Search of human proteins with 239758151

Search of human proteins with 239758151

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239758151 PREDICTED: hypothetical protein XP_002346314 [Homo
sapiens]
         (321 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239758151 PREDICTED: hypothetical protein XP_002346314 [Homo ...   640   0.0  
gi|239752632 PREDICTED: hypothetical protein XP_002347697 [Homo ...   467   e-132
gi|239758117 PREDICTED: hypothetical protein [Homo sapiens]           400   e-111
gi|239758008 PREDICTED: hypothetical protein XP_002346266 [Homo ...   357   8e-99
gi|239752579 PREDICTED: hypothetical protein XP_002348295 [Homo ...   315   3e-86
gi|239741651 PREDICTED: hypothetical protein XP_002342270 [Homo ...   271   6e-73
gi|239753329 PREDICTED: hypothetical protein XP_002345623 [Homo ...   253   2e-67
gi|239754599 PREDICTED: hypothetical protein [Homo sapiens]           241   8e-64
gi|239756562 PREDICTED: hypothetical protein [Homo sapiens]           239   2e-63
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]           122   4e-28
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]     54   1e-07
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]     54   1e-07
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]         54   2e-07
gi|4885379 histone cluster 1, H1e [Homo sapiens]                       53   3e-07
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        51   2e-06
gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens]             50   2e-06
gi|50409756 SRp25 nuclear protein isoform 1 [Homo sapiens]             49   6e-06
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]     49   8e-06
gi|153791662 coiled-coil domain containing 71 [Homo sapiens]           48   1e-05
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             47   2e-05
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi...    47   2e-05
gi|4885381 histone cluster 1, H1b [Homo sapiens]                       47   3e-05
gi|94536852 transmembrane cochlear-expressed protein 2 [Homo sap...    46   4e-05
gi|239751535 PREDICTED: hypothetical protein [Homo sapiens]            46   5e-05
gi|239746046 PREDICTED: hypothetical protein XP_002343643 [Homo ...    46   5e-05
gi|169658367 BAH domain and coiled-coil containing 1 [Homo sapiens]    45   1e-04
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            44   1e-04
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...    44   2e-04
gi|57529222 basic helix-loop-helix domain containing, class B, 4...    44   2e-04
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            44   3e-04

>gi|239758151 PREDICTED: hypothetical protein XP_002346314 [Homo
           sapiens]
          Length = 321

 Score =  640 bits (1651), Expect = 0.0
 Identities = 321/321 (100%), Positives = 321/321 (100%)

Query: 1   MSSPVLEPSPGPQSPYLHGLYLLLGEVLGHSALGAQHAQPANGDADELLELPALLQHLAG 60
           MSSPVLEPSPGPQSPYLHGLYLLLGEVLGHSALGAQHAQPANGDADELLELPALLQHLAG
Sbjct: 1   MSSPVLEPSPGPQSPYLHGLYLLLGEVLGHSALGAQHAQPANGDADELLELPALLQHLAG 60

Query: 61  CDPCASLRDSCVTPATALLLLSHRGQVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRS 120
           CDPCASLRDSCVTPATALLLLSHRGQVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRS
Sbjct: 61  CDPCASLRDSCVTPATALLLLSHRGQVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRS 120

Query: 121 GPRRCLSQDASRSGSRVCRSRPQTRGGGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRR 180
           GPRRCLSQDASRSGSRVCRSRPQTRGGGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRR
Sbjct: 121 GPRRCLSQDASRSGSRVCRSRPQTRGGGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRR 180

Query: 181 RGQKAAAAGAKSCGGGGKKPQKARAVGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQGE 240
           RGQKAAAAGAKSCGGGGKKPQKARAVGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQGE
Sbjct: 181 RGQKAAAAGAKSCGGGGKKPQKARAVGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQGE 240

Query: 241 KGRKKPRRRGQKAAAAGGERCKKPRRQKAAAVSAKSPKKPRRRVLNSARLGAESRKNPQR 300
           KGRKKPRRRGQKAAAAGGERCKKPRRQKAAAVSAKSPKKPRRRVLNSARLGAESRKNPQR
Sbjct: 241 KGRKKPRRRGQKAAAAGGERCKKPRRQKAAAVSAKSPKKPRRRVLNSARLGAESRKNPQR 300

Query: 301 RGQKSMAAKSRVGSGKIVEMG 321
           RGQKSMAAKSRVGSGKIVEMG
Sbjct: 301 RGQKSMAAKSRVGSGKIVEMG 321


>gi|239752632 PREDICTED: hypothetical protein XP_002347697 [Homo
           sapiens]
          Length = 231

 Score =  467 bits (1201), Expect = e-132
 Identities = 231/231 (100%), Positives = 231/231 (100%)

Query: 1   MSSPVLEPSPGPQSPYLHGLYLLLGEVLGHSALGAQHAQPANGDADELLELPALLQHLAG 60
           MSSPVLEPSPGPQSPYLHGLYLLLGEVLGHSALGAQHAQPANGDADELLELPALLQHLAG
Sbjct: 1   MSSPVLEPSPGPQSPYLHGLYLLLGEVLGHSALGAQHAQPANGDADELLELPALLQHLAG 60

Query: 61  CDPCASLRDSCVTPATALLLLSHRGQVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRS 120
           CDPCASLRDSCVTPATALLLLSHRGQVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRS
Sbjct: 61  CDPCASLRDSCVTPATALLLLSHRGQVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRS 120

Query: 121 GPRRCLSQDASRSGSRVCRSRPQTRGGGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRR 180
           GPRRCLSQDASRSGSRVCRSRPQTRGGGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRR
Sbjct: 121 GPRRCLSQDASRSGSRVCRSRPQTRGGGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRR 180

Query: 181 RGQKAAAAGAKSCGGGGKKPQKARAVGARRRGWKKLRRRGKKAAAAGGEKA 231
           RGQKAAAAGAKSCGGGGKKPQKARAVGARRRGWKKLRRRGKKAAAAGGEKA
Sbjct: 181 RGQKAAAAGAKSCGGGGKKPQKARAVGARRRGWKKLRRRGKKAAAAGGEKA 231


>gi|239758117 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 465

 Score =  400 bits (1027), Expect = e-111
 Identities = 245/376 (65%), Positives = 258/376 (68%), Gaps = 72/376 (19%)

Query: 1   MSSPVLEPSPGPQSPYLHGLYLLLGEVLGHSALGAQHAQPANGDADELLELPALLQHLAG 60
           MSSPVLEPSPGP+SPYLHG YLLLGEVLGHSALGAQHAQPANGDADELLELPALLQH  G
Sbjct: 1   MSSPVLEPSPGPRSPYLHGPYLLLGEVLGHSALGAQHAQPANGDADELLELPALLQHPTG 60

Query: 61  CDPCASLRDSCVTPATALLLLSHRGQVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRS 120
           CDPCASLRDS VTPATALLLLSHRG+ QRRS+QAAAAQEQS GRGCLGKEPP  ES TRS
Sbjct: 61  CDPCASLRDSRVTPATALLLLSHRGRAQRRSIQAAAAQEQSTGRGCLGKEPPSQESWTRS 120

Query: 121 GPRRCLSQDASRSGSRVCRSRPQTRGGGGKKP---------------------RRGQKAA 159
            PRRCLSQDA RSGSRVCRSRPQTRGGGGK+P                     RRGQKAA
Sbjct: 121 DPRRCLSQDAVRSGSRVCRSRPQTRGGGGKQPRRQKAAVAGAKSRGGEGKKPQRRGQKAA 180

Query: 160 TAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGG------GKK-----------PQK 202
           TAGAKSRGGGVRS GGKK+ RRGQK  AAGAK CGGG      G+K           PQK
Sbjct: 181 TAGAKSRGGGVRSLGGKKM-RRGQK-GAAGAKRCGGGKQPRRRGQKASKSGGVRCQTPQK 238

Query: 203 ARAVGARRRGWKKLRRRGKKAAAAGGE-KAGKKLRQQGEK----GRKKPRRRG------- 250
           A A G + R  KKLR+RG+KAAAAG E  AGK     GEK    G KKP R+        
Sbjct: 239 AAAQGVKSR--KKLRQRGQKAAAAGQEAAAGKTCGGGGEKHRGGGDKKPLRKNSRWRGQK 296

Query: 251 ---------QKAAAAGGERCKKPRRQKAAAVSAKSPKKPRRRVLNSARLGAESRKNPQRR 301
                    QKAAAAGGER KK RRQKAA   AKSPKKPR R  NS   G E        
Sbjct: 297 AAAAGGKKPQKAAAAGGERRKKLRRQKAAVARAKSPKKPRWRGQNSGN-GVE-------- 347

Query: 302 GQKSMAAKSRVGSGKI 317
           GQ+S+A       GK+
Sbjct: 348 GQRSLAFLEFDVEGKV 363



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 45/147 (30%), Positives = 67/147 (45%), Gaps = 39/147 (26%)

Query: 177 KIRRRGQKAAAAGAKSCGGG--GKKPQKARAVGARRRGWKKLRRRGKKAAAAGGEKAGKK 234
           + +RR  +AAAA  +S G G  GK+P         +  W   R   ++  +    ++G +
Sbjct: 86  RAQRRSIQAAAAQEQSTGRGCLGKEPPS-------QESWT--RSDPRRCLSQDAVRSGSR 136

Query: 235 LRQQGEKGRKKPRRRGQKAAAAGGERCKKPRRQKAAAVSAKSPKKPRRRVLNSARLGAES 294
           +       R +P+ RG      GG   K+PRRQKAA   AKS              G E 
Sbjct: 137 VC------RSRPQTRG-----GGG---KQPRRQKAAVAGAKSR-------------GGEG 169

Query: 295 RKNPQRRGQKSMAAKSRVGSGKIVEMG 321
           +K PQRRGQK+  A ++   G +  +G
Sbjct: 170 KK-PQRRGQKAATAGAKSRGGGVRSLG 195


>gi|239758008 PREDICTED: hypothetical protein XP_002346266 [Homo
           sapiens]
          Length = 316

 Score =  357 bits (916), Expect = 8e-99
 Identities = 219/335 (65%), Positives = 233/335 (69%), Gaps = 39/335 (11%)

Query: 1   MSSPVLEPSPGPQSPYLHGLYLLLGEVLGHSALGAQHAQPANGDADELLELPALLQHLAG 60
           MSSPVLEP+PGP+  YLH  YLLLGEVLGHSALGAQ AQ ANGDADELLELPALLQ  AG
Sbjct: 1   MSSPVLEPNPGPRPRYLHSPYLLLGEVLGHSALGAQPAQAANGDADELLELPALLQLPAG 60

Query: 61  CDPCASLRDSCVTPATALLLLSHRGQVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRS 120
           CDPCASLRDS VTPATALL LSHRG+ QRRSM AAAAQE+SLGRGCLGKEPP  ES TRS
Sbjct: 61  CDPCASLRDSRVTPATALLPLSHRGRAQRRSMHAAAAQERSLGRGCLGKEPPNRESWTRS 120

