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Search of human proteins with 24308408
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24308408 Cdk5 and Abl enzyme substrate 1 isoform 1 [Homo
sapiens]
(368 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24308408 Cdk5 and Abl enzyme substrate 1 isoform 1 [Homo sapi... 736 0.0
gi|154759423 Cdk5 and Abl enzyme substrate 1 isoform 2 [Homo sap... 700 0.0
gi|145275195 Cdk5 and Abl enzyme substrate 2 [Homo sapiens] 428 e-120
gi|17978469 cyclin T2 isoform b [Homo sapiens] 32 0.69
gi|4502629 cyclin T2 isoform a [Homo sapiens] 32 0.69
gi|170295797 carbamoyl-phosphate synthetase 1 isoform c [Homo sa... 30 2.6
gi|169790915 carbamoyl-phosphate synthetase 1 isoform a precurso... 30 2.6
gi|21361331 carbamoyl-phosphate synthetase 1 isoform b precursor... 30 2.6
gi|61676091 cyclin C isoform a [Homo sapiens] 30 2.6
gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Hom... 30 3.4
gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo ... 30 3.4
gi|195222734 lymphoid enhancer-binding factor 1 isoform 3 [Homo ... 29 5.9
gi|195222732 lymphoid enhancer-binding factor 1 isoform 2 [Homo ... 29 5.9
gi|7705917 lymphoid enhancer-binding factor 1 isoform 1 [Homo sa... 29 5.9
gi|13786123 HMG-box transcription factor TCF-3 [Homo sapiens] 29 5.9
gi|55770834 centromere protein F [Homo sapiens] 29 7.7
>gi|24308408 Cdk5 and Abl enzyme substrate 1 isoform 1 [Homo
sapiens]
Length = 368
Score = 736 bits (1899), Expect = 0.0
Identities = 368/368 (100%), Positives = 368/368 (100%)
Query: 1 MLSKRGCHARIYADFPIRRLISQRSSLETLEDIEENAPLRRCRTLSGSPRPKNFKKIHFI 60
MLSKRGCHARIYADFPIRRLISQRSSLETLEDIEENAPLRRCRTLSGSPRPKNFKKIHFI
Sbjct: 1 MLSKRGCHARIYADFPIRRLISQRSSLETLEDIEENAPLRRCRTLSGSPRPKNFKKIHFI 60
Query: 61 KNMRQHDTRNGRIVLISGRRSFCSIFSVLPYRDSTQVGDLKLDGGRQSTGAVSLKEIIGL 120
KNMRQHDTRNGRIVLISGRRSFCSIFSVLPYRDSTQVGDLKLDGGRQSTGAVSLKEIIGL
Sbjct: 61 KNMRQHDTRNGRIVLISGRRSFCSIFSVLPYRDSTQVGDLKLDGGRQSTGAVSLKEIIGL 120
Query: 121 EGVELGADGKTVSYTQFLLPTNAFGARRNTIDSTSSFSQFRNLSHRSLSIGRASGTQGSL 180
EGVELGADGKTVSYTQFLLPTNAFGARRNTIDSTSSFSQFRNLSHRSLSIGRASGTQGSL
Sbjct: 121 EGVELGADGKTVSYTQFLLPTNAFGARRNTIDSTSSFSQFRNLSHRSLSIGRASGTQGSL 180
Query: 181 DTGSDLGDFMDYDPNLLDDPQWPCGKHKRVLIFPSYMTTVIDYVKPSDLKKDMNETFKEK 240
DTGSDLGDFMDYDPNLLDDPQWPCGKHKRVLIFPSYMTTVIDYVKPSDLKKDMNETFKEK
Sbjct: 181 DTGSDLGDFMDYDPNLLDDPQWPCGKHKRVLIFPSYMTTVIDYVKPSDLKKDMNETFKEK 240
Query: 241 FPHIKLTLSKIRSLKREMRKLAQEDCGLEEPTVAMAFVYFEKLALKGKLNKQNRKLCAGA 300
FPHIKLTLSKIRSLKREMRKLAQEDCGLEEPTVAMAFVYFEKLALKGKLNKQNRKLCAGA
