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Search of human proteins with 24308303
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24308303 SH3-binding domain protein 5-like [Homo sapiens]
(393 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24308303 SH3-binding domain protein 5-like [Homo sapiens] 774 0.0
gi|109134336 SH3-domain binding protein 5 (BTK-associated) isofo... 211 7e-55
gi|109134344 SH3-domain binding protein 5 (BTK-associated) isofo... 104 2e-22
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 50 3e-06
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 49 6e-06
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 49 6e-06
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 49 6e-06
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 49 6e-06
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 49 6e-06
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 49 6e-06
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 49 6e-06
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 49 6e-06
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 49 8e-06
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 48 1e-05
gi|221139761 zinc finger protein 853 [Homo sapiens] 47 2e-05
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 47 2e-05
gi|62243374 MAD1-like 1 protein [Homo sapiens] 47 2e-05
gi|62243369 MAD1-like 1 protein [Homo sapiens] 47 2e-05
gi|62243332 MAD1-like 1 protein [Homo sapiens] 47 2e-05
gi|156104908 myosin heavy chain 6 [Homo sapiens] 47 2e-05
gi|148806928 hypothetical protein LOC57482 [Homo sapiens] 47 3e-05
gi|239756174 PREDICTED: hypothetical protein [Homo sapiens] 46 5e-05
gi|239750672 PREDICTED: hypothetical protein [Homo sapiens] 46 5e-05
gi|239744982 PREDICTED: hypothetical protein [Homo sapiens] 46 5e-05
gi|21735548 centrosomal protein 2 [Homo sapiens] 45 9e-05
gi|59806361 hypothetical protein LOC387104 [Homo sapiens] 45 1e-04
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 45 1e-04
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 44 2e-04
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 44 2e-04
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 44 2e-04
>gi|24308303 SH3-binding domain protein 5-like [Homo sapiens]
Length = 393
Score = 774 bits (1999), Expect = 0.0
Identities = 393/393 (100%), Positives = 393/393 (100%)
Query: 1 MAELRQVPGGRETPQGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKLSPREEEELDPRI 60
MAELRQVPGGRETPQGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKLSPREEEELDPRI
Sbjct: 1 MAELRQVPGGRETPQGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKLSPREEEELDPRI 60
Query: 61 QEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEAR 120
QEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEAR
Sbjct: 61 QEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEAR 120
Query: 121 RLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKV 180
RLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKV
Sbjct: 121 RLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKV 180
Query: 181 NEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHK 240
NEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHK
Sbjct: 181 NEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHK 240
Query: 241 AKVTELEQQVAQAKTRYSVALRNLEQISEQIHARRRGGLPPHPLGPRRSSPVGAEAGPED 300
AKVTELEQQVAQAKTRYSVALRNLEQISEQIHARRRGGLPPHPLGPRRSSPVGAEAGPED
Sbjct: 241 AKVTELEQQVAQAKTRYSVALRNLEQISEQIHARRRGGLPPHPLGPRRSSPVGAEAGPED 300
Query: 301 MEDGDSGIEGAEGAGLEEGSSLGPGPAPDTDTLSLLSLRTVASDLQKCDSVEHLRGLSDH 360
MEDGDSGIEGAEGAGLEEGSSLGPGPAPDTDTLSLLSLRTVASDLQKCDSVEHLRGLSDH
Sbjct: 301 MEDGDSGIEGAEGAGLEEGSSLGPGPAPDTDTLSLLSLRTVASDLQKCDSVEHLRGLSDH 360
Query: 361 VSLDGQELGTRSGGRRGSDGGARGGRHQRSVSL 393
VSLDGQELGTRSGGRRGSDGGARGGRHQRSVSL
Sbjct: 361 VSLDGQELGTRSGGRRGSDGGARGGRHQRSVSL 393
>gi|109134336 SH3-domain binding protein 5 (BTK-associated) isoform
a [Homo sapiens]
Length = 455
Score = 211 bits (538), Expect = 7e-55
Identities = 120/287 (41%), Positives = 175/287 (60%), Gaps = 25/287 (8%)
Query: 52 EEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIE 111
EEEE+DPRIQ ELE LNQ++++IN+ E +L++AR +R +L E+ KL+ +G +E
Sbjct: 37 EEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATVKLDELVKKIGKAVE 96
Query: 112 KARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMAD-KNRLDPTWQ 170
++PY+EARR+A++AQ E QKA ++RA + AA+E + +AEQ ++ D K + D WQ
Sbjct: 97 DSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQ 156
Query: 171 EMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKA 230
EMLNHAT +V EAE+ + R E H+ A R++ L+K L+RAI KS+PYFELKA
Sbjct: 157 EMLNHATQRVMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKA 216
Query: 231 QFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQIHARRRGGLPPHPLGPRRSS 290
++ LE+ K V +L+ ++ AK Y +AL+NLE IS++IH RRR +GP R
Sbjct: 217 KYYVQLEQLKKTVDDLQAKLTLAKGEYKMALKNLEMISDEIHERRRSS----AMGP-RGC 271
Query: 291 PVGAEAGPEDMEDGDSGIEGAEGAGLEEGSSLGPGPAPDTDTLSLLS 337
VGAE +ED PG P+ D +S+ S
Sbjct: 272 GVGAEGSSTSVED-------------------LPGSKPEPDAISVAS 299
Score = 35.0 bits (79), Expect = 0.12
Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 8/91 (8%)
Query: 155 EQGVMADKNRLDPTWQ---EMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQAL 211
EQG + ++ +DP Q E LN +T +N E E E Q+ + +A ++ L
Sbjct: 32 EQG-LEEEEEVDPRIQGELEKLNQSTDDINRRETEL---EDARQKFRSVLVEATVKLDEL 87
Query: 212 QKTLRRAIGKSRPYFELKAQFSQI-LEEHKA 241
K + +A+ S+PY+E + Q LE KA
Sbjct: 88 VKKIGKAVEDSKPYWEARRVARQAQLEAQKA 118
>gi|109134344 SH3-domain binding protein 5 (BTK-associated) isoform
b [Homo sapiens]
Length = 298
Score = 104 bits (259), Expect = 2e-22
Identities = 65/166 (39%), Positives = 90/166 (54%), Gaps = 24/166 (14%)
Query: 172 MLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQ 231
MLNHAT +V EAE+ + R E H+ A R++ L+K L+RAI KS+PYFELKA+
Sbjct: 1 MLNHATQRVMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAK 60
Query: 232 FSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQIHARRRGGLPPHPLGPRRSSP 291
+ LE+ K V +L+ ++ AK Y +AL+NLE IS++IH RRR +GP R
Sbjct: 61 YYVQLEQLKKTVDDLQAKLTLAKGEYKMALKNLEMISDEIHERRRSS----AMGP-RGCG 115
Query: 292 VGAEAGPEDMEDGDSGIEGAEGAGLEEGSSLGPGPAPDTDTLSLLS 337
VGAE +ED PG P+ D +S+ S
Sbjct: 116 VGAEGSSTSVED-------------------LPGSKPEPDAISVAS 142
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 50.4 bits (119), Expect = 3e-06
Identities = 61/282 (21%), Positives = 123/282 (43%), Gaps = 28/282 (9%)
Query: 3 ELRQVPGGRETPQGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKLSPREEEELDPRIQE 62
++ Q+ + + +L+ + E R A++ +++ E + S RE + ++ E
Sbjct: 552 QVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLA---TAAEEREASLRERDAALKQL-E 607
Query: 63 ELEHLNQASEEINQVELQL-----DEARTTYRRILQESARKLNTQGSHLGSCIEKARPYY 117
LE A EI Q +LQ+ D A+T+ + +E A +L+ + L +C+E AR
Sbjct: 608 ALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKA-ELSRKVEELQACVETARQ-- 664
Query: 118 EARRLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHAT 177
++ + + Q A L + A + + V +K++L Q +
Sbjct: 665 ------EQHEAQAQVAELELQLRSEQQKATEK------ERVAQEKDQLQEQLQALKESLK 712
Query: 178 CKVNEAEEERLRGEREHQRVTRLCQQAEARVQAL---QKTLRRAIGKSRPYFE-LKAQFS 233
EEE+ R + R + +A ++L K R+ + + R + L+A+
Sbjct: 713 VTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQ 772
Query: 234 QILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQIHARR 275
Q+ E H+A+ L +++A+A A EQ+ +++ A R
Sbjct: 773 QLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWR 814
Score = 35.4 bits (80), Expect = 0.090
Identities = 50/264 (18%), Positives = 107/264 (40%), Gaps = 27/264 (10%)
Query: 29 RSPVAEEPGGGGSSSSEAKLSPREEEELDP---RIQEELEHLNQASEEINQVELQLDEAR 85
R + + G +E + RE EL P ++ E+ Q E QL +
Sbjct: 1382 REELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLK 1441
Query: 86 TTYRRILQES---ARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVS 142
+ + +E+ + N L +++AR Y A A ET+ A ++ E
Sbjct: 1442 KAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREA--- 1498
Query: 143 MHNAAREMVFV------AEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQR 196
+ ARE+ + A+ V+ ++ R +QE T +V + E + ++ +
Sbjct: 1499 -QSTARELEVMTAKYEGAKVKVLEERQR----FQEERQKLTAQVEQLEVFQREQTKQVEE 1553
Query: 197 VTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQ-------Q 249
+++ ++ + Q+ L+ + + + L E +A++++ EQ Q
Sbjct: 1554 LSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQ 1613
Query: 250 VAQAKTRYSVALRNLEQISEQIHA 273
+ +AKT Y + +++ EQ+ +
Sbjct: 1614 MEKAKTHYDAKKQQNQELQEQLRS 1637
Score = 30.4 bits (67), Expect = 2.9
Identities = 58/291 (19%), Positives = 110/291 (37%), Gaps = 43/291 (14%)
Query: 1 MAELRQVPGGRETPQGELRPEV--VEDEVPRSPVAEEPGGGGSSSSEAKLSP-------- 50
+A+LR + + ELR V +++++ + G G S + + P
Sbjct: 1066 LAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEAL 1125
Query: 51 REE----EELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHL 106
R E E+ + QE+ + L ++ E + D A T + L+E A++L S L
Sbjct: 1126 RAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSAL 1185
Query: 107 GSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLD 166
S + + + Q+ KA ++ V+ E KN L
Sbjct: 1186 ASAQRELAAF-------RTKVQDHSKAEDEWKAQVARGRQEAER-----------KNSLI 1227
Query: 167 PTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYF 226
+ +E +V+ + L E E + + RL + Q L++ LR ++
Sbjct: 1228 SSLEE-------EVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNS 1280
Query: 227 ELKAQFSQILEEHKAKVTE--LEQQVAQAKTRYSVA--LRNLEQISEQIHA 273
A+ S L E + E +Q+VA R + E++ +++ A
Sbjct: 1281 ARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKA 1331
Score = 30.0 bits (66), Expect = 3.8
Identities = 24/92 (26%), Positives = 45/92 (48%), Gaps = 4/92 (4%)
Query: 49 SPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGS 108
S +E + L ++ E L+Q + +LQ+++A+T Y Q++ ++L Q L S
Sbjct: 1582 SQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQN-QELQEQ---LRS 1637
Query: 109 CIEKARPYYEARRLAKEAQQETQKAALRYERA 140
+ + E R A+ E Q+A L+ + A
Sbjct: 1638 LEQLQKENKELRAEAERLGHELQQAGLKTKEA 1669
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 49.3 bits (116), Expect = 6e-06
Identities = 57/233 (24%), Positives = 99/233 (42%), Gaps = 25/233 (10%)
Query: 51 REEEELDPRIQEELEHLNQAS-------EEINQVELQLDEARTTYRRILQESARKLN--T 101
R E + R+Q+ L +A+ EE+ +++ +++EAR R QESAR+L
Sbjct: 1981 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2040
Query: 102 QGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQG-VMA 160
+ + E+ + ++ +E QQ Q+ ++ AAR AE+ V A
Sbjct: 2041 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2100
Query: 161 DKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEA---RVQALQKTLRR 217
++ A + E ERL+ E Q R QA A R +A Q+ RR
Sbjct: 2101 EREA-----------AQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARR 2149
Query: 218 AIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQ 270
A + + +A ++ +E+HK + +Q AQ + + LE+ Q
Sbjct: 2150 AQAEQAALRQKQAADAE-MEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQ 2201
Score = 48.5 bits (114), Expect = 1e-05
Identities = 57/277 (20%), Positives = 114/277 (41%), Gaps = 21/277 (7%)
Query: 41 SSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLN 100
+ + KL E R +E+ + + +EEI + +L E T + L ++
Sbjct: 2380 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGE-KLHRTELATQEKVTLVQTLEIQR 2438
Query: 101 TQGSHLGSCI---------EKARPYYEAR--RLAKEAQQETQKAALRYERAVSMHN--AA 147
Q H + EK + EA+ +L E Q Q+ L E + +
Sbjct: 2439 QQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSE 2498
Query: 148 REMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEAR 207
++ + E+ + +K +L+ +Q+ + A E + ++ + E+E QR+ ++A R
Sbjct: 2499 KDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRR 2558
Query: 208 VQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQI 267
++ +RR + + + + Q ++L E + L +Q+ + ++ AL +
Sbjct: 2559 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR---LREQLQLLEEQHRAALAH---- 2611
Query: 268 SEQIHARRRGGLPPHPLGPRRSSPVGAEAGPEDMEDG 304
SE++ A + P G AEA PE DG
Sbjct: 2612 SEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDG 2648
Score = 45.4 bits (106), Expect = 9e-05
Identities = 59/246 (23%), Positives = 98/246 (39%), Gaps = 43/246 (17%)
Query: 51 REEEELDPR-----IQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQ--- 102
REE +D + IQEEL+ L Q+SE Q + + EA R ++E R + Q
Sbjct: 1404 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1463
Query: 103 -----GSHLGSC-----------IEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNA 146
G G +K + EA RL ++ Q E+Q+ +R + A
Sbjct: 1464 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQR-----KRQAEVELA 1518
Query: 147 AREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEA 206
+R AE +K R +E+ A E E RLR Q +Q +
Sbjct: 1519 SR---VKAEAEAAREKQRALQALEELRLQA-----EEAERRLR-----QAEVERARQVQV 1565
Query: 207 RVQALQKTLRRAIGKSRPYF-ELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLE 265
++ Q++ + R F E AQ + L+E V +L ++ + + + A R E
Sbjct: 1566 ALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERARE 1625
Query: 266 QISEQI 271
+ ++
Sbjct: 1626 EAEREL 1631
Score = 43.9 bits (102), Expect = 3e-04
Identities = 65/254 (25%), Positives = 107/254 (42%), Gaps = 41/254 (16%)
Query: 33 AEEPGGGGSSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRR-I 91
AE + EA++ E R EE E L Q++EE Q Q A R+
Sbjct: 2083 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2142
Query: 92 LQESARKLNTQGSHL------GSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHN 145
QE+AR+ + + L + +EK + + E + L ++AQ E + LR + + H
Sbjct: 2143 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAE-QTLRQKAQVEQELTTLRLQLEETDH- 2200
Query: 146 AAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAE 205
KN LD Q + AT EA +R + E E V R+ +
Sbjct: 2201 ---------------QKNLLDEELQRLKAEAT----EAARQRSQVEEELFSV-RVQMEEL 2240
Query: 206 ARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALR--- 262
++++A + RA+ K + L+E K+ +QVA+ R SVA +
Sbjct: 2241 SKLKARIEAENRAL-----ILRDKDNTQRFLQEEAEKM----KQVAEEAARLSVAAQEAA 2291
Query: 263 NLEQISEQIHARRR 276
L Q++E+ A++R
Sbjct: 2292 RLRQLAEEDLAQQR 2305
Score = 43.9 bits (102), Expect = 3e-04
Identities = 61/260 (23%), Positives = 110/260 (42%), Gaps = 37/260 (14%)
Query: 18 LRPEVVEDEVPRSPVAEEPGGGGSSSSEA--KLSPREEEELDPRIQ-EELEHLNQASEEI 74
LR ++ E + ++ + EE + ++EA + S EEE R+Q EEL L E
Sbjct: 2191 LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2250
Query: 75 NQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKE--AQQETQK 132
N+ + D+ T +R LQE A K+ A+ R+LA+E AQQ
Sbjct: 2251 NRALILRDKDNT--QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALA 2308
Query: 133 AALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGER 192
+ E+ ++ A R AE ++ + L + + RL+ ++
Sbjct: 2309 EKMLKEKMQAVQEATR---LKAEAELLQQQKELA---------------QEQARRLQEDK 2350
Query: 193 EHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQ 252
E ++ QQ Q Q+TL + + E+ A+ ++ K +V E+ + A+
Sbjct: 2351 E-----QMAQQLAEETQGFQRTLE---AERQRQLEMSAEAERL----KLRVAEMSRAQAR 2398
Query: 253 AKTRYSVALRNLEQISEQIH 272
A+ + E+I E++H
Sbjct: 2399 AEEDAQRFRKQAEEIGEKLH 2418
Score = 42.7 bits (99), Expect = 6e-04
Identities = 66/289 (22%), Positives = 103/289 (35%), Gaps = 51/289 (17%)
Query: 15 QGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKL------SPREEEELDPRIQEELEHLN 68
+ E + EDE + EE + E +L S E E +++ L
Sbjct: 1862 ENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR 1921
Query: 69 QASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSC----IEKARPYY---EARR 121
Q EEI ++ ++A + E R + L S +E AR E R
Sbjct: 1922 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 1981
Query: 122 LAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVN 181
+EA++ QK+ E A AA E V KV
Sbjct: 1982 RRREAEERVQKSLAAEEEAARQRKAALEEV----------------------ERLKAKVE 2019
Query: 182 EAEEERLRGEREHQRVTRLCQQ-AEARVQALQKTLRRAIGKSRPYFELKAQFSQIL---- 236
