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Search of human proteins with 24041026
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24041026 neuropilin- and tolloid-like protein 2 precursor
[Homo sapiens]
(525 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24041026 neuropilin- and tolloid-like protein 2 precursor [Ho... 1080 0.0
gi|20373181 neuropilin- and tolloid-like protein 1 isoform 3 pre... 617 e-177
gi|23510396 neuropilin- and tolloid-like protein 1 isoform 2 pre... 617 e-177
gi|20452470 neuropilin- and tolloid-like protein 1 isoform 1 pre... 185 8e-47
gi|126091152 cubilin [Homo sapiens] 129 5e-30
gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens] 125 7e-29
gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens] 125 7e-29
gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens] 125 7e-29
gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens] 125 7e-29
gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens] 125 7e-29
gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens] 125 7e-29
gi|22547221 tolloid-like 1 [Homo sapiens] 115 7e-26
gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom... 115 1e-25
gi|6912724 tolloid-like 2 [Homo sapiens] 110 3e-24
gi|13899255 membrane frizzled-related protein [Homo sapiens] 107 3e-23
gi|66864913 neuropilin 1 isoform c [Homo sapiens] 101 2e-21
gi|66912178 neuropilin 1 isoform b [Homo sapiens] 101 2e-21
gi|182508169 neuropilin 1 isoform a [Homo sapiens] 101 2e-21
gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom... 96 1e-19
gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom... 96 1e-19
gi|72384339 CUB domain containing protein 2 [Homo sapiens] 92 9e-19
gi|157653329 procollagen C-endopeptidase enhancer [Homo sapiens] 83 5e-16
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 81 2e-15
gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens] 77 4e-14
gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens] 77 4e-14
gi|148539844 deleted in malignant brain tumors 1 isoform c precu... 77 4e-14
gi|148539842 deleted in malignant brain tumors 1 isoform b precu... 77 4e-14
gi|148539840 deleted in malignant brain tumors 1 isoform a precu... 77 4e-14
gi|7019483 procollagen C-endopeptidase enhancer 2 [Homo sapiens] 77 5e-14
gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] 70 4e-12
>gi|24041026 neuropilin- and tolloid-like protein 2 precursor [Homo
sapiens]
Length = 525
Score = 1080 bits (2793), Expect = 0.0
Identities = 525/525 (100%), Positives = 525/525 (100%)
Query: 1 MALERLCSVLKVLLITVLVVEGIAVAQKTQDGQNIGIKHIPATQCGIWVRTSNGGHFASP 60
MALERLCSVLKVLLITVLVVEGIAVAQKTQDGQNIGIKHIPATQCGIWVRTSNGGHFASP
Sbjct: 1 MALERLCSVLKVLLITVLVVEGIAVAQKTQDGQNIGIKHIPATQCGIWVRTSNGGHFASP 60
Query: 61 NYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGFSPLIDR 120
NYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGFSPLIDR
Sbjct: 61 NYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGFSPLIDR 120
Query: 121 YCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGILNPIPDCQFE 180
YCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGILNPIPDCQFE
Sbjct: 121 YCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGILNPIPDCQFE 180
Query: 181 LSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVA 240
LSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVA
Sbjct: 181 LSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVA 240
Query: 241 VYDGSSSIENLKAKFCSTVANDVMLKTGIGVIRMWADEGSRLSRFRMLFTSFVEPPCTSS 300
VYDGSSSIENLKAKFCSTVANDVMLKTGIGVIRMWADEGSRLSRFRMLFTSFVEPPCTSS
Sbjct: 241 VYDGSSSIENLKAKFCSTVANDVMLKTGIGVIRMWADEGSRLSRFRMLFTSFVEPPCTSS 300
Query: 301 TFFCHSNMCINNSLVCNGVQNCAYPWDENHCKEKKKAGVFEQITKTHGTIIGITSGIVLV 360
TFFCHSNMCINNSLVCNGVQNCAYPWDENHCKEKKKAGVFEQITKTHGTIIGITSGIVLV
Sbjct: 301 TFFCHSNMCINNSLVCNGVQNCAYPWDENHCKEKKKAGVFEQITKTHGTIIGITSGIVLV 360
Query: 361 LLIISILVQVKQPRKKVMACKTAFNKTGFQEVFDPPHYELFSLRDKEISADLADLSEELD 420
LLIISILVQVKQPRKKVMACKTAFNKTGFQEVFDPPHYELFSLRDKEISADLADLSEELD
Sbjct: 361 LLIISILVQVKQPRKKVMACKTAFNKTGFQEVFDPPHYELFSLRDKEISADLADLSEELD 420
Query: 421 NYQKMRRSSTASRCIHDHHCGSQASSVKQSRTNLSSMELPFRNDFAQPQPMKTFNSTFKK 480
NYQKMRRSSTASRCIHDHHCGSQASSVKQSRTNLSSMELPFRNDFAQPQPMKTFNSTFKK
Sbjct: 421 NYQKMRRSSTASRCIHDHHCGSQASSVKQSRTNLSSMELPFRNDFAQPQPMKTFNSTFKK 480
Query: 481 SSYTFKQGHECPEQALEDRVMEEIPCEIYVRGREDSAQASISIDF 525
SSYTFKQGHECPEQALEDRVMEEIPCEIYVRGREDSAQASISIDF
Sbjct: 481 SSYTFKQGHECPEQALEDRVMEEIPCEIYVRGREDSAQASISIDF 525
>gi|20373181 neuropilin- and tolloid-like protein 1 isoform 3
precursor [Homo sapiens]
Length = 533
Score = 617 bits (1592), Expect = e-177
Identities = 294/510 (57%), Positives = 380/510 (74%), Gaps = 14/510 (2%)
Query: 14 LITVLVVEGIAVAQKTQDGQNIGIKHIPATQCGIWVRTSNGGHFASPNYPDSYPPNKECI 73
++ L++ ++ A K + + + QCG W + + GG F SPNYP YPP++ECI
Sbjct: 10 IVASLIILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECI 69
Query: 74 YILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRST 133
YI+EAAPRQ IEL FDE Y IEPS+EC+FDH+EVRDGPFGFSP+I R+CG ++PP+I+S+
Sbjct: 70 YIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSS 129
Query: 134 GRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGILNPIPDCQFELSGADGIVRSSQV 193
GRF+WIKF +D ELE +GF A+Y+F PDPDF LG L P+P C+FE+ G++GIV S Q+
Sbjct: 130 GRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGA-LKPLPACEFEMGGSEGIVESIQI 188
Query: 194 EQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKA 253
+E K +AVDC W I+A P++KIYLRFLDY+M++SNECKRNFVAVYDGSSS+E+LKA
Sbjct: 189 MKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSSVEDLKA 248
Query: 254 KFCSTVANDVMLKTGIGVIRMWADEGSRLSRFRMLFTSFVEPPCTSSTFFCHSNMCINNS 313
KFCSTVANDVML+TG+GVIRMWADEGSR SRF+MLFTSF EPPC +TFFCHSNMCINN+
Sbjct: 249 KFCSTVANDVMLRTGLGVIRMWADEGSRNSRFQMLFTSFQEPPCEGNTFFCHSNMCINNT 308
Query: 314 LVCNGVQNCAYPWDENHCKEKKKAGVFEQITKTHGTIIGITSGIVLVLLIISILVQVKQP 373
LVCNG+QNC YPWDENHCKEK+K + +Q+T T GT+IG+TS IV++L+IIS++VQ+KQP
Sbjct: 309 LVCNGLQNCVYPWDENHCKEKRKTSLLDQLTNTSGTVIGVTSCIVIILIIISVIVQIKQP 368
Query: 374 RKKVMACKTAFNKTGFQEVFDPPHYELFSLRDKEISADLADLSEELDNYQKMRRSSTASR 433
RKK + K+ F++T FQEVF+PPHYEL +LR +AD AD++++ +NY K+RRSS S+
Sbjct: 369 RKKYVQRKSDFDQTVFQEVFEPPHYELCTLRGTGATADFADVADDFENYHKLRRSS--SK 426
Query: 434 CIHDHHCGSQASSVKQSRTNLSS------MELPFRNDFAQPQPMKTFNSTFKKSSYTFKQ 487
CIHDHHCGSQ SS K SR+NLS+ E+P + PM N K +Y+
Sbjct: 427 CIHDHHCGSQLSSTKGSRSNLSTRDASILTEMPTQPGKPLIPPMNRRNILVMKHNYSQDA 486
Query: 488 GHECPEQALEDRVMEEIPCEIYVRGREDSA 517
C + EE+P + R D A
Sbjct: 487 ADACDIDEI-----EEVPTTSHRLSRHDKA 511
>gi|23510396 neuropilin- and tolloid-like protein 1 isoform 2
precursor [Homo sapiens]
Length = 532
Score = 617 bits (1591), Expect = e-177
Identities = 291/482 (60%), Positives = 369/482 (76%), Gaps = 14/482 (2%)
Query: 42 ATQCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECR 101
+ QCG W + + GG F SPNYP YPP++ECIYI+EAAPRQ IEL FDE Y IEPS+EC+
Sbjct: 37 SVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECK 96
Query: 102 FDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPD 161
FDH+EVRDGPFGFSP+I R+CG ++PP+I+S+GRF+WIKF +D ELE +GF A+Y+F PD
Sbjct: 97 FDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPD 156
Query: 162 PDFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYL 221
PDF LG L P+P C+FE+ G++GIV S Q+ +E K +AVDC W I+A P++KIYL
Sbjct: 157 PDFKDLGA-LKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYL 215
Query: 222 RFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVMLKTGIGVIRMWADEGSR 281
RFLDY+M++SNECKRNFVAVYDGSSS+E+LKAKFCSTVANDVML+TG+GVIRMWADEGSR
Sbjct: 216 RFLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFCSTVANDVMLRTGLGVIRMWADEGSR 275
Query: 282 LSRFRMLFTSFVEPPCTSSTFFCHSNMCINNSLVCNGVQNCAYPWDENHCKEKKKAGVFE 341
SRF+MLFTSF EPPC +TFFCHSNMCINN+LVCNG+QNC YPWDENHCKEK+K + +
Sbjct: 276 NSRFQMLFTSFQEPPCEGNTFFCHSNMCINNTLVCNGLQNCVYPWDENHCKEKRKTSLLD 335
Query: 342 QITKTHGTIIGITSGIVLVLLIISILVQVKQPRKKVMACKTAFNKTGFQEVFDPPHYELF 401
Q+T T GT+IG+TS IV++L+IIS++VQ+KQPRKK + K+ F++T FQEVF+PPHYEL
Sbjct: 336 QLTNTSGTVIGVTSCIVIILIIISVIVQIKQPRKKYVQRKSDFDQTVFQEVFEPPHYELC 395
Query: 402 SLRDKEISADLADLSEELDNYQKMRRSSTASRCIHDHHCGSQASSVKQSRTNLSS----- 456
+LR +AD AD++++ +NY K+RRSS S+CIHDHHCGSQ SS K SR+NLS+
Sbjct: 396 TLRGTGATADFADVADDFENYHKLRRSS--SKCIHDHHCGSQLSSTKGSRSNLSTRDASI 453
Query: 457 -MELPFRNDFAQPQPMKTFNSTFKKSSYTFKQGHECPEQALEDRVMEEIPCEIYVRGRED 515
E+P + PM N K +Y+ C + EE+P + R D
Sbjct: 454 LTEMPTQPGKPLIPPMNRRNILVMKHNYSQDAADACDIDEI-----EEVPTTSHRLSRHD 508
Query: 516 SA 517
A
Sbjct: 509 KA 510
>gi|20452470 neuropilin- and tolloid-like protein 1 isoform 1
precursor [Homo sapiens]
Length = 156
Score = 185 bits (470), Expect = 8e-47
Identities = 78/120 (65%), Positives = 100/120 (83%)
Query: 42 ATQCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECR 101
+ QCG W + + GG F SPNYP YPP++ECIYI+EAAPRQ IEL FDE Y IEPS+EC+
Sbjct: 37 SVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECK 96
Query: 102 FDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPD 161
FDH+EVRDGPFGFSP+I R+CG ++PP+I+S+GRF+WIKF +D ELE +GF A+Y+F P+
Sbjct: 97 FDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPE 156
Score = 36.2 bits (82), Expect = 0.075
Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
Query: 206 DCIWTIKATPKAKIYLRFLD-YQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVM 264
+CI+ I+A P+ I L F + Y +E S ECK + + V DG + +FC V+
Sbjct: 66 ECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVI 125
Query: 265 LKTG 268
+G
Sbjct: 126 KSSG 129
>gi|126091152 cubilin [Homo sapiens]
Length = 3623
Score = 129 bits (325), Expect = 5e-30
Identities = 78/276 (28%), Positives = 143/276 (51%), Gaps = 27/276 (9%)
Query: 25 VAQKTQDGQNIGIKH-IPATQCG--IWVRTSNG-GHFASPNYPDSYPPNKECIYILEAAP 80
++ + +GQ IK+ + CG +++ ++ G+ SPN+P +YPP+ +CI+IL A P
Sbjct: 2196 ISDHSNEGQGFKIKYEAKSLACGGNVYIHDADSAGYVTSPNHPHNYPPHADCIWILAAPP 2255
Query: 81 RQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIK 140
RI+L F++ + IE + C ++LE+RDG +P++ ++CG P S+G M+++
Sbjct: 2256 ETRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAPILSKFCGTSLPSSQWSSGEVMYLR 2315
Query: 141 FSSDEELEGLGFRAKYSFIPDPDFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTK 200
F SD +GF+AKYS I C + G G+V S T
Sbjct: 2316 FRSDNSPTHVGFKAKYS----------------IAQCGGRVPGQSGVVESI----GHPTL 2355
Query: 201 P-GQAVDCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFC-ST 258
P + C W ++ + + F D+ +++S+ C+++FV ++D +S N+ ++C +T
Sbjct: 2356 PYRDNLFCEWHLQGLSGHYLTISFEDFNLQNSSGCEKDFVEIWDNHTS-GNILGRYCGNT 2414
Query: 259 VANDVMLKTGIGVIRMWADEGSRLSRFRMLFTSFVE 294
+ + + + V+R D S FR+ F S +E
Sbjct: 2415 IPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSME 2450
Score = 102 bits (253), Expect = 1e-21
Identities = 74/257 (28%), Positives = 116/257 (45%), Gaps = 19/257 (7%)
Query: 31 DGQNIGIKHIPATQCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDE 90
+G I + I A + T + G F SPN+P++YP N ECIY + Q I + F
Sbjct: 1033 EGFLINYEAISAATACLQDYTDDLGTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTN 1092
Query: 91 HYYIEPSFECRFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGL 150
E D LE+RDG + SPL+ + G PP I S +W+KF SD+ +
Sbjct: 1093 FSLEEAIGNYYTDFLEIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQ----I 1148
Query: 151 GFRAKYSFIPDPDFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWT 210
R+ +S D T GG L+ + G S + +C W
Sbjct: 1149 DTRSGFSAYWDGSSTGCGG----------NLTTSSGTFISPNYPMPYY----HSSECYWW 1194
Query: 211 IKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVMLKTGIG 270
+K++ + L F D+ +EH C +++AVYDG SS +L + C ++ +G
Sbjct: 1195 LKSSHGSAFELEFKDFHLEHHPNCTLDYLAVYDGPSSNSHLLTQLCGDEKPPLIRSSGDS 1254
Query: 271 V-IRMWADEGSRLSRFR 286
+ I++ DEG + F+
Sbjct: 1255 MFIKLRTDEGQQGRGFK 1271
Score = 100 bits (250), Expect = 2e-21
Identities = 67/209 (32%), Positives = 101/209 (48%), Gaps = 33/209 (15%)
Query: 42 ATQCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECR 101
+T CG + TS+G F SPNYP Y + EC + L+++ EL F + +++E C
Sbjct: 1162 STGCGGNLTTSSGT-FISPNYPMPYYHSSECYWWLKSSHGSAFELEFKD-FHLEHHPNCT 1219
Query: 102 FDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYS---- 157
D+L V DGP S L+ + CG + PPLIRS+G M+IK +DE +G GF+A+Y
Sbjct: 1220 LDYLAVYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAEYRQTCE 1279
Query: 158 --FIPDPDFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATP 215
I + + L I P P + + C WTI+AT
Sbjct: 1280 NVVIVNQTYGILESIGYPNPYSENQ-------------------------HCNWTIRATT 1314
Query: 216 KAKIYLRFLDYQMEHSNECKRNFVAVYDG 244
+ FL + +EH C +++ +YDG
Sbjct: 1315 GNTVNYTFLAFDLEHHINCSTDYLELYDG 1343
Score = 100 bits (248), Expect = 4e-21
Identities = 72/258 (27%), Positives = 119/258 (46%), Gaps = 26/258 (10%)
Query: 3 LERLCSVLKVLLITVLVVEGIAVAQKTQDG---QNIGIKHIPATQCGIWVRTSNGGHFAS 59
L R C + L +V G ++ + Q G QN G + CG + TS+ +S
Sbjct: 1577 LARTCG--REQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQFRQACGGHILTSSFDTVSS 1634
Query: 60 PNYPDSYPPNKECIYILEAAPR-QRIELTFDEHYYIEPSFECRFDHLEVRDGPFGFSPLI 118
P +P +YP N+ C +I++A P I L+F H+ +E S C D +E+ DG +PL
Sbjct: 1635 PRFPANYPNNQNCSWIIQAQPPLNHITLSFT-HFELERSTTCARDFVEILDGGHEDAPLR 1693