Query: 121 GPRRCLSQDASRSGSRVCRSRPQTRGGGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRR 180
            PR C+SQDASRSGSRVCRSRPQTRGGGGKKPRR QK A AGAKSR GG + R G+K RR
Sbjct: 121 DPRHCISQDASRSGSRVCRSRPQTRGGGGKKPRR-QKDAAAGAKSR-GGKKPRRGRKPRR 178

Query: 181 RGQKAAAAGAKSCGGGGKKP--QKARAVGA---------RRRGWKKLRRRGKKAAA---- 225
           RGQK+ AAGAKS G GGKKP  QK  A GA         RR G KK  R G++A A    
Sbjct: 179 RGQKSTAAGAKSRGEGGKKPRQQKPAAAGAKSGLGDKKSRRWGRKKPGRWGQEAVAGETC 238

Query: 226 AGGEKAGKKLRQQGEKGRKKPRRRGQKAAA-----AGGERCKKPRRQKAAAVSAKSPKKP 280
            GG K  +K    G K  KKPRR+ QKAAA     AG E C   R QKAAA  AKS    
Sbjct: 239 GGGGKKPQKAAAPGAKSHKKPRRQWQKAAAEKVAVAGAESC-GGRGQKAAAARAKS---- 293

Query: 281 RRRVLNSARLGAESRKNPQRRGQKSMAAKSRVGSG 315
                     G    K  +RRGQ+  A KSR G G
Sbjct: 294 ----------GGFGGKKQRRRGQR--APKSRGGRG 316


>gi|239752579 PREDICTED: hypothetical protein XP_002348295 [Homo
           sapiens]
          Length = 240

 Score =  315 bits (807), Expect = 3e-86
 Identities = 177/254 (69%), Positives = 191/254 (75%), Gaps = 17/254 (6%)

Query: 1   MSSPVLEPSPGPQSPYLHGLYLLLGEVLGHSALGAQHAQPANGDADELLELPALLQHLAG 60
           MSSPVLEP+PGP+  YLHG YLLLGEVLGHSALGAQ AQ ANGDADELLELPALLQ  AG
Sbjct: 1   MSSPVLEPNPGPRPRYLHGPYLLLGEVLGHSALGAQPAQAANGDADELLELPALLQLPAG 60

Query: 61  CDPCASLRDSCVTPATALLLLSHRGQVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRS 120
           CDPCASLRDS VTPATALL LSHRG+ QRRSM AAAAQE+SLGRGCLGKEPP  ES TRS
Sbjct: 61  CDPCASLRDSRVTPATALLPLSHRGRAQRRSMHAAAAQERSLGRGCLGKEPPNRESWTRS 120

Query: 121 GPRRCLSQDASRSGSRVCRSRPQTRGGGGKKPR-RGQKAATAGAKSRGGGVRSRGGKKIR 179
            PR C+SQDASRSGSRVCRSRPQTRG GGKK R RG+KAA          V++  G+  +
Sbjct: 121 DPRHCISQDASRSGSRVCRSRPQTRGSGGKKLRQRGEKAA---------AVKTCSGRSKK 171

Query: 180 RRGQKAAAAGAKSCGGGGKKPQKARAVGAR--RRGWKKLRRRGKKAAAAGGEKAGKKLRQ 237
              QKAA  GAKS GG GKKPQKA A GA+    G KKL R GKK       + G+K   
Sbjct: 172 PGRQKAAVMGAKSRGGRGKKPQKAAAAGAKSCNGGGKKLGRWGKKPG-----RRGQKAAV 226

Query: 238 QGEKGRKKPRRRGQ 251
            G K RKKP+RRGQ
Sbjct: 227 TGAKSRKKPQRRGQ 240



 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 67/164 (40%), Positives = 78/164 (47%), Gaps = 46/164 (28%)

Query: 177 KIRRRGQKAAAAGAKSCGGG--GKKPQKARA-----------VGARRRGWKKLRRRGKKA 223
           + +RR   AAAA  +S G G  GK+P    +             A R G +  R R +  
Sbjct: 86  RAQRRSMHAAAAQERSLGRGCLGKEPPNRESWTRSDPRHCISQDASRSGSRVCRSRPQTR 145

Query: 224 AAAGGEKAGKKLRQQGEK--------GR-KKPRRRGQKAAAAG----GERCKKPRRQKAA 270
            + G     KKLRQ+GEK        GR KKP R  QKAA  G    G R KKP  QKAA
Sbjct: 146 GSGG-----KKLRQRGEKAAAVKTCSGRSKKPGR--QKAAVMGAKSRGGRGKKP--QKAA 196

Query: 271 AVSAKS-----------PKKPRRRVLNSARLGAESRKNPQRRGQ 303
           A  AKS            KKP RR   +A  GA+SRK PQRRGQ
Sbjct: 197 AAGAKSCNGGGKKLGRWGKKPGRRGQKAAVTGAKSRKKPQRRGQ 240


>gi|239741651 PREDICTED: hypothetical protein XP_002342270 [Homo
           sapiens]
          Length = 337

 Score =  271 bits (693), Expect = 6e-73
 Identities = 183/318 (57%), Positives = 200/318 (62%), Gaps = 43/318 (13%)

Query: 19  GLYLLLGEVLGHSALGAQHAQPANGDADELLELPALLQHLAGCDPCASLRDSCVTPATAL 78
           G YLLLGEVLGHSALGAQ AQ ANGDADELLELPALLQ  AG  PCASLRDS VTPATAL
Sbjct: 12  GPYLLLGEVLGHSALGAQPAQAANGDADELLELPALLQRPAGRGPCASLRDSRVTPATAL 71

Query: 79  LLLSHRGQVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRSGPRRCLSQDASRSGSRVC 138
           LLLSH  + QRRSM+AAAAQE+S GR  LGKEP   ES TRS P RCLSQDA R+GS+VC
Sbjct: 72  LLLSHCSRAQRRSMRAAAAQERSPGRRRLGKEPLIRESWTRSAPWRCLSQDAGRAGSQVC 131

Query: 139 RSRPQTRGGGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGK 198
            S PQTRGGGGKK +R QKA   GAKSR         KK +  GQKAA AGAKS GGGGK
Sbjct: 132 GSSPQTRGGGGKKLQR-QKATVMGAKSR---------KKPQHWGQKAATAGAKSPGGGGK 181

Query: 199 KP---------QKARAVGARRRGWKKLRRRGKKAAAAGGEK------AGKKLRQQGEKGR 243
           KP         +K RA  +R  G KK RR  +K AAAG +       AG K R   E G 
Sbjct: 182 KPGQEKPAATGEKTRAAKSRGGGGKKPRR--EKPAAAGAKNPQKAAAAGAKFR---EAGG 236

Query: 244 KKPRRRGQKAAAAG----GERCKKPRRQKAAAVSAKSPKKPRRRVLNSARLGAESRKNPQ 299
           +KPR RGQKA  AG    G    KP++  AA       KKPRRR  +S   G E      
Sbjct: 237 RKPRWRGQKATEAGAKSRGGGGIKPQKPAAAGAKIHGGKKPRRRGQSSGN-GVE------ 289

Query: 300 RRGQKSMAAKSRVGSGKI 317
             GQ S+A       GK+
Sbjct: 290 --GQNSLAFLECDVEGKV 305


>gi|239753329 PREDICTED: hypothetical protein XP_002345623 [Homo
           sapiens]
          Length = 351

 Score =  253 bits (645), Expect = 2e-67
 Identities = 175/315 (55%), Positives = 191/315 (60%), Gaps = 48/315 (15%)

Query: 19  GLYLLLGEVLGHSALGAQHAQPANGDADELLELPALLQHLAGCDPCASLRDSCVTPATAL 78
           G YLLLGE +GHSALGAQ  Q A GDADELLELPALLQ  AG  PCA+LR   +TPA AL
Sbjct: 12  GPYLLLGEAVGHSALGAQPVQAAEGDADELLELPALLQRPAGRGPCATLRSHPITPAPAL 71

Query: 79  LLLSHRGQVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRSGPRRCLSQDASRSGSRVC 138
           LLLSH    QRRSMQA  A+  S GRG LGKEP + ES TRS PRRC  QDASR+GSRVC
Sbjct: 72  LLLSHSLPAQRRSMQATVAKAGSPGRGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRVC 131

Query: 139 RSRPQTRGGGGKKP-RRGQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGG 197
           RSRPQ RGGG KKP RRGQKA    AKSRGG     GGKK   RGQKAA AGAK      
Sbjct: 132 RSRPQNRGGGDKKPRRRGQKA----AKSRGG-----GGKK--PRGQKAAGAGAKK----- 175

Query: 198 KKPQKARAVGARRRGWKKLRRRGKKAAAAGGEK----AGKKLRQQGEK------GRKKPR 247
                           +K RRRG++AAAAGG+K    A  K R  G K      G+K  R
Sbjct: 176 ---------------HRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRR 220

Query: 248 RRGQKAAAAGGERCKKPRRQKAAAVSAKS--PKKPRRRVLNSARLG--AESRKNPQRRGQ 303
           RRGQKAA + G   KK  RQKAA    KS   KKP R        G   +SR     + Q
Sbjct: 221 RRGQKAAKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQ 280

Query: 304 KSMA--AKSRVGSGK 316
           K+ A  AKSR G G+
Sbjct: 281 KAAAAGAKSRGGRGE 295



 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 55/137 (40%), Positives = 68/137 (49%), Gaps = 21/137 (15%)

Query: 88  QRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRSGPRRCLSQDASRSGSRVCRSRPQTRGG 147
           +RR  +AAAA  + L +    K       S   G ++  +    +   R  +   ++RGG
Sbjct: 180 RRRGERAAAAGGKKLQKAAAAK-------SRGGGGKKTAAAGGKKPRRRRGQKAAKSRGG 232

Query: 148 GGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQ-------------KAAAAGAKSCG 194
           G KK  R QKAA  G KSRG     RGGKK R RGQ             KAAAAGAKS G
Sbjct: 233 GDKKLER-QKAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQKAAAAGAKSRG 291

Query: 195 GGGKKPQKARAVGARRR 211
           G G+KPQKA A   + R
Sbjct: 292 GRGEKPQKAEAGQGQNR 308


>gi|239754599 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 294

 Score =  241 bits (614), Expect = 8e-64
 Identities = 155/259 (59%), Positives = 169/259 (65%), Gaps = 29/259 (11%)

Query: 19  GLYLLLGEVLGHSALGAQHAQPANGDADELLELPALLQHLAGCDPCASLRDSCVTPATAL 78
           G YLLLGEV+GHSALGAQ AQ ANGDADELLEL ALLQ  AG  PCA+L   C+TPATAL
Sbjct: 12  GPYLLLGEVVGHSALGAQPAQAANGDADELLELSALLQPRAGRGPCATLSGRCITPATAL 71

Query: 79  LLLSHRGQVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRSGPRRCLSQDASRSGSRVC 138
           LLLSHR + Q R MQA AA+  S G G LGKEPP  ES T S PRRC  QDASR+GS VC
Sbjct: 72  LLLSHRLRAQCRPMQATAAEAGSPGLGRLGKEPPSRESWTGSAPRRCPCQDASRAGSGVC 131

