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Search of human proteins with 241666448
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|241666448 RIB43A domain with coiled-coils 2 [Homo sapiens]
(377 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|241666448 RIB43A domain with coiled-coils 2 [Homo sapiens] 756 0.0
gi|72534784 RIB43A domain with coiled-coils 1 isoform 1 [Homo sa... 231 8e-61
gi|21450659 RIB43A domain with coiled-coils 1 isoform 2 [Homo sa... 94 2e-19
gi|148746195 trichohyalin [Homo sapiens] 58 2e-08
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 51 1e-06
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 51 1e-06
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 51 1e-06
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 51 2e-06
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 50 3e-06
gi|221139761 zinc finger protein 853 [Homo sapiens] 50 3e-06
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 50 3e-06
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 50 4e-06
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 49 1e-05
gi|41281453 serine/threonine kinase 2 [Homo sapiens] 48 1e-05
gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens] 48 2e-05
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 47 4e-05
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 46 5e-05
gi|30794488 kinesin family member 27 [Homo sapiens] 46 5e-05
gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 45 1e-04
gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 45 1e-04
gi|13259508 dynactin 1 isoform 2 [Homo sapiens] 45 1e-04
gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 45 1e-04
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 45 1e-04
gi|4885583 Rho-associated, coiled-coil containing protein kinase... 44 2e-04
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 44 2e-04
gi|126362971 serine/threonine kinase 10 [Homo sapiens] 44 2e-04
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 44 2e-04
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 44 2e-04
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 44 2e-04
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 44 2e-04
>gi|241666448 RIB43A domain with coiled-coils 2 [Homo sapiens]
Length = 377
Score = 756 bits (1953), Expect = 0.0
Identities = 377/377 (100%), Positives = 377/377 (100%)
Query: 1 MAVALPRDLRQDANLAKRRHAELCRQKRVFNARNRIIGGDTEAWDVQVHDQKIKEATEKA 60
MAVALPRDLRQDANLAKRRHAELCRQKRVFNARNRIIGGDTEAWDVQVHDQKIKEATEKA
Sbjct: 1 MAVALPRDLRQDANLAKRRHAELCRQKRVFNARNRIIGGDTEAWDVQVHDQKIKEATEKA 60
Query: 61 RHETFAAEMRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKK 120
RHETFAAEMRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKK
Sbjct: 61 RHETFAAEMRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKK 120
Query: 121 DLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCA 180
DLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCA
Sbjct: 121 DLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCA 180
Query: 181 EALYTETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNL 240
EALYTETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNL
Sbjct: 181 EALYTETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNL 240
Query: 241 AEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQE 300
AEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQE
Sbjct: 241 AEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQE 300
Query: 301 EKRQRDLDWDRRRIQGARATLLFERQQWRRQRDLRRALDSSNLSLAKEQHLQKKYMNEVY 360
EKRQRDLDWDRRRIQGARATLLFERQQWRRQRDLRRALDSSNLSLAKEQHLQKKYMNEVY
Sbjct: 301 EKRQRDLDWDRRRIQGARATLLFERQQWRRQRDLRRALDSSNLSLAKEQHLQKKYMNEVY 360
Query: 361 TNQPTGDYFTQFNTGSR 377
TNQPTGDYFTQFNTGSR
Sbjct: 361 TNQPTGDYFTQFNTGSR 377
>gi|72534784 RIB43A domain with coiled-coils 1 isoform 1 [Homo
sapiens]
Length = 379
Score = 231 bits (589), Expect = 8e-61
Identities = 135/371 (36%), Positives = 208/371 (56%), Gaps = 1/371 (0%)
Query: 8 DLRQDANLAKRRHAELCRQKRVFNARNRIIGGDTEAWDVQVHDQKIKEATEKARHETFAA 67
D ++ A + RR+ E RQ R FN RNR++G D +A + QV D+K +EA E+++ +
Sbjct: 9 DTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGT 68
Query: 68 EMRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKKDLPARQS 127
Q D ++ +LE + + L + + +F++ Q+ + REF L DP + K LP S
Sbjct: 69 SQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLS 128
Query: 128 DNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTET 187
++ + +Q F GEDL+ R + Q+ Q R +QQ+E + A+ ++ +AL +
Sbjct: 129 YSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDALSNQL 188
Query: 188 RLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNLAEITNLL 247
RL D A HL +LE + R A+ ++ + NK+QA R++ E+++EQ+ NLAEI +
Sbjct: 189 RLAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRCERQREQKANLAEIQHQS 248
Query: 248 RGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQRDL 307
DLL+ENPQ A P+RV+P WKGMT EQ IR Q+ Q +K ++ ++ D
Sbjct: 249 TSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHRQAEKTLDT 308
Query: 308 DWDRRRIQGARATLLFERQQWRRQRDLRRALDSSNLSLAKEQHLQKKYMNEV-YTNQPTG 366
+W + + A+A L E Q+ +R L S N LA EQ Q+ Y+N V YTNQPT
Sbjct: 309 EWKSQTMSSAQAVLELEEQERELCAVFQRGLGSFNQQLANEQKAQQDYLNSVIYTNQPTA 368
Query: 367 DYFTQFNTGSR 377
Y QFNT SR
Sbjct: 369 QYHQQFNTSSR 379
>gi|21450659 RIB43A domain with coiled-coils 1 isoform 2 [Homo
sapiens]
Length = 192
Score = 94.0 bits (232), Expect = 2e-19
Identities = 54/170 (31%), Positives = 94/170 (55%)
Query: 8 DLRQDANLAKRRHAELCRQKRVFNARNRIIGGDTEAWDVQVHDQKIKEATEKARHETFAA 67
D ++ A + RR+ E RQ R FN RNR++G D +A + QV D+K +EA E+++ +
Sbjct: 9 DTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGT 68
Query: 68 EMRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKKDLPARQS 127
Q D ++ +LE + + L + + +F++ Q+ + REF L DP + K LP S
Sbjct: 69 SQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLS 128
Query: 128 DNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQ 177
++ + +Q F GEDL+ R + Q+ Q R +QQ+E + A+ ++
Sbjct: 129 YSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDE 178
Score = 32.0 bits (71), Expect = 0.94
Identities = 36/171 (21%), Positives = 77/171 (45%), Gaps = 26/171 (15%)
Query: 151 RKKFQEEQNREWSLQ-------------QQREWKNARAEQKCAEALYTETRLQFDETAKH 197
R + +E QNR ++++ Q + K A ++ EA Y +++Q+D +
Sbjct: 20 RNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDVVVQM 79
Query: 198 LQKLESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNLAEITNLLRGDLLSENPQ 257
L+K E+ + + V++F + +KQ+ K +E +L + + +G L
Sbjct: 80 LEKEEADRTRQLAKKVQEFRE---------QKQQLKNGREFSLWDPGQVWKG--LPTYLS 128
Query: 258 QAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQRDLD 308
+ + GP + + G ++ ++R+ Q Q R Q+E++Q +D
Sbjct: 129 YSNTYPGPASL--QYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVD 177
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 57.8 bits (138), Expect = 2e-08
Identities = 72/312 (23%), Positives = 146/312 (46%), Gaps = 31/312 (9%)
Query: 50 DQKIKEATEKARHETFAAEMRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETRRE 109
+Q+ + ++ RH ++ + ++ +RK ++ K L R + ++ ++ ET R+
Sbjct: 1280 EQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLR--EEREEKRRRQETDRK 1337
Query: 110 FDLSDPLALKKD-LPARQSDNDVRNTISGMQKFMGEDLNFHER-KKFQEEQNREWSLQQQ 167
F + L +++ P R+ + D +KF E+L E+ +KF EE+ R +++
Sbjct: 1338 FREEEQLLQEREEQPLRRQERD--------RKFREEELRHQEQGRKFLEEEQRLRRQERE 1389
Query: 168 REWKNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESVER 227
R++ + +C E E +L+ D K ++ + +R+ +D + + V R
Sbjct: 1390 RKFLKEEQQLRCQER---EQQLRQDRDRKFREEEQQLSRQE-----RDRKFREEEQQVRR 1441
Query: 228 KKQEKK--QEQEDNLAEITNLLRGD--LLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQ 283
+++E+K +E++ E R + LL E +Q HR DR K + +EQ +
Sbjct: 1442 QERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQL-----HRQERDR-KFLEEEQQLR 1495
Query: 284 IRLVQKQQIQEKLRLQEEKRQRDLDWDRRRIQGARATLLFERQQWRRQ-RDLRRALDSSN 342
+ ++ +++LR QE +R+ + + Q + L E QQ RRQ R +R D
Sbjct: 1496 RQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDR 1555
Query: 343 LSLAKEQHLQKK 354
+EQ Q++
Sbjct: 1556 KFREEEQLRQER 1567
Score = 54.7 bits (130), Expect = 1e-07
Identities = 74/347 (21%), Positives = 147/347 (42%), Gaps = 51/347 (14%)
Query: 11 QDANLAKRRHAELCRQKRVFNARNRIIG---GDTEAWDVQVHDQKIKEATEKARHETFAA 67
+++ L RR E +R F R+R + G Q ++++ E E++ +
Sbjct: 106 KESLLQDRRQEE---DQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLE 162
Query: 68 EMRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKKDLPARQS 127
+ + + + R++ + RA + QS + ET EF + L ++ L R+
Sbjct: 163 QRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETE-EFPDEEQLRRRELLELRRK 221
Query: 128 DNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTET 187
+ + + + + FQEE+ +EW ++RE + E+K E
Sbjct: 222 GREEKQ----------QQRRERQDRVFQEEEEKEW---RKRETVLRKEEEKLQEEEPQRQ 268
Query: 188 RLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNLAEITNLL 247
R + E + L+KLE + + R++QE++Q+Q+ L L
Sbjct: 269 R-ELQEEEEQLRKLER-------------------QELRRERQEEEQQQQ-RLRREQQLR 307
Query: 248 RGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQRDL 307
R QQ R +R + + + +Q+R Q+++ +++LR ++E+ +R+
Sbjct: 308 RKQEEERREQQEE-----RREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQ 362
Query: 308 DWDRRRIQGARATLLFERQQWRRQRDLRRALDSSNLSLAKEQHLQKK 354
R + + R L QQ RR++ LRR L +EQ L+++
Sbjct: 363 QLRREQEEERREQQLRREQQLRREQQLRR-----EQQLRREQQLRRE 404
Score = 53.9 bits (128), Expect = 2e-07
Identities = 75/349 (21%), Positives = 146/349 (41%), Gaps = 25/349 (7%)
Query: 25 RQKRVFNARNRIIGGDTEAWDVQVHDQKIKEATEKARHETFAAEMRQNDKIMCILENRKK 84
R++++ R+R + + Q D+K +E ++ R + + + ++ + +RK
Sbjct: 1404 REQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKF 1463
Query: 85 RDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKKDLPARQSDNDVRNTISGMQKFMGE 144
R+ + L + +Q + E R+F L + L++ R+ + +KF+ E
Sbjct: 1464 REEEQLLQERE--EQQLHRQERDRKF-LEEEQQLRRQERDRKFREQELRSQEPERKFLEE 1520
Query: 145 DLNFH----ERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTETRLQFDETAKHLQK 200
+ H +RK QEEQ Q +R+ + + Q E +L+ + + L +
Sbjct: 1521 EQQLHRQQRQRKFLQEEQ------QLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSR 1574
Query: 201 LESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNL-AEITNLLRGD---LLSENP 256
E RK K + Q + +E ++Q ++QE + L E R D L
Sbjct: 1575 QE-RDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREE 1633
Query: 257 QQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQRDLDWDRRRIQG 316
QQ + + + + QE+ +Q+R + ++ +E+ +L +E ++ L R Q
Sbjct: 1634 QQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQL-----RRQE 1688
Query: 317 ARATLLFERQQWRRQRDLRRALDSSNLSLAKEQHLQKKYMNEVYTNQPT 365
E QQ RRQ R+ L + Q L++K+ E Q T
Sbjct: 1689 RDRKFREEEQQLRRQERERKFLQEE--QQLRRQELERKFREEEQLRQET 1735
Score = 53.5 bits (127), Expect = 3e-07
Identities = 74/375 (19%), Positives = 154/375 (41%), Gaps = 33/375 (8%)
Query: 17 KRRHAELCRQKRVFNARNR----------IIGGDTEAW--DVQVHDQKIKEATEKARHET 64
+RR EL RQ++ + R G +TE + + Q+ +++ E K R E
Sbjct: 167 QRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEK 226
Query: 65 FAAEMRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKKDLPA 124
+ D++ E ++ R R+ + R ++ Q+ E +R+ +L + + L
Sbjct: 227 QQQRRERQDRVFQEEEEKEWRKRETVLRKE---EEKLQEEEPQRQRELQEEEEQLRKLER 283
Query: 125 RQSDNDVRNTISGMQKFMGED-LNFHERKKFQEEQNREWSLQQQREWKNARAEQKCA--- 180
++ + + Q+ E L + ++ +E+Q Q++RE + R EQ+
Sbjct: 284 QELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQ 343
Query: 181 -EALYTETRLQFDETAKHLQ---KLESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQ 236
E + R + +E + Q + E R+ + + Q + ++ ++E++ +
Sbjct: 344 EERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRR 403
Query: 237 EDNLAEITNLLRGDLLSENPQ----QAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQI 292
E L L R L Q Q R + + +EQ E+ +++++
Sbjct: 404 EQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEE 463
Query: 293 QEKLRLQEEKRQRDLDWDRRRIQGARATLLFER----QQWRRQRDLRRALDSSNLSLAKE 348
E R ++E+R++ L D+ + R L E QQ RR++ LRR + K
Sbjct: 464 TE--RHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKR 521
Query: 349 QHLQKKYMNEVYTNQ 363
Q +++ + + Q
Sbjct: 522 QEEEERLQQRLRSEQ 536
Score = 53.5 bits (127), Expect = 3e-07