EA R R E+E R +L Q+ A+ R+QA +K A+ + + Q Q +
Sbjct: 2020 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2079
Query: 237 -----------EEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQIHAR 274
EE + + E++ AQ++ + A R + EQ AR
Sbjct: 2080 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQAR 2128
Score = 42.4 bits (98), Expect = 7e-04
Identities = 57/270 (21%), Positives = 104/270 (38%), Gaps = 44/270 (16%)
Query: 45 EAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQG- 103
+A+L P P++Q E + Q ++ +L + Y + + E+ R++ +
Sbjct: 1290 KAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEER 1349
Query: 104 -------------SHLGSCIEKARPYYE--------ARRLAKEAQQETQKAALRYERAV- 141
+ + + +EK R E A R AKE QQ Q+ +R E A
Sbjct: 1350 LAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAV 1409
Query: 142 ---------------SMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEE 186
++ E+ A Q A+++RL +E + ++ E +
Sbjct: 1410 DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRL--RIEEEIRVVRLQLEATERQ 1467
Query: 187 RLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTEL 246
R E E Q + ++AEA+ + Q+ R R + ++Q + E A +
Sbjct: 1468 RGGAEGELQALRARAEEAEAQKRQAQEEAERL----RRQVQDESQRKRQAEVELASRVKA 1523
Query: 247 EQQVAQAKTRYSVALRNLEQISEQIHARRR 276
E + A+ K R AL L +E+ R R
Sbjct: 1524 EAEAAREKQRALQALEELRLQAEEAERRLR 1553
Score = 38.5 bits (88), Expect = 0.011
Identities = 65/271 (23%), Positives = 108/271 (39%), Gaps = 33/271 (12%)
Query: 34 EEPGGGGSSSSEAKLSPREEEELDPR-IQEELEHLNQ----ASEEINQVELQL------- 81
E GG +A + EE E R QEE E L + S+ Q E++L
Sbjct: 1465 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1524
Query: 82 DEARTTYRRILQESARKLNTQGSHL-----GSCIEKARPYYEARRLAK---EAQQETQKA 133
EA +R LQ + +L Q + +E+AR A A+ EA+ ++++A
Sbjct: 1525 AEAAREKQRALQ-ALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRA 1583
Query: 134 ALRYERAVSMHNAAREMVFVAE--------QGVMADKNRLDPTWQEMLNHATCKVNEAEE 185
+ + A + E V VA+ A+ R + L K NEA
Sbjct: 1584 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1643
Query: 186 ERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTE 245
RL+ E Q+ + +AE + + ++ RR GK+ E + ++ E+ K +
Sbjct: 1644 LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR-GKAE---EQAVRQRELAEQELEKQRQ 1699
Query: 246 LEQQVAQAKTRYSVALRNLEQISEQIHARRR 276
L + AQ + L L +EQ +R+
Sbjct: 1700 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1730
Score = 36.6 bits (83), Expect = 0.040
Identities = 59/266 (22%), Positives = 106/266 (39%), Gaps = 39/266 (14%)
Query: 5 RQVPGGRETPQGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKLSPREEEELDPRIQEEL 64
RQV ET Q E+ + R+ AE+ +++ + S +EE +++EE
Sbjct: 1561 RQVQVALETAQRSAEAEL---QSKRASFAEK-------TAQLERSLQEEHVAVAQLREEA 1610
Query: 65 EHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRLAK 124
E Q E + + + ++ E+ R L Q + +K+ EA + +
Sbjct: 1611 ERRAQQQAEAERAREEAERELERWQLKANEALR-LRLQAEEVAQ--QKSLAQAEAEKQKE 1667
Query: 125 EAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAE 184
EA++E ++ E+AV +AEQ + + + T Q+
Sbjct: 1668 EAEREARRRGKAEEQAVRQRE-------LAEQELEKQRQLAEGTAQQ------------- 1707
Query: 185 EERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVT 244
RL E+E R+ +Q E + Q L++ L R ++ Q Q LE AKV
Sbjct: 1708 --RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREA----AAATQKRQELEAELAKVR 1761
Query: 245 ELEQQVAQAKTRYSVALRNLEQISEQ 270
+ + +K R R+ + S+Q
Sbjct: 1762 AEMEVLLASKARAEEESRSTSEKSKQ 1787
Score = 35.4 bits (80), Expect = 0.090
Identities = 46/192 (23%), Positives = 77/192 (40%), Gaps = 19/192 (9%)
Query: 29 RSPVAEEPGGGGSSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTY 88
R +AE EAKL + EE+ QE+ L Q ++ + Q L ++
Sbjct: 2449 REAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQ---LLQETQALQQSFLSEKDSLLQR 2505
Query: 89 RRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAR 148
R +++ KL E A+ A++L +E Q++ Q+ +R V+ AR
Sbjct: 2506 ERFIEQEKAKLEQLFQD-----EVAK----AQQLREEQQRQQQQMEQERQRLVASMEEAR 2556
Query: 149 EMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRG-----EREHQRVTRLCQQ 203
AE+GV + L Q+ ++ E +RLR E +H+ ++
Sbjct: 2557 RRQHEAEEGVRRKQEELQQLEQQRRQQE--ELLAEENQRLREQLQLLEEQHRAALAHSEE 2614
Query: 204 AEARVQALQKTL 215
A A KTL
Sbjct: 2615 VTASQVAATKTL 2626
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 49.3 bits (116), Expect = 6e-06
Identities = 57/233 (24%), Positives = 99/233 (42%), Gaps = 25/233 (10%)
Query: 51 REEEELDPRIQEELEHLNQAS-------EEINQVELQLDEARTTYRRILQESARKLN--T 101
R E + R+Q+ L +A+ EE+ +++ +++EAR R QESAR+L
Sbjct: 1985 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2044
Query: 102 QGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQG-VMA 160
+ + E+ + ++ +E QQ Q+ ++ AAR AE+ V A
Sbjct: 2045 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2104
Query: 161 DKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEA---RVQALQKTLRR 217
++ A + E ERL+ E Q R QA A R +A Q+ RR
Sbjct: 2105 EREA-----------AQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARR 2153
Query: 218 AIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQ 270
A + + +A ++ +E+HK + +Q AQ + + LE+ Q
Sbjct: 2154 AQAEQAALRQKQAADAE-MEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQ 2205
Score = 48.5 bits (114), Expect = 1e-05
Identities = 57/277 (20%), Positives = 114/277 (41%), Gaps = 21/277 (7%)
Query: 41 SSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLN 100
+ + KL E R +E+ + + +EEI + +L E T + L ++
Sbjct: 2384 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGE-KLHRTELATQEKVTLVQTLEIQR 2442
Query: 101 TQGSHLGSCI---------EKARPYYEAR--RLAKEAQQETQKAALRYERAVSMHN--AA 147
Q H + EK + EA+ +L E Q Q+ L E + +
Sbjct: 2443 QQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSE 2502
Query: 148 REMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEAR 207
++ + E+ + +K +L+ +Q+ + A E + ++ + E+E QR+ ++A R
Sbjct: 2503 KDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRR 2562
Query: 208 VQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQI 267
++ +RR + + + + Q ++L E + L +Q+ + ++ AL +
Sbjct: 2563 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR---LREQLQLLEEQHRAALAH---- 2615
Query: 268 SEQIHARRRGGLPPHPLGPRRSSPVGAEAGPEDMEDG 304
SE++ A + P G AEA PE DG
Sbjct: 2616 SEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDG 2652
Score = 45.4 bits (106), Expect = 9e-05
Identities = 59/246 (23%), Positives = 98/246 (39%), Gaps = 43/246 (17%)
Query: 51 REEEELDPR-----IQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQ--- 102
REE +D + IQEEL+ L Q+SE Q + + EA R ++E R + Q
Sbjct: 1408 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1467
Query: 103 -----GSHLGSC-----------IEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNA 146
G G +K + EA RL ++ Q E+Q+ +R + A
Sbjct: 1468 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQR-----KRQAEVELA 1522
Query: 147 AREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEA 206
+R AE +K R +E+ A E E RLR Q +Q +
Sbjct: 1523 SR---VKAEAEAAREKQRALQALEELRLQA-----EEAERRLR-----QAEVERARQVQV 1569
Query: 207 RVQALQKTLRRAIGKSRPYF-ELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLE 265
++ Q++ + R F E AQ + L+E V +L ++ + + + A R E
Sbjct: 1570 ALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERARE 1629
Query: 266 QISEQI 271
+ ++
Sbjct: 1630 EAEREL 1635
Score = 43.9 bits (102), Expect = 3e-04
Identities = 65/254 (25%), Positives = 107/254 (42%), Gaps = 41/254 (16%)
Query: 33 AEEPGGGGSSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRR-I 91
AE + EA++ E R EE E L Q++EE Q Q A R+
Sbjct: 2087 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2146
Query: 92 LQESARKLNTQGSHL------GSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHN 145
QE+AR+ + + L + +EK + + E + L ++AQ E + LR + + H
Sbjct: 2147 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAE-QTLRQKAQVEQELTTLRLQLEETDH- 2204
Query: 146 AAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAE 205
KN LD Q + AT EA +R + E E V R+ +
Sbjct: 2205 ---------------QKNLLDEELQRLKAEAT----EAARQRSQVEEELFSV-RVQMEEL 2244
Query: 206 ARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALR--- 262
++++A + RA+ K + L+E K+ +QVA+ R SVA +
Sbjct: 2245 SKLKARIEAENRAL-----ILRDKDNTQRFLQEEAEKM----KQVAEEAARLSVAAQEAA 2295
Query: 263 NLEQISEQIHARRR 276
L Q++E+ A++R
Sbjct: 2296 RLRQLAEEDLAQQR 2309
Score = 43.9 bits (102), Expect = 3e-04
Identities = 61/260 (23%), Positives = 110/260 (42%), Gaps = 37/260 (14%)
Query: 18 LRPEVVEDEVPRSPVAEEPGGGGSSSSEA--KLSPREEEELDPRIQ-EELEHLNQASEEI 74
LR ++ E + ++ + EE + ++EA + S EEE R+Q EEL L E
Sbjct: 2195 LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2254
Query: 75 NQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKE--AQQETQK 132
N+ + D+ T +R LQE A K+ A+ R+LA+E AQQ
Sbjct: 2255 NRALILRDKDNT--QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALA 2312
Query: 133 AALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGER 192
+ E+ ++ A R AE ++ + L + + RL+ ++
Sbjct: 2313 EKMLKEKMQAVQEATR---LKAEAELLQQQKELA---------------QEQARRLQEDK 2354
Query: 193 EHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQ 252
E ++ QQ Q Q+TL + + E+ A+ ++ K +V E+ + A+
Sbjct: 2355 E-----QMAQQLAEETQGFQRTLE---AERQRQLEMSAEAERL----KLRVAEMSRAQAR 2402
Query: 253 AKTRYSVALRNLEQISEQIH 272
A+ + E+I E++H
Sbjct: 2403 AEEDAQRFRKQAEEIGEKLH 2422
Score = 42.7 bits (99), Expect = 6e-04
Identities = 66/289 (22%), Positives = 103/289 (35%), Gaps = 51/289 (17%)
Query: 15 QGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKL------SPREEEELDPRIQEELEHLN 68
+ E + EDE + EE + E +L S E E +++ L
Sbjct: 1866 ENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR 1925
Query: 69 QASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSC----IEKARPYY---EARR 121
Q EEI ++ ++A + E R + L S +E AR E R
Sbjct: 1926 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 1985
Query: 122 LAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVN 181
+EA++ QK+ E A AA E V KV
Sbjct: 1986 RRREAEERVQKSLAAEEEAARQRKAALEEV----------------------ERLKAKVE 2023
Query: 182 EAEEERLRGEREHQRVTRLCQQ-AEARVQALQKTLRRAIGKSRPYFELKAQFSQIL---- 236
EA R R E+E R +L Q+ A+ R+QA +K A+ + + Q Q +
Sbjct: 2024 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2083
Query: 237 -----------EEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQIHAR 274
EE + + E++ AQ++ + A R + EQ AR
Sbjct: 2084 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQAR 2132
Score = 42.4 bits (98), Expect = 7e-04
Identities = 57/270 (21%), Positives = 104/270 (38%), Gaps = 44/270 (16%)
Query: 45 EAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQG- 103
+A+L P P++Q E + Q ++ +L + Y + + E+ R++ +
Sbjct: 1294 KAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEER 1353
Query: 104 -------------SHLGSCIEKARPYYE--------ARRLAKEAQQETQKAALRYERAV- 141
+ + + +EK R E A R AKE QQ Q+ +R E A
Sbjct: 1354 LAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAV 1413
Query: 142 ---------------SMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEE 186
++ E+ A Q A+++RL +E + ++ E +
Sbjct: 1414 DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRL--RIEEEIRVVRLQLEATERQ 1471
Query: 187 RLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTEL 246
R E E Q + ++AEA+ + Q+ R R + ++Q + E A +
Sbjct: 1472 RGGAEGELQALRARAEEAEAQKRQAQEEAERL----RRQVQDESQRKRQAEVELASRVKA 1527
Query: 247 EQQVAQAKTRYSVALRNLEQISEQIHARRR 276
E + A+ K R AL L +E+ R R
Sbjct: 1528 EAEAAREKQRALQALEELRLQAEEAERRLR 1557
Score = 38.5 bits (88), Expect = 0.011
Identities = 65/271 (23%), Positives = 108/271 (39%), Gaps = 33/271 (12%)
Query: 34 EEPGGGGSSSSEAKLSPREEEELDPR-IQEELEHLNQ----ASEEINQVELQL------- 81
E GG +A + EE E R QEE E L + S+ Q E++L
Sbjct: 1469 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1528
Query: 82 DEARTTYRRILQESARKLNTQGSHL-----GSCIEKARPYYEARRLAK---EAQQETQKA 133
EA +R LQ + +L Q + +E+AR A A+ EA+ ++++A
Sbjct: 1529 AEAAREKQRALQ-ALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRA 1587
Query: 134 ALRYERAVSMHNAAREMVFVAE--------QGVMADKNRLDPTWQEMLNHATCKVNEAEE 185
+ + A + E V VA+ A+ R + L K NEA
Sbjct: 1588 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1647
Query: 186 ERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTE 245
RL+ E Q+ + +AE + + ++ RR GK+ E + ++ E+ K +
Sbjct: 1648 LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR-GKAE---EQAVRQRELAEQELEKQRQ 1703
Query: 246 LEQQVAQAKTRYSVALRNLEQISEQIHARRR 276
L + AQ + L L +EQ +R+
Sbjct: 1704 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1734
Score = 36.6 bits (83), Expect = 0.040
Identities = 59/266 (22%), Positives = 106/266 (39%), Gaps = 39/266 (14%)
Query: 5 RQVPGGRETPQGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKLSPREEEELDPRIQEEL 64
RQV ET Q E+ + R+ AE+ +++ + S +EE +++EE
Sbjct: 1565 RQVQVALETAQRSAEAEL---QSKRASFAEK-------TAQLERSLQEEHVAVAQLREEA 1614
Query: 65 EHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRLAK 124
E Q E + + + ++ E+ R L Q + +K+ EA + +
Sbjct: 1615 ERRAQQQAEAERAREEAERELERWQLKANEALR-LRLQAEEVAQ--QKSLAQAEAEKQKE 1671
Query: 125 EAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAE 184
EA++E ++ E+AV +AEQ + + + T Q+
Sbjct: 1672 EAEREARRRGKAEEQAVRQRE-------LAEQELEKQRQLAEGTAQQ------------- 1711
Query: 185 EERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVT 244
RL E+E R+ +Q E + Q L++ L R ++ Q Q LE AKV
Sbjct: 1712 --RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREA----AAATQKRQELEAELAKVR 1765
Query: 245 ELEQQVAQAKTRYSVALRNLEQISEQ 270
+ + +K R R+ + S+Q
Sbjct: 1766 AEMEVLLASKARAEEESRSTSEKSKQ 1791
Score = 35.4 bits (80), Expect = 0.090
Identities = 46/192 (23%), Positives = 77/192 (40%), Gaps = 19/192 (9%)
Query: 29 RSPVAEEPGGGGSSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTY 88
R +AE EAKL + EE+ QE+ L Q ++ + Q L ++
Sbjct: 2453 REAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQ---LLQETQALQQSFLSEKDSLLQR 2509
Query: 89 RRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAR 148
R +++ KL E A+ A++L +E Q++ Q+ +R V+ AR
Sbjct: 2510 ERFIEQEKAKLEQLFQD-----EVAK----AQQLREEQQRQQQQMEQERQRLVASMEEAR 2560
Query: 149 EMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRG-----EREHQRVTRLCQQ 203
AE+GV + L Q+ ++ E +RLR E +H+ ++
Sbjct: 2561 RRQHEAEEGVRRKQEELQQLEQQRRQQE--ELLAEENQRLREQLQLLEEQHRAALAHSEE 2618
Query: 204 AEARVQALQKTL 215
A A KTL
Sbjct: 2619 VTASQVAATKTL 2630
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 49.3 bits (116), Expect = 6e-06
Identities = 57/233 (24%), Positives = 99/233 (42%), Gaps = 25/233 (10%)
Query: 51 REEEELDPRIQEELEHLNQAS-------EEINQVELQLDEARTTYRRILQESARKLN--T 101
R E + R+Q+ L +A+ EE+ +++ +++EAR R QESAR+L
Sbjct: 1981 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2040
Query: 102 QGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQG-VMA 160
+ + E+ + ++ +E QQ Q+ ++ AAR AE+ V A
Sbjct: 2041 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2100
Query: 161 DKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEA---RVQALQKTLRR 217
++ A + E ERL+ E Q R QA A R +A Q+ RR
Sbjct: 2101 EREA-----------AQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARR 2149
Query: 218 AIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQ 270
A + + +A ++ +E+HK + +Q AQ + + LE+ Q
Sbjct: 2150 AQAEQAALRQKQAADAE-MEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQ 2201
Score = 48.5 bits (114), Expect = 1e-05
Identities = 57/277 (20%), Positives = 114/277 (41%), Gaps = 21/277 (7%)
Query: 41 SSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLN 100
+ + KL E R +E+ + + +EEI + +L E T + L ++
Sbjct: 2380 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGE-KLHRTELATQEKVTLVQTLEIQR 2438
Query: 101 TQGSHLGSCI---------EKARPYYEAR--RLAKEAQQETQKAALRYERAVSMHN--AA 147
Q H + EK + EA+ +L E Q Q+ L E + +
Sbjct: 2439 QQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSE 2498
Query: 148 REMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEAR 207
++ + E+ + +K +L+ +Q+ + A E + ++ + E+E QR+ ++A R