Query: 119 DRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGILNPIPDCQ 178
RYCG P I S + ++F SD + GF + + C
Sbjct: 1694 GRYCGTDMPHPITSFSSALTLRFVSDSSISAGGFHTT--------------VTASVSACG 1739
Query: 179 FELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNECKRNF 238
A+GI S V+C+W I ++P ++ L F+ +Q+E S +C R+F
Sbjct: 1740 GTFYMAEGIFNSPGYPDIYPPN----VECVWNIVSSPGNRLQLSFISFQLEDSQDCSRDF 1795
Query: 239 VAVYDGSSSIENLKAKFC 256
V + +G+++ +L ++C
Sbjct: 1796 VEIREGNAT-GHLVGRYC 1812
Score = 99.0 bits (245), Expect = 9e-21
Identities = 70/243 (28%), Positives = 106/243 (43%), Gaps = 34/243 (13%)
Query: 55 GHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGF 114
G F+SP +P+ YPPNKECI+ + P I+LT + + +E C FD LE+ GP
Sbjct: 1400 GSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHD-FDVEYHSRCNFDVLEIYGGPDFH 1458
Query: 115 SPLIDRYCGVKSP--PL-IRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGIL 171
SP I + C +SP P+ + STG + I+F +D + G GF A +
Sbjct: 1459 SPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASW--------------- 1503
Query: 172 NPIPDCQFELSGADGIVRSSQVEQEEKTKPG---QAVDCIWTIKATPKAKIYLRFLDYQM 228
Q G GI ++ E P DC W I+ ++ L F D+ +
Sbjct: 1504 ------QAVTGGCGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDL 1557
Query: 229 EHSNECKRNFVAVYDGSSSIENLKAKFC--STVANDVMLKTGIGVIRMWADEGSRLSRFR 286
E + C + YDG SS + A+ C +AN ++ +R + + FR
Sbjct: 1558 EPQDSC----IMAYDGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFR 1613
Query: 287 MLF 289
F
Sbjct: 1614 AQF 1616
Score = 91.7 bits (226), Expect = 2e-18
Identities = 67/248 (27%), Positives = 109/248 (43%), Gaps = 25/248 (10%)
Query: 44 QCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFD 103
+CG + T G SP YP +YPP ++C++I+ +P + TF +E +C D
Sbjct: 589 ECG-GILTGPYGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGT-LSLEHHDDCNKD 646
Query: 104 HLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPD 163
+LE+RDGP PL+ ++C S P +++TG F I F SD ++ GF Y P D
Sbjct: 647 YLEIRDGPLYQDPLLGKFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITYLTSPS-D 705
Query: 164 FTYLGGILNPIPDCQF-ELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLR 222
G +P + ELSG R C++ +K +I +
Sbjct: 706 LRCGGNYTDPEGELFLPELSGPFTHTR----------------QCVYMMKQPQGEQIQIN 749
Query: 223 FLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCST-VANDVMLKTGIGVIRMWADEGSR 281
F +++ ++ +N++ V DG E L K C + + T IR D
Sbjct: 750 FTHVELQCQSDSSQNYIEVRDG----ETLLGKVCGNGTISHIKSITNSVWIRFKIDASVE 805
Query: 282 LSRFRMLF 289
+ FR ++
Sbjct: 806 KASFRAVY 813
Score = 86.7 bits (213), Expect = 5e-17
Identities = 59/205 (28%), Positives = 90/205 (43%), Gaps = 23/205 (11%)
Query: 55 GHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGF 114
G F SP YPD YPPN EC++ + ++P R++L+F + +E S +C D +E+R+G
Sbjct: 1747 GIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFIS-FQLEDSQDCSRDFVEIREGN-AT 1804
Query: 115 SPLIDRYCGVKSPPLIRS-TGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGILNP 173
L+ RYCG P S G +W++F SD G GF+A + I D
Sbjct: 1805 GHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATFMKIFGND---------- 1854
Query: 174 IPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNE 233
+ G G V S + WT+ ++ R L+ +E
Sbjct: 1855 ------NIVGTHGKVASPFWPENYPHNSNYQ----WTVNVNASHVVHGRILEMDIEEIQN 1904
Query: 234 CKRNFVAVYDGSSSIENLKAKFCST 258
C + + +YDG S L +C T
Sbjct: 1905 CYYDKLRIYDGPSIHARLIGAYCGT 1929
Score = 85.5 bits (210), Expect = 1e-16
Identities = 56/220 (25%), Positives = 99/220 (45%), Gaps = 18/220 (8%)
Query: 53 NGGHFASPNYPDS-YPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGP 111
+ G SP Y + YP + C+Y + + + IEL F + + + PS C D+L + DG
Sbjct: 3044 SSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSD-FDVVPSTSCSHDYLAIYDGA 3102
Query: 112 FGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGIL 171
PL+ ++CG K PP ++S+ M + F +D G++ + L
Sbjct: 3103 NTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMSFR-----------QTL 3151
Query: 172 NPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHS 231
P C L+G++ S + + + ++C+W I A I+L F + +E +
Sbjct: 3152 GPQQGCGGYLTGSNNTFASP--DSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAA 3209
Query: 232 N---ECKRNFVAVYDGSSSIENLKAKFCSTVANDVMLKTG 268
+ C ++V +YDG S NL FC + + +G
Sbjct: 3210 STRQRCLYDYVKLYDGDSENANLAGTFCGSTVPAPFISSG 3249
Score = 84.3 bits (207), Expect = 2e-16
Identities = 62/242 (25%), Positives = 99/242 (40%), Gaps = 27/242 (11%)
Query: 55 GHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGF 114
G+ SP +PD+Y +K+C L A I L F IE S ECR D LEVR+G
Sbjct: 3404 GNLRSPGWPDNYDNDKDCTVTLTAPQNHTISLFFHS-LGIENSVECRNDFLEVRNGSNSN 3462
Query: 115 SPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGILNPI 174
SPL+ +YCG P + S ++++F SD G+ ++ P
Sbjct: 3463 SPLLGKYCGTLLPNPVFSQNNELYLRFKSDSVTSDRGYEIIWTSSP-------------- 3508
Query: 175 PDCQFELSGADGIVRSSQVEQEEKTKPGQAVD---CIWTIKATPKAKIYLRFLDYQMEHS 231
SG G + + PG + C W + A + + F ++
Sbjct: 3509 -------SGCGGTLYGDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFYFISIDDP 3561
Query: 232 NECKRNFVAVYDGSSSIENLKAKFC--STVANDVMLKTGIGVIRMWADEGSRLSRFRMLF 289
+C +N++ +YDG ++ +C T + + I+ AD R S FR+ +
Sbjct: 3562 GDCVQNYLTLYDGPNASSPSSGPYCGGDTSIAPFVASSNQVFIKFHADYARRPSAFRLTW 3621
Query: 290 TS 291
S
Sbjct: 3622 DS 3623
Score = 83.2 bits (204), Expect = 5e-16
Identities = 75/263 (28%), Positives = 118/263 (44%), Gaps = 29/263 (11%)
Query: 5 RLCSVLKVLLITVLVVEGIAVAQKTQDG-QNIGIK-HIPATQCGIWVRTSNGGHFASPNY 62
RLC K L V+ + + T + ++IG T CG ++ + G SPNY
Sbjct: 2647 RLCGPSKPTLPLVIPYSQVWIHFVTNERVEHIGFHAKYSFTDCG-GIQIGDSGVITSPNY 2705
Query: 63 PDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGFSPLIDRYC 122
P++Y C +LEA I LTF + + IEP C +D + VR+G SP+I +YC
Sbjct: 2706 PNAYDSLTHCSSLLEAPQGHTITLTFSD-FDIEPHTTCAWDSVTVRNGGSPESPIIGQYC 2764
Query: 123 GVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGILNPIPDCQFELS 182
G +P I+S + + F+SD L+G GF A + + GGI +
Sbjct: 2765 GNSNPRTIQSGSNQLVVTFNSDHSLQGGGFYATW----NTQTLGCGGIFH---------- 2810
Query: 183 GADGIVRSSQVEQE--EKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHS--NECKRNF 238
+G +RS Q E ++ C WT + + F + + S +C+ +F
Sbjct: 2811 SDNGTIRSPHWPQNFPENSR------CSWTAITHKSKHLEISFDNNFLIPSGDGQCQNSF 2864
Query: 239 VAVYDGSSSIEN-LKAKFCSTVA 260
V V+ G+ ++ L A C VA
Sbjct: 2865 VKVWAGTEEVDKALLATGCGNVA 2887
Score = 80.1 bits (196), Expect = 5e-15
Identities = 56/212 (26%), Positives = 94/212 (44%), Gaps = 25/212 (11%)
Query: 51 TSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEP----SFECRFDHLE 106
T G+ SPNYP Y N C Y++EA P + LTF +++E + C D +
Sbjct: 2925 TGPSGYIISPNYPKQYDNNMNCTYVIEANPLSVVLLTF-VSFHLEARSAVTGSCVNDGVH 2983
Query: 107 VRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTY 166
+ G S CG + P + G + + F S+E++ GF+ Y I
Sbjct: 2984 IIRGYSVMSTPFATVCGDEMPAPLTIAGPVL-LNFYSNEQITDFGFKFSYRIIS------ 3036
Query: 167 LGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDY 226
GG+ N + GI+ S + + C++TI + I L+F D+
Sbjct: 3037 CGGVFN----------FSSGIITSPAYSYADYPND---MHCLYTITVSDDKVIELKFSDF 3083
Query: 227 QMEHSNECKRNFVAVYDGSSSIENLKAKFCST 258
+ S C +++A+YDG+++ + L KFC +
Sbjct: 3084 DVVPSTSCSHDYLAIYDGANTSDPLLGKFCGS 3115
Score = 73.9 bits (180), Expect = 3e-13
Identities = 59/223 (26%), Positives = 98/223 (43%), Gaps = 24/223 (10%)
Query: 45 CGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYI-EPSFEC-RF 102
CG ++ G SP YP++YP N C + + I + F++ + I C +
Sbjct: 2092 CGGYLHADRG-IITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQG 2150
Query: 103 DHLEVRDGPFGFSPLID------RYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKY 156
D+L +R+GP SP + +CG + + ++ M+++F SD EG GF+ KY
Sbjct: 2151 DYLVLRNGPDICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKY 2210
Query: 157 SFIPDPDFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPK 216
+ GG + AD + P DCIW + A P+
Sbjct: 2211 ----EAKSLACGG--------NVYIHDADSAGYVTSPNHPHNYPP--HADCIWILAAPPE 2256
Query: 217 AKIYLRFLD-YQMEHSNECKRNFVAVYDGSSSIENLKAKFCST 258
+I L+F D + +E + C N++ + DG S + +KFC T
Sbjct: 2257 TRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAPILSKFCGT 2299
Score = 69.7 bits (169), Expect = 6e-12
Identities = 51/230 (22%), Positives = 98/230 (42%), Gaps = 22/230 (9%)
Query: 40 IPATQCGIWVRTSNGGH-FASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSF 98
+P CG + NG + SP+ Y + C ++++ + + +TF + +E
Sbjct: 469 VPQQVCGESLSGINGSFSYRSPDV--GYVHDVNCFWVIKTEMGKVLRITFT-FFRLESMD 525
Query: 99 ECRFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSF 158
C + L+V DG + + R+CG P + S+ ++ S+ G GF ++
Sbjct: 526 NCPHEFLQVYDGDSSSAFQLGRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWE- 584
Query: 159 IPDPDFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAK 218
P+C L+G G ++S PG+ DC+W + +P
Sbjct: 585 -------------TQQPECGGILTGPYGSIKSP--GYPGNYPPGR--DCVWIVVTSPDLL 627
Query: 219 IYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVMLKTG 268
+ F +EH ++C ++++ + DG + L KFC+T + + TG
Sbjct: 628 VTFTFGTLSLEHHDDCNKDYLEIRDGPLYQDPLLGKFCTTFSVPPLQTTG 677
Score = 68.9 bits (167), Expect = 1e-11
Identities = 59/228 (25%), Positives = 96/228 (42%), Gaps = 24/228 (10%)
Query: 41 PATQCGIWVRTSNGGHFASPNYPDS--YPPNKECIYILEAAPRQRIELTFDEHYYIEPSF 98
P CG ++ SN FASP+ + Y N C++I+ A + I LTF+ S
Sbjct: 3153 PQQGCGGYLTGSNNT-FASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAAST 3211
Query: 99 E--CRFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKY 156
C +D++++ DG + L +CG P S+G F+ ++F SD LE GF A Y
Sbjct: 3212 RQRCLYDYVKLYDGDSENANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLEREGFNATY 3271
Query: 157 SFIPDPDFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVD-CIWTIKATP 215
+ + P GG N Q + + P C W I + P
Sbjct: 3272 TIMDMP----CGGTYNATWTPQ-------------NISSPNSSDPDVPFSICTWVIDSPP 3314
Query: 216 KAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDV 263
++ + Q+ S +C +N++ + D N + +FC A+ V
Sbjct: 3315 HQQVKITVWALQLT-SQDCTQNYLQLQDSPQGHGNSRFQFCGRNASAV 3361
Score = 68.6 bits (166), Expect = 1e-11
Identities = 53/202 (26%), Positives = 81/202 (40%), Gaps = 21/202 (10%)
Query: 55 GHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGF 114
G SP +P+ YP + C + + Q I L F + I S C D++E+
Sbjct: 825 GVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTV-FEIGSSAHCETDYVEIGSSSILG 883
Query: 115 SPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGILNPI 174
SP +YCG P I S F+++ F E GF AK+S D
Sbjct: 884 SPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKFS---AEDLA--------- 931
Query: 175 PDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNEC 234
C L+ + G ++S P ++C W I P I+L F + +E C
Sbjct: 932 --CGEILTESTGTIQS---PGHPNVYP-HGINCTWHILVQPNHLIHLMFETFHLEFHYNC 985
Query: 235 KRNFVAVYDGSSSIENLKAKFC 256
+++ VYD S E ++C
Sbjct: 986 TNDYLEVYDTDS--ETSLGRYC 1005
Score = 68.6 bits (166), Expect = 1e-11
Identities = 40/113 (35%), Positives = 61/113 (53%), Gaps = 3/113 (2%)
Query: 45 CGIWVRTSNGGHFA-SPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFD 103
CG ++RT + F SP +PDSY +C ++++A P +EL IE C +D
Sbjct: 1978 CGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQA-PDSTVELNILS-LDIESHRTCAYD 2035
Query: 104 HLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKY 156
L +RDG + + CG + P IRSTG +M+I+F+SD + GF A +
Sbjct: 2036 SLVIRDGDNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASF 2088
Score = 68.6 bits (166), Expect = 1e-11
Identities = 59/217 (27%), Positives = 91/217 (41%), Gaps = 27/217 (12%)
Query: 45 CGIWVRTSNGGHFASPNYPD--SYPPNKECIYILEAAPRQRIELTFD-EHYYIEPSFECR 101
CG + + G+F SP Y +Y N C + L + ++ E +Y+E +C+
Sbjct: 2570 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSISIHFEDFYLESHQDCQ 2629
Query: 102 FDHLEVRDGPFGFSPLIDRYCGVKSP--PLIRSTGRFMWIKFSSDEELEGLGFRAKYSFI 159
FD LE R G PL+ R CG P PL+ + +WI F ++E +E +GF AKYSF
Sbjct: 2630 FDVLEFRVGD-ADGPLMWRLCGPSKPTLPLVIPYSQ-VWIHFVTNERVEHIGFHAKYSF- 2686
Query: 160 PDPDFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKI 219
DC G G++ S + C ++A I
Sbjct: 2687 ---------------TDCGGIQIGDSGVITSPNYPNAYDS----LTHCSSLLEAPQGHTI 2727
Query: 220 YLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFC 256
L F D+ +E C + V V +G S + ++C
Sbjct: 2728 TLTFSDFDIEPHTTCAWDSVTVRNGGSPESPIIGQYC 2764
Score = 67.8 bits (164), Expect = 2e-11
Identities = 53/207 (25%), Positives = 89/207 (42%), Gaps = 29/207 (14%)
Query: 55 GHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGF 114
G SPNYP Y N +C +++ R+ L F + + +EP C + DG
Sbjct: 1519 GEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTD-FDLEPQDSC----IMAYDGLSST 1573
Query: 115 SPLIDRYCGVK--SPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGILN 172
+ R CG + + P++ S+G ++++F S + GFRA++ GG +
Sbjct: 1574 MSRLARTCGREQLANPIV-SSGNSLFLRFQSGPSRQNRGFRAQFR-------QACGGHI- 1624
Query: 173 PIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAK-IYLRFLDYQMEHS 231
L+ + V S + +C W I+A P I L F +++E S
Sbjct: 1625 --------LTSSFDTVSSPRFPANYPNNQ----NCSWIIQAQPPLNHITLSFTHFELERS 1672
Query: 232 NECKRNFVAVYDGSSSIENLKAKFCST 258
C R+FV + DG L+ ++C T
Sbjct: 1673 TTCARDFVEILDGGHEDAPLRGRYCGT 1699
Score = 65.9 bits (159), Expect = 9e-11