Identities = 78/365 (21%), Positives = 148/365 (40%), Gaps = 31/365 (8%)
Query: 7 RDLRQDANLAKRRHAE-LCRQKRVFNARN---RIIGGDTEAWDVQVHDQKIKEATEKARH 62
+ LRQD + R + L RQ+R R ++ + E ++ Q +E K R
Sbjct: 1406 QQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFRE 1465
Query: 63 ETFAAEMRQNDKIMCILENRKKRDRK------NLCRAINDF---QQSFQKPETRREFDLS 113
E + R+ ++ +R++RDRK L R D +Q + E R+F L
Sbjct: 1466 EEQLLQEREEQQL-----HRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKF-LE 1519
Query: 114 DPLALKKDLPAR---QSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREW 170
+ L + R Q + +R G Q+ D F E ++ ++E+ + +Q+R+
Sbjct: 1520 EEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDR 1579
Query: 171 KNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESVERKKQ 230
K EQK E +F E + L++ E + K Q ++ E ++
Sbjct: 1580 KFRLEEQKVRRQ---EQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQL 1636
Query: 231 EKKQEQEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQ 290
+++ L E L R + + F + + + E+ R +++
Sbjct: 1637 HRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREE 1696
Query: 291 QIQ------EKLRLQEEKRQRDLDWDRRRIQGARATLLFERQQWRRQRDLRRALDSSNLS 344
+ Q E+ LQEE++ R + +R+ + + E++Q RRQ R+ L+ L
Sbjct: 1697 EQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLR 1756
Query: 345 LAKEQ 349
+E+
Sbjct: 1757 PEREE 1761
Score = 50.8 bits (120), Expect = 2e-06
Identities = 76/358 (21%), Positives = 146/358 (40%), Gaps = 48/358 (13%)
Query: 47 QVHDQKIKEATEKARHETFAAEMRQNDKIM-----CILENRKKR---DRKNLCRAINDFQ 98
Q +Q ++E EK R + + + R+ D++ + E R+KR +R+ R + Q
Sbjct: 998 QEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQ 1057
Query: 99 QSFQK-----PETRREFDLSDPLALKKDLPARQSDNDVRNTISGMQKFMGEDLNFHERKK 153
Q ++ ETRR +L +++L + ++ + E+ R++
Sbjct: 1058 QEEEQLLGEERETRRRQELERQYRKEEELQQEE------------EQLLREEPEKRRRQE 1105
Query: 154 FQEEQNREWSLQQQ-----REWKNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKA 208
+ + E LQQ+ RE + R Q+ E +Q +E ++ E R+
Sbjct: 1106 RERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQE 1165
Query: 209 VCASVKDFNK-SQAIESVERKKQEKK-QEQEDNLAEITNLLR-------------GDLLS 253
+ ++ + Q E + R++QEK+ QE+E E L R DL
Sbjct: 1166 LERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKW 1225
Query: 254 ENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQRDLDWDRRR 313
+ + ++ ++V + QLE +L +Q Q+ L E+++RD + +RRR
Sbjct: 1226 QWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRR 1285
Query: 314 IQGARATLLFERQQWRRQRDLRRALDSSNLSLAKEQHLQKKYMNEVYTNQPTGDYFTQ 371
Q E Q R ++ + D + +E+ L ++ E Q T F +
Sbjct: 1286 WQQRDRHFPEEEQLEREEQKEAKRRDRKS---QEEKQLLREEREEKRRRQETDRKFRE 1340
Score = 49.3 bits (116), Expect = 6e-06
Identities = 65/320 (20%), Positives = 134/320 (41%), Gaps = 18/320 (5%)
Query: 51 QKIKEATEKARHETFAAEMRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETRREF 110
Q ++E E+ + E RQ + E + +++ + L R + ++ ++ E R++
Sbjct: 904 QLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLR---EEREKRRRQERERQY 960
Query: 111 DLSDPLALKKDLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNR----EWSLQQ 166
L K++ + R + E+L E + +EE+ + EW Q
Sbjct: 961 RKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQY 1020
Query: 167 QREWKNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESVE 226
+++ + + E++ + RLQ E ++ + + ++ + Q +E
Sbjct: 1021 RKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQY 1080
Query: 227 RKKQEKKQEQEDNLAEITNLLRGDLLSE--NPQQAASSFGPHRVVPDRWKGMTQEQLEQI 284
RK++E +QE+E L E R ++ + +R K QE Q
Sbjct: 1081 RKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQY 1140
Query: 285 RLVQKQQIQEKLRLQEE---KRQRDLDWDRR---RIQGARATLLFERQQWRRQRDLRRAL 338
R ++ Q +E+ L+EE +R+++L+ R +Q LL E Q+ RRQ R+
Sbjct: 1141 REEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYR 1200
Query: 339 DSSNLSLAKEQHLQKKYMNE 358
+ L + Q +++Y +E
Sbjct: 1201 EEEEL---QRQKRKQRYRDE 1217
Score = 48.5 bits (114), Expect = 1e-05
Identities = 54/313 (17%), Positives = 132/313 (42%), Gaps = 16/313 (5%)
Query: 51 QKIKEATEKARHETFAAEMRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETRREF 110
Q+ +E K + E ++ + + +++ R+ R + ++ Q+ E R +
Sbjct: 272 QEEEEQLRKLERQELRRERQEEE------QQQQRLRREQQLRRKQEEERREQQEERREQQ 325
Query: 111 DLSDPLALKKDLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSL---QQQ 167
+ + +++ R+ + R +++ E+ + ++ QEE+ RE L QQ
Sbjct: 326 ERREQQEERREQQLRREQEERRE--QQLRREQEEERREQQLRREQEEERREQQLRREQQL 383
Query: 168 REWKNARAEQKCA--EALYTETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESV 225
R + R EQ+ + L E +L+ ++ + Q+L R+ ++ + +
Sbjct: 384 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR---REQQLRREQEEERHEQKHEQ 440
Query: 226 ERKKQEKKQEQEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIR 285
ER++Q K+EQE+ + + + ++ +RW + +E+ + +
Sbjct: 441 ERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQ 500
Query: 286 LVQKQQIQEKLRLQEEKRQRDLDWDRRRIQGARATLLFERQQWRRQRDLRRALDSSNLSL 345
++QQ++ + + E+R + + + R Q R+ R+Q R+ L + + L
Sbjct: 501 ERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQ 560
Query: 346 AKEQHLQKKYMNE 358
+ + K+ E
Sbjct: 561 ERREQRLKREQEE 573
Score = 47.0 bits (110), Expect = 3e-05
Identities = 61/324 (18%), Positives = 132/324 (40%), Gaps = 29/324 (8%)
Query: 50 DQKIKEATEKARHET-FAAEMRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETRR 108
+Q++K E+ R E E + + + E +++ R+ + I +Q + R
Sbjct: 656 EQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADAR 715
Query: 109 EFDLSDPLALKKDLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQR 168
+ + ++ RQ + R ++ E+ R++ +EEQ R+++ Q Q
Sbjct: 716 QSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERA--HRQQQEEEQRRDFTWQWQA 773
Query: 169 EWKNARAEQKCAEAL----YTETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIES 224
E K+ R Q+ + E +L+ +E + Q+ + + + + ++
Sbjct: 774 EEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQF 833
Query: 225 VERKKQEKKQEQEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQI 284
+E ++Q +++E+ L E + L+ D Q+ +W+ +E+ ++
Sbjct: 834 LEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRD--------QKWRWQLEEERKRR 885
Query: 285 R--LVQKQQIQEKLR------------LQEEKRQRDLDWDRRRIQGARATLLFERQQWRR 330
R L K +QE+LR LQ E+R++ ++ R L E +Q R
Sbjct: 886 RHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLR 945
Query: 331 QRDLRRALDSSNLSLAKEQHLQKK 354
+ +R K++ LQ+K
Sbjct: 946 EEREKRRRQERERQYRKDKKLQQK 969
Score = 46.6 bits (109), Expect = 4e-05
Identities = 73/342 (21%), Positives = 142/342 (41%), Gaps = 35/342 (10%)
Query: 50 DQKIKEATEKARHETFAAEMRQNDKIMCILENRK---KRDRKNLCRAINDFQQSFQKP-- 104
+Q+++ E+ RHE + R+ ++ E R+ KR+ + +Q ++
Sbjct: 422 EQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE 481
Query: 105 ETRREFDLSDPLALKKDLPARQSDNDVRNTISGMQ---KFMGEDLNFHERKKFQEEQNRE 161
E RRE L +++ R+ R + K E+ +R + +++ RE
Sbjct: 482 EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRRE 541
Query: 162 WSLQQQREWKNARAEQKCAEALYTETRL--QFDETAKHLQKLESTTRKAVCASVKDFNKS 219
+++RE R E+K E E RL + +E L K E R+ ++
Sbjct: 542 Q--EERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLE 599
Query: 220 QAI--ESVERKKQEKKQEQEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMT 277
Q + E VER +QE+++EQ E R LL Q+ R +R +
Sbjct: 600 QRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRL 659
Query: 278 QEQLEQIRLVQK-QQIQEKLRLQEEKRQRDLDWDRRRIQG--------------ARATLL 322
+ + E+ RL Q+ ++ E+ R ++E + + + R RI+ AR + +
Sbjct: 660 KREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKV 719
Query: 323 FER------QQWRRQRDLRRALDSSNLSLAKEQHLQKKYMNE 358
+ R Q+ R++++ +R S L +E+ ++ E
Sbjct: 720 YSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEE 761
Score = 42.0 bits (97), Expect = 0.001
Identities = 60/297 (20%), Positives = 126/297 (42%), Gaps = 25/297 (8%)
Query: 47 QVHDQKIKEATEKARHETFAAEMRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPET 106
Q +K + ++ R + + RQ+ +RK R+ + L + + Q S Q E
Sbjct: 1527 QQRQRKFLQEEQQLRRQERGQQRRQD-------RDRKFREEEQLRQEREEQQLSRQ--ER 1577
Query: 107 RREFDLSDPLALKKDLPAR--QSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSL 164
R+F L + +++ + + + +R Q D F E ++ +E+ +
Sbjct: 1578 DRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLH 1637
Query: 165 QQQREWKNARAE-----QKCAEALYTETRLQFDETAKHLQKLESTTRKAVCASVKDFNKS 219
+Q+R+ K E Q+ + L + +F E + LQ+ E + K +
Sbjct: 1638 RQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEE 1697
Query: 220 QAIESVERKKQEKKQEQEDNLAEITNLLRGD--LLSENPQQAASSFGPHRVVPDRWKGMT 277
Q + ER+++ ++EQ+ E+ R + L E Q+ +R + +
Sbjct: 1698 QQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKI------LE 1751
Query: 278 QEQLEQIRLVQKQQIQEKLRLQEEKRQRDLDWDRRRIQGARATLLF-ERQQWRRQRD 333
+EQL R Q+ + QE+ R E+ Q + + ++++ + F E +Q R++R+
Sbjct: 1752 EEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQERE 1808
Score = 41.2 bits (95), Expect = 0.002
Identities = 68/353 (19%), Positives = 147/353 (41%), Gaps = 43/353 (12%)
Query: 7 RDLRQDANLAKRRHAE-LCRQKRVFNARNRIIGGDTEAWDVQVHDQKIKEATEKARHETF 65
R R++ L + R + L RQ+R +R + + Q ++K E ++ R +
Sbjct: 1555 RKFREEEQLRQEREEQQLSRQER-----DRKFRLEEQKVRRQEQERKFMEDEQQLRRQEG 1609
Query: 66 AAEMRQ--NDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKKDLP 123
++RQ + K + ++R+ + L R D + ++P+ RR+ + L +D
Sbjct: 1610 QQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQ-EREQQLRHDRDRK 1668
Query: 124 ARQSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWS-LQQQREWKNARAEQKCAEA 182
R+ + ++ + D F E ++ Q RE LQ++++ + E+K E
Sbjct: 1669 FREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFRE- 1727
Query: 183 LYTETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNLAE 242
E +L+ + + L++ E + ++ + Q + ER ++ +++EQ E
Sbjct: 1728 ---EEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQERE 1784
Query: 243 ITNLL--RGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQ--------- 291
L D +Q ++ P + G + + EQ++L +++Q
Sbjct: 1785 EQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQ 1844
Query: 292 --------IQEKLRLQEEKRQRDLDWDRRRIQGARATLLFERQQWRRQRDLRR 336
QEK R +E++ ++ + RR+ ER++ R+ +RR
Sbjct: 1845 YRAEEQFATQEKSRREEQELWQEEEQKRRQ----------ERERKLREEHIRR 1887
Score = 36.6 bits (83), Expect = 0.038
Identities = 34/145 (23%), Positives = 63/145 (43%), Gaps = 7/145 (4%)
Query: 220 QAIESVERKKQEKKQEQEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQE 279
Q E +++++K+QEQE LAE G+ SE Q+ R + W+ +
Sbjct: 128 QLEEEPGQRRRQKRQEQERELAE------GEEQSEK-QERLEQRDRQRRDEELWRQRQEW 180
Query: 280 QLEQIRLVQKQQIQEKLRLQEEKRQRDLDWDRRRIQGARATLLFERQQWRRQRDLRRALD 339
Q + R +++Q+Q + E+ + RR + R E+QQ RR+R R +
Sbjct: 181 QEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQE 240
Query: 340 SSNLSLAKEQHLQKKYMNEVYTNQP 364
K + + +K ++ +P
Sbjct: 241 EEEKEWRKRETVLRKEEEKLQEEEP 265
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 51.2 bits (121), Expect = 1e-06
Identities = 65/307 (21%), Positives = 137/307 (44%), Gaps = 41/307 (13%)
Query: 48 VHDQKIKEATEKARHETFAAEMRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETR 107
+ D+++KE + + + E +++ + + + ++K +R L QQ Q R
Sbjct: 211 ITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLP----QQQLQVEADR 266
Query: 108 REFDLSDPLALKKDLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNR----EWS 163
+L ++ L A+ +N++ N ++ Q E+ + + +K QE++ + E
Sbjct: 267 LGKELQ---SVSAKLQAQVEENELWNLLNQQQ----EEKMWRQEEKIQEQEEKMCEQELK 319
Query: 164 LQQQREWKNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIE 223
+++Q E K R E+K E + R Q D+ + +K+ K K + + + I
Sbjct: 320 IREQEE-KMWRQEEKMHEQ-EEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIR 377
Query: 224 SVERKKQEKKQE---QEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKG----- 275
+ K QE+++E QE+ + E + + + + + W+
Sbjct: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437
Query: 276 ----MTQEQLEQIRLVQK--QQIQEKLRLQEEKRQRDLDWDRRRIQGARATLLFERQQWR 329
M Q+Q E++R V++ Q+ +EK++ QEEK QR +IQ E + WR
Sbjct: 438 ELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQR----QEEKIQEQ------EEKTWR 487
Query: 330 RQRDLRR 336
+++ L++
Sbjct: 488 QEKLLKQ 494
Score = 38.5 bits (88), Expect = 0.010
Identities = 51/226 (22%), Positives = 97/226 (42%), Gaps = 41/226 (18%)
Query: 142 MGEDLNFHERK-KFQEEQNREWSL-QQQREWKNARAEQKCAEALYTETRLQFDETAKHLQ 199
+G++L K + Q E+N W+L QQ+E K R E+K E Q ++ +