Sbjct: 2499 KDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRR 2558
Query: 208 VQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQI 267
++ +RR + + + + Q ++L E + L +Q+ + ++ AL +
Sbjct: 2559 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR---LREQLQLLEEQHRAALAH---- 2611
Query: 268 SEQIHARRRGGLPPHPLGPRRSSPVGAEAGPEDMEDG 304
SE++ A + P G AEA PE DG
Sbjct: 2612 SEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDG 2648
Score = 45.4 bits (106), Expect = 9e-05
Identities = 59/246 (23%), Positives = 98/246 (39%), Gaps = 43/246 (17%)
Query: 51 REEEELDPR-----IQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQ--- 102
REE +D + IQEEL+ L Q+SE Q + + EA R ++E R + Q
Sbjct: 1404 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1463
Query: 103 -----GSHLGSC-----------IEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNA 146
G G +K + EA RL ++ Q E+Q+ +R + A
Sbjct: 1464 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQR-----KRQAEVELA 1518
Query: 147 AREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEA 206
+R AE +K R +E+ A E E RLR Q +Q +
Sbjct: 1519 SR---VKAEAEAAREKQRALQALEELRLQA-----EEAERRLR-----QAEVERARQVQV 1565
Query: 207 RVQALQKTLRRAIGKSRPYF-ELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLE 265
++ Q++ + R F E AQ + L+E V +L ++ + + + A R E
Sbjct: 1566 ALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERARE 1625
Query: 266 QISEQI 271
+ ++
Sbjct: 1626 EAEREL 1631
Score = 43.9 bits (102), Expect = 3e-04
Identities = 65/254 (25%), Positives = 107/254 (42%), Gaps = 41/254 (16%)
Query: 33 AEEPGGGGSSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRR-I 91
AE + EA++ E R EE E L Q++EE Q Q A R+
Sbjct: 2083 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2142
Query: 92 LQESARKLNTQGSHL------GSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHN 145
QE+AR+ + + L + +EK + + E + L ++AQ E + LR + + H
Sbjct: 2143 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAE-QTLRQKAQVEQELTTLRLQLEETDH- 2200
Query: 146 AAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAE 205
KN LD Q + AT EA +R + E E V R+ +
Sbjct: 2201 ---------------QKNLLDEELQRLKAEAT----EAARQRSQVEEELFSV-RVQMEEL 2240
Query: 206 ARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALR--- 262
++++A + RA+ K + L+E K+ +QVA+ R SVA +
Sbjct: 2241 SKLKARIEAENRAL-----ILRDKDNTQRFLQEEAEKM----KQVAEEAARLSVAAQEAA 2291
Query: 263 NLEQISEQIHARRR 276
L Q++E+ A++R
Sbjct: 2292 RLRQLAEEDLAQQR 2305
Score = 43.9 bits (102), Expect = 3e-04
Identities = 61/260 (23%), Positives = 110/260 (42%), Gaps = 37/260 (14%)
Query: 18 LRPEVVEDEVPRSPVAEEPGGGGSSSSEA--KLSPREEEELDPRIQ-EELEHLNQASEEI 74
LR ++ E + ++ + EE + ++EA + S EEE R+Q EEL L E
Sbjct: 2191 LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2250
Query: 75 NQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKE--AQQETQK 132
N+ + D+ T +R LQE A K+ A+ R+LA+E AQQ
Sbjct: 2251 NRALILRDKDNT--QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALA 2308
Query: 133 AALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGER 192
+ E+ ++ A R AE ++ + L + + RL+ ++
Sbjct: 2309 EKMLKEKMQAVQEATR---LKAEAELLQQQKELA---------------QEQARRLQEDK 2350
Query: 193 EHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQ 252
E ++ QQ Q Q+TL + + E+ A+ ++ K +V E+ + A+
Sbjct: 2351 E-----QMAQQLAEETQGFQRTLE---AERQRQLEMSAEAERL----KLRVAEMSRAQAR 2398
Query: 253 AKTRYSVALRNLEQISEQIH 272
A+ + E+I E++H
Sbjct: 2399 AEEDAQRFRKQAEEIGEKLH 2418
Score = 42.7 bits (99), Expect = 6e-04
Identities = 66/289 (22%), Positives = 103/289 (35%), Gaps = 51/289 (17%)
Query: 15 QGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKL------SPREEEELDPRIQEELEHLN 68
+ E + EDE + EE + E +L S E E +++ L
Sbjct: 1862 ENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR 1921
Query: 69 QASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSC----IEKARPYY---EARR 121
Q EEI ++ ++A + E R + L S +E AR E R
Sbjct: 1922 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 1981
Query: 122 LAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVN 181
+EA++ QK+ E A AA E V KV
Sbjct: 1982 RRREAEERVQKSLAAEEEAARQRKAALEEV----------------------ERLKAKVE 2019
Query: 182 EAEEERLRGEREHQRVTRLCQQ-AEARVQALQKTLRRAIGKSRPYFELKAQFSQIL---- 236
EA R R E+E R +L Q+ A+ R+QA +K A+ + + Q Q +
Sbjct: 2020 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2079
Query: 237 -----------EEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQIHAR 274
EE + + E++ AQ++ + A R + EQ AR
Sbjct: 2080 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQAR 2128
Score = 42.4 bits (98), Expect = 7e-04
Identities = 57/270 (21%), Positives = 104/270 (38%), Gaps = 44/270 (16%)
Query: 45 EAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQG- 103
+A+L P P++Q E + Q ++ +L + Y + + E+ R++ +
Sbjct: 1290 KAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEER 1349
Query: 104 -------------SHLGSCIEKARPYYE--------ARRLAKEAQQETQKAALRYERAV- 141
+ + + +EK R E A R AKE QQ Q+ +R E A
Sbjct: 1350 LAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAV 1409
Query: 142 ---------------SMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEE 186
++ E+ A Q A+++RL +E + ++ E +
Sbjct: 1410 DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRL--RIEEEIRVVRLQLEATERQ 1467
Query: 187 RLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTEL 246
R E E Q + ++AEA+ + Q+ R R + ++Q + E A +
Sbjct: 1468 RGGAEGELQALRARAEEAEAQKRQAQEEAERL----RRQVQDESQRKRQAEVELASRVKA 1523
Query: 247 EQQVAQAKTRYSVALRNLEQISEQIHARRR 276
E + A+ K R AL L +E+ R R
Sbjct: 1524 EAEAAREKQRALQALEELRLQAEEAERRLR 1553
Score = 38.5 bits (88), Expect = 0.011
Identities = 65/271 (23%), Positives = 108/271 (39%), Gaps = 33/271 (12%)
Query: 34 EEPGGGGSSSSEAKLSPREEEELDPR-IQEELEHLNQ----ASEEINQVELQL------- 81
E GG +A + EE E R QEE E L + S+ Q E++L
Sbjct: 1465 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1524
Query: 82 DEARTTYRRILQESARKLNTQGSHL-----GSCIEKARPYYEARRLAK---EAQQETQKA 133
EA +R LQ + +L Q + +E+AR A A+ EA+ ++++A
Sbjct: 1525 AEAAREKQRALQ-ALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRA 1583
Query: 134 ALRYERAVSMHNAAREMVFVAE--------QGVMADKNRLDPTWQEMLNHATCKVNEAEE 185
+ + A + E V VA+ A+ R + L K NEA
Sbjct: 1584 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1643
Query: 186 ERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTE 245
RL+ E Q+ + +AE + + ++ RR GK+ E + ++ E+ K +
Sbjct: 1644 LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR-GKAE---EQAVRQRELAEQELEKQRQ 1699
Query: 246 LEQQVAQAKTRYSVALRNLEQISEQIHARRR 276
L + AQ + L L +EQ +R+
Sbjct: 1700 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1730
Score = 36.6 bits (83), Expect = 0.040
Identities = 59/266 (22%), Positives = 106/266 (39%), Gaps = 39/266 (14%)
Query: 5 RQVPGGRETPQGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKLSPREEEELDPRIQEEL 64
RQV ET Q E+ + R+ AE+ +++ + S +EE +++EE
Sbjct: 1561 RQVQVALETAQRSAEAEL---QSKRASFAEK-------TAQLERSLQEEHVAVAQLREEA 1610
Query: 65 EHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRLAK 124
E Q E + + + ++ E+ R L Q + +K+ EA + +
Sbjct: 1611 ERRAQQQAEAERAREEAERELERWQLKANEALR-LRLQAEEVAQ--QKSLAQAEAEKQKE 1667
Query: 125 EAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAE 184
EA++E ++ E+AV +AEQ + + + T Q+
Sbjct: 1668 EAEREARRRGKAEEQAVRQRE-------LAEQELEKQRQLAEGTAQQ------------- 1707
Query: 185 EERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVT 244
RL E+E R+ +Q E + Q L++ L R ++ Q Q LE AKV
Sbjct: 1708 --RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREA----AAATQKRQELEAELAKVR 1761
Query: 245 ELEQQVAQAKTRYSVALRNLEQISEQ 270
+ + +K R R+ + S+Q
Sbjct: 1762 AEMEVLLASKARAEEESRSTSEKSKQ 1787
Score = 35.4 bits (80), Expect = 0.090
Identities = 46/192 (23%), Positives = 77/192 (40%), Gaps = 19/192 (9%)
Query: 29 RSPVAEEPGGGGSSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTY 88
R +AE EAKL + EE+ QE+ L Q ++ + Q L ++
Sbjct: 2449 REAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQ---LLQETQALQQSFLSEKDSLLQR 2505
Query: 89 RRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAR 148
R +++ KL E A+ A++L +E Q++ Q+ +R V+ AR
Sbjct: 2506 ERFIEQEKAKLEQLFQD-----EVAK----AQQLREEQQRQQQQMEQERQRLVASMEEAR 2556
Query: 149 EMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRG-----EREHQRVTRLCQQ 203
AE+GV + L Q+ ++ E +RLR E +H+ ++
Sbjct: 2557 RRQHEAEEGVRRKQEELQQLEQQRRQQE--ELLAEENQRLREQLQLLEEQHRAALAHSEE 2614
Query: 204 AEARVQALQKTL 215
A A KTL
Sbjct: 2615 VTASQVAATKTL 2626
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 49.3 bits (116), Expect = 6e-06
Identities = 57/233 (24%), Positives = 99/233 (42%), Gaps = 25/233 (10%)
Query: 51 REEEELDPRIQEELEHLNQAS-------EEINQVELQLDEARTTYRRILQESARKLN--T 101
R E + R+Q+ L +A+ EE+ +++ +++EAR R QESAR+L
Sbjct: 1949 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2008
Query: 102 QGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQG-VMA 160
+ + E+ + ++ +E QQ Q+ ++ AAR AE+ V A
Sbjct: 2009 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2068
Query: 161 DKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEA---RVQALQKTLRR 217
++ A + E ERL+ E Q R QA A R +A Q+ RR
Sbjct: 2069 EREA-----------AQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARR 2117
Query: 218 AIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQ 270
A + + +A ++ +E+HK + +Q AQ + + LE+ Q
Sbjct: 2118 AQAEQAALRQKQAADAE-MEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQ 2169
Score = 48.5 bits (114), Expect = 1e-05
Identities = 57/277 (20%), Positives = 114/277 (41%), Gaps = 21/277 (7%)
Query: 41 SSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLN 100
+ + KL E R +E+ + + +EEI + +L E T + L ++
Sbjct: 2348 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGE-KLHRTELATQEKVTLVQTLEIQR 2406
Query: 101 TQGSHLGSCI---------EKARPYYEAR--RLAKEAQQETQKAALRYERAVSMHN--AA 147
Q H + EK + EA+ +L E Q Q+ L E + +
Sbjct: 2407 QQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSE 2466
Query: 148 REMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEAR 207
++ + E+ + +K +L+ +Q+ + A E + ++ + E+E QR+ ++A R
Sbjct: 2467 KDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRR 2526
Query: 208 VQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQI 267
++ +RR + + + + Q ++L E + L +Q+ + ++ AL +
Sbjct: 2527 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR---LREQLQLLEEQHRAALAH---- 2579
Query: 268 SEQIHARRRGGLPPHPLGPRRSSPVGAEAGPEDMEDG 304
SE++ A + P G AEA PE DG
Sbjct: 2580 SEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDG 2616
Score = 45.4 bits (106), Expect = 9e-05
Identities = 59/246 (23%), Positives = 98/246 (39%), Gaps = 43/246 (17%)
Query: 51 REEEELDPR-----IQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQ--- 102
REE +D + IQEEL+ L Q+SE Q + + EA R ++E R + Q
Sbjct: 1372 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1431
Query: 103 -----GSHLGSC-----------IEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNA 146
G G +K + EA RL ++ Q E+Q+ +R + A
Sbjct: 1432 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQR-----KRQAEVELA 1486
Query: 147 AREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEA 206
+R AE +K R +E+ A E E RLR Q +Q +
Sbjct: 1487 SR---VKAEAEAAREKQRALQALEELRLQA-----EEAERRLR-----QAEVERARQVQV 1533
Query: 207 RVQALQKTLRRAIGKSRPYF-ELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLE 265
++ Q++ + R F E AQ + L+E V +L ++ + + + A R E
Sbjct: 1534 ALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERARE 1593
Query: 266 QISEQI 271
+ ++
Sbjct: 1594 EAEREL 1599
Score = 43.9 bits (102), Expect = 3e-04
Identities = 65/254 (25%), Positives = 107/254 (42%), Gaps = 41/254 (16%)
Query: 33 AEEPGGGGSSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRR-I 91
AE + EA++ E R EE E L Q++EE Q Q A R+
Sbjct: 2051 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2110
Query: 92 LQESARKLNTQGSHL------GSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHN 145
QE+AR+ + + L + +EK + + E + L ++AQ E + LR + + H
Sbjct: 2111 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAE-QTLRQKAQVEQELTTLRLQLEETDH- 2168
Query: 146 AAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAE 205
KN LD Q + AT EA +R + E E V R+ +
Sbjct: 2169 ---------------QKNLLDEELQRLKAEAT----EAARQRSQVEEELFSV-RVQMEEL 2208
Query: 206 ARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALR--- 262
++++A + RA+ K + L+E K+ +QVA+ R SVA +
Sbjct: 2209 SKLKARIEAENRAL-----ILRDKDNTQRFLQEEAEKM----KQVAEEAARLSVAAQEAA 2259
Query: 263 NLEQISEQIHARRR 276
L Q++E+ A++R
Sbjct: 2260 RLRQLAEEDLAQQR 2273
Score = 43.9 bits (102), Expect = 3e-04
Identities = 61/260 (23%), Positives = 110/260 (42%), Gaps = 37/260 (14%)
Query: 18 LRPEVVEDEVPRSPVAEEPGGGGSSSSEA--KLSPREEEELDPRIQ-EELEHLNQASEEI 74
LR ++ E + ++ + EE + ++EA + S EEE R+Q EEL L E
Sbjct: 2159 LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2218
Query: 75 NQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKE--AQQETQK 132
N+ + D+ T +R LQE A K+ A+ R+LA+E AQQ
Sbjct: 2219 NRALILRDKDNT--QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALA 2276
Query: 133 AALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGER 192
+ E+ ++ A R AE ++ + L + + RL+ ++
Sbjct: 2277 EKMLKEKMQAVQEATR---LKAEAELLQQQKELA---------------QEQARRLQEDK 2318
Query: 193 EHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQ 252
E ++ QQ Q Q+TL + + E+ A+ ++ K +V E+ + A+
Sbjct: 2319 E-----QMAQQLAEETQGFQRTLE---AERQRQLEMSAEAERL----KLRVAEMSRAQAR 2366
Query: 253 AKTRYSVALRNLEQISEQIH 272
A+ + E+I E++H
Sbjct: 2367 AEEDAQRFRKQAEEIGEKLH 2386
Score = 42.7 bits (99), Expect = 6e-04
Identities = 66/289 (22%), Positives = 103/289 (35%), Gaps = 51/289 (17%)
Query: 15 QGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKL------SPREEEELDPRIQEELEHLN 68
+ E + EDE + EE + E +L S E E +++ L
Sbjct: 1830 ENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR 1889
Query: 69 QASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSC----IEKARPYY---EARR 121
Q EEI ++ ++A + E R + L S +E AR E R
Sbjct: 1890 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 1949
Query: 122 LAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVN 181
+EA++ QK+ E A AA E V KV
Sbjct: 1950 RRREAEERVQKSLAAEEEAARQRKAALEEV----------------------ERLKAKVE 1987
Query: 182 EAEEERLRGEREHQRVTRLCQQ-AEARVQALQKTLRRAIGKSRPYFELKAQFSQIL---- 236
EA R R E+E R +L Q+ A+ R+QA +K A+ + + Q Q +
Sbjct: 1988 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2047
Query: 237 -----------EEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQIHAR 274
EE + + E++ AQ++ + A R + EQ AR
Sbjct: 2048 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQAR 2096
Score = 42.4 bits (98), Expect = 7e-04
Identities = 57/270 (21%), Positives = 104/270 (38%), Gaps = 44/270 (16%)
Query: 45 EAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQG- 103
+A+L P P++Q E + Q ++ +L + Y + + E+ R++ +
Sbjct: 1258 KAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEER 1317
Query: 104 -------------SHLGSCIEKARPYYE--------ARRLAKEAQQETQKAALRYERAV- 141
+ + + +EK R E A R AKE QQ Q+ +R E A
Sbjct: 1318 LAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAV 1377
Query: 142 ---------------SMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEE 186
++ E+ A Q A+++RL +E + ++ E +
Sbjct: 1378 DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRL--RIEEEIRVVRLQLEATERQ 1435
Query: 187 RLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTEL 246
R E E Q + ++AEA+ + Q+ R R + ++Q + E A +
Sbjct: 1436 RGGAEGELQALRARAEEAEAQKRQAQEEAERL----RRQVQDESQRKRQAEVELASRVKA 1491
Query: 247 EQQVAQAKTRYSVALRNLEQISEQIHARRR 276
E + A+ K R AL L +E+ R R
Sbjct: 1492 EAEAAREKQRALQALEELRLQAEEAERRLR 1521
Score = 38.5 bits (88), Expect = 0.011
Identities = 65/271 (23%), Positives = 108/271 (39%), Gaps = 33/271 (12%)
Query: 34 EEPGGGGSSSSEAKLSPREEEELDPR-IQEELEHLNQ----ASEEINQVELQL------- 81
E GG +A + EE E R QEE E L + S+ Q E++L