Identities = 56/212 (26%), Positives = 93/212 (43%), Gaps = 35/212 (16%)
Query: 51 TSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDG 110
T G P + ++C+Y+++ ++I++ F H ++ + +++EVRDG
Sbjct: 713 TDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFT-HVELQCQSDSSQNYIEVRDG 771
Query: 111 PFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGI 170
L+ + CG + I+S +WI+F D +E FRA Y
Sbjct: 772 ----ETLLGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFRAVYQVA----------- 816
Query: 171 LNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEH 230
C EL+G +G++RS PG+ C WTI I L F +++
Sbjct: 817 ------CGDELTG-EGVIRSPFF---PNVYPGERT-CRWTIHQPQSQVILLNFTVFEIGS 865
Query: 231 SNECKRNFVAVYDGSSSI----ENLKAKFCST 258
S C+ ++V + GSSSI EN K+C T
Sbjct: 866 SAHCETDYVEI--GSSSILGSPEN--KKYCGT 893
Score = 65.9 bits (159), Expect = 9e-11
Identities = 56/203 (27%), Positives = 85/203 (41%), Gaps = 24/203 (11%)
Query: 55 GHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGF 114
G S YP+ Y N+ C + + A + TF + +E C D+LE+ DGP
Sbjct: 1289 GILESIGYPNPYSENQHCNWTIRATTGNTVNYTFLA-FDLEHHINCSTDYLELYDGP--- 1344
Query: 115 SPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGILNPI 174
+ RYCGV PP +T + + +D G+G R K F Y
Sbjct: 1345 -RQMGRYCGVDLPPPGSTTSSKLQVLLLTD----GVGRREK--GFQMQWFVY-------- 1389
Query: 175 PDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNEC 234
C ELSGA G S + P + +CIW I+ P + I L D+ +E+ + C
Sbjct: 1390 -GCGGELSGATGSFSSPGF--PNRYPPNK--ECIWYIRTDPGSSIQLTIHDFDVEYHSRC 1444
Query: 235 KRNFVAVYDGSSSIENLKAKFCS 257
+ + +Y G A+ C+
Sbjct: 1445 NFDVLEIYGGPDFHSPRIAQLCT 1467
Score = 65.5 bits (158), Expect = 1e-10
Identities = 57/220 (25%), Positives = 87/220 (39%), Gaps = 20/220 (9%)
Query: 55 GHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGF 114
G ASP +P++YP N + + + E IE C +D L + DGP
Sbjct: 1861 GKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILE-MDIEEIQNCYYDKLRIYDGPSIH 1919
Query: 115 SPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGILNPI 174
+ LI YCG ++ STG + F SD + G GF ++ + PD G+L I
Sbjct: 1920 ARLIGAYCGTQTES-FSSTGNSLTFHFYSDSSISGKGFLLEWFAVDAPD-----GVLPTI 1973
Query: 175 PDCQFELSGADGIVRSSQVEQEEKTKPG------QAVDCIWTIKATPKAKIYLRFLDYQM 228
G +R+ PG VDC W I+A P + + L L +
Sbjct: 1974 AP-----GACGGFLRTGDA-PVFLFSPGWPDSYSNRVDCTWLIQA-PDSTVELNILSLDI 2026
Query: 229 EHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVMLKTG 268
E C + + + DG +++ A C + TG
Sbjct: 2027 ESHRTCAYDSLVIRDGDNNLAQQLAVLCGREIPGPIRSTG 2066
Score = 61.6 bits (148), Expect = 2e-09
Identities = 52/185 (28%), Positives = 82/185 (44%), Gaps = 20/185 (10%)
Query: 55 GHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDE-HYYIEPSFECRFDHLEVRDGPFG 113
G F SPNYP+ P + C + + A +RI L F+ PS C +H+ V +G
Sbjct: 2461 GTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRLATHPS--CNNEHVIVFNGIRS 2518
Query: 114 FSPLIDRYC-GVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGILN 172
SP +++ C V I+S+G M + F +D GF A Y+ D GG L
Sbjct: 2519 NSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSED---AVCGGSLP 2575
Query: 173 PIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPK--AKIYLRFLDYQMEH 230
P+ F G DG+ S + ++C WT+ + + I + F D+ +E
Sbjct: 2576 NTPEGNFTSPGYDGVRNYS-----------RNLNCEWTLSNPNQGNSSISIHFEDFYLES 2624
Query: 231 SNECK 235
+C+
Sbjct: 2625 HQDCQ 2629
Score = 61.2 bits (147), Expect = 2e-09
Identities = 36/111 (32%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
Query: 49 VRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVR 108
+ T + G SP +P+ YP C + + P I L F E +++E + C D+LEV
Sbjct: 935 ILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMF-ETFHLEFHYNCTNDYLEVY 993
Query: 109 DGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFI 159
D S + RYCG PP + S+G + + F +D +L GF Y I
Sbjct: 994 DTDSETS--LGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINYEAI 1042
>gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]
Length = 909
Score = 125 bits (315), Expect = 7e-29
Identities = 73/237 (30%), Positives = 121/237 (51%), Gaps = 24/237 (10%)
Query: 41 PATQCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAA-PRQRIELTFDEHYYIEPSFE 99
P CG + + + G+ SP YP YP ++ C +I+ A P Q+I L F+ H+ IE +
Sbjct: 24 PDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIE-KHD 82
Query: 100 CRFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFI 159
C++D +E+RDG + L+ ++CG +PP I S+G ++IKF+SD +G GF +Y
Sbjct: 83 CKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIF 142
Query: 160 PDPDFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKI 219
DC + +G + S + K +DC +TI A PK +I
Sbjct: 143 KTGS-----------EDCSKNFTSPNGTIESPGFPE----KYPHNLDCTFTILAKPKMEI 187
Query: 220 YLRFLDYQMEH------SNECKRNFVAVYDGSSSIENLKAKFCST-VANDVMLKTGI 269
L+FL + +EH +CK +++ ++DG + L K+C T +++ TGI
Sbjct: 188 ILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGI 244
Score = 69.3 bits (168), Expect = 8e-12
Identities = 38/114 (33%), Positives = 61/114 (53%), Gaps = 5/114 (4%)
Query: 51 TSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFD----EHYYIEPSF-ECRFDHL 105
TS G SP +P+ YP N +C + + A P+ I L F EH ++ +C++D L
Sbjct: 154 TSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWL 213
Query: 106 EVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFI 159
++ DG PLI +YCG K+P +RS+ + + F +D + GF A+Y +
Sbjct: 214 DIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
>gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens]
Length = 901
Score = 125 bits (315), Expect = 7e-29
Identities = 73/237 (30%), Positives = 121/237 (51%), Gaps = 24/237 (10%)
Query: 41 PATQCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAA-PRQRIELTFDEHYYIEPSFE 99
P CG + + + G+ SP YP YP ++ C +I+ A P Q+I L F+ H+ IE +
Sbjct: 24 PDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIE-KHD 82
Query: 100 CRFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFI 159
C++D +E+RDG + L+ ++CG +PP I S+G ++IKF+SD +G GF +Y
Sbjct: 83 CKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIF 142
Query: 160 PDPDFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKI 219
DC + +G + S + K +DC +TI A PK +I
Sbjct: 143 KTGS-----------EDCSKNFTSPNGTIESPGFPE----KYPHNLDCTFTILAKPKMEI 187
Query: 220 YLRFLDYQMEH------SNECKRNFVAVYDGSSSIENLKAKFCST-VANDVMLKTGI 269
L+FL + +EH +CK +++ ++DG + L K+C T +++ TGI
Sbjct: 188 ILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGI 244
Score = 69.3 bits (168), Expect = 8e-12
Identities = 38/114 (33%), Positives = 61/114 (53%), Gaps = 5/114 (4%)
Query: 51 TSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFD----EHYYIEPSF-ECRFDHL 105
TS G SP +P+ YP N +C + + A P+ I L F EH ++ +C++D L
Sbjct: 154 TSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWL 213
Query: 106 EVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFI 159
++ DG PLI +YCG K+P +RS+ + + F +D + GF A+Y +
Sbjct: 214 DIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
>gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens]
Length = 931
Score = 125 bits (315), Expect = 7e-29
Identities = 73/237 (30%), Positives = 121/237 (51%), Gaps = 24/237 (10%)
Query: 41 PATQCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAA-PRQRIELTFDEHYYIEPSFE 99
P CG + + + G+ SP YP YP ++ C +I+ A P Q+I L F+ H+ IE +
Sbjct: 24 PDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIE-KHD 82
Query: 100 CRFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFI 159
C++D +E+RDG + L+ ++CG +PP I S+G ++IKF+SD +G GF +Y
Sbjct: 83 CKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIF 142
Query: 160 PDPDFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKI 219
DC + +G + S + K +DC +TI A PK +I
Sbjct: 143 KTGS-----------EDCSKNFTSPNGTIESPGFPE----KYPHNLDCTFTILAKPKMEI 187
Query: 220 YLRFLDYQMEH------SNECKRNFVAVYDGSSSIENLKAKFCST-VANDVMLKTGI 269
L+FL + +EH +CK +++ ++DG + L K+C T +++ TGI
Sbjct: 188 ILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGI 244
Score = 69.3 bits (168), Expect = 8e-12
Identities = 38/114 (33%), Positives = 61/114 (53%), Gaps = 5/114 (4%)
Query: 51 TSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFD----EHYYIEPSF-ECRFDHL 105
TS G SP +P+ YP N +C + + A P+ I L F EH ++ +C++D L
Sbjct: 154 TSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWL 213
Query: 106 EVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFI 159
++ DG PLI +YCG K+P +RS+ + + F +D + GF A+Y +
Sbjct: 214 DIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
>gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens]
Length = 555
Score = 125 bits (315), Expect = 7e-29
Identities = 73/237 (30%), Positives = 121/237 (51%), Gaps = 24/237 (10%)
Query: 41 PATQCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAA-PRQRIELTFDEHYYIEPSFE 99
P CG + + + G+ SP YP YP ++ C +I+ A P Q+I L F+ H+ IE +
Sbjct: 24 PDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIE-KHD 82
Query: 100 CRFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFI 159
C++D +E+RDG + L+ ++CG +PP I S+G ++IKF+SD +G GF +Y
Sbjct: 83 CKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIF 142
Query: 160 PDPDFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKI 219
DC + +G + S + K +DC +TI A PK +I
Sbjct: 143 KTGS-----------EDCSKNFTSPNGTIESPGFPE----KYPHNLDCTFTILAKPKMEI 187
Query: 220 YLRFLDYQMEH------SNECKRNFVAVYDGSSSIENLKAKFCST-VANDVMLKTGI 269
L+FL + +EH +CK +++ ++DG + L K+C T +++ TGI
Sbjct: 188 ILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGI 244
Score = 69.3 bits (168), Expect = 8e-12
Identities = 38/114 (33%), Positives = 61/114 (53%), Gaps = 5/114 (4%)
Query: 51 TSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFD----EHYYIEPSF-ECRFDHL 105
TS G SP +P+ YP N +C + + A P+ I L F EH ++ +C++D L
Sbjct: 154 TSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWL 213
Query: 106 EVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFI 159
++ DG PLI +YCG K+P +RS+ + + F +D + GF A+Y +
Sbjct: 214 DIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
>gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens]
Length = 906
Score = 125 bits (315), Expect = 7e-29
Identities = 73/237 (30%), Positives = 121/237 (51%), Gaps = 24/237 (10%)
Query: 41 PATQCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAA-PRQRIELTFDEHYYIEPSFE 99
P CG + + + G+ SP YP YP ++ C +I+ A P Q+I L F+ H+ IE +
Sbjct: 24 PDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIE-KHD 82
Query: 100 CRFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFI 159
C++D +E+RDG + L+ ++CG +PP I S+G ++IKF+SD +G GF +Y
Sbjct: 83 CKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIF 142
Query: 160 PDPDFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKI 219
DC + +G + S + K +DC +TI A PK +I
Sbjct: 143 KTGS-----------EDCSKNFTSPNGTIESPGFPE----KYPHNLDCTFTILAKPKMEI 187
Query: 220 YLRFLDYQMEH------SNECKRNFVAVYDGSSSIENLKAKFCST-VANDVMLKTGI 269
L+FL + +EH +CK +++ ++DG + L K+C T +++ TGI
Sbjct: 188 ILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGI 244
Score = 69.3 bits (168), Expect = 8e-12
Identities = 38/114 (33%), Positives = 61/114 (53%), Gaps = 5/114 (4%)
Query: 51 TSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFD----EHYYIEPSF-ECRFDHL 105
TS G SP +P+ YP N +C + + A P+ I L F EH ++ +C++D L
Sbjct: 154 TSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWL 213
Query: 106 EVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFI 159
++ DG PLI +YCG K+P +RS+ + + F +D + GF A+Y +
Sbjct: 214 DIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
>gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens]
Length = 926
Score = 125 bits (315), Expect = 7e-29
Identities = 73/237 (30%), Positives = 121/237 (51%), Gaps = 24/237 (10%)
Query: 41 PATQCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAA-PRQRIELTFDEHYYIEPSFE 99
P CG + + + G+ SP YP YP ++ C +I+ A P Q+I L F+ H+ IE +
Sbjct: 24 PDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIE-KHD 82
Query: 100 CRFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFI 159
C++D +E+RDG + L+ ++CG +PP I S+G ++IKF+SD +G GF +Y
Sbjct: 83 CKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIF 142
Query: 160 PDPDFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKI 219
DC + +G + S + K +DC +TI A PK +I
Sbjct: 143 KTGS-----------EDCSKNFTSPNGTIESPGFPE----KYPHNLDCTFTILAKPKMEI 187
Query: 220 YLRFLDYQMEH------SNECKRNFVAVYDGSSSIENLKAKFCST-VANDVMLKTGI 269
L+FL + +EH +CK +++ ++DG + L K+C T +++ TGI
Sbjct: 188 ILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGI 244
Score = 69.3 bits (168), Expect = 8e-12
Identities = 38/114 (33%), Positives = 61/114 (53%), Gaps = 5/114 (4%)
Query: 51 TSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFD----EHYYIEPSF-ECRFDHL 105
TS G SP +P+ YP N +C + + A P+ I L F EH ++ +C++D L
Sbjct: 154 TSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWL 213
Query: 106 EVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFI 159
++ DG PLI +YCG K+P +RS+ + + F +D + GF A+Y +
Sbjct: 214 DIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
>gi|22547221 tolloid-like 1 [Homo sapiens]
Length = 1013
Score = 115 bits (289), Expect = 7e-26