Sbjct: 267 LGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQE--------QEEKMCEQEL 318
Query: 200 KLESTTRKAVCASVKDFNKSQAIESVERK---KQEKKQEQEDNLAEITNLLRGDLLSENP 256
K+ K K + + I E K ++EK +EQE+ + E +
Sbjct: 319 KIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMW-------- 370
Query: 257 QQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQ--QIQEKLRLQEEKRQRDLDWDRRRI 314
R + +EQ E+I+ +++ + +EK+R QEEKRQ + W + +
Sbjct: 371 ---------------RQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKM-WRQEKK 414
Query: 315 QGARATLLFERQQ--WRRQRDLRRALDSSNLSLAKEQHLQKKYMNE 358
+ + E+++ WR++ +R + K + +++K E
Sbjct: 415 MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEE 460
Score = 37.7 bits (86), Expect = 0.017
Identities = 55/300 (18%), Positives = 131/300 (43%), Gaps = 34/300 (11%)
Query: 40 DTEAWDV--QVHDQKIKEATEKARHETFAAEMRQNDKIMCILENRKKRDRKNLCRAINDF 97
+ E W++ Q ++K+ EK +++ ++ MC E + + + + R
Sbjct: 284 ENELWNLLNQQQEEKMWRQEEK---------IQEQEEKMCEQELKIREQEEKMWRQEEKM 334
Query: 98 QQSFQKPETRREFDLSDPLALKKDLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQEE 157
+ Q+ + R + D +++ R+ + +R M + E+ + +K QE+
Sbjct: 335 HE--QEEKIREQEDKM----WRQEEKIREQEEKIREQEEKMWR--QEEKIREQDEKIQEQ 386
Query: 158 QNREWSLQQQ-REWKNARAEQKCA-EALYTETRLQFDETAKHLQKLESTTRKAVCASVKD 215
+ W +++ RE + R E+ E E + E + + + E R+
Sbjct: 387 EEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQ 446
Query: 216 FNKSQAIESVERKKQEKKQEQEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKG 275
K + +E ++++EK QEQE+ + ++ +Q ++ +++ K
Sbjct: 447 EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQ--------EQEEKTWRQEKLLKQEEKI 498
Query: 276 MTQEQLEQIRLVQKQQIQEKLRLQEEKRQRDLDWDRRRIQGARATLLFERQQWRRQRDLR 335
QE+ + + + +EK++ QEEK QR ++ R Q R L+++++ +++++R
Sbjct: 499 WEQEEKMWRQEEKMWEQEEKMQEQEEKMQR--QEEKMREQEVR---LWQQEEKMQEQEVR 553
Score = 33.1 bits (74), Expect = 0.42
Identities = 54/255 (21%), Positives = 107/255 (41%), Gaps = 17/255 (6%)
Query: 114 DPLALKKDLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNA 173
+ L ++D P+ + RNTI+ ++ ++ E+ + E + E L K+
Sbjct: 193 EKLTKERDAPSLEL---YRNTITD-EELKEKNAELQEKLRLVESEKSEIQLNV----KDL 244
Query: 174 RAEQKCAEALYTETRLQF--DETAKHLQKLESTTRKAVCASVKDFNKSQAIESVERKKQE 231
+ + + A+ L + +LQ D K LQ + + + V + +Q E +++E
Sbjct: 245 KRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEE 304
Query: 232 KKQEQEDNLAEITNLLRGD-----LLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRL 286
K QEQE+ + E +R E + R + +EQ E+IR
Sbjct: 305 KIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIRE 364
Query: 287 VQKQ--QIQEKLRLQEEKRQRDLDWDRRRIQGARATLLFERQQWRRQRDLRRALDSSNLS 344
+++ + +EK+R Q+EK Q + R+ + R +++ RQ R D
Sbjct: 365 QEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIRE 424
Query: 345 LAKEQHLQKKYMNEV 359
+E Q++ + E+
Sbjct: 425 QEEEMWRQEEKIREL 439
Score = 32.3 bits (72), Expect = 0.72
Identities = 43/240 (17%), Positives = 100/240 (41%), Gaps = 34/240 (14%)
Query: 9 LRQDANLAKRRHAELCRQKRVFNARN-RIIGGDTEAWDVQVHDQKIKEATEKARHETFAA 67
+R+ + + ++ RQ+ ++ +I + E W ++KI+E EK + + +
Sbjct: 355 IREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWR---QEEKIREQEEKRQEKMWRQ 411
Query: 68 EMRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKKDLPARQS 127
E + ++ I E ++ R+ I + ++ Q E + R+
Sbjct: 412 EKKMREQDEKIREQEEEMWRQE--EKIRELEEMMQDQEEK----------------LREV 453
Query: 128 DNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTET 187
+ ++ MQ+ E+ + +K QE++ + W ++ + + EQ+ E ++ +
Sbjct: 454 EEKMQEEEEKMQE--QEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQE--EKMWRQE 509
Query: 188 RLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNLAEITNLL 247
+++ K ++ E R+ K + E +++EK QEQE L E+ L
Sbjct: 510 EKMWEQEEKMQEQEEKMQRQE--------EKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 51.2 bits (121), Expect = 1e-06
Identities = 65/307 (21%), Positives = 137/307 (44%), Gaps = 41/307 (13%)
Query: 48 VHDQKIKEATEKARHETFAAEMRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETR 107
+ D+++KE + + + E +++ + + + ++K +R L QQ Q R
Sbjct: 211 ITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLP----QQQLQVEADR 266
Query: 108 REFDLSDPLALKKDLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNR----EWS 163
+L ++ L A+ +N++ N ++ Q E+ + + +K QE++ + E
Sbjct: 267 LGKELQ---SVSAKLQAQVEENELWNLLNQQQ----EEKMWRQEEKIQEQEEKMCEQELK 319
Query: 164 LQQQREWKNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIE 223
+++Q E K R E+K E + R Q D+ + +K+ K K + + + I
Sbjct: 320 IREQEE-KMWRQEEKMHEQ-EEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIR 377
Query: 224 SVERKKQEKKQE---QEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKG----- 275
+ K QE+++E QE+ + E + + + + + W+
Sbjct: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437
Query: 276 ----MTQEQLEQIRLVQK--QQIQEKLRLQEEKRQRDLDWDRRRIQGARATLLFERQQWR 329
M Q+Q E++R V++ Q+ +EK++ QEEK QR +IQ E + WR
Sbjct: 438 ELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQR----QEEKIQEQ------EEKTWR 487
Query: 330 RQRDLRR 336
+++ L++
Sbjct: 488 QEKLLKQ 494
Score = 38.5 bits (88), Expect = 0.010
Identities = 51/226 (22%), Positives = 97/226 (42%), Gaps = 41/226 (18%)
Query: 142 MGEDLNFHERK-KFQEEQNREWSL-QQQREWKNARAEQKCAEALYTETRLQFDETAKHLQ 199
+G++L K + Q E+N W+L QQ+E K R E+K E Q ++ +
Sbjct: 267 LGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQE--------QEEKMCEQEL 318
Query: 200 KLESTTRKAVCASVKDFNKSQAIESVERK---KQEKKQEQEDNLAEITNLLRGDLLSENP 256
K+ K K + + I E K ++EK +EQE+ + E +
Sbjct: 319 KIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMW-------- 370
Query: 257 QQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQ--QIQEKLRLQEEKRQRDLDWDRRRI 314
R + +EQ E+I+ +++ + +EK+R QEEKRQ + W + +
Sbjct: 371 ---------------RQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKM-WRQEKK 414
Query: 315 QGARATLLFERQQ--WRRQRDLRRALDSSNLSLAKEQHLQKKYMNE 358
+ + E+++ WR++ +R + K + +++K E
Sbjct: 415 MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEE 460
Score = 37.7 bits (86), Expect = 0.017
Identities = 55/300 (18%), Positives = 131/300 (43%), Gaps = 34/300 (11%)
Query: 40 DTEAWDV--QVHDQKIKEATEKARHETFAAEMRQNDKIMCILENRKKRDRKNLCRAINDF 97
+ E W++ Q ++K+ EK +++ ++ MC E + + + + R
Sbjct: 284 ENELWNLLNQQQEEKMWRQEEK---------IQEQEEKMCEQELKIREQEEKMWRQEEKM 334
Query: 98 QQSFQKPETRREFDLSDPLALKKDLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQEE 157
+ Q+ + R + D +++ R+ + +R M + E+ + +K QE+
Sbjct: 335 HE--QEEKIREQEDKM----WRQEEKIREQEEKIREQEEKMWR--QEEKIREQDEKIQEQ 386
Query: 158 QNREWSLQQQ-REWKNARAEQKCA-EALYTETRLQFDETAKHLQKLESTTRKAVCASVKD 215
+ W +++ RE + R E+ E E + E + + + E R+
Sbjct: 387 EEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQ 446
Query: 216 FNKSQAIESVERKKQEKKQEQEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKG 275
K + +E ++++EK QEQE+ + ++ +Q ++ +++ K
Sbjct: 447 EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQ--------EQEEKTWRQEKLLKQEEKI 498
Query: 276 MTQEQLEQIRLVQKQQIQEKLRLQEEKRQRDLDWDRRRIQGARATLLFERQQWRRQRDLR 335
QE+ + + + +EK++ QEEK QR ++ R Q R L+++++ +++++R
Sbjct: 499 WEQEEKMWRQEEKMWEQEEKMQEQEEKMQR--QEEKMREQEVR---LWQQEEKMQEQEVR 553
Score = 32.3 bits (72), Expect = 0.72
Identities = 51/237 (21%), Positives = 99/237 (41%), Gaps = 14/237 (5%)
Query: 132 RNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTETRLQF 191
RNTI+ ++ ++ E+ + E + E L K+ + + + A+ L + +LQ
Sbjct: 208 RNTITD-EELKEKNAELQEKLRLVESEKSEIQLNV----KDLKRKLERAQLLLPQQQLQV 262
Query: 192 --DETAKHLQKLESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNLAEITNLLRG 249
D K LQ + + + V + +Q E +++EK QEQE+ + E +R
Sbjct: 263 EADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIRE 322
Query: 250 D-----LLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQ--QIQEKLRLQEEK 302
E + R + +EQ E+IR +++ + +EK+R Q+EK
Sbjct: 323 QEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEK 382
Query: 303 RQRDLDWDRRRIQGARATLLFERQQWRRQRDLRRALDSSNLSLAKEQHLQKKYMNEV 359
Q + R+ + R +++ RQ R D +E Q++ + E+
Sbjct: 383 IQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIREL 439
Score = 32.3 bits (72), Expect = 0.72
Identities = 43/240 (17%), Positives = 100/240 (41%), Gaps = 34/240 (14%)
Query: 9 LRQDANLAKRRHAELCRQKRVFNARN-RIIGGDTEAWDVQVHDQKIKEATEKARHETFAA 67
+R+ + + ++ RQ+ ++ +I + E W ++KI+E EK + + +
Sbjct: 355 IREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWR---QEEKIREQEEKRQEKMWRQ 411
Query: 68 EMRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKKDLPARQS 127
E + ++ I E ++ R+ I + ++ Q E + R+
Sbjct: 412 EKKMREQDEKIREQEEEMWRQE--EKIRELEEMMQDQEEK----------------LREV 453
Query: 128 DNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTET 187
+ ++ MQ+ E+ + +K QE++ + W ++ + + EQ+ E ++ +
Sbjct: 454 EEKMQEEEEKMQE--QEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQE--EKMWRQE 509
Query: 188 RLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNLAEITNLL 247
+++ K ++ E R+ K + E +++EK QEQE L E+ L
Sbjct: 510 EKMWEQEEKMQEQEEKMQRQE--------EKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 51.2 bits (121), Expect = 1e-06
Identities = 65/299 (21%), Positives = 127/299 (42%), Gaps = 51/299 (17%)
Query: 42 EAWD--VQVHDQKIKEATEKARHETFAAEMRQNDKIMCILENRKKRDRKNLCRAINDFQQ 99
+ W+ +Q ++KI+E EK R + +MR+ +++M E + +R + + ++
Sbjct: 371 QEWEEKIQEQEEKIREQEEKIREQE--EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR 428
Query: 100 S----FQKPETRREFD--LSDPLALKKDLPARQSDNDVRNTISGMQ-------------- 139
++K E RE + + + +++ RQ + +R +
Sbjct: 429 QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 488
Query: 140 ----------KFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTETRL 189
K ++ HE++K +EE+ R+ +Q+ W R E+K E E
Sbjct: 489 QEEKIREQEEKMWRQEEKIHEQEKIREEEKRQ---EQEEMW---RQEEKIREQ--EEIWR 540
Query: 190 QFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESVERK---KQEKKQEQEDNLAEITNL 246
Q ++ + +K+ K K ++ + I E K ++EK +EQE+ + E
Sbjct: 541 QKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEK 600
Query: 247 LRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQE---KLRLQEEK 302
+R E Q+ G + QEQ E++R Q+++I+E K+R QEEK
Sbjct: 601 IREQ--EEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRR-QEEKIREQEKKIREQEEK 656
Score = 38.5 bits (88), Expect = 0.010
Identities = 55/226 (24%), Positives = 97/226 (42%), Gaps = 32/226 (14%)
Query: 132 RNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTETRLQF 191
RNTI+ ++ ++ E+ + E + E L K + + + A+ L + +LQ
Sbjct: 272 RNTITD-EELKEKNAKLQEKLQLVESEKSEIQLNV----KELKRKLERAKLLLPQQQLQA 326
Query: 192 --DETAKHLQKLESTTRKAVCASV-----------KDFNKSQAIESVERK---KQEKKQE 235
D K LQ + + + V + K + + + I+ E K ++EK +E
Sbjct: 327 EADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE 386
Query: 236 QEDNLAEITNLLRGD-----LLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIR-LVQK 289
QE+ + E +R E ++ R + M E+ E+IR L +K
Sbjct: 387 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 446
Query: 290 QQIQEKLRLQEEKRQRDLDWDRRRIQGARATLLFERQQWRRQRDLR 335
QEK+R QEEKRQ + ++ R Q R E + WR++ +R
Sbjct: 447 MHEQEKIREQEEKRQEE---EKIREQEKRQEQ--EAKMWRQEEKIR 487
Score = 34.7 bits (78), Expect = 0.14
Identities = 59/268 (22%), Positives = 116/268 (43%), Gaps = 49/268 (18%)
Query: 50 DQKIKEATEKARHETFAAEMRQNDKIM---CILENRKKRDRKNLCRA---INDFQQSFQK 103
++KI+E EK R + RQ +KI I E K+++++ + R I + ++ +++
Sbjct: 483 EEKIREQEEKIREQE-EKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQ 541
Query: 104 PETRREFDLSDPLALKKDLPARQSDNDVRNTISGMQKFMG---EDLNFHERK-KFQEEQN 159
E E + +K + +D I ++ + E + E K + QEE+
Sbjct: 542 KEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKI 601
Query: 160 REWS-LQQQREWKNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKAVCASVKDFNK 218
RE + Q++E K E+K E E ++Q E + +++ E R+ + K
Sbjct: 602 REQEEMTQEQEEKMGEQEEKMCEQ---EEKMQ--EQEEKMRRQEEKIREQEKKIREQEEK 656
Query: 219 SQAIESVERKKQEKKQEQEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQ 278
+ E + ++++EK EQE+ + E + Q
Sbjct: 657 IREQEEMMQEQEEKMWEQEEKMCEQEEKM------------------------------Q 686
Query: 279 EQLEQIRLVQKQQIQEKLRL--QEEKRQ 304
EQ E++R +++ ++++RL QEEK Q
Sbjct: 687 EQEEKMRRQEEKMWEQEVRLRQQEEKMQ 714
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 50.8 bits (120), Expect = 2e-06
Identities = 61/301 (20%), Positives = 133/301 (44%), Gaps = 48/301 (15%)