Query: 139 RSRPQTRGGGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGK 198
           RSRPQ+RGGG +KPRR QKAA A AKS GG     GGKK RR  QK AAAG         
Sbjct: 132 RSRPQSRGGGSRKPRR-QKAAAAQAKSLGG-----GGKKPRR--QKCAAAG--------- 174

Query: 199 KPQKARAVGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQGEKGRKKPRRRGQKAAAAGG 258
             QKA A  +RR G KK RR G+KA  AG     KK ++    G K PRRR QKAA A  
Sbjct: 175 --QKAAAEESRRGGGKKPRRGGQKAVGAG----AKKPQKAAAAGTKTPRRRRQKAAKAA- 227

Query: 259 ERCKKPRRQKAAAVSAKSP 277
                   QKAAA  + +P
Sbjct: 228 -----VWGQKAAAGESLTP 241



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 47/136 (34%), Positives = 58/136 (42%), Gaps = 40/136 (29%)

Query: 185 AAAAGAKSCGGGGKKPQKARAVGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQGEKGRK 244
           AA AG+   G  GK+P         R  W     R  +       +AG  +       R 
Sbjct: 89  AAEAGSPGLGRLGKEPPS-------RESWTGSAPR--RCPCQDASRAGSGVC------RS 133

Query: 245 KPRRRGQKAAAAGGERCKKPRRQKAAAVSAKS----PKKPRRRVLNSARLGAESRKNPQR 300
           +P+ RG      GG R  KPRRQKAAA  AKS     KKPRR+   +A            
Sbjct: 134 RPQSRG------GGSR--KPRRQKAAAAQAKSLGGGGKKPRRQKCAAA------------ 173

Query: 301 RGQKSMAAKSRVGSGK 316
            GQK+ A +SR G GK
Sbjct: 174 -GQKAAAEESRRGGGK 188


>gi|239756562 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 235

 Score =  239 bits (610), Expect = 2e-63
 Identities = 144/232 (62%), Positives = 162/232 (69%), Gaps = 26/232 (11%)

Query: 6   LEPSPGPQSPYLHGLYLLLGEVLGHSALGAQHAQPANGDADELLELPALLQHLAGCDPCA 65
           L  + GP +PYL G YLLLGEV+GHSALGAQ AQ A    DE+LELPALLQ  AG  PCA
Sbjct: 3   LRQNRGPHTPYLQGPYLLLGEVVGHSALGAQPAQAA----DEVLELPALLQRPAGRRPCA 58

Query: 66  SLRDSCVTPATALLLLSHRGQVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRSGPRRC 125
           S R   +TPATALLLLSHRG+ +RRSMQAAAA+  S GR  +GK PP  ES TRS P+RC
Sbjct: 59  SHRGRRITPATALLLLSHRGRAERRSMQAAAAKAGSPGRRRVGKGPPSRESWTRSAPQRC 118

Query: 126 LSQDASRSGSRVCRSRPQTRGG-------------GGKKPRRGQKAATAGAKSRGGGVRS 172
            SQDA R+GSRVCRSRPQ+RGG             GGK+PRR QK A AGAKSRGG    
Sbjct: 119 PSQDAGRAGSRVCRSRPQSRGGQKAAASGAKRRGVGGKEPRR-QKPAAAGAKSRGG---- 173

Query: 173 RGGKKIRRRGQKAAAAGAKSCGGGGKKPQKARAVGARRR--GWKKLRRRGKK 222
           +  KK RRRGQKAA   AK+ GGGG KPQKA A GA+ R  G  K  RRG++
Sbjct: 174 KSHKKPRRRGQKAAP--AKNSGGGGNKPQKAAAAGAKNRGGGGGKKPRRGRR 223



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 53/146 (36%), Positives = 70/146 (47%), Gaps = 35/146 (23%)

Query: 177 KIRRRGQKAAAAGAKSCGGG--GKKPQKARAVGARRRGWKKLRRRGKKAAAAGGEKAGKK 234
           +  RR  +AAAA A S G    GK P         R  W +   +   +  AG  +AG +
Sbjct: 79  RAERRSMQAAAAKAGSPGRRRVGKGPPS-------RESWTRSAPQRCPSQDAG--RAGSR 129

Query: 235 LRQQGEKGRKKPRRRG-QKAAAAGGERC----KKPRRQKAAAVSAKSPKKPRRRVLNSAR 289
           +       R +P+ RG QKAAA+G +R     K+PRRQK AA  AKS             
Sbjct: 130 VC------RSRPQSRGGQKAAASGAKRRGVGGKEPRRQKPAAAGAKSR------------ 171

Query: 290 LGAESRKNPQRRGQKSMAAKSRVGSG 315
            G +S K P+RRGQK+  AK+  G G
Sbjct: 172 -GGKSHKKPRRRGQKAAPAKNSGGGG 196


>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 819

 Score =  122 bits (306), Expect = 4e-28
 Identities = 109/287 (37%), Positives = 138/287 (48%), Gaps = 64/287 (22%)

Query: 84  RGQVQRRSMQAAAAQEQSLGRGCL-----------GKEPPKWESSTRSG-------PRRC 125
           RG+  RR  +A+AA  +S G G             G++ P+W++  R         PR  
Sbjct: 364 RGKKPRRQ-KASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAPAAKPRGG 422

Query: 126 LSQDASRSGSRVCRSRP-QTRGGGGKKPRRG-----------------------QKAATA 161
            S+   R G +  +SR  ++R GGGKKPRR                        QKA+ A
Sbjct: 423 GSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAEAGAESRGDKKQGRQKASAA 482

Query: 162 GAKSRGGGVRSRGGKKIRRRGQKA-------AAAGAKSCGGGGKKPQKARAVGARRR-GW 213
           G KSRGGG++S  GK + RRGQKA        AAGAKS G    + QK    GA+ R G 
Sbjct: 483 GTKSRGGGLKSHSGKNLWRRGQKAEAAGEKATAAGAKSRGRKQPRRQKPAVAGAKSRVGG 542

Query: 214 KKLRRRGKKAAAAGGEKAGKKLRQQGEKGRKKPRRRGQKAAAA----GGERCKKPRRQKA 269
            K R+R K  AA      G   +Q    G  KPR+ GQ AAAA    GG+  K+P  QKA
Sbjct: 543 SKSRQRQKAVAAGATSHGGGGNKQSRGGGGNKPRQWGQTAAAAKTRGGGD--KQPGWQKA 600

Query: 270 AAVSAKS-----PKKPRRRVLNSARLGAESRKNPQRRGQKSMAAKSR 311
           AA   KS      KK  R+   +A  GA+SRK P RRGQK  AA  +
Sbjct: 601 AAGVTKSRSGDGGKKAWRQ--KAAGTGAKSRKKPWRRGQKDAAAAEK 645



 Score =  109 bits (272), Expect = 4e-24
 Identities = 114/290 (39%), Positives = 134/290 (46%), Gaps = 75/290 (25%)

Query: 84  RGQVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRSGPRRCLSQDASRSG-SRVCRSRP 142
           R +  RR   AA   +   G G   K+P K         +R   Q A+  G SRV +SR 
Sbjct: 221 RRKKHRRPKPAAGGAKSRRGGG---KKPQK---------QRRRGQKAATGGKSRVGKSR- 267

Query: 143 QTRGGGGKKPRR-GQKAATAGAKSRGGGVRS------------------------RGGKK 177
              GGG KK RR GQ AA AGAK RG                             RGGKK
Sbjct: 268 ---GGGDKKLRRQGQNAALAGAKRRGAATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKK 324

Query: 178 IRRRGQKAAAAGAKSCGGGGKKPQKARAVGARRRGWKKLRRRGK-----KAAAA------ 226
            RRRGQKA  A A     GG   QKA  VG + R  KK RRRGK     KA+AA      
Sbjct: 325 PRRRGQKATKAAAAGTKRGGGGQQKAAVVGVKSR--KKQRRRGKKPRRQKASAAGAKSRG 382

Query: 227 GGEKAGKKLRQQGEKGRKK-----PRRRGQKAAAA--GGERCKKPRRQKAAAVSAK---- 275
           GG+K G +  ++   GRKK     PRRR QKA AA   G   KKPRR+   A  ++    
Sbjct: 383 GGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAPAAKPRGGGSKKPRRRGPKAAKSRGGKS 442

Query: 276 ---SPKKPRRR----VLNSARLGAESRKNPQRRGQKSMAA--KSRVGSGK 316
                KKPRRR       +A  GAESR + ++  QK+ AA  KSR G  K
Sbjct: 443 RSGGGKKPRRRGQKARQKAAEAGAESRGDKKQGRQKASAAGTKSRGGGLK 492



 Score =  107 bits (268), Expect = 1e-23
 Identities = 111/305 (36%), Positives = 133/305 (43%), Gaps = 80/305 (26%)

Query: 86  QVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRSGPRRCLSQDASRSGSRVCRSRPQTR 145
           Q QRR  Q AA      G+  +GK     +   R   +      A R G+     +P  +
Sbjct: 246 QKQRRRGQKAATG----GKSRVGKSRGGGDKKLRRQGQNAALAGAKRRGAATAGEKPAAK 301

Query: 146 GGGGKKP------------------RRGQKA---ATAGAKSRGGG--------VRSRGGK 176
           G GG+ P                  RRGQKA   A AG K  GGG        V+SR  K
Sbjct: 302 GRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQQKAAVVGVKSR--K 359

Query: 177 KIRRRG-----QKAAAAGAKSCGGGGKK---PQKARAVGARRRGWKKLRRRGKKAAAAGG 228
           K RRRG     QKA+AAGAKS GGG KK     K R  G ++  W+  RRR +KA AA  
Sbjct: 360 KQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAPAAKP 419

Query: 229 EKAG-KKLRQQGEK------------GRKKPRRRGQKA----AAAGGERC--KKPRRQKA 269
              G KK R++G K            G KKPRRRGQKA    A AG E    KK  RQKA
Sbjct: 420 RGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAEAGAESRGDKKQGRQKA 479

Query: 270 AAVSAKSP----------------KKPRRRVLNSARLGAESR--KNPQRRGQKSMAAKSR 311
           +A   KS                 +K       +   GA+SR  K P+R+      AKSR
Sbjct: 480 SAAGTKSRGGGLKSHSGKNLWRRGQKAEAAGEKATAAGAKSRGRKQPRRQKPAVAGAKSR 539

Query: 312 VGSGK 316
           VG  K
Sbjct: 540 VGGSK 544



 Score =  101 bits (251), Expect = 1e-21
 Identities = 84/245 (34%), Positives = 114/245 (46%), Gaps = 42/245 (17%)

Query: 81  LSHRGQVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRSGPRRCLSQDASRSGSRVCRS 140
           + +RG  Q       A     LG   L + P +  + + +      +      GS   + 
Sbjct: 1   MDYRGHRQCNQAAGRAGPGAPLG-AALARTPVELAAESAAPALSAAAAGVKILGSGDKKL 59