Identities = 79/250 (31%), Positives = 119/250 (47%), Gaps = 23/250 (9%)
Query: 52 SNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGP 111
S G SPN+PD YP KEC + + A P RI+L F E + IE EC +DHLEV DG
Sbjct: 780 SPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSE-FEIEQHQECAYDHLEVFDGE 838
Query: 112 FGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGIL 171
SP++ R CG K P + +TG M+++F SD ++ GF+A +S T GG L
Sbjct: 839 TEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQATHS-------TECGGRL 891
Query: 172 NPIPDCQFELSGADGIVRS--SQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQME 229
A+ R S + + PGQ VDC W + + +++ L F +++E
Sbjct: 892 K-----------AESKPRDLYSHAQFGDNNYPGQ-VDCEWLLVSERGSRLELSFQTFEVE 939
Query: 230 HSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVMLKTGIGV-IRMWADEGSRLSRFRML 288
+C ++V ++DG S +FC + + + G V I D+ F +
Sbjct: 940 EEADCGYDYVELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKGFHIR 999
Query: 289 FTSFVEPPCT 298
+ S P T
Sbjct: 1000 YKSIRYPDTT 1009
Score = 112 bits (280), Expect = 8e-25
Identities = 79/249 (31%), Positives = 117/249 (46%), Gaps = 38/249 (15%)
Query: 45 CGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDH 104
CG +R N G SPNYPD Y P KEC++ + + + LTF + + IE C +D+
Sbjct: 462 CGGEIR-KNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTF-QSFEIERHDNCAYDY 519
Query: 105 LEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPD--- 161
LEVRDG SPLI R+CG P IRST +W+KF SD + GF A + D
Sbjct: 520 LEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKEEDECA 579
Query: 162 -PDFTYLGG----ILNPI--------------PD-------CQFELSGADGIVRSSQVEQ 195
PD GG LN + PD C L+ +G + + +
Sbjct: 580 KPD---RGGCEQRCLNTLGSYQCACEPGYELGPDRRSCEAACGGLLTKLNGTITTPGWPK 636
Query: 196 EEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKF 255
E +C+W + A + +I ++F +++E + CK ++V ++ G SS L KF
Sbjct: 637 EYPPNK----NCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVEIWSGLSSESKLHGKF 692
Query: 256 CSTVANDVM 264
C +V+
Sbjct: 693 CGAEVPEVI 701
Score = 105 bits (263), Expect = 8e-23
Identities = 63/212 (29%), Positives = 102/212 (48%), Gaps = 23/212 (10%)
Query: 45 CGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDH 104
CG ++ SNG + +SP +P+ YP CI+ + P ++I L F + S C +D+
Sbjct: 349 CGETLQESNG-NLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSL-CWYDY 406
Query: 105 LEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDF 164
+EVRDG + SPL+ R+CG K P ++ ST MWI+F S G GF A Y I
Sbjct: 407 IEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEAI----- 461
Query: 165 TYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFL 224
C E+ +G ++S + + +C+W I + + L F
Sbjct: 462 ------------CGGEIRKNEGQIQSPNYPDDYRPMK----ECVWKITVSESYHVGLTFQ 505
Query: 225 DYQMEHSNECKRNFVAVYDGSSSIENLKAKFC 256
+++E + C +++ V DG+S L +FC
Sbjct: 506 SFEIERHDNCAYDYLEVRDGTSENSPLIGRFC 537
Score = 96.3 bits (238), Expect = 6e-20
Identities = 64/240 (26%), Positives = 108/240 (45%), Gaps = 23/240 (9%)
Query: 51 TSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDG 110
T G +P +P YPPNK C++ + A + RI + F E + +E + C++D++E+ G
Sbjct: 623 TKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKF-EFFELEGNEVCKYDYVEIWSG 681
Query: 111 PFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGI 170
S L ++CG + P +I S M I+F SD + GF+A + D GG
Sbjct: 682 LSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKDNGGC 741
Query: 171 LNPIPD------CQ----FELSGADGIVRSSQVEQEEKTKPG------------QAVDCI 208
+ + CQ F L + ++ EQ+ + G +C
Sbjct: 742 QHECVNTMGSYMCQCRNGFVLHDNKHDCKEAECEQKIHSPSGLITSPNWPDKYPSRKECT 801
Query: 209 WTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVMLKTG 268
W I ATP +I L F ++++E EC + + V+DG + + + C D ++ TG
Sbjct: 802 WEISATPGHRIKLAFSEFEIEQHQECAYDHLEVFDGETEKSPILGRLCGNKIPDPLVATG 861
Score = 59.3 bits (142), Expect = 8e-09
Identities = 37/137 (27%), Positives = 70/137 (51%), Gaps = 4/137 (2%)
Query: 33 QNIGIKHIPATQCGIWVRTSNGGH--FASPNYPDS-YPPNKECIYILEAAPRQRIELTFD 89
Q G + +T+CG ++ + ++ + D+ YP +C ++L + R+EL+F
Sbjct: 875 QRKGFQATHSTECGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSF- 933
Query: 90 EHYYIEPSFECRFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEG 149
+ + +E +C +D++E+ DG + + R+CG P I S G + I F +D+ +
Sbjct: 934 QTFEVEEEADCGYDYVELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINK 993
Query: 150 LGFRAKYSFIPDPDFTY 166
GF +Y I PD T+
Sbjct: 994 KGFHIRYKSIRYPDTTH 1010
Score = 41.2 bits (95), Expect = 0.002
Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 3/91 (3%)
Query: 207 CIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVMLK 266
CIW + TP KI L F + S+ C +++ V DG L +FC +V+
Sbjct: 375 CIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIEVRDGYWRKSPLLGRFCGDKLPEVLTS 434
Query: 267 TGIGVIRMWADEGSRLSRFRMLFTSFVEPPC 297
T RMW + S + F + E C
Sbjct: 435 TD---SRMWIEFRSSSNWVGKGFAAVYEAIC 462
>gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo
sapiens]
Length = 986
Score = 115 bits (288), Expect = 1e-25
Identities = 72/242 (29%), Positives = 119/242 (49%), Gaps = 19/242 (7%)
Query: 51 TSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDG 110
TS G SPN+PD YP KEC + + + P R++LTF E IE EC +DHLEV DG
Sbjct: 752 TSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFME-MDIESQPECAYDHLEVFDG 810
Query: 111 PFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGI 170
+P++ R+CG K P + +TG M+++F SD ++ GF+A ++ T GG
Sbjct: 811 RDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHA-------TECGG- 862
Query: 171 LNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEH 230
+ ++ D S + + PG VDC W I A + L F +++E
Sbjct: 863 -----QVRADVKTKD---LYSHAQFGDNNYPG-GVDCEWVIVAEEGYGVELVFQTFEVEE 913
Query: 231 SNECKRNFVAVYDGSSSIENLKAKFCSTVANDVMLKTGIGV-IRMWADEGSRLSRFRMLF 289
+C +++ ++DG S ++C + + + G V ++ +D+ F + +
Sbjct: 914 ETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
Query: 290 TS 291
TS
Sbjct: 974 TS 975
Score = 112 bits (281), Expect = 6e-25
Identities = 94/325 (28%), Positives = 145/325 (44%), Gaps = 39/325 (12%)
Query: 55 GHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGF 114
GH SPNYPD Y P+K CI+ ++ + + LTF + + IE C +D+LEVRDG
Sbjct: 444 GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTF-QSFEIERHDSCAYDYLEVRDGHSES 502
Query: 115 SPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKY-SFIPDPDFTYLGGI--- 170
S LI RYCG + P I+ST +W+KF SD + GF + + + GG
Sbjct: 503 STLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQR 562
Query: 171 -LNPI--------------PD-------CQFELSGADGIVRSSQVEQEEKTKPGQAVDCI 208
LN + PD C L+ +G + S +E +CI
Sbjct: 563 CLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNK----NCI 618
Query: 209 WTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVMLKTG 268
W + A + +I L+F ++ E ++ CK +FV V G ++ L KFC + +V+
Sbjct: 619 WQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQY 678
Query: 269 IGV-IRMWADEGSRLSRFRMLFTSFVEPPCTSSTFFCHSNMCIN--NSLVCNGVQNCAYP 325
+ + +D F+ F S + C+ C + C+N S C
Sbjct: 679 NNMRVEFKSDNTVSKKGFKAHFFS-DKDECSKDNGGCQQD-CVNTFGSYECQCRSGFVLH 736
Query: 326 WDENHCKEKKKAGVFEQITKTHGTI 350
+++ CKE AG ++T T GTI
Sbjct: 737 DNKHDCKE---AGCDHKVTSTSGTI 758
Score = 100 bits (250), Expect = 2e-21
Identities = 70/269 (26%), Positives = 118/269 (43%), Gaps = 33/269 (12%)
Query: 45 CGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDH 104
CG ++ NG SP +P YPPNK CI+ L A + RI L FD + E + C++D
Sbjct: 591 CGGFLTKLNGS-ITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFD-FFETEGNDVCKYDF 648
Query: 105 LEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDF 164
+EVR G S L ++CG + P +I S M ++F SD + GF+A + D
Sbjct: 649 VEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECS 708
Query: 165 TYLGGILNPIPD--------------------------CQFELSGADGIVRSSQVEQEEK 198
GG + C +++ G + S +
Sbjct: 709 KDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYP 768
Query: 199 TKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCST 258
+K +C W I +TP ++ L F++ +E EC + + V+DG + + +FC +
Sbjct: 769 SKK----ECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGS 824
Query: 259 VANDVMLKTGIGV-IRMWADEGSRLSRFR 286
+ +L TG + +R ++D + F+
Sbjct: 825 KKPEPVLATGSRMFLRFYSDNSVQRKGFQ 853
Score = 95.5 bits (236), Expect = 1e-19
Identities = 101/423 (23%), Positives = 176/423 (41%), Gaps = 59/423 (13%)
Query: 45 CGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDH 104
CG ++ S G +F+SP YP+ Y + C++ + P ++I L F + S C +D+
Sbjct: 322 CGETLQDSTG-NFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTS-LDLYRSRLCWYDY 379
Query: 105 LEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDF 164
+EVRDG + +PL R+CG K P I ST +W++F S G GF A Y I
Sbjct: 380 VEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI----- 434
Query: 165 TYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFL 224
C ++ G ++S + +P + CIW I+ + + L F
Sbjct: 435 ------------CGGDVKKDYGHIQSPNYPDD--YRPSKV--CIWRIQVSEGFHVGLTFQ 478
Query: 225 DYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVMLKTGIGVIRMWADEGS-RLS 283
+++E + C +++ V DG S L ++C D + T + + +GS +
Sbjct: 479 SFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKA 538
Query: 284 RFRMLFTSFVEPPCTSSTFFCHSNMCIN--NSLVCNGVQNCAYPWDENHCKEKKKAGVFE 341
F + F V+ + C C+N S C+ D+ C + G F
Sbjct: 539 GFAVNFFKEVDECSRPNRGGCEQR-CLNTLGSYKCSCDPGYELAPDKRRC--EAACGGF- 594
Query: 342 QITKTHGTIIGITSGIVLVLLIISILVQVKQPRKKVMACKTAFNKTGFQEVFDPPHYELF 401
+TK +G+I P++ NK ++ P Y +
Sbjct: 595 -LTKLNGSI-----------------TSPGWPKEYPP------NKNCIWQLVAPTQYRI- 629
Query: 402 SLRDKEISADLADLSEELDNYQKMRRSSTASRCIHDHHCGSQASSVKQSRTNLSSMELPF 461
SL+ + D+ + ++ ++R TA +H CGS+ V S+ N +M + F
Sbjct: 630 SLQFDFFETEGNDVCKY--DFVEVRSGLTADSKLHGKFCGSEKPEVITSQYN--NMRVEF 685
Query: 462 RND 464
++D
Sbjct: 686 KSD 688
>gi|6912724 tolloid-like 2 [Homo sapiens]
Length = 1015
Score = 110 bits (275), Expect = 3e-24
Identities = 87/330 (26%), Positives = 141/330 (42%), Gaps = 45/330 (13%)
Query: 53 NGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPF 112
+ G SPNYPD Y P+KEC++ + + + LTF + + IE C +D+LEVRDGP
Sbjct: 471 DAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTF-QAFEIERHDSCAYDYLEVRDGPT 529
Query: 113 GFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRA------------------ 154
S LI +CG + P ++S+ +W+KF SD + GF A
Sbjct: 530 EESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPDHGGCE 589
Query: 155 --------KYSFIPDPDFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVD 206
Y DP + C ++ +G + S +E T +
Sbjct: 590 HRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNK----N 645
Query: 207 CIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVMLK 266
C+W + A + +I L+F +++E ++ CK +FV V G S L +FC + +V+
Sbjct: 646 CVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEVITS 705
Query: 267 TGIGV-IRMWADEGSRLSRFRMLFTSFVEPPCTSSTFFCHSNMCIN--NSLVC---NGVQ 320
+ + +D FR F S + C C + C+N S +C NG
Sbjct: 706 QSNNMRVEFKSDNTVSKRGFRAHFFS-DKDECAKDNGGC-QHECVNTFGSYLCRCRNGY- 762
Query: 321 NCAYPWDENHCKEKKKAGVFEQITKTHGTI 350
W + + K+AG +I+ GT+
Sbjct: 763 -----WLHENGHDCKEAGCAHKISSVEGTL 787
Score = 109 bits (273), Expect = 5e-24
Identities = 72/238 (30%), Positives = 115/238 (48%), Gaps = 19/238 (7%)
Query: 55 GHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGF 114
G ASPN+PD YP +EC + + + R++LTF+E + IE EC +DHLE+ DGP
Sbjct: 785 GTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNE-FEIEQHQECAYDHLEMYDGPDSL 843
Query: 115 SPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGILNPI 174
+P++ R+CG K P ++G M+++F SD ++ GF+A +S T GG L
Sbjct: 844 APILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHS-------TECGGRLKAE 896
Query: 175 PDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNEC 234
+ EL S + + P +A C W I A + L F +++E +C
Sbjct: 897 VQTK-EL--------YSHAQFGDNNYPSEA-RCDWVIVAEDGYGVELTFRTFEVEEEADC 946
Query: 235 KRNFVAVYDGSSSIENLKAKFCSTVANDVMLKTGIG-VIRMWADEGSRLSRFRMLFTS 291
+++ YDG S +FC + + + G +IR D+ F +TS
Sbjct: 947 GYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTS 1004
Score = 99.0 bits (245), Expect = 9e-21
Identities = 67/274 (24%), Positives = 124/274 (45%), Gaps = 33/274 (12%)
Query: 45 CGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDH 104
CG ++ NG SP +P YP NK C++ + A + RI L F E + +E + C++D
Sbjct: 620 CGGFITKLNGT-ITSPGWPKEYPTNKNCVWQVVAPAQYRISLQF-EVFELEGNDVCKYDF 677
Query: 105 LEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDF 164
+EVR G + L R+CG ++P +I S M ++F SD + GFRA + D
Sbjct: 678 VEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECA 737
Query: 165 TYLGGILNPIPD--------------------------CQFELSGADGIVRSSQVEQEEK 198
GG + + C ++S +G + S +
Sbjct: 738 KDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKYP 797
Query: 199 TKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCST 258
++ +C W I +T ++ L F ++++E EC + + +YDG S+ + +FC +
Sbjct: 798 SRR----ECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGS 853
Query: 259 VANDVMLKTGIGV-IRMWADEGSRLSRFRMLFTS 291
D + +G + +R ++D + F+ + ++
Sbjct: 854 KKPDPTVASGSSMFLRFYSDASVQRKGFQAVHST 887
Score = 92.0 bits (227), Expect = 1e-18
Identities = 92/413 (22%), Positives = 168/413 (40%), Gaps = 58/413 (14%)
