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Search of human proteins with 240849353
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|240849353 gamma isoform of regulatory subunit B56, protein
phosphatase 2A isoform e [Homo sapiens]
(555 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|240849353 gamma isoform of regulatory subunit B56, protein ph... 1123 0.0
gi|31083259 gamma isoform of regulatory subunit B56, protein pho... 1002 0.0
gi|240849359 gamma isoform of regulatory subunit B56, protein ph... 954 0.0
gi|31083236 gamma isoform of regulatory subunit B56, protein pho... 906 0.0
gi|31083243 gamma isoform of regulatory subunit B56, protein pho... 838 0.0
gi|31083280 delta isoform of regulatory subunit B56, protein pho... 836 0.0
gi|5453954 delta isoform of regulatory subunit B56, protein phos... 833 0.0
gi|31083288 delta isoform of regulatory subunit B56, protein pho... 821 0.0
gi|5453950 protein phosphatase 2, regulatory subunit B (B56), al... 615 e-176
gi|5453956 epsilon isoform of regulatory subunit B56, protein ph... 613 e-176
gi|5453952 beta isoform of regulatory subunit B56, protein phosp... 590 e-169
gi|4505727 peroxisomal biogenesis factor 3 [Homo sapiens] 34 0.40
gi|42518068 trans-golgi network protein 2 [Homo sapiens] 33 0.68
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 33 0.89
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 33 0.89
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 32 1.2
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 32 1.2
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 32 1.2
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 32 1.2
gi|67089157 promyelocytic leukemia protein isoform 2 [Homo sapiens] 32 1.2
gi|15451765 promyelocytic leukemia protein isoform 9 [Homo sapiens] 32 1.2
gi|4505903 promyelocytic leukemia protein isoform 6 [Homo sapiens] 32 1.2
gi|67089149 promyelocytic leukemia protein isoform 1 [Homo sapiens] 32 1.2
gi|109637788 promyelocytic leukemia protein isoform 5 [Homo sapi... 32 1.2
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa... 32 1.5
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] 32 2.0
gi|222080092 WD repeat domain 91 [Homo sapiens] 31 2.6
gi|4505183 CD99 antigen isoform a precursor [Homo sapiens] 31 2.6
gi|112734867 retinitis pigmentosa GTPase regulator interacting p... 31 2.6
gi|148839376 PWWP domain containing 2 isoform 1 [Homo sapiens] 31 2.6
>gi|240849353 gamma isoform of regulatory subunit B56, protein
phosphatase 2A isoform e [Homo sapiens]
Length = 555
Score = 1123 bits (2905), Expect = 0.0
Identities = 555/555 (100%), Positives = 555/555 (100%)
Query: 1 MPNKNKKEKESPKAGKSGKSSKEGQDTVESEGTSPEEPSSPKVPPPLLPELLVLIFGGLQ 60
MPNKNKKEKESPKAGKSGKSSKEGQDTVESEGTSPEEPSSPKVPPPLLPELLVLIFGGLQ
Sbjct: 1 MPNKNKKEKESPKAGKSGKSSKEGQDTVESEGTSPEEPSSPKVPPPLLPELLVLIFGGLQ 60
Query: 61 GRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITE 120
GRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITE
Sbjct: 61 GRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITE 120
Query: 121 PIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPD 180
PIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPD
Sbjct: 121 PIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPD 180
Query: 181 FQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFY 240
FQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFY
Sbjct: 181 FQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFY 240
Query: 241 RFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAY 300
RFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAY
Sbjct: 241 RFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAY 300
Query: 301 CVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFR 360
CVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFR
Sbjct: 301 CVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFR 360
Query: 361 QLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGL 420
QLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGL
Sbjct: 361 QLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGL 420
Query: 421 IYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYTVYSQA 480
IYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYTVYSQA
Sbjct: 421 IYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYTVYSQA 480
Query: 481 STMSIPVAMETDGPLFEDVQMLRKTVKDEAHQAQKDPKKDRPLARRKSELPQDPHTKKAL 540