Query: 42 EAWD--VQVHDQKIKEATEKARHETFAAEMRQNDKIMCILENRKKRDRKNLCRAINDFQQ 99
+ W+ +Q ++KI+E EK R + +MR+ +++M E + +R + +
Sbjct: 310 QEWEEKIQEQEEKIREQEEKIREQE--EKMRRQEEMMWEKEEKMRRQEEMM--------- 358
Query: 100 SFQKPETRREFDLSDPLALKKDLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQN 159
++K E R + + +K+ R+ + + E + E K+ +EE+
Sbjct: 359 -WEKEEKMRRLE---EMMWEKEEKIRELEEKMHEQ---------EKIREQEEKRQEEEKI 405
Query: 160 REWSLQQQREWKNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKAVCASVKDFNKS 219
RE +Q++E K R E+K E +K+ +K K +
Sbjct: 406 REQEKRQEQEAKMWRQEEKIRE---------------QEEKIREQEKKMWRQEEKIHEQE 450
Query: 220 QAIESVERKKQEKKQEQEDNLAEITNLLR-GDLLSENP---QQAASSFGPHRVVPDRWKG 275
+ E +R++QE+ QE+ + E + R + + E +Q + + D+ +
Sbjct: 451 KIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEK 510
Query: 276 MTQEQLEQIRLVQK-QQIQEKLRLQEEK--RQRDLDWDRRRIQGARATLLFERQQWRRQR 332
+ +++ + R +K ++ +EK+R QEEK Q ++ ++ G + + E+++ RRQ
Sbjct: 511 IREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQE 570
Query: 333 D 333
+
Sbjct: 571 E 571
Score = 38.5 bits (88), Expect = 0.010
Identities = 55/226 (24%), Positives = 97/226 (42%), Gaps = 32/226 (14%)
Query: 132 RNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTETRLQF 191
RNTI+ ++ ++ E+ + E + E L K + + + A+ L + +LQ
Sbjct: 211 RNTITD-EELKEKNAKLQEKLQLVESEKSEIQLNV----KELKRKLERAKLLLPQQQLQA 265
Query: 192 --DETAKHLQKLESTTRKAVCASV-----------KDFNKSQAIESVERK---KQEKKQE 235
D K LQ + + + V + K + + + I+ E K ++EK +E
Sbjct: 266 EADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE 325
Query: 236 QEDNLAEITNLLRGD-----LLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIR-LVQK 289
QE+ + E +R E ++ R + M E+ E+IR L +K
Sbjct: 326 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEK 385
Query: 290 QQIQEKLRLQEEKRQRDLDWDRRRIQGARATLLFERQQWRRQRDLR 335
QEK+R QEEKRQ + ++ R Q R E + WR++ +R
Sbjct: 386 MHEQEKIREQEEKRQEE---EKIREQEKRQEQ--EAKMWRQEEKIR 426
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 50.4 bits (119), Expect = 3e-06
Identities = 63/291 (21%), Positives = 129/291 (44%), Gaps = 21/291 (7%)
Query: 46 VQVHDQKIKEATEKARHETFAAEMRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPE 105
+Q ++KI+E EK R + +MR+ +++M E + +R + + ++K E
Sbjct: 297 IQEREEKIQEQEEKIREQE--EKMRRQEEMMWEKEEKMRRQEEMM----------WEKEE 344
Query: 106 TRREFD--LSDPLALKKDLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWS 163
RE + + + +++ RQ + +R Q+ + E+ + QEE+ RE
Sbjct: 345 KIRELEEKMHEQEKIREQEEKRQEEEKIREQ-EKRQEQEAKMWRQEEKIREQEEKIREQE 403
Query: 164 -LQQQREWKNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAI 222
+ Q++E K E+K E E +Q E + +++ E R+ + K +
Sbjct: 404 EMMQEQEEKMGEQEEKMWEQ---EEEMQ--EQEEKMRRQEEKIREQEKKIREQEEKIREQ 458
Query: 223 ESVERKKQEKKQEQEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLE 282
E + ++++EK EQE + E ++ Q+ ++ K QE++
Sbjct: 459 EEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 518
Query: 283 QIRLVQKQQIQEKLRLQEEKRQRDLDWDRRRIQGARATLLFERQQWRRQRD 333
Q + + + +EK+ QEEK Q + RR+ + R + RQQ + ++
Sbjct: 519 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 45.1 bits (105), Expect = 1e-04
Identities = 53/207 (25%), Positives = 93/207 (44%), Gaps = 15/207 (7%)
Query: 132 RNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTETRLQF 191
RNTI+ ++ ++ E+ + E + E L K + + + A+ L + +LQ
Sbjct: 199 RNTITD-EELKEKNAKLQEKLQLVESEKSEIQLNV----KELKRKLERAKLLLPQQQLQA 253
Query: 192 --DETAKHLQKLESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNLAEITNLLRG 249
D K LQ + + + V + +Q E +++EK QE+E+ + E +R
Sbjct: 254 EADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIRE 313
Query: 250 DLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIR-LVQKQQIQEKLRLQEEKRQRDLD 308
E ++ R + M E+ E+IR L +K QEK+R QEEKRQ +
Sbjct: 314 Q--EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE-- 369
Query: 309 WDRRRIQGARATLLFERQQWRRQRDLR 335
++ R Q R E + WR++ +R
Sbjct: 370 -EKIREQEKRQEQ--EAKMWRQEEKIR 393
Score = 43.5 bits (101), Expect = 3e-04
Identities = 62/304 (20%), Positives = 130/304 (42%), Gaps = 34/304 (11%)
Query: 48 VHDQKIKEATEKARHETFAAEMRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETR 107
+ D+++KE K + + E +++ + + E ++K +R L QQ Q
Sbjct: 202 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLP----QQQLQAEADH 257
Query: 108 REFDLSDPLALKKDLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQ 167
+L ++ L A+ +N++ N ++ Q E+ + + +K QE RE +Q+Q
Sbjct: 258 LGKELQ---SVSAKLQAQVEENELWNRLNQQQ----EEKMWRQEEKIQE---REEKIQEQ 307
Query: 168 REWKNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESVER 227
E K E+K + + + +++ K ++ E + K + I +E
Sbjct: 308 EE-KIREQEEK----MRRQEEMMWEKEEKMRRQEEMM-----------WEKEEKIRELEE 351
Query: 228 K--KQEKKQEQEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIR 285
K +QEK +EQE+ E + + E Q+A ++ K QE++ Q +
Sbjct: 352 KMHEQEKIREQEEKRQEEEKIREQEKRQE--QEAKMWRQEEKIREQEEKIREQEEMMQEQ 409
Query: 286 LVQKQQIQEKLRLQEEKRQRDLDWDRRRIQGARATLLFERQQWRRQRDLRRALDSSNLSL 345
+ + +EK+ QEE+ Q + RR+ + R R+Q + R+ + +
Sbjct: 410 EEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 469
Query: 346 AKEQ 349
+++
Sbjct: 470 GEQE 473
Score = 36.6 bits (83), Expect = 0.038
Identities = 47/220 (21%), Positives = 94/220 (42%), Gaps = 30/220 (13%)
Query: 150 ERKKFQEEQNREWSLQQQREWKNARAEQKC--AEALYTETRLQFDETAKHLQKLESTTRK 207
ER E R ++ + KNA+ ++K E+ +E +L E + L++ + +
Sbjct: 189 ERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ 248
Query: 208 AVCASVKDFNKSQAIESVERKKQEKKQEQEDNLAEITNLLRGDLLSENPQQAASSFGPHR 267
+ D + + ++SV K Q + +E E + N L N QQ +
Sbjct: 249 QQLQAEAD-HLGKELQSVSAKLQAQVEENE-----LWNRL-------NQQQEEKMWRQEE 295
Query: 268 VVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQEE---------KRQRDLDWDRRRIQGAR 318
+ +R + + QEQ E+IR + +EK+R QEE +RQ ++ W++
Sbjct: 296 KIQEREEKI-QEQEEKIR-----EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 349
Query: 319 ATLLFERQQWRRQRDLRRALDSSNLSLAKEQHLQKKYMNE 358
+ E+++ R Q + R+ + +++ K + E
Sbjct: 350 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 389
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 50.1 bits (118), Expect = 3e-06
Identities = 51/250 (20%), Positives = 117/250 (46%), Gaps = 23/250 (9%)
Query: 125 RQSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCAEALY 184
+Q D + +S +Q+ + ++ E K + +++ LQ Q+ + R +Q+ E L
Sbjct: 120 QQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQ-QEQLQ 178
Query: 185 TETRLQFDETAKHLQKLESTTRKA--VCASVKDFNKSQAIESVERKKQEKKQEQEDNLAE 242
T+ + Q + + ++L+ ++ + + + Q ++ E+ +Q++ Q+Q++ L +
Sbjct: 179 TQ-QAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQ 237
Query: 243 ITNLL----RGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRL 298
LL +G L + QQ + + + + Q L+Q +Q+QQ Q+ L+
Sbjct: 238 QQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQ 297
Query: 299 QEEKRQR--------------DLDWDRRRIQ-GARATLLFERQQWRRQRDLRRALDSSNL 343
Q+E+ Q+ +++ + + G+ L +RQ+ RQ++L R + L
Sbjct: 298 QQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQL 357
Query: 344 SLAKEQHLQK 353
L ++ LQ+
Sbjct: 358 QLKLQEELQQ 367
Score = 34.7 bits (78), Expect = 0.14
Identities = 38/203 (18%), Positives = 91/203 (44%), Gaps = 13/203 (6%)
Query: 149 HERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKA 208
H + Q +Q+ + L Q ++ K+ + L E +L + Q+++ R
Sbjct: 115 HLELQQQPQQDGQQQLSQLQQEKHQSVHH---QELKPELQLMHQQQQLQPQQVQEQQRLQ 171
Query: 209 VCASVKDFNKSQAIESVERKKQEKKQEQEDNLAEITN--LLRGDLLSENPQQAASSFGPH 266
++Q + +++++Q ++Q QE L + L + LL + Q F
Sbjct: 172 QQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQF--- 228
Query: 267 RVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQRDLDWDRRRIQGARATLLFERQ 326
+ + Q+Q + + L Q+ Q+Q++L Q++ + + ++++ Q + LL ++Q
Sbjct: 229 ----QQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQ-LQQQLLLQQQ 283
Query: 327 QWRRQRDLRRALDSSNLSLAKEQ 349
+ +Q+ ++ L L ++Q
Sbjct: 284 EQLQQQQQQQLLQQQQEQLQQQQ 306
Score = 33.1 bits (74), Expect = 0.42
Identities = 30/139 (21%), Positives = 64/139 (46%), Gaps = 15/139 (10%)
Query: 222 IESVERKKQEKKQEQEDNLAEITNLLRGDLLSENPQQAASSF------GPHRVVPDRWKG 275
++ +E++ + ++Q Q + L + L L + PQQ H+ V +
Sbjct: 91 LQQLEQQPEPQQQPQHEQLQQPQPHLE---LQQQPQQDGQQQLSQLQQEKHQSVHHQELK 147
Query: 276 MTQEQLEQIRLVQKQQIQEKLRLQEEKRQRDLDWDRRRIQGARATLLFERQQWRRQRDLR 335
+ + Q + +Q QQ+QE+ RLQ+++ Q Q +L +++Q ++Q +
Sbjct: 148 PELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQ------QAQEQQVLQQQEQLQQQVQEQ 201
Query: 336 RALDSSNLSLAKEQHLQKK 354
+ L L ++Q LQ++
Sbjct: 202 QLLQQQQEQLQQQQLLQQQ 220
Score = 33.1 bits (74), Expect = 0.42
Identities = 33/163 (20%), Positives = 78/163 (47%), Gaps = 5/163 (3%)
Query: 155 QEEQNREWSLQQQREWKNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKAVCASVK 214
Q+EQ ++ QQQ+E +Q+ L + +LQ + +L+ + A ++
Sbjct: 219 QQEQLQQQQFQQQQEQLQ---QQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQ 275
Query: 215 DFNKSQAIESVERKKQEKKQEQEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWK 274
Q E +++++Q++ +Q+ + L L E ++ P + ++
Sbjct: 276 QQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQEL 335
Query: 275 GMTQEQLEQIRLVQKQQIQE--KLRLQEEKRQRDLDWDRRRIQ 315
+++LE+ + +++QQ Q +L+LQEE +Q + ++++ Q
Sbjct: 336 EQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQ 378
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 50.1 bits (118), Expect = 3e-06
Identities = 59/292 (20%), Positives = 119/292 (40%), Gaps = 52/292 (17%)
Query: 52 KIKEATEKARHETFAAEMRQNDKIMCILENRKK--RDRKNLCRAINDFQQSFQKPETRRE 109
+ KE K R + + ++ + + E +++ R ++ AI+ FQQ Q+ +
Sbjct: 153 RFKEEVTKERDQLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQNEAS 212
Query: 110 FDLSDPLALKKDLPARQSDNDVRNT-ISGMQKFMGED----------------LNFHERK 152
+ L+K+L Q+D D R T I +Q+++ + LN K
Sbjct: 213 REFRKKEKLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNERAAK 272
Query: 153 KFQEEQNREWSLQQQREWKNARAEQKCAEALYTETRLQFDETAKHLQKLE---------- 202
+ ++ Q R LQQ+ E + EQ E L+ E H +L+
Sbjct: 273 ELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQ 332
Query: 203 -------STTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNLAEITNLLRGDLLSEN 255
+ +KA K+ K+Q + + KKQ + D A L D+L++N
Sbjct: 333 IHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKN 392
Query: 256 PQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQ--KQQIQEKLRLQEEKRQR 305
+A ++ TQ+Q + ++L + K+ ++ +++ +++ Q+
Sbjct: 393 MLKAVNA--------------TQKQTDLVKLHEQAKRNLEGEIQNYKDEAQK 430
Score = 28.9 bits (63), Expect = 7.9
Identities = 61/348 (17%), Positives = 137/348 (39%), Gaps = 30/348 (8%)
Query: 19 RHAELCRQKRVFNARNRIIGGDTEAWDVQVHDQKIKEATEKARHETFAAEMRQNDKIMCI 78
+H+ +C Q N + + + +A + +VH ++ E ++ +
Sbjct: 290 QHSLVCEQLSQENQQKAL---ELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAE 346
Query: 79 LENRKKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKKDLPARQSDNDVRNTISGM 138
+E K+ + + + + S ++ E R+ D L ++D+ + ++ ++
Sbjct: 347 VEQHKETLKNQIVGLEREVEASKKQAELDRK--AMDELLRERDI----LNKNMLKAVNAT 400
Query: 139 QKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTETRLQFDETAKHL 198
QK + + HE+ K +N E +Q ++ A+ ++K L E ++ +
Sbjct: 401 QK-QTDLVKLHEQAK----RNLEGEIQNYKD--EAQKQRKIIFHLEKERDRYINQASDLT 453
Query: 199 QKLESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNLAEITNLLRGDLLSENPQQ 258
QK+ + F+ + I + E K +Q+ NL E R +L S+N +
Sbjct: 454 QKVLMNMEDIKVRETQIFDYRKKIA-----ESEIKLKQQQNLYEAVRSDR-NLYSKNLVE 507
Query: 259 AASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQ---EKLRLQEEKRQRDLDWDRRRIQ 315
A + E E I + ++ E+ R+++EK + + R Q
Sbjct: 508 AQDEITDMKRKLKIMIHQVDELKEDISAKESALVKLHLEQQRIEKEKETLKAELQKLRQQ 567
Query: 316 GARATLLFERQQWRRQRDLRRALDSSNLSLAKEQHLQKKYMNEVYTNQ 363
E+Q+ ++ LR ++ E+ QKK +++V + +
Sbjct: 568 ALETKHFIEKQEAEERKLLRIIAEADG-----ERLRQKKELDQVISER 610
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 49.7 bits (117), Expect = 4e-06
Identities = 62/303 (20%), Positives = 128/303 (42%), Gaps = 41/303 (13%)
Query: 42 EAWD--VQVHDQKIKEATEKARHETFAAEMRQNDKIMCILENRKKRDRKNLCRAINDFQQ 99
+ W+ +Q ++KI+E EK R + +MR+ +++M E + +R + + ++
Sbjct: 310 QEWEEKIQEQEEKIREQEEKIREQE--EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR 367
Query: 100 S----FQKPETRREFDLSDPLALKKDLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQ 155
++K E R + + +K+ R+ + + E + E K+ +
