEQIIKAKANLEKVSRTLEDQANEYRVKLEEA 1268
Query: 502 PKAASGF------ISPLSAECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLSST 555
++ + F + + E Q ++K A + R L + E+ +R L
Sbjct: 1269 QRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDL---KRQLEEEG 1325
Query: 556 ESREGLAQQVQQSLEKISKL-EQEKEHWMLEAQLAKIKLEKENQRIADKLKNTGSAQLVG 614
+++ LA +Q + L EQ +E +A+L ++ L K N +A
Sbjct: 1326 KAKNALAHALQSARHDCDLLREQYEEETEAKAELQRV-LSKANSEVAQWRTK-------- 1376
Query: 615 LAQENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVE---SREDLIKNHYMARIVELTSQL 671
E A+ T +EA K + V V S + K+ I +L +
Sbjct: 1377 --YETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDV 1434
Query: 672 QLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQL 731
+ +++ + + R K LA ++ E E++ + + L EL K +YE+ L
Sbjct: 1435 ERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESL 1494
Query: 732 SMMSDHLCSMNETLSKQREEIDTL 755
+HL + +EEI L
Sbjct: 1495 ----EHLETFKRENKNLQEEISDL 1514
Score = 63.9 bits (154), Expect = 5e-10
Identities = 149/805 (18%), Positives = 307/805 (38%), Gaps = 141/805 (17%)
Query: 3 SAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSL 62
+AEL K +KL E S+L KK + D + A ++++ + ++ L +EM L
Sbjct: 935 NAELTAKKRKLEDECSEL-------KKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 987
Query: 63 TFRNLQLAKRVELLQD--ELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENE 120
+L K + LQ+ + AL + + +++K + S S++ EQ+ +DL+ +E+ +
Sbjct: 988 DEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQV---DDLEGSLEQEK 1044
Query: 121 RLHIQFFEADEQ--------------HKHVEAELRSRLATLETEAAQHQAVVDGLTRKYM 166
++ + A + ++ + +L +L E + Q + ++ +
Sbjct: 1045 KVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLAL 1104
Query: 167 ETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKV 226
+ +KL+ ++A++E + LE E + R + E+ + L E++S RLEE+ + ++
Sbjct: 1105 QLQKKLKENQARIEELEEELEAE-RTARAKVEKLRSDLSRELEEISERLEEAGGATSVQI 1163
Query: 227 PFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPV 286
N + +++ KMR +A + AL H + + +
Sbjct: 1164 EMNKKREAEFQ-------------KMRRDLEEATLQHEATAAALRKKHADS-----VAEL 1205
Query: 287 DSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHL 346
ID + + QK + E F+ +D + +E +K K E +
Sbjct: 1206 GEQIDNLQRVKQKLEKEKSE---------------FKLELDDVTSNMEQIIKAKANLEKV 1250
Query: 347 TSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLA 406
+ ++LE++ + R + E + + T KLQT LA
Sbjct: 1251 S--------------RTLEDQ------ANEYRVKLEEAQRSLNDFTTQRAKLQTENGELA 1290
Query: 407 LPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTN 466
E + L+ S LT + M+D+ + ++ ++ L A Q
Sbjct: 1291 RQLEEKEALI-----SQLTR---GKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDC 1342
Query: 467 DCILSSVVALTNGAGKIASFFSN-NLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAA 525
D + T ++ S N + Y A +Q ++
Sbjct: 1343 DLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA-------------IQRTEELE 1389
Query: 526 AYMKSLRKPLLESVPYEEALANRRILLSSTESR-----EGLAQQVQQSLEKISKLEQEKE 580
K L + L ++ EA+ + L T+ R E L V++S + L++++
Sbjct: 1390 EAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR 1449
Query: 581 H-------WMLEAQLAKIKLEKENQRIAD------KLKNTGSAQLVGLAQENAAVSNTAG 627
+ W + + ++ +LE + KLKN L L N
Sbjct: 1450 NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQE 1509
Query: 628 QDEATAKAVLEPIQSTSLVPDVESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRA 687
+ + + E ++ + V + ++ K + + E + L+ + K + E
Sbjct: 1510 EISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQ 1569
Query: 688 LSKRL--ALAEKSKEALTEEMKLASQNISRLQDELTTT--------------KRSYEDQL 731
+ + LAEK EEM+ A +N R+ D L T+ K+ E L
Sbjct: 1570 IKAEIERKLAEKD-----EEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDL 1624
Query: 732 SMMSDHLCSMNETLSKQREEIDTLK 756
+ M L N ++ ++++ +L+
Sbjct: 1625 NEMEIQLSHANRMAAEAQKQVKSLQ 1649
Score = 55.5 bits (132), Expect = 2e-07
Identities = 161/810 (19%), Positives = 322/810 (39%), Gaps = 100/810 (12%)
Query: 11 QKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLA 70
+K E+ K+R L++ + +A +AAL+ K S+ +L +++D+L +L
Sbjct: 1167 KKREAEFQKMRRD---LEEATLQHEATAAALR---KKHADSVAELGEQIDNLQRVKQKLE 1220
Query: 71 KR---VELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFF 127
K +L D++ + + K K + E S+ ++Q + + + K+EE +R F
Sbjct: 1221 KEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEY----RVKLEEAQRSLNDFT 1276
Query: 128 EADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLE 187
A+L++ L + + +A++ LTR + +++++ K +LE + +
Sbjct: 1277 TQ-------RAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKN 1329
Query: 188 KEAKECRLRTEECQLQLKTLHEDLSGR--LEESLSIINEKVPFNDTKYSQYNAL--NVPL 243
A + +C L + E+ + L+ LS N +V TKY + +A+ L
Sbjct: 1330 ALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY-ETDAIQRTEEL 1388
Query: 244 HNRRHQLKMR-DIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVD-----SAIDTISPLN 297
+ +L R A +A+ V ++L + I+ VD +A +
Sbjct: 1389 EEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQ 1448
Query: 298 QKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLK-TFSEHLTSYICFLRKI 356
+ F + L A + + EE L ES ++ ++ KLK + E L F R
Sbjct: 1449 RNFDKIL---AEWKQKYEESQSEL-ESSQKEARSLSTELFKLKNAYEESLEHLETFKR-- 1502
Query: 357 LPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLL 416
+ K+L+EE +N+ + ++K V EKL+ AL E + L
Sbjct: 1503 ---ENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEV-EKLELQSAL-----EEAEASL 1553
Query: 417 RTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVVAL 476
+L A F+ + +I + ++K + Q+++ + L +
Sbjct: 1554 EHEEGKIL----RAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRS 1609
Query: 477 TNGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAAYMKSLRKPLL 536
N ++ +L+ LS+ + ++AE Q K + +K + L
Sbjct: 1610 RNEVLRVKKKMEGDLNEMEIQLSHANR--------MAAEAQKQV-KSLQSLLKDTQIQLD 1660
Query: 537 ESVPYEEALANRRILLSSTESREGLAQ----QVQQSLEKISKLEQEKEHWMLEAQLAKIK 592
++V + L ++ E R L Q +++ +E+ + + E ++E
Sbjct: 1661 DAVRANDDLKEN---IAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQL 1717
Query: 593 LEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAV---------LEPIQST 643
L +N + ++ K S ++ AV +E KA+ L+ Q T
Sbjct: 1718 LHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDT 1777
Query: 644 S--LVPDVESREDLIKN--HYMARIVELT-----SQLQLADSKSVHFYAECRALSKR--- 691
S L ++ E IK+ H + ++ QLQ +++ E A KR
Sbjct: 1778 SAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAE 1837
Query: 692 ----LALAEKSKEALTEEMKLASQNISRLQ---DELTTTKRSYEDQLSMMSDHLCSMNET 744
+ +E+ + LT + + +N+ RLQ D+L ++Y+ Q + +
Sbjct: 1838 SVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSK 1897
Query: 745 LSKQREEIDTLK-----MSSKGNSKKNKSR 769
K + E+D + S+ N + KSR
Sbjct: 1898 FRKVQHELDEAEERADIAESQVNKLRAKSR 1927
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 65.5 bits (158), Expect = 2e-10
Identities = 168/824 (20%), Positives = 325/824 (39%), Gaps = 105/824 (12%)
Query: 11 QKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLA 70
++L E L +N++L+K + + LK+ + + L+QE L N +L
Sbjct: 628 EELENELHHLEKENELLQKKITN-----------LKITCEKIEALEQENSELERENRKLK 676
Query: 71 KRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQ--------KKIE-ENER 121
K ++ ++ E K+N + E + +L + +S+ ++ K++E E E+
Sbjct: 677 KTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQ 736
Query: 122 LHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEV 181
L K E L L+ E + Q ++ +K I++L+++ LE+
Sbjct: 737 LKKGLELLKASFKKTE-RLEVSYQGLDIENQRLQKTLENSNKK----IQQLESELQDLEM 791
Query: 182 KSQTLEKEAKECRL---RTEECQLQLKTLHEDLS------GRLEESLSIINEKVPFNDTK 232
++QTL+K +E ++ R E+ + + K+L ++ S +LE+ + ++ DT
Sbjct: 792 ENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTT 851
Query: 233 YSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAIDT 292
+ NV + N + K + + ++ L ++ ++ +D I T
Sbjct: 852 LEEN---NVKIGNLEKENK---TLSKEIGIYKESCVRLKELEKENKELVKRATID--IKT 903
Query: 293 ISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVL----ETTVKLKTFSEHLTS 348
+ L + + LE+ + H E I + +L T + K L S
Sbjct: 904 LVTLREDLVSEKLKTQQMNNDLEK-LTHELEKIGLNKERLLHDEQSTDDRYKLLESKLES 962
Query: 349 YICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKL-QTYIALLAL 407
+ +I ++ +LE E S N +L Q++K + +E L Q +
Sbjct: 963 TLKKSLEIKEEKIAALEARLEES------TNYNQQLRQELKTVKKNYEALKQRQDEERMV 1016
Query: 408 PSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTND 467
S+ P + L D + ++ ++ + A + L T ++L T N+
Sbjct: 1017 QSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNN 1076
Query: 468 CILSSVVAL-----------TNGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAEC 516
+ + ++AL T + A N S S + A I S E
Sbjct: 1077 NLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLEN 1136
Query: 517 MLQYKKKAAAYMKSLRKPLLESVPYEEALANRRIL-LSSTESREGLAQQVQQSLE-KISK 574
+ K +KSL L++ E L R+ S S+ G + ++LE +
Sbjct: 1137 ENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRD 1196
Query: 575 LEQE-----KEHWMLEAQLAKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQD 629
LE K+ LE +K+E+E + +K T +A+ L EN +++T Q
Sbjct: 1197 LEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQ- 1255
Query: 630 EATAKAVLEPIQSTSLVPDVESREDLIKNHYM------ARIVELTSQLQLADSKSVHFYA 683
+L+ ++ L D ++ + L+ N + A +L Q Q D S
Sbjct: 1256 ------LLK--ETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNN 1307
Query: 684 ECRALSK-RLALAEKSKEALTEEMKLASQNISRLQDELTT------TKRSYEDQLSMMSD 736
+C LS+ + L E+++ L + L QN + L+ + + +R Y D+L+ +
Sbjct: 1308 QCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRR 1367
Query: 737 HLCSMNETLSKQREEID-----------TLKMSSKGNSKKNKSR 769
+ E + Q + D TLKM SKK+ +R
Sbjct: 1368 QKEKLEEKIMDQYKFYDPSPPRRRGNWITLKMRKLIKSKKDINR 1411
Score = 49.7 bits (117), Expect = 1e-05
Identities = 145/750 (19%), Positives = 292/750 (38%), Gaps = 88/750 (11%)
Query: 41 LKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQL 100
L +L +R+L+QE++ T + L + +E ++ EL + S+
Sbjct: 249 LSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMY 308
Query: 101 SQE-----QKSVFDEDLQKKIEE-NERLH-IQFFEADEQHKHVEAELRSRLATLETEAAQ 153
E +K+V + L+ ++ ERLH I+F++A VE LET+
Sbjct: 309 RDELDALREKAVRVDKLESEVSRYKERLHDIEFYKA-----RVEELKEDNQVLLETKTML 363
Query: 154 HQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSG 213
+ TR + + +L+ + +L+ K +E E R + EE + TL
Sbjct: 364 EDQLEG--TRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQ 421
Query: 214 RLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNF 273
++ESL + E + T P + H+ + ++ L ++ +L
Sbjct: 422 SMDESLHLGWELEQISRTS----ELSEAPQKSLGHE--VNELTSSRLLKLEMENQSLTK- 474
Query: 274 HTYTEQRIQIFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVL 333
T E R + V+ I + +K +Q L + V LE ++ +S+ ++ +
Sbjct: 475 -TVEELRTTVDSVEGNASKILKM-EKENQRLSKK---VEILENEIVQEKQSL-QNCQNLS 528
Query: 334 ETTVKLKTFSEHLTSYICFLRKILPYQLKSLEEECES-SLCTSALRARNLELSQDMKKMT 392
+ +K K L I LR+ Q+K LE+E E + S+LR R+ ++S + +
Sbjct: 529 KDLMKEKA---QLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRS-QISAEARVKD 584
Query: 393 AVFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIE 452
E + +L + + + + K++ +HY +K
Sbjct: 585 IEKE----------------NKILHESIKETSSKLSKIEFEKRQIKKEL-EHYKEKGERA 627
Query: 453 HELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNN-------------LDYFIASLS 499
EL L N+ + + L KI + N LD F +L+
Sbjct: 628 EELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSF-KNLT 686
Query: 500 YGPKAASGFISPLSAECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLSSTESRE 559
+ ++ S L E + + + S++ L+ L N+ + + ++
Sbjct: 687 FQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQ-------LENKELESEKEQLKK 739
Query: 560 GLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRIADKLKNTGSAQLVGLAQEN 619
GL + ++ S +K +LE + +E Q + LE N++I ++L L EN
Sbjct: 740 GL-ELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQL-----ESELQDLEMEN 793
Query: 620 AAVSNTAGQDEATAKAVLEPIQSTSLVPDVESREDLIKNHYMARIVELTSQLQLADS--- 676
+ + + ++K + + + + S+ + K L Q ++ D+
Sbjct: 794 QTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLE 853
Query: 677 ----KSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLS 732
K + E + LSK + + ++S L E K + + R ++ T ED
Sbjct: 854 ENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLRED--- 910
Query: 733 MMSDHLCS--MNETLSKQREEIDTLKMSSK 760
++S+ L + MN L K E++ + ++ +
Sbjct: 911 LVSEKLKTQQMNNDLEKLTHELEKIGLNKE 940
Score = 49.7 bits (117), Expect = 1e-05
Identities = 134/728 (18%), Positives = 293/728 (40%), Gaps = 118/728 (16%)
Query: 1 MASAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQA---NSAALKEQLKMKDQSLRKLQQ 57
+ + EL+ + ++L + L+A + ++ V Q + L++ L+ ++ +++L+
Sbjct: 725 LENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLES 784
Query: 58 EMDSLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDED----LQ 113
E+ L N L K +E L+ E K+NK + +SQL +++K + E+ Q
Sbjct: 785 ELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Query: 114 KKIEEN--ERLHIQFFEADEQHKHVEAELR------SRLATLETEAAQ--HQAVVDGLTR 163
+I++ E +++ ++++K + E+ RL LE E + +A +D
Sbjct: 845 AEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATID---- 900
Query: 164 KYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQL--------------QLKTLHE 209
++T+ L+ D ++K+Q + + ++ E+ L + K L
Sbjct: 901 --IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLES 958
Query: 210 DLSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTA 269
L L++SL I EK+ + + + N L Q+L T
Sbjct: 959 KLESTLKKSLEIKEEKIAALEARLEESTNYNQQLR-------------------QELKTV 999
Query: 270 LLNFHTYTEQRIQIFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDT 329
N+ +++ + + + + P++ + +++ E+ R L + L E + +
Sbjct: 1000 KKNYEALKQRQDE----ERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIE-VERNN 1054
Query: 330 VTV------LETTVK-LKTFSEHLTSYICFLRKILPYQLKSLEEECESSLCTSALRARNL 382
T+ L+T +K L+T + +L + I L++ Q SL+E+ + L+ +N
Sbjct: 1055 ATLQAEKQALKTQLKQLETQNNNLQAQILALQR----QTVSLQEQ------NTTLQTQNA 1104
Query: 383 ELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDIS 442
+L + + + L A L + + L SV+ + ++KD
Sbjct: 1105 KLQVENSTLNSQSTSLMNQNAQLLIQQSS----LENENESVIKEREDLKSLYDSLIKD-- 1158
Query: 443 KHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNNLDYFIASLSYGP 502
+K + HE + + + + L S A K +L+ L
Sbjct: 1159 ---HEKLELLHERQASEYESLISKHGTLKS-------AHKNLEVEHRDLEDRYNQL---- 1204
Query: 503 KAASGFISPLSAECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLSSTESREGLA 562
G + L E ML+ +++ K LLE+ +E A + L +
Sbjct: 1205 LKQKGQLEDL--EKMLKVEQE---------KMLLENKNHETVAAEYKKLCGENDRLNHTY 1253
Query: 563 QQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRIADKLKNTGSAQLVGLAQENAAV 622
Q+ + E + + + + ++L + +LE E ++ ++ + L + +
Sbjct: 1254 SQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITS-TKLNNQCELL 1312
Query: 623 SNTAGQDEATAKAVLEPIQS------TSLVPDVESRE--DLIKNHYMARIVELTSQLQLA 674
S G E + +L+ IQ+ T L ++ES++ + + Y+ ++ EL Q +
Sbjct: 1313 SQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKL 1372
Query: 675 DSKSVHFY 682
+ K + Y
Sbjct: 1373 EEKIMDQY 1380
Score = 44.3 bits (103), Expect = 4e-04
Identities = 50/228 (21%), Positives = 112/228 (49%), Gaps = 28/228 (12%)
Query: 32 VDEQANSAALKEQLKMKDQSLRKLQQEMDS--------------LTFRNLQLAKRVELLQ 77
V+E +S LK L+M++QSL K +E+ + + N +L+K+VE+L+
Sbjct: 454 VNELTSSRLLK--LEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILE 511
Query: 78 DELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEADEQHKHVE 137
+E+ + K++ ++ ++ S+ ++K+ ++ ++ E +ER I+ E + +H +
Sbjct: 512 NEIV----QEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSER-QIKILEQENEHLNQT 566
Query: 138 AELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEA---KECR 194
+ + + EA ++ + E+I++ + +K+E + + ++KE KE
Sbjct: 567 VSSLRQRSQISAEARVKD--IEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKG 624
Query: 195 LRTEECQLQLKTLHE--DLSGRLEESLSIINEKVPFNDTKYSQYNALN 240
R EE + +L L + +L + +L I EK+ + + S+ N
Sbjct: 625 ERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELEREN 672
Score = 34.3 bits (77), Expect = 0.45
Identities = 52/231 (22%), Positives = 94/231 (40%), Gaps = 33/231 (14%)
Query: 555 TESREGLAQQVQQSLEK-ISKLEQEKEHWMLEAQLAKI-KLEKENQRIADKLKNTGSAQL 612
T SR + QSL K + +L + +E +KI K+EKENQR++ K++ +
Sbjct: 458 TSSRLLKLEMENQSLTKTVEELRTTVDS--VEGNASKILKMEKENQRLSKKVEILENE-- 513
Query: 613 VGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVESREDLIKNHYMARIVELTSQLQ 672
+ QE ++ N + K + ++ + + R+ I + + S L+
Sbjct: 514 --IVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLR 571
Query: 673 LADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYE---- 728
S AE R EK + L E +K S +S+++ E K+ E
Sbjct: 572 QRSQIS----AEARVKD-----IEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKE 622
Query: 729 -----DQLSMMSDHLCSMNETLSKQ-------REEIDTLKMSSKGNSKKNK 767
++L HL NE L K+ E+I+ L+ + ++N+
Sbjct: 623 KGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENR 673
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 65.5 bits (158), Expect = 2e-10
Identities = 146/749 (19%), Positives = 286/749 (38%), Gaps = 87/749 (11%)
Query: 3 SAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSL 62
+A+L G+ + L Q ++ + + L+ V + Q+ + + + + KLQ E++S+
Sbjct: 1233 NADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV 1292
Query: 63 TF-------RNLQLAKRV----ELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDE- 110
T + ++LAK V LQD L + ++ QL +E+ S+ D+
Sbjct: 1293 TGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQL 1352
Query: 111 DLQKKIEENERLHIQFFEAD-EQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYME-- 167
D + + ++N HI K + S + LE + Q ++ LT++Y E
Sbjct: 1353 DEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKA 1412
Query: 168 -TIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKV 226
+KL+ K +L Q +L L DL + + ++ ++
Sbjct: 1413 AAYDKLEKTKNRL---------------------QQELDDLVVDLDNQRQLVSNLEKKQR 1451
Query: 227 PFNDTKYSQYNALNVPLHNR-RHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFP 285
F+ + N + R R + + R+ +AL+ + L AL E
Sbjct: 1452 KFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEAL---EAKEELERTNKM 1508
Query: 286 VDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEH 345
+ + ++ + + +HE R LE M + + E+ L+ T K
Sbjct: 1509 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQL-EELEDELQATEDAKL---R 1564
Query: 346 LTSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALL 405
L + L+ L++ +E+ E + +L + + + E + AL
Sbjct: 1565 LEVNMQALKGQFERDLQARDEQNEE---------KRRQLQRQLHEYETELEDERKQRALA 1615
Query: 406 ALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITT 465
A + +G L+ + +A+ G + +K + K +Q + EL A
Sbjct: 1616 AAAKKKLEGDLK----DLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR--- 1668
Query: 466 NDCILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKA-----------ASGFISPLSA 514
+ A K A +L L+ +A A S LS
Sbjct: 1669 -----DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSG 1723
Query: 515 ECMLQ-YKKKAAAYMKSLRKPLLESVPYEEALANRRILLSSTESREGLAQQVQQSLEKIS 573
LQ K++ A + L + L E EA+++R + +T+ E L+ ++
Sbjct: 1724 RNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR--VRKATQQAEQLSNELATERSTAQ 1781
Query: 574 KLEQEKEHWMLEAQLAKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATA 633
K E ++ + + + KL + + K K+T +A +AQ V A + +A
Sbjct: 1782 KNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAAT 1841
Query: 634 KAVLEPIQSTS-LVPDVESREDLIKNHYM------ARIVELTSQLQLADSKSVHFYAECR 686
K++ + + ++ VE + + + AR+ +L QL+ A+ +S A R
Sbjct: 1842 KSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRR 1901
Query: 687 ALSKRLALAEKSKEALTEEMKLASQNISR 715
L + L A +S EA+ E+ + R
Sbjct: 1902 KLQRELDEATESNEAMGREVNALKSKLRR 1930
Score = 64.3 bits (155), Expect = 4e-10
Identities = 175/869 (20%), Positives = 343/869 (39%), Gaps = 121/869 (13%)
Query: 5 ELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTF 64
E + + Q+L E K+ Q L++ + +E+A L+ + + ++KL+ E+ +
Sbjct: 933 EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDD 992
Query: 65 RNLQLAKRVELLQDELA---------------LSEPRGKKNKKSGESSSQLSQEQKSVFD 109
+N +L+K +LL++ ++ L++ + K E +L +E+KS +
Sbjct: 993 QNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQE 1052
Query: 110 -EDLQKKIEENER--------LHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDG 160
E L++K+E + L Q E Q E EL++ LA L+ E AQ +
Sbjct: 1053 LEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKK 1112
Query: 161 LTRKYMETIEKLQNDKAKLEVKSQTLEKEAKEC-----RLRTE-ECQLQLKTLHEDLSGR 214
+ R+ I LQ D EK+ ++ L+TE E L ++L +
Sbjct: 1113 I-RELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAK 1171
Query: 215 LEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFH 274
E+ ++++ + + D + + A V ++H + ++ Q F + N
Sbjct: 1172 REQEVTVLKKAL---DEETRSHEA-QVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1227
Query: 275 TYTEQRI----QIFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITE--- 327
T ++ ++ + A + +K + E S E L + + +
Sbjct: 1228 TLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1287
Query: 328 --DTVTVLETTVKLKTFSEHLTSYICFLRKILPYQLKSLEEECESSLCTSALRARNLE-- 383
++VT + + K L + L L + L+EE L S + R LE
Sbjct: 1288 EVESVTGMLNEAEGKAIK--LAKDVASLSSQLQDTQELLQEETRQKLNVST-KLRQLEEE 1344
Query: 384 ---LSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKD 440
L + + + L+ +I+ L + ++ L+ +++S + + F +++
Sbjct: 1345 RNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEIEN 1403
Query: 441 ISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNNLDYFIASLSY 500
+++ Y +KAA +L +L D + VV L N ++ S F L+
Sbjct: 1404 LTQQYEEKAAAYDKLEKTKNRLQQELDDL---VVDLDN-QRQLVSNLEKKQRKFDQLLAE 1459
Query: 501 GPKAASGFISPLS-AECMLQYKKKAAAYMKSLRKPLLESVPYEEAL-ANRRILLSSTESR 558
+S + AE + K+ A SL + L E++ +E L ++L + E
Sbjct: 1460 EKNISSKYADERDRAEAEAREKETKAL---SLARALEEALEAKEELERTNKMLKAEMEDL 1516
Query: 559 EGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRIAD----------KLKNTG 608
V +++ ++ K ++ E M E + +LE E Q D LK
Sbjct: 1517 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1576
Query: 609 SAQLVGLAQENAAVS----------NTAGQDE-------ATAKAVLE-PIQSTSLVPD-- 648
L ++N T +DE A AK LE ++ L D
Sbjct: 1577 ERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSA 1636
Query: 649 VESREDLIK--NHYMARIVELTSQLQLA--------------DSKSVHFYAECRALSKRL 692
++ RE+ IK A++ + +L+ A + K+ A+ L + L
Sbjct: 1637 IKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1696
Query: 693 ALAEKS-------KEALTEEMKLASQNISRLQDE---LTTTKRSYEDQLSMMSDHLCSMN 742
A AE++ KE L EE+ + + LQDE L E++L ++ +M+
Sbjct: 1697 AAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMS 1756
Query: 743 ETLSK---QREEIDTLKMSSKGNSKKNKS 768
+ + K Q E++ + + ++KN+S
Sbjct: 1757 DRVRKATQQAEQLSNELATERSTAQKNES 1785
Score = 40.8 bits (94), Expect = 0.005
Identities = 54/243 (22%), Positives = 100/243 (41%), Gaps = 27/243 (11%)
Query: 512 LSAECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLSSTESREGLAQQVQQSLEK 571
L AE L + + + +K LE + +E + + E E QQ+Q +K
Sbjct: 896 LQAETELYAEAEEMRVRLAAKKQELEEILHE--------MEARLEEEEDRGQQLQAERKK 947
Query: 572 ISKLEQEKEHWMLEAQLAKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEA 631
+++ + E + E + A+ KL+ E K T A++ L E + + +
Sbjct: 948 MAQQMLDLEEQLEEEEAARQKLQLE--------KVTAEAKIKKLEDEILVMDDQNNKLSK 999
Query: 632 TAKAVLEPIQ--STSLVPDVESREDL--IKNHYMARIVELTSQLQLADSKSVHFYAECRA 687
K + E I +T+L + E ++L +KN + + I EL +L+ K E
Sbjct: 1000 ERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK----KEEKSRQELEK 1055
Query: 688 LSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSK 747
L ++L E E++ I+ L+ +L + + L+ + D + N L K
Sbjct: 1056 LKRKL---EGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKK 1112
Query: 748 QRE 750
RE
Sbjct: 1113 IRE 1115
Score = 39.3 bits (90), Expect = 0.014