STMSIPVAMETDGPLFEDVQMLRKTVKDEAHQAQKDPKKDRPLARRKSELPQDPHTKKAL
Sbjct: 481 STMSIPVAMETDGPLFEDVQMLRKTVKDEAHQAQKDPKKDRPLARRKSELPQDPHTKKAL 540
Query: 541 EAHCRADELASQDGR 555
EAHCRADELASQDGR
Sbjct: 541 EAHCRADELASQDGR 555
>gi|31083259 gamma isoform of regulatory subunit B56, protein
phosphatase 2A isoform a [Homo sapiens]
Length = 524
Score = 1002 bits (2590), Expect = 0.0
Identities = 494/494 (100%), Positives = 494/494 (100%)
Query: 62 RDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEP 121
RDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEP
Sbjct: 31 RDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEP 90
Query: 122 IYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDF 181
IYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDF
Sbjct: 91 IYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDF 150
Query: 182 QPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYR 241
QPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYR
Sbjct: 151 QPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYR 210
Query: 242 FIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYC 301
FIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYC
Sbjct: 211 FIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYC 270
Query: 302 VVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQ 361
VVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQ
Sbjct: 271 VVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQ 330
Query: 362 LAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLI 421
LAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLI
Sbjct: 331 LAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLI 390
Query: 422 YNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYTVYSQAS 481
YNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYTVYSQAS
Sbjct: 391 YNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYTVYSQAS 450
Query: 482 TMSIPVAMETDGPLFEDVQMLRKTVKDEAHQAQKDPKKDRPLARRKSELPQDPHTKKALE 541
TMSIPVAMETDGPLFEDVQMLRKTVKDEAHQAQKDPKKDRPLARRKSELPQDPHTKKALE
Sbjct: 451 TMSIPVAMETDGPLFEDVQMLRKTVKDEAHQAQKDPKKDRPLARRKSELPQDPHTKKALE 510
Query: 542 AHCRADELASQDGR 555
AHCRADELASQDGR
Sbjct: 511 AHCRADELASQDGR 524
>gi|240849359 gamma isoform of regulatory subunit B56, protein
phosphatase 2A isoform f [Homo sapiens]
Length = 540
Score = 954 bits (2467), Expect = 0.0
Identities = 492/579 (84%), Positives = 497/579 (85%), Gaps = 63/579 (10%)
Query: 1 MPNKNKKEKESPKAGKSGKSSKEGQDTVESEGTSPEEPSSPKVPPPLLPELLVLI----- 55
MPNKNKKEKESPKAGKSGKSSKEGQDTVESE S + S VP + ++ V +
Sbjct: 1 MPNKNKKEKESPKAGKSGKSSKEGQDTVESEQISVRKNSLVAVPSTVSAKIKVPVSQPIV 60
Query: 56 ----------FGGLQGR---------DVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKW 96
F R DVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKW
Sbjct: 61 KKDKRQNSSRFSASNNRELQKLPSLKDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKW 120
Query: 97 KEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEP 156
KEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEP
Sbjct: 121 KEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEP 180
Query: 157 TLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTT 216
TLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTT
Sbjct: 181 TLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTT 240
Query: 217 LHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKI 276
LHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKI
Sbjct: 241 LHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKI 300
Query: 277 FLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFL 336
FLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFL
Sbjct: 301 FLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFL 360
Query: 337 NELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAK 396
NELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAK
Sbjct: 361 NELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAK 420
Query: 397 ILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKE 456
ILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKE
Sbjct: 421 ILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKE 480
Query: 457 REEAWVKIENLAKANPQYTVYSQASTMSIPVAMETDGPLFEDVQMLRKTVKDEAHQAQKD 516
REEAWVKIENLAKANP QAQKD
Sbjct: 481 REEAWVKIENLAKANP---------------------------------------QAQKD 501
Query: 517 PKKDRPLARRKSELPQDPHTKKALEAHCRADELASQDGR 555
PKKDRPLARRKSELPQDPHTKKALEAHCRADELASQDGR
Sbjct: 502 PKKDRPLARRKSELPQDPHTKKALEAHCRADELASQDGR 540