Sbjct: 241 FPHIKLTLSKIRSLKREMRKLAQEDCGLEEPTVAMAFVYFEKLALKGKLNKQNRKLCAGA 300
Query: 301 CVLLAAKIGSDLKKHEVKHLIDKLEEKFRLNRRELIAFEFPVLVALEFALHLPEHEVMPH 360
CVLLAAKIGSDLKKHEVKHLIDKLEEKFRLNRRELIAFEFPVLVALEFALHLPEHEVMPH
Sbjct: 301 CVLLAAKIGSDLKKHEVKHLIDKLEEKFRLNRRELIAFEFPVLVALEFALHLPEHEVMPH 360
Query: 361 YRRLVQSS 368
YRRLVQSS
Sbjct: 361 YRRLVQSS 368
>gi|154759423 Cdk5 and Abl enzyme substrate 1 isoform 2 [Homo
sapiens]
Length = 633
Score = 700 bits (1806), Expect = 0.0
Identities = 351/351 (100%), Positives = 351/351 (100%)
Query: 18 RRLISQRSSLETLEDIEENAPLRRCRTLSGSPRPKNFKKIHFIKNMRQHDTRNGRIVLIS 77
RRLISQRSSLETLEDIEENAPLRRCRTLSGSPRPKNFKKIHFIKNMRQHDTRNGRIVLIS
Sbjct: 283 RRLISQRSSLETLEDIEENAPLRRCRTLSGSPRPKNFKKIHFIKNMRQHDTRNGRIVLIS 342
Query: 78 GRRSFCSIFSVLPYRDSTQVGDLKLDGGRQSTGAVSLKEIIGLEGVELGADGKTVSYTQF 137
GRRSFCSIFSVLPYRDSTQVGDLKLDGGRQSTGAVSLKEIIGLEGVELGADGKTVSYTQF
Sbjct: 343 GRRSFCSIFSVLPYRDSTQVGDLKLDGGRQSTGAVSLKEIIGLEGVELGADGKTVSYTQF 402
Query: 138 LLPTNAFGARRNTIDSTSSFSQFRNLSHRSLSIGRASGTQGSLDTGSDLGDFMDYDPNLL 197
LLPTNAFGARRNTIDSTSSFSQFRNLSHRSLSIGRASGTQGSLDTGSDLGDFMDYDPNLL
Sbjct: 403 LLPTNAFGARRNTIDSTSSFSQFRNLSHRSLSIGRASGTQGSLDTGSDLGDFMDYDPNLL 462
Query: 198 DDPQWPCGKHKRVLIFPSYMTTVIDYVKPSDLKKDMNETFKEKFPHIKLTLSKIRSLKRE 257
DDPQWPCGKHKRVLIFPSYMTTVIDYVKPSDLKKDMNETFKEKFPHIKLTLSKIRSLKRE
Sbjct: 463 DDPQWPCGKHKRVLIFPSYMTTVIDYVKPSDLKKDMNETFKEKFPHIKLTLSKIRSLKRE 522
Query: 258 MRKLAQEDCGLEEPTVAMAFVYFEKLALKGKLNKQNRKLCAGACVLLAAKIGSDLKKHEV 317
MRKLAQEDCGLEEPTVAMAFVYFEKLALKGKLNKQNRKLCAGACVLLAAKIGSDLKKHEV
Sbjct: 523 MRKLAQEDCGLEEPTVAMAFVYFEKLALKGKLNKQNRKLCAGACVLLAAKIGSDLKKHEV 582
Query: 318 KHLIDKLEEKFRLNRRELIAFEFPVLVALEFALHLPEHEVMPHYRRLVQSS 368
KHLIDKLEEKFRLNRRELIAFEFPVLVALEFALHLPEHEVMPHYRRLVQSS
Sbjct: 583 KHLIDKLEEKFRLNRRELIAFEFPVLVALEFALHLPEHEVMPHYRRLVQSS 633
>gi|145275195 Cdk5 and Abl enzyme substrate 2 [Homo sapiens]
Length = 478
Score = 428 bits (1101), Expect = e-120
Identities = 228/358 (63%), Positives = 268/358 (74%), Gaps = 12/358 (3%)
Query: 18 RRLISQRSSLETLEDIEENAPLRRCRTLSGSPRPKNFKKIHFIKNMRQHDTRNGRIVLIS 77
+R+ SQR SLE LED AP +R + SGSPR K KK HFIKNMRQ+DTRN RIVLI
Sbjct: 122 KRVTSQRCSLEFLEDAVGCAPAQRTKHTSGSPRHKGLKKTHFIKNMRQYDTRNSRIVLIC 181
Query: 78 GRRSFCSIFSVLPYRDSTQVGDLKLDGGRQS--TGAVSLKE--IIGLEGVELGADGKTVS 133
+RS C+ FSVLPY + ++ DL++D +Q +G VS+ + LEGVELGADGK VS
Sbjct: 182 AKRSLCAAFSVLPYGEGLRISDLRVDSQKQRHPSGGVSVSSEMVFELEGVELGADGKVVS 241
Query: 134 YTQFLLPTNAFGARRNTIDSTSSFSQFRNLSHRSLSIGR-----ASGTQGSLDTGSDLGD 188
Y +FL PTNA ++ DS R R+L R S + GSD+GD