Query: 141 RPQTRGGGGKKPR-RGQKAATAGAKSR--------GGGVRSRGGKKIRRRGQKAAAAGAK 191
           R Q    GGKK R RGQK A AG ++R         GG  +RGG +     QKAAAAG K
Sbjct: 60  RRQKAAAGGKKARLRGQKGAVAGKEARQHWQKAAGAGGAENRGGGE-----QKAAAAGTK 114

Query: 192 SCGGGGKKPQKARAVGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQGEKGRKKPRRRGQ 251
           S GG G+KP                RRRG+KAAA G +K   + ++    G K      Q
Sbjct: 115 SLGGRGRKP----------------RRRGQKAAATGSKKPRWRAQKSAAAGSKNRGAGAQ 158

Query: 252 KAAAAGGERC---KKPRRQKAAAVSAKSPKKPRRRVLNSARLGAESRKNPQRRGQKSMAA 308
           KAAAA G +    +KP++  AA   ++S KKPRRR       GA+SR +  ++G +   A
Sbjct: 159 KAAAAAGVKSQGGEKPQKAAAAGAKSRSGKKPRRR-------GAKSRGDEDKKG-RQREA 210

Query: 309 KSRVG 313
           KSR G
Sbjct: 211 KSRFG 215



 Score = 98.2 bits (243), Expect = 9e-21
 Identities = 95/279 (34%), Positives = 123/279 (44%), Gaps = 66/279 (23%)

Query: 91  SMQAAAAQEQSLGRGCLGKEPPKWESSTRSGPRRCLSQDASRSGSRVCRSRPQTRGGGGK 150
           ++ AAAA  + LG G   K+  + +++      R   Q  + +G    +   +  G GG 
Sbjct: 41  ALSAAAAGVKILGSG--DKKLRRQKAAAGGKKARLRGQKGAVAGKEARQHWQKAAGAGGA 98

Query: 151 KPRRG--QKAATAGAKSRGGGVR----------SRGGKKIRRRGQKAAAAGAKSCGGG-- 196
           + R G  QKAA AG KS GG  R          + G KK R R QK+AAAG+K+ G G  
Sbjct: 99  ENRGGGEQKAAAAGTKSLGGRGRKPRRRGQKAAATGSKKPRWRAQKSAAAGSKNRGAGAQ 158

Query: 197 ------------GKKPQKARAVGARRRGWKKLRRRGKKAAA------------------A 226
                       G+KPQKA A GA+ R  KK RRRG K+                     
Sbjct: 159 KAAAAAGVKSQGGEKPQKAAAAGAKSRSGKKPRRRGAKSRGDEDKKGRQREAKSRFGKTR 218

Query: 227 GGEK----------AGKKLRQQGEKGRKKPRRRGQKAAAAGGERCKKPRRQKAAAVSAKS 276
           GG +           G K R+ G K  +K RRRGQKAA  G  R  K R           
Sbjct: 219 GGRRKKHRRPKPAAGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSR--------GGG 270

Query: 277 PKKPRRRVLNSARLGAESRKNPQRRGQKSMAAKSRVGSG 315
            KK RR+  N+A  GA+ R+     G+K  AAK R G G
Sbjct: 271 DKKLRRQGQNAALAGAK-RRGAATAGEKP-AAKGRGGRG 307



 Score = 82.0 bits (201), Expect = 6e-16
 Identities = 71/202 (35%), Positives = 97/202 (48%), Gaps = 39/202 (19%)

Query: 89  RRSMQAAAAQEQSLGRGCL----GKEPPKWESSTRSGPRR----CLSQDASRSGSRVCRS 140
           RR  + AAA E++   G      G + P+W+    +G        + Q+A  +  +  R 
Sbjct: 634 RRGQKDAAAAEKAWATGATSRGSGGKQPRWQKPAAAGSESSAAAAVGQEAE-ARKKPRRR 692

Query: 141 RPQTRGGGG--------------KKPRRGQKAATAGAKSRG-GGVRSRGGKKIRRRGQKA 185
           R ++RG GG              KKPR G+     GAKSRG GG +SRG    + R  K 
Sbjct: 693 RAKSRGDGGQNAAVGINPWQRRGKKPRLGKSRGGGGAKSRGSGGAKSRGSGGAKSRSGKK 752

Query: 186 AAAGAKSCGGGGKKPQKARAVGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQGEKGRKK 245
           AAA +KS GGGG K  + R  GA+ R  +K    G + AAA G K   +++ +G      
Sbjct: 753 AAA-SKSHGGGGAK--RRRGGGAKSRSGEKAVTAGGQKAAAAGGKKPPRVKSRG------ 803

Query: 246 PRRRGQKAAAAGGERCKKPRRQ 267
              RGQKAAA G    KKP R+
Sbjct: 804 --GRGQKAAAGG----KKPLRR 819



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 94/331 (28%), Positives = 124/331 (37%), Gaps = 111/331 (33%)

Query: 80  LLSHRGQ-VQRRSMQAAAAQEQSLGRGCL--GKEPPKWESSTRSGPRRCLSQDASRSGSR 136
           L SH G+ + RR  +A AA E++   G    G++ P+ +    +G +  +    SR   +
Sbjct: 491 LKSHSGKNLWRRGQKAEAAGEKATAAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQK 550

Query: 137 VCRS---------RPQTRGGGGKKPRRGQKAATAGAKSRGGG-------------VRSRG 174
              +           Q+RGGGG KPR+  + A A AK+RGGG              +SR 
Sbjct: 551 AVAAGATSHGGGGNKQSRGGGGNKPRQWGQTAAA-AKTRGGGDKQPGWQKAAAGVTKSRS 609

Query: 175 G-------------------KKIRRRGQKAAAA-------GAKSCGGGGKKPQ------- 201
           G                   KK  RRGQK AAA       GA S G GGK+P+       
Sbjct: 610 GDGGKKAWRQKAAGTGAKSRKKPWRRGQKDAAAAEKAWATGATSRGSGGKQPRWQKPAAA 669

Query: 202 -----KARAVGARRRGWKKLRRRGKKAAAAGGEKA----------GKKLR---------- 236
                 A AVG      KK RRR  K+   GG+ A          GKK R          
Sbjct: 670 GSESSAAAAVGQEAEARKKPRRRRAKSRGDGGQNAAVGINPWQRRGKKPRLGKSRGGGGA 729

Query: 237 ---------QQGEKGRKK-----------------PRRRGQKAAAAGGERCKKPRRQKAA 270
                     +G  G K                   RRRG  A +  GE+      QKAA
Sbjct: 730 KSRGSGGAKSRGSGGAKSRSGKKAAASKSHGGGGAKRRRGGGAKSRSGEKAVTAGGQKAA 789

Query: 271 AVSAKSPKKPRRRVLNSARLGAESRKNPQRR 301
           A   K P + + R     +  A  +K P RR
Sbjct: 790 AAGGKKPPRVKSRGGRGQKAAAGGKK-PLRR 819


>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
          Length = 1512

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 58/249 (23%), Positives = 96/249 (38%), Gaps = 26/249 (10%)

Query: 74  PATALLLLSHRGQVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRSGPRRCLSQDASRS 133
           P   LL L+  G        AAAA   +    C    PP        G RR   +   R 
Sbjct: 54  PPPPLLFLAAPGTA------AAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGGRQKRRR 107

Query: 134 GSRVCRSRPQTRGGGGKKPRRGQKAATAGAKSRGG--------GVRSRGGKKIRRRGQKA 185
           G R  +   + R     +P   Q+    GA S GG         V S+  + +   G  A
Sbjct: 108 GPRAGQEAEKRRVFSLPQP---QQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASA 164

Query: 186 AAAGAKSCGGGGKKPQKARAVGARRRG---WKKLRRRGKKAAAAGGEKAGKKLRQQGEKG 242
           A A   + G GG     A + G +RRG    ++ RR  + ++    E+  +  R+ G++G
Sbjct: 165 ATAATAAGGTGGSGGSPASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRG 224

Query: 243 RKKPRRRGQKAAAAGGERCKKPRRQKAAAVSAKSPKKPRRRVLNSARLGAESRKNPQRRG 302
             +  +   + + +G ER       + A   + S    RR+  ++    + SRK+   + 
Sbjct: 225 GSEASKSRSRHSHSGEERA------EVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKA 278

Query: 303 QKSMAAKSR 311
            +S    S+
Sbjct: 279 HRSRTKSSK 287



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 45/190 (23%), Positives = 67/190 (35%), Gaps = 18/190 (9%)

Query: 94  AAAAQEQSLGRGCLGKEPPKWESSTRSGP---RRCLSQDASRSGSRVCRSRPQTRGGGGK 150
           AA A   + G G  G  P     + R G    RR      S SG    R R   R     
Sbjct: 164 AATAATAAGGTGGSGGSPASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHRR----- 218

Query: 151 KPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGKKPQKARAVGARR 210
             R GQ+  +  +KSR     SR       R + A +  + S GG  K      +  + R
Sbjct: 219 --RDGQRGGSEASKSR-----SRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSR 271

Query: 211 RGWKKLRRRGKKAAAAGGEKAGKKLRQQGEKGRKKP---RRRGQKAAAAGGERCKKPRRQ 267
           +       R +  ++     A K+  +   + + +P   RRR   +   G +      R 
Sbjct: 272 KDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRA 331

Query: 268 KAAAVSAKSP 277
             +  S KSP
Sbjct: 332 SQSLRSRKSP 341


>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
          Length = 1452

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 58/249 (23%), Positives = 96/249 (38%), Gaps = 26/249 (10%)

Query: 74  PATALLLLSHRGQVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRSGPRRCLSQDASRS 133
           P   LL L+  G        AAAA   +    C    PP        G RR   +   R 
Sbjct: 54  PPPPLLFLAAPGTA------AAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGGRQKRRR 107

Query: 134 GSRVCRSRPQTRGGGGKKPRRGQKAATAGAKSRGG--------GVRSRGGKKIRRRGQKA 185
           G R  +   + R     +P   Q+    GA S GG         V S+  + +   G  A
Sbjct: 108 GPRAGQEAEKRRVFSLPQP---QQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASA 164

Query: 186 AAAGAKSCGGGGKKPQKARAVGARRRG---WKKLRRRGKKAAAAGGEKAGKKLRQQGEKG 242
           A A   + G GG     A + G +RRG    ++ RR  + ++    E+  +  R+ G++G
Sbjct: 165 ATAATAAGGTGGSGGSPASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRG 224

Query: 243 RKKPRRRGQKAAAAGGERCKKPRRQKAAAVSAKSPKKPRRRVLNSARLGAESRKNPQRRG 302
             +  +   + + +G ER       + A   + S    RR+  ++    + SRK+   + 
Sbjct: 225 GSEASKSRSRHSHSGEERA------EVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKA 278

Query: 303 QKSMAAKSR 311
            +S    S+
Sbjct: 279 HRSRTKSSK 287



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 45/190 (23%), Positives = 67/190 (35%), Gaps = 18/190 (9%)