>gi|31083236 gamma isoform of regulatory subunit B56, protein
phosphatase 2A isoform b [Homo sapiens]
Length = 485
Score = 906 bits (2342), Expect = 0.0
Identities = 455/494 (92%), Positives = 455/494 (92%), Gaps = 39/494 (7%)
Query: 62 RDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEP 121
RDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEP
Sbjct: 31 RDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEP 90
Query: 122 IYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDF 181
IYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDF
Sbjct: 91 IYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDF 150
Query: 182 QPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYR 241
QPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYR
Sbjct: 151 QPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYR 210
Query: 242 FIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYC 301
FIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYC
Sbjct: 211 FIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYC 270
Query: 302 VVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQ 361
VVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQ
Sbjct: 271 VVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQ 330
Query: 362 LAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLI 421
LAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLI
Sbjct: 331 LAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLI 390
Query: 422 YNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYTVYSQAS 481
YNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANP
Sbjct: 391 YNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANP--------- 441
Query: 482 TMSIPVAMETDGPLFEDVQMLRKTVKDEAHQAQKDPKKDRPLARRKSELPQDPHTKKALE 541
QAQKDPKKDRPLARRKSELPQDPHTKKALE
Sbjct: 442 ------------------------------QAQKDPKKDRPLARRKSELPQDPHTKKALE 471
Query: 542 AHCRADELASQDGR 555
AHCRADELASQDGR
Sbjct: 472 AHCRADELASQDGR 485
>gi|31083243 gamma isoform of regulatory subunit B56, protein
phosphatase 2A isoform c [Homo sapiens]
Length = 449
Score = 838 bits (2165), Expect = 0.0
Identities = 412/412 (100%), Positives = 412/412 (100%)
Query: 62 RDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEP 121
RDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEP
Sbjct: 31 RDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEP 90
Query: 122 IYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDF 181
IYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDF
Sbjct: 91 IYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDF 150
Query: 182 QPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYR 241
QPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYR
Sbjct: 151 QPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYR 210
Query: 242 FIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYC 301
FIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYC
Sbjct: 211 FIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYC 270
Query: 302 VVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQ 361
VVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQ
Sbjct: 271 VVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQ 330
Query: 362 LAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLI 421
LAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLI
Sbjct: 331 LAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLI 390
Query: 422 YNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQ 473
YNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQ
Sbjct: 391 YNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQ 442
>gi|31083280 delta isoform of regulatory subunit B56, protein
phosphatase 2A isoform 2 [Homo sapiens]
Length = 570
Score = 836 bits (2159), Expect = 0.0
Identities = 425/575 (73%), Positives = 478/575 (83%), Gaps = 29/575 (5%)
Query: 1 MPNKNKKEKESPKAGK-SGKSSKEGQD-------------------TVESEGTSPEEPSS 40
MP K KKEKE PK K + K S G+D +S+ S + S
Sbjct: 1 MPYKLKKEKEPPKVAKCTAKPSSSGKDGGGENTEEAQPQPQPQPQPQAQSQPPSSNKRPS 60
Query: 41 PKVPPPLLPELLVLIFGGLQGRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVK 100
PPP +L + + G P +++LFIQKLRQCCVLFDFVSDPLSDLK+KEVK
Sbjct: 61 NSTPPPT--QLSKIKYSG-----GPQIVKKELFIQKLRQCCVLFDFVSDPLSDLKFKEVK 113
Query: 101 RAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEA 160
RA L+EMVEYITH+R+V+TE IYPE V MF+VN+FRTLPPSSNPTGAEFDPEEDEPTLEA
Sbjct: 114 RAGLNEMVEYITHSRDVVTEAIYPEAVTMFSVNLFRTLPPSSNPTGAEFDPEEDEPTLEA 173