Sbjct: 242 YAKFLYPTNALVTHKS--DSHGLLPTPRPSVPRTLPGSRHKPAPTKSAPASTELGSDVGD 299
Query: 189 FMDYDPNLLDDPQWPCGKHKRVLIFPSYMTTVIDYVKPSDLKKDMNETFKEKFPHIKLTL 248
++Y+PNLLDDPQWPCGKHKRVLIF SYMTTVI+YVKPSDLKKDMNETF+EKFPH+KLTL
Sbjct: 300 TLEYNPNLLDDPQWPCGKHKRVLIFASYMTTVIEYVKPSDLKKDMNETFREKFPHVKLTL 359
Query: 249 SKIRSLKREMRKLAQEDCGLEEPTVAMAFVYFEKLALKGKLNKQNRKLCAGACVLLAAKI 308
SKIRSLKREMR L++E C LE TVAMA+VYFEKL L+GKL+KQNRKLCAGACVLLAAKI
Sbjct: 360 SKIRSLKREMRSLSEE-CSLEPVTVAMAYVYFEKLVLQGKLSKQNRKLCAGACVLLAAKI 418
Query: 309 GSDLKKHEVKHLIDKLEEKFRLNRRELIAFEFPVLVALEFALHLPEHEVMPHYRRLVQ 366
SDL+K V LIDKLEE+FR NRR+LI FEF VLVALE AL+LPE++V+PHYRRL Q
Sbjct: 419 SSDLRKSGVTQLIDKLEERFRFNRRDLIGFEFTVLVALELALYLPENQVLPHYRRLTQ 476
>gi|17978469 cyclin T2 isoform b [Homo sapiens]
Length = 730
Score = 32.3 bits (72), Expect = 0.69
Identities = 28/123 (22%), Positives = 52/123 (42%), Gaps = 19/123 (15%)
Query: 253 SLKREMRKLAQE---DCGLEEPTVAMAFVYFEKLALKGKLNKQNRKLCAGACVLLAAKIG 309
S +++ L QE + + T+ A VY + + K N+ + + + LAAK+
Sbjct: 35 SCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVE 94
Query: 310 SDLKK------------HEVKHLIDKLEEKFRLNRRELIAFEFPVLVALEFALHLPEHEV 357
+K H ++ L+D + + +EL+ E +L L F + + EH
Sbjct: 95 EQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQTQELVILETIMLQTLGFEITI-EH-- 151
Query: 358 MPH 360
PH
Sbjct: 152 -PH 153
>gi|4502629 cyclin T2 isoform a [Homo sapiens]
Length = 663
Score = 32.3 bits (72), Expect = 0.69
Identities = 28/123 (22%), Positives = 52/123 (42%), Gaps = 19/123 (15%)
Query: 253 SLKREMRKLAQE---DCGLEEPTVAMAFVYFEKLALKGKLNKQNRKLCAGACVLLAAKIG 309
S +++ L QE + + T+ A VY + + K N+ + + + LAAK+
Sbjct: 35 SCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVE 94
Query: 310 SDLKK------------HEVKHLIDKLEEKFRLNRRELIAFEFPVLVALEFALHLPEHEV 357
+K H ++ L+D + + +EL+ E +L L F + + EH
Sbjct: 95 EQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQTQELVILETIMLQTLGFEITI-EH-- 151
Query: 358 MPH 360
PH
Sbjct: 152 -PH 153
>gi|170295797 carbamoyl-phosphate synthetase 1 isoform c [Homo
sapiens]
Length = 1049
Score = 30.4 bits (67), Expect = 2.6
Identities = 20/70 (28%), Positives = 40/70 (57%), Gaps = 7/70 (10%)
Query: 248 LSKIRSLKREMRKLAQEDCGLEEPTVAMAF-----VYFEKLALKGKLNKQNRKLCAGACV 302
+S IR+L++ +K +C E TV+ F +YFE+L+L+ L+ +++ C G +
Sbjct: 546 VSSIRTLRQLGKKTVVVNCNPE--TVSTDFDECDKLYFEELSLERILDIYHQEACGGCII 603
Query: 303 LLAAKIGSDL 312
+ +I ++L
Sbjct: 604 SVGGQIPNNL 613
>gi|169790915 carbamoyl-phosphate synthetase 1 isoform a precursor
[Homo sapiens]
Length = 1506
Score = 30.4 bits (67), Expect = 2.6