Identities = 163/806 (20%), Positives = 312/806 (38%), Gaps = 123/806 (15%)
Query: 21 RAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQ--- 77
+ Q Q+ V+ Q N AA LK+++ +L ++ L LQ+ ++ E +Q
Sbjct: 808 KRQQQLTAMKVI--QRNCAAY---LKLRNWQWWRLFTKVKPL----LQVTRQEEEMQAKE 858
Query: 78 DELALSEPRGKKN----KKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEADEQH 133
DEL ++ R +K K+ + SQL++E K++ E LQ + E + EA+E
Sbjct: 859 DELQKTKERQQKAENELKELEQKHSQLTEE-KNLLQEQLQAETE-------LYAEAEE-- 908
Query: 134 KHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEAKEC 193
+R RLA + E + ++ + + ++LQ ++ K+ + LE++ +E
Sbjct: 909 ------MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE 962
Query: 194 RLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMR 253
++ QL+ T + +LE+ + +++++ N L R L+ R
Sbjct: 963 EAARQKLQLEKVTAEAKIK-KLEDEILVMDDQ--------------NNKLSKERKLLEER 1007
Query: 254 DIAGQALAFVQDLVTALLNFHTYTEQRIQI-FPVDSAIDTISPLNQKFSQYLHENASYVR 312
+ DL T L + ++ +S I + +K + E R
Sbjct: 1008 ---------ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR 1058
Query: 313 PLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSYIC-----------FLRKI--LPY 359
LE E I + + E ++L E L + + L+KI L
Sbjct: 1059 KLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEG 1118
Query: 360 QLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTN 419
+ L+E+ +S RA + + + + E L+T + L ST LR
Sbjct: 1119 HISDLQEDLDSE------RAARNKAEKQKRDLGEELEALKTELE-DTLDSTATQQELRAK 1171
Query: 420 YSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNG 479
+T + AL ++ H +Q + + A ++L + + L
Sbjct: 1172 REQEVTVLKKALD------EETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKN 1225
Query: 480 AGKIASFFSN------NLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAA------- 526
+ ++ L + + K + L ++C + +A
Sbjct: 1226 KQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKL 1285
Query: 527 --YMKSLRKPLLESVPYEEALANRRILLSS--TESREGLAQQVQQSLEKISKLEQ-EKEH 581
++S+ L E+ LA LSS +++E L ++ +Q L +KL Q E+E
Sbjct: 1286 QNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1345
Query: 582 WMLEAQL-----AKIKLEKE----NQRIADKLK------NTGSAQLVGLAQENAAVSNTA 626
L+ QL AK LE+ N +++D K +T A G + + N
Sbjct: 1346 NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLT 1405
Query: 627 GQDEATAKAVLEPIQSTSLVPDVESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECR 686
Q E A A + ++ T E +DL+ + R +L S L+ K AE +
Sbjct: 1406 QQYEEKA-AAYDKLEKTKNRLQQE-LDDLVVDLDNQR--QLVSNLEKKQRKFDQLLAEEK 1461
Query: 687 ALSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMS---DHLCSMNE 743
+S + A EA E + + +++R +E K E M+ + L S +
Sbjct: 1462 NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD 1521
Query: 744 TLSKQREEIDTLKMSSKGNSKKNKSR 769
+ K E++ K + + ++ K++
Sbjct: 1522 DVGKNVHELEKSKRALETQMEEMKTQ 1547
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 65.5 bits (158), Expect = 2e-10
Identities = 146/749 (19%), Positives = 286/749 (38%), Gaps = 87/749 (11%)
Query: 3 SAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSL 62
+A+L G+ + L Q ++ + + L+ V + Q+ + + + + KLQ E++S+
Sbjct: 1240 NADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV 1299
Query: 63 TF-------RNLQLAKRV----ELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDE- 110
T + ++LAK V LQD L + ++ QL +E+ S+ D+
Sbjct: 1300 TGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQL 1359
Query: 111 DLQKKIEENERLHIQFFEAD-EQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYME-- 167
D + + ++N HI K + S + LE + Q ++ LT++Y E
Sbjct: 1360 DEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKA 1419
Query: 168 -TIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKV 226
+KL+ K +L Q +L L DL + + ++ ++
Sbjct: 1420 AAYDKLEKTKNRL---------------------QQELDDLVVDLDNQRQLVSNLEKKQR 1458
Query: 227 PFNDTKYSQYNALNVPLHNR-RHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFP 285
F+ + N + R R + + R+ +AL+ + L AL E
Sbjct: 1459 KFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEAL---EAKEELERTNKM 1515
Query: 286 VDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEH 345
+ + ++ + + +HE R LE M + + E+ L+ T K
Sbjct: 1516 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQL-EELEDELQATEDAKL---R 1571
Query: 346 LTSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALL 405
L + L+ L++ +E+ E + +L + + + E + AL
Sbjct: 1572 LEVNMQALKGQFERDLQARDEQNEE---------KRRQLQRQLHEYETELEDERKQRALA 1622
Query: 406 ALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITT 465
A + +G L+ + +A+ G + +K + K +Q + EL A
Sbjct: 1623 AAAKKKLEGDLK----DLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR--- 1675
Query: 466 NDCILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKA-----------ASGFISPLSA 514
+ A K A +L L+ +A A S LS
Sbjct: 1676 -----DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSG 1730
Query: 515 ECMLQ-YKKKAAAYMKSLRKPLLESVPYEEALANRRILLSSTESREGLAQQVQQSLEKIS 573
LQ K++ A + L + L E EA+++R + +T+ E L+ ++
Sbjct: 1731 RNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR--VRKATQQAEQLSNELATERSTAQ 1788
Query: 574 KLEQEKEHWMLEAQLAKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATA 633
K E ++ + + + KL + + K K+T +A +AQ V A + +A
Sbjct: 1789 KNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAAT 1848
Query: 634 KAVLEPIQSTS-LVPDVESREDLIKNHYM------ARIVELTSQLQLADSKSVHFYAECR 686
K++ + + ++ VE + + + AR+ +L QL+ A+ +S A R
Sbjct: 1849 KSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRR 1908
Query: 687 ALSKRLALAEKSKEALTEEMKLASQNISR 715
L + L A +S EA+ E+ + R
Sbjct: 1909 KLQRELDEATESNEAMGREVNALKSKLRR 1937
Score = 64.3 bits (155), Expect = 4e-10
Identities = 175/869 (20%), Positives = 343/869 (39%), Gaps = 121/869 (13%)
Query: 5 ELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTF 64
E + + Q+L E K+ Q L++ + +E+A L+ + + ++KL+ E+ +
Sbjct: 940 EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDD 999
Query: 65 RNLQLAKRVELLQDELA---------------LSEPRGKKNKKSGESSSQLSQEQKSVFD 109
+N +L+K +LL++ ++ L++ + K E +L +E+KS +
Sbjct: 1000 QNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQE 1059
Query: 110 -EDLQKKIEENER--------LHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDG 160
E L++K+E + L Q E Q E EL++ LA L+ E AQ +
Sbjct: 1060 LEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKK 1119
Query: 161 LTRKYMETIEKLQNDKAKLEVKSQTLEKEAKEC-----RLRTE-ECQLQLKTLHEDLSGR 214
+ R+ I LQ D EK+ ++ L+TE E L ++L +
Sbjct: 1120 I-RELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAK 1178
Query: 215 LEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFH 274
E+ ++++ + + D + + A V ++H + ++ Q F + N
Sbjct: 1179 REQEVTVLKKAL---DEETRSHEA-QVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1234
Query: 275 TYTEQRI----QIFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITE--- 327
T ++ ++ + A + +K + E S E L + + +
Sbjct: 1235 TLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1294
Query: 328 --DTVTVLETTVKLKTFSEHLTSYICFLRKILPYQLKSLEEECESSLCTSALRARNLE-- 383
++VT + + K L + L L + L+EE L S + R LE
Sbjct: 1295 EVESVTGMLNEAEGKAIK--LAKDVASLSSQLQDTQELLQEETRQKLNVST-KLRQLEEE 1351
Query: 384 ---LSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKD 440
L + + + L+ +I+ L + ++ L+ +++S + + F +++
Sbjct: 1352 RNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEIEN 1410
Query: 441 ISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNNLDYFIASLSY 500
+++ Y +KAA +L +L D + VV L N ++ S F L+
Sbjct: 1411 LTQQYEEKAAAYDKLEKTKNRLQQELDDL---VVDLDN-QRQLVSNLEKKQRKFDQLLAE 1466
Query: 501 GPKAASGFISPLS-AECMLQYKKKAAAYMKSLRKPLLESVPYEEAL-ANRRILLSSTESR 558
+S + AE + K+ A SL + L E++ +E L ++L + E
Sbjct: 1467 EKNISSKYADERDRAEAEAREKETKAL---SLARALEEALEAKEELERTNKMLKAEMEDL 1523
Query: 559 EGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRIAD----------KLKNTG 608
V +++ ++ K ++ E M E + +LE E Q D LK
Sbjct: 1524 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1583
Query: 609 SAQLVGLAQENAAVS----------NTAGQDE-------ATAKAVLE-PIQSTSLVPD-- 648
L ++N T +DE A AK LE ++ L D
Sbjct: 1584 ERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSA 1643
Query: 649 VESREDLIK--NHYMARIVELTSQLQLA--------------DSKSVHFYAECRALSKRL 692
++ RE+ IK A++ + +L+ A + K+ A+ L + L
Sbjct: 1644 IKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1703
Query: 693 ALAEKS-------KEALTEEMKLASQNISRLQDE---LTTTKRSYEDQLSMMSDHLCSMN 742
A AE++ KE L EE+ + + LQDE L E++L ++ +M+
Sbjct: 1704 AAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMS 1763
Query: 743 ETLSK---QREEIDTLKMSSKGNSKKNKS 768
+ + K Q E++ + + ++KN+S
Sbjct: 1764 DRVRKATQQAEQLSNELATERSTAQKNES 1792
Score = 40.8 bits (94), Expect = 0.005
Identities = 54/243 (22%), Positives = 100/243 (41%), Gaps = 27/243 (11%)
Query: 512 LSAECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLSSTESREGLAQQVQQSLEK 571
L AE L + + + +K LE + +E + + E E QQ+Q +K
Sbjct: 903 LQAETELYAEAEEMRVRLAAKKQELEEILHE--------MEARLEEEEDRGQQLQAERKK 954
Query: 572 ISKLEQEKEHWMLEAQLAKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEA 631
+++ + E + E + A+ KL+ E K T A++ L E + + +
Sbjct: 955 MAQQMLDLEEQLEEEEAARQKLQLE--------KVTAEAKIKKLEDEILVMDDQNNKLSK 1006
Query: 632 TAKAVLEPIQ--STSLVPDVESREDL--IKNHYMARIVELTSQLQLADSKSVHFYAECRA 687
K + E I +T+L + E ++L +KN + + I EL +L+ K E
Sbjct: 1007 ERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK----KEEKSRQELEK 1062
Query: 688 LSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSK 747
L ++L E E++ I+ L+ +L + + L+ + D + N L K
Sbjct: 1063 LKRKL---EGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKK 1119
Query: 748 QRE 750
RE
Sbjct: 1120 IRE 1122
Score = 39.3 bits (90), Expect = 0.014
Identities = 163/806 (20%), Positives = 312/806 (38%), Gaps = 123/806 (15%)
Query: 21 RAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQ--- 77
+ Q Q+ V+ Q N AA LK+++ +L ++ L LQ+ ++ E +Q
Sbjct: 815 KRQQQLTAMKVI--QRNCAAY---LKLRNWQWWRLFTKVKPL----LQVTRQEEEMQAKE 865
Query: 78 DELALSEPRGKKN----KKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEADEQH 133
DEL ++ R +K K+ + SQL++E K++ E LQ + E + EA+E
Sbjct: 866 DELQKTKERQQKAENELKELEQKHSQLTEE-KNLLQEQLQAETE-------LYAEAEE-- 915
Query: 134 KHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEAKEC 193
+R RLA + E + ++ + + ++LQ ++ K+ + LE++ +E
Sbjct: 916 ------MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE 969
Query: 194 RLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMR 253
++ QL+ T + +LE+ + +++++ N L R L+ R
Sbjct: 970 EAARQKLQLEKVTAEAKIK-KLEDEILVMDDQ--------------NNKLSKERKLLEER 1014
Query: 254 DIAGQALAFVQDLVTALLNFHTYTEQRIQI-FPVDSAIDTISPLNQKFSQYLHENASYVR 312
+ DL T L + ++ +S I + +K + E R
Sbjct: 1015 ---------ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR 1065
Query: 313 PLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSYIC-----------FLRKI--LPY 359
LE E I + + E ++L E L + + L+KI L
Sbjct: 1066 KLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEG 1125
Query: 360 QLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTN 419
+ L+E+ +S RA + + + + E L+T + L ST LR
Sbjct: 1126 HISDLQEDLDSE------RAARNKAEKQKRDLGEELEALKTELE-DTLDSTATQQELRAK 1178
Query: 420 YSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNG 479
+T + AL ++ H +Q + + A ++L + + L
Sbjct: 1179 REQEVTVLKKALD------EETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKN 1232
Query: 480 AGKIASFFSN------NLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAA------- 526
+ ++ L + + K + L ++C + +A
Sbjct: 1233 KQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKL 1292
Query: 527 --YMKSLRKPLLESVPYEEALANRRILLSS--TESREGLAQQVQQSLEKISKLEQ-EKEH 581
++S+ L E+ LA LSS +++E L ++ +Q L +KL Q E+E
Sbjct: 1293 QNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1352
Query: 582 WMLEAQL-----AKIKLEKE----NQRIADKLK------NTGSAQLVGLAQENAAVSNTA 626
L+ QL AK LE+ N +++D K +T A G + + N
Sbjct: 1353 NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLT 1412
Query: 627 GQDEATAKAVLEPIQSTSLVPDVESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECR 686
Q E A A + ++ T E +DL+ + R +L S L+ K AE +
Sbjct: 1413 QQYEEKA-AAYDKLEKTKNRLQQE-LDDLVVDLDNQR--QLVSNLEKKQRKFDQLLAEEK 1468
Query: 687 ALSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMS---DHLCSMNE 743
+S + A EA E + + +++R +E K E M+ + L S +
Sbjct: 1469 NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD 1528
Query: 744 TLSKQREEIDTLKMSSKGNSKKNKSR 769
+ K E++ K + + ++ K++
Sbjct: 1529 DVGKNVHELEKSKRALETQMEEMKTQ 1554
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 65.1 bits (157), Expect = 2e-10
Identities = 161/787 (20%), Positives = 293/787 (37%), Gaps = 96/787 (12%)
Query: 2 ASAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDS 61
+SA + + + L ++ +KLR QN L V + + E + + R ++S
Sbjct: 223 SSAPVDQEIKSLREKLNKLRQQNACL----VTQNHSLMTKFESIHFELTQSRAKVSMLES 278
Query: 62 LTFRNLQLAKRVELLQDELALSEPR-GKKNKKSGESSSQLSQEQKSVFDED--LQKKIEE 118
Q A V +L++++ E ++K E+ ++L Q QK V +++ LQ+ EE
Sbjct: 279 AQ----QQAASVPILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEE 334
Query: 119 NERLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAK 178
+L + E +Q K E + L E + Q +K E +EK+Q ++
Sbjct: 335 CIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKAFQQY----KKKVAEKLEKVQAEEEI 390
Query: 179 LEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNA 238
LE EKE K + E C G + L I+ EK+
Sbjct: 391 LERNLTNCEKENKRLQ---ERC------------GLYKSELEILKEKL----------RQ 425
Query: 239 LNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAIDTISP-LN 297
L +N + +L++ +A V A L TE R I ++S ++ L
Sbjct: 426 LKEENNNGKEKLRI-------MAVKNSEVMAQL-----TESRQSILKLESELENKDEILR 473
Query: 298 QKFSQYLHENASYVR-PLEEGMLHLFESITEDT---VTVLETTVKLKTFSEHLTSYICFL 353
KFS VR + L L + E + + LE + L + +L
Sbjct: 474 DKFSLMNENRELKVRVAAQNERLDLCQQEIESSRVELRSLEKIISQLPLKRELFGFKSYL 533
Query: 354 RKILPYQLKSLEEEC-----ESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALP 408
K + E+ C + L S LR + +++K+ A Q +L+
Sbjct: 534 SKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCN 593
Query: 409 STEPDGLLRTNYSSVLTN-VGAALHGFHDVMKDISKHYSQK--AAIEHELPTATQKLITT 465
++ L SS+ T V H + +KD ++H K L T ++L T
Sbjct: 594 DSQESSKL----SSLETEPVKLGGHQVAESVKDQNQHTMNKQYEKERQRLVTGIEELRTK 649
Query: 466 NDCILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECML--QYKKK 523
I + L S F + + S K S S L Q ++K
Sbjct: 650 LIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEK 709
Query: 524 AAAYMKSLRKPLLESVPYEEALANRRILLSSTESREGLA-QQVQQSLEKISKLEQEKEHW 582
AY K + E+ L + + S E+ +++ + EK K+ E +H
Sbjct: 710 IVAYSSIAAK----NAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLE-QHK 764
Query: 583 MLEAQLAKI--KLEKENQRIADKLKNTGSAQLVGLAQENAAVS--------------NTA 626
+E Q+ ++ +LEK++Q+ ++ K Q + +++ S
Sbjct: 765 EMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENM 824
Query: 627 GQDEATAKAVLEPIQSTSLVPDVESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECR 686
+DEA + + T V ++S ++ K + + +L + + + E
Sbjct: 825 KKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVY 884
Query: 687 ALSKRLALAEKSKEALTEEMKLASQNISRLQDEL---TTTKRSYEDQLSMMSDHLCSMNE 743
L K L + S + +E+ + + + Q L T ED + + + + +
Sbjct: 885 CLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQ 944
Query: 744 TLSKQRE 750
L KQRE
Sbjct: 945 ELQKQRE 951
Score = 55.1 bits (131), Expect = 2e-07
Identities = 111/591 (18%), Positives = 244/591 (41%), Gaps = 86/591 (14%)
Query: 5 ELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTF 64
+L+G +K ++ K + L+K + + + EQ + +L++ QQ + T
Sbjct: 864 QLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETI 923
Query: 65 RNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQE--QKSVFDEDL--QKKIEENE 120
RN +L L+ +++ E +K ++S + +E + + + DL QK IE
Sbjct: 924 RNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTG 983
Query: 121 RLHIQFFEADEQHKHVEAELRSRLATLETEA---AQHQAVVDGLTRKYMETIEKLQNDKA 177
E D Q+K +++ + L+ + A H + +D + + +EK N
Sbjct: 984 TARQVKIEMD-QYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVK 1042
Query: 178 KLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSG---RLEESLSIINEKVPFNDTKYS 234
+LE + E E E + E + +L+ H +L +L+E ++ + + KY+
Sbjct: 1043 ELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYT 1102
Query: 235 QYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAIDTIS 294
L L + +++ +++ ++ +D A+ +
Sbjct: 1103 TIKDLTAELRECKMEIE--------------------------DKKQELLEMDQALKERN 1136
Query: 295 -PLNQKFSQYLHENAS---YVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSYI 350
L Q+ +Q H + + + +E+ ++ L ++ + + + E ++++ ++ L +
Sbjct: 1137 WELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAK 1196
Query: 351 CFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPST 410
LR+ L++ +E S L+ Q MK+M +V ++ + YIA
Sbjct: 1197 EQLREKEFIMLQNEQE-------ISQLKKEIERTQQRMKEMESVMKEQEQYIA------- 1242
Query: 411 EPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCIL 470
T Y + ++G L + + +++ A H+ A +++ L
Sbjct: 1243 -------TQYKEAI-DLGQEL---RLTREQVQNSHTELAEARHQQVQAQREIER-----L 1286
Query: 471 SSVVALTNGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYK-KKAAAYMK 529
SS + K N+L + + + E +Q + KK +A ++
Sbjct: 1287 SSELEDMKQLSKEKDAHGNHL---------AEELGASKVREAHLEARMQAEIKKLSAEVE 1337
Query: 530 SLRKPL-LESVPYEEALANRRILLSSTESREGLAQQVQQSLEKISKLEQEK 579
SL++ +E + ++E A +I S +S++ QQ+ + LEK +KLE E+
Sbjct: 1338 SLKEAYHMEMISHQENHAKWKI---SADSQKSSVQQLNEQLEK-AKLELEE 1384
Score = 50.4 bits (119), Expect = 6e-06
Identities = 151/801 (18%), Positives = 316/801 (39%), Gaps = 107/801 (13%)
Query: 11 QKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLA 70
++L + ++ A+N LK + + ++E+L K + KL+ EM + L L
Sbjct: 644 EELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLE 703
Query: 71 KRVE--------LLQDELALSEPRGKKNKKSGESSSQLSQEQKSV---FDEDLQKKIEEN 119
K++E + L + +KN+K + ++ E + + F++ + +E++
Sbjct: 704 KQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQH 763
Query: 120 -------ERLHIQFFEADEQHKHVEAEL----------RSRLATLETEAAQHQAVVDGLT 162
ERL Q + D+Q K E + + L +L+ + + +
Sbjct: 764 KEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKEN 823
Query: 163 RKYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLH------EDLSGRLE 216
K E ++ LQN ++ +K + L+ + C+ EE L L L E +
Sbjct: 824 MKKDEALKALQNQVSEETIKVRQLDSALEICK---EELVLHLNQLEGNKEKFEKQLKKKS 880
Query: 217 ESLSIINEKVPFNDTKYSQYNALNVPL-HNRRHQLKMRDIAGQALAFVQDLVTALLNFHT 275
E + + +++ + + + NV L H + Q +M ++D T L +
Sbjct: 881 EEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVS 940
Query: 276 YTEQRIQIFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLET 335
EQ +Q +S+ + + + +K HE A R + + E T T +
Sbjct: 941 KLEQELQ-KQRESSAEKLRKMEEKCESAAHE-ADLKR----------QKVIELTGTARQV 988
Query: 336 TVKLKTFSEHLTSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDM------K 389
+++ + E L+ + ++ L+ + E+ A+ L++ D K
Sbjct: 989 KIEMDQYKEELSK--------MEKEIMHLKRDGEN----KAMHLSQLDMILDQTKTELEK 1036
Query: 390 KMTAV--FEKLQTYIALLALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQ 447
K AV EKLQ + + +L T + + + L + ++D+ Q
Sbjct: 1037 KTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQE-LRDV----LQ 1091
Query: 448 KAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKAASG 507
KA + E T K +T + + + + ++ +D + ++ K +
Sbjct: 1092 KAQLSLEEKYTTIKDLTAE--LRECKMEIEDKKQELL-----EMDQALKERNWELKQRAA 1144
Query: 508 FISPLS---AECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLSSTESREGLAQQ 564
++ L E + ++K +L K LE + + + L + ++E L ++
Sbjct: 1145 QVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQN--AKEQLREK 1202
Query: 565 ---VQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRIADKLKNT-GSAQLVGLAQENA 620
+ Q+ ++IS+L++E E + + ++++ Q IA + K Q + L +E
Sbjct: 1203 EFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQV 1262
Query: 621 AVSNT----AGQDEATAKAVLEPIQS-TSLVPDVESREDLIKNHYMARIVELTSQLQLAD 675
S+T A + A+ +E + S + + +D NH L +L +
Sbjct: 1263 QNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNH-------LAEELGASK 1315
Query: 676 SKSVHFYAECRALSKRL-ALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYE---DQL 731
+ H A +A K+L A E KEA EM +N ++ + + K S + +QL
Sbjct: 1316 VREAHLEARMQAEIKKLSAEVESLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQL 1375
Query: 732 SMMSDHLCSMNETLSKQREEI 752
L +T+S +++
Sbjct: 1376 EKAKLELEEAQDTVSNLHQQV 1396
Score = 45.8 bits (107), Expect = 1e-04
Identities = 158/758 (20%), Positives = 290/758 (38%), Gaps = 94/758 (12%)
Query: 36 ANSAALKEQLKMKDQSLRKLQQEMDSLT-FRNLQLA---KRVELLQDELALSEPRGKKNK 91
AN A+L+ +LK+ + SL+ L +E+ S++ N A R E L ++ S P G N
Sbjct: 138 ANVASLRHELKITEWSLQSLGEELSSVSPSENSDYAPNPSRSEKLILDVQPSHP-GLLNY 196
Query: 92 KSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEADEQHKHVEAELRSRLATLETEA 151
E+ ++S D QKK +++ D++ K LR +L L +
Sbjct: 197 SPYENVCKISGSST-----DFQKK--PRDKMFSSSAPVDQEIK----SLREKLNKLRQQN 245
Query: 152 AQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHED- 210
A L K+ +L +AK+ + ++ A L + L+ + +D
Sbjct: 246 ACLVTQNHSLMTKFESIHFELTQSRAKVSMLESAQQQAASVPILEEQIINLEAEVSAQDK 305
Query: 211 ----LSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDL 266
+LE+S ++ EK + L V L + Q K +
Sbjct: 306 VLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAE------------ 353
Query: 267 VTALLNFHTYTEQRIQIFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESIT 326
QR + A+ L++ F QY + A + ++ E I
Sbjct: 354 -----------RQR------NEALYNAEELSKAFQQYKKKVAEKLEKVQAE-----EEIL 391
Query: 327 EDTVTVLETTVKLKTFSEHLTSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQ 386
E +T E + K E Y L +IL +L+ L+EE + LR ++ S+
Sbjct: 392 ERNLTNCEK--ENKRLQERCGLYKSEL-EILKEKLRQLKEENNNG--KEKLRIMAVKNSE 446
Query: 387 DMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNVGAALH-GFHDVMKDISKHY 445
M ++T E Q+ + L + + D +LR +S + N + + D+ +
Sbjct: 447 VMAQLT---ESRQSILKLESELENK-DEILRDKFSLMNENRELKVRVAAQNERLDLCQQE 502
Query: 446 SQKAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIA-SFFSNNLDYFIASLSYGPKA 504
+ + +E + +K+I+ + + + K S FSN D I
Sbjct: 503 IESSRVELR---SLEKIISQLP-LKRELFGFKSYLSKYQMSSFSNKEDRCIGCCEANKLV 558
Query: 505 ASGFISPLSAECMLQYKKKAAAYMKSLRKPLLESVPYEEA-----LANRRILLSSTESRE 559
S L+ + K A L + L+ +E+ L + L + E
Sbjct: 559 ISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQESSKLSSLETEPVKLGGHQVAE 618
Query: 560 GLAQQVQQSLEKISKLEQEKEHWMLEAQLAK-IKLEKENQRIADKLKN-TGSAQLVGLAQ 617
+ Q Q ++ K + E+++ +E K I++E EN + + + T QL+
Sbjct: 619 SVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEEL 678
Query: 618 ENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVESREDLIK-NHYMARIVELTSQLQLADS 676
A +++ + E T K S L + + E ++ + A+ EL +L +
Sbjct: 679 LEKASNSSKLESEMTKKC------SQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNE 732
Query: 677 KSVHFYAECRALSKRLALA-EKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMS 735
K +++ LA EK+K+ E+ K + I RL+ +L + +++Q MS
Sbjct: 733 KIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMS 792
Query: 736 ----DHLCSMNETLSKQREEIDTLKMSSKGNSKKNKSR 769
D +C + E +D L SKG KK +
Sbjct: 793 MLQQDIICKQHHL-----ESLDRLLTESKGEMKKENMK 825
Score = 36.6 bits (83), Expect = 0.090
Identities = 148/833 (17%), Positives = 320/833 (38%), Gaps = 123/833 (14%)
Query: 3 SAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSL 62
S Q +K+A++ K++A+ ++L++ + + + + L+E+ + L L++++ L
Sbjct: 367 SKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQL 426
Query: 63 TFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVF---------DEDLQ 113
N +++ ++ K+ E +QL++ ++S+ DE L+
Sbjct: 427 KEENNNGKEKLRIMA-------------VKNSEVMAQLTESRQSILKLESELENKDEILR 473
Query: 114 KK---IEENERLHIQFFEADEQHKHVEAELR-SRLATLETEAAQHQAVVDGLTRKYMETI 169
K + EN L ++ +E+ + E+ SR+ E Q + + +