Query: 94  AAAAQEQSLGRGCLGKEPPKWESSTRSGP---RRCLSQDASRSGSRVCRSRPQTRGGGGK 150
           AA A   + G G  G  P     + R G    RR      S SG    R R   R     
Sbjct: 164 AATAATAAGGTGGSGGSPASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHRR----- 218

Query: 151 KPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGKKPQKARAVGARR 210
             R GQ+  +  +KSR     SR       R + A +  + S GG  K      +  + R
Sbjct: 219 --RDGQRGGSEASKSR-----SRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSR 271

Query: 211 RGWKKLRRRGKKAAAAGGEKAGKKLRQQGEKGRKKP---RRRGQKAAAAGGERCKKPRRQ 267
           +       R +  ++     A K+  +   + + +P   RRR   +   G +      R 
Sbjct: 272 KDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRA 331

Query: 268 KAAAVSAKSP 277
             +  S KSP
Sbjct: 332 SQSLRSRKSP 341


>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
          Length = 1312

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 68/255 (26%), Positives = 98/255 (38%), Gaps = 44/255 (17%)

Query: 88  QRRSMQAAAAQEQSLGRGCLGKEPPK-WESSTRSGPRRCLSQDASRSGSRVCRSRPQTRG 146
           ++RS +A  A   S G       P   W+S       R     AS S  R  RSR ++R 
Sbjct: 523 RKRSGEAKEAASSSSGTQPAPPAPASPWDSKKHRSRDRKPGSHASSSARRRSRSRSRSRS 582

Query: 147 GGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGKKPQ---KA 203
                 RR  ++     + RGG  RSR  +K RRR + A+   A S     ++ +   K 
Sbjct: 583 -----TRRRSRSTD---RRRGGSRRSRSREKRRRRRRSASPPPATSSSSSSRRERHRGKH 634

Query: 204 RAVGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQGEK---GRKKPRRRG---------- 250
           R  G  ++  K+ R RG+K +  G EKA             G +  RRRG          
Sbjct: 635 RDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGSTSCGDRDSRRRGAVPPSIQDLT 694

Query: 251 -------QKAAAAGGERCKKPRRQKAAAVSAKSPKKPRRRVL-------NSARLGAESRK 296
                  ++    G      PR    A  S+     P+R VL          R G  S+K
Sbjct: 695 DHDLFAIKRTITVGRLDKSDPRGPSPAPASS-----PKREVLYDSEGLSGEERGGKSSQK 749

Query: 297 NPQRRGQKSMAAKSR 311
           + +R G  S ++ SR
Sbjct: 750 DRRRSGAASSSSSSR 764



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 62/258 (24%), Positives = 92/258 (35%), Gaps = 60/258 (23%)

Query: 116 SSTRSGPRRCLSQDASRSGSRVCRSRPQTRG---GGGKKPRRGQKAATAGAKSRG----G 168
           S +RS  RR  S D  R GSR  RSR + R         P     +++   + RG    G
Sbjct: 578 SRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRSASPPPATSSSSSSRRERHRGKHRDG 637

Query: 169 GVRSRGGKKIRRRGQKAAAAGAKSCGGGGKKPQKARAVG---ARRRG------------- 212
           G   +  K+ R RG+K +  G++        P  + + G   +RRRG             
Sbjct: 638 GGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGSTSCGDRDSRRRGAVPPSIQDLTDHD 697

Query: 213 ------------WKKLRRRGKKAAAAGGEKA-------GKKLRQQGEKGRKKPRRRGQKA 253
                         K   RG   A A   K        G    ++G K  +K RRR   A
Sbjct: 698 LFAIKRTITVGRLDKSDPRGPSPAPASSPKREVLYDSEGLSGEERGGKSSQKDRRRSGAA 757

Query: 254 AAA--------------GGERCKKPRRQKAAAVSAKSPKKPRRRVLNSARLGAESRKNPQ 299
           +++              GG+R +   R +    S+K  + P+     SA       K P 
Sbjct: 758 SSSSSSREKGSRRKALDGGDRDRDRDRDRDRDRSSKKARPPK----ESAPSSGPPPKPPV 813

Query: 300 RRGQKSMAAKSRVGSGKI 317
             G  S ++ S   S K+
Sbjct: 814 SSGSGSSSSSSSCSSRKV 831



 Score = 32.0 bits (71), Expect = 0.76
 Identities = 40/152 (26%), Positives = 59/152 (38%), Gaps = 20/152 (13%)

Query: 111 PPKWESSTRSGPRR---CLSQDASRSGSRVCRSRP-QTRGGGGKKPRRGQKAATAGAKSR 166
           PPK ES+  SGP       S   S S S  C SR  + +       R G  + T    + 
Sbjct: 797 PPK-ESAPSSGPPPKPPVSSGSGSSSSSSSCSSRKVKLQSKVAVLIREGVSSTTPAKDAA 855

Query: 167 GGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGKKPQKARAVGARRRGWKKLRRRGKKAAAA 226
             G+ S G K  R R  ++            K  ++A    A+        ++ K  A A
Sbjct: 856 SAGLGSIGVKFSRDRESRSPFL---------KPDERAPTEMAKAAPGSTKPKKTKVKAKA 906

Query: 227 GGEKAGKKLRQQGEKGRKKPRRRGQKAAAAGG 258
           G +K       +G KG+ KP +  +K  + GG
Sbjct: 907 GAKKT------KGTKGKTKPSKTRKKVRSGGG 932



 Score = 30.4 bits (67), Expect = 2.2
 Identities = 52/272 (19%), Positives = 88/272 (32%), Gaps = 48/272 (17%)

Query: 88  QRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRSGPRRCLSQDASRSGSRVCRSRPQTRGG 147
           +R   + + ++E+   R      PP   SS+ S   R   +     GS+  + R ++RG 
Sbjct: 593 RRGGSRRSRSREKRRRRRRSASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGE 652

Query: 148 GGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRRG------------------------- 182
             K+   G + A A A    G   S G +  RRRG                         
Sbjct: 653 --KRSGDGSEKAPAPAPPPSGST-SCGDRDSRRRGAVPPSIQDLTDHDLFAIKRTITVGR 709

Query: 183 -----------------QKAAAAGAKSCGG---GGKKPQKARAVGARRRGWKKLRRRGKK 222
                            ++     ++   G   GGK  QK R            R +G +
Sbjct: 710 LDKSDPRGPSPAPASSPKREVLYDSEGLSGEERGGKSSQKDRRRSGAASSSSSSREKGSR 769

Query: 223 AAAAGGEKAGKKLRQQGEKGRKKPRRRGQKAAAAGGERCKKPRRQKAAAVSAKSPKKPRR 282
             A  G    +   +  ++ R   + R  K +A       KP     +  S+ S     R
Sbjct: 770 RKALDGGDRDRDRDRDRDRDRSSKKARPPKESAPSSGPPPKPPVSSGSGSSSSSSSCSSR 829

Query: 283 RVLNSARLGAESRKNPQRRGQKSMAAKSRVGS 314
           +V   +++    R+          AA + +GS
Sbjct: 830 KVKLQSKVAVLIREGVSSTTPAKDAASAGLGS 861



 Score = 29.3 bits (64), Expect = 4.9
 Identities = 30/137 (21%), Positives = 53/137 (38%), Gaps = 4/137 (2%)

Query: 182 GQKAAAAGAKSCGGGGKKPQKARAVGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQGEK 241
           G+ A A  A     GG   +  R +  +RR   + R      A A    AG   R++  +
Sbjct: 464 GEPAPAPPAADSRWGGLDLR--RKILTQRRERYRQRSPSPAPAPAPAAAAGPPTRKKSRR 521

Query: 242 GRKKPRRRGQKAAAAGGERCKKPRRQKA--AAVSAKSPKKPRRRVLNSARLGAESRKNPQ 299
            RK+     + A+++ G +   P       +       +KP     +SAR  + SR   +
Sbjct: 522 ERKRSGEAKEAASSSSGTQPAPPAPASPWDSKKHRSRDRKPGSHASSSARRRSRSRSRSR 581

Query: 300 RRGQKSMAAKSRVGSGK 316
              ++S +   R G  +
Sbjct: 582 STRRRSRSTDRRRGGSR 598



 Score = 29.3 bits (64), Expect = 4.9
 Identities = 22/86 (25%), Positives = 39/86 (45%), Gaps = 6/86 (6%)

Query: 148 GGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGKKPQKARAVG 207
           G  KP++ +  A AGAK   G   ++G  K  +  +K  + G     GG    +K++A  
Sbjct: 893 GSTKPKKTKVKAKAGAKKTKG---TKGKTKPSKTRKKVRSGGGSGGSGGQVSLKKSKADS 949

Query: 208 ARRRGWKKLRRRGKKAAAAGGEKAGK 233
             +    K     ++ + +G E+A K
Sbjct: 950 CSQAAGTK---GAEETSWSGEERAAK 972


>gi|4885379 histone cluster 1, H1e [Homo sapiens]
          Length = 219

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 41/138 (29%), Positives = 60/138 (43%), Gaps = 20/138 (14%)

Query: 143 QTRGGGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGKKPQK 202
           QT+G G     +  K A +G              + + + +KA AA AK   G  KKP+K
Sbjct: 95  QTKGTGASGSFKLNKKAASG--------------EAKPKAKKAGAAKAKKPAGAAKKPKK 140

Query: 203 ARAVGARRRGWKKLRRRGKK-AAAAGGEKAGKKLRQQGEKGRKKPRRRGQKAAAAGGERC 261
           A      ++  KK  ++ KK AAAAG +KA    + +  K +K P+   +  A       
Sbjct: 141 ATGAATPKKSAKKTPKKAKKPAAAAGAKKAKSPKKAKAAKPKKAPKSPAKAKAVK----- 195

Query: 262 KKPRRQKAAAVSAKSPKK 279
            K  + K A   A  PKK
Sbjct: 196 PKAAKPKTAKPKAAKPKK 213



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 47/163 (28%), Positives = 69/163 (42%), Gaps = 21/163 (12%)

Query: 164 KSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGKKPQKARAVGAR---------RRGWK 214
           KS G   R   G  +     KA AA  +  G      +KA A             + G K
Sbjct: 26  KSAGAAKRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSRIKLGLK 85

Query: 215 KLRRRGKKAAAAGGEKAGK-KLRQQGEKGRKKPRRRGQKAAAAGGER----CKKPRRQKA 269
            L  +G      G   +G  KL ++   G  KP+ +  KA AA  ++     KKP++   
Sbjct: 86  SLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKAK--KAGAAKAKKPAGAAKKPKKATG 143

Query: 270 AAVSAKSPKK-PRRRVLNSARLGAESRKNPQRRGQKSMAAKSR 311
           AA   KS KK P++    +A  GA+  K+P    +K+ AAK +
Sbjct: 144 AATPKKSAKKTPKKAKKPAAAAGAKKAKSP----KKAKAAKPK 182



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 29/107 (27%), Positives = 49/107 (45%), Gaps = 5/107 (4%)

Query: 140 SRPQTRGGGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQK-AAAAGAKSCGGGGK 198
           ++P+ +  G  K ++   AA    K+ G     +  KK  ++ +K AAAAGAK      K
Sbjct: 116 AKPKAKKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAKKPAAAAGAKKA----K 171

Query: 199 KPQKARAVGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQGEKGRKK 245
            P+KA+A   ++      + +  K  AA  + A  K  +  +   KK
Sbjct: 172 SPKKAKAAKPKKAPKSPAKAKAVKPKAAKPKTAKPKAAKPKKAAAKK 218


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 59/267 (22%), Positives = 100/267 (37%), Gaps = 44/267 (16%)

Query: 82  SHRGQVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRSGPRRCLSQDASRSGSRVCRSR 141
           SH     RR  ++ +      GR        +  S +RS   R      SRS  R  RSR
Sbjct: 472 SHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWR-----RSRSAQRWGRSR 526

Query: 142 PQTRGGGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRR----RGQKAAAAGAKSCGGGG 197
              R G  + P+R   + +   + RG    +R G+   R    RG+  +   A+      
Sbjct: 527 SPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRS 586

Query: 198 KKPQKARA------------------------VGARRRGWK----KLRRRGKKAAAAGGE 229
           + P + R+                          ARRR       + R R +  A   G 
Sbjct: 587 RTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGR 646

Query: 230 KAGKKLRQQGEKGRKKPRRRGQK-----AAAAGGERCKKPRRQKAAAVSAKSPKKPRRRV 284
              +   ++G    + P RRG+      A  +G  R + P R+  +   +++P++ R R 
Sbjct: 647 SRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRS--RSRTPRRGRSRS 704

Query: 285 LNSARLGAESRKNPQRRGQKSMAAKSR 311
            +  R G    + PQRRG+   +++ +
Sbjct: 705 RSLVRRGRSHSRTPQRRGRSGSSSERK 731



 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 58/237 (24%), Positives = 95/237 (40%), Gaps = 20/237 (8%)

Query: 82  SHRGQVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRSGPRRCLSQDASRSGSRV---- 137
           S     QRR    +A + +S  R    +   +  +  R G  R  +    RS SR     
Sbjct: 543 SRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRR 602

Query: 138 -CRSR-PQTRGGGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGG 195
             RSR P  RG    +    +++ T     R    RS   +  R R +  A  G      
Sbjct: 603 RSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRT 662

Query: 196 GGKKPQKARAVGARRRGWKKLR---RRGKKAAAAG--GEKAGKKLRQQGEKGRKKPRRRG 250
             ++ +      ARR G  + R   RRG+  +     G    + L ++G    + P+RRG
Sbjct: 663 PARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRG 722

Query: 251 QKAAAAGGERCKKPRRQKAAAVSAKSPKKPRRRV-------LNSARLGAESRKNPQR 300
           +  +++  ER  K R  +  + S  SP+  + R+       L+S R  A+SR + +R
Sbjct: 723 RSGSSS--ERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRR 777



 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 42/184 (22%), Positives = 73/184 (39%), Gaps = 14/184 (7%)

Query: 131 SRSGSRVCRSRPQTRGGGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGA 190
           +RS  R  R +  +     +  R    A     +SR      RG  +  R  Q   +  A
Sbjct: 461 NRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSR-SRSPQWRRSRSA 519

Query: 191 KSCGGGGKKPQKARAVGARRRGWKKLR---RRGKKAAAAGGEKAGKKLRQQGEKGRKKPR 247
           +  G      ++ R+   +R GW + R   RRG+  +A  G    +    +G    + P 
Sbjct: 520 QRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPA 579

Query: 248 RRGQKAAAAGGERCKKPRRQKAAAVSAKSPKKPRRRVLNSARLGAESRKNPQRRGQKSMA 307
           RRG+        R + P R+++    +++P + R R    AR G    + P RR  ++ +
Sbjct: 580 RRGR-------SRSRTPARRRS---RSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRS 629

Query: 308 AKSR 311
              R
Sbjct: 630 PVRR 633



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 50/221 (22%), Positives = 88/221 (39%), Gaps = 35/221 (15%)

Query: 113 KWESSTRSGPRRCLSQDASRSGSRVCRSRPQTRGGGGKKPRRGQKAATAGAKSRGGGVRS 172
           K + S    P R + +  S + ++  RSR +T    G    R  +   + +  R G  RS
Sbjct: 468 KRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRS 527

Query: 173 RGGKKIRRRGQKAAAAGAKSCGGGGKKPQKARAVGARRRGWKKLRRRGKKAAAAGGEKAG 232
                 +RRG+  +           ++P  +R+   +RRG  +  RRG+  + +   +  
Sbjct: 528 P-----QRRGRSRSP----------QRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGR 572

Query: 233 KKLRQQGEKGRKKP----------------RRRGQKAAAAGGERCKKPRRQKAAAVSAKS 276
            + R    +GR +                 R R +  A  G  R + P R+++     +S
Sbjct: 573 SRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRS---RTRS 629

Query: 277 PKKPRRRVLNSARLGAESR-KNPQRRGQKSMAAKSRVGSGK 316
           P + R R  + AR    SR + P RRG+      +R G  +
Sbjct: 630 PVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSR 670



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 55/243 (22%), Positives = 93/243 (38%), Gaps = 24/243 (9%)

Query: 84  RGQVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRSGPRRCLSQDASRSGSRVCRSR-- 141
           R   +RRS   +  + +S  R      P +    +RS       +  SR+ +R  RSR  
Sbjct: 618 RTPARRRSRTRSPVRRRSRSRS-----PARRSGRSRSRTPARRGRSRSRTPARRGRSRSR 672

Query: 142 -PQTRGGGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGKKP 200
            P  R G  +     ++  +     R G  RSR    + RRG+  +    +    G    
Sbjct: 673 TPARRSGRSRSRTPARRGRSRSRTPRRGRSRSR---SLVRRGRSHSRTPQRRGRSGSSSE 729

Query: 201 QKARAVGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQGEKGRKKPRRRGQKAAAAGGER 260
           +K ++  ++RR         KK+       + ++ R       K   R   + + +G   
Sbjct: 730 RKNKSRTSQRRSRSNSSPEMKKSRI-----SSRRSRSLSSPRSKAKSRLSLRRSLSGSSP 784

Query: 261 CKK------PRRQKAAA--VSAKSPKKPRRRVLNSARLGAESRKNPQRRGQKSMAAKSRV 312
           C K      PRR ++ +    AKS   PRR   +S+    +  K P R+   S +   +V
Sbjct: 785 CPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKV 844

Query: 313 GSG 315
            SG
Sbjct: 845 KSG 847



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 61/261 (23%), Positives = 96/261 (36%), Gaps = 45/261 (17%)

Query: 81   LSHRGQVQRRSMQAAAAQEQSLG------RGCLGKEPPKWESSTRSGPRRCLSQDASRSG 134
            L+ + ++ RRS  A+++ E          R      P   E S  S  RR  S   +++ 
Sbjct: 1697 LTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTT 1756

Query: 135  SRVCRS-RPQTRGGGGKKPR-RGQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKS 192
            SR  RS  P+ RG    + R R +K  T   + R G   S+   + R+R +  +    + 
Sbjct: 1757 SRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGS--SQSTSRRRQRSRSRSRVTRRR 1814

Query: 193  CGGGG------KKPQKARAVGARRRG--------------------WKKLRRRGKKAAAA 226
             GG G       + + +R    RRRG                    WK+ R R   A   
Sbjct: 1815 RGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHR 1874

Query: 227  GGEKAGKKLRQQGEKGRKKP--RRRGQKAAAAGGERCKKPRRQKAAAVSAKSPKKPRRRV 284
                    + ++  + R  P  RRR +        R    RR+  +  S  S ++ R R 
Sbjct: 1875 RSRSRTPLISRRRSRSRTSPVSRRRSR-------SRTSVTRRRSRSRASPVSRRRSRSRT 1927

Query: 285  LNSARLGAESRKNPQRRGQKS 305
                R  + SR    RR  +S
Sbjct: 1928 PPVTRRRSRSRTPTTRRRSRS 1948



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 48/223 (21%), Positives = 79/223 (35%), Gaps = 23/223 (10%)

Query: 109 KEPPK------WESSTRSGPRRCLSQDASRSGSRVCRSRPQTRGGGGKKPRRGQKAATAG 162
           + PPK        SS+ S P        SR  S    S       G  +       +   
Sbjct: 403 RSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNR 462

Query: 163 AKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGKKPQKARAVGARRRGWKKLRRRGKK 222
           +  R    +S      RR G+  + A AK      + P K     +R   W++ R   + 
Sbjct: 463 SHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRW 522

Query: 223 AAAAGGEKAGK----------KLRQQGEKGRKKPRRRG----QKAAAAGGERCKKPRRQK 268
             +   ++ G+          + R    +GR +  RRG    +  A  G  R + P R+ 
Sbjct: 523 GRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRG 582

Query: 269 AAAVSAKSPKKPRRRVLNSARLGAESRKNPQRRGQKSMAAKSR 311
            +   +++P + R R     R  + SR  P RRG+      +R
Sbjct: 583 RS--RSRTPARRRSRSRTPTRRRSRSR-TPARRGRSRSRTPAR 622



 Score = 37.4 bits (85), Expect = 0.018
 Identities = 55/247 (22%), Positives = 94/247 (38%), Gaps = 53/247 (21%)

Query: 112  PKWESSTRSGPRRCLSQDASRSGSRV-----CRSRPQTRGGGGKKP-------RRGQKAA 159
            P+ +S +R  PRR      SRSGS        R+ P+ + G    P       R   + +
Sbjct: 1583 PEVDSKSRLSPRR------SRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRS 1636

Query: 160  TAGAKSRGGGVRSRGGKKIRRRGQ-----KAAAAGAKSCGGGGKKPQKARAVGARRRGWK 214
             +G+ S+G G    G        +     + A  G++S      +P+       RRR  +
Sbjct: 1637 RSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRS----SPEPKTKSRTPPRRRSSR 1692

Query: 215  ---------KLRRRGKKAAAAGGEKAGKKLRQQ----------GEKGRKKPRRRGQKA-- 253
                     +L RR + A+++   ++    R +           EK R   RRR   +  
Sbjct: 1693 SSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPR 1752

Query: 254  ----AAAGGERCKKPRR-QKAAAVSAKSPKKPRRRVLNSARLGAESRKNPQRRGQKSMAA 308
                +  G     KPR  Q++ + S +   +  RR   S    + SR+  + R +  +  
Sbjct: 1753 TKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTR 1812

Query: 309  KSRVGSG 315
            + R GSG
Sbjct: 1813 RRRGGSG 1819



 Score = 28.5 bits (62), Expect = 8.4
 Identities = 38/193 (19%), Positives = 72/193 (37%), Gaps = 20/193 (10%)

Query: 122  PRRCLSQDASRSGSRVCRSRPQTRGGGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRR 181
            P R  S+  S    +     P+ R      P    K  T   + R G   S   K + R 
Sbjct: 1473 PSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTP-QRERSGSESSVDQKTVART 1531