Query: 161 AWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRI 220
AWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVL LL+LFDSEDPRERDFLKT LHRI
Sbjct: 174 AWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLALLDLFDSEDPRERDFLKTILHRI 233
Query: 221 YGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLK 280
YGKFLGLRAYIR+QIN+IFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHK+FL++
Sbjct: 234 YGKFLGLRAYIRRQINHIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKMFLIR 293
Query: 281 VLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELE 340
VLLPLHKVKSLSVYHPQLAYCVVQFLEK+S+LTEPV++ LLK+WPKTHSPKEVMFLNELE
Sbjct: 294 VLLPLHKVKSLSVYHPQLAYCVVQFLEKESSLTEPVIVGLLKFWPKTHSPKEVMFLNELE 353
Query: 341 EILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPI 400
EILDVIEPSEF K+MEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAA++LPI
Sbjct: 354 EILDVIEPSEFSKVMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAARVLPI 413
Query: 401 MFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEA 460
MFP+LYRNSK+HWNKTIHGLIYNALKLFMEMNQKLFDDCTQQ+KAEK K + +MKEREE
Sbjct: 414 MFPALYRNSKSHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQYKAEKQKGRFRMKEREEM 473
Query: 461 WVKIENLAKANPQYTVYSQASTMSIPVAMETDGPLFEDVQMLRKTVKDEAHQAQKDPKKD 520
W KIE LA+ NPQY ++ + +MET+ P ED+Q+L++TV+ EA Q KD KK+
Sbjct: 474 WQKIEELARLNPQYPMFRAPPPLPPVYSMETETPTAEDIQLLKRTVETEAVQMLKDIKKE 533
Query: 521 RPLARRKSELPQDPHTKKALEAHCRADEL--ASQD 553
+ L RRKSELPQD +T KALEAH RA+E ASQ+
Sbjct: 534 KVLLRRKSELPQDVYTIKALEAHKRAEEFLTASQE 568
>gi|5453954 delta isoform of regulatory subunit B56, protein
phosphatase 2A isoform 1 [Homo sapiens]
Length = 602
Score = 833 bits (2152), Expect = 0.0
Identities = 431/600 (71%), Positives = 483/600 (80%), Gaps = 47/600 (7%)
Query: 1 MPNKNKKEKESPKAGK-SGKSSKEGQD-----TVESEG---------TSPEEPSSPKVP- 44
MP K KKEKE PK K + K S G+D T E++ + PSS K P
Sbjct: 1 MPYKLKKEKEPPKVAKCTAKPSSSGKDGGGENTEEAQPQPQPQPQPQAQSQPPSSNKRPS 60
Query: 45 ---PPLLPELLVLIFGGLQG--------------------------RDVPPADQEKLFIQ 75
PP + GG Q +D P ++E+LFIQ
Sbjct: 61 NSTPPPTQLSKIKYSGGPQIVKKERRQSSSRFNLSKNRELQKLPALKDSPTQEREELFIQ 120
Query: 76 KLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMF 135
KLRQCCVLFDFVSDPLSDLK+KEVKRA L+EMVEYITH+R+V+TE IYPE V MF+VN+F
Sbjct: 121 KLRQCCVLFDFVSDPLSDLKFKEVKRAGLNEMVEYITHSRDVVTEAIYPEAVTMFSVNLF 180
Query: 136 RTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFV 195
RTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFV
Sbjct: 181 RTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFV 240
Query: 196 LQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAEL 255
L LL+LFDSEDPRERDFLKT LHRIYGKFLGLRAYIR+QIN+IFYRFIYETEHHNGIAEL
Sbjct: 241 LALLDLFDSEDPRERDFLKTILHRIYGKFLGLRAYIRRQINHIFYRFIYETEHHNGIAEL 300
Query: 256 LEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEP 315
LEILGSIINGFALPLKEEHK+FL++VLLPLHKVKSLSVYHPQLAYCVVQFLEK+S+LTEP
Sbjct: 301 LEILGSIINGFALPLKEEHKMFLIRVLLPLHKVKSLSVYHPQLAYCVVQFLEKESSLTEP 360
Query: 316 VVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAE 375
V++ LLK+WPKTHSPKEVMFLNELEEILDVIEPSEF K+MEPLFRQLAKCVSSPHFQVAE
Sbjct: 361 VIVGLLKFWPKTHSPKEVMFLNELEEILDVIEPSEFSKVMEPLFRQLAKCVSSPHFQVAE 420
Query: 376 RALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKL 435
RALYYWNNEYIMSLISDNAA++LPIMFP+LYRNSK+HWNKTIHGLIYNALKLFMEMNQKL
Sbjct: 421 RALYYWNNEYIMSLISDNAARVLPIMFPALYRNSKSHWNKTIHGLIYNALKLFMEMNQKL 480
Query: 436 FDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYTVYSQASTMSIPVAMETDGPL 495
FDDCTQQ+KAEK K + +MKEREE W KIE LA+ NPQY ++ + +MET+ P
Sbjct: 481 FDDCTQQYKAEKQKGRFRMKEREEMWQKIEELARLNPQYPMFRAPPPLPPVYSMETETPT 540
Query: 496 FEDVQMLRKTVKDEAHQAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADEL--ASQD 553
ED+Q+L++TV+ EA Q KD KK++ L RRKSELPQD +T KALEAH RA+E ASQ+
Sbjct: 541 AEDIQLLKRTVETEAVQMLKDIKKEKVLLRRKSELPQDVYTIKALEAHKRAEEFLTASQE 600
>gi|31083288 delta isoform of regulatory subunit B56, protein
phosphatase 2A isoform 3 [Homo sapiens]
Length = 496
Score = 821 bits (2120), Expect = 0.0
Identities = 401/487 (82%), Positives = 446/487 (91%), Gaps = 2/487 (0%)
Query: 69 QEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVH 128
+++LFIQKLRQCCVLFDFVSDPLSDLK+KEVKRA L+EMVEYITH+R+V+TE IYPE V
Sbjct: 8 EKELFIQKLRQCCVLFDFVSDPLSDLKFKEVKRAGLNEMVEYITHSRDVVTEAIYPEAVT 67
Query: 129 MFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKK 188
MF+VN+FRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKK
Sbjct: 68 MFSVNLFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKK 127
Query: 189 YIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEH 248
YIDQKFVL LL+LFDSEDPRERDFLKT LHRIYGKFLGLRAYIR+QIN+IFYRFIYETEH
Sbjct: 128 YIDQKFVLALLDLFDSEDPRERDFLKTILHRIYGKFLGLRAYIRRQINHIFYRFIYETEH 187
Query: 249 HNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEK 308
HNGIAELLEILGSIINGFALPLKEEHK+FL++VLLPLHKVKSLSVYHPQLAYCVVQFLEK
Sbjct: 188 HNGIAELLEILGSIINGFALPLKEEHKMFLIRVLLPLHKVKSLSVYHPQLAYCVVQFLEK 247
Query: 309 DSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSS 368
+S+LTEPV++ LLK+WPKTHSPKEVMFLNELEEILDVIEPSEF K+MEPLFRQLAKCVSS
Sbjct: 248 ESSLTEPVIVGLLKFWPKTHSPKEVMFLNELEEILDVIEPSEFSKVMEPLFRQLAKCVSS 307
Query: 369 PHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLF 428
PHFQVAERALYYWNNEYIMSLISDNAA++LPIMFP+LYRNSK+HWNKTIHGLIYNALKLF
Sbjct: 308 PHFQVAERALYYWNNEYIMSLISDNAARVLPIMFPALYRNSKSHWNKTIHGLIYNALKLF 367
Query: 429 MEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYTVYSQASTMSIPVA 488
MEMNQKLFDDCTQQ+KAEK K + +MKEREE W KIE LA+ NPQY ++ + +
Sbjct: 368 MEMNQKLFDDCTQQYKAEKQKGRFRMKEREEMWQKIEELARLNPQYPMFRAPPPLPPVYS 427
Query: 489 METDGPLFEDVQMLRKTVKDEAHQAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADE 548
MET+ P ED+Q+L++TV+ EA Q KD KK++ L RRKSELPQD +T KALEAH RA+E
Sbjct: 428 METETPTAEDIQLLKRTVETEAVQMLKDIKKEKVLLRRKSELPQDVYTIKALEAHKRAEE 487
Query: 549 L--ASQD 553
ASQ+
Sbjct: 488 FLTASQE 494
>gi|5453950 protein phosphatase 2, regulatory subunit B (B56), alpha
isoform [Homo sapiens]
Length = 486
Score = 615 bits (1585), Expect = e-176
Identities = 311/476 (65%), Positives = 368/476 (77%), Gaps = 20/476 (4%)
Query: 15 GKSGKSSKEGQDTVESEGTSPEEPSSPKVPPPLLPELLVLIFGGLQGRDVPPADQEKLFI 74
G + KS ++ Q S+G+S + LP+L +D +Q++LF
Sbjct: 23 GFTRKSVRKAQRQKRSQGSSQFRSQGSQAELHPLPQL----------KDATSNEQQELFC 72
Query: 75 QKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNM 134
QKL+QCC+LFDF+ D +SDLK KE+KRA L+E+VEY++ NR VI E Y ++V M + N+
Sbjct: 73 QKLQQCCILFDFM-DSVSDLKSKEIKRATLNELVEYVSTNRGVIVESAYSDIVKMISANI 131
Query: 135 FRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKF 194
FRTLPPS NP +FDPEEDEPTLEA+WPH+QLVYEFFLRFLESPDFQP+IAK+YIDQKF
Sbjct: 132 FRTLPPSDNP---DFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIAKRYIDQKF 188
Query: 195 VLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAE 254
V QLLELFDSEDPRERDFLKT LHRIYGKFLGLRA+IRKQINNIF RFIYETEH NG+AE
Sbjct: 189 VQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEHFNGVAE 248
Query: 255 LLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTE 314
LLEILGSIINGFALPLK EHK FL+KVL+P+H K L+++H QLAYCVVQFLEKD+TLTE
Sbjct: 249 LLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFLEKDTTLTE 308
Query: 315 PVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVA 374
PV+ LLK+WPKT S KEVMFL E+EEILDVIEP++F KI EPLF+Q++KCVSS HFQVA
Sbjct: 309 PVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCVSSSHFQVA 368
Query: 375 ERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQK 434
ERALY+WNNEYI+SLI +N KILPIMF SLY+ SK HWN TI L+YN LK MEMN K
Sbjct: 369 ERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLKTLMEMNGK 428
Query: 435 LFDDCTQQFKAEKLKEKLKMKEREEAWVKIEN------LAKANPQYTVYSQASTMS 484
LFDD T +KAE+ +EK K EREE W K+E L K N Y ++S S S
Sbjct: 429 LFDDLTSSYKAERQREKKKELEREELWKKLEELKLKKALEKQNSAYNMHSILSNTS 484
>gi|5453956 epsilon isoform of regulatory subunit B56, protein
phosphatase 2A [Homo sapiens]
Length = 467
Score = 613 bits (1582), Expect = e-176
Identities = 298/406 (73%), Positives = 349/406 (85%), Gaps = 4/406 (0%)
Query: 62 RDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEP 121
+DVP ++Q +LF++KL+QCCV+FDF+ D LSDLK KE KR+ L+E+V+YIT +R +TE
Sbjct: 52 KDVPSSEQPELFLKKLQQCCVIFDFM-DTLSDLKMKEYKRSTLNELVDYITISRGCLTEQ 110
Query: 122 IYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDF 181
YPEVV M + N+FRTLPPS + EFDPEEDEPTLEA+WPHLQLVYEFF+RFLES +F
Sbjct: 111 TYPEVVRMVSCNIFRTLPPSDSN---EFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEF 167
Query: 182 QPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYR 241
QP+IAKKYIDQKFVLQLLELFDSEDPRERD+LKT LHRIYGKFLGLRA+IRKQINNIF R
Sbjct: 168 QPSIAKKYIDQKFVLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFLR 227
Query: 242 FIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYC 301
F+YETEH NG+AELLEILGSIINGFALPLK EHK FL+KVL+PLH V+SLS++H QLAYC
Sbjct: 228 FVYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYC 287