Sbjct: 368 QEEMMWEKEEKMRR---QEEMMWEKEEKIRELEEKMHEQ---------EKIREQEEKRQE 415
Query: 156 EEQNREWSLQQQREWKNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKAVCASVKD 215
EE+ RE +Q++E K R E+K E +K+ +K K
Sbjct: 416 EEKIREQEKRQEQEAKMWRQEEKIRE---------------QEEKIREQEKKMWRQEEKI 460
Query: 216 FNKSQAIESVERKKQEKKQEQEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKG 275
+ + E +R++QE+ QE+ + E + R E + R +
Sbjct: 461 HEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWR---QKEKMHEQEEKIRKQEEKVWRQEE 517
Query: 276 MTQEQLEQIRLVQKQ--QIQEKLRLQEEK-RQRDLDWDRRRIQGARATLLFERQQWRRQR 332
+EQ E+IR +++ + +EK+R QEE R+ + ++ +I E + WR++
Sbjct: 518 KIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEE 577
Query: 333 DLR 335
+R
Sbjct: 578 KIR 580
Score = 39.7 bits (91), Expect = 0.004
Identities = 41/194 (21%), Positives = 88/194 (45%), Gaps = 21/194 (10%)
Query: 144 EDLNFHERKKFQEEQNREWSLQQQ-REWKNARAEQKCAEALYTETRLQFDETAKHLQKLE 202
ED + + +K +E++ + W +++ RE + R EQ+ E ++ + + E + +Q+ E
Sbjct: 569 EDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQE--EKMWKQEE-KIREQEEKIQEQE 625
Query: 203 STTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNLAEITNLLRGDLLSENPQQAASS 262
R + K + E + ++++EK EQE+ + E ++ + Q+
Sbjct: 626 EKIR-------EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678
Query: 263 FGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQRDLDWDRRRIQGARATLL 322
++ K QE++ Q + + + +EK+ QEEK Q + RR+
Sbjct: 679 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ--------- 729
Query: 323 FERQQWRRQRDLRR 336
E + W ++ LR+
Sbjct: 730 -EEKMWEQEVRLRQ 742
Score = 33.1 bits (74), Expect = 0.42
Identities = 55/240 (22%), Positives = 97/240 (40%), Gaps = 46/240 (19%)
Query: 132 RNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTETRLQF 191
RNTI+ ++ ++ E+ + E + E L K + + + A+ L + +LQ
Sbjct: 211 RNTITD-EELKEKNAKLQEKLQLVESEKSEIQLNV----KELKRKLERAKLLLPQQQLQA 265
Query: 192 --DETAKHLQKLESTTRKAVCASV-----------KDFNKSQAIESVERK---KQEKKQE 235
D K LQ + + + V + K + + + I+ E K ++EK +E
Sbjct: 266 EADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE 325
Query: 236 QEDNLAEITNLLRGD-------------------LLSENPQQAASSFGPHRVVPDRWKGM 276
QE+ + E +R E ++ R + M
Sbjct: 326 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM 385
Query: 277 TQEQLEQIR-LVQKQQIQEKLRLQEEKRQRDLDWDRRRIQGARATLLFERQQWRRQRDLR 335
E+ E+IR L +K QEK+R QEEKRQ + ++ R Q R E + WR++ +R
Sbjct: 386 MWEKEEKIRELEEKMHEQEKIREQEEKRQEE---EKIREQEKRQEQ--EAKMWRQEEKIR 440
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 48.5 bits (114), Expect = 1e-05
Identities = 56/324 (17%), Positives = 139/324 (42%), Gaps = 49/324 (15%)
Query: 46 VQVHDQKIKEATEKARHETFAAE----MRQNDKIMCILENRKKRDRKNLCRAINDFQQSF 101
+Q ++K ++ EK + E E MR+ ++ M E + ++ +N+ Q
Sbjct: 432 MQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQ 491
Query: 102 QKPETRREFDLSDPLALKKDLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNRE 161
+ PE + + + + +++ Q + I ++ G++ ++K +E++++
Sbjct: 492 RLPEQKEKLWEQEKMQEQEEKIWEQEEK-----IRDQEEMWGQEKKMWRQEKMREQEDQM 546
Query: 162 WSL------QQQREW-KNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKAVCASVK 214
W Q+Q+ W + R E+K E + + +D+ K ++ R+
Sbjct: 547 WEQEEKMRDQEQKMWDQEERMEKKTQE----QEKKTWDQEEKMREEERMRERE------- 595
Query: 215 DFNKSQAIESVERKKQEKKQEQEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWK 274
K + E + R+++EK QEQE+ + E Q + + ++ +
Sbjct: 596 --KKMREEEEMMREQEEKMQEQEEKMQE---------------QEEKMWEQEEKMQEQEE 638
Query: 275 GMTQEQLEQIRLVQKQQIQEKLRLQEEKRQRDLDWDRRRIQGARATLLFERQQWRRQRDL 334
M ++ E+ Q++++ E+ RL E+K + W+ ++Q E + W +++
Sbjct: 639 KMWEQ--EEKMWEQEEKMWEQQRLPEQKEKL---WEHEKMQEQEKMQEQEEKIWEQEKME 693
Query: 335 RRALDSSNLSLAKEQHLQKKYMNE 358
++ + + +E+ +++ M E
Sbjct: 694 KKTQEQEKKTWDQEKMREEESMRE 717
Score = 47.4 bits (111), Expect = 2e-05
Identities = 63/328 (19%), Positives = 137/328 (41%), Gaps = 31/328 (9%)
Query: 10 RQDANLAKRRHAELCRQKRVFNARNRIIGGDTEAWDVQVHDQKIKEATEKARHETFAAEM 69
+Q+ N+ ++ E +Q+R+ + ++ E +Q ++KI E EK R + EM
Sbjct: 475 KQEENMWEQEEKEW-QQQRLPEQKEKL----WEQEKMQEQEEKIWEQEEKIRDQE---EM 526
Query: 70 RQNDKIMCILENRKKRDRK--NLCRAINDFQQSFQKPETRREFDLSDPLALKKDLPARQS 127
+K M E ++++ + + D +Q E R E + KK +
Sbjct: 527 WGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQE--KKTWDQEEK 584
Query: 128 DNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTET 187
+ +K E+ E+++ +EQ + Q+++ W+ Q+ E ++ +
Sbjct: 585 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQE 644
Query: 188 RLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNLAEITNLL 247
+++ K ++ + K + E + ++QEK QEQE+ + E +
Sbjct: 645 EKMWEQEEKMWEQQRLPEQ-----------KEKLWEHEKMQEQEKMQEQEEKIWEQEKME 693
Query: 248 RGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQRDL 307
+ E + +R K M +E+ E +R + +EK++ QEEK Q
Sbjct: 694 KKTQEQEKKTWDQEKMREEESMREREKKMREEE-EMMR-----EQEEKMQEQEEKMQEQE 747
Query: 308 D--WDRRRIQGARATLLFERQQWRRQRD 333
+ W++ + ++E+Q+ Q++
Sbjct: 748 EEMWEQEEKMWEQEEKMWEQQRLPEQKE 775
Score = 42.7 bits (99), Expect = 5e-04
Identities = 58/321 (18%), Positives = 134/321 (41%), Gaps = 33/321 (10%)
Query: 40 DTEAWDVQV---HDQKIKEATEKARHETFAAEMRQNDKIMCILENRKKRDRKNLCRAIND 96
+ + WD + +++++E +K R E MR+ ++ M E + + + +
Sbjct: 575 EKKTWDQEEKMREEERMREREKKMREEE--EMMREQEEKMQEQEEKMQEQEEKMWEQEEK 632
Query: 97 FQQSFQKPETRRE--FDLSDPLALKKDLPARQSDNDVRNTISGMQKFMGEDLNFHER--- 151
Q+ +K + E ++ + + ++ LP ++ + +K ++ E+
Sbjct: 633 MQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKM 692
Query: 152 -KKFQEEQNREWSLQQQREWKNARAEQKC---AEALYTETRLQFDETAKHLQKLE----S 203
KK QE++ + W ++ RE ++ R +K E + E + E + +Q+ E
Sbjct: 693 EKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWE 752
Query: 204 TTRKAVCASVKDFNKSQAIESVER-------KKQEKKQEQEDNLAEITNLLRGDLLSENP 256
K K + + + E E+ ++QEK EQE+ + + +RG
Sbjct: 753 QEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRG 812
Query: 257 QQAASSFGPHRVVPDRWKGMTQEQ----LEQIRLVQKQQIQEKLRLQEEKRQRDLDWDRR 312
Q+ ++ K QE+ E+ Q+++++EK++ QEEK +
Sbjct: 813 QEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMRE----QEE 868
Query: 313 RIQGARATLLFERQQWRRQRD 333
+++G + + ++ R Q +
Sbjct: 869 KMRGQEEKMREQEEKMRGQEE 889
Score = 42.0 bits (97), Expect = 0.001
Identities = 72/368 (19%), Positives = 150/368 (40%), Gaps = 59/368 (16%)
Query: 9 LRQDANLAKRRHAELCRQKRVFNARNRIIGGDTEAWDVQVHDQKIKEATEKA-RHETFAA 67
LR+ + + EL QK + ++ + + W+ ++K++E EK R E
Sbjct: 323 LREQEKELREQEKELREQKELREQEEQMQEQEEKMWE---QEEKMREQEEKMWRQEERLW 379
Query: 68 E----MRQNDKIMCILENR------KKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLA 117
E MR+ ++ M E R + R+++ R + +K R E + +
Sbjct: 380 EQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEK--MREEKKMQEQEK 437
Query: 118 LKKDLPAR-QSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARA- 175
+D + Q + +R M++ E+ + +K Q+++ W Q+++EW+ R
Sbjct: 438 KTRDQEEKMQEEERIREREKKMRE--EEETMREQEEKMQKQEENMWE-QEEKEWQQQRLP 494
Query: 176 EQKCAEALYTETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESVERKKQEKKQE 235
EQK E L+ + ++Q E +K+ K ++D + E + +QEK +E
Sbjct: 495 EQK--EKLWEQEKMQEQE-----EKIWEQEEK-----IRDQEEMWGQEK-KMWRQEKMRE 541
Query: 236 QEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEK 295
QED + E +R K QE+ R+ +K Q QEK
Sbjct: 542 QEDQMWEQEEKMRDQ---------------------EQKMWDQEE----RMEKKTQEQEK 576
Query: 296 LRLQEEKRQRDLDWDRRRIQGARATLLFERQQWRRQRDLRRALDSSNLSLAKEQHLQKKY 355
+E++ R+ + R R + R R+Q + ++ + + +++ ++
Sbjct: 577 KTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQ 636
Query: 356 MNEVYTNQ 363
+++ +
Sbjct: 637 EEKMWEQE 644
Score = 38.9 bits (89), Expect = 0.008
Identities = 46/218 (21%), Positives = 94/218 (43%), Gaps = 15/218 (6%)
Query: 150 ERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKAV 209
+ KK ++++ + W +++ + + ++ + E RL+ E Q+ E +K +
Sbjct: 284 QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKEL 343
Query: 210 CASVKDFNKSQAI----ESVERKKQEKKQEQEDNLAEITNLLRGDLLSENPQQAASSFGP 265
+ + + E R+++EK QE+ L E +R Q+
Sbjct: 344 REQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQD 403
Query: 266 HRVVPDRWKGMTQE----QLEQIRLVQKQQIQE-KLRLQEEKRQRDLDWDRRRIQGARAT 320
R+ + QE Q+E++R +K Q QE K R QEEK Q + RI+ R
Sbjct: 404 ERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQ-----EEERIR-EREK 457
Query: 321 LLFERQQWRRQRDLRRALDSSNLSLAKEQHLQKKYMNE 358
+ E ++ R+++ + N+ +E+ Q++ + E
Sbjct: 458 KMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPE 495
>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
Length = 1235
Score = 48.1 bits (113), Expect = 1e-05
Identities = 57/232 (24%), Positives = 111/232 (47%), Gaps = 35/232 (15%)
Query: 145 DLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTETRLQFDETAKHLQKLEST 204
+L F ++++ + +Q LQQQRE R EQ+ + Q+D+ ++L+K +
Sbjct: 833 ELRFLQKEEQRAQQQLNSKLQQQREQIFRRFEQE-----MMSKKRQYDQEIENLEKQQKQ 887
Query: 205 TRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNLAEITNLLRG---DLLSENPQQAAS 261
T + + + + + + + K EQE L++ N+L+ ++++E +
Sbjct: 888 TIERL--------EQEHTNRLRDEAKRIKGEQEKELSKFQNMLKNRKKEVINEVEK---- 935
Query: 262 SFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQRDLDWDRRR-IQGARAT 320
P + + K +E L Q Q QE+ +Q K+Q++LD ++ IQ +A
Sbjct: 936 --APKELRKELMKRRKEE------LAQSQHAQEQEFVQ--KQQQELDGSLKKIIQQQKAE 985
Query: 321 LL-FERQQWRRQRDLRRALDSSNLSLAKEQHLQKKYMNEVYTNQPTGDYFTQ 371
L ER+ ++ L RA +++ L +E+HLQ+K+ ++ Q YF Q
Sbjct: 986 LANIERECLNNKQQLMRAREAAIWEL-EERHLQEKH--QLLKQQLKDQYFMQ 1034
>gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens]
Length = 1080
Score = 47.8 bits (112), Expect = 2e-05
Identities = 68/314 (21%), Positives = 137/314 (43%), Gaps = 55/314 (17%)
Query: 51 QKIKE---ATEKARHETFAAEMRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETR 107
+K+KE ATEKAR E + +E + K + + + +K + R K E R
Sbjct: 675 KKLKELMSATEKARREKWISEKTKKIKEVTV-RGLEPEIQKLIAR---------HKQEVR 724
Query: 108 REFDLSDPLALKKDLPARQ----SDNDVRNTISGMQKFMGEDLNFHERKKFQEE-QNREW 162
R L + L+ D A Q ++R + ++ +G+ R++FQ+ + +W
Sbjct: 725 RLKSLHEAELLQSDERASQRCLRQAEELREQLEREKEALGQQERERARQRFQQHLEQEQW 784
Query: 163 SLQQQRE--WKNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQ 220
+LQQQR+ + E++ R + +E + L++ S +A+ A +F K
Sbjct: 785 ALQQQRQRLYSEVAEERERLGQQAARQRAELEELRQQLEESSSALTRALRA---EFEKG- 840
Query: 221 AIESVERKKQEKKQEQEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQ 280
R++QE++ + E N L+ L E +QA W+ +
Sbjct: 841 ------REEQERRHQME------LNTLKQQL--ELERQA-------------WEAGRTRK 873
Query: 281 LEQIRLVQKQQIQEKLRLQEEKRQRDLDWDRRRIQGARATLLFERQQWRRQRDLRRALDS 340
E L ++Q+++E++R + R ++++ R++ A L E + + ++R D
Sbjct: 874 EEAWLLNREQELREEIR---KGRDKEIELVIHRLE-ADMALAKEESEKAAESRIKRLRDK 929
Query: 341 SNLSLAKEQHLQKK 354
L++ + ++K
Sbjct: 930 YEAELSELEQSERK 943
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 46.6 bits (109), Expect = 4e-05
Identities = 72/357 (20%), Positives = 145/357 (40%), Gaps = 41/357 (11%)
Query: 8 DLRQDANLAKRRHAELCRQKRVFNARNRIIGGDTEAWDVQVHDQKIKEATEKARHETFAA 67
+L + AKR A L + K+ N+ + A +V+V Q++K +E R + A
Sbjct: 1207 ELSEQLEQAKRFKANLEKNKQGLETDNKEL-----ACEVKVL-QQVKAESEHKRKKLDAQ 1260
Query: 68 EMRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKKDLPARQS 127
+ K+ + R R L + Q T E + KD A
Sbjct: 1261 VQELHAKV-----SEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKD--AASL 1313
Query: 128 DNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQRE---WKNARAEQKCAEALY 184
++ +++T +Q+ + LN R + EE+ QQ+ E KN + ++
Sbjct: 1314 ESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQL 1373
Query: 185 TETRLQFDETAKHLQKLESTTRK----AVCASVKDFNKSQAIESVERKKQEKKQEQEDNL 240
+T+ + D+ ++ LE +K A S + K+ A + +E+ K +QE +D
Sbjct: 1374 ADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLT 1433
Query: 241 AEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQE 300
++ ++ +Q AS+ ++ + + L + + + + +E+ R +
Sbjct: 1434 VDL----------DHQRQVASNL-------EKKQKKFDQLLAEEKSISARYAEERDRAEA 1476
Query: 301 EKRQRD---LDWDRRRIQGARATLLFERQQWRRQRDLRRALDSSNLSLAKEQHLQKK 354
E R+++ L R + A FERQ + + D+ + S + + K H +K
Sbjct: 1477 EAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKD-DVGKNVHELEK 1532
Score = 38.5 bits (88), Expect = 0.010
Identities = 81/370 (21%), Positives = 144/370 (38%), Gaps = 57/370 (15%)
Query: 2 AVALPRDLRQDANLAKRRHAELCRQKRVFNARNRIIGGDTEAW-----DV--QVHD-QKI 53