Sbjct: 474 DKFSLMNENRELKVRVAAQNERLDLCQQEIESSRVELRSLEKIISQLPLKRELFGFKSYL 533
Query: 170 EKLQ-----NDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSG-RLEESLSIIN 223
K Q N + + + + E R++ + +++ LH +L+ +L +SL N
Sbjct: 534 SKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCN 593
Query: 224 EKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQI 283
+ +K S V L + ++D N HT +Q +
Sbjct: 594 DSQ--ESSKLSSLETEPVKLGGHQVAESVKD----------------QNQHTMNKQYEK- 634
Query: 284 FPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHL---FESITEDTVTVLETTVKL- 339
+ I L K Q EN+ L+ M H F+ I E+ + + KL
Sbjct: 635 -ERQRLVTGIEELRTKLIQIEAENSD----LKVNMAHRTSQFQLIQEELLEKASNSSKLE 689
Query: 340 ----KTFSEHLTSYICFLRKILPY-------------------QLKSLEEECESS---LC 373
K S+ LT KI+ Y +++SLE + +C
Sbjct: 690 SEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKIC 749
Query: 374 TSALRARNLELSQDMKKMTAVFEKLQTYIALL---------ALPSTEPDGLLRTNYSSVL 424
+ +A+ + L Q K+M E+L+ + + + D + + ++ L
Sbjct: 750 LAFEKAKKIHLEQH-KEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESL 808
Query: 425 TNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIA 484
+ G ++ K+ K A+++++ T K+ + + L ++
Sbjct: 809 DRLLTESKG--EMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQL- 865
Query: 485 SFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAAYMKSLRKPLLESVPYEEA 544
N + F L +E + +K+ SL++ ++V +
Sbjct: 866 ---EGNKEKFEKQLKK------------KSEEVYCLQKELKIKNHSLQETSEQNVILQHT 910
Query: 545 LANRRILLSSTESREGLAQQVQQSLEK-ISKLEQE--KEHWMLEAQLAKIKLEKENQRIA 601
L ++ +L R G + Q LEK +SKLEQE K+ +L K++ + E+
Sbjct: 911 LQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHE 970
Query: 602 DKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVE-SREDLIKNHY 660
LK +L G A++ + ++ + + + ++ + S+ D+I +
Sbjct: 971 ADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQT 1030
Query: 661 MARIVELTSQLQLADSKSVHFYAE-CRALSKRLALAEKSKEALTEEMKLASQNISRLQDE 719
+ + T+ ++ + E AL KR L + + A E+K + + L+D
Sbjct: 1031 KTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNA-HGELKSTLRQLQELRDV 1089
Query: 720 LTTTKRSYEDQLSMMSDHLCSMNE---TLSKQREEIDTLKMSSKGNSKKNKSR 769
L + S E++ + + D + E + +++E+ + + K + + K R
Sbjct: 1090 LQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQR 1142
Score = 34.3 bits (77), Expect = 0.45
Identities = 49/233 (21%), Positives = 102/233 (43%), Gaps = 29/233 (12%)
Query: 561 LAQQVQQSLEKISKLEQEKEHWMLEAQL--------------AKIKLEKENQRIAD---- 602
L +Q + S EK+ K+E++ E EA L KI++++ + ++
Sbjct: 946 LQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKE 1005
Query: 603 --KLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAV--LEPIQ---STSLVPDVESREDL 655
LK G + + L+Q + + T + E AV LE +Q T L ++ RE +
Sbjct: 1006 IMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKRE-V 1064
Query: 656 IKNHYMARIVELTSQL-QLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNIS 714
++ EL S L QL + + V A+ K + + + E +M++ +
Sbjct: 1065 LETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQE 1124
Query: 715 RLQDELTTTKRSYEDQLSMMSDHLCSMNETLSKQREEIDTLKMSSKGNSKKNK 767
L+ + +R++E L + + ++ T+ + R E++ + +G +K++
Sbjct: 1125 LLEMDQALKERNWE--LKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSE 1175
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 64.3 bits (155), Expect = 4e-10
Identities = 175/869 (20%), Positives = 343/869 (39%), Gaps = 121/869 (13%)
Query: 5 ELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTF 64
E + + Q+L E K+ Q L++ + +E+A L+ + + ++KL+ E+ +
Sbjct: 940 EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDD 999
Query: 65 RNLQLAKRVELLQDELA---------------LSEPRGKKNKKSGESSSQLSQEQKSVFD 109
+N +L+K +LL++ ++ L++ + K E +L +E+KS +
Sbjct: 1000 QNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQE 1059
Query: 110 -EDLQKKIEENER--------LHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDG 160
E L++K+E + L Q E Q E EL++ LA L+ E AQ +
Sbjct: 1060 LEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKK 1119
Query: 161 LTRKYMETIEKLQNDKAKLEVKSQTLEKEAKEC-----RLRTE-ECQLQLKTLHEDLSGR 214
+ R+ I LQ D EK+ ++ L+TE E L ++L +
Sbjct: 1120 I-RELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAK 1178
Query: 215 LEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFH 274
E+ ++++ + + D + + A V ++H + ++ Q F + N
Sbjct: 1179 REQEVTVLKKAL---DEETRSHEA-QVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1234
Query: 275 TYTEQRI----QIFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITE--- 327
T ++ ++ + A + +K + E S E L + + +
Sbjct: 1235 TLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1294
Query: 328 --DTVTVLETTVKLKTFSEHLTSYICFLRKILPYQLKSLEEECESSLCTSALRARNLE-- 383
++VT + + K L + L L + L+EE L S + R LE
Sbjct: 1295 EVESVTGMLNEAEGKAIK--LAKDVASLSSQLQDTQELLQEETRQKLNVST-KLRQLEEE 1351
Query: 384 ---LSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKD 440
L + + + L+ +I+ L + ++ L+ +++S + + F +++
Sbjct: 1352 RNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEIEN 1410
Query: 441 ISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNNLDYFIASLSY 500
+++ Y +KAA +L +L D + VV L N ++ S F L+
Sbjct: 1411 LTQQYEEKAAAYDKLEKTKNRLQQELDDL---VVDLDN-QRQLVSNLEKKQRKFDQLLAE 1466
Query: 501 GPKAASGFISPLS-AECMLQYKKKAAAYMKSLRKPLLESVPYEEAL-ANRRILLSSTESR 558
+S + AE + K+ A SL + L E++ +E L ++L + E
Sbjct: 1467 EKNISSKYADERDRAEAEAREKETKAL---SLARALEEALEAKEELERTNKMLKAEMEDL 1523
Query: 559 EGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRIAD----------KLKNTG 608
V +++ ++ K ++ E M E + +LE E Q D LK
Sbjct: 1524 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1583
Query: 609 SAQLVGLAQENAAVS----------NTAGQDE-------ATAKAVLE-PIQSTSLVPD-- 648
L ++N T +DE A AK LE ++ L D
Sbjct: 1584 ERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSA 1643
Query: 649 VESREDLIK--NHYMARIVELTSQLQLA--------------DSKSVHFYAECRALSKRL 692
++ RE+ IK A++ + +L+ A + K+ A+ L + L
Sbjct: 1644 IKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1703
Query: 693 ALAEKS-------KEALTEEMKLASQNISRLQDE---LTTTKRSYEDQLSMMSDHLCSMN 742
A AE++ KE L EE+ + + LQDE L E++L ++ +M+
Sbjct: 1704 AAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMS 1763
Query: 743 ETLSK---QREEIDTLKMSSKGNSKKNKS 768
+ + K Q E++ + + ++KN+S
Sbjct: 1764 DRVRKATQQAEQLSNELATERSTAQKNES 1792
Score = 63.9 bits (154), Expect = 5e-10
Identities = 145/740 (19%), Positives = 284/740 (38%), Gaps = 87/740 (11%)
Query: 3 SAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSL 62
+A+L G+ + L Q ++ + + L+ V + Q+ + + + + KLQ E++S+
Sbjct: 1240 NADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV 1299
Query: 63 TF-------RNLQLAKRV----ELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDE- 110
T + ++LAK V LQD L + ++ QL +E+ S+ D+
Sbjct: 1300 TGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQL 1359
Query: 111 DLQKKIEENERLHIQFFEAD-EQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYME-- 167
D + + ++N HI K + S + LE + Q ++ LT++Y E
Sbjct: 1360 DEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKA 1419
Query: 168 -TIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKV 226
+KL+ K +L Q +L L DL + + ++ ++
Sbjct: 1420 AAYDKLEKTKNRL---------------------QQELDDLVVDLDNQRQLVSNLEKKQR 1458
Query: 227 PFNDTKYSQYNALNVPLHNR-RHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFP 285
F+ + N + R R + + R+ +AL+ + L AL E
Sbjct: 1459 KFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEAL---EAKEELERTNKM 1515
Query: 286 VDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEH 345
+ + ++ + + +HE R LE M + + E+ L+ T K
Sbjct: 1516 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQL-EELEDELQATEDAKL---R 1571
Query: 346 LTSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALL 405
L + L+ L++ +E+ E + +L + + + E + AL
Sbjct: 1572 LEVNMQALKGQFERDLQARDEQNEE---------KRRQLQRQLHEYETELEDERKQRALA 1622
Query: 406 ALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITT 465
A + +G L+ + +A+ G + +K + K +Q + EL A
Sbjct: 1623 AAAKKKLEGDLK----DLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR--- 1675
Query: 466 NDCILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKA-----------ASGFISPLSA 514
+ A K A +L L+ +A A S LS
Sbjct: 1676 -----DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSG 1730
Query: 515 ECMLQ-YKKKAAAYMKSLRKPLLESVPYEEALANRRILLSSTESREGLAQQVQQSLEKIS 573
LQ K++ A + L + L E EA+++R + +T+ E L+ ++
Sbjct: 1731 RNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR--VRKATQQAEQLSNELATERSTAQ 1788
Query: 574 KLEQEKEHWMLEAQLAKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATA 633
K E ++ + + + KL + + K K+T +A +AQ V A + +A
Sbjct: 1789 KNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAAT 1848
Query: 634 KAVLEPIQSTS-LVPDVESREDLIKNHYM------ARIVELTSQLQLADSKSVHFYAECR 686
K++ + + ++ VE + + + AR+ +L QL+ A+ +S A R
Sbjct: 1849 KSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRR 1908
Query: 687 ALSKRLALAEKSKEALTEEM 706
L + L A +S EA+ E+
Sbjct: 1909 KLQRELDEATESNEAMGREV 1928
Score = 46.2 bits (108), Expect = 1e-04
Identities = 57/249 (22%), Positives = 109/249 (43%), Gaps = 45/249 (18%)
Query: 19 KLRAQNQVLKKGVVDEQANSAA-----------LKEQLKMKDQSLRKLQQEMDSLTFRNL 67
+ R Q + K+ + +E A+S + L+ ++ ++ L + Q M++++ R
Sbjct: 1708 RARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR 1767
Query: 68 QLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFF 127
+ ++ E L +ELA +KN ES+ Q + Q +++L+ K+ E E
Sbjct: 1768 KATQQAEQLSNELATERSTAQKN----ESARQQLERQ----NKELRSKLHEMEGA----- 1814
Query: 128 EADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKL-QNDKAKLEVKSQTL 186
V+++ +S +A LE + AQ + V+ R+ + L Q DK E+ Q
Sbjct: 1815 --------VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVE 1866
Query: 187 E--KEAKECRLRTEECQLQLKTLHEDLSGRLEESLSI----------INEKVPFNDTKYS 234
+ K A++ + + E+ ++K L L EES I ++E N+
Sbjct: 1867 DERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGR 1926
Query: 235 QYNALNVPL 243
+ NAL L
Sbjct: 1927 EVNALKSKL 1935
Score = 40.8 bits (94), Expect = 0.005
Identities = 54/243 (22%), Positives = 100/243 (41%), Gaps = 27/243 (11%)
Query: 512 LSAECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLSSTESREGLAQQVQQSLEK 571
L AE L + + + +K LE + +E + + E E QQ+Q +K
Sbjct: 903 LQAETELYAEAEEMRVRLAAKKQELEEILHE--------MEARLEEEEDRGQQLQAERKK 954
Query: 572 ISKLEQEKEHWMLEAQLAKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEA 631
+++ + E + E + A+ KL+ E K T A++ L E + + +
Sbjct: 955 MAQQMLDLEEQLEEEEAARQKLQLE--------KVTAEAKIKKLEDEILVMDDQNNKLSK 1006
Query: 632 TAKAVLEPIQ--STSLVPDVESREDL--IKNHYMARIVELTSQLQLADSKSVHFYAECRA 687
K + E I +T+L + E ++L +KN + + I EL +L+ K E
Sbjct: 1007 ERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK----KEEKSRQELEK 1062
Query: 688 LSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSK 747
L ++L E E++ I+ L+ +L + + L+ + D + N L K
Sbjct: 1063 LKRKL---EGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKK 1119
Query: 748 QRE 750
RE
Sbjct: 1120 IRE 1122
Score = 39.3 bits (90), Expect = 0.014
Identities = 163/806 (20%), Positives = 312/806 (38%), Gaps = 123/806 (15%)
Query: 21 RAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQ--- 77
+ Q Q+ V+ Q N AA LK+++ +L ++ L LQ+ ++ E +Q
Sbjct: 815 KRQQQLTAMKVI--QRNCAAY---LKLRNWQWWRLFTKVKPL----LQVTRQEEEMQAKE 865
Query: 78 DELALSEPRGKKN----KKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEADEQH 133
DEL ++ R +K K+ + SQL++E K++ E LQ + E + EA+E
Sbjct: 866 DELQKTKERQQKAENELKELEQKHSQLTEE-KNLLQEQLQAETE-------LYAEAEE-- 915
Query: 134 KHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEAKEC 193
+R RLA + E + ++ + + ++LQ ++ K+ + LE++ +E
Sbjct: 916 ------MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE 969
Query: 194 RLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMR 253
++ QL+ T + +LE+ + +++++ N L R L+ R
Sbjct: 970 EAARQKLQLEKVTAEAKIK-KLEDEILVMDDQ--------------NNKLSKERKLLEER 1014
Query: 254 DIAGQALAFVQDLVTALLNFHTYTEQRIQI-FPVDSAIDTISPLNQKFSQYLHENASYVR 312
+ DL T L + ++ +S I + +K + E R
Sbjct: 1015 ---------ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR 1065
Query: 313 PLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSYIC-----------FLRKI--LPY 359
LE E I + + E ++L E L + + L+KI L
Sbjct: 1066 KLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEG 1125
Query: 360 QLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTN 419
+ L+E+ +S RA + + + + E L+T + L ST LR
Sbjct: 1126 HISDLQEDLDSE------RAARNKAEKQKRDLGEELEALKTELE-DTLDSTATQQELRAK 1178
Query: 420 YSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNG 479
+T + AL ++ H +Q + + A ++L + + L
Sbjct: 1179 REQEVTVLKKALD------EETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKN 1232
Query: 480 AGKIASFFSN------NLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAA------- 526
+ ++ L + + K + L ++C + +A
Sbjct: 1233 KQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKL 1292
Query: 527 --YMKSLRKPLLESVPYEEALANRRILLSS--TESREGLAQQVQQSLEKISKLEQ-EKEH 581
++S+ L E+ LA LSS +++E L ++ +Q L +KL Q E+E
Sbjct: 1293 QNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1352
Query: 582 WMLEAQL-----AKIKLEKE----NQRIADKLK------NTGSAQLVGLAQENAAVSNTA 626
L+ QL AK LE+ N +++D K +T A G + + N
Sbjct: 1353 NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLT 1412
Query: 627 GQDEATAKAVLEPIQSTSLVPDVESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECR 686
Q E A A + ++ T E +DL+ + R +L S L+ K AE +
Sbjct: 1413 QQYEEKA-AAYDKLEKTKNRLQQE-LDDLVVDLDNQR--QLVSNLEKKQRKFDQLLAEEK 1468
Query: 687 ALSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMS---DHLCSMNE 743
+S + A EA E + + +++R +E K E M+ + L S +
Sbjct: 1469 NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD 1528
Query: 744 TLSKQREEIDTLKMSSKGNSKKNKSR 769
+ K E++ K + + ++ K++
Sbjct: 1529 DVGKNVHELEKSKRALETQMEEMKTQ 1554
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 64.3 bits (155), Expect = 4e-10
Identities = 175/869 (20%), Positives = 343/869 (39%), Gaps = 121/869 (13%)
Query: 5 ELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTF 64
E + + Q+L E K+ Q L++ + +E+A L+ + + ++KL+ E+ +
Sbjct: 933 EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDD 992
Query: 65 RNLQLAKRVELLQDELA---------------LSEPRGKKNKKSGESSSQLSQEQKSVFD 109
+N +L+K +LL++ ++ L++ + K E +L +E+KS +
Sbjct: 993 QNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQE 1052
Query: 110 -EDLQKKIEENER--------LHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDG 160
E L++K+E + L Q E Q E EL++ LA L+ E AQ +
Sbjct: 1053 LEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKK 1112
Query: 161 LTRKYMETIEKLQNDKAKLEVKSQTLEKEAKEC-----RLRTE-ECQLQLKTLHEDLSGR 214
+ R+ I LQ D EK+ ++ L+TE E L ++L +
Sbjct: 1113 I-RELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAK 1171
Query: 215 LEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFH 274
E+ ++++ + + D + + A V ++H + ++ Q F + N
Sbjct: 1172 REQEVTVLKKAL---DEETRSHEA-QVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1227
Query: 275 TYTEQRI----QIFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITE--- 327
T ++ ++ + A + +K + E S E L + + +
Sbjct: 1228 TLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1287
Query: 328 --DTVTVLETTVKLKTFSEHLTSYICFLRKILPYQLKSLEEECESSLCTSALRARNLE-- 383
++VT + + K L + L L + L+EE L S + R LE
Sbjct: 1288 EVESVTGMLNEAEGKAIK--LAKDVASLSSQLQDTQELLQEETRQKLNVST-KLRQLEEE 1344
Query: 384 ---LSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKD 440
L + + + L+ +I+ L + ++ L+ +++S + + F +++
Sbjct: 1345 RNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEIEN 1403
Query: 441 ISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNNLDYFIASLSY 500
+++ Y +KAA +L +L D + VV L N ++ S F L+
Sbjct: 1404 LTQQYEEKAAAYDKLEKTKNRLQQELDDL---VVDLDN-QRQLVSNLEKKQRKFDQLLAE 1459
Query: 501 GPKAASGFISPLS-AECMLQYKKKAAAYMKSLRKPLLESVPYEEAL-ANRRILLSSTESR 558
+S + AE + K+ A SL + L E++ +E L ++L + E
Sbjct: 1460 EKNISSKYADERDRAEAEAREKETKAL---SLARALEEALEAKEELERTNKMLKAEMEDL 1516
Query: 559 EGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRIAD----------KLKNTG 608
V +++ ++ K ++ E M E + +LE E Q D LK
Sbjct: 1517 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1576
Query: 609 SAQLVGLAQENAAVS----------NTAGQDE-------ATAKAVLE-PIQSTSLVPD-- 648
L ++N T +DE A AK LE ++ L D
Sbjct: 1577 ERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSA 1636
Query: 649 VESREDLIK--NHYMARIVELTSQLQLA--------------DSKSVHFYAECRALSKRL 692
++ RE+ IK A++ + +L+ A + K+ A+ L + L
Sbjct: 1637 IKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1696
Query: 693 ALAEKS-------KEALTEEMKLASQNISRLQDE---LTTTKRSYEDQLSMMSDHLCSMN 742
A AE++ KE L EE+ + + LQDE L E++L ++ +M+
Sbjct: 1697 AAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMS 1756
Query: 743 ETLSK---QREEIDTLKMSSKGNSKKNKS 768
+ + K Q E++ + + ++KN+S
Sbjct: 1757 DRVRKATQQAEQLSNELATERSTAQKNES 1785
Score = 63.9 bits (154), Expect = 5e-10
Identities = 145/740 (19%), Positives = 284/740 (38%), Gaps = 87/740 (11%)
Query: 3 SAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSL 62
+A+L G+ + L Q ++ + + L+ V + Q+ + + + + KLQ E++S+
Sbjct: 1233 NADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV 1292
Query: 63 TF-------RNLQLAKRV----ELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDE- 110
T + ++LAK V LQD L + ++ QL +E+ S+ D+
Sbjct: 1293 TGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQL 1352
Query: 111 DLQKKIEENERLHIQFFEAD-EQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYME-- 167
D + + ++N HI K + S + LE + Q ++ LT++Y E
Sbjct: 1353 DEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKA 1412
Query: 168 -TIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKV 226
+KL+ K +L Q +L L DL + + ++ ++
Sbjct: 1413 AAYDKLEKTKNRL---------------------QQELDDLVVDLDNQRQLVSNLEKKQR 1451
Query: 227 PFNDTKYSQYNALNVPLHNR-RHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFP 285
F+ + N + R R + + R+ +AL+ + L AL E
Sbjct: 1452 KFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEAL---EAKEELERTNKM 1508
Query: 286 VDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEH 345
+ + ++ + + +HE R LE M + + E+ L+ T K
Sbjct: 1509 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQL-EELEDELQATEDAKL---R 1564
Query: 346 LTSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALL 405
L + L+ L++ +E+ E + +L + + + E + AL
Sbjct: 1565 LEVNMQALKGQFERDLQARDEQNEE---------KRRQLQRQLHEYETELEDERKQRALA 1615
Query: 406 ALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITT 465
A + +G L+ + +A+ G + +K + K +Q + EL A
Sbjct: 1616 AAAKKKLEGDLK----DLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR--- 1668
Query: 466 NDCILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKA-----------ASGFISPLSA 514
+ A K A +L L+ +A A S LS
Sbjct: 1669 -----DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSG 1723
Query: 515 ECMLQ-YKKKAAAYMKSLRKPLLESVPYEEALANRRILLSSTESREGLAQQVQQSLEKIS 573
LQ K++ A + L + L E EA+++R + +T+ E L+ ++
Sbjct: 1724 RNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR--VRKATQQAEQLSNELATERSTAQ 1781
Query: 574 KLEQEKEHWMLEAQLAKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATA 633
K E ++ + + + KL + + K K+T +A +AQ V A + +A
Sbjct: 1782 KNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAAT 1841
Query: 634 KAVLEPIQSTS-LVPDVESREDLIKNHYM------ARIVELTSQLQLADSKSVHFYAECR 686
K++ + + ++ VE + + + AR+ +L QL+ A+ +S A R
Sbjct: 1842 KSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRR 1901
Query: 687 ALSKRLALAEKSKEALTEEM 706
L + L A +S EA+ E+
Sbjct: 1902 KLQRELDEATESNEAMGREV 1921
Score = 46.2 bits (108), Expect = 1e-04
Identities = 57/249 (22%), Positives = 109/249 (43%), Gaps = 45/249 (18%)
Query: 19 KLRAQNQVLKKGVVDEQANSAA-----------LKEQLKMKDQSLRKLQQEMDSLTFRNL 67
+ R Q + K+ + +E A+S + L+ ++ ++ L + Q M++++ R
Sbjct: 1701 RARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR 1760
Query: 68 QLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFF 127
+ ++ E L +ELA +KN ES+ Q + Q +++L+ K+ E E
Sbjct: 1761 KATQQAEQLSNELATERSTAQKN----ESARQQLERQ----NKELRSKLHEMEGA----- 1807
Query: 128 EADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKL-QNDKAKLEVKSQTL 186
V+++ +S +A LE + AQ + V+ R+ + L Q DK E+ Q
Sbjct: 1808 --------VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVE 1859
Query: 187 E--KEAKECRLRTEECQLQLKTLHEDLSGRLEESLSI----------INEKVPFNDTKYS 234
+ K A++ + + E+ ++K L L EES I ++E N+
Sbjct: 1860 DERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGR 1919
Query: 235 QYNALNVPL 243
+ NAL L
Sbjct: 1920 EVNALKSKL 1928
Score = 40.8 bits (94), Expect = 0.005
Identities = 54/243 (22%), Positives = 100/243 (41%), Gaps = 27/243 (11%)
Query: 512 LSAECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLSSTESREGLAQQVQQSLEK 571
L AE L + + + +K LE + +E + + E E QQ+Q +K
Sbjct: 896 LQAETELYAEAEEMRVRLAAKKQELEEILHE--------MEARLEEEEDRGQQLQAERKK 947
Query: 572 ISKLEQEKEHWMLEAQLAKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEA 631
+++ + E + E + A+ KL+ E K T A++ L E + + +
Sbjct: 948 MAQQMLDLEEQLEEEEAARQKLQLE--------KVTAEAKIKKLEDEILVMDDQNNKLSK 999
Query: 632 TAKAVLEPIQ--STSLVPDVESREDL--IKNHYMARIVELTSQLQLADSKSVHFYAECRA 687
K + E I +T+L + E ++L +KN + + I EL +L+ K E
Sbjct: 1000 ERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK----KEEKSRQELEK 1055
Query: 688 LSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSK 747
L ++L E E++ I+ L+ +L + + L+ + D + N L K
Sbjct: 1056 LKRKL---EGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKK 1112
Query: 748 QRE 750
RE
Sbjct: 1113 IRE 1115
Score = 39.3 bits (90), Expect = 0.014
Identities = 163/806 (20%), Positives = 312/806 (38%), Gaps = 123/806 (15%)
Query: 21 RAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQ--- 77
+ Q Q+ V+ Q N AA LK+++ +L ++ L LQ+ ++ E +Q
Sbjct: 808 KRQQQLTAMKVI--QRNCAAY---LKLRNWQWWRLFTKVKPL----LQVTRQEEEMQAKE 858
Query: 78 DELALSEPRGKKN----KKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEADEQH 133
DEL ++ R +K K+ + SQL++E K++ E LQ + E + EA+E
Sbjct: 859 DELQKTKERQQKAENELKELEQKHSQLTEE-KNLLQEQLQAETE-------LYAEAEE-- 908
Query: 134 KHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEAKEC 193
+R RLA + E + ++ + + ++LQ ++ K+ + LE++ +E
Sbjct: 909 ------MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE 962
Query: 194 RLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMR 253
++ QL+ T + +LE+ + +++++ N L R L+ R
Sbjct: 963 EAARQKLQLEKVTAEAKIK-KLEDEILVMDDQ--------------NNKLSKERKLLEER 1007
Query: 254 DIAGQALAFVQDLVTALLNFHTYTEQRIQI-FPVDSAIDTISPLNQKFSQYLHENASYVR 312
+ DL T L + ++ +S I + +K + E R
Sbjct: 1008 ---------ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR 1058
Query: 313 PLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSYIC-----------FLRKI--LPY 359
LE E I + + E ++L E L + + L+KI L
Sbjct: 1059 KLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEG 1118
Query: 360 QLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTN 419
+ L+E+ +S RA + + + + E L+T + L ST LR
Sbjct: 1119 HISDLQEDLDSE------RAARNKAEKQKRDLGEELEALKTELE-DTLDSTATQQELRAK 1171
Query: 420 YSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNG 479
+T + AL ++ H +Q + + A ++L + + L
Sbjct: 1172 REQEVTVLKKALD------EETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKN 1225
Query: 480 AGKIASFFSN------NLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAA------- 526
+ ++ L + + K + L ++C + +A
Sbjct: 1226 KQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKL 1285
Query: 527 --YMKSLRKPLLESVPYEEALANRRILLSS--TESREGLAQQVQQSLEKISKLEQ-EKEH 581
++S+ L E+ LA LSS +++E L ++ +Q L +KL Q E+E
Sbjct: 1286 QNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1345