Query: 55 GHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGF 114
G+F++P +P+ YP C++ + P ++I L F + C +D++EVRDG +
Sbjct: 360 GNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL-CWYDYVEVRDGYWRK 418
Query: 115 SPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGILNPI 174
+PL+ R+CG K P + ST +W++F S + G GF A Y
Sbjct: 419 APLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYE----------------- 461
Query: 175 PDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNEC 234
C +++ G ++S + + + +C+W I + + L F +++E + C
Sbjct: 462 ATCGGDMNKDAGQIQSPNYPDDYR----PSKECVWRITVSEGFHVGLTFQAFEIERHDSC 517
Query: 235 KRNFVAVYDGSSSIENLKAKFCS-TVANDVMLKTGIGVIRMWADEGSRLSRFRMLFTSFV 293
+++ V DG + L FC DV + ++ +D + F F V
Sbjct: 518 AYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEV 577
Query: 294 EPPCTSSTFFCHSNMCINNSLVCNGVQNCAYPWDENHCKEKKKAGVF--EQITKTHGTII 351
+ C+ + C+N G CA +KK V ITK +GTI
Sbjct: 578 D-ECSWPDHGGCEHRCVNTL----GSYKCACDPGYELAADKKMCEVACGGFITKLNGTI- 631
Query: 352 GITSGIVLVLLIISILVQVKQPRKKVMACKTAFNKTGFQEVFDPPHYELFSLRDKEISAD 411
P+ + NK +V P Y + SL+ + +
Sbjct: 632 ----------------TSPGWPK------EYPTNKNCVWQVVAPAQYRI-SLQFEVFELE 668
Query: 412 LADLSEELDNYQKMRRSSTASRCIHDHHCGSQASSVKQSRTNLSSMELPFRND 464
D+ + ++ ++R + +H CGS+ V S++N +M + F++D
Sbjct: 669 GNDVCKY--DFVEVRSGLSPDAKLHGRFCGSETPEVITSQSN--NMRVEFKSD 717
>gi|13899255 membrane frizzled-related protein [Homo sapiens]
Length = 579
Score = 107 bits (266), Expect = 3e-23
Identities = 91/331 (27%), Positives = 139/331 (41%), Gaps = 43/331 (12%)
Query: 33 QNIGIKHIPATQCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHY 92
Q G+ P + CG + + G F+SPNYPD YPPN C++ ++ A I+L E
Sbjct: 132 QESGVSPSPQSTCG-GLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKI-EAL 189
Query: 93 YIEPSFECRFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGF 152
IE C FD LE+ P G PL+ R CG PP + + + + F SD +EG GF
Sbjct: 190 SIESVASCLFDRLELSPEPEG--PLL-RVCGRVPPPTLNTNASHLLVVFVSDSSVEGFGF 246
Query: 153 RAKYS---------------------FIPDPDFTYLGGILN-----PIPDCQFELSGADG 186
A Y +PD + G N +C + SG G
Sbjct: 247 HAWYQAMAPGRGSCAHDEFRCDQLICLLPD---SVCDGFANCADGSDETNCSAKFSGCGG 303
Query: 187 IVRSSQ----VEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVY 242
+ Q + P Q + C W I I L+F ++ +E +ECK ++V VY
Sbjct: 304 NLTGLQGTFSTPSYLQQYPHQLL-CTWHISVPAGHSIELQFHNFSLEAQDECKFDYVEVY 362
Query: 243 DGSSS-IENLKAKFCSTVANDVMLKTGIGVIRMW-ADEGSRLSRFRMLFTSF--VEPPCT 298
+ SSS +L +FC ++ + + ++ D G F + +F E PC
Sbjct: 363 ETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATYLAFNATENPCG 422
Query: 299 SSTFFCHSNMCINNSLVCNGVQNCAYPWDEN 329
S C + C +C+ ++C D+N
Sbjct: 423 PSELSCQAGGCKGVQWMCDMWRDCTDGSDDN 453
Score = 58.9 bits (141), Expect = 1e-08
Identities = 42/146 (28%), Positives = 68/146 (46%), Gaps = 6/146 (4%)
Query: 12 VLLITVLVVEGIAVAQKTQDGQNIGIKHIPATQCGIWVRTSNGGHFASPNYPDSYPPNKE 71
+ L+ V +G A D N K + CG + T G F++P+Y YP
Sbjct: 271 ICLLPDSVCDGFANCADGSDETNCSAKF---SGCGGNL-TGLQGTFSTPSYLQQYPHQLL 326
Query: 72 CIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRD-GPFGFSPLIDRYCGVKSPPLI 130
C + + IEL F ++ +E EC+FD++EV + G L+ R+CG + PP +
Sbjct: 327 CTWHISVPAGHSIELQF-HNFSLEAQDECKFDYVEVYETSSSGAFSLLGRFCGAEPPPHL 385
Query: 131 RSTGRFMWIKFSSDEELEGLGFRAKY 156
S+ + + F +D + GF A Y
Sbjct: 386 VSSHHELAVLFRTDHGISSGGFSATY 411
Score = 33.5 bits (75), Expect = 0.49
Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 1/53 (1%)
Query: 297 CTSSTFFCHSNMCINNSLVCNGVQNCAYPWDENHCKEKKKAGVFEQITKTHGT 349
C F C +C+ VC+G NCA DE +C K +G +T GT
Sbjct: 260 CAHDEFRCDQLICLLPDSVCDGFANCADGSDETNC-SAKFSGCGGNLTGLQGT 311
>gi|66864913 neuropilin 1 isoform c [Homo sapiens]
Length = 609
Score = 101 bits (251), Expect = 2e-21
Identities = 58/220 (26%), Positives = 111/220 (50%), Gaps = 24/220 (10%)
Query: 44 QCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAA-PRQRIELTFDEHYYIEPSFECRF 102
+CG ++ + G+ SP YP SY P+++C ++++A P QRI + F+ H+ +E +C++
Sbjct: 26 KCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR-DCKY 84
Query: 103 DHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDP 162
D++EV DG ++CG +PP + S+G F++IKF SD E G GF +Y
Sbjct: 85 DYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYE----- 139
Query: 163 DFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLR 222
I P+C + G+++S + K +++C + + A ++I L
Sbjct: 140 -------IFKRGPECSQNYTTPSGVIKSPGFPE----KYPNSLECTYIVFAPKMSEIILE 188
Query: 223 FLDYQMEHSNE------CKRNFVAVYDGSSSIENLKAKFC 256
F + +E + C+ + + ++DG + ++C
Sbjct: 189 FESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYC 228
Score = 73.2 bits (178), Expect = 6e-13
Identities = 43/115 (37%), Positives = 59/115 (51%), Gaps = 7/115 (6%)
Query: 51 TSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFE------CRFDH 104
T+ G SP +P+ YP + EC YI+ A I L F E + +EP CR+D
Sbjct: 152 TTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEF-ESFDLEPDSNPPGGMFCRYDR 210
Query: 105 LEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFI 159
LE+ DG P I RYCG K+P IRS+ + + F +D + GF A YS +
Sbjct: 211 LEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVL 265
Score = 38.1 bits (87), Expect = 0.020
Identities = 18/63 (28%), Positives = 33/63 (52%), Gaps = 1/63 (1%)
Query: 207 CIWTIKAT-PKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVML 265
C W I+A P +I + F + +CK ++V V+DG + + + KFC +A ++
Sbjct: 54 CEWLIQAPDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVV 113
Query: 266 KTG 268
+G
Sbjct: 114 SSG 116
>gi|66912178 neuropilin 1 isoform b [Homo sapiens]
Length = 644
Score = 101 bits (251), Expect = 2e-21
Identities = 58/220 (26%), Positives = 111/220 (50%), Gaps = 24/220 (10%)
Query: 44 QCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAA-PRQRIELTFDEHYYIEPSFECRF 102
+CG ++ + G+ SP YP SY P+++C ++++A P QRI + F+ H+ +E +C++
Sbjct: 26 KCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR-DCKY 84
Query: 103 DHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDP 162
D++EV DG ++CG +PP + S+G F++IKF SD E G GF +Y
Sbjct: 85 DYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYE----- 139
Query: 163 DFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLR 222
I P+C + G+++S + K +++C + + A ++I L
Sbjct: 140 -------IFKRGPECSQNYTTPSGVIKSPGFPE----KYPNSLECTYIVFAPKMSEIILE 188
Query: 223 FLDYQMEHSNE------CKRNFVAVYDGSSSIENLKAKFC 256
F + +E + C+ + + ++DG + ++C
Sbjct: 189 FESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYC 228
Score = 73.2 bits (178), Expect = 6e-13
Identities = 43/115 (37%), Positives = 59/115 (51%), Gaps = 7/115 (6%)
Query: 51 TSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFE------CRFDH 104
T+ G SP +P+ YP + EC YI+ A I L F E + +EP CR+D
Sbjct: 152 TTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEF-ESFDLEPDSNPPGGMFCRYDR 210
Query: 105 LEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFI 159
LE+ DG P I RYCG K+P IRS+ + + F +D + GF A YS +
Sbjct: 211 LEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVL 265
Score = 38.1 bits (87), Expect = 0.020
Identities = 18/63 (28%), Positives = 33/63 (52%), Gaps = 1/63 (1%)
Query: 207 CIWTIKAT-PKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVML 265
C W I+A P +I + F + +CK ++V V+DG + + + KFC +A ++
Sbjct: 54 CEWLIQAPDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVV 113
Query: 266 KTG 268
+G
Sbjct: 114 SSG 116
>gi|182508169 neuropilin 1 isoform a [Homo sapiens]
Length = 923
Score = 101 bits (251), Expect = 2e-21
Identities = 58/220 (26%), Positives = 111/220 (50%), Gaps = 24/220 (10%)
Query: 44 QCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAA-PRQRIELTFDEHYYIEPSFECRF 102
+CG ++ + G+ SP YP SY P+++C ++++A P QRI + F+ H+ +E +C++
Sbjct: 26 KCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR-DCKY 84
Query: 103 DHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDP 162
D++EV DG ++CG +PP + S+G F++IKF SD E G GF +Y
Sbjct: 85 DYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYE----- 139
Query: 163 DFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLR 222
I P+C + G+++S + K +++C + + A ++I L
Sbjct: 140 -------IFKRGPECSQNYTTPSGVIKSPGFPE----KYPNSLECTYIVFAPKMSEIILE 188
Query: 223 FLDYQMEHSNE------CKRNFVAVYDGSSSIENLKAKFC 256
F + +E + C+ + + ++DG + ++C
Sbjct: 189 FESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYC 228
Score = 73.2 bits (178), Expect = 6e-13
Identities = 43/115 (37%), Positives = 59/115 (51%), Gaps = 7/115 (6%)
Query: 51 TSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFE------CRFDH 104
T+ G SP +P+ YP + EC YI+ A I L F E + +EP CR+D
Sbjct: 152 TTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEF-ESFDLEPDSNPPGGMFCRYDR 210
Query: 105 LEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFI 159
LE+ DG P I RYCG K+P IRS+ + + F +D + GF A YS +
Sbjct: 211 LEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVL 265
Score = 38.1 bits (87), Expect = 0.020
Identities = 18/63 (28%), Positives = 33/63 (52%), Gaps = 1/63 (1%)
Query: 207 CIWTIKAT-PKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVML 265
C W I+A P +I + F + +CK ++V V+DG + + + KFC +A ++
Sbjct: 54 CEWLIQAPDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVV 113
Query: 266 KTG 268
+G
Sbjct: 114 SSG 116
>gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo
sapiens]
Length = 730
Score = 95.5 bits (236), Expect = 1e-19
Identities = 101/423 (23%), Positives = 176/423 (41%), Gaps = 59/423 (13%)
Query: 45 CGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDH 104
CG ++ S G +F+SP YP+ Y + C++ + P ++I L F + S C +D+
Sbjct: 322 CGETLQDSTG-NFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTS-LDLYRSRLCWYDY 379
Query: 105 LEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDF 164
+EVRDG + +PL R+CG K P I ST +W++F S G GF A Y I
Sbjct: 380 VEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI----- 434
Query: 165 TYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFL 224
C ++ G ++S + +P + CIW I+ + + L F
Sbjct: 435 ------------CGGDVKKDYGHIQSPNYPDD--YRPSKV--CIWRIQVSEGFHVGLTFQ 478
Query: 225 DYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVMLKTGIGVIRMWADEGS-RLS 283
+++E + C +++ V DG S L ++C D + T + + +GS +
Sbjct: 479 SFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKA 538
Query: 284 RFRMLFTSFVEPPCTSSTFFCHSNMCIN--NSLVCNGVQNCAYPWDENHCKEKKKAGVFE 341
F + F V+ + C C+N S C+ D+ C + G F
Sbjct: 539 GFAVNFFKEVDECSRPNRGGCEQR-CLNTLGSYKCSCDPGYELAPDKRRC--EAACGGF- 594
Query: 342 QITKTHGTIIGITSGIVLVLLIISILVQVKQPRKKVMACKTAFNKTGFQEVFDPPHYELF 401
+TK +G+I P++ NK ++ P Y +
Sbjct: 595 -LTKLNGSI-----------------TSPGWPKEYPP------NKNCIWQLVAPTQYRI- 629
Query: 402 SLRDKEISADLADLSEELDNYQKMRRSSTASRCIHDHHCGSQASSVKQSRTNLSSMELPF 461
SL+ + D+ + ++ ++R TA +H CGS+ V S+ N +M + F
Sbjct: 630 SLQFDFFETEGNDVCKY--DFVEVRSGLTADSKLHGKFCGSEKPEVITSQYN--NMRVEF 685
Query: 462 RND 464
++D
Sbjct: 686 KSD 688
Score = 75.9 bits (185), Expect = 9e-14
Identities = 42/112 (37%), Positives = 61/112 (54%), Gaps = 2/112 (1%)
Query: 45 CGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDH 104
CG ++ NG SP +P YPPNK CI+ L A + RI L FD + E + C++D
Sbjct: 591 CGGFLTKLNGS-ITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFD-FFETEGNDVCKYDF 648
Query: 105 LEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKY 156
+EVR G S L ++CG + P +I S M ++F SD + GF+A +
Sbjct: 649 VEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
>gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo
sapiens]
Length = 823
Score = 95.5 bits (236), Expect = 1e-19
Identities = 101/423 (23%), Positives = 176/423 (41%), Gaps = 59/423 (13%)
Query: 45 CGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDH 104
CG ++ S G +F+SP YP+ Y + C++ + P ++I L F + S C +D+
Sbjct: 322 CGETLQDSTG-NFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTS-LDLYRSRLCWYDY 379
Query: 105 LEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDF 164
+EVRDG + +PL R+CG K P I ST +W++F S G GF A Y I
Sbjct: 380 VEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI----- 434
Query: 165 TYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFL 224
C ++ G ++S + +P + CIW I+ + + L F
Sbjct: 435 ------------CGGDVKKDYGHIQSPNYPDD--YRPSKV--CIWRIQVSEGFHVGLTFQ 478
Query: 225 DYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVMLKTGIGVIRMWADEGS-RLS 283
+++E + C +++ V DG S L ++C D + T + + +GS +
Sbjct: 479 SFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKA 538
Query: 284 RFRMLFTSFVEPPCTSSTFFCHSNMCIN--NSLVCNGVQNCAYPWDENHCKEKKKAGVFE 341
F + F V+ + C C+N S C+ D+ C + G F
Sbjct: 539 GFAVNFFKEVDECSRPNRGGCEQR-CLNTLGSYKCSCDPGYELAPDKRRC--EAACGGF- 594
Query: 342 QITKTHGTIIGITSGIVLVLLIISILVQVKQPRKKVMACKTAFNKTGFQEVFDPPHYELF 401
+TK +G+I P++ NK ++ P Y +
Sbjct: 595 -LTKLNGSI-----------------TSPGWPKEYPP------NKNCIWQLVAPTQYRI- 629
Query: 402 SLRDKEISADLADLSEELDNYQKMRRSSTASRCIHDHHCGSQASSVKQSRTNLSSMELPF 461
SL+ + D+ + ++ ++R TA +H CGS+ V S+ N +M + F
Sbjct: 630 SLQFDFFETEGNDVCKY--DFVEVRSGLTADSKLHGKFCGSEKPEVITSQYN--NMRVEF 685
Query: 462 RND 464
++D
Sbjct: 686 KSD 688
Score = 75.9 bits (185), Expect = 9e-14
Identities = 42/112 (37%), Positives = 61/112 (54%), Gaps = 2/112 (1%)