Query: 302 VVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQ 361
+VQFLEKD +LTEPV+ L+K+WPKT S KEVMFL ELEEILDVIEPS+FVKI EPLF+Q
Sbjct: 288 IVQFLEKDPSLTEPVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQ 347
Query: 362 LAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLI 421
+AKCVSSPHFQVAERALYYWNNEYIMSLI +N+ ILPIMF SLYR SK HWN I L+
Sbjct: 348 IAKCVSSPHFQVAERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWNPAIVALV 407
Query: 422 YNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENL 467
YN LK FMEMN +FD+ T +K+++ +EK K KEREE W K+E+L
Sbjct: 408 YNVLKAFMEMNSTMFDELTATYKSDRQREKKKEKEREELWKKLEDL 453
>gi|5453952 beta isoform of regulatory subunit B56, protein
phosphatase 2A [Homo sapiens]
Length = 497
Score = 590 bits (1522), Expect = e-169
Identities = 286/406 (70%), Positives = 341/406 (83%), Gaps = 4/406 (0%)
Query: 62 RDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEP 121
+DVP ++ +L +KL QC V+FDF+ D ++DLK KEVKRAAL+E+VE + R V+ EP
Sbjct: 66 KDVPASELHELLSRKLAQCGVMFDFL-DCVADLKGKEVKRAALNELVECVGSTRGVLIEP 124
Query: 122 IYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDF 181
+YP+++ M +VN+FRTLPPS NP EFDPEEDEP LE +WPHLQLVYEFFLRFLESPDF
Sbjct: 125 VYPDIIRMISVNIFRTLPPSENP---EFDPEEDEPNLEPSWPHLQLVYEFFLRFLESPDF 181
Query: 182 QPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYR 241
QP++AK+Y+DQKFVL LLELFDSEDPRER++LKT LHR+YGKFLGLRAYIRKQ N+IF R
Sbjct: 182 QPSVAKRYVDQKFVLMLLELFDSEDPREREYLKTILHRVYGKFLGLRAYIRKQCNHIFLR 241
Query: 242 FIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYC 301
FIYE EH NG+AELLEILGSIINGFALPLK EHK FL++VL+PLH VKSLSV+H QLAYC
Sbjct: 242 FIYEFEHFNGVAELLEILGSIINGFALPLKTEHKQFLVRVLIPLHSVKSLSVFHAQLAYC 301
Query: 302 VVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQ 361
VVQFLEKD+TLTE V+ LLKYWPKT + KEVMFL E+EEILDVIEPS+FVKI EPLF+Q
Sbjct: 302 VVQFLEKDATLTEHVIRGLLKYWPKTCTQKEVMFLGEMEEILDVIEPSQFVKIQEPLFKQ 361
Query: 362 LAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLI 421
+A+CVSSPHFQVAERALY+WNNEYI+SLI DN +LP +F +LY+ SK HWN+TI LI
Sbjct: 362 VARCVSSPHFQVAERALYFWNNEYILSLIEDNCHTVLPAVFGTLYQVSKEHWNQTIVSLI 421
Query: 422 YNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENL 467
YN LK FMEMN KLFD+ T +K EK +E+ K +ER+E W +E L
Sbjct: 422 YNVLKTFMEMNGKLFDELTASYKLEKQQEQQKAQERQELWQGLEEL 467
>gi|4505727 peroxisomal biogenesis factor 3 [Homo sapiens]
Length = 373
Score = 33.9 bits (76), Expect = 0.40
Identities = 33/163 (20%), Positives = 77/163 (47%), Gaps = 18/163 (11%)
Query: 250 NGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKD 309
+G+ EL+ ++ + + +H + LL + L ++++L H ++ + KD
Sbjct: 174 DGLTELITVIKQAVQKVLGSVSLKHSLSLLDLEQKLKEIRNLVEQHKSSSW-----INKD 228
Query: 310 STLTEPVVMALLKYWPKTH--------SPKEVMFLNELEEILDVIEPSEFVKIMEP-LFR 360
+ +P++ + +T SP+++ + L E D++E +F ++ L R
Sbjct: 229 GS--KPLLCHYMMPDEETPLAVQACGLSPRDITTIKLLNETRDMLESPDFSTVLNTCLNR 286
Query: 361 QLAKCVSS--PHFQVAERALYYWNNEYIMSLISDNAAKILPIM 401
++ + + F+ E+ L + N+ +S +S AKI+PI+
Sbjct: 287 GFSRLLDNMAEFFRPTEQDLQHGNSMNSLSSVSLPLAKIIPIV 329
>gi|42518068 trans-golgi network protein 2 [Homo sapiens]
Length = 437
Score = 33.1 bits (74), Expect = 0.68
Identities = 20/51 (39%), Positives = 29/51 (56%), Gaps = 2/51 (3%)
Query: 1 MPNKNKKEKESPKAGKSGKSSKEGQDTVESEGTS-PEEPSSPKVPPPLLPE 50
+PNK+ EK++PK G S KS E Q ++ S EE +S P ++PE
Sbjct: 206 VPNKSGAEKQTPKDG-SNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPE 255
>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 2 [Homo sapiens]
Length = 1403
Score = 32.7 bits (73), Expect = 0.89
Identities = 71/291 (24%), Positives = 118/291 (40%), Gaps = 51/291 (17%)
Query: 266 FALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWP 325
F P K E +I LK + K K LS + + S T M +Y P
Sbjct: 790 FVPPEKHEKEIIALKSNIVELK-KQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYVP 848
Query: 326 -KTHSPKEVMFLNEL----EEILDVIEP-----SEFVKIM---EPLFRQLAKC---VSSP 369
KTH ++ + L E+LDV + EFVKI E L R L + +
Sbjct: 849 VKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAE 908
Query: 370 HFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFM 429
+ +AE + M + D+ A+IL + YR + T+H I A K +
Sbjct: 909 YISLAEHEAKMSSLSQSMRKVQDSNAEIL-----ANYRKGQEEI-VTLHAEI-KAQKKEL 961
Query: 430 EMNQKL----------FDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYTVYSQ 479
+ Q+ F++C ++FKA + + K ++ E+ + + E K N Q
Sbjct: 962 DTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQ------ 1015
Query: 480 ASTMSIPVAMETDGPLFEDVQMLRKTVKDEAHQAQKDPKKDRPLARRKSEL 530