A A R+ A R E K F +N+ + D E DV VH+ +K
Sbjct: 1474 AEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKS 1533
Query: 54 KEATEKARHETFAAEMRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETRREFDLS 113
K A E+ + E ++ + + + E+ K R N+ F++ Q + + E
Sbjct: 1534 KRALEQ-QVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKR 1592
Query: 114 DPLALKKDLPARQSDNDVRNTIS-GMQKFMGEDLNFHERKKFQEEQNREWSLQQ----QR 168
+ ++L A D + ++ +K M DL E + + R+ ++Q Q
Sbjct: 1593 LLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQA 1652
Query: 169 EWKNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESVERK 228
+ K+ + E + A A E Q E+ K L+ LE+ + + + S ER
Sbjct: 1653 QMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQL----------QEELASSERA 1702
Query: 229 KQEKKQEQEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQ 288
++ +QE+++ EITN G L++ R ++
Sbjct: 1703 RRHAEQERDELADEITNSASG---------------------------KSALLDEKRRLE 1735
Query: 289 KQQIQEKLRLQEEKRQRDLDWDRRR-----IQGARATLLFERQQWRRQRDLRRALDSSNL 343
+ Q + L+EE+ +L DR R + A L ER ++ + R+ L+ N
Sbjct: 1736 ARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNK 1795
Query: 344 SL-AKEQHLQ 352
L AK Q L+
Sbjct: 1796 ELKAKLQELE 1805
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 46.2 bits (108), Expect = 5e-05
Identities = 67/333 (20%), Positives = 149/333 (44%), Gaps = 40/333 (12%)
Query: 9 LRQDANLAKRRHAELCRQKRVFNARNRIIGGDTEAWDVQVHDQKIKEATEKARHETFAAE 68
LR+ + + EL QK++ ++ + + W+ ++K++E EK
Sbjct: 285 LREQEKELREQEKELREQKKLREQEEQMQEQEEKMWE---QEEKMREQEEKM-------- 333
Query: 69 MRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETRREFD--LSDPLALKKDLPARQ 126
RQ +++ ++K+ R+ + + ++ +++ E RE + + + + + Q
Sbjct: 334 WRQEERLW----EQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQ 389
Query: 127 SDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARA-EQKCAEALYT 185
+ +R M++ E+ + +K Q+++ W Q+++EW+ R EQK E L+
Sbjct: 390 EEERIREREKKMRE--EEETMREQEEKMQKQEENMWE-QEEKEWQQQRLPEQK--EKLWE 444
Query: 186 ETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNLAEITN 245
+ ++Q E +K+ K ++D + E + +QEK +EQED + E
Sbjct: 445 QEKMQEQE-----EKIWEQEEK-----IRDQEEMWGQEK-KMWRQEKMREQEDQMWEQEE 493
Query: 246 LLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQE-----QLEQIRLVQKQQIQEKLRLQE 300
+R D + Q + + ++ + M ++ Q E++R +K Q QEK +
Sbjct: 494 KMR-DQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQ 552
Query: 301 EKRQRDLDWDRRRIQGARATLLFERQQWRRQRD 333
E++ R+ + R R + R R+Q + ++
Sbjct: 553 EEKMREEERMREREKKMREEEEMMREQEEKMQE 585
Score = 45.4 bits (106), Expect = 8e-05
Identities = 54/288 (18%), Positives = 132/288 (45%), Gaps = 33/288 (11%)
Query: 25 RQKRVFNARNRIIGGDTEAWDVQVH----DQKIKEATEKARHETFAAEMRQNDKIMCILE 80
++ +++ ++ + + WD + D++++E E+ R + +M Q ++ M +
Sbjct: 484 QEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQK---KMWQQEEKMREEK 540
Query: 81 NRKKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKKDLPARQSDNDVRNTISGMQK 140
+++++K D ++ ++ E RE + +++ R+ + ++ M++
Sbjct: 541 KTQEQEKKTW-----DQEEKMREEERMRE---REKKMREEEEMMREQEEKMQEQEEKMRE 592
Query: 141 FMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQ-KCAEALYTETRLQFDETAKHLQ 199
E+ + + +K QE++ + W Q+++ W+ ++ + E + E + E + +
Sbjct: 593 --QEEKMWEQEEKMQEQEEKMWE-QEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMW 649
Query: 200 KLESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNLAEITNLLRGDLLSENPQQA 259
+ E R+ + K Q E R+++EK Q QE+ + E +RG Q
Sbjct: 650 EQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRG--------QE 701
Query: 260 ASSFGPHRVVPDRWKGM-----TQEQLEQIRLVQKQQIQEKLRLQEEK 302
+G + + + M +E+ E+IR QK+++QE+L EE+
Sbjct: 702 EKMWGQEEKMWGQEEKMWGQEEMREKEERIR-DQKEKMQERLPEHEER 748
Score = 43.9 bits (102), Expect = 2e-04
Identities = 66/328 (20%), Positives = 143/328 (43%), Gaps = 36/328 (10%)
Query: 10 RQDANLAKRRHAELCRQKRVFNARNRIIGGDTEAWDVQVHDQKIKEATEKARHETFAAEM 69
+Q+ N+ ++ E +Q+R+ + ++ E +Q ++KI E EK R + EM
Sbjct: 417 KQEENMWEQEEKEW-QQQRLPEQKEKL----WEQEKMQEQEEKIWEQEEKIRDQE---EM 468
Query: 70 RQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKKDLPARQSDN 129
+K M E ++++ + Q+ + + ++ +D + + ++D R+ +
Sbjct: 469 WGQEKKMWRQEKMREQEDQMW------EQEEKMRDQEQKMWDQEERM-WEQDERLREKEE 521
Query: 130 DVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQ-REWKNARAEQKCAEALYTETR 188
+R +K ++ E KK QE++ + W +++ RE + R +K E
Sbjct: 522 RMRE----QKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMR----EEE 573
Query: 189 LQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESVERKKQEK--KQEQEDNLAEITNL 246
E + +Q+ E R+ + K Q E +++EK +QE+ED + E
Sbjct: 574 EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQE---- 629
Query: 247 LRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQRD 306
+ +++ E ++ ++ + ++ EQ +Q Q+ EK+R QEEK Q
Sbjct: 630 -QEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQE--EKMREQEEKMQGQ 686
Query: 307 LDWDRRRIQGARATLLFERQQWRRQRDL 334
+ R + + R E + W ++ +
Sbjct: 687 EEKMREQEEKMRGQ---EEKMWGQEEKM 711
Score = 34.7 bits (78), Expect = 0.14
Identities = 43/198 (21%), Positives = 89/198 (44%), Gaps = 28/198 (14%)
Query: 150 ERKKFQEEQNREWSLQQQREWKNARAEQKC--AEALYTETRLQFDETAKHLQKLESTTRK 207
ER E R ++ + KNA ++K AE+ +E +L E + L++ + +
Sbjct: 167 ERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQ 226
Query: 208 AVCASVKDFNKSQAIESVE-----RKKQEKKQEQEDNLAEITNLLRGDLLSENPQQAASS 262
++++ Q E E RK++EK QE+ L E +R E ++
Sbjct: 227 VQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMR-----EQEEKMR-- 279
Query: 263 FGPHRVVPDRWKGMTQEQLEQIRLVQKQ-QIQEKLRLQEEKRQRDLD--WDRRRIQGARA 319
R + +EQ +++R +K+ + Q+KLR QEE+ Q + W++ +
Sbjct: 280 ---------RQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQE 330
Query: 320 TLLFERQQ--WRRQRDLR 335
++ +++ W +++ +R
Sbjct: 331 EKMWRQEERLWEQEKQMR 348
>gi|30794488 kinesin family member 27 [Homo sapiens]
Length = 1401
Score = 46.2 bits (108), Expect = 5e-05
Identities = 76/343 (22%), Positives = 123/343 (35%), Gaps = 61/343 (17%)
Query: 30 FNARNRIIGGDTEAWDVQVH-------DQKIKEATEKARHETFAAEMRQNDKIMCILENR 82
F R++++ G E D +H D + E EK+ + Q +C L
Sbjct: 620 FRTRSQMLLGHIEEQDKVLHCQFSDNSDDEESEGQEKSGTRCRSRSWIQKPDSVCSLVE- 678
Query: 83 KKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKKDLPARQSDNDVRNTISGMQKFM 142
++D Q QK + E D L ++L ++ N R QK
Sbjct: 679 -----------LSDTQDETQKSDLENEDLKIDCLQESQELNLQKLKNSERILTEAKQKMR 727
Query: 143 GEDLNFHERKKFQEEQ----NREWSLQQQREWKNARAEQKCAEALYTETRLQFDETAKHL 198
+N ++ +E N S+ +Q K + E +A +++ ET K L
Sbjct: 728 ELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQA-----KVELIETQKQL 782
Query: 199 QKLESTTRKAVCASVK---DFNKSQAIESVERKKQEKKQEQEDNLAEITNLLRGDLLSEN 255
Q+LE+ V VK +F K + + +KKQ+ LA ++
Sbjct: 783 QELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLS----------- 831
Query: 256 PQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQRDLDWDRRRIQ 315
+ + + EQ QK Q+Q KLR + EKR + LD +R Q
Sbjct: 832 -------------IQNEKRANELEQSVDHMKYQKIQLQRKLREENEKR-KQLDAVIKRDQ 877
Query: 316 GARATLLFERQQWRRQRDLRRALDSSNL-----SLAKEQHLQK 353
+ + Q + LD+ NL S HLQK
Sbjct: 878 QKIKEIQLKTGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQK 920
>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
Length = 1139
Score = 44.7 bits (104), Expect = 1e-04
Identities = 52/241 (21%), Positives = 106/241 (43%), Gaps = 28/241 (11%)
Query: 115 PLALKKDLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNAR 174
P K++ R D+ + ++ ED + K +E + + L+Q +EWK+
Sbjct: 77 PSPSKEEEGLRAQVRDLEEKLETLRLKRAED-----KAKLKELEKHKIQLEQVQEWKSKM 131
Query: 175 AEQKC-AEALYTETRLQFDETAKHLQK-LESTTRKAVCASVKDFNKSQAIESVERKKQEK 232
EQ+ + E R + E + ++ +E A + +K A E E +QE
Sbjct: 132 QEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEV 191
Query: 233 K--QEQEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQ 290
+ +E+ D L +L+ ++ + AASS+ ++ + ++ L ++R +
Sbjct: 192 EALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQL--EEQNARLKDALVRMRDLSSS 249
Query: 291 QIQEKLRLQE--EKRQRDLDWDRRRIQGARATLLFERQQWRRQRDLRRALDSSNLSLAKE 348
+ QE ++LQ+ EK+ ++L+ + +Q+ R Q +L +A S + KE
Sbjct: 250 EKQEHVKLQKLMEKKNQELE-------------VVRQQRERLQEELSQA--ESTIDELKE 294
Query: 349 Q 349
Q
Sbjct: 295 Q 295
>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
Length = 1253
Score = 44.7 bits (104), Expect = 1e-04
Identities = 52/241 (21%), Positives = 106/241 (43%), Gaps = 28/241 (11%)
Query: 115 PLALKKDLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNAR 174
P K++ R D+ + ++ ED + K +E + + L+Q +EWK+
Sbjct: 191 PSPSKEEEGLRAQVRDLEEKLETLRLKRAED-----KAKLKELEKHKIQLEQVQEWKSKM 245
Query: 175 AEQKC-AEALYTETRLQFDETAKHLQK-LESTTRKAVCASVKDFNKSQAIESVERKKQEK 232
EQ+ + E R + E + ++ +E A + +K A E E +QE
Sbjct: 246 QEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEV 305
Query: 233 K--QEQEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQ 290
+ +E+ D L +L+ ++ + AASS+ ++ + ++ L ++R +
Sbjct: 306 EALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQL--EEQNARLKDALVRMRDLSSS 363
Query: 291 QIQEKLRLQE--EKRQRDLDWDRRRIQGARATLLFERQQWRRQRDLRRALDSSNLSLAKE 348
+ QE ++LQ+ EK+ ++L+ + +Q+ R Q +L +A S + KE
Sbjct: 364 EKQEHVKLQKLMEKKNQELE-------------VVRQQRERLQEELSQA--ESTIDELKE 408
Query: 349 Q 349
Q
Sbjct: 409 Q 409
>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
Length = 1144
Score = 44.7 bits (104), Expect = 1e-04
Identities = 52/241 (21%), Positives = 106/241 (43%), Gaps = 28/241 (11%)
Query: 115 PLALKKDLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNAR 174
P K++ R D+ + ++ ED + K +E + + L+Q +EWK+
Sbjct: 77 PSPSKEEEGLRAQVRDLEEKLETLRLKRAED-----KAKLKELEKHKIQLEQVQEWKSKM 131
Query: 175 AEQKC-AEALYTETRLQFDETAKHLQK-LESTTRKAVCASVKDFNKSQAIESVERKKQEK 232
EQ+ + E R + E + ++ +E A + +K A E E +QE
Sbjct: 132 QEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEV 191
Query: 233 K--QEQEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQ 290
+ +E+ D L +L+ ++ + AASS+ ++ + ++ L ++R +
Sbjct: 192 EALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQL--EEQNARLKDALVRMRDLSSS 249
Query: 291 QIQEKLRLQE--EKRQRDLDWDRRRIQGARATLLFERQQWRRQRDLRRALDSSNLSLAKE 348
+ QE ++LQ+ EK+ ++L+ + +Q+ R Q +L +A S + KE
Sbjct: 250 EKQEHVKLQKLMEKKNQELE-------------VVRQQRERLQEELSQA--ESTIDELKE 294
Query: 349 Q 349
Q
Sbjct: 295 Q 295
>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
Length = 1278
Score = 44.7 bits (104), Expect = 1e-04
Identities = 52/241 (21%), Positives = 106/241 (43%), Gaps = 28/241 (11%)
Query: 115 PLALKKDLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNAR 174
P K++ R D+ + ++ ED + K +E + + L+Q +EWK+
Sbjct: 211 PSPSKEEEGLRAQVRDLEEKLETLRLKRAED-----KAKLKELEKHKIQLEQVQEWKSKM 265
Query: 175 AEQKC-AEALYTETRLQFDETAKHLQK-LESTTRKAVCASVKDFNKSQAIESVERKKQEK 232
EQ+ + E R + E + ++ +E A + +K A E E +QE
Sbjct: 266 QEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEV 325
Query: 233 K--QEQEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQ 290
+ +E+ D L +L+ ++ + AASS+ ++ + ++ L ++R +
Sbjct: 326 EALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQL--EEQNARLKDALVRMRDLSSS 383
Query: 291 QIQEKLRLQE--EKRQRDLDWDRRRIQGARATLLFERQQWRRQRDLRRALDSSNLSLAKE 348
+ QE ++LQ+ EK+ ++L+ + +Q+ R Q +L +A S + KE
Sbjct: 384 EKQEHVKLQKLMEKKNQELE-------------VVRQQRERLQEELSQA--ESTIDELKE 428
Query: 349 Q 349
Q
Sbjct: 429 Q 429
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 44.7 bits (104), Expect = 1e-04
Identities = 50/240 (20%), Positives = 105/240 (43%), Gaps = 11/240 (4%)
Query: 125 RQSDND-VRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCAEAL 183
RQ+D + R T QK + N ER++ + ++ +E + + + E++
Sbjct: 161 RQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETET 220
Query: 184 YTETRLQFDETAKHLQKLESTTRKAV---CASVKDFNKSQAIESV-----ERKKQEKKQE 235
TE + Q D +K E K AS ++ + + E +R +++K++E
Sbjct: 221 ETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERE 280
Query: 236 QEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEK 295
++ + R D +E ++ R + + + + E+ R + ++ +EK
Sbjct: 281 RQTDRKRQRRTER-DRETERKRERQRERERERERNRKRERERERERERERQRETERDREK 339
Query: 296 LRLQEEKRQRDLDWDRRRIQGARATLLFERQQWR-RQRDLRRALDSSNLSLAKEQHLQKK 354
R ++ KRQ ++D +R R G ER++ R R+RD + A + +++ QK+
Sbjct: 340 ERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKE 399
Score = 44.7 bits (104), Expect = 1e-04