Query: 45 CGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDH 104
CG ++ NG SP +P YPPNK CI+ L A + RI L FD + E + C++D
Sbjct: 591 CGGFLTKLNGS-ITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFD-FFETEGNDVCKYDF 648
Query: 105 LEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKY 156
+EVR G S L ++CG + P +I S M ++F SD + GF+A +
Sbjct: 649 VEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
>gi|72384339 CUB domain containing protein 2 [Homo sapiens]
Length = 449
Score = 92.4 bits (228), Expect = 9e-19
Identities = 65/217 (29%), Positives = 104/217 (47%), Gaps = 29/217 (13%)
Query: 32 GQNIGIKHIPATQCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEH 91
G + + + +CG V ++ G+F+SPN+P YP N EC +++ A + LTF
Sbjct: 17 GPGLQAQAMEGVKCG-GVLSAPSGNFSSPNFPRLYPYNTECSWLIVVAEGSSVLLTFHA- 74
Query: 92 YYIEPSFECRFDHLEVRDGPFGFSP----LIDRYCGVKSPPLIRSTGRFMWIKFSSDEEL 147
+ +E C FD LE+ +G SP L+ R+CG PP S+ M + F SD+ +
Sbjct: 75 FDLEYHDTCSFDFLEIYNGA---SPDKGNLLGRFCGKVPPPPFTSSWHVMSVIFHSDKHV 131
Query: 148 EGLGFRAKYSFIPDPDFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDC 207
GF A Y GG+L +G G++ S + +++C
Sbjct: 132 ASHGFSAGYQK------DVCGGVL----------TGLSGVLTSPEYPNNYPN----SMEC 171
Query: 208 IWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDG 244
W I+A A + L F+D+Q+E + EC ++VAV G
Sbjct: 172 HWVIRAAGPAHVKLVFVDFQVEGNEECTYDYVAVLGG 208
Score = 84.7 bits (208), Expect = 2e-16
Identities = 62/216 (28%), Positives = 95/216 (43%), Gaps = 28/216 (12%)
Query: 45 CGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDH 104
CG V T G SP YP++YP + EC +++ AA ++L F + + +E + EC +D+
Sbjct: 145 CG-GVLTGLSGVLTSPEYPNNYPNSMECHWVIRAAGPAHVKLVFVD-FQVEGNEECTYDY 202
Query: 105 LEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDF 164
+ V GP YCG PP + S G + + F SD + G GF+A Y
Sbjct: 203 VAVLGGPGPTRG--HHYCGSTRPPTLVSLGHELQVVFKSDFNIGGRGFKAYY-------- 252
Query: 165 TYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFL 224
+ G +CQ G S Q + C WTI+ P ++ + FL
Sbjct: 253 -FSG-------ECQEVYMAMRGNFSSPQYPSSYPNN----IRCHWTIRLPPGYQVKVFFL 300
Query: 225 DYQMEHSNE----CKRNFVAVYDGSSSIENLKAKFC 256
D +E N C + +A +DG+S L +C
Sbjct: 301 DLDLEEPNSLTKTCDFDHLAAFDGASEEAPLLGNWC 336
Score = 61.6 bits (148), Expect = 2e-09
Identities = 33/105 (31%), Positives = 51/105 (48%), Gaps = 3/105 (2%)
Query: 55 GHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSF---ECRFDHLEVRDGP 111
G+F+SP YP SYP N C + + P ++++ F + EP+ C FDHL DG
Sbjct: 266 GNFSSPQYPSSYPNNIRCHWTIRLPPGYQVKVFFLDLDLEEPNSLTKTCDFDHLAAFDGA 325
Query: 112 FGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKY 156
+PL+ +CG PP + S+ + + +D GF Y
Sbjct: 326 SEEAPLLGNWCGHHLPPPVTSSHNQLLLLLHTDRSTTRRGFSVAY 370
Score = 37.0 bits (84), Expect = 0.044
Identities = 16/55 (29%), Positives = 30/55 (54%), Gaps = 1/55 (1%)
Query: 206 DCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIE-NLKAKFCSTV 259
+C W I + + L F + +E+ + C +F+ +Y+G+S + NL +FC V
Sbjct: 55 ECSWLIVVAEGSSVLLTFHAFDLEYHDTCSFDFLEIYNGASPDKGNLLGRFCGKV 109
>gi|157653329 procollagen C-endopeptidase enhancer [Homo sapiens]
Length = 449
Score = 83.2 bits (204), Expect = 5e-16
Identities = 64/219 (29%), Positives = 100/219 (45%), Gaps = 18/219 (8%)
Query: 41 PATQCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFEC 100
P CG V+ G+ AS +P+ YPPNKECI+ + Q + L+F + +E C
Sbjct: 33 PVFLCGGDVK-GESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSF-RVFDLELHPAC 90
Query: 101 RFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYS--F 158
R+D LEV G + R+CG P + + G + ++ ++DE G GF YS
Sbjct: 91 RYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWYSGRA 150
Query: 159 IPDPDFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAK 218
+ + GG L A G + + E PG + C W I A P
Sbjct: 151 TSGTEHQFCGG----------RLEKAQGTLTTPN-WPESDYPPG--ISCSWHIIAPPDQV 197
Query: 219 IYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLK-AKFC 256
I L F + +E C+ + V+V++G+ S ++ + KFC
Sbjct: 198 IALTFEKFDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFC 236
Score = 64.3 bits (155), Expect = 3e-10
Identities = 39/108 (36%), Positives = 57/108 (52%), Gaps = 3/108 (2%)
Query: 55 GHFASPNYPDS-YPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFG 113
G +PN+P+S YPP C + + A P Q I LTF E + +EP CR+D + V +G
Sbjct: 168 GTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTF-EKFDLEPDTYCRYDSVSVFNGAVS 226
Query: 114 F-SPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIP 160
S + ++CG P I S G + ++F SD + GF A Y +P
Sbjct: 227 DDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKTLP 274
Score = 38.5 bits (88), Expect = 0.015
Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
Query: 206 DCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVML 265
+CIWTI + L F + +E C+ + + V+ GS + +FC T ++
Sbjct: 62 ECIWTITVPEGQTVSLSFRVFDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPLV 121
Query: 266 KTGIGV-IRMWADEGS 280
G V +RM DEG+
Sbjct: 122 APGNQVTLRMTTDEGT 137
>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
Length = 3565
Score = 81.3 bits (199), Expect = 2e-15
Identities = 46/132 (34%), Positives = 68/132 (51%), Gaps = 8/132 (6%)
Query: 30 QDGQNIGIKHIPATQ--CGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELT 87
QDG + +P + CG + T++ G P +P Y + C +I+EA P I++T
Sbjct: 742 QDGNVVWSSTVPRCEAPCGGHL-TASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKIT 800
Query: 88 FDEHYYIEPSFECRFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEEL 147
FD E +D LEVRDGP SPLI Y G ++P + STG FM++ F++D
Sbjct: 801 FDRF-----QTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSR 855
Query: 148 EGLGFRAKYSFI 159
+GF Y +
Sbjct: 856 SSIGFLIHYESV 867
Score = 67.8 bits (164), Expect = 2e-11
Identities = 69/277 (24%), Positives = 115/277 (41%), Gaps = 53/277 (19%)
Query: 51 TSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDG 110
T++ G SPNYP+ Y N C++++ + P RI L F++ + +EP +FD L V+D
Sbjct: 590 TASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFND-FDVEP----QFDFLAVKDD 644
Query: 111 PFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFI-----PDP--- 162
++ + G + P + S+G + ++F SD G GF Y+ DP
Sbjct: 645 GISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDPGIP 704
Query: 163 -------DFTYLGGILNPIPDCQF-ELSGADGI---------VRSSQVEQEEKTKPG--- 202
D LG ++ D F + G++ I V SS V + E G
Sbjct: 705 INGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLT 764
Query: 203 ----------------QAVDCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSS 246
++ C W I+A P I + F +Q E + + V DG +
Sbjct: 765 ASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQ----TEVNYDTLEVRDGPA 820
Query: 247 SIENLKAKFCSTVANDVMLKTGIGVIRMWADEGSRLS 283
S L ++ T A ++ TG + ++ + SR S
Sbjct: 821 SSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSS 857
Score = 67.4 bits (163), Expect = 3e-11
Identities = 70/291 (24%), Positives = 109/291 (37%), Gaps = 61/291 (20%)
Query: 54 GGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHY-YIEPSFECRFDHLEVRDGPF 112
GG SP +P SYP N +C + R + + + H ++ S E D LE+++GP+
Sbjct: 1983 GGVILSPGFPGSYPNNLDCTW------RISLPIGYGAHIQFLNFSTEANHDFLEIQNGPY 2036
Query: 113 GFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSF-----IPDP----- 162
SP+I ++ G P + ST I F SD GF+ Y PDP
Sbjct: 2037 HTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDPPPFQN 2096
Query: 163 ------DFT---------YLGGIL--NPIPDCQ-------------------FELSGADG 186
D++ Y G IL +P+ CQ + ++ +G
Sbjct: 2097 GYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPCGYNVTSQNG 2156
Query: 187 IVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSS 246
+ S E DCIW I P +Y+ F Q E N+ ++AV+DG
Sbjct: 2157 TIYSPGFPDEYPI----LKDCIWLITVPPGHGVYINFTLLQTEAVND----YIAVWDGPD 2208
Query: 247 SIENLKAKFCSTVANDVMLKTGIGVIRMWADEGSRLSRFRMLFTSFVEPPC 297
F A + + V+ + + S F + F +F C
Sbjct: 2209 QNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKKC 2259
Score = 66.6 bits (161), Expect = 5e-11
Identities = 74/302 (24%), Positives = 112/302 (37%), Gaps = 61/302 (20%)
Query: 44 QCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFD 103
+CG + + G SP YP Y N C +I+EA P + I L ++I E D
Sbjct: 1277 ECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISL-----HFIVFDTEMAHD 1331
Query: 104 HLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYS------ 157
L+V DGP L+ + G P I ST + ++F SD + GF ++S
Sbjct: 1332 ILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAAT 1391
Query: 158 ------------------------FIPDPDFTYLGGI------LNP-----------IPD 176
F DP + G LN I
Sbjct: 1392 CNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAA 1451
Query: 177 CQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNECKR 236
C L+G G++ S Q PG+ +C W +K P I L F + ME S +
Sbjct: 1452 CGGNLTGPAGVILSPNYPQ--PYPPGK--ECDWRVKVNPDFVIALIFKSFNMEPSYD--- 1504
Query: 237 NFVAVYDGSSSIENLKAKFCSTVANDVMLKTGIGVIRMWADEGS-RLSRFRMLFTSFVEP 295
F+ +Y+G S L + + A + + +G + + + S LS F + F
Sbjct: 1505 -FLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPRE 1563
Query: 296 PC 297
C
Sbjct: 1564 AC 1565
Score = 66.2 bits (160), Expect = 7e-11
Identities = 42/122 (34%), Positives = 61/122 (50%), Gaps = 5/122 (4%)
Query: 51 TSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDG 110
T G SPNYP YPP KEC + ++ P I L F + + +EPS+ D L + +G
Sbjct: 1457 TGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIF-KSFNMEPSY----DFLHIYEG 1511
Query: 111 PFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGI 170
SPLI Y G ++P I S+G +++ F SD + GF ++ P G I
Sbjct: 1512 EDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFDPGNI 1571
Query: 171 LN 172
+N
Sbjct: 1572 MN 1573
Score = 64.7 bits (156), Expect = 2e-10
Identities = 75/278 (26%), Positives = 101/278 (36%), Gaps = 74/278 (26%)
Query: 2 ALERLCSVLKVLLITVLVVEGIAVAQKTQDGQNIGIKHIPATQCGIWVRTSNGGHFASPN 61
A R S+L +L + VL + A+ GQN CG V+ NG SP
Sbjct: 3 AWRRFQSLLLLLGLLVLCARLLTAAK----GQN----------CGGLVQGPNGT-IESPG 47
Query: 62 YPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGFSPLIDRY 121
+P YP C +I+ R RI+L+F H + + E FD L V DG L R
Sbjct: 48 FPHGYPNYANCTWIIITGERNRIQLSF--HTF---ALEEDFDILSVYDGQPQQGNLKVRL 102
Query: 122 CGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGILN--------- 172
G + P I STG + + F++D + GF+A Y +P G IL
Sbjct: 103 SGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGNPGEILKGVLHGTRFN 162
Query: 173 -----------------------------------PIPDCQFE------LSGADGIVRSS 191
P P C+ E L G + S
Sbjct: 163 IGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRAEGACGGTLRGTSSSISSP 222
Query: 192 QVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQME 229
E + DC WTI A P I L F D+Q+E
Sbjct: 223 HFPSEYENN----ADCTWTILAEPGDTIALVFTDFQLE 256
Score = 62.8 bits (151), Expect = 8e-10
Identities = 73/304 (24%), Positives = 120/304 (39%), Gaps = 62/304 (20%)
Query: 42 ATQCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAA-PRQRIELTFDEHYYIEPSFEC 100
A CG +R +G SPNYP Y N C++++ P + I+L F+E E
Sbjct: 409 ARTCGSNLRGPSGV-ITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEF-----ELER 462
Query: 101 RFDHLEVRD-GPFGFS-PLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKY-- 156
+D L V D G G + ++ G P LI S MW+ SD+ + GF+A Y
Sbjct: 463 GYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQE 522
Query: 157 --------------------SFIPDPDFTY----------------------LGGILNPI 174
SF+ T+ G + +
Sbjct: 523 IEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCV 582
Query: 175 PDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNEC 234
C F + + GI+ S +E G ++C+W I + P ++I+L F D+ +E
Sbjct: 583 FSCFFNFTASSGIILSPNYPEEY----GNNMNCVWLIISEPGSRIHLIFNDFDVEP---- 634
Query: 235 KRNFVAVY-DGSSSIENLKAKFCSTVANDVMLKTGIGVIRMWADEGSRLSRFRMLFTSFV 293
+ +F+AV DG S I L + V + + I + +D + F + +T+F
Sbjct: 635 QFDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFG 694
Query: 294 EPPC 297
+ C
Sbjct: 695 QNEC 698
Score = 55.5 bits (132), Expect = 1e-07
Identities = 68/325 (20%), Positives = 114/325 (35%), Gaps = 66/325 (20%)
Query: 51 TSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDG 110
T G SP YP+ Y N CI+ + I++ I + E +D LE+ DG
Sbjct: 1808 TQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQV-----ISFATEQNWDSLEIHDG 1862
Query: 111 PFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKY-------------- 156
+P + + G P L+ ST +++ F SD + GF +Y
Sbjct: 1863 GDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQEPALP 1922
Query: 157 ----------------SFIPDPDFTYLG--------GILNP--------IPDCQFELSGA 184
SF +P +T G G + I C LS
Sbjct: 1923 SNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIATCGGTLSTL 1982
Query: 185 DGIVRSSQVEQEEKTKPG---QAVDCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAV 241
G++ S PG +DC W I +++FL++ S E +F+ +
Sbjct: 1983 GGVILSPGF-------PGSYPNNLDCTWRISLPIGYGAHIQFLNF----STEANHDFLEI 2031
Query: 242 YDGSSSIENLKAKFCSTVANDVMLK-TGIGVIRMWADEGSRLSRFRMLFTSFVEPPCTSS 300
+G + +F T +L T +I ++D F++ + ++ C
Sbjct: 2032 QNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDP 2091
Query: 301 TFFCHSNMCINNSLVCNGVQNCAYP 325
F + M ++ V V YP
Sbjct: 2092 PPFQNGYMINSDYSVGQSVSFECYP 2116
Score = 50.1 bits (118), Expect = 5e-06
Identities = 39/128 (30%), Positives = 60/128 (46%), Gaps = 10/128 (7%)