Query: 182  --GQKAAAAGA-----KSCGGGGKKPQKARAVGARRRGWKKLRRRGKKAAAAGGEKAGKK 234
              GQ++ +  +     K      ++ +   +  ++ +    LR+R +  ++         
Sbjct: 1532 PLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSP-------- 1583

Query: 235  LRQQGEKGRKKPRRRGQKAAAAGGERCKKPRRQKAAAVSAKSPKKPRRRVL-NSARLGAE 293
              +   K R  PRR    ++    ++ +   R ++ + S+  PK P  R L   +R G+ 
Sbjct: 1584 --EVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSS 1641

Query: 294  SR-KNPQRRGQKS 305
            S+ + P   G  S
Sbjct: 1642 SKGRGPSPEGSSS 1654


>gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens]
          Length = 352

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 24/204 (11%)

Query: 133 SGSRVCRSR---PQTRGGGGKKPRRGQKAATAGAKSRGGGVR--SRGGKKIRRRGQKAAA 187
           +G R C +R   P     GG + R G    T G +++G G    SR   +   R + ++ 
Sbjct: 46  TGVRGCGARGPAPLLASAGGGRARDG----TWGVRTKGSGAALPSRPASRAAPRPEASSP 101

Query: 188 A-GAKSCGGGGKKPQKARA------VGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQGE 240
               +   GG   PQ  RA      VG+R+R   + R RG+     G EK  KK R+   
Sbjct: 102 PLPLEKARGGLSGPQGGRARGAMAHVGSRKRSRSRSRSRGR-----GSEKRKKKSRKDTS 156

Query: 241 KGRKKPRRRGQKAAAAGG--ERCKKPRRQKAAAVSAKSPKKPRRRVLNSARLGAESRKNP 298
           +       +G+KA+ A G  ER K+  R++  + S+ S         +S+   + S    
Sbjct: 157 RNCSASTSQGRKASTAPGAEERSKQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSSDGR 216

Query: 299 QRRGQ-KSMAAKSRVGSGKIVEMG 321
           ++RG+ K    K +    K+ + G
Sbjct: 217 KKRGKYKDKRRKKKKKRKKLKKKG 240



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 38/137 (27%), Positives = 66/137 (48%), Gaps = 22/137 (16%)

Query: 120 SGPRRCLSQDA-SRSGSRV-CRSRPQTRGGGGKKPRRGQKAATA---------GAK-SRG 167
           SGP+   ++ A +  GSR   RSR ++RG G +K ++  +  T+         G K S  
Sbjct: 113 SGPQGGRARGAMAHVGSRKRSRSRSRSRGRGSEKRKKKSRKDTSRNCSASTSQGRKASTA 172

Query: 168 GGVRSRGGKKIRRRGQKAAAAGAKSCGGGGKKPQKARAV---GARRRGWKKLRRRGKKAA 224
            G   R  +K RRR + ++++ + S          + +    G ++RG  K +RR KK  
Sbjct: 173 PGAEERSKQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSSDGRKKRGKYKDKRRKKK-- 230

Query: 225 AAGGEKAGKKLRQQGEK 241
                K  KKL+++G++
Sbjct: 231 -----KKRKKLKKKGKE 242



 Score = 37.0 bits (84), Expect = 0.023
 Identities = 48/205 (23%), Positives = 73/205 (35%), Gaps = 38/205 (18%)

Query: 139 RSRPQTRGGGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGK 198
           R+ P    GG ++ R   +A  A        +R+   +     G  +A  G + CG  G 
Sbjct: 3   RAGPAGEEGGAREGRLLPRAPGAWV------LRACAERAALEVGAASADTGVRGCGARGP 56

Query: 199 KPQKARAVGARRR-GWKKLRRRGKKAA---------------------------AAGGEK 230
            P  A A G R R G   +R +G  AA                              G +
Sbjct: 57  APLLASAGGGRARDGTWGVRTKGSGAALPSRPASRAAPRPEASSPPLPLEKARGGLSGPQ 116

Query: 231 AGKKLRQQGEKGRKKPRRRGQKAAAAGGERCKKPRRQKAAAVSAKSPKKPRRRVLNSARL 290
            G+        G +K  R   ++   G E+ KK  R+  +   + S  + R+    S   
Sbjct: 117 GGRARGAMAHVGSRKRSRSRSRSRGRGSEKRKKKSRKDTSRNCSASTSQGRKA---STAP 173

Query: 291 GAESR-KNPQRRGQKSMAAKSRVGS 314
           GAE R K   RR  +S ++ S   S
Sbjct: 174 GAEERSKQKARRRTRSSSSSSSSSS 198



 Score = 35.0 bits (79), Expect = 0.089
 Identities = 44/217 (20%), Positives = 79/217 (36%), Gaps = 42/217 (19%)

Query: 84  RGQVQRRSMQAAAAQEQSLGRGCLGKEPPK--------------WESSTRSGPRRCLSQD 129
           R   +R +++  AA   +  RGC  + P                W   T+       S+ 
Sbjct: 29  RACAERAALEVGAASADTGVRGCGARGPAPLLASAGGGRARDGTWGVRTKGSGAALPSRP 88

Query: 130 ASRSGSRVCRSRP-----QTRGG-----GGKKP-------RRGQKAATAGAKSRGGGVRS 172
           ASR+  R   S P     + RGG     GG+          R +  + + ++ RG     
Sbjct: 89  ASRAAPRPEASSPPLPLEKARGGLSGPQGGRARGAMAHVGSRKRSRSRSRSRGRGS---- 144

Query: 173 RGGKKIRRRGQKAAAAGAKSCGGGGKKPQKA-RAVGARRRGWKKLRRRGKKAAAAGGEKA 231
                  +R +K+    +++C     + +KA  A GA  R  +K RRR + ++++    +
Sbjct: 145 ------EKRKKKSRKDTSRNCSASTSQGRKASTAPGAEERSKQKARRRTRSSSSSSSSSS 198

Query: 232 GKKLRQQGEKGRKKPRRRGQKAAAAGGERCKKPRRQK 268
                            R ++       R KK +R+K
Sbjct: 199 SSSSSSSSSSSSSSSDGRKKRGKYKDKRRKKKKKRKK 235


>gi|50409756 SRp25 nuclear protein isoform 1 [Homo sapiens]
          Length = 360

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 49/190 (25%), Positives = 80/190 (42%), Gaps = 26/190 (13%)

Query: 133 SGSRVCRSR---PQTRGGGGKKPRRGQKAATAGAKSRGGGVR--SRGGKKIRRRGQKAAA 187
           +G R C +R   P     GG + R G    T G +++G G    SR   +   R + ++ 
Sbjct: 46  TGVRGCGARGPAPLLASAGGGRARDG----TWGVRTKGSGAALPSRPASRAAPRPEASSP 101

Query: 188 A-GAKSCGGGGKKPQKARA------VGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQGE 240
               +   GG   PQ  RA      VG+R+R   + R RG+     G EK  KK R+   
Sbjct: 102 PLPLEKARGGLSGPQGGRARGAMAHVGSRKRSRSRSRSRGR-----GSEKRKKKSRKDTS 156

Query: 241 KGRKKPRRRGQKAAAAGGERCKKPRRQKAAAVSAKSPKKPRRRVLNSARLGAESRKNPQR 300
           +       +G+KA+ A G          +  ++ +S +K RRR  +S+   + S  +   
Sbjct: 157 RNCSASTSQGRKASTAPGAEA-----SPSPCITERSKQKARRRTRSSSSSSSSSSSSSSS 211

Query: 301 RGQKSMAAKS 310
               S ++ S
Sbjct: 212 SSSSSSSSSS 221



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 41/145 (28%), Positives = 71/145 (48%), Gaps = 30/145 (20%)

Query: 120 SGPRRCLSQDA-SRSGSRV-CRSRPQTRGGGGKKPRR----------------GQKAATA 161
           SGP+   ++ A +  GSR   RSR ++RG G +K ++                G+KA+TA
Sbjct: 113 SGPQGGRARGAMAHVGSRKRSRSRSRSRGRGSEKRKKKSRKDTSRNCSASTSQGRKASTA 172

Query: 162 -GAK-SRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGKKPQKARAV---GARRRGWKKL 216
            GA+ S    +  R  +K RRR + ++++ + S          + +    G ++RG  K 
Sbjct: 173 PGAEASPSPCITERSKQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSSDGRKKRGKYKD 232

Query: 217 RRRGKKAAAAGGEKAGKKLRQQGEK 241
           +RR KK       K  KKL+++G++
Sbjct: 233 KRRKKK-------KKRKKLKKKGKE 250



 Score = 35.0 bits (79), Expect = 0.089
 Identities = 45/204 (22%), Positives = 71/204 (34%), Gaps = 37/204 (18%)

Query: 139 RSRPQTRGGGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGK 198
           R+ P    GG ++ R   +A  A        +R+   +     G  +A  G + CG  G 
Sbjct: 3   RAGPAGEEGGAREGRLLPRAPGAWV------LRACAERAALEVGAASADTGVRGCGARGP 56

Query: 199 KPQKARAVGARRR-GWKKLRRRGKKAA---------------------------AAGGEK 230
            P  A A G R R G   +R +G  AA                              G +
Sbjct: 57  APLLASAGGGRARDGTWGVRTKGSGAALPSRPASRAAPRPEASSPPLPLEKARGGLSGPQ 116

Query: 231 AGKKLRQQGEKGRKKPRRRGQKAAAAGGERCKKPRRQKAAAVSAKSPKKPRRRVLNSARL 290
            G+        G +K  R   ++   G E+ KK  R+  +   + S  + R+    S   
Sbjct: 117 GGRARGAMAHVGSRKRSRSRSRSRGRGSEKRKKKSRKDTSRNCSASTSQGRKA---STAP 173

Query: 291 GAESRKNPQRRGQKSMAAKSRVGS 314
           GAE+  +P    +    A+ R  S
Sbjct: 174 GAEASPSPCITERSKQKARRRTRS 197


>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
          Length = 494

 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 56/260 (21%), Positives = 102/260 (39%), Gaps = 25/260 (9%)

Query: 85  GQVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRSGPRRCLSQDASRSGSRV---CRSR 141
           G  +RRS   + +  +S  R    ++      S++S   +  S+  SRSGSR     RSR
Sbjct: 178 GSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSK--SRSRSRSGSRSRSKSRSR 235

Query: 142 PQTRGGGGKKPRRGQKAATAGAKSRGGGV-RSRGGKKIRRRGQKAAAAGAKSCGGGGKKP 200
            Q+R    K+  R      + ++S   G  RS+   +   + Q     G        +  
Sbjct: 236 SQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHK 295

Query: 201 QKA--------RAVGARRRGW--------KKLRRRGKKAAAAGGEKAGKKLRQQGE---K 241
            K+        R V   +RG         K LR+   ++ + GG ++  + R + +   K
Sbjct: 296 SKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRK 355

Query: 242 GRKKPRRRGQKAAAAGGERCKKPRRQKAAAVSAKSPKKPRRRVLNSARLGAESRKNPQRR 301
           GRK+ R   +  + +  +  +  +R       A S KK ++   + ++  + SR   + R
Sbjct: 356 GRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKER 415