Identities = 63/326 (19%), Positives = 130/326 (39%), Gaps = 33/326 (10%)
Query: 7 RDLRQDANLAKRRHAELCRQKRVFNARNRIIGGDTEAWDVQVHDQKIKEATEKARHETFA 66
R + + N K R E RQ+R R R TE H ++ +E + ET
Sbjct: 167 RQRQTERNRQKEREREKNRQERRERERQREKENKTE----DRHSERGRERERERETETET 222
Query: 67 AEMRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKKDLPARQ 126
RQ D+ + ++K +R+ +A ++ + ET R+ + +D RQ
Sbjct: 223 ERKRQTDRER---DRQRKTEREREKQAE---RERASERETERDKERERERDRDRDRDRRQ 276
Query: 127 SDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTE 186
+ + R T Q+ D +++ Q E+ RE ++RE + R ++ +
Sbjct: 277 KERE-RQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQR---- 331
Query: 187 TRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNLAEITNL 246
ET + +K RK ++ N+ E + ++E+++E+E +
Sbjct: 332 ------ETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARER 385
Query: 247 LRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQRD 306
+ + +Q + T++ + R +KQ+ +EK R E R+R
Sbjct: 386 EERERDRDRDRQKER------------ERQTEKDRDGQRETEKQREREKDRESERGRERG 433
Query: 307 LDWDRRRIQGARATLLFERQQWRRQR 332
+ ++++ + +RQ R+++
Sbjct: 434 REREKQKGRERDRERQTDRQAGRQRK 459
Score = 40.0 bits (92), Expect = 0.003
Identities = 52/252 (20%), Positives = 105/252 (41%), Gaps = 16/252 (6%)
Query: 82 RKKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKKDLPARQSDNDVRNTISGMQKF 141
+K+R+R+ R +++ +K E RRE D ++ + R T +
Sbjct: 59 QKERERRREKRQTE--RETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQ 116
Query: 142 MGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTETRLQFDETAKHLQKL 201
++ N + ++ + E+ E +Q + + R Q+ AE E Q D ++
Sbjct: 117 REKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEK---ERERQTDR-----ERQ 168
Query: 202 ESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNLAEITNLLRGDLLSENPQQAAS 261
T R ++ N+ + E +++EK+ + ED +E + +E +
Sbjct: 169 RQTERNRQKEREREKNRQERRE--RERQREKENKTEDRHSERGRERERERETETETERKR 226
Query: 262 SFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQRDLDWDRRRIQGARATL 321
R + + ++Q E+ R +++ ++K E +R+RD D DR R Q R
Sbjct: 227 QTDRERDRQRKTEREREKQAERERASERETERDK----ERERERDRDRDRDRRQKERERQ 282
Query: 322 LFERQQWRRQRD 333
++Q R +RD
Sbjct: 283 TDRKRQRRTERD 294
>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
[Homo sapiens]
Length = 1354
Score = 44.3 bits (103), Expect = 2e-04
Identities = 71/344 (20%), Positives = 148/344 (43%), Gaps = 38/344 (11%)
Query: 29 VFNARNRIIGGDTEA-WDVQVHDQKIKEATEKARH--ETFAAEMRQNDKIMCILENRKKR 85
+ A R G D+E D+Q ++E + +H E E ++ ++ N ++
Sbjct: 609 ILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDML----NHSEK 664
Query: 86 DRKNLCRAINDFQQSFQKPETRREFDLSDPLALKKDLPARQSDNDVRNTIS--GMQKFMG 143
++ NL +N +S Q+ R E ++++ K L + + +++ M+K +
Sbjct: 665 EKNNLEIDLNYKLKSLQQ---RLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLK 721
Query: 144 EDLNFHERKKFQEEQNREWSLQQQREWKNA---RAEQKCAEALYTETRLQFDETAKHLQK 200
E ER+ ++ +NR +++Q + +++QK + R++ DE +
Sbjct: 722 E-----EREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERME-DEVKNLTLQ 775
Query: 201 LESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDN-LAEITNLLRGDLLSENPQQA 259
LE + K + +++ K+QA E+ K EK+ +QE N L E LL + L++ +Q
Sbjct: 776 LEQESNKRLL--LQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFE-LAQLTKQY 832
Query: 260 ASSFGPHRVVPDR----------WKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQRDLDW 309
+ G R + D+ +K +E E+I ++ +++ LQ EK
Sbjct: 833 RGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQL 892
Query: 310 DRRRIQGARATL---LFERQQWRRQRDLRRALDSSNLSLAKEQH 350
D + L L E Q + ++ ++A + + + H
Sbjct: 893 DLAETKAESEQLARGLLEEQYFELTQESKKAASRNRQEITDKDH 936
Score = 34.3 bits (77), Expect = 0.19
Identities = 43/184 (23%), Positives = 82/184 (44%), Gaps = 27/184 (14%)
Query: 144 EDLNFHERKKFQEEQNREWSLQQQREWKNARAE-QKCAEALYTETRLQFDETAKHL---Q 199
E+ N KK QE QN + +L Q + +AE ++ A L E + + +K
Sbjct: 868 EEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELTQESKKAASRN 927
Query: 200 KLESTTRKAVCASVKDFNK--SQAIESVERKKQE-----KKQEQEDNL---AEITNLLRG 249
+ E T + + +++ N ++ IE + R+ +E KK E+E L EI+NL
Sbjct: 928 RQEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEEYKLEKEEEISNLKAA 987
Query: 250 DLLSENPQQAASSFGPHRVVP---------DRWKGMTQEQLEQIRLVQKQQIQEKLRLQE 300
+ N ++ + +++ DR K TQ+ +R +K+ + +L L +
Sbjct: 988 FEKNINTERTLKTQAVNKLAEIMNRKDFKIDRKKANTQD----LRKKEKENRKLQLELNQ 1043
Query: 301 EKRQ 304
E+ +
Sbjct: 1044 EREK 1047
>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 479
Score = 44.3 bits (103), Expect = 2e-04
Identities = 58/223 (26%), Positives = 103/223 (46%), Gaps = 28/223 (12%)
Query: 118 LKKDLPA--RQSDNDVRNT--ISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNA 173
L+K+L + RQ +V N +S + + E L E + ++E+ L +Q E
Sbjct: 169 LRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEER----LHEQEERLCE 224
Query: 174 RAEQKCAEA---LYTETRLQFDETAKHLQK---LESTTR-----KAVCASVKDFNKSQAI 222
+ E+ C + E RL+ E H Q+ E R + +C K + + +
Sbjct: 225 QEERLCEQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLL 284
Query: 223 ESVERK-KQEKKQEQEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQL 281
E VE+ +QE++QE+++ L E LL D + E +Q R+ W+ T +L
Sbjct: 285 EEVEKLLEQERRQEEQERLLERERLL--DEVEELLEQERLRQQDERL----WQQETLREL 338
Query: 282 EQIRLVQKQQIQEKLRLQEEKRQRDLDWDRRRIQGARATLLFE 324
E++R + ++++E RL+E +R +L W+ Q A FE
Sbjct: 339 ERLR--ELERLRELERLRELERMLELGWEALYEQRAEPRSGFE 379
>gi|126362971 serine/threonine kinase 10 [Homo sapiens]
Length = 968
Score = 44.3 bits (103), Expect = 2e-04
Identities = 63/309 (20%), Positives = 130/309 (42%), Gaps = 28/309 (9%)
Query: 42 EAWDVQVHDQKIKEATEKARHETFAAEMRQNDKIMCILENRKKRDRKNLCRAINDFQQS- 100
E + + D K+ + T K + + + I+ +K+D + + ++
Sbjct: 511 EMGSLSIKDPKLYKKTLKRTRKFVVDGVEVSITTSKIISEDEKKDEEMRFLRRQELRELR 570
Query: 101 -FQKPETRREFDLSDPLALKKDLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQ--EE 157
QK E R + LS+ K +L Q I+ +KF +L ER++ Q E+
Sbjct: 571 LLQKEEHRNQTQLSN----KHELQLEQMHKRFEQEINAKKKFFDTELENLERQQKQQVEK 626
Query: 158 QNREWSLQQQREWKNARAEQKCAEALYTET-RLQFDETAKHLQKLESTTRKAVCASVKDF 216
++ +++++ E + R EQ + E +L E ++KL RK
Sbjct: 627 MEQDHAVRRREEARRIRLEQDRDYTRFQEQLKLMKKEVKNEVEKLPRQQRKE-------- 678
Query: 217 NKSQAIESVERKKQEKKQEQEDNLAEITNLLRGDLLSENPQQAASS-----FGPHRVVPD 271
+ Q +E +KKQ ++ E L L ++N ++ ++ D
Sbjct: 679 SMKQKMEEHTQKKQLLDRDFVAKQKEDLELAMKRLTTDNRREICDKERECLMKKQELLRD 738
Query: 272 R----WKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQRDLDWDRRRIQGARATLLFERQQ 327
R W+ M + QL++ + KQQ++++ LQ + R + +R ++Q ++ E+ +
Sbjct: 739 REAALWE-MEEHQLQERHQLVKQQLKDQYFLQRHELLRKHEKEREQMQRYNQRMI-EQLK 796
Query: 328 WRRQRDLRR 336
R+Q++ R
Sbjct: 797 VRQQQEKAR 805
Score = 34.3 bits (77), Expect = 0.19
Identities = 42/177 (23%), Positives = 70/177 (39%), Gaps = 20/177 (11%)
Query: 196 KHLQKLESTTRKAVCASVK-DFNKSQAIESVERKKQEKKQEQEDNLAEITNLLRGDLLSE 254
K +K TRK V V+ S+ I E+K +E + + L E+ L + E
Sbjct: 521 KLYKKTLKRTRKFVVDGVEVSITTSKIISEDEKKDEEMRFLRRQELRELRLLQK----EE 576
Query: 255 NPQQAASSFGPHRVVPDRWKGMTQE----------QLEQIRLVQKQQIQEK-----LRLQ 299
+ Q S + K QE +LE + QKQQ+++ +R +
Sbjct: 577 HRNQTQLSNKHELQLEQMHKRFEQEINAKKKFFDTELENLERQQKQQVEKMEQDHAVRRR 636
Query: 300 EEKRQRDLDWDRRRIQGARATLLFERQQWRRQRDLRRALDSSNLSLAKEQHLQKKYM 356
EE R+ L+ DR + L +++ L R ++ E+H QKK +
Sbjct: 637 EEARRIRLEQDRDYTRFQEQLKLMKKEVKNEVEKLPRQQRKESMKQKMEEHTQKKQL 693
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 44.3 bits (103), Expect = 2e-04
Identities = 87/378 (23%), Positives = 157/378 (41%), Gaps = 60/378 (15%)
Query: 22 ELCRQKRVFNARNRII---GGDTEAWDVQVHDQKIKEATEKARHETFAAEMRQNDKIMCI 78
EL + K A NR + D +Q +K+K+ E+A + AA+ + ++ +
Sbjct: 2239 ELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQ--EAARLRQL 2296
Query: 79 LENRKKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKKDLPARQSDNDVRNTISGM 138
E + R + + + Q+ Q+ TR + + ++ L +K+L Q+ +
Sbjct: 2297 AEEDLAQQRALAEKMLKEKMQAVQEA-TRLKAE-AELLQQQKELAQEQARRLQEDKEQMA 2354
Query: 139 QKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTET----RLQFDET 194
Q+ E F + + ++ E S + +R K AE A+A E R Q +E
Sbjct: 2355 QQLAEETQGFQRTLEAERQRQLEMSAEAER-LKLRVAEMSRAQARAEEDAQRFRKQAEEI 2413
Query: 195 AKHLQKLE-STTRKAVCASVKDFNKSQ----------AIESVERKKQEKKQE-------- 235
+ L + E +T K + + Q AI +ER+K++ +QE
Sbjct: 2414 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2473
Query: 236 ------QEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQK 289
Q++ L + T L+ LSE S R + + EQL Q + +
Sbjct: 2474 EEMQTVQQEQLLQETQALQQSFLSEKD----SLLQRERFIEQEKAKL--EQLFQDEVAKA 2527
Query: 290 QQIQEKLRLQ----EEKRQR---DLDWDRRRIQGARATL------LFERQQWRRQRDLRR 336
QQ++E+ + Q E++RQR ++ RRR A + L + +Q RRQ++
Sbjct: 2528 QQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELL 2587
Query: 337 ALDS----SNLSLAKEQH 350
A ++ L L +EQH
Sbjct: 2588 AEENQRLREQLQLLEEQH 2605
Score = 38.9 bits (89), Expect = 0.008
Identities = 62/287 (21%), Positives = 127/287 (44%), Gaps = 51/287 (17%)
Query: 51 QKIKEATEKARHETFAAEMRQNDKIMCI--LENRKKR---DRKNLCRAINDFQQSFQKPE 105
Q+ ++ E+ + E+ +K+ + LE ++++ D + L AI + ++ +K +
Sbjct: 2404 QRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELER--EKEK 2461
Query: 106 TRREFDLSDPLALK-KDLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSL 164
++E L L LK +++ Q + ++ T + Q F+ E + +R++F E++ + L
Sbjct: 2462 LQQEAKL---LQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAK--L 2516
Query: 165 QQQREWKNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIES 224
+Q + + A+A+Q +E + Q++E ++ V + + + E
Sbjct: 2517 EQLFQDEVAKAQQLR------------EEQQRQQQQMEQERQRLVASMEEARRRQHEAEE 2564
Query: 225 VERKKQEK-------KQEQEDNLAEITNLLRGDL----------LSENPQQAASSFGPHR 267
R+KQE+ +++QE+ LAE LR L L+ + + AS +
Sbjct: 2565 GVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2624
Query: 268 VVP---DRWKGMTQEQLEQ------IRLVQKQQIQEKLRLQEEKRQR 305
+P D G E + R V Q++QE L E+ QR
Sbjct: 2625 TLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQR 2671
Score = 34.7 bits (78), Expect = 0.14
Identities = 45/213 (21%), Positives = 87/213 (40%), Gaps = 21/213 (9%)
Query: 149 HERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKA 208
H++ EE R + + AR + E L++ R+Q +E +K ++E+ R
Sbjct: 2200 HQKNLLDEELQR----LKAEATEAARQRSQVEEELFS-VRVQMEELSKLKARIEAENRAL 2254
Query: 209 VCASVKDFNKSQAIESVERKKQEKKQEQEDNL-------AEITNLLRGDLLSENPQQAAS 261
+ ++D + +Q E +K ++ E+ L A + L DL +
Sbjct: 2255 I---LRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKM 2311
Query: 262 SFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQRDLDWDRRRIQGARATL 321
+ V + + + +L Q QK+ QE+ R +E +++ QG + TL
Sbjct: 2312 LKEKMQAVQEATRLKAEAELLQ---QQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTL 2368
Query: 322 LFERQQWRRQRDLRRALDSSNLSLAKEQHLQKK 354
ERQ RQ ++ + L +A+ Q +
Sbjct: 2369 EAERQ---RQLEMSAEAERLKLRVAEMSRAQAR 2398
Score = 31.2 bits (69), Expect = 1.6
Identities = 38/174 (21%), Positives = 69/174 (39%), Gaps = 19/174 (10%)
Query: 185 TETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNLAEIT 244
T R++ +E Q+ E R A + + + A + K Q +++ +E
Sbjct: 1340 TLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQE 1399
Query: 245 NLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQ 304
++R + + + QQ S QE+L+Q+R + +IQ K R Q E +
Sbjct: 1400 EVVRREEAAVDAQQQKRSI--------------QEELQQLRQSSEAEIQAKAR-QAEAAE 1444
Query: 305 RDLDWDRRRIQGARATLLFERQQWRRQRDLRRALDSSNLSLAKEQHLQKKYMNE 358
R R RI+ + + + RQR + + A+E QK+ E
Sbjct: 1445 R----SRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE 1494
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 44.3 bits (103), Expect = 2e-04
Identities = 87/378 (23%), Positives = 157/378 (41%), Gaps = 60/378 (15%)
Query: 22 ELCRQKRVFNARNRII---GGDTEAWDVQVHDQKIKEATEKARHETFAAEMRQNDKIMCI 78
EL + K A NR + D +Q +K+K+ E+A + AA+ + ++ +
Sbjct: 2243 ELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQ--EAARLRQL 2300
Query: 79 LENRKKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKKDLPARQSDNDVRNTISGM 138
E + R + + + Q+ Q+ TR + + ++ L +K+L Q+ +
Sbjct: 2301 AEEDLAQQRALAEKMLKEKMQAVQEA-TRLKAE-AELLQQQKELAQEQARRLQEDKEQMA 2358
Query: 139 QKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTET----RLQFDET 194
Q+ E F + + ++ E S + +R K AE A+A E R Q +E
Sbjct: 2359 QQLAEETQGFQRTLEAERQRQLEMSAEAER-LKLRVAEMSRAQARAEEDAQRFRKQAEEI 2417