Query: 49 VRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVR 108
VRT + G SP YP +Y ++ C + ++ P I + D E +FD LEV
Sbjct: 2325 VRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTF-----QSEKQFDALEVF 2379
Query: 109 DGPFGFSPLIDRYCGVKSPPL-IRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTY- 166
DG G SPL+ G + S +++++S+D GF+ +Y+ P T+
Sbjct: 2380 DGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYA-APYCSLTHP 2438
Query: 167 --LGGILN 172
GGILN
Sbjct: 2439 LKNGGILN 2446
Score = 47.8 bits (112), Expect = 3e-05
Identities = 56/246 (22%), Positives = 87/246 (35%), Gaps = 56/246 (22%)
Query: 44 QCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFD 103
+CG V+ N G SPN+P +Y N ECIY +E + I L E D
Sbjct: 1104 ECGASVK-GNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEG------D 1156
Query: 104 HLEVRDGPFGFSPLIDRYCGVKSPPLI-RSTGRFMWIKFSSDEELEGLGFRAKYSFI--- 159
L+V DG S + + + LI ST +W++F+++ GF+ Y+
Sbjct: 1157 TLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLV 1216
Query: 160 --PDPDFTYLGGIL--------------------------------------NPIPDCQF 179
DP G + P+P C
Sbjct: 1217 KCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIA 1276
Query: 180 ELSGADGIVRSSQVEQEEKTKP-GQAVDCIWTIKATPKAKIYLRFLDYQMEHSNECKRNF 238
E G S ++ P + C W I+A P I L F+ + E +++
Sbjct: 1277 ECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHD----I 1332
Query: 239 VAVYDG 244
+ V+DG
Sbjct: 1333 LKVWDG 1338
Score = 44.7 bits (104), Expect = 2e-04
Identities = 31/100 (31%), Positives = 46/100 (46%), Gaps = 6/100 (6%)
Query: 45 CGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDH 104
CG V TS G SP +PD YP K+CI+++ P + + F E D+
Sbjct: 2147 CGYNV-TSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINF-----TLLQTEAVNDY 2200
Query: 105 LEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSD 144
+ V DGP SP + + G + S+ + +KF SD
Sbjct: 2201 IAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSD 2240
Score = 37.7 bits (86), Expect = 0.026
Identities = 30/124 (24%), Positives = 51/124 (41%), Gaps = 7/124 (5%)
Query: 51 TSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDG 110
T + G SPNYP +Y + C+Y + P++ + F + Y + + D E+ DG
Sbjct: 1631 TGSEGVVLSPNYPHNYTAGQICLYSI-TVPKEFV--VFGQFAYFQTALN---DLAELFDG 1684
Query: 111 PFGFSPLIDRYCGVKS-PPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGG 169
+ L+ G S L +T + ++FS+ GF Y +P T
Sbjct: 1685 THAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSDTQCSS 1744
Query: 170 ILNP 173
+ P
Sbjct: 1745 VPEP 1748
Score = 37.0 bits (84), Expect = 0.044
Identities = 28/112 (25%), Positives = 49/112 (43%), Gaps = 10/112 (8%)
Query: 45 CGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDH 104
CG +R ++ +SP++P Y N +C + + A P I L F + E +D
Sbjct: 208 CGGTLRGTSSS-ISSPHFPSEYENNADCTWTILAEPGDTIALVFTDF-----QLEEGYDF 261
Query: 105 LEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKY 156
LE+ G G+ P + S+ ++ + F+SD GF A++
Sbjct: 262 LEIS----GTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQF 309
Score = 36.2 bits (82), Expect = 0.075
Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 10/116 (8%)
Query: 45 CGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDH 104
CG +++ G SP +PD YP + C + +E + + +++ F +++E S +
Sbjct: 931 CGGYIQ-GKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIF-HTFHLESSHDYL--- 985
Query: 105 LEVRDGPFGFSPLIDRYCGVKSPPLIRS--TGRF-MWIKFSSDEELEGLGFRAKYS 157
L DG FS + R G P I++ G F ++F SD + GF +S
Sbjct: 986 LITEDG--SFSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFS 1039
>gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]
Length = 1662
Score = 77.0 bits (188), Expect = 4e-14
Identities = 43/114 (37%), Positives = 63/114 (55%), Gaps = 6/114 (5%)
Query: 55 GHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGF 114
G F+SP YP +YP N +C++ +E R+ + F + ++ C +D++EV DGP+
Sbjct: 1266 GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRD---VQLEGGCNYDYIEVFDGPYRS 1322
Query: 115 SPLIDRYC-GVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYL 167
SPLI R C G + S+ FM I+F SD + GFRA+Y P D T L
Sbjct: 1323 SPLIARVCDGARGS--FTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDSTNL 1374
Score = 65.5 bits (158), Expect = 1e-10
Identities = 39/120 (32%), Positives = 63/120 (52%), Gaps = 3/120 (2%)
Query: 41 PATQCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFEC 100
P++ CG ++ ++G F+SP+YP YP N +C++ +E RI L F + +E C
Sbjct: 1011 PSSNCGGFLFYASGT-FSSPSYPAYYPNNAKCVWEIEVNSGYRINLGF-SNLKLEAHHNC 1068
Query: 101 RFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIP 160
FD++E+ DG S L+ + C + + S+ M I F SD + GF A Y+ P
Sbjct: 1069 SFDYVEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFP 1127
Score = 37.0 bits (84), Expect = 0.044
Identities = 15/51 (29%), Positives = 28/51 (54%)
Query: 207 CIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCS 257
C+W I+ +I L F + ++E + C ++V ++DGS + L K C+
Sbjct: 1041 CVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICN 1091
Score = 35.0 bits (79), Expect = 0.17
Identities = 24/101 (23%), Positives = 39/101 (38%), Gaps = 4/101 (3%)
Query: 207 CIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVMLK 266
C+W I+ ++ + F D Q+E C +++ V+DG L A+ C
Sbjct: 1283 CVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSS 1340
Query: 267 TGIGVIRMWADEGSRLSRFRMLFTSFVEPPCTSSTFFCHSN 307
+ IR +D FR + S P S+ C N
Sbjct: 1341 SNFMSIRFISDHSITRRGFRAEYYS--SPSNDSTNLLCLPN 1379
>gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]
Length = 1788
Score = 77.0 bits (188), Expect = 4e-14
Identities = 43/114 (37%), Positives = 63/114 (55%), Gaps = 6/114 (5%)
Query: 55 GHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGF 114
G F+SP YP +YP N +C++ +E R+ + F + ++ C +D++EV DGP+
Sbjct: 1392 GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRD---VQLEGGCNYDYIEVFDGPYRS 1448
Query: 115 SPLIDRYC-GVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYL 167
SPLI R C G + S+ FM I+F SD + GFRA+Y P D T L
Sbjct: 1449 SPLIARVCDGARGS--FTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDSTNL 1500
Score = 65.5 bits (158), Expect = 1e-10
Identities = 39/120 (32%), Positives = 63/120 (52%), Gaps = 3/120 (2%)
Query: 41 PATQCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFEC 100
P++ CG ++ ++G F+SP+YP YP N +C++ +E RI L F + +E C
Sbjct: 1137 PSSNCGGFLFYASGT-FSSPSYPAYYPNNAKCVWEIEVNSGYRINLGF-SNLKLEAHHNC 1194
Query: 101 RFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIP 160
FD++E+ DG S L+ + C + + S+ M I F SD + GF A Y+ P
Sbjct: 1195 SFDYVEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFP 1253
Score = 37.0 bits (84), Expect = 0.044
Identities = 15/51 (29%), Positives = 28/51 (54%)
Query: 207 CIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCS 257
C+W I+ +I L F + ++E + C ++V ++DGS + L K C+
Sbjct: 1167 CVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICN 1217
Score = 35.0 bits (79), Expect = 0.17
Identities = 24/101 (23%), Positives = 39/101 (38%), Gaps = 4/101 (3%)
Query: 207 CIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVMLK 266
C+W I+ ++ + F D Q+E C +++ V+DG L A+ C
Sbjct: 1409 CVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSS 1466
Query: 267 TGIGVIRMWADEGSRLSRFRMLFTSFVEPPCTSSTFFCHSN 307
+ IR +D FR + S P S+ C N
Sbjct: 1467 SNFMSIRFISDHSITRRGFRAEYYS--SPSNDSTNLLCLPN 1505
>gi|148539844 deleted in malignant brain tumors 1 isoform c precursor
[Homo sapiens]
Length = 2403
Score = 77.0 bits (188), Expect = 4e-14
Identities = 43/114 (37%), Positives = 63/114 (55%), Gaps = 6/114 (5%)
Query: 55 GHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGF 114
G F+SP YP +YP N +C++ +E R+ + F + ++ C +D++EV DGP+
Sbjct: 2007 GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRD---VQLEGGCNYDYIEVFDGPYRS 2063
Query: 115 SPLIDRYC-GVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYL 167
SPLI R C G + S+ FM I+F SD + GFRA+Y P D T L
Sbjct: 2064 SPLIARVCDGARGS--FTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDSTNL 2115
Score = 65.5 bits (158), Expect = 1e-10
Identities = 39/120 (32%), Positives = 63/120 (52%), Gaps = 3/120 (2%)
Query: 41 PATQCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFEC 100
P++ CG ++ ++G F+SP+YP YP N +C++ +E RI L F + +E C
Sbjct: 1752 PSSNCGGFLFYASGT-FSSPSYPAYYPNNAKCVWEIEVNSGYRINLGF-SNLKLEAHHNC 1809
Query: 101 RFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIP 160
FD++E+ DG S L+ + C + + S+ M I F SD + GF A Y+ P
Sbjct: 1810 SFDYVEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFP 1868
Score = 37.0 bits (84), Expect = 0.044
Identities = 15/51 (29%), Positives = 28/51 (54%)
Query: 207 CIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCS 257
C+W I+ +I L F + ++E + C ++V ++DGS + L K C+
Sbjct: 1782 CVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICN 1832
Score = 35.0 bits (79), Expect = 0.17
Identities = 24/101 (23%), Positives = 39/101 (38%), Gaps = 4/101 (3%)
Query: 207 CIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVMLK 266
C+W I+ ++ + F D Q+E C +++ V+DG L A+ C
Sbjct: 2024 CVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSS 2081
Query: 267 TGIGVIRMWADEGSRLSRFRMLFTSFVEPPCTSSTFFCHSN 307
+ IR +D FR + S P S+ C N
Sbjct: 2082 SNFMSIRFISDHSITRRGFRAEYYS--SPSNDSTNLLCLPN 2120
>gi|148539842 deleted in malignant brain tumors 1 isoform b precursor
[Homo sapiens]
Length = 2413
Score = 77.0 bits (188), Expect = 4e-14
Identities = 43/114 (37%), Positives = 63/114 (55%), Gaps = 6/114 (5%)
Query: 55 GHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGF 114
G F+SP YP +YP N +C++ +E R+ + F + ++ C +D++EV DGP+
Sbjct: 2017 GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRD---VQLEGGCNYDYIEVFDGPYRS 2073
Query: 115 SPLIDRYC-GVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYL 167
SPLI R C G + S+ FM I+F SD + GFRA+Y P D T L
Sbjct: 2074 SPLIARVCDGARGS--FTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDSTNL 2125
Score = 65.5 bits (158), Expect = 1e-10
Identities = 39/120 (32%), Positives = 63/120 (52%), Gaps = 3/120 (2%)
Query: 41 PATQCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFEC 100
P++ CG ++ ++G F+SP+YP YP N +C++ +E RI L F + +E C
Sbjct: 1762 PSSNCGGFLFYASGT-FSSPSYPAYYPNNAKCVWEIEVNSGYRINLGF-SNLKLEAHHNC 1819
Query: 101 RFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIP 160
FD++E+ DG S L+ + C + + S+ M I F SD + GF A Y+ P
Sbjct: 1820 SFDYVEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFP 1878
Score = 37.0 bits (84), Expect = 0.044
Identities = 15/51 (29%), Positives = 28/51 (54%)
Query: 207 CIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCS 257
C+W I+ +I L F + ++E + C ++V ++DGS + L K C+
Sbjct: 1792 CVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICN 1842
Score = 35.0 bits (79), Expect = 0.17
Identities = 24/101 (23%), Positives = 39/101 (38%), Gaps = 4/101 (3%)
Query: 207 CIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVMLK 266
C+W I+ ++ + F D Q+E C +++ V+DG L A+ C
Sbjct: 2034 CVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSS 2091
Query: 267 TGIGVIRMWADEGSRLSRFRMLFTSFVEPPCTSSTFFCHSN 307
+ IR +D FR + S P S+ C N
Sbjct: 2092 SNFMSIRFISDHSITRRGFRAEYYS--SPSNDSTNLLCLPN 2130
>gi|148539840 deleted in malignant brain tumors 1 isoform a precursor
[Homo sapiens]
Length = 1785
Score = 77.0 bits (188), Expect = 4e-14
Identities = 43/114 (37%), Positives = 63/114 (55%), Gaps = 6/114 (5%)
Query: 55 GHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGF 114
G F+SP YP +YP N +C++ +E R+ + F + ++ C +D++EV DGP+
Sbjct: 1389 GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRD---VQLEGGCNYDYIEVFDGPYRS 1445
Query: 115 SPLIDRYC-GVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYL 167
SPLI R C G + S+ FM I+F SD + GFRA+Y P D T L
Sbjct: 1446 SPLIARVCDGARGS--FTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDSTNL 1497
Score = 65.5 bits (158), Expect = 1e-10
Identities = 39/120 (32%), Positives = 63/120 (52%), Gaps = 3/120 (2%)
Query: 41 PATQCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFEC 100
P++ CG ++ ++G F+SP+YP YP N +C++ +E RI L F + +E C
Sbjct: 1134 PSSNCGGFLFYASGT-FSSPSYPAYYPNNAKCVWEIEVNSGYRINLGF-SNLKLEAHHNC 1191
Query: 101 RFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIP 160
FD++E+ DG S L+ + C + + S+ M I F SD + GF A Y+ P
Sbjct: 1192 SFDYVEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFP 1250
Score = 37.0 bits (84), Expect = 0.044
Identities = 15/51 (29%), Positives = 28/51 (54%)
Query: 207 CIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCS 257
C+W I+ +I L F + ++E + C ++V ++DGS + L K C+
Sbjct: 1164 CVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICN 1214
Score = 35.0 bits (79), Expect = 0.17
Identities = 24/101 (23%), Positives = 39/101 (38%), Gaps = 4/101 (3%)
Query: 207 CIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVMLK 266
C+W I+ ++ + F D Q+E C +++ V+DG L A+ C
Sbjct: 1406 CVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSS 1463
Query: 267 TGIGVIRMWADEGSRLSRFRMLFTSFVEPPCTSSTFFCHSN 307
+ IR +D FR + S P S+ C N
Sbjct: 1464 SNFMSIRFISDHSITRRGFRAEYYS--SPSNDSTNLLCLPN 1502