Query: 582 WMLEAQL-----AKIKLEKE----NQRIADKLK------NTGSAQLVGLAQENAAVSNTA 626
L+ QL AK LE+ N +++D K +T A G + + N
Sbjct: 1346 NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLT 1405
Query: 627 GQDEATAKAVLEPIQSTSLVPDVESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECR 686
Q E A A + ++ T E +DL+ + R +L S L+ K AE +
Sbjct: 1406 QQYEEKA-AAYDKLEKTKNRLQQE-LDDLVVDLDNQR--QLVSNLEKKQRKFDQLLAEEK 1461
Query: 687 ALSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMS---DHLCSMNE 743
+S + A EA E + + +++R +E K E M+ + L S +
Sbjct: 1462 NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD 1521
Query: 744 TLSKQREEIDTLKMSSKGNSKKNKSR 769
+ K E++ K + + ++ K++
Sbjct: 1522 DVGKNVHELEKSKRALETQMEEMKTQ 1547
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 63.9 bits (154), Expect = 5e-10
Identities = 170/833 (20%), Positives = 330/833 (39%), Gaps = 122/833 (14%)
Query: 11 QKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLA 70
++L E L +N++L+K + + LK+ + + L+QE L N +L
Sbjct: 628 EELENELHHLEKENELLQKKITN-----------LKITCEKIEALEQENSELERENRKLK 676
Query: 71 KRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQ--------KKIE-ENER 121
K ++ ++ E K+N + E + +L + +S+ ++ K++E E E+
Sbjct: 677 KTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQ 736
Query: 122 LHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEV 181
L K E L L+ E + Q ++ +K I++L+++ LE+
Sbjct: 737 LKKGLELLKASFKKTE-RLEVSYQGLDIENQRLQKTLENSNKK----IQQLESELQDLEM 791
Query: 182 KSQTLEKEAKECRL---RTEECQLQLKTLHEDLS------GRLEESLSIINEKVPFNDTK 232
++QTL+K +E ++ R E+ + + K+L ++ S +LE+ + ++ DT
Sbjct: 792 ENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTT 851
Query: 233 YSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAIDT 292
+ NV + N + K + + ++ L ++ ++ +D I T
Sbjct: 852 LEEN---NVKIGNLEKENK---TLSKEIGIYKESCVRLKELEKENKELVKRATID--IKT 903
Query: 293 ISPLNQ-------KFSQYLHENASYVRPLE------EGMLHLFESITEDTVTVLETTVKL 339
+ L + K Q ++ LE E +LH +S + +LE+ ++
Sbjct: 904 LVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLE- 962
Query: 340 KTFSEHLTSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKL- 398
T + L +I ++ +LE E S N +L Q++K + +E L
Sbjct: 963 STLKKSL--------EIKEEKIAALEARLEES------TNYNQQLRQELKTVKKNYEALK 1008
Query: 399 QTYIALLALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTA 458
Q + S+ P + L D + ++ ++ + A + L T
Sbjct: 1009 QRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQ 1068
Query: 459 TQKLITTNDCILSSVVAL-----------TNGAGKIASFFSNNLDYFIASLSYGPKAASG 507
++L T N+ + + ++AL T + A N S S + A
Sbjct: 1069 LKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQL 1128
Query: 508 FISPLSAECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRIL-LSSTESREGLAQQVQ 566
I S E + K +KSL L++ E L R+ S S+ G +
Sbjct: 1129 LIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAH 1188
Query: 567 QSLE-KISKLEQE-----KEHWMLEAQLAKIKLEKENQRIADKLKNTGSAQLVGLAQENA 620
++LE + LE K+ LE +K+E+E + +K T +A+ L EN
Sbjct: 1189 KNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGEND 1248
Query: 621 AVSNTAGQDEATAKAVLEPIQSTSLVPDVESREDLIKNHYM------ARIVELTSQLQLA 674
+++T Q +L+ ++ L D ++ + L+ N + A +L Q Q
Sbjct: 1249 RLNHTYSQ-------LLK--ETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQL 1299
Query: 675 DSKSVHFYAECRALSK-RLALAEKSKEALTEEMKLASQNISRLQDELTT------TKRSY 727
D S +C LS+ + L E+++ L + L QN + L+ + + +R Y
Sbjct: 1300 DITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQY 1359
Query: 728 EDQLSMMSDHLCSMNETLSKQREEID-----------TLKMSSKGNSKKNKSR 769
D+L+ + + E + Q + D TLKM SKK+ +R
Sbjct: 1360 IDKLNELRRQKEKLEEKIMDQYKFYDPSPPRRRGNWITLKMRKLIKSKKDINR 1412
Score = 49.7 bits (117), Expect = 1e-05
Identities = 145/750 (19%), Positives = 292/750 (38%), Gaps = 88/750 (11%)
Query: 41 LKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQL 100
L +L +R+L+QE++ T + L + +E ++ EL + S+
Sbjct: 249 LSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMY 308
Query: 101 SQE-----QKSVFDEDLQKKIEE-NERLH-IQFFEADEQHKHVEAELRSRLATLETEAAQ 153
E +K+V + L+ ++ ERLH I+F++A VE LET+
Sbjct: 309 RDELDALREKAVRVDKLESEVSRYKERLHDIEFYKA-----RVEELKEDNQVLLETKTML 363
Query: 154 HQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSG 213
+ TR + + +L+ + +L+ K +E E R + EE + TL
Sbjct: 364 EDQLEG--TRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQ 421
Query: 214 RLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNF 273
++ESL + E + T P + H+ + ++ L ++ +L
Sbjct: 422 SMDESLHLGWELEQISRTS----ELSEAPQKSLGHE--VNELTSSRLLKLEMENQSLTK- 474
Query: 274 HTYTEQRIQIFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVL 333
T E R + V+ I + +K +Q L + V LE ++ +S+ ++ +
Sbjct: 475 -TVEELRTTVDSVEGNASKILKM-EKENQRLSKK---VEILENEIVQEKQSL-QNCQNLS 528
Query: 334 ETTVKLKTFSEHLTSYICFLRKILPYQLKSLEEECES-SLCTSALRARNLELSQDMKKMT 392
+ +K K L I LR+ Q+K LE+E E + S+LR R+ ++S + +
Sbjct: 529 KDLMKEKA---QLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRS-QISAEARVKD 584
Query: 393 AVFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIE 452
E + +L + + + + K++ +HY +K
Sbjct: 585 IEKE----------------NKILHESIKETSSKLSKIEFEKRQIKKEL-EHYKEKGERA 627
Query: 453 HELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNN-------------LDYFIASLS 499
EL L N+ + + L KI + N LD F +L+
Sbjct: 628 EELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSF-KNLT 686
Query: 500 YGPKAASGFISPLSAECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLSSTESRE 559
+ ++ S L E + + + S++ L+ L N+ + + ++
Sbjct: 687 FQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQ-------LENKELESEKEQLKK 739
Query: 560 GLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRIADKLKNTGSAQLVGLAQEN 619
GL + ++ S +K +LE + +E Q + LE N++I ++L L EN
Sbjct: 740 GL-ELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQL-----ESELQDLEMEN 793
Query: 620 AAVSNTAGQDEATAKAVLEPIQSTSLVPDVESREDLIKNHYMARIVELTSQLQLADS--- 676
+ + + ++K + + + + S+ + K L Q ++ D+
Sbjct: 794 QTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLE 853
Query: 677 ----KSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLS 732
K + E + LSK + + ++S L E K + + R ++ T ED
Sbjct: 854 ENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLRED--- 910
Query: 733 MMSDHLCS--MNETLSKQREEIDTLKMSSK 760
++S+ L + MN L K E++ + ++ +
Sbjct: 911 LVSEKLKTQQMNNDLEKLTHELEKIGLNKE 940
Score = 49.7 bits (117), Expect = 1e-05
Identities = 138/725 (19%), Positives = 292/725 (40%), Gaps = 111/725 (15%)
Query: 1 MASAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQA---NSAALKEQLKMKDQSLRKLQQ 57
+ + EL+ + ++L + L+A + ++ V Q + L++ L+ ++ +++L+
Sbjct: 725 LENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLES 784
Query: 58 EMDSLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDED----LQ 113
E+ L N L K +E L+ E K+NK + +SQL +++K + E+ Q
Sbjct: 785 ELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Query: 114 KKIEEN--ERLHIQFFEADEQHKHVEAELR------SRLATLETEAAQ--HQAVVDGLTR 163
+I++ E +++ ++++K + E+ RL LE E + +A +D +
Sbjct: 845 AEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATID--IK 902
Query: 164 KYMETIEKLQNDKAKLEVKSQTLEKEA---------KECRLRTEEC--QLQLKTLHEDLS 212
+ E L ++K K + + LEK KE L E+ + K L L
Sbjct: 903 TLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLE 962
Query: 213 GRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLN 272
L++SL I EK+ + + + N L Q+L T N
Sbjct: 963 STLKKSLEIKEEKIAALEARLEESTNYNQQLR-------------------QELKTVKKN 1003
Query: 273 FHTYTEQRIQIFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTV 332
+ +++ + + + + P++ + +++ E+ R L + L E + + T+
Sbjct: 1004 YEALKQRQDE----ERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIE-VERNNATL 1058
Query: 333 ------LETTVK-LKTFSEHLTSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELS 385
L+T +K L+T + +L + I L++ Q SL+E+ + L+ +N +L
Sbjct: 1059 QAEKQALKTQLKQLETQNNNLQAQILALQR----QTVSLQEQ------NTTLQTQNAKLQ 1108
Query: 386 QDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHY 445
+ + + L A L + + L SV+ + ++KD
Sbjct: 1109 VENSTLNSQSTSLMNQNAQLLIQQSS----LENENESVIKEREDLKSLYDSLIKD----- 1159
Query: 446 SQKAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKAA 505
+K + HE + + + + L S A K +L+ L
Sbjct: 1160 HEKLELLHERQASEYESLISKHGTLKS-------AHKNLEVEHRDLEDRYNQL----LKQ 1208
Query: 506 SGFISPLSAECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLSSTESREGLAQQV 565
G + L E ML+ +++ K LLE+ +E A + L + Q+
Sbjct: 1209 KGQLEDL--EKMLKVEQE---------KMLLENKNHETVAAEYKKLCGENDRLNHTYSQL 1257
Query: 566 QQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNT 625
+ E + + + + ++L + +LE E ++ ++ + L + +S
Sbjct: 1258 LKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITS-TKLNNQCELLSQL 1316
Query: 626 AGQDEATAKAVLEPIQS------TSLVPDVESRE--DLIKNHYMARIVELTSQLQLADSK 677
G E + +L+ IQ+ T L ++ES++ + + Y+ ++ EL Q + + K
Sbjct: 1317 KGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEK 1376
Query: 678 SVHFY 682
+ Y
Sbjct: 1377 IMDQY 1381
Score = 44.3 bits (103), Expect = 4e-04
Identities = 50/228 (21%), Positives = 112/228 (49%), Gaps = 28/228 (12%)
Query: 32 VDEQANSAALKEQLKMKDQSLRKLQQEMDS--------------LTFRNLQLAKRVELLQ 77
V+E +S LK L+M++QSL K +E+ + + N +L+K+VE+L+
Sbjct: 454 VNELTSSRLLK--LEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILE 511
Query: 78 DELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEADEQHKHVE 137
+E+ + K++ ++ ++ S+ ++K+ ++ ++ E +ER I+ E + +H +
Sbjct: 512 NEIV----QEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSER-QIKILEQENEHLNQT 566
Query: 138 AELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEA---KECR 194
+ + + EA ++ + E+I++ + +K+E + + ++KE KE
Sbjct: 567 VSSLRQRSQISAEARVKD--IEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKG 624
Query: 195 LRTEECQLQLKTLHE--DLSGRLEESLSIINEKVPFNDTKYSQYNALN 240
R EE + +L L + +L + +L I EK+ + + S+ N
Sbjct: 625 ERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELEREN 672
Score = 34.3 bits (77), Expect = 0.45
Identities = 52/231 (22%), Positives = 94/231 (40%), Gaps = 33/231 (14%)
Query: 555 TESREGLAQQVQQSLEK-ISKLEQEKEHWMLEAQLAKI-KLEKENQRIADKLKNTGSAQL 612
T SR + QSL K + +L + +E +KI K+EKENQR++ K++ +
Sbjct: 458 TSSRLLKLEMENQSLTKTVEELRTTVDS--VEGNASKILKMEKENQRLSKKVEILENE-- 513
Query: 613 VGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVESREDLIKNHYMARIVELTSQLQ 672
+ QE ++ N + K + ++ + + R+ I + + S L+
Sbjct: 514 --IVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLR 571
Query: 673 LADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYE---- 728
S AE R EK + L E +K S +S+++ E K+ E
Sbjct: 572 QRSQIS----AEARVKD-----IEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKE 622
Query: 729 -----DQLSMMSDHLCSMNETLSKQ-------REEIDTLKMSSKGNSKKNK 767
++L HL NE L K+ E+I+ L+ + ++N+
Sbjct: 623 KGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENR 673
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 63.5 bits (153), Expect = 7e-10
Identities = 161/816 (19%), Positives = 329/816 (40%), Gaps = 103/816 (12%)
Query: 4 AELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSL- 62
A+L+ + +++ + +LR Q + ++ +E + + ++ +++ RKL+ EMD
Sbjct: 385 AQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKT---EEARRKLKAEMDEQI 441
Query: 63 -TFRNLQLAKRVELLQDELALSEPRGKKNKKSGESS----SQLSQEQKSVFDEDLQKKIE 117
T +R+ L Q+ + + KKS E +L +++ + +++L KK++
Sbjct: 442 KTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQ 501
Query: 118 ENERLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKA 177
ER E EQ K + +S + E Q +++ +E+L+ K
Sbjct: 502 TRER------EFQEQMKVALEKSQSEYLKISQEKEQQESLA----------LEELELQKK 545
Query: 178 KL----EVKSQTLEKEAKECRLRTEECQLQL-KTLHEDLSGRLEESLSIINEKVPFNDTK 232
+ E K + L++EA+ R R E + L K+L E+ + + ++ + EK N
Sbjct: 546 AILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEI 605
Query: 233 YSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAI-- 290
L + +HQ + Q T + EQ + D I
Sbjct: 606 TVMVEKHKTELESLKHQQDAL-WTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIF 664
Query: 291 -DTISPLNQKFSQYLHENASYVRPLEEGMLHLFES---ITEDTVTVLETTVKLKTFSEHL 346
I +N+K + L + + L + + ++ + E+ + + T K+K + L
Sbjct: 665 QAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMK---QEL 721
Query: 347 TSYICFLRKILPYQLKSLEEECESSL--CTSALRARNLELSQDMKKMTAVFEKLQTYIAL 404
+ + + Q+ S+ +E E S+ AL+ + +L +K+ ++ Q ++
Sbjct: 722 EAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVEN 781
Query: 405 LALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLIT 464
L +G L+ A L F S + Q A E +L QKL+
Sbjct: 782 LEADIKRSEGELQ--------QASAKLDVFQSYQ---SATHEQTKAYEEQLAQLQQKLLD 830
Query: 465 --TNDCILSSVVALTNGAGKIASFF------------------SNNLDYFIASLS--YGP 502
T +L+ VA K ++ ++ + SL+ Y
Sbjct: 831 LETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYES 890
Query: 503 KAASGFISPLSAECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLSSTESREGLA 562
K G + +L K+ M+ +K +E + + + I + + E
Sbjct: 891 KLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFK 950
Query: 563 QQVQQSLEKISKLEQEKEHWM---LEAQLAKIKLEKENQRIADKLKNTG-SAQLVGLAQE 618
Q ++ +EK+ + +E + + L Q AK+K E EN + K +A+++ +AQ
Sbjct: 951 NQ-EKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQA 1009
Query: 619 NAA-VSNTAGQDEATAKAVLEPIQSTSLVPDVESRE--DLI-----KNHYMARIVELTSQ 670
N+A +S+ + E K +E + +V RE D+I K + A ++ +
Sbjct: 1010 NSAGISDAVSRLETNQKEQIESLT------EVHRRELNDVISIWEKKLNQQAEELQEIHE 1063
Query: 671 LQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQ 730
+QL + + E L +++ L KE + +E+ + + QD TT ++Q
Sbjct: 1064 IQLQEKEQ-----EVAELKQKILLFGCEKEEMNKEITWLKEEGVK-QD---TTLNELQEQ 1114
Query: 731 LSMMSDHLCSMNETLSKQREEIDTLKMSSKGNSKKN 766
L S H+ S+ + +K + ++ L++ + K+N
Sbjct: 1115 LKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKEN 1150
Score = 59.7 bits (143), Expect = 1e-08
Identities = 148/763 (19%), Positives = 302/763 (39%), Gaps = 137/763 (17%)
Query: 7 QGKYQKLAQEYSKLRAQNQVLKKGVVDEQANS----AALKEQLKMKDQSLRKLQQEMDSL 62
+GKY +L Y L+ + + L+ + Q S A L+E+L+M Q+ + LQ+E D+
Sbjct: 154 RGKYSELVTAYQMLQREKKKLQGILSQSQDKSLRRIAELREELQMDQQAKKHLQEEFDAS 213
Query: 63 TFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQ--EQKSVFD----------- 109
Q + +LQ +++L + R + + + L Q Q VF
Sbjct: 214 LEEKDQY---ISVLQTQVSLLKQRLRNGPMNVDVLKPLPQLEPQAEVFTKEENPESDGEP 270
Query: 110 -----------EDLQKKIEENERLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVV 158
E LQ++++ E L + E + HK + L T E EA Q Q
Sbjct: 271 VVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKE-----QCTLLTSEKEALQEQ--- 322
Query: 159 DGLTRKYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEES 218
+ ++ +EK+++ + K T ++AK ++ L +D + E+
Sbjct: 323 ---LDERLQELEKIKDLHMAEKTKLITQLRDAKNL----------IEQLEQDKGMVIAET 369
Query: 219 LSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTE 278
++E + + + +Q + + + +L+ + + AF ++L AL E
Sbjct: 370 KRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAF-EELEKALSTAQKTEE 428
Query: 279 QRIQI-FPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTV 337
R ++ +D I TI +++ L + S V+ ++ V V++
Sbjct: 429 ARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVK--------------QEVVDVMK--- 471
Query: 338 KLKTFSEHLTSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEK 397
K+ E + L+K+ +L E+E T L+ R E + MK EK
Sbjct: 472 --KSSEEQIAK----LQKLHEKELARKEQE-----LTKKLQTREREFQEQMK---VALEK 517
Query: 398 LQTYIALLALPSTEPDGL----LRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEH 453
Q+ ++ + + L L ++LT + + D+ ++ + ++ +E
Sbjct: 518 SQSEYLKISQEKEQQESLALEELELQKKAILTE---SENKLRDLQQEAETYRTRILELES 574
Query: 454 ELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLS 513
L + Q+ + + + A N K + + SL + A L
Sbjct: 575 SLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDA-------LW 627
Query: 514 AECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLSS----------------TES 557
E + K++ M+ LR+ + E L ++ I+ +
Sbjct: 628 TEKLQVLKQQYQTEMEKLREKCEQE--KETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTE 685
Query: 558 REGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRIADKLKNTGSAQLVGLAQ 617
E L+ ++ + L+ KLE+E +L+ Q K+K E E + D+ KN Q+ + +
Sbjct: 686 LESLSSELSEVLKARHKLEEELS--VLKDQTDKMKQELEAK--MDEQKNHHQQQVDSIIK 741
Query: 618 ENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVESREDLIKNHYMARIVELTSQLQLADSK 677
E+ + T KA+ + I L+ ++ R+ +K H A + L + ++ ++
Sbjct: 742 EHEV------SIQRTEKALKDQINQLELL--LKERDKHLKEH-QAHVENLEADIKRSE-- 790
Query: 678 SVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDEL 720
E + S +L + + + A E+ K + +++LQ +L
Sbjct: 791 -----GELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKL 828
Score = 58.9 bits (141), Expect = 2e-08
Identities = 147/787 (18%), Positives = 323/787 (41%), Gaps = 108/787 (13%)
Query: 4 AELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMK-DQSLRKLQQEMDSL 62
+EL K + +E+ L++ ++ K + D+ L E+L ++ D +K + +++
Sbjct: 1172 SELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAK 1231
Query: 63 TFRNLQLAK-RVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENER 121
T + ++ + + ++ + R K K++ + S + L++ EE
Sbjct: 1232 TNELINISSSKTNAILSRISHCQHRTTKVKEA----LLIKTCTVSELEAQLRQLTEEQNT 1287
Query: 122 LHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEK---LQNDKAK 178
L+I F +A Q + E +++S A +E+ + +A+ + EK + K +
Sbjct: 1288 LNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKE 1347
Query: 179 LE--VKSQTLEKEA-KECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQ 235
L + + TL KE KE ++ QL DL+ +L+ S+S+ ++ + + Q
Sbjct: 1348 LSENINAVTLMKEELKEKKVEISSLSKQLT----DLNVQLQNSISLSEKEAAISSLR-KQ 1402
Query: 236 YNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAIDTISP 295
Y+ L ++ VQDL T ++++I SA++ +
Sbjct: 1403 YDEEKCELLDQ----------------VQDLS---FKVDTLSKEKI------SALEQVDD 1437
Query: 296 LNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHL---TSYICF 352
+ KFS++ + S T+ TV E ++L+ S+ I
Sbjct: 1438 WSNKFSEWKKKAQS--------------RFTQHQNTVKELQIQLELKSKEAYEKDEQINL 1483
Query: 353 LRKILPYQLKS---LEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPS 409
L++ L Q K L+ E E + NLE ++K TA +L+ +I +
Sbjct: 1484 LKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLET--ELKSQTARIMELEDHITQKTI-- 1539
Query: 410 TEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAI-EHELPTATQKLITTNDC 468
E + L + VL N H + +H+ + ++ + A +K++T +
Sbjct: 1540 -EIESL-----NEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQ 1593
Query: 469 ILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAAYM 528
+ S L ++ +++ + S KA + SA + + K+KA +
Sbjct: 1594 VYSMKAELETKKKEL-----EHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKI 1648
Query: 529 KSLRKPLLESVPYEEALANRRILLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEAQL 588
+++K LL + +E + ++G + + K+ E+E+E +LE +L
Sbjct: 1649 AAIKKQLLSQMEEKEE-----------QYKKGTESHLSELNTKLQ--EREREVHILEEKL 1695
Query: 589 AKIKLEKENQRIADK-LKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVP 647
++ + I + KN + A V T + + + L + L+
Sbjct: 1696 KSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLT--EKEKLLQ 1753
Query: 648 DV-ESREDLIKNH------YMARIVELT-SQLQLADSKSV--HFYAECRALSKRLAL--A 695
V + +E+ + +H Y R+++L ++ + + +S+ H E +K+ +L A
Sbjct: 1754 RVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVA 1813
Query: 696 EKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSKQRE--EID 753
+ ++ + A QN+ + D++ T + E ++ + ++ L +Q+E ++
Sbjct: 1814 QHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVE 1873
Query: 754 TLKMSSK 760
+++SK
Sbjct: 1874 MEELTSK 1880
Score = 52.8 bits (125), Expect = 1e-06
Identities = 145/733 (19%), Positives = 289/733 (39%), Gaps = 117/733 (15%)
Query: 44 QLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQE 103
QL+ K+Q + +L+Q++ ++ K + L++E K++ E QL +
Sbjct: 1065 QLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGV------KQDTTLNELQEQL--K 1116
Query: 104 QKSVFDEDLQKKIEENERLHIQFFEADEQHKHVEAE-LRSRLATLETEAAQHQAVVDGLT 162
QKS L + E + H++ E D E L+ +L L+ A + + V LT
Sbjct: 1117 QKSAHVNSLAQD-ETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELT 1175
Query: 163 RKYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSII 222
K T E+ Q+ K+ E +++LE ++ E + +EE +QL + LE
Sbjct: 1176 SKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAK---T 1232
Query: 223 NEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQ 282
NE + + +K + L+ H + K+++ L+ T +E Q
Sbjct: 1233 NELINISSSKTNA--ILSRISHCQHRTTKVKE-------------ALLIKTCTVSELEAQ 1277
Query: 283 IFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTF 342
+ + +T++ Q+ + L E + ++ ++ + L +TE E + +
Sbjct: 1278 LRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESL---VTEKEALQKEGGNQQQAA 1334
Query: 343 SEHLTSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYI 402
SE S I L+K L + ++ +L L+ + +E+S K++T + +LQ I
Sbjct: 1335 SEK-ESCITQLKKELSENINAV------TLMKEELKEKKVEISSLSKQLTDLNVQLQNSI 1387
Query: 403 ALLALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKL 462
+L +E + + + K Y ++ EL Q L
Sbjct: 1388 SL-----SEKEA----------------------AISSLRKQYDEEKC---ELLDQVQDL 1417
Query: 463 ITTNDCILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYK- 521
D + ++ ++ FS + KA S F + LQ +
Sbjct: 1418 SFKVDTLSKEKISALEQVDDWSNKFS----------EWKKKAQSRFTQHQNTVKELQIQL 1467
Query: 522 --KKAAAYMKSLRKPLLESVPYEEALANRRILLSSTESREGLAQQVQQSLEKISKLEQEK 579
K AY K + LL+ E N+R + L +++ K+ K E
Sbjct: 1468 ELKSKEAYEKDEQINLLKE---ELDQQNKRF--------DCLKGEMEDDKSKMEKKESNL 1516
Query: 580 EHWMLEAQLAKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEP 639
E L++Q A+I +L++ + + + + N + N Q + K +++
Sbjct: 1517 E-TELKSQTARIM----------ELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQK 1565
Query: 640 IQ--------STSLVPDVESREDLIKNHYMARIVELTSQLQLADSKSVHFYA---ECRAL 688
+Q + V + E + ++N + EL ++ + + ++ + E +AL
Sbjct: 1566 LQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKAL 1625
Query: 689 SKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMSD-HLCSMNETLSK 747
R L +S L E + A Q I+ ++ +L + E+Q ++ HL +N L +
Sbjct: 1626 EDR--LESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQE 1683
Query: 748 QREEIDTLKMSSK 760
+ E+ L+ K
Sbjct: 1684 REREVHILEEKLK 1696
Score = 49.3 bits (116), Expect = 1e-05
Identities = 142/785 (18%), Positives = 300/785 (38%), Gaps = 102/785 (12%)
Query: 41 LKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQDEL--ALSEPRGKKNKKSGESSS 98
L++++K ++ L++ ++ + S + L E LQ++L L E K+ E +
Sbjct: 284 LQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTK 343
Query: 99 QLSQ--EQKSVFDEDLQKK---IEENERLHIQFFEADEQHKHVEAELRSRLATLETEAAQ 153
++Q + K++ ++ Q K I E +R Q E E + A+LRSR+ + T+ +
Sbjct: 344 LITQLRDAKNLIEQLEQDKGMVIAETKR---QMHETLEMKEEEIAQLRSRIKQMTTQGEE 400
Query: 154 HQAVVDGLTRKYMETIEKLQND-----------KAKLEVKSQTLEKEAKECRL------- 195
+ + R E +EK + KA+++ + +T+EK ++E R+
Sbjct: 401 LREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELS 460
Query: 196 ------------RTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALNVPL 243
+EE +L+ LHE R E+ L+ +K+ + ++ + + +
Sbjct: 461 RVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELT---KKLQTREREFQEQMKVALEK 517
Query: 244 HNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAI--DTISPLNQKFS 301
+ ++ Q +++L T +E +++ ++ I L
Sbjct: 518 SQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLE 577
Query: 302 QYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHL--------TSYICFL 353
+ L EN + + L +HL + + K KT E L T + L
Sbjct: 578 KSLQENKNQSKDL---AVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVL 634
Query: 354 RKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPD 413
++ +++ L E+CE T L+ + + +++M + + L + TE +
Sbjct: 635 KQQYQTEMEKLREKCEQEKET-LLKDKEIIFQAHIEEMN------EKTLEKLDVKQTELE 687