Query: 195 AKHLQKLE-STTRKAVCASVKDFNKSQ----------AIESVERKKQEKKQE-------- 235
+ L + E +T K + + Q AI +ER+K++ +QE
Sbjct: 2418 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2477
Query: 236 ------QEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQK 289
Q++ L + T L+ LSE S R + + EQL Q + +
Sbjct: 2478 EEMQTVQQEQLLQETQALQQSFLSEKD----SLLQRERFIEQEKAKL--EQLFQDEVAKA 2531
Query: 290 QQIQEKLRLQ----EEKRQR---DLDWDRRRIQGARATL------LFERQQWRRQRDLRR 336
QQ++E+ + Q E++RQR ++ RRR A + L + +Q RRQ++
Sbjct: 2532 QQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELL 2591
Query: 337 ALDS----SNLSLAKEQH 350
A ++ L L +EQH
Sbjct: 2592 AEENQRLREQLQLLEEQH 2609
Score = 38.9 bits (89), Expect = 0.008
Identities = 62/287 (21%), Positives = 127/287 (44%), Gaps = 51/287 (17%)
Query: 51 QKIKEATEKARHETFAAEMRQNDKIMCI--LENRKKR---DRKNLCRAINDFQQSFQKPE 105
Q+ ++ E+ + E+ +K+ + LE ++++ D + L AI + ++ +K +
Sbjct: 2408 QRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELER--EKEK 2465
Query: 106 TRREFDLSDPLALK-KDLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSL 164
++E L L LK +++ Q + ++ T + Q F+ E + +R++F E++ + L
Sbjct: 2466 LQQEAKL---LQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAK--L 2520
Query: 165 QQQREWKNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIES 224
+Q + + A+A+Q +E + Q++E ++ V + + + E
Sbjct: 2521 EQLFQDEVAKAQQLR------------EEQQRQQQQMEQERQRLVASMEEARRRQHEAEE 2568
Query: 225 VERKKQEK-------KQEQEDNLAEITNLLRGDL----------LSENPQQAASSFGPHR 267
R+KQE+ +++QE+ LAE LR L L+ + + AS +
Sbjct: 2569 GVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2628
Query: 268 VVP---DRWKGMTQEQLEQ------IRLVQKQQIQEKLRLQEEKRQR 305
+P D G E + R V Q++QE L E+ QR
Sbjct: 2629 TLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQR 2675
Score = 34.7 bits (78), Expect = 0.14
Identities = 45/213 (21%), Positives = 87/213 (40%), Gaps = 21/213 (9%)
Query: 149 HERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKA 208
H++ EE R + + AR + E L++ R+Q +E +K ++E+ R
Sbjct: 2204 HQKNLLDEELQR----LKAEATEAARQRSQVEEELFS-VRVQMEELSKLKARIEAENRAL 2258
Query: 209 VCASVKDFNKSQAIESVERKKQEKKQEQEDNL-------AEITNLLRGDLLSENPQQAAS 261
+ ++D + +Q E +K ++ E+ L A + L DL +
Sbjct: 2259 I---LRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKM 2315
Query: 262 SFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQRDLDWDRRRIQGARATL 321
+ V + + + +L Q QK+ QE+ R +E +++ QG + TL
Sbjct: 2316 LKEKMQAVQEATRLKAEAELLQ---QQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTL 2372
Query: 322 LFERQQWRRQRDLRRALDSSNLSLAKEQHLQKK 354
ERQ RQ ++ + L +A+ Q +
Sbjct: 2373 EAERQ---RQLEMSAEAERLKLRVAEMSRAQAR 2402
Score = 31.2 bits (69), Expect = 1.6
Identities = 38/174 (21%), Positives = 69/174 (39%), Gaps = 19/174 (10%)
Query: 185 TETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNLAEIT 244
T R++ +E Q+ E R A + + + A + K Q +++ +E
Sbjct: 1344 TLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQE 1403
Query: 245 NLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQ 304
++R + + + QQ S QE+L+Q+R + +IQ K R Q E +
Sbjct: 1404 EVVRREEAAVDAQQQKRSI--------------QEELQQLRQSSEAEIQAKAR-QAEAAE 1448
Query: 305 RDLDWDRRRIQGARATLLFERQQWRRQRDLRRALDSSNLSLAKEQHLQKKYMNE 358
R R RI+ + + + RQR + + A+E QK+ E
Sbjct: 1449 R----SRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE 1498
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 44.3 bits (103), Expect = 2e-04
Identities = 87/378 (23%), Positives = 157/378 (41%), Gaps = 60/378 (15%)
Query: 22 ELCRQKRVFNARNRII---GGDTEAWDVQVHDQKIKEATEKARHETFAAEMRQNDKIMCI 78
EL + K A NR + D +Q +K+K+ E+A + AA+ + ++ +
Sbjct: 2239 ELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQ--EAARLRQL 2296
Query: 79 LENRKKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKKDLPARQSDNDVRNTISGM 138
E + R + + + Q+ Q+ TR + + ++ L +K+L Q+ +
Sbjct: 2297 AEEDLAQQRALAEKMLKEKMQAVQEA-TRLKAE-AELLQQQKELAQEQARRLQEDKEQMA 2354
Query: 139 QKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTET----RLQFDET 194
Q+ E F + + ++ E S + +R K AE A+A E R Q +E
Sbjct: 2355 QQLAEETQGFQRTLEAERQRQLEMSAEAER-LKLRVAEMSRAQARAEEDAQRFRKQAEEI 2413
Query: 195 AKHLQKLE-STTRKAVCASVKDFNKSQ----------AIESVERKKQEKKQE-------- 235
+ L + E +T K + + Q AI +ER+K++ +QE
Sbjct: 2414 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2473
Query: 236 ------QEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQK 289
Q++ L + T L+ LSE S R + + EQL Q + +
Sbjct: 2474 EEMQTVQQEQLLQETQALQQSFLSEKD----SLLQRERFIEQEKAKL--EQLFQDEVAKA 2527
Query: 290 QQIQEKLRLQ----EEKRQR---DLDWDRRRIQGARATL------LFERQQWRRQRDLRR 336
QQ++E+ + Q E++RQR ++ RRR A + L + +Q RRQ++
Sbjct: 2528 QQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELL 2587
Query: 337 ALDS----SNLSLAKEQH 350
A ++ L L +EQH
Sbjct: 2588 AEENQRLREQLQLLEEQH 2605
Score = 38.9 bits (89), Expect = 0.008
Identities = 62/287 (21%), Positives = 127/287 (44%), Gaps = 51/287 (17%)
Query: 51 QKIKEATEKARHETFAAEMRQNDKIMCI--LENRKKR---DRKNLCRAINDFQQSFQKPE 105
Q+ ++ E+ + E+ +K+ + LE ++++ D + L AI + ++ +K +
Sbjct: 2404 QRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELER--EKEK 2461
Query: 106 TRREFDLSDPLALK-KDLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSL 164
++E L L LK +++ Q + ++ T + Q F+ E + +R++F E++ + L
Sbjct: 2462 LQQEAKL---LQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAK--L 2516
Query: 165 QQQREWKNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIES 224
+Q + + A+A+Q +E + Q++E ++ V + + + E
Sbjct: 2517 EQLFQDEVAKAQQLR------------EEQQRQQQQMEQERQRLVASMEEARRRQHEAEE 2564
Query: 225 VERKKQEK-------KQEQEDNLAEITNLLRGDL----------LSENPQQAASSFGPHR 267
R+KQE+ +++QE+ LAE LR L L+ + + AS +
Sbjct: 2565 GVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2624
Query: 268 VVP---DRWKGMTQEQLEQ------IRLVQKQQIQEKLRLQEEKRQR 305
+P D G E + R V Q++QE L E+ QR
Sbjct: 2625 TLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQR 2671
Score = 34.7 bits (78), Expect = 0.14
Identities = 45/213 (21%), Positives = 87/213 (40%), Gaps = 21/213 (9%)
Query: 149 HERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKA 208
H++ EE R + + AR + E L++ R+Q +E +K ++E+ R
Sbjct: 2200 HQKNLLDEELQR----LKAEATEAARQRSQVEEELFS-VRVQMEELSKLKARIEAENRAL 2254
Query: 209 VCASVKDFNKSQAIESVERKKQEKKQEQEDNL-------AEITNLLRGDLLSENPQQAAS 261
+ ++D + +Q E +K ++ E+ L A + L DL +
Sbjct: 2255 I---LRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKM 2311
Query: 262 SFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQRDLDWDRRRIQGARATL 321
+ V + + + +L Q QK+ QE+ R +E +++ QG + TL
Sbjct: 2312 LKEKMQAVQEATRLKAEAELLQ---QQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTL 2368
Query: 322 LFERQQWRRQRDLRRALDSSNLSLAKEQHLQKK 354
ERQ RQ ++ + L +A+ Q +
Sbjct: 2369 EAERQ---RQLEMSAEAERLKLRVAEMSRAQAR 2398
Score = 31.2 bits (69), Expect = 1.6
Identities = 38/174 (21%), Positives = 69/174 (39%), Gaps = 19/174 (10%)
Query: 185 TETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNLAEIT 244
T R++ +E Q+ E R A + + + A + K Q +++ +E
Sbjct: 1340 TLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQE 1399
Query: 245 NLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQ 304
++R + + + QQ S QE+L+Q+R + +IQ K R Q E +
Sbjct: 1400 EVVRREEAAVDAQQQKRSI--------------QEELQQLRQSSEAEIQAKAR-QAEAAE 1444
Query: 305 RDLDWDRRRIQGARATLLFERQQWRRQRDLRRALDSSNLSLAKEQHLQKKYMNE 358
R R RI+ + + + RQR + + A+E QK+ E
Sbjct: 1445 R----SRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE 1494
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 44.3 bits (103), Expect = 2e-04
Identities = 87/378 (23%), Positives = 157/378 (41%), Gaps = 60/378 (15%)
Query: 22 ELCRQKRVFNARNRII---GGDTEAWDVQVHDQKIKEATEKARHETFAAEMRQNDKIMCI 78
EL + K A NR + D +Q +K+K+ E+A + AA+ + ++ +
Sbjct: 2207 ELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQ--EAARLRQL 2264
Query: 79 LENRKKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKKDLPARQSDNDVRNTISGM 138
E + R + + + Q+ Q+ TR + + ++ L +K+L Q+ +
Sbjct: 2265 AEEDLAQQRALAEKMLKEKMQAVQEA-TRLKAE-AELLQQQKELAQEQARRLQEDKEQMA 2322
Query: 139 QKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTET----RLQFDET 194
Q+ E F + + ++ E S + +R K AE A+A E R Q +E
Sbjct: 2323 QQLAEETQGFQRTLEAERQRQLEMSAEAER-LKLRVAEMSRAQARAEEDAQRFRKQAEEI 2381
Query: 195 AKHLQKLE-STTRKAVCASVKDFNKSQ----------AIESVERKKQEKKQE-------- 235
+ L + E +T K + + Q AI +ER+K++ +QE
Sbjct: 2382 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2441
Query: 236 ------QEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQK 289
Q++ L + T L+ LSE S R + + EQL Q + +
Sbjct: 2442 EEMQTVQQEQLLQETQALQQSFLSEKD----SLLQRERFIEQEKAKL--EQLFQDEVAKA 2495
Query: 290 QQIQEKLRLQ----EEKRQR---DLDWDRRRIQGARATL------LFERQQWRRQRDLRR 336
QQ++E+ + Q E++RQR ++ RRR A + L + +Q RRQ++
Sbjct: 2496 QQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELL 2555
Query: 337 ALDS----SNLSLAKEQH 350
A ++ L L +EQH
Sbjct: 2556 AEENQRLREQLQLLEEQH 2573
Score = 38.9 bits (89), Expect = 0.008
Identities = 62/287 (21%), Positives = 127/287 (44%), Gaps = 51/287 (17%)
Query: 51 QKIKEATEKARHETFAAEMRQNDKIMCI--LENRKKR---DRKNLCRAINDFQQSFQKPE 105
Q+ ++ E+ + E+ +K+ + LE ++++ D + L AI + ++ +K +
Sbjct: 2372 QRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELER--EKEK 2429
Query: 106 TRREFDLSDPLALK-KDLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSL 164
++E L L LK +++ Q + ++ T + Q F+ E + +R++F E++ + L
Sbjct: 2430 LQQEAKL---LQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAK--L 2484
Query: 165 QQQREWKNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIES 224
+Q + + A+A+Q +E + Q++E ++ V + + + E
Sbjct: 2485 EQLFQDEVAKAQQLR------------EEQQRQQQQMEQERQRLVASMEEARRRQHEAEE 2532
Query: 225 VERKKQEK-------KQEQEDNLAEITNLLRGDL----------LSENPQQAASSFGPHR 267
R+KQE+ +++QE+ LAE LR L L+ + + AS +
Sbjct: 2533 GVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2592
Query: 268 VVP---DRWKGMTQEQLEQ------IRLVQKQQIQEKLRLQEEKRQR 305
+P D G E + R V Q++QE L E+ QR
Sbjct: 2593 TLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQR 2639
Score = 34.7 bits (78), Expect = 0.14
Identities = 45/213 (21%), Positives = 87/213 (40%), Gaps = 21/213 (9%)
Query: 149 HERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKA 208
H++ EE R + + AR + E L++ R+Q +E +K ++E+ R
Sbjct: 2168 HQKNLLDEELQR----LKAEATEAARQRSQVEEELFS-VRVQMEELSKLKARIEAENRAL 2222
Query: 209 VCASVKDFNKSQAIESVERKKQEKKQEQEDNL-------AEITNLLRGDLLSENPQQAAS 261
+ ++D + +Q E +K ++ E+ L A + L DL +
Sbjct: 2223 I---LRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKM 2279
Query: 262 SFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQRDLDWDRRRIQGARATL 321
+ V + + + +L Q QK+ QE+ R +E +++ QG + TL
Sbjct: 2280 LKEKMQAVQEATRLKAEAELLQ---QQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTL 2336
Query: 322 LFERQQWRRQRDLRRALDSSNLSLAKEQHLQKK 354
ERQ RQ ++ + L +A+ Q +
Sbjct: 2337 EAERQ---RQLEMSAEAERLKLRVAEMSRAQAR 2366
Score = 31.2 bits (69), Expect = 1.6
Identities = 38/174 (21%), Positives = 69/174 (39%), Gaps = 19/174 (10%)
Query: 185 TETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNLAEIT 244
T R++ +E Q+ E R A + + + A + K Q +++ +E
Sbjct: 1308 TLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQE 1367
Query: 245 NLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQ 304
++R + + + QQ S QE+L+Q+R + +IQ K R Q E +
Sbjct: 1368 EVVRREEAAVDAQQQKRSI--------------QEELQQLRQSSEAEIQAKAR-QAEAAE 1412
Query: 305 RDLDWDRRRIQGARATLLFERQQWRRQRDLRRALDSSNLSLAKEQHLQKKYMNE 358
R R RI+ + + + RQR + + A+E QK+ E
Sbjct: 1413 R----SRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE 1462
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.129 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,528,507
Number of Sequences: 37866
Number of extensions: 582580
Number of successful extensions: 5466
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 430
Number of HSP's that attempted gapping in prelim test: 3621
Number of HSP's gapped (non-prelim): 1364
length of query: 377
length of database: 18,247,518
effective HSP length: 104
effective length of query: 273
effective length of database: 14,309,454
effective search space: 3906480942
effective search space used: 3906480942
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.