E D L +++ L+K ++D+ +K + +R L+R+ EL
Sbjct: 1016 ----------END-KLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDEL 1055
>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 1 [Homo sapiens]
Length = 1416
Score = 32.7 bits (73), Expect = 0.89
Identities = 71/291 (24%), Positives = 118/291 (40%), Gaps = 51/291 (17%)
Query: 266 FALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWP 325
F P K E +I LK + K K LS + + S T M +Y P
Sbjct: 803 FVPPEKHEKEIIALKSNIVELK-KQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYVP 861
Query: 326 -KTHSPKEVMFLNEL----EEILDVIEP-----SEFVKIM---EPLFRQLAKC---VSSP 369
KTH ++ + L E+LDV + EFVKI E L R L + +
Sbjct: 862 VKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAE 921
Query: 370 HFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFM 429
+ +AE + M + D+ A+IL + YR + T+H I A K +
Sbjct: 922 YISLAEHEAKMSSLSQSMRKVQDSNAEIL-----ANYRKGQEEI-VTLHAEI-KAQKKEL 974
Query: 430 EMNQKL----------FDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYTVYSQ 479
+ Q+ F++C ++FKA + + K ++ E+ + + E K N Q
Sbjct: 975 DTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQ------ 1028
Query: 480 ASTMSIPVAMETDGPLFEDVQMLRKTVKDEAHQAQKDPKKDRPLARRKSEL 530
E D L +++ L+K ++D+ +K + +R L+R+ EL
Sbjct: 1029 ----------END-KLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDEL 1068
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 32.3 bits (72), Expect = 1.2
Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 4/62 (6%)
Query: 473 QYTVYSQASTMSIPVAMETDGPLFEDVQMLRKT----VKDEAHQAQKDPKKDRPLARRKS 528
Q TV+ S +P+ T GP E +Q L K ++ E +A+ K++ +R+
Sbjct: 694 QPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQE 753
Query: 529 EL 530
EL
Sbjct: 754 EL 755
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 32.3 bits (72), Expect = 1.2
Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 4/62 (6%)
Query: 473 QYTVYSQASTMSIPVAMETDGPLFEDVQMLRKT----VKDEAHQAQKDPKKDRPLARRKS 528
Q TV+ S +P+ T GP E +Q L K ++ E +A+ K++ +R+
Sbjct: 721 QPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQE 780
Query: 529 EL 530
EL
Sbjct: 781 EL 782
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 32.3 bits (72), Expect = 1.2
Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 4/62 (6%)
Query: 473 QYTVYSQASTMSIPVAMETDGPLFEDVQMLRKT----VKDEAHQAQKDPKKDRPLARRKS 528
Q TV+ S +P+ T GP E +Q L K ++ E +A+ K++ +R+
Sbjct: 700 QPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQE 759
Query: 529 EL 530
EL
Sbjct: 760 EL 761
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 32.3 bits (72), Expect = 1.2
Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 4/62 (6%)
Query: 473 QYTVYSQASTMSIPVAMETDGPLFEDVQMLRKT----VKDEAHQAQKDPKKDRPLARRKS 528
Q TV+ S +P+ T GP E +Q L K ++ E +A+ K++ +R+
Sbjct: 700 QPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQE 759
Query: 529 EL 530
EL
Sbjct: 760 EL 761
>gi|67089157 promyelocytic leukemia protein isoform 2 [Homo sapiens]
Length = 611
Score = 32.3 bits (72), Expect = 1.2
Identities = 31/96 (32%), Positives = 41/96 (42%), Gaps = 12/96 (12%)
Query: 456 EREEAWVKIENLAKANPQYTVYSQASTMSIPV-AMETDGPLF-EDVQMLRKTVKDEAHQA 513
ER +A V+ LA+A P V S +PV A GP + EDV K + Q
Sbjct: 423 ERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQT 482
Query: 514 Q---------KDPKKDRPLARRKSELPQDPHTKKAL 540
Q + K+ LAR E P+ P T KA+
Sbjct: 483 QCPRKVIKMESEEGKEARLARSSPEQPR-PSTSKAV 517
>gi|15451765 promyelocytic leukemia protein isoform 9 [Homo sapiens]
Length = 829
Score = 32.3 bits (72), Expect = 1.2
Identities = 31/96 (32%), Positives = 41/96 (42%), Gaps = 12/96 (12%)
Query: 456 EREEAWVKIENLAKANPQYTVYSQASTMSIPV-AMETDGPLF-EDVQMLRKTVKDEAHQA 513
ER +A V+ LA+A P V S +PV A GP + EDV K + Q
Sbjct: 423 ERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQT 482
Query: 514 Q---------KDPKKDRPLARRKSELPQDPHTKKAL 540
Q + K+ LAR E P+ P T KA+
Sbjct: 483 QCPRKVIKMESEEGKEARLARSSPEQPR-PSTSKAV 517
>gi|4505903 promyelocytic leukemia protein isoform 6 [Homo sapiens]
Length = 633
Score = 32.3 bits (72), Expect = 1.2
Identities = 31/96 (32%), Positives = 41/96 (42%), Gaps = 12/96 (12%)
Query: 456 EREEAWVKIENLAKANPQYTVYSQASTMSIPV-AMETDGPLF-EDVQMLRKTVKDEAHQA 513
ER +A V+ LA+A P V S +PV A GP + EDV K + Q
Sbjct: 423 ERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQT 482
Query: 514 Q---------KDPKKDRPLARRKSELPQDPHTKKAL 540
Q + K+ LAR E P+ P T KA+
Sbjct: 483 QCPRKVIKMESEEGKEARLARSSPEQPR-PSTSKAV 517