Sbjct: 1433 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1492
Query: 82 DEARTTYRRILQESARKLNTQGSHL-----GSCIEKARPYYEARRLAK---EAQQETQKA 133
EA +R LQ + +L Q + +E+AR A A+ EA+ ++++A
Sbjct: 1493 AEAAREKQRALQ-ALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRA 1551
Query: 134 ALRYERAVSMHNAAREMVFVAE--------QGVMADKNRLDPTWQEMLNHATCKVNEAEE 185
+ + A + E V VA+ A+ R + L K NEA
Sbjct: 1552 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1611
Query: 186 ERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTE 245
RL+ E Q+ + +AE + + ++ RR GK+ E + ++ E+ K +
Sbjct: 1612 LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR-GKAE---EQAVRQRELAEQELEKQRQ 1667
Query: 246 LEQQVAQAKTRYSVALRNLEQISEQIHARRR 276
L + AQ + L L +EQ +R+
Sbjct: 1668 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1698
Score = 36.6 bits (83), Expect = 0.040
Identities = 59/266 (22%), Positives = 106/266 (39%), Gaps = 39/266 (14%)
Query: 5 RQVPGGRETPQGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKLSPREEEELDPRIQEEL 64
RQV ET Q E+ + R+ AE+ +++ + S +EE +++EE
Sbjct: 1529 RQVQVALETAQRSAEAEL---QSKRASFAEK-------TAQLERSLQEEHVAVAQLREEA 1578
Query: 65 EHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRLAK 124
E Q E + + + ++ E+ R L Q + +K+ EA + +
Sbjct: 1579 ERRAQQQAEAERAREEAERELERWQLKANEALR-LRLQAEEVAQ--QKSLAQAEAEKQKE 1635
Query: 125 EAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAE 184
EA++E ++ E+AV +AEQ + + + T Q+
Sbjct: 1636 EAEREARRRGKAEEQAVRQRE-------LAEQELEKQRQLAEGTAQQ------------- 1675
Query: 185 EERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVT 244
RL E+E R+ +Q E + Q L++ L R ++ Q Q LE AKV
Sbjct: 1676 --RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREA----AAATQKRQELEAELAKVR 1729
Query: 245 ELEQQVAQAKTRYSVALRNLEQISEQ 270
+ + +K R R+ + S+Q
Sbjct: 1730 AEMEVLLASKARAEEESRSTSEKSKQ 1755
Score = 35.4 bits (80), Expect = 0.090
Identities = 46/192 (23%), Positives = 77/192 (40%), Gaps = 19/192 (9%)
Query: 29 RSPVAEEPGGGGSSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTY 88
R +AE EAKL + EE+ QE+ L Q ++ + Q L ++
Sbjct: 2417 REAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQ---LLQETQALQQSFLSEKDSLLQR 2473
Query: 89 RRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAR 148
R +++ KL E A+ A++L +E Q++ Q+ +R V+ AR
Sbjct: 2474 ERFIEQEKAKLEQLFQD-----EVAK----AQQLREEQQRQQQQMEQERQRLVASMEEAR 2524
Query: 149 EMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRG-----EREHQRVTRLCQQ 203
AE+GV + L Q+ ++ E +RLR E +H+ ++
Sbjct: 2525 RRQHEAEEGVRRKQEELQQLEQQRRQQE--ELLAEENQRLREQLQLLEEQHRAALAHSEE 2582
Query: 204 AEARVQALQKTL 215
A A KTL
Sbjct: 2583 VTASQVAATKTL 2594
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 49.3 bits (116), Expect = 6e-06
Identities = 57/233 (24%), Positives = 99/233 (42%), Gaps = 25/233 (10%)
Query: 51 REEEELDPRIQEELEHLNQAS-------EEINQVELQLDEARTTYRRILQESARKLN--T 101
R E + R+Q+ L +A+ EE+ +++ +++EAR R QESAR+L
Sbjct: 2118 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2177
Query: 102 QGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQG-VMA 160
+ + E+ + ++ +E QQ Q+ ++ AAR AE+ V A
Sbjct: 2178 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2237
Query: 161 DKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEA---RVQALQKTLRR 217
++ A + E ERL+ E Q R QA A R +A Q+ RR
Sbjct: 2238 EREA-----------AQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARR 2286
Query: 218 AIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQ 270
A + + +A ++ +E+HK + +Q AQ + + LE+ Q
Sbjct: 2287 AQAEQAALRQKQAADAE-MEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQ 2338
Score = 48.5 bits (114), Expect = 1e-05
Identities = 57/277 (20%), Positives = 114/277 (41%), Gaps = 21/277 (7%)
Query: 41 SSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLN 100
+ + KL E R +E+ + + +EEI + +L E T + L ++
Sbjct: 2517 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGE-KLHRTELATQEKVTLVQTLEIQR 2575
Query: 101 TQGSHLGSCI---------EKARPYYEAR--RLAKEAQQETQKAALRYERAVSMHN--AA 147
Q H + EK + EA+ +L E Q Q+ L E + +
Sbjct: 2576 QQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSE 2635
Query: 148 REMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEAR 207
++ + E+ + +K +L+ +Q+ + A E + ++ + E+E QR+ ++A R
Sbjct: 2636 KDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRR 2695
Query: 208 VQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQI 267
++ +RR + + + + Q ++L E + L +Q+ + ++ AL +
Sbjct: 2696 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR---LREQLQLLEEQHRAALAH---- 2748
Query: 268 SEQIHARRRGGLPPHPLGPRRSSPVGAEAGPEDMEDG 304
SE++ A + P G AEA PE DG
Sbjct: 2749 SEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDG 2785
Score = 45.4 bits (106), Expect = 9e-05
Identities = 59/246 (23%), Positives = 98/246 (39%), Gaps = 43/246 (17%)
Query: 51 REEEELDPR-----IQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQ--- 102
REE +D + IQEEL+ L Q+SE Q + + EA R ++E R + Q
Sbjct: 1541 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1600
Query: 103 -----GSHLGSC-----------IEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNA 146
G G +K + EA RL ++ Q E+Q+ +R + A
Sbjct: 1601 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQR-----KRQAEVELA 1655
Query: 147 AREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEA 206
+R AE +K R +E+ A E E RLR Q +Q +
Sbjct: 1656 SR---VKAEAEAAREKQRALQALEELRLQA-----EEAERRLR-----QAEVERARQVQV 1702
Query: 207 RVQALQKTLRRAIGKSRPYF-ELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLE 265
++ Q++ + R F E AQ + L+E V +L ++ + + + A R E
Sbjct: 1703 ALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERARE 1762
Query: 266 QISEQI 271
+ ++
Sbjct: 1763 EAEREL 1768
Score = 43.9 bits (102), Expect = 3e-04
Identities = 65/254 (25%), Positives = 107/254 (42%), Gaps = 41/254 (16%)
Query: 33 AEEPGGGGSSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRR-I 91
AE + EA++ E R EE E L Q++EE Q Q A R+
Sbjct: 2220 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2279
Query: 92 LQESARKLNTQGSHL------GSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHN 145
QE+AR+ + + L + +EK + + E + L ++AQ E + LR + + H
Sbjct: 2280 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAE-QTLRQKAQVEQELTTLRLQLEETDH- 2337
Query: 146 AAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAE 205
KN LD Q + AT EA +R + E E V R+ +
Sbjct: 2338 ---------------QKNLLDEELQRLKAEAT----EAARQRSQVEEELFSV-RVQMEEL 2377
Query: 206 ARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALR--- 262
++++A + RA+ K + L+E K+ +QVA+ R SVA +
Sbjct: 2378 SKLKARIEAENRAL-----ILRDKDNTQRFLQEEAEKM----KQVAEEAARLSVAAQEAA 2428
Query: 263 NLEQISEQIHARRR 276
L Q++E+ A++R
Sbjct: 2429 RLRQLAEEDLAQQR 2442
Score = 43.9 bits (102), Expect = 3e-04
Identities = 61/260 (23%), Positives = 110/260 (42%), Gaps = 37/260 (14%)
Query: 18 LRPEVVEDEVPRSPVAEEPGGGGSSSSEA--KLSPREEEELDPRIQ-EELEHLNQASEEI 74
LR ++ E + ++ + EE + ++EA + S EEE R+Q EEL L E
Sbjct: 2328 LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2387
Query: 75 NQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKE--AQQETQK 132
N+ + D+ T +R LQE A K+ A+ R+LA+E AQQ
Sbjct: 2388 NRALILRDKDNT--QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALA 2445
Query: 133 AALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGER 192
+ E+ ++ A R AE ++ + L + + RL+ ++
Sbjct: 2446 EKMLKEKMQAVQEATR---LKAEAELLQQQKELA---------------QEQARRLQEDK 2487
Query: 193 EHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQ 252
E ++ QQ Q Q+TL + + E+ A+ ++ K +V E+ + A+
Sbjct: 2488 E-----QMAQQLAEETQGFQRTLE---AERQRQLEMSAEAERL----KLRVAEMSRAQAR 2535
Query: 253 AKTRYSVALRNLEQISEQIH 272
A+ + E+I E++H
Sbjct: 2536 AEEDAQRFRKQAEEIGEKLH 2555
Score = 42.7 bits (99), Expect = 6e-04
Identities = 66/289 (22%), Positives = 103/289 (35%), Gaps = 51/289 (17%)
Query: 15 QGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKL------SPREEEELDPRIQEELEHLN 68
+ E + EDE + EE + E +L S E E +++ L
Sbjct: 1999 ENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR 2058
Query: 69 QASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSC----IEKARPYY---EARR 121
Q EEI ++ ++A + E R + L S +E AR E R
Sbjct: 2059 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 2118
Query: 122 LAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVN 181
+EA++ QK+ E A AA E V KV
Sbjct: 2119 RRREAEERVQKSLAAEEEAARQRKAALEEV----------------------ERLKAKVE 2156
Query: 182 EAEEERLRGEREHQRVTRLCQQ-AEARVQALQKTLRRAIGKSRPYFELKAQFSQIL---- 236
EA R R E+E R +L Q+ A+ R+QA +K A+ + + Q Q +
Sbjct: 2157 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2216
Query: 237 -----------EEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQIHAR 274
EE + + E++ AQ++ + A R + EQ AR
Sbjct: 2217 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQAR 2265
Score = 42.4 bits (98), Expect = 7e-04
Identities = 57/270 (21%), Positives = 104/270 (38%), Gaps = 44/270 (16%)
Query: 45 EAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQG- 103
+A+L P P++Q E + Q ++ +L + Y + + E+ R++ +
Sbjct: 1427 KAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEER 1486
Query: 104 -------------SHLGSCIEKARPYYE--------ARRLAKEAQQETQKAALRYERAV- 141
+ + + +EK R E A R AKE QQ Q+ +R E A
Sbjct: 1487 LAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAV 1546
Query: 142 ---------------SMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEE 186
++ E+ A Q A+++RL +E + ++ E +
Sbjct: 1547 DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRL--RIEEEIRVVRLQLEATERQ 1604
Query: 187 RLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTEL 246
R E E Q + ++AEA+ + Q+ R R + ++Q + E A +
Sbjct: 1605 RGGAEGELQALRARAEEAEAQKRQAQEEAERL----RRQVQDESQRKRQAEVELASRVKA 1660
Query: 247 EQQVAQAKTRYSVALRNLEQISEQIHARRR 276
E + A+ K R AL L +E+ R R
Sbjct: 1661 EAEAAREKQRALQALEELRLQAEEAERRLR 1690
Score = 38.5 bits (88), Expect = 0.011
Identities = 65/271 (23%), Positives = 108/271 (39%), Gaps = 33/271 (12%)
Query: 34 EEPGGGGSSSSEAKLSPREEEELDPR-IQEELEHLNQ----ASEEINQVELQL------- 81
E GG +A + EE E R QEE E L + S+ Q E++L
Sbjct: 1602 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1661
Query: 82 DEARTTYRRILQESARKLNTQGSHL-----GSCIEKARPYYEARRLAK---EAQQETQKA 133
EA +R LQ + +L Q + +E+AR A A+ EA+ ++++A
Sbjct: 1662 AEAAREKQRALQ-ALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRA 1720
Query: 134 ALRYERAVSMHNAAREMVFVAE--------QGVMADKNRLDPTWQEMLNHATCKVNEAEE 185
+ + A + E V VA+ A+ R + L K NEA
Sbjct: 1721 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1780
Query: 186 ERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTE 245
RL+ E Q+ + +AE + + ++ RR GK+ E + ++ E+ K +
Sbjct: 1781 LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR-GKAE---EQAVRQRELAEQELEKQRQ 1836
Query: 246 LEQQVAQAKTRYSVALRNLEQISEQIHARRR 276
L + AQ + L L +EQ +R+
Sbjct: 1837 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1867
Score = 36.6 bits (83), Expect = 0.040
Identities = 59/266 (22%), Positives = 106/266 (39%), Gaps = 39/266 (14%)
Query: 5 RQVPGGRETPQGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKLSPREEEELDPRIQEEL 64
RQV ET Q E+ + R+ AE+ +++ + S +EE +++EE
Sbjct: 1698 RQVQVALETAQRSAEAEL---QSKRASFAEK-------TAQLERSLQEEHVAVAQLREEA 1747
Query: 65 EHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRLAK 124
E Q E + + + ++ E+ R L Q + +K+ EA + +
Sbjct: 1748 ERRAQQQAEAERAREEAERELERWQLKANEALR-LRLQAEEVAQ--QKSLAQAEAEKQKE 1804
Query: 125 EAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAE 184
EA++E ++ E+AV +AEQ + + + T Q+
Sbjct: 1805 EAEREARRRGKAEEQAVRQRE-------LAEQELEKQRQLAEGTAQQ------------- 1844
Query: 185 EERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVT 244
RL E+E R+ +Q E + Q L++ L R ++ Q Q LE AKV
Sbjct: 1845 --RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREA----AAATQKRQELEAELAKVR 1898
Query: 245 ELEQQVAQAKTRYSVALRNLEQISEQ 270
+ + +K R R+ + S+Q
Sbjct: 1899 AEMEVLLASKARAEEESRSTSEKSKQ 1924
Score = 35.4 bits (80), Expect = 0.090
Identities = 46/192 (23%), Positives = 77/192 (40%), Gaps = 19/192 (9%)
Query: 29 RSPVAEEPGGGGSSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTY 88
R +AE EAKL + EE+ QE+ L Q ++ + Q L ++
Sbjct: 2586 REAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQ---LLQETQALQQSFLSEKDSLLQR 2642
Query: 89 RRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAR 148
R +++ KL E A+ A++L +E Q++ Q+ +R V+ AR
Sbjct: 2643 ERFIEQEKAKLEQLFQD-----EVAK----AQQLREEQQRQQQQMEQERQRLVASMEEAR 2693
Query: 149 EMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRG-----EREHQRVTRLCQQ 203
AE+GV + L Q+ ++ E +RLR E +H+ ++
Sbjct: 2694 RRQHEAEEGVRRKQEELQQLEQQRRQQE--ELLAEENQRLREQLQLLEEQHRAALAHSEE 2751
Query: 204 AEARVQALQKTL 215
A A KTL
Sbjct: 2752 VTASQVAATKTL 2763
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 49.3 bits (116), Expect = 6e-06
Identities = 57/233 (24%), Positives = 99/233 (42%), Gaps = 25/233 (10%)
Query: 51 REEEELDPRIQEELEHLNQAS-------EEINQVELQLDEARTTYRRILQESARKLN--T 101
R E + R+Q+ L +A+ EE+ +++ +++EAR R QESAR+L
Sbjct: 1959 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2018
Query: 102 QGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQG-VMA 160
+ + E+ + ++ +E QQ Q+ ++ AAR AE+ V A
Sbjct: 2019 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2078
Query: 161 DKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEA---RVQALQKTLRR 217
++ A + E ERL+ E Q R QA A R +A Q+ RR
Sbjct: 2079 EREA-----------AQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARR 2127
Query: 218 AIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQ 270
A + + +A ++ +E+HK + +Q AQ + + LE+ Q
Sbjct: 2128 AQAEQAALRQKQAADAE-MEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQ 2179
Score = 48.5 bits (114), Expect = 1e-05
Identities = 57/277 (20%), Positives = 114/277 (41%), Gaps = 21/277 (7%)
Query: 41 SSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLN 100
+ + KL E R +E+ + + +EEI + +L E T + L ++
Sbjct: 2358 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGE-KLHRTELATQEKVTLVQTLEIQR 2416
Query: 101 TQGSHLGSCI---------EKARPYYEAR--RLAKEAQQETQKAALRYERAVSMHN--AA 147
Q H + EK + EA+ +L E Q Q+ L E + +
Sbjct: 2417 QQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSE 2476
Query: 148 REMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEAR 207
++ + E+ + +K +L+ +Q+ + A E + ++ + E+E QR+ ++A R
Sbjct: 2477 KDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRR 2536
Query: 208 VQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQI 267
++ +RR + + + + Q ++L E + L +Q+ + ++ AL +
Sbjct: 2537 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR---LREQLQLLEEQHRAALAH---- 2589
Query: 268 SEQIHARRRGGLPPHPLGPRRSSPVGAEAGPEDMEDG 304
SE++ A + P G AEA PE DG
Sbjct: 2590 SEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDG 2626
Score = 45.4 bits (106), Expect = 9e-05
Identities = 59/246 (23%), Positives = 98/246 (39%), Gaps = 43/246 (17%)
Query: 51 REEEELDPR-----IQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQ--- 102
REE +D + IQEEL+ L Q+SE Q + + EA R ++E R + Q
Sbjct: 1382 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1441
Query: 103 -----GSHLGSC-----------IEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNA 146
G G +K + EA RL ++ Q E+Q+ +R + A
Sbjct: 1442 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQR-----KRQAEVELA 1496
Query: 147 AREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEA 206
+R AE +K R +E+ A E E RLR Q +Q +
Sbjct: 1497 SR---VKAEAEAAREKQRALQALEELRLQA-----EEAERRLR-----QAEVERARQVQV 1543
Query: 207 RVQALQKTLRRAIGKSRPYF-ELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLE 265
++ Q++ + R F E AQ + L+E V +L ++ + + + A R E
Sbjct: 1544 ALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERARE 1603
Query: 266 QISEQI 271
+ ++
Sbjct: 1604 EAEREL 1609
Score = 43.9 bits (102), Expect = 3e-04
Identities = 65/254 (25%), Positives = 107/254 (42%), Gaps = 41/254 (16%)