Query: 414 GLLRTNYSSVLTNVGAALHGFHD---VMKDISKHYSQKAAIEHELPTATQKLITTNDCIL 470
L SS L+ V A H + V+KD + Q+ +E ++ D I+
Sbjct: 688 SL-----SSELSEVLKARHKLEEELSVLKDQTDKMKQE--LEAKMDEQKNHHQQQVDSII 740
Query: 471 SSVVALTNGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAEC------MLQYKKKA 524
K N L+ + K + L A+ + Q K
Sbjct: 741 KEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKL 800
Query: 525 AAYMKSLRKPLLESVPYEEALAN-RRILLSSTESREGLAQQVQQSLEKISKLEQEKEHWM 583
+ ++ YEE LA ++ LL R L +QV + + + E +
Sbjct: 801 DVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHK 860
Query: 584 LEAQLAKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQST 643
++ Q +LEK+N + K+K+ L N T +L+ +
Sbjct: 861 IQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQ 920
Query: 644 S-----LVPDVESRED---LIKNHYMARIVELTSQLQLADSKSVHFYAECR--------A 687
L + ++ED ++ Y + +++ K+ +
Sbjct: 921 KKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAK 980
Query: 688 LSKR-----LALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMSD-HLCSM 741
L K L L++K K+ + +++A N + + D ++ + + ++Q+ +++ H +
Sbjct: 981 LKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRREL 1040
Query: 742 NETLS 746
N+ +S
Sbjct: 1041 NDVIS 1045
Score = 45.1 bits (105), Expect = 3e-04
Identities = 155/837 (18%), Positives = 309/837 (36%), Gaps = 124/837 (14%)
Query: 7 QGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMK-DQSLRKLQQEMDSLTFR 65
Q + + L+ E S++ L++ + + + +K++L+ K D+ QQ++DS+
Sbjct: 683 QTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKE 742
Query: 66 NLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENE----- 120
+ V + + E AL + + E L + Q V E+L+ I+ +E
Sbjct: 743 H-----EVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHV--ENLEADIKRSEGELQQ 795
Query: 121 -RLHIQFFEADEQHKHVE--------AELRSRLATLETEAAQHQAVVDGLTRKYMETIEK 171
+ F++ + H + A+L+ +L LETE V + + + +
Sbjct: 796 ASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTE 855
Query: 172 LQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDT 231
L K +++ Q LEK+ E + + ++ ED + E++ I+ EK
Sbjct: 856 LDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKE----- 910
Query: 232 KYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAID 291
N+ L R Q K +I Q L+ +D + +LN T+ + Q ++
Sbjct: 911 --------NMILQMREGQKKEIEILTQKLSAKEDSI-HILNEEYETKFKNQEKKMEKVKQ 961
Query: 292 TISPLNQKF-SQYLHENASYVRPLEEGMLHLFESITE-----------------DTVTVL 333
+ + + L + A + LE L L + + D V+ L
Sbjct: 962 KAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRL 1021
Query: 334 ETTVK--LKTFSE----HLTSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQD 387
ET K +++ +E L I K L Q + L+E E L EL Q
Sbjct: 1022 ETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQL--QEKEQEVAELKQK 1079
Query: 388 MKKMTAVFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQ 447
+ E++ I L + D L+ + +K S H +
Sbjct: 1080 ILLFGCEKEEMNKEITWLKEEGVKQD---------------TTLNELQEQLKQKSAHVNS 1124
Query: 448 KAAIEHELPTATQKL-------ITTNDCILSSVVAL----TNGAGKIASFFS--NNLDYF 494
A E +L +KL + N + +V L K++ S D
Sbjct: 1125 LAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEE 1184
Query: 495 IASLSYGPKAASGFISPLSAECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLSS 554
SL + ++ + S L++KK + L ++ EA N I +SS
Sbjct: 1185 FQSLKSSHEKSNKSLEDKS----LEFKKLSEELAIQLDICCKKTEALLEAKTNELINISS 1240
Query: 555 TESREGLAQ---------QVQQSLE----KISKLEQEKEHWMLEAQLAKIKLEKENQRIA 601
+++ L++ +V+++L +S+LE + E I ++ ++
Sbjct: 1241 SKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLE 1300
Query: 602 DKLKNTGS--AQLVGLAQENAAVSNTAGQDEATA-----------KAVLEPIQSTSLVPD 648
+K S A + L E A+ G + A K + E I + +L+ +
Sbjct: 1301 EKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKE 1360
Query: 649 VESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKL 708
+ + + ++ +L QLQ S+ + A+S ++ K L ++++
Sbjct: 1361 ELKEKKVEISSLSKQLTDLNVQLQ----NSISLSEKEAAISSLRKQYDEEKCELLDQVQD 1416
Query: 709 ASQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSKQREEIDTLKMSSKGNSKK 765
S + L E + +D + S+ ++ + + L++ + SK+
Sbjct: 1417 LSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKE 1473
Score = 38.1 bits (87), Expect = 0.031
Identities = 39/175 (22%), Positives = 77/175 (44%), Gaps = 7/175 (4%)
Query: 7 QGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQ-LKMKDQSLRKLQQEMDSLTFR 65
Q + +K+ QE L ++ K ++ E A KEQ L+M + QE+++
Sbjct: 1973 QEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLE 2032
Query: 66 NLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQ 125
+ Q + L ++A + K+ K E +E+ + DLQ ++EE ++ + Q
Sbjct: 2033 SHQ--EETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQ 2090
Query: 126 FFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLE 180
E +E + + L+T+ AQ ++ K E E++ N + +L+
Sbjct: 2091 KLEQEENPGNDNVTIME----LQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLK 2141
Score = 32.7 bits (73), Expect = 1.3
Identities = 60/298 (20%), Positives = 121/298 (40%), Gaps = 34/298 (11%)
Query: 489 NNLDYFIASLSYGPKAAS--------GFISPLSAECMLQYKKKAAAYMKSLRKPLLESVP 540
N LD ++ S+ P + G L+ E ++Q ++ + S R E V
Sbjct: 103 NRLDLDSSTASFDPPSDMDSEAEDLVGNSDSLNKEQLIQRLRRMERSLSSYRGKYSELVT 162
Query: 541 YEEALANRRILLSS--TESREGLAQQVQQSLEKISKLEQEKEHWMLE-----------AQ 587
+ L + L ++S++ +++ + E++ +Q K+H E
Sbjct: 163 AYQMLQREKKKLQGILSQSQDKSLRRIAELREELQMDQQAKKHLQEEFDASLEEKDQYIS 222
Query: 588 LAKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVP 647
+ + ++ QR+ + N + + + A V E+ + V+E S +
Sbjct: 223 VLQTQVSLLKQRLRNGPMNVDVLKPLPQLEPQAEVFTKEENPESDGEPVVEDGTSVKTLE 282
Query: 648 DVESR----EDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEA-L 702
++ R E+L+K I Q L S+ + L +RL EK K+ +
Sbjct: 283 TLQQRVKRQENLLKR-CKETIQSHKEQCTLLTSEKEALQEQ---LDERLQELEKIKDLHM 338
Query: 703 TEEMKLASQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSKQREEIDTLKMSSK 760
E+ KL I++L+D ++ +D+ ++++ M+ETL + EEI L+ K
Sbjct: 339 AEKTKL----ITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIK 392
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 62.8 bits (151), Expect = 1e-09
Identities = 135/736 (18%), Positives = 282/736 (38%), Gaps = 76/736 (10%)
Query: 19 KLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQD 78
KL ++ ++ ++D + + ++E+LK K+ L +LQ ++D +LQ K+++ LQ
Sbjct: 1058 KLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQA 1117
Query: 79 ELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEADEQHKHVEA 138
+ E + ++ + ++Q+S +L++ E E E +K EA
Sbjct: 1118 RIEELE----EEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREA 1173
Query: 139 ELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTE 198
E + LE QH+A L +K +++ +L L+ Q LEKE E ++ +
Sbjct: 1174 EFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEID 1233
Query: 199 ECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQ 258
+ ++ L + S +E + + ++ K Q L L+ ++ +L+ ++ G+
Sbjct: 1234 DMASNIEALSKSKS-NIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQN--GE 1290
Query: 259 ALAFVQDLVTALLNFHTYTEQRI--QIFPVDSAIDTISPLNQKFSQYLHEN-------AS 309
V++ +L++ T ++Q + Q+ + ++ + + L +
Sbjct: 1291 LSHRVEE-KESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLRE 1349
Query: 310 YVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSYICFLRKILPYQLKSLEEECE 369
+E L ++++ V + K +T + T + +K L +L+ EE E
Sbjct: 1350 QYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTE 1409
Query: 370 --SSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNV 427
+S C S L L +++ + E+ T A L D +L + L
Sbjct: 1410 TANSKCAS-LEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVL-AEWKQKLDES 1467
Query: 428 GAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIASFF 487
A L + +S + E+ + L N + + LT +IA
Sbjct: 1468 QAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTE---QIAETG 1524
Query: 488 SNNLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAAYMKSLRKPLLESVPYEEALAN 547
N + + KK KS + LE V
Sbjct: 1525 KNLQE-------------------------AEKTKKLVEQEKSDLQVALEEVEGSLEHEE 1559
Query: 548 RRILLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEAQL------AKIKLEKENQRIA 601
+IL E + ++ ++ +EK ++EQ K + A+ A+I+ + R+
Sbjct: 1560 SKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLK 1619
Query: 602 DKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVPD--VESREDLIKNH 659
K++ + + L N ++ T + + V ++ + L D + S ED
Sbjct: 1620 KKMEGDLNEMEIQLGHSNRQMAET----QKHLRTVQGQLKDSQLHLDDALRSNED----- 1670
Query: 660 YMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDE 719
L QL + + ++ E + L E+++ +E+ AS + L +
Sbjct: 1671 -------LKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQ 1723
Query: 720 ---LTTTKRSYEDQLS 732
L TK+ E ++
Sbjct: 1724 NTSLINTKKKLEADIA 1739
Score = 57.0 bits (136), Expect = 6e-08
Identities = 155/814 (19%), Positives = 321/814 (39%), Gaps = 111/814 (13%)
Query: 7 QGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAA-LKEQLKMKDQSLRKLQQEMDSLTFR 65
+ ++QK+ ++ + Q++ + +QA+S A L EQ+ + +KL++E L
Sbjct: 1172 EAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKME 1231
Query: 66 NLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQ 125
+A +E L K+K + E + + ++Q F E K ++ + +H
Sbjct: 1232 IDDMASNIEALS-----------KSKSNIERTCRTVEDQ---FSEIKAKDEQQTQLIHDL 1277
Query: 126 FFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQT 185
+ +A L+++ L + ++++ LT+ ++L+ K ++E +++
Sbjct: 1278 NMQ--------KARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKA 1329
Query: 186 LEKEAKECRLRTEECQLQLKTLHEDLSGR--LEESLSIINEKVPFNDTKYSQYNAL--NV 241
A + +C L + E+ + L+ +LS N +V TKY + +A+
Sbjct: 1330 KNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKY-ETDAIQRTE 1388
Query: 242 PLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQ------IFPVDSAIDTISP 295
L + +L R + + A L T+QR+Q + ++ + +
Sbjct: 1389 ELEEAKKKLAQRLQEAEENTETANSKCASLE---KTKQRLQGEVEDLMRDLERSHTACAT 1445
Query: 296 LNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSYICFLRK 355
L++K + A + + L+E L E+ +++ ++ K++ E + + LR+
Sbjct: 1446 LDKKQRNFDKVLAEWKQKLDESQAEL-EAAQKESRSLSTELFKMRNAYEEVVDQLETLRR 1504
Query: 356 ILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPDGL 415
+ K+L+EE A +NL+ ++ KK+ EK +AL E +G
Sbjct: 1505 ----ENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQ-EKSDLQVAL-----EEVEGS 1554
Query: 416 LRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVVA 475
L S +L V L V ++ + +K +L +Q+ +L + +
Sbjct: 1555 LEHEESKIL-RVQLEL---SQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIR 1610
Query: 476 LTNGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAAYMKSLRKPL 535
N A ++ +L+ L + + AE ++ + +K + L
Sbjct: 1611 SRNDALRLKKKMEGDLNEMEIQLGHSNRQ--------MAETQ-KHLRTVQGQLKDSQLHL 1661
Query: 536 LESVPYEEALANRRILLSSTESREGL----AQQVQQSLEKISKLEQEKEHWMLEAQLAKI 591
+++ E L + L+ E R GL ++++ +LE+ + + E +L+A
Sbjct: 1662 DDALRSNEDLKEQ---LAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQ 1718
Query: 592 KLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVES 651
L +N L NT +AQ A V N+ + + + I +++ +
Sbjct: 1719 LLHSQN----TSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELK 1774
Query: 652 REDLIKNHY--MARIVELT--------------------SQLQLADSKSVHFYAECRALS 689
+E H M + +E T Q+Q +++ E
Sbjct: 1775 KEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQ 1834
Query: 690 KRLALA-------EKSKEALTEEMKLASQNISRLQ---DELTTTKRSYEDQLSMMSDHLC 739
KR A A E+ + +T + + +NI RLQ D+L +SY+ Q +
Sbjct: 1835 KRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEE--- 1891
Query: 740 SMNETLSK----QREEIDTLKMSSKGNSKKNKSR 769
N LS+ Q E + + + S+ NK R
Sbjct: 1892 QANTQLSRCRRVQHELEEAAERADIAESQVNKLR 1925
Score = 54.3 bits (129), Expect = 4e-07
Identities = 167/857 (19%), Positives = 328/857 (38%), Gaps = 130/857 (15%)
Query: 3 SAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSL 62
++EL K + L + S L K+ + D + ++++ + ++ L +EM +L
Sbjct: 937 NSELVAKKRNLEDKCSSL-------KRDIDDLELTLTKVEKEKHATENKVKNLSEEMTAL 989
Query: 63 TFRNLQLAKRVELLQD--ELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENE 120
+L K + LQ+ + L + + +++K +G EQ++ +DL+ +E+ +
Sbjct: 990 EENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQT---DDLEGSLEQEK 1046
Query: 121 RLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLE 180
+L + + + +E +L+ ++ Q + + L +K E + +LQ +
Sbjct: 1047 KLRA---DLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFE-LSQLQAKIDDEQ 1102
Query: 181 VKSQTLEKEAKECRLRTEECQLQLKTLH-----------------EDLSGRLEESLSIIN 223
V S +K+ KE + R EE + +++ H E++S RLEE+ +
Sbjct: 1103 VHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATS 1162
Query: 224 EKVPFNDTKYSQYNALNVPLHNR--RHQLKMRDIAGQALAFVQDLVTALLNFHTY----- 276
++ N + +++ + L +H+ + + V +L + N
Sbjct: 1163 AQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLE 1222
Query: 277 ---TEQRIQIFPVDSAIDTISPLN---QKFSQYLHENASYVRPLEEGMLHLFESITEDTV 330
+E +++I + S I+ +S ++ + + + S ++ +E L +
Sbjct: 1223 KEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKA 1282
Query: 331 TVLETTVKLKTFSEHLTSYICFLRK---ILPYQLKSLEEECESSLCTSALRARNLELSQ- 386
+ +L E S I L K L QL+ L+ + E A L+ S+
Sbjct: 1283 RLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRH 1342
Query: 387 DMKKMTAVFEKLQTYIALLALPSTEPDGLL---RTNYSSVLTNVGAALHGFHDVMKDISK 443
D + +E+ Q A L ++ + + RT Y + D ++ +
Sbjct: 1343 DCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYET-------------DAIQRTEE 1389
Query: 444 HYSQKAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPK 503
K + L A + T N S G++ +L+ + + K
Sbjct: 1390 LEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLM-RDLERSHTACATLDK 1448
Query: 504 AASGFISPLS------------AECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRIL 551
F L+ E + + + + +R E V E L RR
Sbjct: 1449 KQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETL--RREN 1506
Query: 552 LSSTESREGLAQQVQ------QSLEKISKL-EQEKEHWMLEAQLAKIKLEKENQRIADKL 604
+ E L +Q+ Q EK KL EQEK + + + LE E +I ++
Sbjct: 1507 KNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKIL-RV 1565
Query: 605 KNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVESREDLIK------- 657
+ S L ++ Q + ++ E +QS L ++ SR D ++
Sbjct: 1566 QLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSV-LDAEIRSRNDALRLKKKMEG 1624
Query: 658 ------------NHYMARIVE--LTSQLQLADSKSVHFYAECRA---LSKRLALAEKSKE 700
N MA + T Q QL DS+ +H R+ L ++LA+ E+
Sbjct: 1625 DLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQ-LHLDDALRSNEDLKEQLAIVERRNG 1683
Query: 701 AL---TEEMKLASQNISRLQDELTTTKRSYEDQLSMMSDH---LCSMNETL--SKQREEI 752
L EEMK+A + R T+R E +L SD L S N +L +K++ E
Sbjct: 1684 LLLEELEEMKVALEQTER-------TRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEA 1736
Query: 753 DTLKMSSKGNSKKNKSR 769
D + ++ + +SR
Sbjct: 1737 DIAQCQAEVENSIQESR 1753
Score = 43.5 bits (101), Expect = 7e-04
Identities = 78/394 (19%), Positives = 155/394 (39%), Gaps = 42/394 (10%)
Query: 6 LQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFR 65
LQG+ + L ++ + L K + A K++L L Q+E SL+
Sbjct: 1425 LQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTE 1484
Query: 66 NLQLAKRVELLQDELALSEPRGKK-NKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHI 124
++ E + D+L K ++ + + Q+++ K++ + + KK+ E E+ +
Sbjct: 1485 LFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDL 1544
Query: 125 QF----FEADEQHK-----HVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQ-- 173
Q E +H+ V+ EL + L+ + + ++ L R E LQ
Sbjct: 1545 QVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSV 1604
Query: 174 --------ND----KAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSI 221
ND K K+E +E + + E Q L+T + G+L++S
Sbjct: 1605 LDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRT----VQGQLKDSQLH 1660
Query: 222 INEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTE--Q 279
+++ + N+ Q + + RR+ L + ++ +A Q T L+ +
Sbjct: 1661 LDDALRSNEDLKEQ-----LAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASD 1715
Query: 280 RIQIFPVD--SAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTV 337
R+Q+ S I+T L +Q E + ++ ++IT D + E
Sbjct: 1716 RVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAIT-DAAMMAEELK 1774
Query: 338 KLKTFSEHLTSYICFLRKILPYQLKSLEEECESS 371
K + S HL ++K L +K L+ + +
Sbjct: 1775 KEQDTSAHLER----MKKNLEQTVKDLQHRLDEA 1804
Score = 35.8 bits (81), Expect = 0.15
Identities = 39/155 (25%), Positives = 68/155 (43%), Gaps = 27/155 (17%)
Query: 637 LEPIQSTSLVPDVESR-EDLIKNHYM--ARIVELTSQLQLADSKSVHFYAECRALSKR-- 691
L+ T + D E R E LIK+ + A++ ELT +L+ + + A+ R L +
Sbjct: 893 LQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCS 952
Query: 692 ------------LALAEKSKEA-------LTEEMKLASQNISRLQDELTTTKRSYE---D 729
L EK K A L+EEM +NIS+L E + + +++ D
Sbjct: 953 SLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLD 1012
Query: 730 QLSMMSDHLCSMNETLSKQREEIDTLKMSSKGNSK 764
L + D + + + +K ++ D L+ S + K
Sbjct: 1013 DLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKK 1047
Score = 31.6 bits (70), Expect = 2.9
Identities = 22/86 (25%), Positives = 37/86 (43%), Gaps = 4/86 (4%)
Query: 666 ELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKR 725
+L Q+Q + C L K L E + LTE ++ + + EL KR
Sbjct: 890 DLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEE----MNSELVAKKR 945
Query: 726 SYEDQLSMMSDHLCSMNETLSKQREE 751
+ ED+ S + + + TL+K +E
Sbjct: 946 NLEDKCSSLKRDIDDLELTLTKVEKE 971
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 62.0 bits (149), Expect = 2e-09
Identities = 86/416 (20%), Positives = 186/416 (44%), Gaps = 35/416 (8%)
Query: 2 ASAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDS 61
AS+E + + +KL Q+ Q + L+ E + ++++ +L+ ++ L LQ+ +
Sbjct: 736 ASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSE 795
Query: 62 LTFRNLQLAKRVELLQDELA-LSEPRGKKNKKSGESSSQLSQ--EQKSVFDEDLQKKIEE 118
++ L K +++L+++ A SE + E+ ++L Q EQ ++ DL+K E
Sbjct: 796 VSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLREN 855
Query: 119 NERLHIQFFEADEQHKHV-------EAELRSRLATLETEAAQHQAVVDGLTRKYMETIEK 171
+ +F E DE+ + + E ++ + ++Q + D L K + +E+
Sbjct: 856 LADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERD-VEE 914
Query: 172 LQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDT 231
LQ K + L+K ++ ++ E+ Q + HE+ LE LS + +K+ +T
Sbjct: 915 LQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKM---ET 971
Query: 232 KYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAID 291
++Q L R++ + + +Q+L LL+ TE +++ A +
Sbjct: 972 SHNQCQELKA-----RYERATSETKTKHEEILQNLQKTLLD----TEDKLK-----GARE 1017
Query: 292 TISPLNQKFSQYLHENASYVRPLE--EGMLHLFESITEDTVTVLETTVKLKTFSEHLTSY 349
S L Q+ + L + A + + E + + E +T++ L + K + L +
Sbjct: 1018 ENSGLLQELEE-LRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNE 1076
Query: 350 ICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKM-TAVFEKLQTYIAL 404
+ L++ LK++EE +S + + E ++++ + A +K Q AL
Sbjct: 1077 LDTLKE---NNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSAL 1129
Score = 60.8 bits (146), Expect = 4e-09
Identities = 164/809 (20%), Positives = 318/809 (39%), Gaps = 110/809 (13%)
Query: 36 ANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQDELALSEPRGKKN----- 90
+ + AL+E LK K Q + +L E D + V ++ ELAL+ ++
Sbjct: 348 SGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELE 407
Query: 91 --------------KKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEADEQHKHV 136
++ E +QL +E++ V EDLQ ++EE A K
Sbjct: 408 AKMDQLRTMVEAADREKVELLNQLEEEKRKV--EDLQFRVEEESITKGDLEVATVSEKSR 465
Query: 137 EAELRSRLATLETEAAQHQAVVD-----GLTRKYMETIEKLQNDKAKLEVKSQTLEKEAK 191
EL LA E A+ + ++ G + ++++ + + KLEV ++E
Sbjct: 466 IMELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREIT 525
Query: 192 ECR----LRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRR 247
+ R E Q ++K L+ E LS NE + ++ N+ + L +
Sbjct: 526 SLKEHFGAREETHQKEIKALYT-----ATEKLSKENESLKSKLEHANKENSDVIALWKSK 580
Query: 248 -------HQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAIDTISPLNQKF 300
HQ M ++ ++F + L T F Q I+ +D + + NQ+
Sbjct: 581 LETAIASHQQAMEELK---VSFSKGLGTETAEFAELKTQ-IEKMRLDYQHEIENLQNQQD 636
Query: 301 SQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKL-KTFSEHLTSYICFLRKILPY 359
S E A++ + +E L + I E ++ KL K +HL L K+
Sbjct: 637 S----ERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEA 692
Query: 360 QLKSLEEECESSLCTS-----------------------ALRARNLELSQDMKKMTAVFE 396
++K E E + C ALR + E +MKK+ E
Sbjct: 693 EIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLE 752
Query: 397 KLQTYIALLALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELP 456
+ I L + + SS+ + ++ +++S+ K +E EL
Sbjct: 753 AAEKQIKHLEIEKNAES----SKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQ 808
Query: 457 TATQKLITTNDCILSSVVALTNGAGKIA------SFFSNNLDYFIASLSYGPKAASGFIS 510
+K ++ +S ++ K+ + S++L+ +L+ A
Sbjct: 809 ILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLA--DMEAKFREK 866
Query: 511 PLSAECMLQYKKKAAAYMKSLRK------PLLESVPYEEALANR---RILLSSTESREGL 561
E +++ K+K + + K L + E L R + L T++ E
Sbjct: 867 DEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANEN- 925
Query: 562 AQQVQQSLEKIS-KLEQEKEHWMLEAQLAKIKLEKENQRIADKLKNTGSAQLVGLAQENA 620
A +Q+S+E ++ K EQ ++ + + K +LE++ + K++ + + A+
Sbjct: 926 ASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYER 985
Query: 621 AVSNTAGQDEATAKAVLEPIQSTSLVPDVESREDLIKNHYMARIVELTSQLQLAD-SKSV 679
A S T + E +L+ +Q T L D E + + + EL + AD +K+
Sbjct: 986 ATSETKTKHEE----ILQNLQKTLL--DTEDKLKGAREENSGLLQELEELRKQADKAKAA 1039
Query: 680 HFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSY---EDQLSMMSD 736
+ + +++ + A E+ K Q ++LQ+EL T K + ++L+ +
Sbjct: 1040 QTAEDAMQIMEQMTKEKTETLASLEDTK---QTNAKLQNELDTLKENNLKNVEELNKSKE 1096
Query: 737 HLCSMNETLSKQREEIDTLKMSSKGNSKK 765
L N+ + + R+EI+TLK ++ S++
Sbjct: 1097 LLTVENQKMEEFRKEIETLKQAAAQKSQQ 1125
Score = 55.1 bits (131), Expect = 2e-07
Identities = 56/241 (23%), Positives = 115/241 (47%), Gaps = 13/241 (5%)
Query: 15 QEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVE 74
Q +KL+ + LK+ + KE L +++Q + + ++E+++L Q ++++
Sbjct: 1068 QTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLS 1127
Query: 75 LLQDE-LALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEADEQH 133
LQ+E + L+E G+ + +S Q +E++SV + L +E +R +ADE+
Sbjct: 1128 ALQEENVKLAEELGRSRDEV--TSHQKLEEERSVLNNQL---LEMKKRESKFIKDADEE- 1181
Query: 134 KHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAK-LEVKSQTLEKEAKE 192
+A L+ ++ + A ++ L + T+ + +N AK L QTLE + +
Sbjct: 1182 ---KASLQKSISITSALLTEKDAELEKLRNEV--TVLRGENASAKSLHSVVQTLESDKVK 1236
Query: 193 CRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKM 252
L+ + +LQLK LS + + +E +++ N++ V L + LKM
Sbjct: 1237 LELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQESQIDFLNSVIVDLQRKNQDLKM 1296
Query: 253 R 253
+
Sbjct: 1297 K 1297
Score = 41.2 bits (95), Expect = 0.004
Identities = 124/697 (17%), Positives = 258/697 (37%), Gaps = 118/697 (16%)
Query: 91 KKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEADEQHKHVEAELR-------SR 143
K SG ++ Q + ++K + +++ + E + + +A +E EL
Sbjct: 346 KISGTTALQEALKEKQ---QHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQH 402
Query: 144 LATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEA---KECRLRTEEC 200
+ LE + Q + +V+ R+ +E + +L+ +K K+E +E+E+ + + T
Sbjct: 403 VLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSE 462
Query: 201 QLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQAL 260
+ ++ L +DL+ R++E + R +L+ AG
Sbjct: 463 KSRIMELEKDLALRVQEVAEL-------------------------RRRLESNKPAGDV- 496
Query: 261 AFVQDLVTALLNFHTYTEQRIQIFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLH 320
D+ +LL IS L +K ++ + L+E
Sbjct: 497 ----DMSLSLL-------------------QEISSLQEKLEVTRTDHQREITSLKEHFGA 533
Query: 321 LFESITEDTVTVLETTVKLKTFSEHLTSYICFLRKILPYQLKSLEEECESSLCT--SALR 378