Identities = 20/70 (28%), Positives = 40/70 (57%), Gaps = 7/70 (10%)
Query: 248 LSKIRSLKREMRKLAQEDCGLEEPTVAMAF-----VYFEKLALKGKLNKQNRKLCAGACV 302
+S IR+L++ +K +C E TV+ F +YFE+L+L+ L+ +++ C G +
Sbjct: 1003 VSSIRTLRQLGKKTVVVNCNPE--TVSTDFDECDKLYFEELSLERILDIYHQEACGGCII 1060
Query: 303 LLAAKIGSDL 312
+ +I ++L
Sbjct: 1061 SVGGQIPNNL 1070
>gi|21361331 carbamoyl-phosphate synthetase 1 isoform b precursor
[Homo sapiens]
Length = 1500
Score = 30.4 bits (67), Expect = 2.6
Identities = 20/70 (28%), Positives = 40/70 (57%), Gaps = 7/70 (10%)
Query: 248 LSKIRSLKREMRKLAQEDCGLEEPTVAMAF-----VYFEKLALKGKLNKQNRKLCAGACV 302
+S IR+L++ +K +C E TV+ F +YFE+L+L+ L+ +++ C G +
Sbjct: 997 VSSIRTLRQLGKKTVVVNCNPE--TVSTDFDECDKLYFEELSLERILDIYHQEACGGCII 1054
Query: 303 LLAAKIGSDL 312
+ +I ++L
Sbjct: 1055 SVGGQIPNNL 1064
>gi|61676091 cyclin C isoform a [Homo sapiens]
Length = 283
Score = 30.4 bits (67), Expect = 2.6
Identities = 20/79 (25%), Positives = 38/79 (48%), Gaps = 7/79 (8%)
Query: 230 KKDMNETFKEKFPHIKLTLSKIRSLKREMRKLAQEDCGLEEPTVAMAFVYFEKLALKGKL 289
+KD+ +E++ +++ + + E KL Q+ +A A VYF++ + L
Sbjct: 26 QKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQ-------VIATATVYFKRFYARYSL 78
Query: 290 NKQNRKLCAGACVLLAAKI 308
+ L A CV LA+K+
Sbjct: 79 KSIDPVLMAPTCVFLASKV 97
>gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Homo
sapiens]
Length = 1134
Score = 30.0 bits (66), Expect = 3.4
Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 4/70 (5%)
Query: 231 KDMNETFKEKFPHIKLTLSKIRSLKREMRKLAQ---EDCGLEEPTVAMAFVYFEKLALKG 287
+ MN F++K + L +SK+ L R++ L + + VA +++L L+
Sbjct: 221 EQMNNLFQQKQRELVLAVSKVEELTRQLEMLKNGRIDSHHDNQSAVAELDRLYKELQLRN 280
Query: 288 KLN-KQNRKL 296
KLN +QN KL
Sbjct: 281 KLNQEQNAKL 290
>gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo
sapiens]
Length = 1005
Score = 30.0 bits (66), Expect = 3.4
Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 4/70 (5%)
Query: 231 KDMNETFKEKFPHIKLTLSKIRSLKREMRKLAQ---EDCGLEEPTVAMAFVYFEKLALKG 287
+ MN F++K + L +SK+ L R++ L + + VA +++L L+
Sbjct: 92 EQMNNLFQQKQRELVLAVSKVEELTRQLEMLKNGRIDSHHDNQSAVAELDRLYKELQLRN 151
Query: 288 KLN-KQNRKL 296
KLN +QN KL
Sbjct: 152 KLNQEQNAKL 161
>gi|195222734 lymphoid enhancer-binding factor 1 isoform 3 [Homo
sapiens]
Length = 386
Score = 29.3 bits (64), Expect = 5.9
Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 8/76 (10%)
Query: 203 PCGKHKRVLIFPSYMTTVIDYVKP---SDLK--KDMNETFKE---KFPHIKLTLSKIRSL 254
P G H + P+ +T + P SDL K +E KE K PHIK L+
Sbjct: 222 PPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLY 281