Query: 33 AEEPGGGGSSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRR-I 91
AE + EA++ E R EE E L Q++EE Q Q A R+
Sbjct: 2061 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2120
Query: 92 LQESARKLNTQGSHL------GSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHN 145
QE+AR+ + + L + +EK + + E + L ++AQ E + LR + + H
Sbjct: 2121 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAE-QTLRQKAQVEQELTTLRLQLEETDH- 2178
Query: 146 AAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAE 205
KN LD Q + AT EA +R + E E V R+ +
Sbjct: 2179 ---------------QKNLLDEELQRLKAEAT----EAARQRSQVEEELFSV-RVQMEEL 2218
Query: 206 ARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALR--- 262
++++A + RA+ K + L+E K+ +QVA+ R SVA +
Sbjct: 2219 SKLKARIEAENRAL-----ILRDKDNTQRFLQEEAEKM----KQVAEEAARLSVAAQEAA 2269
Query: 263 NLEQISEQIHARRR 276
L Q++E+ A++R
Sbjct: 2270 RLRQLAEEDLAQQR 2283
Score = 43.9 bits (102), Expect = 3e-04
Identities = 61/260 (23%), Positives = 110/260 (42%), Gaps = 37/260 (14%)
Query: 18 LRPEVVEDEVPRSPVAEEPGGGGSSSSEA--KLSPREEEELDPRIQ-EELEHLNQASEEI 74
LR ++ E + ++ + EE + ++EA + S EEE R+Q EEL L E
Sbjct: 2169 LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2228
Query: 75 NQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKE--AQQETQK 132
N+ + D+ T +R LQE A K+ A+ R+LA+E AQQ
Sbjct: 2229 NRALILRDKDNT--QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALA 2286
Query: 133 AALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGER 192
+ E+ ++ A R AE ++ + L + + RL+ ++
Sbjct: 2287 EKMLKEKMQAVQEATR---LKAEAELLQQQKELA---------------QEQARRLQEDK 2328
Query: 193 EHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQ 252
E ++ QQ Q Q+TL + + E+ A+ ++ K +V E+ + A+
Sbjct: 2329 E-----QMAQQLAEETQGFQRTLE---AERQRQLEMSAEAERL----KLRVAEMSRAQAR 2376
Query: 253 AKTRYSVALRNLEQISEQIH 272
A+ + E+I E++H
Sbjct: 2377 AEEDAQRFRKQAEEIGEKLH 2396
Score = 42.7 bits (99), Expect = 6e-04
Identities = 66/289 (22%), Positives = 103/289 (35%), Gaps = 51/289 (17%)
Query: 15 QGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKL------SPREEEELDPRIQEELEHLN 68
+ E + EDE + EE + E +L S E E +++ L
Sbjct: 1840 ENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR 1899
Query: 69 QASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSC----IEKARPYY---EARR 121
Q EEI ++ ++A + E R + L S +E AR E R
Sbjct: 1900 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 1959
Query: 122 LAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVN 181
+EA++ QK+ E A AA E V KV
Sbjct: 1960 RRREAEERVQKSLAAEEEAARQRKAALEEV----------------------ERLKAKVE 1997
Query: 182 EAEEERLRGEREHQRVTRLCQQ-AEARVQALQKTLRRAIGKSRPYFELKAQFSQIL---- 236
EA R R E+E R +L Q+ A+ R+QA +K A+ + + Q Q +
Sbjct: 1998 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2057
Query: 237 -----------EEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQIHAR 274
EE + + E++ AQ++ + A R + EQ AR
Sbjct: 2058 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQAR 2106
Score = 42.4 bits (98), Expect = 7e-04
Identities = 57/270 (21%), Positives = 104/270 (38%), Gaps = 44/270 (16%)
Query: 45 EAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQG- 103
+A+L P P++Q E + Q ++ +L + Y + + E+ R++ +
Sbjct: 1268 KAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEER 1327
Query: 104 -------------SHLGSCIEKARPYYE--------ARRLAKEAQQETQKAALRYERAV- 141
+ + + +EK R E A R AKE QQ Q+ +R E A
Sbjct: 1328 LAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAV 1387
Query: 142 ---------------SMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEE 186
++ E+ A Q A+++RL +E + ++ E +
Sbjct: 1388 DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRL--RIEEEIRVVRLQLEATERQ 1445
Query: 187 RLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTEL 246
R E E Q + ++AEA+ + Q+ R R + ++Q + E A +
Sbjct: 1446 RGGAEGELQALRARAEEAEAQKRQAQEEAERL----RRQVQDESQRKRQAEVELASRVKA 1501
Query: 247 EQQVAQAKTRYSVALRNLEQISEQIHARRR 276
E + A+ K R AL L +E+ R R
Sbjct: 1502 EAEAAREKQRALQALEELRLQAEEAERRLR 1531
Score = 38.5 bits (88), Expect = 0.011
Identities = 65/271 (23%), Positives = 108/271 (39%), Gaps = 33/271 (12%)
Query: 34 EEPGGGGSSSSEAKLSPREEEELDPR-IQEELEHLNQ----ASEEINQVELQL------- 81
E GG +A + EE E R QEE E L + S+ Q E++L
Sbjct: 1443 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1502
Query: 82 DEARTTYRRILQESARKLNTQGSHL-----GSCIEKARPYYEARRLAK---EAQQETQKA 133
EA +R LQ + +L Q + +E+AR A A+ EA+ ++++A
Sbjct: 1503 AEAAREKQRALQ-ALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRA 1561
Query: 134 ALRYERAVSMHNAAREMVFVAE--------QGVMADKNRLDPTWQEMLNHATCKVNEAEE 185
+ + A + E V VA+ A+ R + L K NEA
Sbjct: 1562 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1621
Query: 186 ERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTE 245
RL+ E Q+ + +AE + + ++ RR GK+ E + ++ E+ K +
Sbjct: 1622 LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR-GKAE---EQAVRQRELAEQELEKQRQ 1677
Query: 246 LEQQVAQAKTRYSVALRNLEQISEQIHARRR 276
L + AQ + L L +EQ +R+
Sbjct: 1678 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1708
Score = 36.6 bits (83), Expect = 0.040
Identities = 59/266 (22%), Positives = 106/266 (39%), Gaps = 39/266 (14%)
Query: 5 RQVPGGRETPQGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKLSPREEEELDPRIQEEL 64
RQV ET Q E+ + R+ AE+ +++ + S +EE +++EE
Sbjct: 1539 RQVQVALETAQRSAEAEL---QSKRASFAEK-------TAQLERSLQEEHVAVAQLREEA 1588
Query: 65 EHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRLAK 124
E Q E + + + ++ E+ R L Q + +K+ EA + +
Sbjct: 1589 ERRAQQQAEAERAREEAERELERWQLKANEALR-LRLQAEEVAQ--QKSLAQAEAEKQKE 1645
Query: 125 EAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAE 184
EA++E ++ E+AV +AEQ + + + T Q+
Sbjct: 1646 EAEREARRRGKAEEQAVRQRE-------LAEQELEKQRQLAEGTAQQ------------- 1685
Query: 185 EERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVT 244
RL E+E R+ +Q E + Q L++ L R ++ Q Q LE AKV
Sbjct: 1686 --RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREA----AAATQKRQELEAELAKVR 1739
Query: 245 ELEQQVAQAKTRYSVALRNLEQISEQ 270
+ + +K R R+ + S+Q
Sbjct: 1740 AEMEVLLASKARAEEESRSTSEKSKQ 1765
Score = 35.4 bits (80), Expect = 0.090
Identities = 46/192 (23%), Positives = 77/192 (40%), Gaps = 19/192 (9%)
Query: 29 RSPVAEEPGGGGSSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTY 88
R +AE EAKL + EE+ QE+ L Q ++ + Q L ++
Sbjct: 2427 REAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQ---LLQETQALQQSFLSEKDSLLQR 2483
Query: 89 RRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAR 148
R +++ KL E A+ A++L +E Q++ Q+ +R V+ AR
Sbjct: 2484 ERFIEQEKAKLEQLFQD-----EVAK----AQQLREEQQRQQQQMEQERQRLVASMEEAR 2534
Query: 149 EMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRG-----EREHQRVTRLCQQ 203
AE+GV + L Q+ ++ E +RLR E +H+ ++
Sbjct: 2535 RRQHEAEEGVRRKQEELQQLEQQRRQQE--ELLAEENQRLREQLQLLEEQHRAALAHSEE 2592
Query: 204 AEARVQALQKTL 215
A A KTL
Sbjct: 2593 VTASQVAATKTL 2604
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 49.3 bits (116), Expect = 6e-06
Identities = 57/233 (24%), Positives = 99/233 (42%), Gaps = 25/233 (10%)
Query: 51 REEEELDPRIQEELEHLNQAS-------EEINQVELQLDEARTTYRRILQESARKLN--T 101
R E + R+Q+ L +A+ EE+ +++ +++EAR R QESAR+L
Sbjct: 1967 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2026
Query: 102 QGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQG-VMA 160
+ + E+ + ++ +E QQ Q+ ++ AAR AE+ V A
Sbjct: 2027 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2086
Query: 161 DKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEA---RVQALQKTLRR 217
++ A + E ERL+ E Q R QA A R +A Q+ RR
Sbjct: 2087 EREA-----------AQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARR 2135
Query: 218 AIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQ 270
A + + +A ++ +E+HK + +Q AQ + + LE+ Q
Sbjct: 2136 AQAEQAALRQKQAADAE-MEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQ 2187
Score = 48.5 bits (114), Expect = 1e-05
Identities = 57/277 (20%), Positives = 114/277 (41%), Gaps = 21/277 (7%)
Query: 41 SSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLN 100
+ + KL E R +E+ + + +EEI + +L E T + L ++
Sbjct: 2366 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGE-KLHRTELATQEKVTLVQTLEIQR 2424
Query: 101 TQGSHLGSCI---------EKARPYYEAR--RLAKEAQQETQKAALRYERAVSMHN--AA 147
Q H + EK + EA+ +L E Q Q+ L E + +
Sbjct: 2425 QQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSE 2484
Query: 148 REMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEAR 207
++ + E+ + +K +L+ +Q+ + A E + ++ + E+E QR+ ++A R
Sbjct: 2485 KDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRR 2544
Query: 208 VQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQI 267
++ +RR + + + + Q ++L E + L +Q+ + ++ AL +
Sbjct: 2545 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR---LREQLQLLEEQHRAALAH---- 2597
Query: 268 SEQIHARRRGGLPPHPLGPRRSSPVGAEAGPEDMEDG 304
SE++ A + P G AEA PE DG
Sbjct: 2598 SEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDG 2634
Score = 45.4 bits (106), Expect = 9e-05
Identities = 59/246 (23%), Positives = 98/246 (39%), Gaps = 43/246 (17%)
Query: 51 REEEELDPR-----IQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQ--- 102
REE +D + IQEEL+ L Q+SE Q + + EA R ++E R + Q
Sbjct: 1390 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1449
Query: 103 -----GSHLGSC-----------IEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNA 146
G G +K + EA RL ++ Q E+Q+ +R + A
Sbjct: 1450 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQR-----KRQAEVELA 1504
Query: 147 AREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEA 206
+R AE +K R +E+ A E E RLR Q +Q +
Sbjct: 1505 SR---VKAEAEAAREKQRALQALEELRLQA-----EEAERRLR-----QAEVERARQVQV 1551
Query: 207 RVQALQKTLRRAIGKSRPYF-ELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLE 265
++ Q++ + R F E AQ + L+E V +L ++ + + + A R E
Sbjct: 1552 ALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERARE 1611
Query: 266 QISEQI 271
+ ++
Sbjct: 1612 EAEREL 1617
Score = 43.9 bits (102), Expect = 3e-04
Identities = 65/254 (25%), Positives = 107/254 (42%), Gaps = 41/254 (16%)
Query: 33 AEEPGGGGSSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRR-I 91
AE + EA++ E R EE E L Q++EE Q Q A R+
Sbjct: 2069 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2128
Query: 92 LQESARKLNTQGSHL------GSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHN 145
QE+AR+ + + L + +EK + + E + L ++AQ E + LR + + H
Sbjct: 2129 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAE-QTLRQKAQVEQELTTLRLQLEETDH- 2186
Query: 146 AAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAE 205
KN LD Q + AT EA +R + E E V R+ +
Sbjct: 2187 ---------------QKNLLDEELQRLKAEAT----EAARQRSQVEEELFSV-RVQMEEL 2226
Query: 206 ARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALR--- 262
++++A + RA+ K + L+E K+ +QVA+ R SVA +
Sbjct: 2227 SKLKARIEAENRAL-----ILRDKDNTQRFLQEEAEKM----KQVAEEAARLSVAAQEAA 2277
Query: 263 NLEQISEQIHARRR 276
L Q++E+ A++R
Sbjct: 2278 RLRQLAEEDLAQQR 2291
Score = 43.9 bits (102), Expect = 3e-04
Identities = 61/260 (23%), Positives = 110/260 (42%), Gaps = 37/260 (14%)
Query: 18 LRPEVVEDEVPRSPVAEEPGGGGSSSSEA--KLSPREEEELDPRIQ-EELEHLNQASEEI 74
LR ++ E + ++ + EE + ++EA + S EEE R+Q EEL L E
Sbjct: 2177 LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2236
Query: 75 NQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKE--AQQETQK 132
N+ + D+ T +R LQE A K+ A+ R+LA+E AQQ
Sbjct: 2237 NRALILRDKDNT--QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALA 2294
Query: 133 AALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGER 192
+ E+ ++ A R AE ++ + L + + RL+ ++
Sbjct: 2295 EKMLKEKMQAVQEATR---LKAEAELLQQQKELA---------------QEQARRLQEDK 2336
Query: 193 EHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQ 252
E ++ QQ Q Q+TL + + E+ A+ ++ K +V E+ + A+
Sbjct: 2337 E-----QMAQQLAEETQGFQRTLE---AERQRQLEMSAEAERL----KLRVAEMSRAQAR 2384
Query: 253 AKTRYSVALRNLEQISEQIH 272
A+ + E+I E++H
Sbjct: 2385 AEEDAQRFRKQAEEIGEKLH 2404
Score = 42.7 bits (99), Expect = 6e-04
Identities = 66/289 (22%), Positives = 103/289 (35%), Gaps = 51/289 (17%)
Query: 15 QGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKL------SPREEEELDPRIQEELEHLN 68
+ E + EDE + EE + E +L S E E +++ L
Sbjct: 1848 ENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR 1907
Query: 69 QASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSC----IEKARPYY---EARR 121
Q EEI ++ ++A + E R + L S +E AR E R
Sbjct: 1908 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 1967
Query: 122 LAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVN 181
+EA++ QK+ E A AA E V KV
Sbjct: 1968 RRREAEERVQKSLAAEEEAARQRKAALEEV----------------------ERLKAKVE 2005
Query: 182 EAEEERLRGEREHQRVTRLCQQ-AEARVQALQKTLRRAIGKSRPYFELKAQFSQIL---- 236
EA R R E+E R +L Q+ A+ R+QA +K A+ + + Q Q +
Sbjct: 2006 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2065
Query: 237 -----------EEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQIHAR 274
EE + + E++ AQ++ + A R + EQ AR
Sbjct: 2066 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQAR 2114
Score = 42.4 bits (98), Expect = 7e-04
Identities = 57/270 (21%), Positives = 104/270 (38%), Gaps = 44/270 (16%)
Query: 45 EAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQG- 103
+A+L P P++Q E + Q ++ +L + Y + + E+ R++ +
Sbjct: 1276 KAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEER 1335
Query: 104 -------------SHLGSCIEKARPYYE--------ARRLAKEAQQETQKAALRYERAV- 141
+ + + +EK R E A R AKE QQ Q+ +R E A
Sbjct: 1336 LAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAV 1395
Query: 142 ---------------SMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEE 186
++ E+ A Q A+++RL +E + ++ E +
Sbjct: 1396 DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRL--RIEEEIRVVRLQLEATERQ 1453
Query: 187 RLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTEL 246
R E E Q + ++AEA+ + Q+ R R + ++Q + E A +
Sbjct: 1454 RGGAEGELQALRARAEEAEAQKRQAQEEAERL----RRQVQDESQRKRQAEVELASRVKA 1509
Query: 247 EQQVAQAKTRYSVALRNLEQISEQIHARRR 276
E + A+ K R AL L +E+ R R
Sbjct: 1510 EAEAAREKQRALQALEELRLQAEEAERRLR 1539
Score = 38.5 bits (88), Expect = 0.011
Identities = 65/271 (23%), Positives = 108/271 (39%), Gaps = 33/271 (12%)
Query: 34 EEPGGGGSSSSEAKLSPREEEELDPR-IQEELEHLNQ----ASEEINQVELQL------- 81
E GG +A + EE E R QEE E L + S+ Q E++L
Sbjct: 1451 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1510
Query: 82 DEARTTYRRILQESARKLNTQGSHL-----GSCIEKARPYYEARRLAK---EAQQETQKA 133
EA +R LQ + +L Q + +E+AR A A+ EA+ ++++A
Sbjct: 1511 AEAAREKQRALQ-ALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRA 1569
Query: 134 ALRYERAVSMHNAAREMVFVAE--------QGVMADKNRLDPTWQEMLNHATCKVNEAEE 185
+ + A + E V VA+ A+ R + L K NEA
Sbjct: 1570 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1629
Query: 186 ERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTE 245
RL+ E Q+ + +AE + + ++ RR GK+ E + ++ E+ K +
Sbjct: 1630 LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR-GKAE---EQAVRQRELAEQELEKQRQ 1685
Query: 246 LEQQVAQAKTRYSVALRNLEQISEQIHARRR 276
L + AQ + L L +EQ +R+
Sbjct: 1686 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1716
Score = 36.6 bits (83), Expect = 0.040
Identities = 59/266 (22%), Positives = 106/266 (39%), Gaps = 39/266 (14%)
Query: 5 RQVPGGRETPQGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKLSPREEEELDPRIQEEL 64
RQV ET Q E+ + R+ AE+ +++ + S +EE +++EE
Sbjct: 1547 RQVQVALETAQRSAEAEL---QSKRASFAEK-------TAQLERSLQEEHVAVAQLREEA 1596
Query: 65 EHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRLAK 124
E Q E + + + ++ E+ R L Q + +K+ EA + +
Sbjct: 1597 ERRAQQQAEAERAREEAERELERWQLKANEALR-LRLQAEEVAQ--QKSLAQAEAEKQKE 1653
Query: 125 EAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAE 184
EA++E ++ E+AV +AEQ + + + T Q+
Sbjct: 1654 EAEREARRRGKAEEQAVRQRE-------LAEQELEKQRQLAEGTAQQ------------- 1693