E+ ++ + T KL +E L S + K + + + E+++ + A+
Sbjct: 534 REETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAME 593
Query: 379 ARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNVGAALHGFH-DV 437
+ S+ + TA F +L+T I + L L+ S + +
Sbjct: 594 ELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKL 653
Query: 438 MKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNNLDYFIAS 497
MK I + + AI +L A + + + L+ + + A L+ A
Sbjct: 654 MKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKL--------QEAEIKVKELEVLQAK 705
Query: 498 LSYGPKAASGFISPLSAE----CMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLS 553
+ K F S L A L +KA++ KS K L + + E +
Sbjct: 706 CNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEK 765
Query: 554 STESRE--GLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRIADKLKNTGSAQ 611
+ ES + + +++Q K++ L++ + E K LEKE Q + +K
Sbjct: 766 NAESSKASSITRELQGRELKLTNLQEN----LSEVSQVKETLEKELQILKEKFAEA---- 817
Query: 612 LVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVESREDLIKNHYMARIVELTSQL 671
AVS E K + Q L D+E + + ++ ++
Sbjct: 818 ------SEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRE--------NLADMEAKF 863
Query: 672 QLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQN---ISRLQDELTTTKRSYE 728
+ D + + + EK + + E MK++ N ++++ DEL +R E
Sbjct: 864 REKDERE----------EQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVE 913
Query: 729 DQLSMMSDHLCSMNETLSKQREEIDTLKMSSKGNSKK 765
+ + L NE S ++ I+ + + ++ + ++
Sbjct: 914 E----LQLKLTKANENASFLQKSIEDMTVKAEQSQQE 946
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 62.0 bits (149), Expect = 2e-09
Identities = 86/416 (20%), Positives = 186/416 (44%), Gaps = 35/416 (8%)
Query: 2 ASAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDS 61
AS+E + + +KL Q+ Q + L+ E + ++++ +L+ ++ L LQ+ +
Sbjct: 771 ASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSE 830
Query: 62 LTFRNLQLAKRVELLQDELA-LSEPRGKKNKKSGESSSQLSQ--EQKSVFDEDLQKKIEE 118
++ L K +++L+++ A SE + E+ ++L Q EQ ++ DL+K E
Sbjct: 831 VSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLREN 890
Query: 119 NERLHIQFFEADEQHKHV-------EAELRSRLATLETEAAQHQAVVDGLTRKYMETIEK 171
+ +F E DE+ + + E ++ + ++Q + D L K + +E+
Sbjct: 891 LADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERD-VEE 949
Query: 172 LQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDT 231
LQ K + L+K ++ ++ E+ Q + HE+ LE LS + +K+ +T
Sbjct: 950 LQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKM---ET 1006
Query: 232 KYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAID 291
++Q L R++ + + +Q+L LL+ TE +++ A +
Sbjct: 1007 SHNQCQELKA-----RYERATSETKTKHEEILQNLQKTLLD----TEDKLK-----GARE 1052
Query: 292 TISPLNQKFSQYLHENASYVRPLE--EGMLHLFESITEDTVTVLETTVKLKTFSEHLTSY 349
S L Q+ + L + A + + E + + E +T++ L + K + L +
Sbjct: 1053 ENSGLLQELEE-LRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNE 1111
Query: 350 ICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKM-TAVFEKLQTYIAL 404
+ L++ LK++EE +S + + E ++++ + A +K Q AL
Sbjct: 1112 LDTLKE---NNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSAL 1164
Score = 60.1 bits (144), Expect = 8e-09
Identities = 150/813 (18%), Positives = 327/813 (40%), Gaps = 92/813 (11%)
Query: 11 QKLAQEYSKLRAQNQVLKKGVVD-----EQANSAALKEQLKMKDQSLRKLQQEMDSLTFR 65
+K E + R + + + KG ++ E A L++ L + KLQ+E++
Sbjct: 434 EKRKVEDLQFRVEEESITKGDLETQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVA 493
Query: 66 NLQLAKRVELLQDELALS-------EPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEE 118
+ R+ L+ +LAL R + NK +G+ LS Q+ LQ+K+E
Sbjct: 494 TVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEI---SSLQEKLEV 550
Query: 119 NERLHIQFFEADEQH-----KHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQ 173
H + + ++H + + E+++ E + +++++ L E + +
Sbjct: 551 TRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIA 610
Query: 174 NDKAKLEVKSQTLEKEAKECR------LRTEECQL-QLKTLHEDLSGRLEESLSIINEKV 226
K+KLE + ++ +E + L TE + +LKT E + RL+ I N +
Sbjct: 611 LWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKM--RLDYQHEIENLQN 668
Query: 227 PFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQAL------AFVQDLVTALLNFHTYTEQR 280
+ + + + +K ++ + +A+ A Q LV + E
Sbjct: 669 QQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAE 728
Query: 281 IQIFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLK 340
I++ ++ + + ++ + S ++ EE +L L +++ + + KL+
Sbjct: 729 IKV----KELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDL-DALRKASSEGKSEMKKLR 783
Query: 341 TFSEHLTSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELS---QDMKKMTAVFEK 397
E I L +++ E ++S T L+ R L+L+ +++ +++ V E
Sbjct: 784 QQLEAAEKQIKHL------EIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKET 837
Query: 398 LQTYIALL----ALPSTEPDGLLRTNYSSV---------LTNVGAALHGFHDVMKDISKH 444
L+ + +L A S E + R+ +V + + L + + D+
Sbjct: 838 LEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAK 897
Query: 445 YSQKAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNNL---DYFIASLSYG 501
+ +K E +L A +KL ND ++ ++ ++ + ++ L + + L
Sbjct: 898 FREKDEREEQLIKAKEKL--END--IAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLK 953
Query: 502 PKAASGFISPLSAECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLSSTESREGL 561
A+ S L K + ++ +K E E L++ L E+
Sbjct: 954 LTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSD---LEKKMETSHNQ 1010
Query: 562 AQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKEN-------------QRIADKLKNTG 608
Q+++ E+ + E + +H + L K L+ E+ Q + + K
Sbjct: 1011 CQELKARYERATS-ETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAD 1069
Query: 609 SAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVESREDLIKNHYMARIVELT 668
A+ A++ + +++ A LE + T+ +++ D +K + + + EL
Sbjct: 1070 KAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTN--AKLQNELDTLKENNLKNVEELN 1127
Query: 669 SQ---LQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKR 725
L + + K F E L + A + AL EE ++ + R +DE+T+ ++
Sbjct: 1128 KSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQK 1187
Query: 726 SYEDQLSMMSDHLCSMNETLSKQREEIDTLKMS 758
E++ S++++ L M + SK ++ D K S
Sbjct: 1188 -LEEERSVLNNQLLEMKKRESKFIKDADEEKAS 1219
Score = 55.1 bits (131), Expect = 2e-07
Identities = 167/844 (19%), Positives = 327/844 (38%), Gaps = 145/844 (17%)
Query: 36 ANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQDELALSEPRGKKN----- 90
+ + AL+E LK K Q + +L E D + V ++ ELAL+ ++
Sbjct: 348 SGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELE 407
Query: 91 --------------KKSGESSSQLSQEQKSVFDEDLQKKIEEN----------------- 119
++ E +QL +E++ V EDLQ ++EE
Sbjct: 408 AKMDQLRTMVEAADREKVELLNQLEEEKRKV--EDLQFRVEEESITKGDLETQTKLEHAR 465
Query: 120 -----ERLHIQFFEADEQHKHVE------AELRSRLATLETEAAQHQAVVDGLTRKY--- 165
+ L + +AD+ + +E +SR+ LE + A V L R+
Sbjct: 466 IKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESN 525
Query: 166 ---------METIEKLQNDKAKLEVKSQTLEKEAKECR----LRTEECQLQLKTLHEDLS 212
+ ++++ + + KLEV ++E + R E Q ++K L+
Sbjct: 526 KPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYT--- 582
Query: 213 GRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRR-------HQLKMRDIAGQALAFVQD 265
E LS NE + ++ N+ + L + HQ M ++ ++F +
Sbjct: 583 --ATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELK---VSFSKG 637
Query: 266 LVTALLNFHTYTEQRIQIFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESI 325
L T F Q I+ +D + + NQ+ S E A++ + +E L + I
Sbjct: 638 LGTETAEFAELKTQ-IEKMRLDYQHEIENLQNQQDS----ERAAHAKEMEALRAKLMKVI 692
Query: 326 TEDTVTVLETTVKL-KTFSEHLTSYICFLRKILPYQLKSLEEECESSLCTS--------- 375
E ++ KL K +HL L K+ ++K E E + C
Sbjct: 693 KEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFT 752
Query: 376 --------------ALRARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNYS 421
ALR + E +MKK+ E + I L + + S
Sbjct: 753 SQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAES----SKAS 808
Query: 422 SVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNGAG 481
S+ + ++ +++S+ K +E EL +K ++ +S ++
Sbjct: 809 SITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVN 868
Query: 482 KIA------SFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAAYMKSLRK-- 533
K+ + S++L+ +L+ A E +++ K+K + + K
Sbjct: 869 KLHQKEEQFNMLSSDLEKLRENLA--DMEAKFREKDEREEQLIKAKEKLENDIAEIMKMS 926
Query: 534 ----PLLESVPYEEALANR---RILLSSTESREGLAQQVQQSLEKIS-KLEQEKEHWMLE 585
L + E L R + L T++ E A +Q+S+E ++ K EQ ++ +
Sbjct: 927 GDNSSQLTKMNDELRLKERDVEELQLKLTKANEN-ASFLQKSIEDMTVKAEQSQQEAAKK 985
Query: 586 AQLAKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSL 645
+ K +LE++ + K++ + + A+ A S T + E +L+ +Q T L
Sbjct: 986 HEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEE----ILQNLQKTLL 1041
Query: 646 VPDVESREDLIKNHYMARIVELTSQLQLAD-SKSVHFYAECRALSKRLALAEKSKEALTE 704
D E + + + EL + AD +K+ + + +++ + A E
Sbjct: 1042 --DTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLE 1099
Query: 705 EMKLASQNISRLQDELTTTKRSY---EDQLSMMSDHLCSMNETLSKQREEIDTLKMSSKG 761
+ K Q ++LQ+EL T K + ++L+ + L N+ + + R+EI+TLK ++
Sbjct: 1100 DTK---QTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQ 1156
Query: 762 NSKK 765
S++
Sbjct: 1157 KSQQ 1160
Score = 55.1 bits (131), Expect = 2e-07
Identities = 56/241 (23%), Positives = 115/241 (47%), Gaps = 13/241 (5%)
Query: 15 QEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVE 74
Q +KL+ + LK+ + KE L +++Q + + ++E+++L Q ++++
Sbjct: 1103 QTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLS 1162
Query: 75 LLQDE-LALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEADEQH 133
LQ+E + L+E G+ + +S Q +E++SV + L +E +R +ADE+
Sbjct: 1163 ALQEENVKLAEELGRSRDEV--TSHQKLEEERSVLNNQL---LEMKKRESKFIKDADEE- 1216
Query: 134 KHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAK-LEVKSQTLEKEAKE 192
+A L+ ++ + A ++ L + T+ + +N AK L QTLE + +
Sbjct: 1217 ---KASLQKSISITSALLTEKDAELEKLRNEV--TVLRGENASAKSLHSVVQTLESDKVK 1271
Query: 193 CRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKM 252
L+ + +LQLK LS + + +E +++ N++ V L + LKM
Sbjct: 1272 LELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQESQIDFLNSVIVDLQRKNQDLKM 1331
Query: 253 R 253
+
Sbjct: 1332 K 1332
Score = 48.1 bits (113), Expect = 3e-05
Identities = 129/697 (18%), Positives = 263/697 (37%), Gaps = 83/697 (11%)
Query: 91 KKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEADEQHKHVEAELR-------SR 143
K SG ++ Q + ++K + +++ + E + + +A +E EL
Sbjct: 346 KISGTTALQEALKEKQ---QHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQH 402
Query: 144 LATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQ 203
+ LE + Q + +V+ R+ +E + +L+ +K K+E +E+E+ + + + Q
Sbjct: 403 VLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEES----ITKGDLETQ 458
Query: 204 LKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFV 263
K H + LE+SL K + V +R +L+ +D+A +
Sbjct: 459 TKLEHARIK-ELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELE-KDLALR----- 511
Query: 264 QDLVTALLNFHTYTEQRIQIFPVD---SAIDTISPLNQKFSQYLHENASYVRPLEEGMLH 320
V + E VD S + IS L +K ++ + L+E
Sbjct: 512 ---VQEVAELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGA 568
Query: 321 LFESITEDTVTVLETTVKLKTFSEHLTSYICFLRKILPYQLKSLEEECESSLCT--SALR 378
E+ ++ + T KL +E L S + K + + + E+++ + A+
Sbjct: 569 REETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAME 628
Query: 379 ARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNVGAALHGFH-DV 437
+ S+ + TA F +L+T I + L L+ S + +
Sbjct: 629 ELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKL 688
Query: 438 MKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNNLDYFIAS 497
MK I + + AI +L A + + + L+ + + A L+ A
Sbjct: 689 MKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKL--------QEAEIKVKELEVLQAK 740
Query: 498 LSYGPKAASGFISPLSAE----CMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLS 553
+ K F S L A L +KA++ KS K L + + E +
Sbjct: 741 CNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEK 800
Query: 554 STESRE--GLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRIADKLKNTGSAQ 611
+ ES + + +++Q K++ L++ + E K LEKE Q + +K
Sbjct: 801 NAESSKASSITRELQGRELKLTNLQEN----LSEVSQVKETLEKELQILKEKFAEA---- 852
Query: 612 LVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVESREDLIKNHYMARIVELTSQL 671
AVS E K + Q L D+E + + ++ ++
Sbjct: 853 ------SEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRE--------NLADMEAKF 898
Query: 672 QLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQN---ISRLQDELTTTKRSYE 728
+ D + + + EK + + E MK++ N ++++ DEL +R E
Sbjct: 899 REKDERE----------EQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVE 948
Query: 729 DQLSMMSDHLCSMNETLSKQREEIDTLKMSSKGNSKK 765
+ + L NE S ++ I+ + + ++ + ++
Sbjct: 949 E----LQLKLTKANENASFLQKSIEDMTVKAEQSQQE 981
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 61.2 bits (147), Expect = 3e-09
Identities = 156/858 (18%), Positives = 305/858 (35%), Gaps = 115/858 (13%)
Query: 11 QKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLA 70
Q+L + KL + L + + QA A LK QL K++ L+ ++ +
Sbjct: 1044 QELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMAL 1103
Query: 71 KRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEAD 130
K++ L+ +++ + ++ +S +S +++QK E+L+ E E
Sbjct: 1104 KKIRELESQISELQ----EDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ 1159
Query: 131 EQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQND-------KAKLEVKS 183
E E E+ TLE EA H+A + + +K+ + +E+L KA LE
Sbjct: 1160 ELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAK 1219
Query: 184 QTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTK------YSQYN 237
QTLE E E E ++ L+ + R + + +V FN+ + +
Sbjct: 1220 QTLENERGEL---ANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVT 1276
Query: 238 ALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALL--NFHTYTEQRIQIFPVDSAIDTISP 295
L V L N L D L + + L E+ Q + + + +
Sbjct: 1277 KLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVED 1336
Query: 296 LNQKFSQYLHENASYVRPLEEGMLHLFESIT------EDTVTVLETTVKLKT-------- 341
F + L E LE+ + L + ED+V LET ++K
Sbjct: 1337 EKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEG 1396
Query: 342 FSEHLTSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTY 401
S+ + K+ + + +E + + R L + KK + + +T
Sbjct: 1397 LSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTI 1456
Query: 402 IALLALPSTEPDGLLRTNYSSVL------------------------TNVGAALHGFHDV 437
A A + R + L T + + DV
Sbjct: 1457 SAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDV 1516
Query: 438 MKDISKHYSQKAAIE---HELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNNLDYF 494
K + + K A+E E+ T ++L + + L + + F +L
Sbjct: 1517 GKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGR 1576
Query: 495 IASLSYGPKAASGFISPLSAECMLQYKKK--AAAYMKSLRKPLLESVPY--------EEA 544
K + + AE + K++ A A K L L + + +EA
Sbjct: 1577 DEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEA 1636
Query: 545 LANRRILLSSTESREGLAQQVQQSLEKI--SKLEQEKEHWMLEAQL------------AK 590
+ R L + + + S E+I E EK+ +EA++ AK
Sbjct: 1637 IKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAK 1696
Query: 591 IKLEKENQRIADKLKNTGSAQLVGLAQEN------AAVSNTAGQDEATAKAVLEPIQSTS 644
+ ++E +AD++ N+ + L ++ A + +++ + + + ++ +
Sbjct: 1697 RQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKAN 1756
Query: 645 L-VPDVESREDLIKNHYM----------ARIVELTSQLQ-LADSKSVHFYAECRALSKRL 692
L + + + +L ++H + EL +LQ + + + A AL ++
Sbjct: 1757 LQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKI 1816
Query: 693 ALAEKSKEALTEEMKLASQNISRLQ----------DELTTTKRSYEDQLSMMSDHLCSMN 742
A E+ + T+E + A + + R + D+ Y+DQ S L +
Sbjct: 1817 AQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLK 1876
Query: 743 ETLSKQREEIDTLKMSSK 760
L + EE S +
Sbjct: 1877 RQLEEAEEEAQRANASRR 1894
Score = 60.5 bits (145), Expect = 6e-09
Identities = 156/812 (19%), Positives = 330/812 (40%), Gaps = 112/812 (13%)
Query: 5 ELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTF 64
E + + Q L E K++ Q L++ + +E++ L+ + + L+KL++E L
Sbjct: 926 EEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILED 985
Query: 65 RNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHI 124
+N +LAK +LL+D +A + ++ +S ++L + +++ DL++++ E+
Sbjct: 986 QNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMI-TDLEERLRREEK--- 1041
Query: 125 QFFEADEQHKHVE----------AELRSRLATLETEAAQHQAVVD-GLTRKYMETIEKLQ 173
Q E ++ + +E AEL++++A L+ + A+ + + L R E +K
Sbjct: 1042 QRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNM 1101
Query: 174 NDKAKLEVKSQ--TLEKEAKECRLRTEECQLQLKTLHEDLSG---RLEESLSIINEKVPF 228
K E++SQ L+++ + R + + Q + L E+L LE++L +
Sbjct: 1102 ALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQEL 1161
Query: 229 NDTKYSQYNALNVPLHN--RRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPV 286
+ + N L L + H+ +++++ + V++L L EQ ++
Sbjct: 1162 RSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQL-------EQTKRVKA- 1213
Query: 287 DSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHL 346
+ Q E A+ V+ L +G + + E VK
Sbjct: 1214 -----NLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGER-- 1266
Query: 347 TSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLA 406
+R L ++ L+ E ++ T L + + S+ K +A+ +LQ LL
Sbjct: 1267 ------VRTELADKVTKLQVELDN--VTGLLSQSDSKSSKLTKDFSALESQLQDTQELL- 1317
Query: 407 LPSTEPDGLLRTNYSSVLTNVGAALHGF-----------HDVMKDISKHYSQKAAIEHEL 455
+ + + + S+ L V + F H++ K I+ ++Q A ++ ++
Sbjct: 1318 ----QEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKM 1373
Query: 456 PTATQKLITTNDCIL-------------SSVVALTNGAGKIASFFSNNLDYFIASLSYGP 502
+ L T + VA + K + LD + L +
Sbjct: 1374 EDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQR 1433
Query: 503 KAASGFISPLSA--ECMLQYKKKAAAYMKSLRKPLLESVPYE-EALANRRILLSSTESR- 558
++A + + + K +A Y + + E+ E +AL+ R L + E +
Sbjct: 1434 QSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKA 1493
Query: 559 --EGLAQQVQQSLEKI---------SKLEQEKEHWMLEAQLAKIKLEKENQRIADKLKNT 607
E L +Q + +E + S E EK LE Q+ ++K + E + D+L+ T
Sbjct: 1494 ELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLE--ELEDELQAT 1551
Query: 608 GSAQL---VGLAQENAAVS-NTAGQDEATAKAVLEPIQSTSLVPDVESREDLIKNHYMAR 663
A+L V L A + G+DE + + + LV V E +++ R
Sbjct: 1552 EDAKLRLEVNLQAMKAQFERDLQGRDEQSEE------KKKQLVRQVREMEAELEDERKQR 1605
Query: 664 IVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDELTTT 723
+ + ++ +L + + L + A K+++ ++++ + EL T
Sbjct: 1606 SMAVAARKKLE--------MDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDT 1657
Query: 724 KRSYEDQLSMMSDH---LCSMNETLSKQREEI 752
+ S E+ L+ ++ L SM + + +EE+
Sbjct: 1658 RASREEILAQAKENEKKLKSMEAEMIQLQEEL 1689
Score = 50.4 bits (119), Expect = 6e-06
Identities = 146/824 (17%), Positives = 312/824 (37%), Gaps = 103/824 (12%)
Query: 4 AELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDS-- 61
AELQ + +L + +K + Q V +E A ++++ + + +LQ++++S
Sbjct: 1065 AELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESER 1124
Query: 62 -----LTFRNLQLAKRVELLQDEL--------ALSEPRGKKNKKSGESSSQLSQEQKSVF 108
+ L + +E L+ EL A E R K+ ++ L +E K+
Sbjct: 1125 ASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKT-H 1183
Query: 109 DEDLQKKIEENERLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMET 168
+ +Q+ +++ + + E EQ K V+A L TLE E + V L + ++
Sbjct: 1184 EAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDS 1243
Query: 169 IEKLQNDKAKLE---VKSQTLEKEAKECRLRTEECQLQLKTL------HEDLSGRLEESL 219
K + +A+L+ VK E+ E + + Q++L + + S +L +
Sbjct: 1244 EHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDF 1303
Query: 220 SIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQ 279
S + ++ + N + L K++ + + +F + L H +Q
Sbjct: 1304 SALESQLQDTQELLQEENRQKLSLST-----KLKQVEDEKNSFREQLEEEEEAKHNLEKQ 1358
Query: 280 ----RIQIFPVDSAI-DTISPLN--QKFSQYLHENASYVRPLEEGMLHLFESITEDTVTV 332
Q+ + + D++ L ++ + L ++ + E + ++ + + +
Sbjct: 1359 IATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRL 1418
Query: 333 LETTVKLKTFSEHLTSYICFLRKILPY--QLKSLEEECESSLCTSALRARNLELSQDMKK 390
+ L +H C L K QL + E+ + RA ++ K
Sbjct: 1419 QQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKA 1478
Query: 391 MT---AVFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQ 447
++ A+ E ++ L L RT ++++ H++ K Q
Sbjct: 1479 LSLARALEEAMEQKAELERLNKQ-----FRTEMEDLMSSKDDVGKSVHELEKSKRALEQQ 1533
Query: 448 KAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKAASG 507
++ +L +L T D L V L + + F +L K
Sbjct: 1534 VEEMKTQLEELEDELQATEDAKLRLEVNLQ----AMKAQFERDLQGRDEQSEEKKKQLVR 1589
Query: 508 FISPLSAECMLQYKKK--AAAYMKSLRKPLLESVPY--------EEALANRRILLSSTE- 556
+ + AE + K++ A A K L L + + +EA+ R L + +
Sbjct: 1590 QVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKD 1649
Query: 557 ----------SREGLAQQVQQSLEKISKLEQEK---EHWMLEAQLAKIKLEKENQRIADK 603
SRE + Q +++ +K+ +E E + + A+ AK + ++E +AD+
Sbjct: 1650 CMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADE 1709
Query: 604 LKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVESREDLIKNHYMAR 663
+ N+ + L ++ + A +E E +T L+ D + +L +
Sbjct: 1710 IANSSGKGALALEEKRRLEARIAQLEEELE----EEQGNTELINDRLKKANL-------Q 1758
Query: 664 IVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDELTTT 723
I ++ + L L R+ +++ A + E +E+K+ +LQ+ T
Sbjct: 1759 IDQINTDLNLE-----------RSHAQKNENARQQLERQNKELKV------KLQEMEGTV 1801
Query: 724 KRSYEDQLSMMSDHLCSMNETLSKQREEIDTLKMSSKGNSKKNK 767
K Y+ ++ + + + E L + +E + KK K
Sbjct: 1802 KSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLK 1845
Score = 48.5 bits (114), Expect = 2e-05
Identities = 55/282 (19%), Positives = 121/282 (42%), Gaps = 37/282 (13%)
Query: 5 ELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTF 64
+LQG+ ++ ++ +L Q + ++ + DE+ + K + L+ L+ +DS
Sbjct: 1572 DLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANK 1631
Query: 65 RNLQLAKRVELLQ-----------------DELALSEPRGKKNKKSGESSSQLSQEQKSV 107
+ K++ LQ +E+ +K KS E+ QE+ +
Sbjct: 1632 NRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAA 1691
Query: 108 FDEDLQKKIEENERLHIQFFEAD-------EQHKHVEAELRSRLATLETEAAQHQAVVDG 160
+ ++ +E + L + + E+ + +EA + LE E + + D
Sbjct: 1692 AERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDR 1751
Query: 161 LTRKYMETIEKLQND-------KAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSG 213
L + ++ I+++ D K E Q LE++ KE +++ +E + +K+ ++
Sbjct: 1752 LKKANLQ-IDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASIT 1810
Query: 214 RLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDI 255
LE ++ + E++ N+TK Q V RR + K++D+
Sbjct: 1811 ALEAKIAQLEEQLD-NETKERQAACKQV----RRTEKKLKDV 1847
Score = 41.6 bits (96), Expect = 0.003
Identities = 55/244 (22%), Positives = 99/244 (40%), Gaps = 23/244 (9%)
Query: 512 LSAECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLSSTESREGLAQQVQQSLEK 571
L + LQ + + A + LR L E + + L + E E Q +Q +K
Sbjct: 883 LQLQEQLQAETELCAEAEELRARLTAKKQELEEICHD--LEARVEEEEERCQHLQAEKKK 940
Query: 572 ISKLEQEKEHWMLEAQLAKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEA 631
+ + QE E + E + A+ KL+ E KLK Q++ L +N + A
Sbjct: 941 MQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQII-LEDQNCKL--------A 991
Query: 632 TAKAVLE---PIQSTSLVPDVESREDL--IKNHYMARIVELTSQLQLADSKSVHFYAECR 686
K +LE +T+L + E + L +KN + A I +L +L+ + + +
Sbjct: 992 KEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQR-------Q 1044
Query: 687 ALSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLS 746
L K E L++++ I+ L+ +L + + L+ + + N L
Sbjct: 1045 ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALK 1104
Query: 747 KQRE 750
K RE
Sbjct: 1105 KIRE 1108
Score = 40.8 bits (94), Expect = 0.005
Identities = 51/238 (21%), Positives = 102/238 (42%), Gaps = 36/238 (15%)