>gi|67089149 promyelocytic leukemia protein isoform 1 [Homo sapiens]
Length = 882
Score = 32.3 bits (72), Expect = 1.2
Identities = 31/96 (32%), Positives = 41/96 (42%), Gaps = 12/96 (12%)
Query: 456 EREEAWVKIENLAKANPQYTVYSQASTMSIPV-AMETDGPLF-EDVQMLRKTVKDEAHQA 513
ER +A V+ LA+A P V S +PV A GP + EDV K + Q
Sbjct: 423 ERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQT 482
Query: 514 Q---------KDPKKDRPLARRKSELPQDPHTKKAL 540
Q + K+ LAR E P+ P T KA+
Sbjct: 483 QCPRKVIKMESEEGKEARLARSSPEQPR-PSTSKAV 517
>gi|109637788 promyelocytic leukemia protein isoform 5 [Homo
sapiens]
Length = 560
Score = 32.3 bits (72), Expect = 1.2
Identities = 31/96 (32%), Positives = 41/96 (42%), Gaps = 12/96 (12%)
Query: 456 EREEAWVKIENLAKANPQYTVYSQASTMSIPV-AMETDGPLF-EDVQMLRKTVKDEAHQA 513
ER +A V+ LA+A P V S +PV A GP + EDV K + Q
Sbjct: 423 ERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQT 482
Query: 514 Q---------KDPKKDRPLARRKSELPQDPHTKKAL 540
Q + K+ LAR E P+ P T KA+
Sbjct: 483 QCPRKVIKMESEEGKEARLARSSPEQPR-PSTSKAV 517
>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
sapiens]
Length = 1912
Score = 32.0 bits (71), Expect = 1.5
Identities = 14/39 (35%), Positives = 21/39 (53%)
Query: 2 PNKNKKEKESPKAGKSGKSSKEGQDTVESEGTSPEEPSS 40
P K KK+K PK K KS ++ ++ E + +EP S
Sbjct: 112 PGKKKKKKLGPKKEKKSKSKRKEEEEEEDDDDDSKEPKS 150
>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
Length = 846
Score = 31.6 bits (70), Expect = 2.0
Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Query: 451 KLKMKEREEAWVKIENLAKANPQYTVYSQASTMSIPVAMETDGPLFEDVQMLRKTVKDEA 510
+LK ++ E ++ +N N + V S A+ETD + E++ K +
Sbjct: 544 ELKTRQGTELLIQSDNDTVINDWFKVLSSTINNQ---AVETDEGIEEEIPDSPGIEKHDK 600
Query: 511 HQAQKDPKKDRPLARRKSELPQDPHTKKALE 541
+ QKDPKK R + + TKK L+
Sbjct: 601 EKEQKDPKKLRSFKVSSIDSSEQKKTKKNLK 631
>gi|222080092 WD repeat domain 91 [Homo sapiens]
Length = 747
Score = 31.2 bits (69), Expect = 2.6
Identities = 36/137 (26%), Positives = 55/137 (40%), Gaps = 31/137 (22%)
Query: 67 ADQEKLF-----IQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEP 121
AD+EK F + +L+Q ++D + L D W ++R S + E
Sbjct: 34 ADKEKGFRVDKIVDQLQQLMQVYDLAA--LRDY-WSYLERRLFSRL------------ED 78
Query: 122 IYPEVVHMFAVNMFR-----TLPPSSNPTGAEFDPEE-DEPTLEAAWPHLQLVYEFFLRF 175
IY +H ++FR T+ + N EF ++ E +A W F L F
Sbjct: 79 IYRPTIHKLKTSLFRFYLVYTIQTNRNDKAQEFFAKQATELQNQAEWKDW-----FVLPF 133
Query: 176 LESPDFQPNIAKKYIDQ 192
L SPD P A + Q
Sbjct: 134 LPSPDTNPTFATYFSRQ 150
>gi|4505183 CD99 antigen isoform a precursor [Homo sapiens]
Length = 185
Score = 31.2 bits (69), Expect = 2.6
Identities = 15/43 (34%), Positives = 19/43 (44%)
Query: 3 NKNKKEKESPKAGKSGKSSKEGQDTVESEGTSPEEPSSPKVPP 45
N+NKK PK +G G V+ E P P+ PK P
Sbjct: 35 NENKKPTAIPKKPSAGDDFDLGDAVVDGENDDPRPPNPPKPMP 77
>gi|112734867 retinitis pigmentosa GTPase regulator interacting
protein 1 [Homo sapiens]
Length = 1286
Score = 31.2 bits (69), Expect = 2.6
Identities = 38/165 (23%), Positives = 72/165 (43%), Gaps = 9/165 (5%)
Query: 389 LISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKL 448
L++DN K+L M S +S+ HW+ + LI L+ + Q D + + L
Sbjct: 373 LLNDNYDKLLESMLDSSDSSSQPHWS---NELIAEQLQQQVSQLQDQLDAELEDKRKVLL 429
Query: 449 KEKLKMKEREEAWVKIEN-LAKANPQYTVYSQASTMSIPVAMETDGPLFEDVQMLRKTVK 507
+ + + E+ +++ N L K + + A+T+S P +++ P + T
Sbjct: 430 ELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQSE-PATHPAVLQENTQI 488
Query: 508 DEAHQAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELASQ 552
+ + ++ KK L++ +EL Q H + LE D L Q
Sbjct: 489 EPSEPKNQEEKK---LSQVLNEL-QVSHAETTLELEKTRDMLILQ 529
>gi|148839376 PWWP domain containing 2 isoform 1 [Homo sapiens]
Length = 590
Score = 31.2 bits (69), Expect = 2.6
Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 9/51 (17%)
Query: 10 ESPKAGKSGKSSKEGQDTVESEGTS---------PEEPSSPKVPPPLLPEL 51
ESP G++ +EG V G+S P E + P+ PPPL+P L
Sbjct: 59 ESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPPLVPPL 109
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,007,536
Number of Sequences: 37866
Number of extensions: 1039639
Number of successful extensions: 5891
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 5755
Number of HSP's gapped (non-prelim): 180
length of query: 555
length of database: 18,247,518
effective HSP length: 107
effective length of query: 448
effective length of database: 14,195,856
effective search space: 6359743488
effective search space used: 6359743488
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.