Query: 185 EERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVT 244
RL E+E R+ +Q E + Q L++ L R ++ Q Q LE AKV
Sbjct: 1694 --RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREA----AAATQKRQELEAELAKVR 1747
Query: 245 ELEQQVAQAKTRYSVALRNLEQISEQ 270
+ + +K R R+ + S+Q
Sbjct: 1748 AEMEVLLASKARAEEESRSTSEKSKQ 1773
Score = 35.4 bits (80), Expect = 0.090
Identities = 46/192 (23%), Positives = 77/192 (40%), Gaps = 19/192 (9%)
Query: 29 RSPVAEEPGGGGSSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTY 88
R +AE EAKL + EE+ QE+ L Q ++ + Q L ++
Sbjct: 2435 REAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQ---LLQETQALQQSFLSEKDSLLQR 2491
Query: 89 RRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAR 148
R +++ KL E A+ A++L +E Q++ Q+ +R V+ AR
Sbjct: 2492 ERFIEQEKAKLEQLFQD-----EVAK----AQQLREEQQRQQQQMEQERQRLVASMEEAR 2542
Query: 149 EMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRG-----EREHQRVTRLCQQ 203
AE+GV + L Q+ ++ E +RLR E +H+ ++
Sbjct: 2543 RRQHEAEEGVRRKQEELQQLEQQRRQQE--ELLAEENQRLREQLQLLEEQHRAALAHSEE 2600
Query: 204 AEARVQALQKTL 215
A A KTL
Sbjct: 2601 VTASQVAATKTL 2612
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 49.3 bits (116), Expect = 6e-06
Identities = 57/233 (24%), Positives = 99/233 (42%), Gaps = 25/233 (10%)
Query: 51 REEEELDPRIQEELEHLNQAS-------EEINQVELQLDEARTTYRRILQESARKLN--T 101
R E + R+Q+ L +A+ EE+ +++ +++EAR R QESAR+L
Sbjct: 2008 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2067
Query: 102 QGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQG-VMA 160
+ + E+ + ++ +E QQ Q+ ++ AAR AE+ V A
Sbjct: 2068 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2127
Query: 161 DKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEA---RVQALQKTLRR 217
++ A + E ERL+ E Q R QA A R +A Q+ RR
Sbjct: 2128 EREA-----------AQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARR 2176
Query: 218 AIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQ 270
A + + +A ++ +E+HK + +Q AQ + + LE+ Q
Sbjct: 2177 AQAEQAALRQKQAADAE-MEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQ 2228
Score = 48.5 bits (114), Expect = 1e-05
Identities = 57/277 (20%), Positives = 114/277 (41%), Gaps = 21/277 (7%)
Query: 41 SSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLN 100
+ + KL E R +E+ + + +EEI + +L E T + L ++
Sbjct: 2407 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGE-KLHRTELATQEKVTLVQTLEIQR 2465
Query: 101 TQGSHLGSCI---------EKARPYYEAR--RLAKEAQQETQKAALRYERAVSMHN--AA 147
Q H + EK + EA+ +L E Q Q+ L E + +
Sbjct: 2466 QQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSE 2525
Query: 148 REMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEAR 207
++ + E+ + +K +L+ +Q+ + A E + ++ + E+E QR+ ++A R
Sbjct: 2526 KDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRR 2585
Query: 208 VQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQI 267
++ +RR + + + + Q ++L E + L +Q+ + ++ AL +
Sbjct: 2586 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR---LREQLQLLEEQHRAALAH---- 2638
Query: 268 SEQIHARRRGGLPPHPLGPRRSSPVGAEAGPEDMEDG 304
SE++ A + P G AEA PE DG
Sbjct: 2639 SEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDG 2675
Score = 45.4 bits (106), Expect = 9e-05
Identities = 59/246 (23%), Positives = 98/246 (39%), Gaps = 43/246 (17%)
Query: 51 REEEELDPR-----IQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQ--- 102
REE +D + IQEEL+ L Q+SE Q + + EA R ++E R + Q
Sbjct: 1431 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1490
Query: 103 -----GSHLGSC-----------IEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNA 146
G G +K + EA RL ++ Q E+Q+ +R + A
Sbjct: 1491 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQR-----KRQAEVELA 1545
Query: 147 AREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEA 206
+R AE +K R +E+ A E E RLR Q +Q +
Sbjct: 1546 SR---VKAEAEAAREKQRALQALEELRLQA-----EEAERRLR-----QAEVERARQVQV 1592
Query: 207 RVQALQKTLRRAIGKSRPYF-ELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLE 265
++ Q++ + R F E AQ + L+E V +L ++ + + + A R E
Sbjct: 1593 ALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERARE 1652
Query: 266 QISEQI 271
+ ++
Sbjct: 1653 EAEREL 1658
Score = 43.9 bits (102), Expect = 3e-04
Identities = 65/254 (25%), Positives = 107/254 (42%), Gaps = 41/254 (16%)
Query: 33 AEEPGGGGSSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRR-I 91
AE + EA++ E R EE E L Q++EE Q Q A R+
Sbjct: 2110 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2169
Query: 92 LQESARKLNTQGSHL------GSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHN 145
QE+AR+ + + L + +EK + + E + L ++AQ E + LR + + H
Sbjct: 2170 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAE-QTLRQKAQVEQELTTLRLQLEETDH- 2227
Query: 146 AAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAE 205
KN LD Q + AT EA +R + E E V R+ +
Sbjct: 2228 ---------------QKNLLDEELQRLKAEAT----EAARQRSQVEEELFSV-RVQMEEL 2267
Query: 206 ARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALR--- 262
++++A + RA+ K + L+E K+ +QVA+ R SVA +
Sbjct: 2268 SKLKARIEAENRAL-----ILRDKDNTQRFLQEEAEKM----KQVAEEAARLSVAAQEAA 2318
Query: 263 NLEQISEQIHARRR 276
L Q++E+ A++R
Sbjct: 2319 RLRQLAEEDLAQQR 2332
Score = 43.9 bits (102), Expect = 3e-04
Identities = 61/260 (23%), Positives = 110/260 (42%), Gaps = 37/260 (14%)
Query: 18 LRPEVVEDEVPRSPVAEEPGGGGSSSSEA--KLSPREEEELDPRIQ-EELEHLNQASEEI 74
LR ++ E + ++ + EE + ++EA + S EEE R+Q EEL L E
Sbjct: 2218 LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2277
Query: 75 NQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKE--AQQETQK 132
N+ + D+ T +R LQE A K+ A+ R+LA+E AQQ
Sbjct: 2278 NRALILRDKDNT--QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALA 2335
Query: 133 AALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGER 192
+ E+ ++ A R AE ++ + L + + RL+ ++
Sbjct: 2336 EKMLKEKMQAVQEATR---LKAEAELLQQQKELA---------------QEQARRLQEDK 2377
Query: 193 EHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQ 252
E ++ QQ Q Q+TL + + E+ A+ ++ K +V E+ + A+
Sbjct: 2378 E-----QMAQQLAEETQGFQRTLE---AERQRQLEMSAEAERL----KLRVAEMSRAQAR 2425
Query: 253 AKTRYSVALRNLEQISEQIH 272
A+ + E+I E++H
Sbjct: 2426 AEEDAQRFRKQAEEIGEKLH 2445
Score = 42.7 bits (99), Expect = 6e-04
Identities = 66/289 (22%), Positives = 103/289 (35%), Gaps = 51/289 (17%)
Query: 15 QGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKL------SPREEEELDPRIQEELEHLN 68
+ E + EDE + EE + E +L S E E +++ L
Sbjct: 1889 ENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR 1948
Query: 69 QASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSC----IEKARPYY---EARR 121
Q EEI ++ ++A + E R + L S +E AR E R
Sbjct: 1949 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 2008
Query: 122 LAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVN 181
+EA++ QK+ E A AA E V KV
Sbjct: 2009 RRREAEERVQKSLAAEEEAARQRKAALEEV----------------------ERLKAKVE 2046
Query: 182 EAEEERLRGEREHQRVTRLCQQ-AEARVQALQKTLRRAIGKSRPYFELKAQFSQIL---- 236
EA R R E+E R +L Q+ A+ R+QA +K A+ + + Q Q +
Sbjct: 2047 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2106
Query: 237 -----------EEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQIHAR 274
EE + + E++ AQ++ + A R + EQ AR
Sbjct: 2107 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQAR 2155
Score = 42.4 bits (98), Expect = 7e-04
Identities = 57/270 (21%), Positives = 104/270 (38%), Gaps = 44/270 (16%)
Query: 45 EAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQG- 103
+A+L P P++Q E + Q ++ +L + Y + + E+ R++ +
Sbjct: 1317 KAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEER 1376
Query: 104 -------------SHLGSCIEKARPYYE--------ARRLAKEAQQETQKAALRYERAV- 141
+ + + +EK R E A R AKE QQ Q+ +R E A
Sbjct: 1377 LAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAV 1436
Query: 142 ---------------SMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEE 186
++ E+ A Q A+++RL +E + ++ E +
Sbjct: 1437 DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRL--RIEEEIRVVRLQLEATERQ 1494
Query: 187 RLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTEL 246
R E E Q + ++AEA+ + Q+ R R + ++Q + E A +
Sbjct: 1495 RGGAEGELQALRARAEEAEAQKRQAQEEAERL----RRQVQDESQRKRQAEVELASRVKA 1550
Query: 247 EQQVAQAKTRYSVALRNLEQISEQIHARRR 276
E + A+ K R AL L +E+ R R
Sbjct: 1551 EAEAAREKQRALQALEELRLQAEEAERRLR 1580
Score = 38.5 bits (88), Expect = 0.011
Identities = 65/271 (23%), Positives = 108/271 (39%), Gaps = 33/271 (12%)
Query: 34 EEPGGGGSSSSEAKLSPREEEELDPR-IQEELEHLNQ----ASEEINQVELQL------- 81
E GG +A + EE E R QEE E L + S+ Q E++L
Sbjct: 1492 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1551
Query: 82 DEARTTYRRILQESARKLNTQGSHL-----GSCIEKARPYYEARRLAK---EAQQETQKA 133
EA +R LQ + +L Q + +E+AR A A+ EA+ ++++A
Sbjct: 1552 AEAAREKQRALQ-ALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRA 1610
Query: 134 ALRYERAVSMHNAAREMVFVAE--------QGVMADKNRLDPTWQEMLNHATCKVNEAEE 185
+ + A + E V VA+ A+ R + L K NEA
Sbjct: 1611 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1670
Query: 186 ERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTE 245
RL+ E Q+ + +AE + + ++ RR GK+ E + ++ E+ K +
Sbjct: 1671 LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR-GKAE---EQAVRQRELAEQELEKQRQ 1726
Query: 246 LEQQVAQAKTRYSVALRNLEQISEQIHARRR 276
L + AQ + L L +EQ +R+
Sbjct: 1727 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1757
Score = 36.6 bits (83), Expect = 0.040
Identities = 59/266 (22%), Positives = 106/266 (39%), Gaps = 39/266 (14%)
Query: 5 RQVPGGRETPQGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKLSPREEEELDPRIQEEL 64
RQV ET Q E+ + R+ AE+ +++ + S +EE +++EE
Sbjct: 1588 RQVQVALETAQRSAEAEL---QSKRASFAEK-------TAQLERSLQEEHVAVAQLREEA 1637
Query: 65 EHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRLAK 124
E Q E + + + ++ E+ R L Q + +K+ EA + +
Sbjct: 1638 ERRAQQQAEAERAREEAERELERWQLKANEALR-LRLQAEEVAQ--QKSLAQAEAEKQKE 1694
Query: 125 EAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAE 184
EA++E ++ E+AV +AEQ + + + T Q+
Sbjct: 1695 EAEREARRRGKAEEQAVRQRE-------LAEQELEKQRQLAEGTAQQ------------- 1734
Query: 185 EERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVT 244
RL E+E R+ +Q E + Q L++ L R ++ Q Q LE AKV
Sbjct: 1735 --RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREA----AAATQKRQELEAELAKVR 1788
Query: 245 ELEQQVAQAKTRYSVALRNLEQISEQ 270
+ + +K R R+ + S+Q
Sbjct: 1789 AEMEVLLASKARAEEESRSTSEKSKQ 1814
Score = 35.4 bits (80), Expect = 0.090
Identities = 46/192 (23%), Positives = 77/192 (40%), Gaps = 19/192 (9%)
Query: 29 RSPVAEEPGGGGSSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTY 88
R +AE EAKL + EE+ QE+ L Q ++ + Q L ++
Sbjct: 2476 REAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQ---LLQETQALQQSFLSEKDSLLQR 2532
Query: 89 RRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAR 148
R +++ KL E A+ A++L +E Q++ Q+ +R V+ AR
Sbjct: 2533 ERFIEQEKAKLEQLFQD-----EVAK----AQQLREEQQRQQQQMEQERQRLVASMEEAR 2583
Query: 149 EMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRG-----EREHQRVTRLCQQ 203
AE+GV + L Q+ ++ E +RLR E +H+ ++
Sbjct: 2584 RRQHEAEEGVRRKQEELQQLEQQRRQQE--ELLAEENQRLREQLQLLEEQHRAALAHSEE 2641
Query: 204 AEARVQALQKTL 215
A A KTL
Sbjct: 2642 VTASQVAATKTL 2653
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 48.9 bits (115), Expect = 8e-06
Identities = 48/230 (20%), Positives = 99/230 (43%), Gaps = 11/230 (4%)
Query: 52 EEEELDPRIQEELEHLNQAS-------EEINQVELQLDEARTTYRRILQESARKLNTQGS 104
EE+ L + E+ + L + + EE+ Q + +R + L E+ +LN S
Sbjct: 1708 EEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHS 1767
Query: 105 -HLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREMV--FVAEQGVMAD 161
+ G +K + + +L+ E ++ Q+ E+A A M EQ A
Sbjct: 1768 QNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAH 1827
Query: 162 KNRLDPTWQEMLNHATCKVNEAEEERLR-GEREHQRVTRLCQQAEARVQALQKTLRRAIG 220
R+ T ++ + ++ EAE+ LR G+++ Q++ ++ EA + A QK A+
Sbjct: 1828 LERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALK 1887
Query: 221 KSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQ 270
R + + + EE + + ++ V + +++ R E+ +Q
Sbjct: 1888 GVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQ 1937
Score = 42.7 bits (99), Expect = 6e-04
Identities = 55/243 (22%), Positives = 107/243 (44%), Gaps = 17/243 (6%)
Query: 41 SSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEA-RTTYRRILQESARKL 99
S S+ L +E+ L ++Q++++ L +EE+ + EL+ + A R + E+AR+L
Sbjct: 1134 SELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEE-ELEAERAARARVEKQRAEAAREL 1192
Query: 100 NTQGSHLGSCIEKARPYYEARRLAKEAQ-----QETQKAALRYERAVSMHNAAREMVFVA 154
L + E R +EA+ +E ++AALR+E V+ ++ A
Sbjct: 1193 EELSERLEEAGGASAGQREGCR-KREAELGRLRRELEEAALRHEATVAALRR-KQAEGAA 1250
Query: 155 EQGVMADK-NRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQ-------QAEA 206
E G D R+ ++ + +V++ R +LC+ +A+
Sbjct: 1251 ELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKI 1310
Query: 207 RVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQ 266
+V+ LQ+ L A + + S++LEE + +++L + A A R LE+
Sbjct: 1311 KVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEE 1370
Query: 267 ISE 269
S+
Sbjct: 1371 ESK 1373
Score = 40.0 bits (92), Expect = 0.004
Identities = 50/223 (22%), Positives = 105/223 (47%), Gaps = 35/223 (15%)
Query: 69 QASEEINQVELQLDEA-RTTYRRI---LQESARKLNTQGSHLGSCIEKARPYYE-ARRLA 123
QA+ + Q +L+ ++A R +R+ L E A+ L + S L + +E+ R E R
Sbjct: 1689 QAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSR 1748
Query: 124 KEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEA 183
+ A+QE +A ER +H+ G++ K +L+ ++ +V EA
Sbjct: 1749 RLAEQELLEAT---ERLNLLHSQ--------NTGLLNQKKKLEADLAQLSG----EVEEA 1793
Query: 184 EEERLRGEREHQR-VTRLCQQAE---------ARVQALQKTLRRAIGKSRPYFELKAQFS 233
+ER E + ++ +T AE A ++ ++KTL + + + + E Q +
Sbjct: 1794 AQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAA 1853
Query: 234 -----QILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQI 271
+ +++ +AKV ELE ++ + +++ AL+ + + ++
Sbjct: 1854 LRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRV 1896
Score = 36.2 bits (82), Expect = 0.053
Identities = 51/249 (20%), Positives = 100/249 (40%), Gaps = 34/249 (13%)
Query: 19 RPEVVEDEVPRSPVAEEPGGGGSSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVE 78
R E +E+ + + + G ++ AK S E+ +L R+Q E E + E
Sbjct: 1431 RTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKL--RLQTESEDVTLELERATSAA 1488
Query: 79 LQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYE 138
LD+ + R L+ E+ R E +R + AQ+E++
Sbjct: 1489 AALDKKQRHLERALE-----------------ERRRQEEEMQRELEAAQRESRGLGTELF 1531
Query: 139 RAVSMHNAARE-MVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRV 197
R H A E + + + + D T Q L+ + + E ++ L GE+ +
Sbjct: 1532 RLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEK--SEI 1589
Query: 198 TRLCQQAEARVQALQ-KTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTR 256
++AE ++ + KTLR ++ + SQ+ E K+ E +++ A +
Sbjct: 1590 QAALEEAEGALELEETKTLR-----------IQLELSQVKAEVDRKLAEKDEECANLRRN 1638
Query: 257 YSVALRNLE 265
+ A+ +L+
Sbjct: 1639 HQRAVESLQ 1647
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 48.1 bits (113), Expect = 1e-05
Identities = 63/287 (21%), Positives = 114/287 (39%), Gaps = 47/287 (16%)
Query: 2 AELRQVPGGRETPQGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKLSPREE-------- 53
AEL++V + + R + D + R+ EE +L EE
Sbjct: 1355 AELQRVLSKANSEVAQWRTKYETDAIQRTEELEE----AKKKLAQRLQEAEEAVEAVNAK 1410
Query: 54 ----EELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSC 109
E+ R+Q E+E L E N LD+ + + +IL E +K S L S
Sbjct: 1411 CSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESS 1470
Query: 110 IEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTW 169
++AR K A +E+ + ++R N E+ + EQ
Sbjct: 1471 QKEARSLSTELFKLKNAYEESLEHLETFKR--ENKNLQEEISDLTEQ------------- 1515
Query: 170 QEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELK 229
L + ++E E+ R + E E + ++AEA ++ + + RA +