Query: 528 MKSLRKPLL-ESVPYEEALANRRILLSSTESREGLAQQVQQSLEKI-----SKLEQEKEH 581
M++L+ L+ E + +E L L + E +Q LE+I +++E+E+E
Sbjct: 871 METLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEER 930
Query: 582 WMLEAQLAKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQ 641
Q K K+++ Q + ++L+ SA+ ++ V+ A + + ++ Q
Sbjct: 931 CQ-HLQAEKKKMQQNIQELEEQLEEEESARQKLQLEK---VTTEAKLKKLEEEQIILEDQ 986
Query: 642 STSLVPDVESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEA 701
+ L + + ED RI E T+ L + KS K LA + EA
Sbjct: 987 NCKLAKEKKLLED--------RIAEFTTNLTEEEEKS-----------KSLAKLKNKHEA 1027
Query: 702 LTEEMKLASQNISRLQDELTTTKRSYE-------DQLSMMSDHLCSMNETLSKQREEI 752
+ +++ + + + EL T+R E DQ++ + + + L+K+ EE+
Sbjct: 1028 MITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEEL 1085
Score = 36.6 bits (83), Expect = 0.090
Identities = 43/225 (19%), Positives = 94/225 (41%), Gaps = 19/225 (8%)
Query: 4 AELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMD--- 60
A GK +E +L A+ L++ + +EQ N+ + ++LK + + ++ +++
Sbjct: 1711 ANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLER 1770
Query: 61 SLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQK-SVFDEDLQKKIEEN 119
S +N +++E EL + + KS +S + E K + +E L + +E
Sbjct: 1771 SHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKER 1830
Query: 120 ERLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKL 179
+ A +Q + E +L+ L ++ E +Y + +K +L
Sbjct: 1831 Q-------AACKQVRRTEKKLKDVLLQVDDERRN--------AEQYKDQADKASTRLKQL 1875
Query: 180 EVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINE 224
+ + + E+EA+ + Q +L+ E E S+ N+
Sbjct: 1876 KRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNK 1920
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 61.2 bits (147), Expect = 3e-09
Identities = 159/798 (19%), Positives = 311/798 (38%), Gaps = 87/798 (10%)
Query: 11 QKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLA 70
Q+L + KL + L+ + + QA LK QL K++ L+ D T
Sbjct: 1051 QELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNAL 1110
Query: 71 KRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQK-KIEENERLHIQFFEA 129
K V LQ ++A + ++ +S ++S +++QK E+L+ K E + L +
Sbjct: 1111 KVVRELQAQIAELQ----EDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQ 1166
Query: 130 DEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQND-------KAKLEVK 182
+ + K E E+ LE E H+A + + +++ +E+L KA LE
Sbjct: 1167 ELRTKR-EQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKN 1225
Query: 183 SQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALNVP 242
Q LE + KE + Q Q+K E +L+ + ++ KV D +
Sbjct: 1226 KQGLETDNKELACEVKVLQ-QVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASK 1284
Query: 243 LHNRRHQLK--MRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAIDTISPLNQKF 300
L N + + + + + F +D + E ++Q DT L ++
Sbjct: 1285 LQNELDNVSTLLEEAEKKGIKFAKDAAS--------LESQLQ--------DTQELLQEET 1328
Query: 301 SQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSYICFLRKILPYQ 360
Q L+ +S +R LEE L E E+ E L+ L S + +K +
Sbjct: 1329 RQKLN-LSSRIRQLEEEKNSLQEQQEEEE----EARKNLEKQVLALQSQLADTKKKVDDD 1383
Query: 361 LKSLE--EECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLL-- 416
L ++E EE + L A LSQ +++ ++KL+ L E D L
Sbjct: 1384 LGTIESLEEAKKKLLKDA-----EALSQRLEEKALAYDKLEKTKNRL---QQELDDLTVD 1435
Query: 417 RTNYSSVLTNVGAALHGFHDVM---KDISKHYS-QKAAIEHELPTATQKLITTNDCILSS 472
+ V +N+ F ++ K IS Y+ ++ E E K ++ + +
Sbjct: 1436 LDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEA 1495
Query: 473 VVALTNGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAAYMKSLR 532
+ A + ++ D + G L+ K+A
Sbjct: 1496 LEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHE-----------LEKSKRALEQQVEEM 1544
Query: 533 KPLLESVPYEEALANRRILLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIK 592
+ LE + +E A L + + + Q ++ L+ + +EK+ +++ Q+ +++
Sbjct: 1545 RTQLEELE-DELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIK-QVRELE 1602
Query: 593 LEKENQR------IADKLK-----NTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQ 641
E E++R +A K K AQ+ + V + +A K ++
Sbjct: 1603 AELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELE 1662
Query: 642 STSLVPD---VESREDLIK-NHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEK 697
D +S+E K A I++L +L ++ H E L+ + +
Sbjct: 1663 EARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSAS 1722
Query: 698 SKEALTEEMKLASQNISRLQDELTTTKRSYE---DQLSMMSDHLCSMNETLSKQR---EE 751
K AL +E + I++L++EL + + E D+ + + ++N L+ +R ++
Sbjct: 1723 GKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQK 1782
Query: 752 IDTLKMSSKGNSKKNKSR 769
D + + +K+ K++
Sbjct: 1783 SDNARQQLERQNKELKAK 1800
Score = 58.2 bits (139), Expect = 3e-08
Identities = 158/775 (20%), Positives = 306/775 (39%), Gaps = 90/775 (11%)
Query: 5 ELQGKYQKLAQEYSKLRAQNQV---LKKGVVDEQANSAALKEQLK--MKDQSLRKLQQEM 59
E++ K+Q+L +E + L Q Q L + +A AA K++L+ + D R ++E
Sbjct: 877 EMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEE 936
Query: 60 DSLTFRNLQLAKRVELLQDELALSEPRGKKNKK-----SGESSSQLSQEQKSVFDEDLQK 114
+ +N + + + E L E G + K + E+ + +E+ + ++ K
Sbjct: 937 RNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSK 996
Query: 115 KIEENERLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQN 174
I+E + + + E Q E E LA + + + ++ +K +T ++L+
Sbjct: 997 FIKEKKLMEDRIAECSSQLAE-EEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEK 1055
Query: 175 DKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYS 234
K KL+ ++ L+ + E + + +E +LQL E+L G L +D
Sbjct: 1056 AKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARG----------DDETLH 1105
Query: 235 QYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQI--------FPV 286
+ NAL V +R++ Q +D + + + +Q+ + +
Sbjct: 1106 KNNALKV----------VRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTEL 1155
Query: 287 DSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHL 346
+ +DT + + ++ E A + LEE + E+ +D T L+ SE L
Sbjct: 1156 EDTLDTTAAQQELRTKREQEVAELKKALEEETKN-HEAQIQDMRQRHATA--LEELSEQL 1212
Query: 347 TSYICFLRKILPYQLKSLEEECESSLC-TSALRARNLELSQDMKKMTAVFEKLQTYIA-- 403
F + L + LE + + C L+ E KK+ A ++L ++
Sbjct: 1213 EQAKRF-KANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEG 1271
Query: 404 -LLALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKL 462
L + E L+ +V T + A KD + SQ + L T++
Sbjct: 1272 DRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQK 1331
Query: 463 ITTNDCILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYKK 522
+ + I L+ SL + L + +L +
Sbjct: 1332 LNLSSRI-------------------RQLEEEKNSLQEQQEEEEEARKNLEKQ-VLALQS 1371
Query: 523 KAAAYMKSLRKPLLESVPYEEALANRRILLSSTESREGLAQQVQQSLEKISKLEQEKEHW 582
+ A K + L EEA ++ LL E+ L+Q++++ KLE+ K
Sbjct: 1372 QLADTKKKVDDDLGTIESLEEA---KKKLLKDAEA---LSQRLEEKALAYDKLEKTKNR- 1424
Query: 583 MLEAQLAKIKLEKENQR-IADKLKNTGSAQLVGLAQENAAVSNTAGQ-DEATAKAVLEPI 640
L+ +L + ++ ++QR +A L+ LA+E + + A + D A A+A +
Sbjct: 1425 -LQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKET 1483
Query: 641 QSTSLVPDVESREDLIKNHYMARIVELTSQLQ-LADSKSVHFYAECRALSKRLALAEKSK 699
++ SL +E + K + + +L + ++ L SK + K + EKSK
Sbjct: 1484 KALSLARALEEALE-AKEEFERQNKQLRADMEDLMSSKD--------DVGKNVHELEKSK 1534
Query: 700 EALTEEMKLASQNISRLQDELTTT---KRSYEDQLSMMSDHLCSMNETLSKQREE 751
AL ++++ + L+DEL T K E + M +T +Q EE
Sbjct: 1535 RALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEE 1589
Score = 48.9 bits (115), Expect = 2e-05
Identities = 141/737 (19%), Positives = 292/737 (39%), Gaps = 94/737 (12%)
Query: 67 LQLAKRVELLQ--DELALSEPRGKKNKKSGESSS-----QLSQEQKSVFDEDLQKKIEEN 119
LQ+ ++ E LQ DE L + + K+ K GE Q E+K++ E LQ + E
Sbjct: 845 LQVTRQEEELQAKDE-ELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETE-- 901
Query: 120 ERLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKL 179
F EA+E +R+RLA + E + ++ + E + LQN+K K+
Sbjct: 902 -----LFAEAEE--------MRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKM 948
Query: 180 EVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNAL 239
+ Q LE++ E ++ QL+ T + ++EE + ++ ++ N + +
Sbjct: 949 QAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIK-KMEEEILLLEDQ---NSKFIKEKKLM 1004
Query: 240 NVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAIDTISPLNQK 299
+ QL + + LA +++ +Q + I ++ + Q+
Sbjct: 1005 EDRIAECSSQLAEEEEKAKNLAKIRN------------KQEVMISDLEERLKKEEKTRQE 1052
Query: 300 FSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLK-------TFSEHLTSYICF 352
+ + L++ + L I E + + + +L+ + H + +
Sbjct: 1053 LEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKV 1112
Query: 353 LRKILPYQLKSLEEECESSLCT-SALRARNLELSQDMKKM-TAVFEKLQTYIALLALPST 410
+R+ L Q+ L+E+ ES + + + +LS++++ + T + + L T A L +
Sbjct: 1113 VRE-LQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTK 1171
Query: 411 EPDGL--LRTNYSSVLTNVGAALHGFHD----VMKDISKHYSQKAAIEHELPTATQKLIT 464
+ L+ N A + ++++S+ Q + L Q L T
Sbjct: 1172 REQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLET 1231
Query: 465 TNDCILSSVVALTNGAGKIASFFSNNLDYFI----ASLSYGPKAASGFISPLS------- 513
N + V L + + LD + A +S G + S
Sbjct: 1232 DNKELACEVKVLQQVKAE-SEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELD 1290
Query: 514 --AECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLSSTESREGLAQQVQQSLEK 571
+ + + +KK + K LES + + +L T + L+ +++Q E+
Sbjct: 1291 NVSTLLEEAEKKGIKFAKDAAS--LES----QLQDTQELLQEETRQKLNLSSRIRQLEEE 1344
Query: 572 ISKLEQEKEHWMLEAQLAKIKLEKENQRIADKLKNTGSA--QLVGLAQENAAVSNTAGQD 629
+ L++++E E + A+ LEK+ + +L +T +G + +D
Sbjct: 1345 KNSLQEQQE----EEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKD 1400
Query: 630 EATAKAVLEPIQSTSLVPD-VESREDLIKNHYMARIVELTSQLQLADS------KSVHFY 682
A+A+ + ++ +L D +E ++ ++ V+L Q Q+A + K
Sbjct: 1401 ---AEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLL 1457
Query: 683 AECRALSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYE---DQLSMMSDHLC 739
AE +++S R A EA E + + +++R +E K +E QL + L
Sbjct: 1458 AEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLM 1517
Query: 740 SMNETLSKQREEIDTLK 756
S + + K E++ K
Sbjct: 1518 SSKDDVGKNVHELEKSK 1534
Score = 47.8 bits (112), Expect = 4e-05
Identities = 144/833 (17%), Positives = 312/833 (37%), Gaps = 115/833 (13%)
Query: 5 ELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTF 64
ELQ + +L +++ +A +K D ALK +L + +L + + T
Sbjct: 1115 ELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTEL---EDTLDTTAAQQELRTK 1171
Query: 65 RNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHI 124
R ++A+ + L++E K+ E+ Q +++ + E+L +++E+ +R
Sbjct: 1172 REQEVAELKKALEEET-----------KNHEAQIQDMRQRHATALEELSEQLEQAKRFKA 1220
Query: 125 QFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKL-QNDKAKLEV-- 181
+ + + EL + L+ A+ + L + E K+ + D+ ++E+
Sbjct: 1221 NLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAE 1280
Query: 182 KSQTLEKEAKECRLRTEECQLQLKTLHED---LSGRLEESLSIINEKVPFNDTKYSQYNA 238
K+ L+ E EE + + +D L +L+++ ++ E+ S+
Sbjct: 1281 KASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQ 1340
Query: 239 LNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAIDTISPLNQ 298
L ++ + Q + + A + L + V AL + T+++ VD + TI L +
Sbjct: 1341 LEEEKNSLQEQQEEEEEARKNL---EKQVLALQSQLADTKKK-----VDDDLGTIESLEE 1392
Query: 299 K----------FSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTS 348
SQ L E A LE+ L + + + TV + +
Sbjct: 1393 AKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKK 1452
Query: 349 YICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALP 408
+ L + + EE + + L L++ +++ E+ +
Sbjct: 1453 FDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFE--------- 1503
Query: 409 STEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDC 468
+ LR + ++++ H++ K Q + +L +L T D
Sbjct: 1504 --RQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDA 1561
Query: 469 ILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAAY- 527
L V + + + F +L + + L AE + K++A A
Sbjct: 1562 KLRLEVNMQ----AMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVA 1617
Query: 528 --------------------------MKSLRKPLLESVPYEEALANRRILLSSTESREGL 561
+K LRK + Y+ L R SR+ +
Sbjct: 1618 SKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARA------SRDEI 1671
Query: 562 AQQVQQSLEKISKLEQE---KEHWMLEAQLAKIKLEKENQRIADKLKNTGSAQLVGLAQE 618
Q ++S +K+ LE E + + ++ A+ E+E +AD++ N+ S + L ++
Sbjct: 1672 FAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEK 1731
Query: 619 N------AAVSNTAGQDEATAKAVLEPIQSTSLVPDVESRE-----------DLIKNHYM 661
A + ++++ + + + + T+L D + E D +
Sbjct: 1732 RRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLE 1791
Query: 662 ARIVELTSQLQ-LADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDEL 720
+ EL ++LQ L + F A AL ++ E+ E +E A++ + R + +L
Sbjct: 1792 RQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKL 1851
Query: 721 ------TTTKRSYEDQLSMMSDHLCSMNETLSKQREEIDTLKMSSKGNSKKNK 767
+R + DQ + + + L +Q EE + + +++ N+ + K
Sbjct: 1852 KEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAE--EEATRANASRRK 1902
Score = 38.1 bits (87), Expect = 0.031
Identities = 28/117 (23%), Positives = 49/117 (41%), Gaps = 7/117 (5%)
Query: 9 KYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQ-------SLRKLQQEMDS 61
K +++ + R K+ + A LK QL+ ++ S RKLQ+E+D
Sbjct: 1850 KLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDD 1909
Query: 62 LTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEE 118
T N L++ V L++ L P + +SG L + D+D + K +
Sbjct: 1910 ATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRRQLHLEGASLELSDDDTESKTSD 1966
Score = 35.8 bits (81), Expect = 0.15
Identities = 50/238 (21%), Positives = 94/238 (39%), Gaps = 15/238 (6%)
Query: 28 KKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQDELALSEPRG 87
K ++DE+ A QL ++ L + Q M+ L R + +V+ L ELA
Sbjct: 1724 KSALLDEKRRLEARIAQL---EEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAA 1780
Query: 88 KKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEAD--EQHKHVEAELRSRLA 145
+K+ + + + ++E K+ E L+ ++ + I EA + + +E E + R A
Sbjct: 1781 QKSDNARQQLERQNKELKAKLQE-LEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAA 1839
Query: 146 T------LETEAAQHQAVVDGLTR---KYMETIEKLQNDKAKLEVKSQTLEKEAKECRLR 196
E + + V+ R +Y E +EK +L+ + + E+EA
Sbjct: 1840 ANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANAS 1899
Query: 197 TEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRD 254
+ Q +L E G E ++ N +S + LH L++ D
Sbjct: 1900 RRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRRQLHLEGASLELSD 1957
>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 2 [Homo sapiens]
Length = 1403
Score = 61.2 bits (147), Expect = 3e-09
Identities = 156/783 (19%), Positives = 316/783 (40%), Gaps = 104/783 (13%)
Query: 5 ELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTF 64
+L+ KY+ + E KLR Q + + V + + + L E+ K + L + E +
Sbjct: 535 DLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEMEREKKGR 594
Query: 65 RNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHI 124
+ ++ + + L +LALS P K S++++++ KK+ E ER H
Sbjct: 595 KVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEK---------AKKLVEMEREH- 644
Query: 125 QFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQ 184
E+ +L+ L ++ + AQH E+ + K++LE KS
Sbjct: 645 ------EKSLSEIRQLKRELENVKAKLAQHVKP------------EEHEQVKSRLEQKSG 686
Query: 185 TLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALNVPLH 244
L K+ E L+ + Q ++ EKV + D K + A N+ +
Sbjct: 687 ELGKKITELTLKNQTLQKEI-------------------EKV-YLDNKLLKEQAHNLTIE 726
Query: 245 NRRHQLKMR---DIAGQALAFVQDLVTALLNF-HTYTEQRIQ----IFPVDSAIDTISPL 296
+ H + ++ D+ A + DL LL+ YTE++++ + DS +S L
Sbjct: 727 MKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRL 786
Query: 297 NQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSYICFLRKI 356
F ++ + L+ ++ L + ++E E K+ LTS L+K+
Sbjct: 787 ETVFVP-PEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEKIHA----LTSENTNLKKM 841
Query: 357 LPYQLKSLE--EECESSLCTSALRARNLELSQDMKKMTAV---FEKLQTYIALLALPSTE 411
+ Q ++ EE + +L L N EL KK + F K++ +L
Sbjct: 842 MSNQYVPVKTHEEVKMTL-NDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLEN 900
Query: 412 PDGLLRTNYSSV------LTNVGAALHGFHDVMKDISKHY----SQKAAIEHELPTATQK 461
++ Y S+ ++++ ++ D +I +Y + + E+ ++
Sbjct: 901 TQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLHAEIKAQKKE 960
Query: 462 LITTNDCI---LSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECML 518
L T +CI + +V+ K + D LS + S +S +
Sbjct: 961 LDTIQECIKVKYAPIVSFEECERKFKATEKELKD----QLSEQTQKYS--VSEEEVKKNK 1014
Query: 519 QYKKKAAAYMKSLRKPLLE-SVPYEEALANRRILLSSTESREGLAQQVQQSLEKI----S 573
Q K + +L+K L + +V E++ R L T+ + + Q ++
Sbjct: 1015 QENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKE 1074
Query: 574 KLEQEKEHWMLEAQLAKIKLEKENQRI--ADKLKNTGSAQLVGLAQENAAVSNTAGQDEA 631
KL +E E + L+K++ + + LK + + + L +E ++ +++
Sbjct: 1075 KLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQ 1134
Query: 632 TAKAVLEPI--QSTSLVPDVESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALS 689
T + + + Q S VP E + IK + + + + L+ + +S + E +S
Sbjct: 1135 TVTKLHQLLENQKNSSVPLAEHLQ--IKEAFEKEVGIIKASLREKEEESQNKMEE---VS 1189
Query: 690 KRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSKQR 749
K + + +K+AL KL ++ + L + TK E Q+S +++ L ++N +
Sbjct: 1190 KLQSEVQNTKQAL---KKLETREVVDL-SKYKATKSDLETQISSLNEKLANLNRKYEEVC 1245
Query: 750 EEI 752
EE+
Sbjct: 1246 EEV 1248
Score = 51.6 bits (122), Expect = 3e-06
Identities = 82/415 (19%), Positives = 169/415 (40%), Gaps = 53/415 (12%)
Query: 5 ELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTF 64
+++ K++ + QE+ K++ +N++LK+ + + Q A L + + L Q M +
Sbjct: 872 DVKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQD 931
Query: 65 RNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHI 124
N ++ Q+E+ K KK ++ +Q+ I+ +
Sbjct: 932 SNAEILANYRKGQEEIVTLHAEIKAQKKELDT---------------IQECIKVKYAPIV 976
Query: 125 QFFEADEQHKHVEAELRSRL-------ATLETEAAQHQAVVDGLTRKYMETIEKLQNDKA 177
F E + + K E EL+ +L + E E +++ D L +K + T++K DK
Sbjct: 977 SFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKL-KKEIFTLQKDLRDKT 1035
Query: 178 KLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYN 237
L KS +E+ +T+E QLK DLS + E ++ + V N + S+
Sbjct: 1036 VLIEKSHEMERALSR---KTDELNKQLK----DLSQKYTEVKNVKEKLVEENAKQTSEIL 1088
Query: 238 ALNVPLHNRRHQLKMRDIAGQAL-AFVQDLVTALLNF-HTYTEQRIQIFPVDSAIDTISP 295
A+ L + L+ + ++L +++L L + Y +++ + + ++
Sbjct: 1089 AVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQLLENQKN 1148
Query: 296 LNQKFSQYLHENASY----------VRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEH 345
+ +++L ++ +R EE + E +++ V T LK
Sbjct: 1149 SSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLETR 1208
Query: 346 ----LTSYICFLRKILPYQLKSLEEECES------SLCTSALRARNLELSQDMKK 390
L+ Y + L Q+ SL E+ + +C L A+ E+S +K
Sbjct: 1209 EVVDLSKYKA-TKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEISAKDEK 1262
Score = 43.1 bits (100), Expect = 0.001
Identities = 150/774 (19%), Positives = 303/774 (39%), Gaps = 115/774 (14%)
Query: 4 AELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLT 63
+ L+ K +L ++ ++L +NQ L+K + ++ LKEQ
Sbjct: 679 SRLEQKSGELGKKITELTLKNQTLQKEIEKVYLDNKLLKEQA------------------ 720
Query: 64 FRNLQLAKRVELLQDELALSEPRGKKNKKSGES-SSQLSQEQKSVFDEDLQKKIEENERL 122
NL + + + L +SE KKS ++ L+++ V + +KK+E + L
Sbjct: 721 -HNLTIEMKNHYV--PLKVSEDM----KKSHDAIIDDLNRKLLDVTQKYTEKKLEMEKLL 773
Query: 123 HIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKL--- 179
E D K V SRL T+ +H+ + L +E ++L K K
Sbjct: 774 ----LENDSLSKDV-----SRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGED 824
Query: 180 EVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNAL 239
+ K L E + + +KT HE++ L ++L+ N ++ K+ N
Sbjct: 825 QEKIHALTSENTNLKKMMSNQYVPVKT-HEEVKMTLNDTLAKTNRELLDVKKKFEDINQE 883
Query: 240 NVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAIDTISPLNQK 299
V + ++ LK + L Q+ + A + + E ++ + ++ + N +
Sbjct: 884 FVKIKDKNEILK------RNLENTQNQIKA--EYISLAEHEAKMSSLSQSMRKVQDSNAE 935
Query: 300 FSQYLHENASYVRPLEEGM-LHLFESITEDTVTVLETTVKLKTFSEHLTSYICFLRKILP 358
A+Y + EE + LH + + ++ +K+K ++ ++ C
Sbjct: 936 IL------ANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVK-YAPIVSFEEC------E 982
Query: 359 YQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRT 418
+ K+ E+E + L + E +++KK +KL+ I L + L+
Sbjct: 983 RKFKATEKELKDQLSEQTQKYSVSE--EEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEK 1040
Query: 419 NYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTN 478
++ + + + +KD+S+ Y+ E+ +KL+ N S ++A+ N
Sbjct: 1041 SH-EMERALSRKTDELNKQLKDLSQKYT-------EVKNVKEKLVEENAKQTSEILAVQN 1092
Query: 479 GAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQ---YKKKAAAY-------- 527
+ + K+ +G I L E Y+K+
Sbjct: 1093 --------LLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQLLE 1144
Query: 528 -MKSLRKPLLESVPYEEALANR-RILLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLE 585
K+ PL E + +EA I+ +S +E ++ Q +E++SKL+ E ++
Sbjct: 1145 NQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKE---EESQNKMEEVSKLQSEVQN---- 1197
Query: 586 AQLAKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSL 645
+ A KLE K K T S ++ N ++N + E + VL +
Sbjct: 1198 TKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKK--- 1254
Query: 646 VPDVESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEE 705
++ ++++ H+ E+ Q + D KS+ E L +R+ + K EA +
Sbjct: 1255 --EISAKDEKELLHFSIE-QEIKDQKERCD-KSLTTITE---LQRRIQESAKQIEAKDNK 1307
Query: 706 MKLASQNISRLQ------DELTTTKRSYEDQLSMMSDHLCSMNETLSKQREEID 753
+ ++ RL+ +LT T + + S + D L ++L +Q + D
Sbjct: 1308 ITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLADAD 1361
>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 1 [Homo sapiens]
Length = 1416
Score = 61.2 bits (147), Expect = 3e-09
Identities = 156/783 (19%), Positives = 316/783 (40%), Gaps = 104/783 (13%)
Query: 5 ELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTF 64
+L+ KY+ + E KLR Q + + V + + + L E+ K + L + E +
Sbjct: 548 DLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEMEREKKGR 607
Query: 65 RNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHI 124
+ ++ + + L +LALS P K S++++++ KK+ E ER H
Sbjct: 608 KVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEK---------AKKLVEMEREH- 657
Query: 125 QFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQ 184
E+ +L+ L ++ + AQH E+ + K++LE KS
Sbjct: 658 ------EKSLSEIRQLKRELENVKAKLAQHVKP------------EEHEQVKSRLEQKSG 699
Query: 185 TLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALNVPLH 244
L K+ E L+ + Q ++ EKV + D K + A N+ +
Sbjct: 700 ELGKKITELTLKNQTLQKEI-------------------EKV-YLDNKLLKEQAHNLTIE 739
Query: 245 NRRHQLKMR---DIAGQALAFVQDLVTALLNF-HTYTEQRIQ----IFPVDSAIDTISPL 296
+ H + ++ D+ A + DL LL+ YTE++++ + DS +S L
Sbjct: 740 MKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRL 799
Query: 297 NQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSYICFLRKI 356
F ++ + L+ ++ L + ++E E K+ LTS L+K+
Sbjct: 800 ETVFVP-PEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEKIHA----LTSENTNLKKM 854
Query: 357 LPYQLKSLE--EECESSLCTSALRARNLELSQDMKKMTAV---FEKLQTYIALLALPSTE 411
+ Q ++ EE + +L L N EL KK + F K++ +L
Sbjct: 855 MSNQYVPVKTHEEVKMTL-NDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLEN 913
Query: 412 PDGLLRTNYSSV------LTNVGAALHGFHDVMKDISKHY----SQKAAIEHELPTATQK 461
++ Y S+ ++++ ++ D +I +Y + + E+ ++
Sbjct: 914 TQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLHAEIKAQKKE 973
Query: 462 LITTNDCI---LSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECML 518
L T +CI + +V+ K + D LS + S +S +