>gi|7019483 procollagen C-endopeptidase enhancer 2 [Homo sapiens]
Length = 415
Score = 76.6 bits (187), Expect = 5e-14
Identities = 57/206 (27%), Positives = 90/206 (43%), Gaps = 18/206 (8%)
Query: 41 PATQCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFEC 100
P CG + T G S +P YPPN +C + + + + L F +E C
Sbjct: 29 PVFTCG-GILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNF-RFIDLESDNLC 86
Query: 101 RFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIP 160
R+D ++V +G I R+CG P + S+G M ++ SD G GF A +S
Sbjct: 87 RYDFVDVYNGHAN-GQRIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMFSAAE 145
Query: 161 DPDF--TYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAK 218
+ Y GG+L+ P F+ ++ P V C+W I A
Sbjct: 146 PNERGDQYCGGLLDR-PSGSFKTPN-----------WPDRDYPA-GVTCVWHIVAPKNQL 192
Query: 219 IYLRFLDYQMEHSNECKRNFVAVYDG 244
I L+F + +E N C+ ++VAV++G
Sbjct: 193 IELKFEKFDVERDNYCRYDYVAVFNG 218
Score = 58.9 bits (141), Expect = 1e-08
Identities = 39/108 (36%), Positives = 53/108 (49%), Gaps = 3/108 (2%)
Query: 55 GHFASPNYPD-SYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEV-RDGPF 112
G F +PN+PD YP C++ + A Q IEL F E + +E CR+D++ V G
Sbjct: 163 GSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELKF-EKFDVERDNYCRYDYVAVFNGGEV 221
Query: 113 GFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIP 160
+ I +YCG P I S + I+F SD L GF Y F P
Sbjct: 222 NDARRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGFIGHYIFRP 269
Score = 38.1 bits (87), Expect = 0.020
Identities = 29/120 (24%), Positives = 55/120 (45%), Gaps = 6/120 (5%)
Query: 173 PIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSN 232
P+ C L+G G + S E P + C W I + L F +E N
Sbjct: 29 PVFTCGGILTGESGFIGS---EGFPGVYPPNS-KCTWKITVPEGKVVVLNFRFIDLESDN 84
Query: 233 ECKRNFVAVYDGSSSIENLKAKFCSTVANDVMLKTGIG-VIRMWADEGSRLSRFRMLFTS 291
C+ +FV VY+G ++ + + +FC T ++ +G +++M +D + + F +F++
Sbjct: 85 LCRYDFVDVYNGHANGQRI-GRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMFSA 143
>gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]
Length = 3487
Score = 70.5 bits (171), Expect = 4e-12
Identities = 38/109 (34%), Positives = 57/109 (52%), Gaps = 5/109 (4%)
Query: 51 TSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDG 110
TS G SP +P Y C +++EA P I++TFD E +D LEVRDG
Sbjct: 757 TSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRF-----KTEVNYDTLEVRDG 811
Query: 111 PFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFI 159
+PLI Y G + P + ST ++++ FS+D+ +GF+ +Y I
Sbjct: 812 RTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETI 860
Score = 67.0 bits (162), Expect = 4e-11
Identities = 69/291 (23%), Positives = 108/291 (37%), Gaps = 61/291 (20%)
Query: 55 GHFASPNYPDSYPPNKECIYILEAA-PRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFG 113
G SPN+P Y N C++I+ A P + I+L F+E E +D L V DG
Sbjct: 414 GIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEF-----DLERGYDTLTVGDGGQD 468
Query: 114 FSPLIDRYC--GVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKY--------------- 156
Y G P LI ST MW+ F +D LGF+A Y
Sbjct: 469 GDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPA 528
Query: 157 ---------------SFIPDPDFTYLG------------GILNP--IPDCQFELSGADGI 187
F P F +G P + C F + G+
Sbjct: 529 YGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGV 588
Query: 188 VRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSS 247
V S ++ G + C+W I A P+++I+L F D +E + +F+ + DG+++
Sbjct: 589 VLSPNYPEDY----GNHLHCVWLILARPESRIHLAFNDIDVEP----QFDFLVIKDGATA 640
Query: 248 IENLKAKFCSTVANDVMLKTG-IGVIRMWADEGSRLSRFRMLFTSFVEPPC 297
+ F + +G + + D + F + FT+F C
Sbjct: 641 EAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNEC 691
Score = 66.2 bits (160), Expect = 7e-11
Identities = 41/122 (33%), Positives = 58/122 (47%), Gaps = 5/122 (4%)
Query: 51 TSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDG 110
T G SPNYP+ YPP KEC + + +P I L F+ + +EP +D L + DG
Sbjct: 1450 TGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFN-IFNLEPG----YDFLHIYDG 1504
Query: 111 PFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGI 170
SPLI + G + P I S+ +++ F SD + GF Y+ P G I
Sbjct: 1505 RDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDPGSI 1564
Query: 171 LN 172
N
Sbjct: 1565 KN 1566
Score = 63.2 bits (152), Expect = 6e-10
Identities = 37/108 (34%), Positives = 58/108 (53%), Gaps = 6/108 (5%)
Query: 51 TSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDG 110
T + G S +YP SYP + C +++ P I LT + Y++ E ++D E+ DG
Sbjct: 2362 TDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVE--YFLS---EKQYDEFEIFDG 2416
Query: 111 PFGFSPLIDRYCGVKSPPLI-RSTGRFMWIKFSSDEELEGLGFRAKYS 157
P G SPL+ G S PLI S+ +++++SSD GF+ +YS
Sbjct: 2417 PSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYS 2464
Score = 62.4 bits (150), Expect = 1e-09
Identities = 36/117 (30%), Positives = 60/117 (51%), Gaps = 10/117 (8%)
Query: 51 TSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDG 110
TS G SPNYP+ Y + C++++ A P RI L F++ +EP +FD L ++DG
Sbjct: 583 TSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFND-IDVEP----QFDFLVIKDG 637
Query: 111 PFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRA-----KYSFIPDP 162
+P++ + G + P I S+G ++F +D GF +++ PDP
Sbjct: 638 ATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDP 694
Score = 58.5 bits (140), Expect = 1e-08
Identities = 57/225 (25%), Positives = 77/225 (34%), Gaps = 59/225 (26%)
Query: 55 GHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGF 114
G SP +P YP C + + A + RI+L F + E FD L V DGP
Sbjct: 35 GTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSF-----ALEEDFDVLSVFDGPPQP 89
Query: 115 SPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPD---------PDFT 165
L R G + P I S + ++ SD + GF A Y +P P+
Sbjct: 90 ENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNPGRLPNGI 149
Query: 166 YLGGILN-----------------------------------PIPDCQFE------LSGA 184
G N P+P C+ + L G
Sbjct: 150 QQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACGGTLRGQ 209
Query: 185 DGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQME 229
GI+ S E DC WTI A I L F+D+Q+E
Sbjct: 210 SGIISSPHFPSEYHNN----ADCTWTILAELGDTIALVFIDFQLE 250
Score = 55.1 bits (131), Expect = 2e-07
Identities = 63/259 (24%), Positives = 93/259 (35%), Gaps = 60/259 (23%)
Query: 44 QCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFD 103
+CG VR G SP YP Y N CI+ +EA I L H+ + + E D
Sbjct: 1270 ECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGL----HFLVFDTEEVH-D 1324
Query: 104 HLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYS------ 157
L + DGP L+ G P + ST + ++FS+D GF ++S
Sbjct: 1325 VLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATS 1384
Query: 158 ------------------------FIPDPDFTYLGG------------ILNPIP-----D 176
F DP + G P P
Sbjct: 1385 CNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIAP 1444
Query: 177 CQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNECKR 236
C +L+G G++ S E PG+ +C W + +P I L F + +E +
Sbjct: 1445 CGGDLTGPSGVILSP--NYPEPYPPGK--ECDWKVTVSPDYVIALVFNIFNLEPGYD--- 1497
Query: 237 NFVAVYDGSSSIENLKAKF 255
F+ +YDG S+ L F
Sbjct: 1498 -FLHIYDGRDSLSPLIGSF 1515
Score = 54.3 bits (129), Expect = 3e-07
Identities = 36/124 (29%), Positives = 58/124 (46%), Gaps = 13/124 (10%)
Query: 44 QCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHY-YIEPSFECRF 102
QCG V G SP +P +YP N +C + + + + F H ++ S E
Sbjct: 1967 QCGGTVEEMEGV-ILSPGFPGNYPSNMDCSWKIA------LPVGFGAHIQFLNFSTEPNH 2019
Query: 103 DHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDP 162
D++E+R+GP+ S ++ R+ G + P + ST + F SD GF+ +Y
Sbjct: 2020 DYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQ----- 2074
Query: 163 DFTY 166
D TY
Sbjct: 2075 DLTY 2078
Score = 52.0 bits (123), Expect = 1e-06
Identities = 63/247 (25%), Positives = 95/247 (38%), Gaps = 58/247 (23%)
Query: 44 QCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFE-CRF 102
+CG V T G SPN+P +Y N ECIY ++ P + I+L +FE
Sbjct: 1097 ECGNSV-TGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLK-------ARAFELSEG 1148
Query: 103 DHLEVRDGPFGFSPLIDRYCGVKSPPL-IRSTGRFMWIKFSSDEELEGLGFRAKY----- 156
D L+V DG + L+ + + + + ST +W+ F +D E GF +
Sbjct: 1149 DVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFEL 1208
Query: 157 --------------------------SFIPDPDFTYLGG--IL----------NPIPDCQ 178
SF DP ++ G +L P+P C
Sbjct: 1209 IKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCV 1268
Query: 179 FELSGADGIVRSSQVEQEEKTKPGQ-AVDCIWTIKATPKAKIYLRFLDYQMEHSNECKRN 237
E G S QV P + ++CIWTI+A I L FL + E ++ R
Sbjct: 1269 AECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLR- 1327
Query: 238 FVAVYDG 244
++DG
Sbjct: 1328 ---IWDG 1331
Score = 44.3 bits (103), Expect = 3e-04
Identities = 54/259 (20%), Positives = 94/259 (36%), Gaps = 51/259 (19%)
Query: 51 TSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDG 110
T G SP +P+ Y + C++ + I++ + E +D LEV DG
Sbjct: 1801 TERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQV-----VSFVTEQNWDSLEVFDG 1855
Query: 111 PFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKY-----SFIPDPDFT 165
++ + G P L+ ST +++ F SD + GF +Y S P+P
Sbjct: 1856 ADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVP 1915
Query: 166 YLG------GILNPIPDCQFE----------LSGADGIVR-------------SSQVEQE 196
G ++N + Q E +S G VR VE+
Sbjct: 1916 SNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGGTVEEM 1975
Query: 197 EKT--KPG------QAVDCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSI 248
E PG +DC W I +++FL++ S E +++ + +G
Sbjct: 1976 EGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNF----STEPNHDYIEIRNGPYET 2031
Query: 249 ENLKAKFCSTVANDVMLKT 267
+ +F + +L T
Sbjct: 2032 SRMMGRFSGSELPSSLLST 2050
Score = 39.7 bits (91), Expect = 0.007
Identities = 63/297 (21%), Positives = 114/297 (38%), Gaps = 63/297 (21%)
Query: 45 CGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDH 104
CG +++ S+G SP +PD YP N C +I+E + + + TF + E D+
Sbjct: 924 CGGFIQGSSGT-ILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFH-----LESGHDY 977
Query: 105 LEVRDGPFGFSPLIDRYCGVKSPPLIRS--TGRF-MWIKFSSDEELEGLGFR---AKYSF 158
L + + F+ + + G + P I + G F ++F SD + GF ++Y
Sbjct: 978 LLITENG-SFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDL 1036
Query: 159 IP--DPD---------------------------------FTYLGG----ILNPIPDCQF 179
P +P+ T LGG +P+P C
Sbjct: 1037 EPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVA 1096
Query: 180 ELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFV 239
E + + + + +CI++I+ P I L+ +++ + K
Sbjct: 1097 ECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVLK---- 1152
Query: 240 AVYDGSSSIENLKAKFCSTVANDVMLKTGIGVIRMWAD---EGSRLSR-FRMLFTSF 292
VYDG+++ L F + V L + +W D + S+ F + F+SF
Sbjct: 1153 -VYDGNNNSARLLGVFSHSEMMGVTLNSTSS--SLWLDFITDAENTSKGFELHFSSF 1206
Score = 38.1 bits (87), Expect = 0.020
Identities = 37/132 (28%), Positives = 55/132 (41%), Gaps = 10/132 (7%)
Query: 45 CGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDH 104
CG +R G +SP++P Y N +C + + A I L F I+ E +D
Sbjct: 202 CGGTLR-GQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVF-----IDFQLEDGYDF 255
Query: 105 LEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDF 164
LEV G G S + G P + S+ ++ + F+SD GF A+Y +
Sbjct: 256 LEV-TGTEGSSLW---FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIEL 311
Query: 165 TYLGGILNPIPD 176
G L P D
Sbjct: 312 KSRGVKLMPSKD 323
Score = 37.7 bits (86), Expect = 0.026
Identities = 33/122 (27%), Positives = 50/122 (40%), Gaps = 11/122 (9%)
Query: 55 GHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGF 114
G SPNYP +Y + C+Y + P+ + F + + + D +EV DG
Sbjct: 1628 GVVLSPNYPQNYTSGQICLYFV-TVPKDYV--VFGQFAFFHTALN---DVVEVHDGHSQH 1681
Query: 115 SPLIDRYCGV---KSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGIL 171
S L+ G +S PL +T + IKFS+ GF Y +P T +
Sbjct: 1682 SRLLSSLSGSHTGESLPL--ATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQCSSVP 1739
Query: 172 NP 173
P
Sbjct: 1740 EP 1741
Score = 35.8 bits (81), Expect = 0.099
Identities = 27/116 (23%), Positives = 52/116 (44%), Gaps = 7/116 (6%)
Query: 45 CGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDH 104
CG + +SNG + SP +P Y +++C++++ + L EPS D
Sbjct: 2182 CGGNITSSNGTVY-SPGFPSPYSSSQDCVWLITVPIGHGVRLNL-SLLQTEPS----GDF 2235
Query: 105 LEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIP 160
+ + DGP +P + + + ++S+ + +KF D G+ F +S P
Sbjct: 2236 ITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGI-FAIAFSAYP 2290
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,818,441
Number of Sequences: 37866
Number of extensions: 930817
Number of successful extensions: 2661
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 104
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 1876
Number of HSP's gapped (non-prelim): 545
length of query: 525
length of database: 18,247,518
effective HSP length: 107
effective length of query: 418
effective length of database: 14,195,856
effective search space: 5933867808
effective search space used: 5933867808
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.