Sbjct: 1516 ---LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRA----------Q 1562
Query: 230 AQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQIHARRR 276
+F+QI E + K+ E ++++ QAK + LR ++ + + A R
Sbjct: 1563 LEFNQIKAEIERKLAEKDEEMEQAKRNH---LRVVDSLQTSLDAETR 1606
Score = 30.0 bits (66), Expect = 3.8
Identities = 49/269 (18%), Positives = 101/269 (37%), Gaps = 34/269 (12%)
Query: 30 SPVAEEPGGGGSSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYR 89
S + E+ G G + E + ++ E +Q LE +A + E ++ A+ +
Sbjct: 1510 SDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALE---EAEASLEHEEGKILRAQLEFN 1566
Query: 90 RILQESARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAARE 149
+I E RKL + + ++ + + +A+ ++ ALR ++ + E
Sbjct: 1567 QIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEME 1626
Query: 150 MVFVAEQGVMADKNRLDPTWQEMLNHATCKVN-----------------------EAEEE 186
+ + A+ + + Q +L +++ +AE E
Sbjct: 1627 IQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE 1686
Query: 187 RLRGEREH-QRVTRLCQQ----AEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKA 241
LR E +R +L +Q RVQ L I + + ++ A SQ+ E +
Sbjct: 1687 ELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKK---KMDADLSQLQTEVEE 1743
Query: 242 KVTELEQQVAQAKTRYSVALRNLEQISEQ 270
V E +AK + A E++ ++
Sbjct: 1744 AVQECRNAEEKAKKAITDAAMMAEELKKE 1772
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 47.4 bits (111), Expect = 2e-05
Identities = 67/310 (21%), Positives = 127/310 (40%), Gaps = 44/310 (14%)
Query: 9 GGRETPQGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKLSPRE------EEELDPRIQE 62
GG E+ + E E + P+ P P G + E + RE E++ +P+ Q
Sbjct: 47 GGSESQEEEEPQE--RNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQP 104
Query: 63 ELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRL 122
+ E L Q + ELQ + +++ Q K Q H + + ++ ++L
Sbjct: 105 QHEQLQQPQPHL---ELQQQPQQDGQQQLSQLQQEK--HQSVHHQELKPELQLMHQQQQL 159
Query: 123 AKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNE 182
+ QE Q+ + E+ + EQ V+ + +L QE + +
Sbjct: 160 QPQQVQEQQRLQQQQEQLQTQQ--------AQEQQVLQQQEQLQQQVQEQ-QLLQQQQEQ 210
Query: 183 AEEERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAK 242
++++L ++E + + QQ E Q Q L + G+ + Q+L++ +A+
Sbjct: 211 LQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQ---------QQLLQQQQAQ 261
Query: 243 VTE--LEQQVAQAKTRYSVALRNLEQISEQIHAR---------RRGGLPPHPLGPRRSSP 291
+ + LEQQ QA+ + + L+ EQ+ +Q + ++ L P PL P
Sbjct: 262 LQQQLLEQQ--QAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEE 319
Query: 292 VGAEAGPEDM 301
V E P D+
Sbjct: 320 VELELMPVDL 329
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 47.4 bits (111), Expect = 2e-05
Identities = 53/233 (22%), Positives = 100/233 (42%), Gaps = 22/233 (9%)
Query: 47 KLSPREEEEL---DPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQG 103
+L+ ++EE++ + +IQE E + + E+I + E E ++ E K+ Q
Sbjct: 281 RLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQE----EKMRRQEEMMWEKEEKMRRQE 336
Query: 104 SHLGSCIEKARPYYEAR------RLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQG 157
+ EK R E R +E +QE +K + +R R+ + EQ
Sbjct: 337 EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ- 395
Query: 158 VMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLRR 217
+K R +EM+ K+ E EE+ E E Q ++ E +++ +K +R
Sbjct: 396 --EEKIREQ---EEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIRE 450
Query: 218 AIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQ 270
K R E+ + + + E + K+ E E ++ + + + R E+I EQ
Sbjct: 451 QEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMR---RQEEKIREQ 500
>gi|62243374 MAD1-like 1 protein [Homo sapiens]
Length = 718
Score = 47.4 bits (111), Expect = 2e-05
Identities = 59/250 (23%), Positives = 101/250 (40%), Gaps = 26/250 (10%)
Query: 35 EPGGGGSSSSEAKLSPREEEELDPRIQEELE------HLNQASEEINQVELQLDEARTTY 88
E G G S+ A S + + + +++E E HL Q E Q+EL AR
Sbjct: 26 EGGSGLDISTSAPGSLQMQYQQSMQLEERAEQIRSKSHLIQVEREKMQMELSHKRARVEL 85
Query: 89 RRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQE----TQKAALRYERAVSMH 144
R SAR + + + R E A+E QE ++ + A
Sbjct: 86 ERAASTSARNYEREVDRNQELLTRIRQLQEREAGAEEKMQEQLERNRQCQQNLDAASKRL 145
Query: 145 NAAREMVFVAEQGVMADKNRL-DPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQ 203
+ + A + + A K R+ + W M K E+E++ L+ + + Q + CQ+
Sbjct: 146 REKEDSLAQAGETINALKGRISELQWSVMDQEMRVKRLESEKQELQEQLDLQH--KKCQE 203
Query: 204 AEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYS--VAL 261
A ++Q LQ + E +A Q +++ + K++ EQ A K S V L
Sbjct: 204 ANQKIQELQASQ-----------EARADHEQQIKDLEQKLSLQEQDAAIVKNMKSELVRL 252
Query: 262 RNLEQISEQI 271
LE+ +Q+
Sbjct: 253 PRLERELKQL 262
Score = 28.9 bits (63), Expect = 8.4
Identities = 39/185 (21%), Positives = 75/185 (40%), Gaps = 36/185 (19%)
Query: 92 LQESARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREMV 151
L+E A ++ ++ SHL I+ R + K A+ E ++AA + S N RE+
Sbjct: 51 LEERAEQIRSK-SHL---IQVEREKMQMELSHKRARVELERAA-----STSARNYEREV- 100
Query: 152 FVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQAL 211
D+N QE+L ++ + +E E + Q +Q + + A
Sbjct: 101 ---------DRN------QELLT----RIRQLQEREAGAEEKMQEQLERNRQCQQNLDAA 141
Query: 212 QKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQI 271
K LR + AQ + + K +++EL+ V + R +++ EQ+
Sbjct: 142 SKRLREKE-------DSLAQAGETINALKGRISELQWSVMDQEMRVKRLESEKQELQEQL 194
Query: 272 HARRR 276
+ +
Sbjct: 195 DLQHK 199
>gi|62243369 MAD1-like 1 protein [Homo sapiens]
Length = 718
Score = 47.4 bits (111), Expect = 2e-05
Identities = 59/250 (23%), Positives = 101/250 (40%), Gaps = 26/250 (10%)
Query: 35 EPGGGGSSSSEAKLSPREEEELDPRIQEELE------HLNQASEEINQVELQLDEARTTY 88
E G G S+ A S + + + +++E E HL Q E Q+EL AR
Sbjct: 26 EGGSGLDISTSAPGSLQMQYQQSMQLEERAEQIRSKSHLIQVEREKMQMELSHKRARVEL 85
Query: 89 RRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQE----TQKAALRYERAVSMH 144
R SAR + + + R E A+E QE ++ + A
Sbjct: 86 ERAASTSARNYEREVDRNQELLTRIRQLQEREAGAEEKMQEQLERNRQCQQNLDAASKRL 145
Query: 145 NAAREMVFVAEQGVMADKNRL-DPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQ 203
+ + A + + A K R+ + W M K E+E++ L+ + + Q + CQ+
Sbjct: 146 REKEDSLAQAGETINALKGRISELQWSVMDQEMRVKRLESEKQELQEQLDLQH--KKCQE 203
Query: 204 AEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYS--VAL 261
A ++Q LQ + E +A Q +++ + K++ EQ A K S V L
Sbjct: 204 ANQKIQELQASQ-----------EARADHEQQIKDLEQKLSLQEQDAAIVKNMKSELVRL 252
Query: 262 RNLEQISEQI 271
LE+ +Q+
Sbjct: 253 PRLERELKQL 262
Score = 28.9 bits (63), Expect = 8.4
Identities = 39/185 (21%), Positives = 75/185 (40%), Gaps = 36/185 (19%)
Query: 92 LQESARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREMV 151
L+E A ++ ++ SHL I+ R + K A+ E ++AA + S N RE+
Sbjct: 51 LEERAEQIRSK-SHL---IQVEREKMQMELSHKRARVELERAA-----STSARNYEREV- 100
Query: 152 FVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQAL 211
D+N QE+L ++ + +E E + Q +Q + + A
Sbjct: 101 ---------DRN------QELLT----RIRQLQEREAGAEEKMQEQLERNRQCQQNLDAA 141
Query: 212 QKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQI 271
K LR + AQ + + K +++EL+ V + R +++ EQ+
Sbjct: 142 SKRLREKE-------DSLAQAGETINALKGRISELQWSVMDQEMRVKRLESEKQELQEQL 194
Query: 272 HARRR 276
+ +
Sbjct: 195 DLQHK 199
>gi|62243332 MAD1-like 1 protein [Homo sapiens]
Length = 718
Score = 47.4 bits (111), Expect = 2e-05
Identities = 59/250 (23%), Positives = 101/250 (40%), Gaps = 26/250 (10%)
Query: 35 EPGGGGSSSSEAKLSPREEEELDPRIQEELE------HLNQASEEINQVELQLDEARTTY 88
E G G S+ A S + + + +++E E HL Q E Q+EL AR
Sbjct: 26 EGGSGLDISTSAPGSLQMQYQQSMQLEERAEQIRSKSHLIQVEREKMQMELSHKRARVEL 85
Query: 89 RRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQE----TQKAALRYERAVSMH 144
R SAR + + + R E A+E QE ++ + A
Sbjct: 86 ERAASTSARNYEREVDRNQELLTRIRQLQEREAGAEEKMQEQLERNRQCQQNLDAASKRL 145
Query: 145 NAAREMVFVAEQGVMADKNRL-DPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQ 203
+ + A + + A K R+ + W M K E+E++ L+ + + Q + CQ+
Sbjct: 146 REKEDSLAQAGETINALKGRISELQWSVMDQEMRVKRLESEKQELQEQLDLQH--KKCQE 203
Query: 204 AEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYS--VAL 261
A ++Q LQ + E +A Q +++ + K++ EQ A K S V L
Sbjct: 204 ANQKIQELQASQ-----------EARADHEQQIKDLEQKLSLQEQDAAIVKNMKSELVRL 252
Query: 262 RNLEQISEQI 271
LE+ +Q+
Sbjct: 253 PRLERELKQL 262
Score = 28.9 bits (63), Expect = 8.4
Identities = 39/185 (21%), Positives = 75/185 (40%), Gaps = 36/185 (19%)
Query: 92 LQESARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREMV 151
L+E A ++ ++ SHL I+ R + K A+ E ++AA + S N RE+
Sbjct: 51 LEERAEQIRSK-SHL---IQVEREKMQMELSHKRARVELERAA-----STSARNYEREV- 100
Query: 152 FVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQAL 211
D+N QE+L ++ + +E E + Q +Q + + A
Sbjct: 101 ---------DRN------QELLT----RIRQLQEREAGAEEKMQEQLERNRQCQQNLDAA 141
Query: 212 QKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQI 271
K LR + AQ + + K +++EL+ V + R +++ EQ+
Sbjct: 142 SKRLREKE-------DSLAQAGETINALKGRISELQWSVMDQEMRVKRLESEKQELQEQL 194
Query: 272 HARRR 276
+ +
Sbjct: 195 DLQHK 199
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 47.4 bits (111), Expect = 2e-05
Identities = 62/276 (22%), Positives = 110/276 (39%), Gaps = 44/276 (15%)
Query: 2 AELRQVPGGRETPQGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKLSPREE-------- 53
AEL++V + + R + D + R+ EE +L EE
Sbjct: 1357 AELQRVLSKANSEVAQWRTKYETDAIQRTEELEE----AKKKLAQRLQDAEEAVEAVNAK 1412
Query: 54 ----EELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSC 109
E+ R+Q E+E L E N LD+ + + +IL E +K S L S
Sbjct: 1413 CSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESS 1472
Query: 110 IEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTW 169
++AR K A +E+ + ++R N E+ + EQ KN
Sbjct: 1473 QKEARSLSTELFKLKNAYEESLEHLETFKR--ENKNLQEEISDLTEQLGEGGKN------ 1524
Query: 170 QEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELK 229
V+E E+ R + E E + ++AEA ++ + + RA +
Sbjct: 1525 ----------VHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRA----------Q 1564
Query: 230 AQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLE 265
+F+QI E + K+ E ++++ QAK + + +L+
Sbjct: 1565 LEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQ 1600
Score = 31.6 bits (70), Expect = 1.3
Identities = 46/222 (20%), Positives = 89/222 (40%), Gaps = 32/222 (14%)
Query: 55 ELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKAR 114
ELD + +E + +A + +V L++ YR L+E+ R LN ++A+
Sbjct: 1229 ELDD-VTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLN------DFTTQRAK 1281
Query: 115 PYYEARRLAKEAQQE----TQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQ 170
E LA++ +++ +Q + M + R++ E+G KN L Q
Sbjct: 1282 LQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQL---EEEG--KAKNALAHALQ 1336
Query: 171 EMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKA 230
+ + EEE +A+A +Q + + + R +E A
Sbjct: 1337 SARHDCDLLREQYEEE---------------TEAKAELQRVLSKANSEVAQWRTKYETDA 1381
Query: 231 -QFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQI 271
Q ++ LEE K K+ + Q +A + +LE+ ++
Sbjct: 1382 IQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRL 1423
>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
Length = 1233
Score = 47.0 bits (110), Expect = 3e-05
Identities = 61/228 (26%), Positives = 94/228 (41%), Gaps = 26/228 (11%)
Query: 25 DEVPRSPVAEEPGGGGSSSSEAKLSPREE----------EELDPRIQEELEHLNQASEEI 74
+E R + EE G G EA+ +PREE E+ + R +EE E L +A EE
Sbjct: 262 EENRRQELLEEEGEGQEPPLEAERAPREEQQRSLEAPGWEDAERREREERERL-EAEEER 320
Query: 75 NQVELQLDEARTTYRRILQESAR--KLNTQGSHLGSCIE--KARPYYEARRLAKEAQQET 130
+++ Q A+ RR L+E AR + Q G C E K + EA + QQE
Sbjct: 321 RRLQAQ---AQAEERRRLEEDARLEERRRQEEEEGRCAEELKRQEEEEAEGWEELEQQEA 377
Query: 131 Q----KAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEE 186
+ AL E A E + E+ A E+LN ++ + E
Sbjct: 378 EVQGPPEALE-ETGEGRRGAEEEDLGEEEEEGQAHLEDWRGQLSELLNDFEERLEDQERL 436
Query: 187 RLRGEREHQRVTRLCQQAEARVQALQKTLRRA---IGKSRPYFELKAQ 231
+ G+REH +C++ + ++ R+ G RP E K +
Sbjct: 437 KPEGQREHSEEPGICEEQNPEAERRREQQGRSGDFQGADRPGPEEKRE 484
>gi|239756174 PREDICTED: hypothetical protein [Homo sapiens]
Length = 625
Score = 46.2 bits (108), Expect = 5e-05
Identities = 62/228 (27%), Positives = 102/228 (44%), Gaps = 14/228 (6%)
Query: 59 RIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYE 118
R QEEL L Q + Q ELQ A+ R +E R L + +E+ R
Sbjct: 363 RHQEELLLLEQRAAAHGQWELQRVHAKQRREREEREKQRALEQGRRAWAAQVEERR---- 418
Query: 119 ARRLAKEAQQETQKAALRYERAVSMHN--AAREMVFVAEQGVMADK-NRLDPTWQEM-LN 174
R +E ++ ++ +YER+ A R+ + E+ A + +RL QE L
Sbjct: 419 -GRRGREEREAARRRQRQYERSEERRRELAERQGLLRRERAERAAREDRLRKLQQEQNLK 477
Query: 175 HATCKVNEAEE--ERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQF 232
+ E E E++R ER QR R Q+ E ++Q ++ L RA ++R L+ +
Sbjct: 478 QREEGLQEGRERAEQIRRERA-QRAARAKQRQEGQLQREKRELSRA-ERARHEALLQGRT 535
Query: 233 SQILEEHKAKVTELEQQVAQAKTRYS-VALRNLEQISEQIHARRRGGL 279
Q +E + + LE + +A+ Y +A+ + SEQ+ RR L
Sbjct: 536 RQQRQEREGLRSSLEASLGRAQENYEHLAIGRKLERSEQLTRERRSAL 583
>gi|239750672 PREDICTED: hypothetical protein [Homo sapiens]
Length = 627
Score = 46.2 bits (108), Expect = 5e-05
Identities = 62/228 (27%), Positives = 102/228 (44%), Gaps = 14/228 (6%)
Query: 59 RIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYE 118
R QEEL L Q + Q ELQ A+ R +E R L + +E+ R
Sbjct: 365 RHQEELLLLEQRAAAHGQWELQRVHAKQRREREEREKQRALEQGRRAWAAQVEERR---- 420
Query: 119 ARRLAKEAQQETQKAALRYERAVSMHN--AAREMVFVAEQGVMADK-NRLDPTWQEM-LN 174
R +E ++ ++ +YER+ A R+ + E+ A + +RL QE L
Sbjct: 421 -GRRGREEREAARRRQRQYERSEERRRELAERQGLLRRERAERAAREDRLRKLQQEQNLK 479
Query: 175 HATCKVNEAEE--ERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQF 232
+ E E E++R ER QR R Q+ E ++Q ++ L RA ++R L+ +
Sbjct: 480 QREEGLQEGRERAEQIRRERA-QRAARAKQRQEGQLQREKRELSRA-ERARHEALLQGRT 537
Query: 233 SQILEEHKAKVTELEQQVAQAKTRYS-VALRNLEQISEQIHARRRGGL 279
Q +E + + LE + +A+ Y +A+ + SEQ+ RR L
Sbjct: 538 RQQRQEREGLRSSLEASLGRAQENYEHLAIGRKLERSEQLTRERRSAL 585
>gi|239744982 PREDICTED: hypothetical protein [Homo sapiens]
Length = 627
Score = 46.2 bits (108), Expect = 5e-05
Identities = 62/228 (27%), Positives = 102/228 (44%), Gaps = 14/228 (6%)
Query: 59 RIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYE 118
R QEEL L Q + Q ELQ A+ R +E R L + +E+ R
Sbjct: 365 RHQEELLLLEQRAAAHGQWELQRVHAKQRREREEREKQRALEQGRRAWAAQVEERR---- 420
Query: 119 ARRLAKEAQQETQKAALRYERAVSMHN--AAREMVFVAEQGVMADK-NRLDPTWQEM-LN 174
R +E ++ ++ +YER+ A R+ + E+ A + +RL QE L
Sbjct: 421 -GRRGREEREAARRRQRQYERSEERRRELAERQGLLRRERAERAAREDRLRKLQQEQNLK 479
Query: 175 HATCKVNEAEE--ERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQF 232
+ E E E++R ER QR R Q+ E ++Q ++ L RA ++R L+ +
Sbjct: 480 QREEGLQEGRERAEQIRRERA-QRAARAKQRQEGQLQREKRELSRA-ERARHEALLQGRT 537
Query: 233 SQILEEHKAKVTELEQQVAQAKTRYS-VALRNLEQISEQIHARRRGGL 279
Q +E + + LE + +A+ Y +A+ + SEQ+ RR L
Sbjct: 538 RQQRQEREGLRSSLEASLGRAQENYEHLAIGRKLERSEQLTRERRSAL 585
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 45.4 bits (106), Expect = 9e-05
Identities = 55/228 (24%), Positives = 94/228 (41%), Gaps = 17/228 (7%)
Query: 44 SEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQG 103
+E++ S +EE R + E L +A + E L E R + +A T
Sbjct: 1947 AESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTA----TLQ 2002
Query: 104 SHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAA-----REMVFVAEQGV 158
+ L +C +R EA R+ + E Q LRY+ V A E+ E+
Sbjct: 2003 ASLDACQAHSRQLEEALRIQ---EGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQ 2059
Query: 159 MADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLC-QQAEARVQALQKTLRR 217
+ +K+ + M+ E EEE +RG + R +L Q E + L++T +R
Sbjct: 2060 LLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQR 2119
Query: 218 AIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLE 265
++ P+ + + +EE K+ LE ++ + R ALR E
Sbjct: 2120 NNLEALPH----SHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTE 2163
Score = 43.1 bits (100), Expect = 4e-04