Sbjct: 974 LDTIQECIKVKYAPIVSFEECERKFKATEKELKD----QLSEQTQKYS--VSEEEVKKNK 1027
Query: 519 QYKKKAAAYMKSLRKPLLE-SVPYEEALANRRILLSSTESREGLAQQVQQSLEKI----S 573
Q K + +L+K L + +V E++ R L T+ + + Q ++
Sbjct: 1028 QENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKE 1087
Query: 574 KLEQEKEHWMLEAQLAKIKLEKENQRI--ADKLKNTGSAQLVGLAQENAAVSNTAGQDEA 631
KL +E E + L+K++ + + LK + + + L +E ++ +++
Sbjct: 1088 KLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQ 1147
Query: 632 TAKAVLEPI--QSTSLVPDVESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALS 689
T + + + Q S VP E + IK + + + + L+ + +S + E +S
Sbjct: 1148 TVTKLHQLLENQKNSSVPLAEHLQ--IKEAFEKEVGIIKASLREKEEESQNKMEE---VS 1202
Query: 690 KRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSKQR 749
K + + +K+AL KL ++ + L + TK E Q+S +++ L ++N +
Sbjct: 1203 KLQSEVQNTKQAL---KKLETREVVDL-SKYKATKSDLETQISSLNEKLANLNRKYEEVC 1258
Query: 750 EEI 752
EE+
Sbjct: 1259 EEV 1261
Score = 51.6 bits (122), Expect = 3e-06
Identities = 82/415 (19%), Positives = 169/415 (40%), Gaps = 53/415 (12%)
Query: 5 ELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTF 64
+++ K++ + QE+ K++ +N++LK+ + + Q A L + + L Q M +
Sbjct: 885 DVKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQD 944
Query: 65 RNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHI 124
N ++ Q+E+ K KK ++ +Q+ I+ +
Sbjct: 945 SNAEILANYRKGQEEIVTLHAEIKAQKKELDT---------------IQECIKVKYAPIV 989
Query: 125 QFFEADEQHKHVEAELRSRL-------ATLETEAAQHQAVVDGLTRKYMETIEKLQNDKA 177
F E + + K E EL+ +L + E E +++ D L +K + T++K DK
Sbjct: 990 SFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKL-KKEIFTLQKDLRDKT 1048
Query: 178 KLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYN 237
L KS +E+ +T+E QLK DLS + E ++ + V N + S+
Sbjct: 1049 VLIEKSHEMERALSR---KTDELNKQLK----DLSQKYTEVKNVKEKLVEENAKQTSEIL 1101
Query: 238 ALNVPLHNRRHQLKMRDIAGQAL-AFVQDLVTALLNF-HTYTEQRIQIFPVDSAIDTISP 295
A+ L + L+ + ++L +++L L + Y +++ + + ++
Sbjct: 1102 AVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQLLENQKN 1161
Query: 296 LNQKFSQYLHENASY----------VRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEH 345
+ +++L ++ +R EE + E +++ V T LK
Sbjct: 1162 SSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLETR 1221
Query: 346 ----LTSYICFLRKILPYQLKSLEEECES------SLCTSALRARNLELSQDMKK 390
L+ Y + L Q+ SL E+ + +C L A+ E+S +K
Sbjct: 1222 EVVDLSKYKA-TKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEISAKDEK 1275
Score = 43.1 bits (100), Expect = 0.001
Identities = 150/774 (19%), Positives = 303/774 (39%), Gaps = 115/774 (14%)
Query: 4 AELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLT 63
+ L+ K +L ++ ++L +NQ L+K + ++ LKEQ
Sbjct: 692 SRLEQKSGELGKKITELTLKNQTLQKEIEKVYLDNKLLKEQA------------------ 733
Query: 64 FRNLQLAKRVELLQDELALSEPRGKKNKKSGES-SSQLSQEQKSVFDEDLQKKIEENERL 122
NL + + + L +SE KKS ++ L+++ V + +KK+E + L
Sbjct: 734 -HNLTIEMKNHYV--PLKVSEDM----KKSHDAIIDDLNRKLLDVTQKYTEKKLEMEKLL 786
Query: 123 HIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKL--- 179
E D K V SRL T+ +H+ + L +E ++L K K
Sbjct: 787 ----LENDSLSKDV-----SRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGED 837
Query: 180 EVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNAL 239
+ K L E + + +KT HE++ L ++L+ N ++ K+ N
Sbjct: 838 QEKIHALTSENTNLKKMMSNQYVPVKT-HEEVKMTLNDTLAKTNRELLDVKKKFEDINQE 896
Query: 240 NVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAIDTISPLNQK 299
V + ++ LK + L Q+ + A + + E ++ + ++ + N +
Sbjct: 897 FVKIKDKNEILK------RNLENTQNQIKA--EYISLAEHEAKMSSLSQSMRKVQDSNAE 948
Query: 300 FSQYLHENASYVRPLEEGM-LHLFESITEDTVTVLETTVKLKTFSEHLTSYICFLRKILP 358
A+Y + EE + LH + + ++ +K+K ++ ++ C
Sbjct: 949 IL------ANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVK-YAPIVSFEEC------E 995
Query: 359 YQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRT 418
+ K+ E+E + L + E +++KK +KL+ I L + L+
Sbjct: 996 RKFKATEKELKDQLSEQTQKYSVSE--EEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEK 1053
Query: 419 NYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTN 478
++ + + + +KD+S+ Y+ E+ +KL+ N S ++A+ N
Sbjct: 1054 SH-EMERALSRKTDELNKQLKDLSQKYT-------EVKNVKEKLVEENAKQTSEILAVQN 1105
Query: 479 GAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQ---YKKKAAAY-------- 527
+ + K+ +G I L E Y+K+
Sbjct: 1106 --------LLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQLLE 1157
Query: 528 -MKSLRKPLLESVPYEEALANR-RILLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLE 585
K+ PL E + +EA I+ +S +E ++ Q +E++SKL+ E ++
Sbjct: 1158 NQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKE---EESQNKMEEVSKLQSEVQN---- 1210
Query: 586 AQLAKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSL 645
+ A KLE K K T S ++ N ++N + E + VL +
Sbjct: 1211 TKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKK--- 1267
Query: 646 VPDVESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEE 705
++ ++++ H+ E+ Q + D KS+ E L +R+ + K EA +
Sbjct: 1268 --EISAKDEKELLHFSIE-QEIKDQKERCD-KSLTTITE---LQRRIQESAKQIEAKDNK 1320
Query: 706 MKLASQNISRLQ------DELTTTKRSYEDQLSMMSDHLCSMNETLSKQREEID 753
+ ++ RL+ +LT T + + S + D L ++L +Q + D
Sbjct: 1321 ITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLADAD 1374
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 59.7 bits (143), Expect = 1e-08
Identities = 60/222 (27%), Positives = 95/222 (42%), Gaps = 26/222 (11%)
Query: 19 KLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRV----- 73
KL ++ ++ V D + L+E+LK KD L +L ++ Q+ K++
Sbjct: 1103 KLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQA 1162
Query: 74 --ELLQDEL-ALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEAD 130
E L++EL A R + K+ E++ +L E+L +++EE E
Sbjct: 1163 RAEELEEELEAERAARARVEKQRAEAAREL---------EELSERLEEAGGASAGQREGC 1213
Query: 131 EQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEA 190
+ EAEL LE A +H+A V L RK E +L L+ Q LEKE
Sbjct: 1214 RKR---EAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEK 1270
Query: 191 KECRLRTEECQLQLKTL------HEDLSGRLEESLSIINEKV 226
E R+ ++ ++TL E L E+ LS KV
Sbjct: 1271 SELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKV 1312
Score = 53.1 bits (126), Expect = 9e-07
Identities = 50/224 (22%), Positives = 108/224 (48%), Gaps = 24/224 (10%)
Query: 13 LAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKR 72
LA KL + LKK + D + A +++ + + ++ L +EM +L +L K
Sbjct: 985 LAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKE 1044
Query: 73 VELLQD--ELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEAD 130
+ LQ+ + AL + + ++++ S + ++L EQ+ EDL+ +E+ ++L + + +
Sbjct: 1045 KKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQV---EDLECSLEQEKKLRM---DTE 1098
Query: 131 EQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIE-------------KLQNDKA 177
+ +E +L+ ++ A Q + + L +K E + ++Q
Sbjct: 1099 RAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIK 1158
Query: 178 KLEVKSQTLEKE---AKECRLRTEECQLQLKTLHEDLSGRLEES 218
+L+ +++ LE+E + R R E+ + + E+LS RLEE+
Sbjct: 1159 ELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEA 1202
Score = 38.5 bits (88), Expect = 0.024
Identities = 52/243 (21%), Positives = 93/243 (38%), Gaps = 47/243 (19%)
Query: 533 KPLLESVPYEEALANRRILLSSTESREGLAQQVQQSLEKIS-KLEQEKEHWMLEAQLAKI 591
KPLL S EE LA R L A+ +Q LE+ + QEK L+ Q +
Sbjct: 886 KPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQD 945
Query: 592 KLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVES 651
L +R +K+ QL G +E L +E
Sbjct: 946 NLADAEERCHLLIKS--KVQLEGKVKE--------------------------LSERLED 977
Query: 652 REDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEA-------LTE 704
E++ +L ++ + + + + L LA AEK K+A LTE
Sbjct: 978 EEEVN--------ADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQATENKVKNLTE 1029
Query: 705 EMKLASQNISRLQDELTTTKRSYEDQLSMM---SDHLCSMNETLSKQREEIDTLKMSSKG 761
EM ++++RL E + +++ L + D + ++ + + ++++ L+ S +
Sbjct: 1030 EMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQ 1089
Query: 762 NSK 764
K
Sbjct: 1090 EKK 1092
Score = 37.7 bits (86), Expect = 0.041
Identities = 135/741 (18%), Positives = 281/741 (37%), Gaps = 114/741 (15%)
Query: 35 QANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQDELALSEPR-------- 86
+A L+ L + ++L++ S+T LA +++ QD LA +E R
Sbjct: 902 RAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHLLIKSK 961
Query: 87 ----GKKNKKS------GESSSQLSQEQKSVFDE--DLQKKIEENERLHIQFFEADEQHK 134
GK + S E ++ L+ ++ + DE +L+K I++ L + +A+++ +
Sbjct: 962 VQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDD---LKLTLAKAEKEKQ 1018
Query: 135 HVEAELRS---RLATLETEAAQHQAVVDGLTRKYMETIEKLQND--------KAKLEVKS 183
E ++++ +A L+ A+ L + + + LQ + KAKL ++
Sbjct: 1019 ATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQ 1078
Query: 184 Q------TLEKEAKECRLRTEECQLQ----LKTLHEDLSGRLEESLSIINEKVPFNDTKY 233
Q +LE+E K+ R+ TE + + LK E ++ ++ + EK+ D++
Sbjct: 1079 QVEDLECSLEQE-KKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQ-LEEKLKKKDSEL 1136
Query: 234 SQYN--ALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAID 291
SQ + + L + Q K++++ +A ++L +QR + A
Sbjct: 1137 SQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAE------AAR 1190
Query: 292 TISPLNQKFSQYLHENASY---VRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTS 348
+ L+++ + +A R E + L + E + T L+
Sbjct: 1191 ELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRR------- 1243
Query: 349 YICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALP 408
K E E +L+ +L ++ ++ + L + L
Sbjct: 1244 -------------KQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRA 1290
Query: 409 STEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDC 468
+ L RT Y L+ + + D S + EL +L+ +C
Sbjct: 1291 KASAEKLCRT-YEDQLSEAKIKVEELQRQLADASTQRGRLQTESGEL----SRLLEEKEC 1345
Query: 469 ILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAAYM 528
++S + GK + + +L+ L KA S L + +A +
Sbjct: 1346 LISQL-----SRGK--ALAAQSLEELRRQLEEESKAKSA----------LAHAVQALRHD 1388
Query: 529 KSLRKPLLESVPYEEALANRRILLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEAQL 588
L + E +A R + ++ E + ++ ++++ +LE+ K+ L Q
Sbjct: 1389 CDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQE 1448
Query: 589 AKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVPD 648
A+ +E N + + S + L + + T + AT+ A + L
Sbjct: 1449 AEEGVEAANAKCS-------SLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERA 1501
Query: 649 VESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKL 708
+E R + E+ +L+ A +S E L A ++ E L E K
Sbjct: 1502 LEERR--------RQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKN 1553
Query: 709 ASQNISRLQDELTTTKRSYED 729
+ IS L D+++ + +S ++
Sbjct: 1554 LQEEISDLTDQVSLSGKSIQE 1574
Score = 32.7 bits (73), Expect = 1.3
Identities = 43/226 (19%), Positives = 91/226 (40%), Gaps = 28/226 (12%)
Query: 556 ESREGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEK-------ENQRIADKLKNTG 608
E + L Q+Q+ ++++ +E E + + A+ ++EK E + ++++L+ G
Sbjct: 1144 EDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAG 1203
Query: 609 SA---QLVGLAQENA-------AVSNTAGQDEAT--------AKAVLEPIQSTSLVPDVE 650
A Q G + A + A + EAT A+ E + + V
Sbjct: 1204 GASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVR 1263
Query: 651 SREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLAS 710
+ + K+ + +L + ++ CR +L+ A+ E L ++ AS
Sbjct: 1264 QKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADAS 1323
Query: 711 QNISRLQDELTTTKRSYEDQ---LSMMSDHLCSMNETLSKQREEID 753
RLQ E R E++ +S +S ++L + R +++
Sbjct: 1324 TQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLE 1369
Score = 32.3 bits (72), Expect = 1.7
Identities = 51/184 (27%), Positives = 86/184 (46%), Gaps = 44/184 (23%)
Query: 3 SAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAAL---KEQLKMKDQSLRKLQQEM 59
SA L+ + L Q +L+A+ E+A AAL K+Q++ + +R+L+ E+
Sbjct: 1825 SAHLERMKKTLEQTVRELQARL---------EEAEQAALRGGKKQVQKLEAKVRELEAEL 1875
Query: 60 DSLTFRNLQLAKRV---ELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKI 116
D+ ++ + K V E ELA +KN L++ Q V + LQ K+
Sbjct: 1876 DAEQKKHAEALKGVRKHERRVKELAYQAEEDRKN---------LARMQDLV--DKLQSKV 1924
Query: 117 EENERLHIQFFEADE------------QHKHVEAELRSRLATLETEAAQHQA-VVDGLTR 163
+ +R QF EA++ QH+ +AE R+ +A ET+A + +A D L
Sbjct: 1925 KSYKR---QFEEAEQQANTNLAKYRKAQHELDDAEERADMA--ETQANKLRARTRDALGP 1979
Query: 164 KYME 167
K+ E
Sbjct: 1980 KHKE 1983
Score = 31.6 bits (70), Expect = 2.9
Identities = 46/222 (20%), Positives = 92/222 (41%), Gaps = 23/222 (10%)
Query: 9 KYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLT-FRN- 66
K ++ E S+++A+ + + + ++ A L+ +++ LQ +D+ T RN
Sbjct: 1606 KTLRIQLELSQVKAE---VDRKLAEKDEECANLRRN---HQRAVESLQASLDAETRARNE 1659
Query: 67 -LQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQ 125
L+L K++E ++L L + +++++L Q Q ++ Q +E +RL +
Sbjct: 1660 ALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQL----KEEQAGRDEEQRLAAE 1715
Query: 126 FFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQ----------ND 175
E + + + L + L L Q + ++ +E E+L N
Sbjct: 1716 LHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQ 1775
Query: 176 KAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEE 217
K KLE L E +E E + + K D + EE
Sbjct: 1776 KKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEE 1817
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 59.3 bits (142), Expect = 1e-08
Identities = 128/674 (18%), Positives = 262/674 (38%), Gaps = 93/674 (13%)
Query: 5 ELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTF 64
E K Q+ +YS+ +N++L++ + ++ + ++KE+ + L +L++E
Sbjct: 822 ERSSKLQEELDKYSQALRKNEILRQTIEEKDRSLGSMKEENNHLQEELERLREEQS---- 877
Query: 65 RNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHI 124
R +A + L L+ + N ++ QK + D++ Q K++ + L
Sbjct: 878 RTAPVAD-PKTLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQN-QSKMQLLQSLQE 935
Query: 125 QFFEADE---QHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKL-- 179
Q E DE QH+ + A + E Q ++ + + E + +Q D + +
Sbjct: 936 QKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQ 995
Query: 180 --EVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYN 237
+V+S +E +++ L E + +K + E E + ++NEK N + Q +
Sbjct: 996 ETKVQSLNIENGSEKHDLSKAETERLVKGIKE-----RELEIKLLNEK---NISLTKQID 1047
Query: 238 ALNVPLHNRRHQ-LKMRDIAGQAL-------AFVQDLVTALLNFHTYTEQRIQIFPVDSA 289
L+ + Q ++ +D+ QAL + QD+V Y +R ++F V
Sbjct: 1048 QLSKDEVGKLTQIIQQKDLEIQALHARISSTSHTQDVVYLQQQLQAYAMEREKVFAV--- 1104
Query: 290 IDTISPLNQKFSQYLHENASYVRPLEEGMLHL----------FESITED----TVTVLET 335
++ + N H+ V E ++ L FES +D T+ L
Sbjct: 1105 LNEKTRENSHLKTEYHKMMDIVAAKEAALIKLQDENKKLSTRFESSGQDMFRETIQNLSR 1164
Query: 336 TVKLKTFSEHLTSYIC-FLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAV 394
++ K S C L +L E +S L +L Q +KKM
Sbjct: 1165 IIREKDIEIDALSQKCQTLLAVLQTSSTGNEAGGVNSNQFEELLQERDKLKQQVKKMEEW 1224
Query: 395 FEKLQTYIALLALPSTEPDGLLR----------TNYSSVLTNVGAALHGFHDVMKDISKH 444
+++ T + + S + L N S + + + + +
Sbjct: 1225 KQQVMTTVQNMQHESAQLQEELHQLQAQVLVDSDNNSKLQVDYTGLIQSYEQNETKLKNF 1284
Query: 445 YSQKAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKA 504
+ A ++H + +L T D +L LD LS
Sbjct: 1285 GQELAQVQHSI----GQLCNTKDLLL------------------GKLDIISPQLS----- 1317
Query: 505 ASGFISPLSAECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLSSTESREGLAQQ 564
++ ++P SAEC+ K + + L + LE + ++L + + + + +
Sbjct: 1318 SASLLTPQSAECLRASKSEVLSESSELLQQELEEL--RKSLQEKDATIRTLQENN---HR 1372
Query: 565 VQQSLEKISKLEQEKEHWMLEAQLAKIKLEKEN--QRIADKLKNTGSAQLVGLAQENAAV 622
+ S+ S+LE+ KEH ++++ ++K EK++ Q++ + A+ L N
Sbjct: 1373 LSDSIAATSELER-KEHEQTDSEIKQLK-EKQDVLQKLLKEKDLLIKAKSDQLLSSNENF 1430
Query: 623 SNTAGQDEATAKAV 636
+N ++E +AV
Sbjct: 1431 TNKVNENELLRQAV 1444
Score = 52.4 bits (124), Expect = 2e-06
Identities = 153/779 (19%), Positives = 296/779 (37%), Gaps = 130/779 (16%)
Query: 1 MASAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQE-M 59
+ +L+ K + L + +K + N V Q + LKE ++ ++ L +++ E M
Sbjct: 576 LTKQKLEDKVENLVDQLNKSQESN-------VSIQKENLELKEHIRQNEEELSRIRNELM 628
Query: 60 DSL------TFRNLQLAKR-VELLQDELALSE-PRGKKNKKSGESSSQLSQEQKSVFDED 111
SL F++ L +R E+ + LSE + +N K ++ E+ + ED
Sbjct: 629 QSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACED 688
Query: 112 LQKKIEE----NERLHIQFFEADEQHK----HVEAELRSRLATLETEAAQHQAVVDGLTR 163
++ ++EE N +L ++ E K +EAEL L EA +++ ++ L+
Sbjct: 689 VRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLEEANKYEKTIEELSN 748
Query: 164 KYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEES---LS 220
LQ + L +Q + E E + E+ K + LS LEE
Sbjct: 749 ARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQ 808
Query: 221 IINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQR 280
+IN+K F + + + L L L+ +I Q + E++
Sbjct: 809 LINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTI-----------------EEK 851
Query: 281 IQIFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTV-KL 339
D ++ ++ N +L E +R + + + T D+VT L + V +L
Sbjct: 852 ------DRSLGSMKEEN----NHLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQL 901
Query: 340 KTFSEHLTSYICFLRKILPYQ-------LKSLEEE--------CESSLCTSALRARNLEL 384
T EHL I +KI+ Q L+SL+E+ + + LE
Sbjct: 902 NTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEK 961
Query: 385 SQDMKKMTAVFEKLQTYI--ALLALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDIS 442
+++K + E+++T + + + D T S+ G+ H D+S
Sbjct: 962 DEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNIENGSEKH-------DLS 1014
Query: 443 KHYSQ---KAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNNLDYFIASLS 499
K ++ K E EL KL+ + ++LT +++ L I
Sbjct: 1015 KAETERLVKGIKERELEI---KLLNEKN------ISLTKQIDQLSKDEVGKLTQIIQQKD 1065
Query: 500 YGPKAASGFISPLS-AECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLSSTESR 558
+A IS S + ++ +++ AY K +L T
Sbjct: 1066 LEIQALHARISSTSHTQDVVYLQQQLQAYAMEREKVF-------------AVLNEKTREN 1112
Query: 559 EGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRIADKLKNTGS-------AQ 611
L + + ++ ++ E A IKL+ EN++++ + +++G
Sbjct: 1113 SHLKTEYHKMMDIVAAKE-----------AALIKLQDENKKLSTRFESSGQDMFRETIQN 1161
Query: 612 LVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVESR--EDLIKNHYMARIVELTS 669
L + +E + Q T AVL+ + + V S E+L++ +L
Sbjct: 1162 LSRIIREKDIEIDALSQKCQTLLAVLQTSSTGNEAGGVNSNQFEELLQER-----DKLKQ 1216
Query: 670 QLQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYE 728
Q++ + + + A ++ L ++ + S N S+LQ + T +SYE
Sbjct: 1217 QVKKMEEWKQQVMTTVQNMQHESAQLQEELHQLQAQVLVDSDNNSKLQVDYTGLIQSYE 1275
Score = 48.9 bits (115), Expect = 2e-05
Identities = 136/794 (17%), Positives = 310/794 (39%), Gaps = 85/794 (10%)
Query: 16 EYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVEL 75
E ++ AQ+ +++ +QA S A E ++ L L Q+ +SL NL+L R+E+
Sbjct: 373 EKERILAQSASVEEVFRLQQALSDAENEIMR-----LSSLNQD-NSLAEDNLKLKMRIEV 426
Query: 76 LQDELALSEPRGKKNKKS------------GESSSQLSQEQK--------SVFDEDLQKK 115
L+ E +L ++ + S ++ +S + + +++L +
Sbjct: 427 LEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQELNQS 486
Query: 116 IEENERLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQND 175
I E E L + E D Q++ E + ++ + ++ Q D + K + + +
Sbjct: 487 ISEKETLIAEIEELDRQNQ----EATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKR 542
Query: 176 KAKLEVKSQTLEKEAKECRLRTEECQLQLKTLH---EDLSGRLEESLSIINEKVPFNDTK 232
+LE + KE + + + ++ L LH + L ++E + +N+ N +
Sbjct: 543 VHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVS- 601
Query: 233 YSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAIDT 292
Q L + H R+++ ++ I + + + + E+ ++ + +
Sbjct: 602 -IQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSE 660
Query: 293 ISPLNQKFSQYLH----ENASYVRPLEEGMLHLFESITEDTVTVLETTV---KLKTFSEH 345
+ LN+ + EN V E+ L E + + LE LK
Sbjct: 661 LEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGE 720
Query: 346 LTSYICFLRKILPYQLKSLEEECES-----SLCTSALRARNLELSQDMKKMTAVFEKLQT 400
+ + +C+ +K L + E+ E +L TSAL+ + L + +K +L+
Sbjct: 721 IEAELCWAKKRLLEEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKK 780
Query: 401 YIALLALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQ 460
I + E +L SS L + I K + + ++ EL +Q
Sbjct: 781 NIEQMDTDHKETKDVL----SSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQ 836
Query: 461 KLITTNDCILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQY 520
L N+ + ++ G + +N+L + L + P + + + +
Sbjct: 837 AL-RKNEILRQTIEEKDRSLGSMKE-ENNHLQEELERLREEQSRTAPVADPKTLDSVTEL 894
Query: 521 KKKAAAYMKSLRKPLLESVPYEEALANRRILLSSTESREGLAQQVQQSLEKISKLEQEKE 580
+ + + ++++ L E + + +++I+ +S+ L Q +Q+ +++ E +
Sbjct: 895 ASE-VSQLNTIKEHLEEEIKH-----HQKIIEDQNQSKMQLLQSLQEQKKEMD--EFRYQ 946
Query: 581 HWMLEAQLAKIKLEKEN-----QRIADKLKNTGSAQLVGLAQENAAV-----SNTAGQDE 630
H + A ++ LEK+ Q+ +++K + + +N+ + + +
Sbjct: 947 HEQMNATHTQLFLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNIEN 1006
Query: 631 ATAKAVLEPIQSTSLVPDVESREDLIKNHYMARIVELTSQLQLADSKSVHFYA------- 683
+ K L ++ LV ++ RE IK + + LT Q+ V
Sbjct: 1007 GSEKHDLSKAETERLVKGIKERELEIK-LLNEKNISLTKQIDQLSKDEVGKLTQIIQQKD 1065
Query: 684 -ECRALSKRLALAEKSKEALTEEMKLASQNISR-----LQDELTTTKRSYEDQLSMMSDH 737
E +AL R++ +++ + + +L + + R + +E T + + M D
Sbjct: 1066 LEIQALHARISSTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDI 1125
Query: 738 LCSMNETLSKQREE 751
+ + L K ++E
Sbjct: 1126 VAAKEAALIKLQDE 1139
Score = 33.5 bits (75), Expect = 0.76
Identities = 54/229 (23%), Positives = 101/229 (44%), Gaps = 27/229 (11%)
Query: 20 LRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRK--LQQEMDSLTFRNLQLAKRVELLQ 77
LR++N+ LKK D + A + Q+K + S R Q+E++ + Q+A + +LL+
Sbjct: 64 LRSENERLKKLCTDLEEKHEASEIQIKQQSTSYRNQLQQKEVEISHLKARQIALQDQLLK 123
Query: 78 -DELALSEPRGKKNKKSGESSS---QLSQEQKSVFDEDLQ-----KKIEENERL--HIQF 126
A S P G + SSS +S + D+D+ +E RL +
Sbjct: 124 LQSAAQSVPSGAGVPATTASSSFAYGISHHPSAFHDDDMDFGDIISSQQEINRLSNEVSR 183
Query: 127 FEADEQH-KHVEAELRSRLA--TLETEAAQHQAVVDGLTRKYMETIEKLQND-------- 175
E++ H +H+ +++ + ++E + Q ++ L + + I+ Q++
Sbjct: 184 LESEVGHWRHIAQTSKAQGTDNSDQSEICKLQNIIKELKQNRSQEIDDHQHEMSVLQNAH 243
Query: 176 KAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINE 224
+ KL S+ +E + R EE + L + SG +E LS I E
Sbjct: 244 QQKLTEISRRHREELSDYEERIEELE---NLLQQGGSGVIETDLSKIYE 289
Score = 32.3 bits (72), Expect = 1.7
Identities = 35/183 (19%), Positives = 77/183 (42%), Gaps = 21/183 (11%)
Query: 563 QQVQQSLEKISKLEQEKEHWMLEAQLAKIK-LEKENQRIADKLKN------TGSAQLVGL 615
Q++ + ++S+LE E HW AQ +K + + +Q KL+N +Q +
Sbjct: 172 QEINRLSNEVSRLESEVGHWRHIAQTSKAQGTDNSDQSEICKLQNIIKELKQNRSQEIDD 231
Query: 616 AQENAAVSNTAGQDEATAKAVLEPIQSTSLVPDVESREDLIK-------NHYMARIVELT 668
Q +V A Q + T + + + +E E+L++ +++I E+
Sbjct: 232 HQHEMSVLQNAHQQKLTEISRRHREELSDYEERIEELENLLQQGGSGVIETDLSKIYEMQ 291
Query: 669 SQLQL-------ADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDELT 721
+Q+ + K + + ++K+L+ AE ++ L E + + ++ +E
Sbjct: 292 KTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECE 351
Query: 722 TTK 724
K
Sbjct: 352 NLK 354
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.125 0.330
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,726,929
Number of Sequences: 37866
Number of extensions: 959842
Number of successful extensions: 8307
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 167
Number of HSP's successfully gapped in prelim test: 717
Number of HSP's that attempted gapping in prelim test: 5005
Number of HSP's gapped (non-prelim): 3304
length of query: 769
length of database: 18,247,518
effective HSP length: 110
effective length of query: 659
effective length of database: 14,082,258
effective search space: 9280208022
effective search space used: 9280208022
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.