Query: 255 KREMRKLAQEDCGLEE 270
+EMR +C L+E
Sbjct: 282 MKEMRANVVAECTLKE 297
>gi|195222732 lymphoid enhancer-binding factor 1 isoform 2 [Homo
sapiens]
Length = 371
Score = 29.3 bits (64), Expect = 5.9
Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 8/76 (10%)
Query: 203 PCGKHKRVLIFPSYMTTVIDYVKP---SDLK--KDMNETFKE---KFPHIKLTLSKIRSL 254
P G H + P+ +T + P SDL K +E KE K PHIK L+
Sbjct: 222 PPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLY 281
Query: 255 KREMRKLAQEDCGLEE 270
+EMR +C L+E
Sbjct: 282 MKEMRANVVAECTLKE 297
>gi|7705917 lymphoid enhancer-binding factor 1 isoform 1 [Homo
sapiens]
Length = 399
Score = 29.3 bits (64), Expect = 5.9
Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 8/76 (10%)
Query: 203 PCGKHKRVLIFPSYMTTVIDYVKP---SDLK--KDMNETFKE---KFPHIKLTLSKIRSL 254
P G H + P+ +T + P SDL K +E KE K PHIK L+
Sbjct: 250 PPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLY 309
Query: 255 KREMRKLAQEDCGLEE 270
+EMR +C L+E
Sbjct: 310 MKEMRANVVAECTLKE 325
>gi|13786123 HMG-box transcription factor TCF-3 [Homo sapiens]
Length = 588
Score = 29.3 bits (64), Expect = 5.9
Identities = 16/57 (28%), Positives = 27/57 (47%), Gaps = 5/57 (8%)
Query: 214 PSYMTTVIDYVKPSDLKKDMNETFKEKFPHIKLTLSKIRSLKREMRKLAQEDCGLEE 270
P ++ + P +KK+ +EK PH+K L+ +EMR +C L+E
Sbjct: 321 PPSLSPAVSVKSPVTVKKE-----EEKKPHVKKPLNAFMLYMKEMRAKVVAECTLKE 372
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 28.9 bits (63), Expect = 7.7
Identities = 32/123 (26%), Positives = 56/123 (45%), Gaps = 12/123 (9%)
Query: 233 MNETFKEKFPHIKLTLSKIRSLKREMRKLAQEDCGLEEPTVAMAFVYFEKLAL-KGKLNK 291
+N+++KE+F ++ LS+IRS E + E LE + V EKL L K NK
Sbjct: 1889 VNDSWKERFLDVENELSRIRS---EKASIEHEALYLE---ADLEVVQTEKLCLEKDNENK 1942
Query: 292 QNRKLCAGACVLLAAKIGSDLK-----KHEVKHLIDKLEEKFRLNRRELIAFEFPVLVAL 346
Q +C + + + L+ + +D+L EK + +EL + + L +
Sbjct: 1943 QKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCI 2002
Query: 347 EFA 349
+ A
Sbjct: 2003 QVA 2005
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,981,523
Number of Sequences: 37866
Number of extensions: 556164
Number of successful extensions: 1383
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1375
Number of HSP's gapped (non-prelim): 17
length of query: 368
length of database: 18,247,518
effective HSP length: 104
effective length of query: 264
effective length of database: 14,309,454
effective search space: 3777695856
effective search space used: 3777695856
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.