Identities = 52/227 (22%), Positives = 96/227 (42%), Gaps = 15/227 (6%)
Query: 52 EEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIE 111
++ L+ + E E + + + ELQ EA+ R +LQ + L Q HL + +
Sbjct: 1307 KQNSLESELMELHETMASLQSRLRRAELQRMEAQGE-RELLQAAKENLTAQVEHLQAAVV 1365
Query: 112 KARPYYEARRLAKEAQQETQKA-ALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQ 170
+AR A + +E + + A L+ E S A+ + EQG + K Q
Sbjct: 1366 EARAQASAAGILEEDLRTARSALKLKNEEVESERERAQAL---QEQGEL--KVAQGKALQ 1420
Query: 171 EMLNHATCKVNEAEE--ERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFEL 228
E L T + E EE E LRG+ + R Q+A + +L + K +L
Sbjct: 1421 ENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLD------LKKRNQEVDL 1474
Query: 229 KAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQIHARR 275
+ + Q LE+ ++ + L V + + + +V + ++ + +R
Sbjct: 1475 QQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQR 1521
Score = 42.4 bits (98), Expect = 7e-04
Identities = 44/194 (22%), Positives = 76/194 (39%), Gaps = 28/194 (14%)
Query: 47 KLSPREEEEL-----DPRIQEELEHLNQA-----------SEEINQVELQLDEARTTYRR 90
K SP EE+ L +PR+Q ELE L A E+ + L L + + +
Sbjct: 2130 KTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSS 2189
Query: 91 I------LQESARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMH 144
+ LQ S + +++ L +E R E RL T + R E+ V +
Sbjct: 2190 LQEVAMFLQASVLERDSEQQRLQDELELTRRALEKERLHSPGATSTAELGSRGEQGVQLG 2249
Query: 145 NAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQA 204
+ + G+ +W++ L H V E +R R +R + ++ +Q
Sbjct: 2250 EVSGVEAEPSPDGMEKQ------SWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQV 2303
Query: 205 EARVQALQKTLRRA 218
E + L++ RA
Sbjct: 2304 ERERRKLKREAMRA 2317
Score = 38.1 bits (87), Expect = 0.014
Identities = 59/272 (21%), Positives = 113/272 (41%), Gaps = 36/272 (13%)
Query: 52 EEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIE 111
E +EL +++++L+ L++ E + + Q ++ ++ LQE+ + + L S ++
Sbjct: 1747 ELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLD 1806
Query: 112 KARPYYEARRLAKEA-QQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQ 170
+A+ R EA QQE Q+A + ER +A + + EQ M K R
Sbjct: 1807 EAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGAL---EQAHMTLKER------ 1857
Query: 171 EMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSR----PYF 226
H + ++ + RL E + RVQAL++ L +SR
Sbjct: 1858 ----HGELQDHKEQARRLEEELAVE---------GRRVQALEEVLGDLRAESREQEKALL 1904
Query: 227 ELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQIHARRRGGLPPHPLGP 286
L+ Q ++ +EH+ + L+ QA+ + LE + + + R
Sbjct: 1905 ALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRH---------Q 1955
Query: 287 RRSSPVGAEAGPEDMEDGDSGIEGAEGAGLEE 318
++ AEA E + + ++G E LE+
Sbjct: 1956 EEAARARAEALQEALGKAHAALQGKEQHLLEQ 1987
Score = 35.8 bits (81), Expect = 0.069
Identities = 47/236 (19%), Positives = 89/236 (37%), Gaps = 17/236 (7%)
Query: 54 EELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKA 113
E L +QE + L E+I ++E + R L E +K S G +
Sbjct: 1490 EHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLK 1549
Query: 114 RPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQ--- 170
+ LA E ++ K + ++ + RE VA + D Q
Sbjct: 1550 KQLVTLECLALELEENHHKMECQ-QKLIKELEGQRETQRVALTHLTLDLEERSQELQAQS 1608
Query: 171 ----EMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYF 226
++ +H+T E +E + + +++ L +Q E Q L++ + +
Sbjct: 1609 SQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELM------- 1661
Query: 227 ELKAQFSQILEEHKAKVTE-LEQQVAQAKTRYSVALRNLEQISEQIHARRRGGLPP 281
L+ + Q+LE+ + + T+ LE+ + Q K R L + + R G P
Sbjct: 1662 -LQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGP 1716
Score = 31.6 bits (70), Expect = 1.3
Identities = 56/265 (21%), Positives = 110/265 (41%), Gaps = 43/265 (16%)
Query: 41 SSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQL----DEAR----------- 85
S S E +L + EEL +++LE L Q + + +V ++L D A+
Sbjct: 460 SLSKERELLQKAREEL----RQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELH 515
Query: 86 --TTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRLA----KEAQQETQKAALRYER 139
R LQE L + S S + R E+ L ++ Q E A R E+
Sbjct: 516 LAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQ 575
Query: 140 AVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTR 199
+++ +++ + + A +L + + A KV ++ L+ E E+Q V
Sbjct: 576 SIAELSSSENTLKTEVADLRAAAVKLSALNEAL---ALDKVG-LNQQLLQLEEENQSVCS 631
Query: 200 LCQQAEARVQALQKTL------RRAIGKSRPYFELK--------AQFSQILEEHKAKVTE 245
+ AE ALQ L R A+ + + E + A+ L + + + E
Sbjct: 632 RMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEE 691
Query: 246 LEQQVAQAKTRYSVALRNLEQISEQ 270
+++++++++ + A LEQ+ ++
Sbjct: 692 IQKKLSESRHQQEAATTQLEQLHQE 716
>gi|59806361 hypothetical protein LOC387104 [Homo sapiens]
Length = 947
Score = 45.1 bits (105), Expect = 1e-04
Identities = 59/265 (22%), Positives = 117/265 (44%), Gaps = 39/265 (14%)
Query: 20 PEVVEDEVPRSPVAEEPGGGGSSSSEAKLSPREEEELDPR--IQEELEHLNQASE----E 73
P E P+ GGG ++ S ++L + +QEE+E L + +E E
Sbjct: 310 PMAAAAEGPQQSAEGSASGGGMQAAAPPSSQPHPQQLQEQEEMQEEMEKLREENETLKNE 369
Query: 74 INQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQETQKA 133
I+++ ++DE R T+ +E A +L L E+A + R+ + ++ ++
Sbjct: 370 IDELRTEMDEMRDTF---FEEDACQLQEMRHEL----ERAN---KNCRILQYRLRKAERK 419
Query: 134 ALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGERE 193
LRY + + E++ EQ + K+ L+H ++ EE+R E E
Sbjct: 420 RLRYAQTGEIDG---ELLRSLEQDLKVAKD-----VSVRLHH---ELENVEEKRTTTEDE 468
Query: 194 HQRVTRLCQQAEARVQALQK--------TLRRAIGKSRPYFELKAQFSQILEEHKAKVTE 245
++++ + + E QALQ +L+R K P E KAQ + E+++ +
Sbjct: 469 NEKLRQQLIEVEIAKQALQNELEKMKELSLKRRGSKDLPKSEKKAQQTPTEEDNE----D 524
Query: 246 LEQQVAQAKTRYSVALRNLEQISEQ 270
L+ Q+ K ++ + + +I ++
Sbjct: 525 LKCQLQFVKEEAALMRKKMAKIDKE 549
>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
Length = 1233
Score = 44.7 bits (104), Expect = 1e-04
Identities = 51/247 (20%), Positives = 107/247 (43%), Gaps = 22/247 (8%)
Query: 41 SSSSEAKLSPREEEELDPRIQEELEHLN-------QASEEINQVELQLDEARTTYRRILQ 93
S + E + + ++++ ++E+ + L Q +EI + + +L++ R Y + +
Sbjct: 244 SKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKE 303
Query: 94 ESARKLNTQGSHLGSCIEKARPYYEARR-----LAKEAQQETQKAALRYERAVSMHNAAR 148
++ K+ + S ++ A+ +Y+ R+ L KE +KA +E + + ++
Sbjct: 304 NTSHKIKKLEAAKKS-LQNAQKHYKKRKGDMDELEKE-MLSVEKARQEFEERMEEESQSQ 361
Query: 149 EMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARV 208
E+ + +RL +E A E E+ R ++ Q L ++ +
Sbjct: 362 GRDLTLEENQVKKYHRLK---EEASKRAATLAQELEKFN-RDQKADQDRLDLEERKKVET 417
Query: 209 QALQKTLRRAIGKSRPYFELKAQF----SQILEEHKAKVTELEQQVAQAKTRYSVALRNL 264
+A K R I +++ E ++ Q LEE K EL ++V AK R + L
Sbjct: 418 EAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKEL 477
Query: 265 EQISEQI 271
Q+ EQ+
Sbjct: 478 NQVMEQL 484
Score = 40.0 bits (92), Expect = 0.004
Identities = 45/237 (18%), Positives = 106/237 (44%), Gaps = 14/237 (5%)
Query: 52 EEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIE 111
E E+L+ + + + + + + +++VE +L E + ++++E +++ + S +
Sbjct: 234 EIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQ-QQIEKEIKEKDSELN 292
Query: 112 KARPYY------EARRLAK--EAQQETQKAALRYE-RAVSMHNAAREMVFVAEQGVMADK 162
+ RP Y + ++ K A++ Q A Y+ R M +EM+ V E+ +
Sbjct: 293 QKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSV-EKARQEFE 351
Query: 163 NRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKS 222
R++ Q T + N+ ++ E +R L Q+ E + + R +
Sbjct: 352 ERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEE 411
Query: 223 RPYFELKAQFSQIL---EEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQIHARRR 276
R E +A+ Q L EE++ ++ +LE+ + +K + +++E++ +R
Sbjct: 412 RKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKR 468
Score = 29.6 bits (65), Expect = 4.9
Identities = 24/90 (26%), Positives = 47/90 (52%), Gaps = 13/90 (14%)
Query: 46 AKLSPREEEELDPRIQEELE----HLNQASEEINQVELQLDEARTTYRRI--------LQ 93
+K S E+++L+ + EE+E +++ ++E+NQV QL +AR + +
Sbjct: 445 SKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQQRKAEIM 504
Query: 94 ESARKLNTQGSHLGSCIEKARPYYEARRLA 123
ES ++L GS G I+ +P + ++A
Sbjct: 505 ESIKRL-YPGSVYGRLIDLCQPTQKKYQIA 533
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 44.3 bits (103), Expect = 2e-04
Identities = 56/244 (22%), Positives = 99/244 (40%), Gaps = 55/244 (22%)
Query: 38 GGGSSSSEAKLSPREEEELDPRI----QEELEHLNQASEE----INQVELQLDEARTTYR 89
G S + K RE+ E R +EEL L Q EE + ++EL L EA+
Sbjct: 317 GKTSLHKDLKQKRREQREQRERRRAAKEEELLRLQQLQEEKERKLQELEL-LQEAQRQAE 375
Query: 90 RILQESARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAARE 149
R+LQE + +Q L +E E R + +A+ E L+ E A +E
Sbjct: 376 RLLQEEEERRRSQHRELQQALEGQLREAEQARASMQAEME-----LKEEEAARQRQRIKE 430
Query: 150 MVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRV----TRLCQQAE 205
+ +EM ++ EA + ++ R+ + V TRL ++ E
Sbjct: 431 L-------------------EEMQQ----RLQEALQLEVKARRDEESVRIAQTRLLEEEE 467
Query: 206 ARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLE 265
+++ L +LK + + +E + + EL+Q++AQ A + LE
Sbjct: 468 EKLKQLM--------------QLKEEQERYIERAQQEKEELQQEMAQQSRSLQQAQQQLE 513
Query: 266 QISE 269
++ +
Sbjct: 514 EVRQ 517
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 44.3 bits (103), Expect = 2e-04
Identities = 49/232 (21%), Positives = 99/232 (42%), Gaps = 25/232 (10%)
Query: 59 RIQEEL-EHLNQASEEINQVELQLDEARTTY------RRILQ-------ESARKLNTQGS 104
R QE+L E L N ++ +++E R T R+I + E + L+TQ +
Sbjct: 1668 RSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNT 1727
Query: 105 HLGSCIEK-----ARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVM 159
L + +K ++ E + +EA+ +KA A M ++ EQ
Sbjct: 1728 SLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKK-----EQDTS 1782
Query: 160 ADKNRLDPTWQEMLNHATCKVNEAEEERLR-GEREHQRVTRLCQQAEARVQALQKTLRRA 218
A R+ ++ + +++EAE+ L+ G+++ Q++ ++ E V++ QK A
Sbjct: 1783 AHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEA 1842
Query: 219 IGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQ 270
+ R + + + EE + + L+ V + + + R E+ EQ
Sbjct: 1843 VKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQ 1894
Score = 37.4 bits (85), Expect = 0.024
Identities = 45/235 (19%), Positives = 101/235 (42%), Gaps = 27/235 (11%)
Query: 52 EEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQE---SARKLNTQGSHLGS 108
+EEE++ + + L +E ++++ +D+ T ++ +E + K+ +
Sbjct: 934 DEEEINAELTAKKRKLE---DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAG 990
Query: 109 CIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAR---EMVFVAEQGVMADKNRL 165
E + ++ +EA Q+T E V+ A+ E +G + + +L
Sbjct: 991 LDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKL 1050
Query: 166 DPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLR--RAIGKSR 223
+ + A+E + E E Q++ ++ E + LQ + +A+G
Sbjct: 1051 RMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALG--- 1107
Query: 224 PYFELKAQFSQILEEHKAKVTELEQQV-------AQAKTRYSVALRNLEQISEQI 271
Q + ++E +A++ ELE+++ A+A+ + S R LE+ISE++
Sbjct: 1108 ------IQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERL 1156
Score = 37.4 bits (85), Expect = 0.024
Identities = 58/289 (20%), Positives = 112/289 (38%), Gaps = 51/289 (17%)
Query: 2 AELRQVPGGRETPQGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKLSPREE-------- 53
AEL++ T + R + D + R+ EE +L EE
Sbjct: 1361 AELQRALSKANTEVAQWRTKYETDAIQRTEELEE----AKKKLAQRLQAAEEHVEAVNAK 1416
Query: 54 ----EELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSC 109
E+ R+Q E+E L E N LD+ + + +IL E +K + L +
Sbjct: 1417 CASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEAS 1476
Query: 110 IEKARPYYEARRLAKEAQQET--QKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDP 167
++AR K A +E+ Q L+ E N +E+ + EQ K
Sbjct: 1477 QKEARSLGTELFKIKNAYEESLDQLETLKREN----KNLQQEISDLTEQIAEGGK----- 1527
Query: 168 TWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFE 227
+++E E+ + + E+E + ++AEA ++ + + R
Sbjct: 1528 -----------RIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILR---------- 1566
Query: 228 LKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQIHARRR 276
++ + +Q+ E K+ E ++++ Q K + +R +E + + A R
Sbjct: 1567 IQLELNQVKSEVDRKIAEKDEEIDQLKRNH---IRIVESMQSTLDAEIR 1612
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 44.3 bits (103), Expect = 2e-04
Identities = 49/232 (21%), Positives = 99/232 (42%), Gaps = 25/232 (10%)
Query: 59 RIQEEL-EHLNQASEEINQVELQLDEARTTY------RRILQ-------ESARKLNTQGS 104
R QE+L E L N ++ +++E R T R+I + E + L+TQ +
Sbjct: 1668 RSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNT 1727
Query: 105 HLGSCIEK-----ARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVM 159
L + +K ++ E + +EA+ +KA A M ++ EQ
Sbjct: 1728 SLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKK-----EQDTS 1782
Query: 160 ADKNRLDPTWQEMLNHATCKVNEAEEERLR-GEREHQRVTRLCQQAEARVQALQKTLRRA 218
A R+ ++ + +++EAE+ L+ G+++ Q++ ++ E V++ QK A
Sbjct: 1783 AHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEA 1842
Query: 219 IGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQ 270
+ R + + + EE + + L+ V + + + R E+ EQ
Sbjct: 1843 VKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQ 1894
Score = 37.4 bits (85), Expect = 0.024
Identities = 45/235 (19%), Positives = 101/235 (42%), Gaps = 27/235 (11%)
Query: 52 EEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQE---SARKLNTQGSHLGS 108
+EEE++ + + L +E ++++ +D+ T ++ +E + K+ +
Sbjct: 934 DEEEINAELTAKKRKLE---DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAG 990
Query: 109 CIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAR---EMVFVAEQGVMADKNRL 165
E + ++ +EA Q+T E V+ A+ E +G + + +L
Sbjct: 991 LDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKL 1050
Query: 166 DPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLR--RAIGKSR 223
+ + A+E + E E Q++ ++ E + LQ + +A+G
Sbjct: 1051 RMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALG--- 1107
Query: 224 PYFELKAQFSQILEEHKAKVTELEQQV-------AQAKTRYSVALRNLEQISEQI 271
Q + ++E +A++ ELE+++ A+A+ + S R LE+ISE++
Sbjct: 1108 ------IQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERL 1156
Score = 37.4 bits (85), Expect = 0.024
Identities = 58/289 (20%), Positives = 112/289 (38%), Gaps = 51/289 (17%)
Query: 2 AELRQVPGGRETPQGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKLSPREE-------- 53
AEL++ T + R + D + R+ EE +L EE
Sbjct: 1361 AELQRALSKANTEVAQWRTKYETDAIQRTEELEE----AKKKLAQRLQAAEEHVEAVNAK 1416
Query: 54 ----EELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSC 109
E+ R+Q E+E L E N LD+ + + +IL E +K + L +
Sbjct: 1417 CASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEAS 1476
Query: 110 IEKARPYYEARRLAKEAQQET--QKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDP 167
++AR K A +E+ Q L+ E N +E+ + EQ K
Sbjct: 1477 QKEARSLGTELFKIKNAYEESLDQLETLKREN----KNLQQEISDLTEQIAEGGK----- 1527
Query: 168 TWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFE 227
+++E E+ + + E+E + ++AEA ++ + + R
Sbjct: 1528 -----------RIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILR---------- 1566
Query: 228 LKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQIHARRR 276
++ + +Q+ E K+ E ++++ Q K + +R +E + + A R
Sbjct: 1567 IQLELNQVKSEVDRKIAEKDEEIDQLKRNH---IRIVESMQSTLDAEIR 1612
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.128 0.355
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,212,912
Number of Sequences: 37866
Number of extensions: 834336
Number of successful extensions: 7602
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 141
Number of HSP's successfully gapped in prelim test: 506
Number of HSP's that attempted gapping in prelim test: 5925
Number of HSP's gapped (non-prelim): 1854
length of query: 393
length of database: 18,247,518
effective HSP length: 104
effective length of query: 289
effective length of database: 14,309,454
effective search space: 4135432206
effective search space used: 4135432206
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.