Query: 302 GQKSMAAKSRVGSGKIVEMG 321
                 +  R G G+    G
Sbjct: 416 EHAKSESSQREGRGESENAG 435



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 46/239 (19%), Positives = 87/239 (36%), Gaps = 11/239 (4%)

Query: 84  RGQVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRS---GPRRCLSQDASRSGSR---- 136
           R   + RS   + +Q +S  +    + P K +S +RS   G  R  S+D +    +    
Sbjct: 223 RSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDN 282

Query: 137 --VCRSRPQTRGGGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRR--RGQKAAAAGAKS 192
               +SR  +R     K R   +      + RG   R R  +K  R  R +  +  G++S
Sbjct: 283 VGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRS 342

Query: 193 CGGGGKKPQKARAVGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQGEKGRKKPRRRGQK 252
                 K +  R    R R   + R R +  +    ++  K+  + G   +KK     + 
Sbjct: 343 RSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRS 402

Query: 253 AAAAGGERCKKPRRQKAAAVSAKSPKKPRRRVLNSARLGAESRKNPQRRGQKSMAAKSR 311
            + +      K R    +  S +  +        +    + SR N + +      ++SR
Sbjct: 403 QSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSR 461



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 44/217 (20%), Positives = 81/217 (37%), Gaps = 11/217 (5%)

Query: 85  GQVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRSGPRRCLSQDASRSGSRVCRSRPQT 144
           G+ + RS     ++ +S  R     +  + E   R    R  SQ+ S    R  RSR ++
Sbjct: 284 GKPKSRSPSRHKSKSKSRSRS----QERRVEEEKRGSVSRGRSQEKSL---RQSRSRSRS 336

Query: 145 RGGGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGKKPQKAR 204
           +GG   + R   K+       +     SR   + R + +++   G+K     G   +K +
Sbjct: 337 KGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKK 396

Query: 205 AVGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQGEKGRKKPRRRGQKAAAAGGERCKKP 264
               R +     R   K+   A  E + ++ R + E        R +  + +      KP
Sbjct: 397 EDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSK----SKP 452

Query: 265 RRQKAAAVSAKSPKKPRRRVLNSARLGAESRKNPQRR 301
                +   +KS  K R R  + +R  + S    + R
Sbjct: 453 NLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSR 489


>gi|153791662 coiled-coil domain containing 71 [Homo sapiens]
          Length = 467

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 56/227 (24%), Positives = 91/227 (40%), Gaps = 22/227 (9%)

Query: 83  HRGQVQRRSMQAAAAQ-EQSLGRGCLGKEPPKWESSTRSGPRRCLSQDASRSGSRVCRSR 141
           H+ Q  + S+  +  +  +S G+G     P     +T  GP+ CL++    +G R     
Sbjct: 196 HKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPK-CLTRKGPGAGPRRGSGH 254

Query: 142 PQ--TRGGGGKKPRRGQKAATAGAKSRGGGVR------SRGGKKIRRRGQKAAAAGAKSC 193
                R  G    RR +  +  G K+    V       +R   K+ R   KAA A AK+ 
Sbjct: 255 QSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAK 314

Query: 194 GGGGKKPQKARAVGARRRGWKKLRRRGKKAAAAGGEKA-GKKLRQQGEKGRKKPRRRGQK 252
               K   KA+A         +++ + K  AA    KA  K +R + +  R +PR RG+ 
Sbjct: 315 AAQVKAKAKAKAA--------QVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGRP 366

Query: 253 AAAAGGERCKKPRRQKAAAVSAKSPKKPRRRVL---NSARLGAESRK 296
             +A     +K ++ +   V  K  +    + L      RLG  S K
Sbjct: 367 KGSAKARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLGPRSPK 413


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 50/213 (23%), Positives = 83/213 (38%), Gaps = 29/213 (13%)

Query: 108 GKEPPKWESSTRSGPRRCLSQDASRSGSRVC-RSRPQTRGGGGKKPRRGQKAATAGAKSR 166
           G+   +  S +   P        SRS SR+  + R + R  G ++    +  + +G    
Sbjct: 249 GRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGW 308

Query: 167 GGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGKKPQKARAVGARRRGWKKLRRRGKKAAAA 226
           G   R+ G       GQ++ A G +  G     P K  +   R R          KAAAA
Sbjct: 309 GSPQRNGGS------GQRSGAHGGRP-GSAHSPPDKPSSPSPRVRD---------KAAAA 352

Query: 227 GGEKAGKKLRQQGEKGRKKPRRRGQKAAAAGGERCKKPRRQKAAAVSAKSPKKPRRRVLN 286
                 +       +     + RG +AA   G R ++ RR++ +  SA +P++  RR   
Sbjct: 353 APTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRR--- 409

Query: 287 SARLGAESRKNPQRRGQKSMA---AKSRVGSGK 316
                   R  P R   +S++   + S  GSG+
Sbjct: 410 ------RPRPAPPRGSSRSLSRARSSSDSGSGR 436



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 41/182 (22%), Positives = 65/182 (35%), Gaps = 30/182 (16%)

Query: 142 PQTRGGGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGKKPQ 201
           P  RG     PR    +   G ++ GG  R R  ++ RRR + +A+A             
Sbjct: 356 PPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASA------------- 402

Query: 202 KARAVGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQGEKGRKK------PRRRGQKAAA 255
                  RRRG    RRR + A   G  ++  + R   + G  +      P    ++   
Sbjct: 403 ------PRRRG----RRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHG 452

Query: 256 AGGERCK-KPRRQKAAAVSAKSPKKPRRRVLNSARLGAESRKNPQRRGQKSMAAKSRVGS 314
             G+R K +P R + A+ S       RR              +P+        +KSR  S
Sbjct: 453 GHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRS 512

Query: 315 GK 316
            +
Sbjct: 513 AE 514


>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
           sapiens]
          Length = 674

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 46/215 (21%), Positives = 85/215 (39%), Gaps = 15/215 (6%)

Query: 103 GRGCLGKEPPKWESSTRSGPRRCLSQDASRSGSRVCRSRPQTRGGGG--KKPRRGQKAAT 160
           GR    +      SS+ S  R   S+ +SRS SR       +R GGG  +  R  +  + 
Sbjct: 368 GRNASARRRSSSSSSSSSASRTSSSRSSSRSSSR-------SRRGGGYYRSGRHARSRSR 420

Query: 161 AGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGKKPQKARAVGARRRGWKKLRRRG 220
           + ++SR    RSR   + R RG++ +  G++      + P +    G RRR   +     
Sbjct: 421 SWSRSRS---RSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGD 477

Query: 221 KKAAAAGGEKAGKKLRQQGEKGRKKPRRRGQKAAAAGGERCKKPRRQKAAAVSAKSPKKP 280
           +      G +     R +        R R    + +      + R +  +   + SP   
Sbjct: 478 RYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPA 537

Query: 281 RRRVLN---SARLGAESRKNPQRRGQKSMAAKSRV 312
           R ++     S  +G + +K     G+++ AAK ++
Sbjct: 538 REKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKL 572


>gi|4885381 histone cluster 1, H1b [Homo sapiens]
          Length = 226

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 54/216 (25%), Positives = 89/216 (41%), Gaps = 34/216 (15%)

Query: 65  ASLRDSCVTPATALLLLSHRGQVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRSGPRR 124
           A+ R +   P + L+  +     +R  +  AA ++ +L  G  G +  K  S  + G + 
Sbjct: 33  AAKRKATGPPVSELITKAVAASKERNGLSLAALKK-ALAAG--GYDVEKNNSRIKLGLKS 89

Query: 125 CLSQDASRSGSRVCRSRPQTRGGGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQK 184
            +S+     G+ V     QT+G G     +  K A +G              + + + +K
Sbjct: 90  LVSK-----GTLV-----QTKGTGASGSFKLNKKAASG--------------EAKPKAKK 125

Query: 185 AAAAGAKSCGGGGKKPQKARAVGARRRGWKKLRRRGKKAAAAGGEKAGK-----KLRQQG 239
           A AA AK   G    P+KA+     ++  KK  ++ KK AAAG +K  K     K   + 
Sbjct: 126 AGAAKAKKPAGA--TPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAKP 183

Query: 240 EKGRKKPRRRGQKAAAAGGERCKKPRRQKAAAVSAK 275
           +K  K P +       A   +  KP+  K  A  AK
Sbjct: 184 KKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAK 219



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 50/181 (27%), Positives = 80/181 (44%), Gaps = 12/181 (6%)

Query: 144 TRGGGGKKPRRGQK-AATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGA----KSCGGGG- 197
           T+     K R G   AA   A + GG    +   +I+   +   + G     K  G  G 
Sbjct: 48  TKAVAASKERNGLSLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGS 107

Query: 198 -KKPQKARAVGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQGEKGRKKPRRRGQKAAAA 256
            K  +KA +  A+ +  K    + KK A A  +KA K      +K  KK  ++ +K AAA
Sbjct: 108 FKLNKKAASGEAKPKAKKAGAAKAKKPAGATPKKAKKAAG--AKKAVKKTPKKAKKPAAA 165

Query: 257 GGER-CKKPRRQKAAAVSAKSPKKPRRRVLNSARLGAESRKNPQRRGQKSMAAKSRVGSG 315
           G ++  K P++ KAAA   K+ K P +    + +  A   K  + +  K  AAK++  + 
Sbjct: 166 GVKKVAKSPKKAKAAAKPKKATKSPAKP--KAVKPKAAKPKAAKPKAAKPKAAKAKKAAA 223

Query: 316 K 316
           K
Sbjct: 224 K 224


>gi|94536852 transmembrane cochlear-expressed protein 2 [Homo
           sapiens]
          Length = 906

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 40/144 (27%), Positives = 67/144 (46%), Gaps = 10/144 (6%)

Query: 156 QKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGG--GGKKPQKARAVGARRRGW 213
           ++ A  G K R        G ++ RR     A  A+   G  G ++ QK RA G+   G 
Sbjct: 9   KEEARGGVKGRVKSGSPHTGDRLGRRSSSKRALKAEGTPGRRGAQRSQKERAGGSPSPGS 68

Query: 214 KKLRRRGKKAAAAGGEKAGKKLRQQGEKGRKKPRRRGQKAAAAGGERCKKPRRQK---AA 270
            + ++ G++      E+ G++ R + E+  +  R+R ++A+    ER   P+R+K     
Sbjct: 69  PRRKQTGRRRHR---EELGEQERGEAERTCEGRRKRDERASFQ--ERTAAPKREKEIPRR 123

Query: 271 AVSAKSPKKPRRRVLNSARLGAES 294
              +K  KKPR   L S+  G ES
Sbjct: 124 EEKSKRQKKPRSSSLASSASGGES 147



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 35/153 (22%), Positives = 63/153 (41%), Gaps = 23/153 (15%)

Query: 115 ESSTRSGPRRCLSQDASRSGSRVCRSRPQTRG------GGGKKPRRGQKAATAGAKSRGG 168
           +   R G +  +   +  +G R+ R     R        G +  +R QK    G+ S G 
Sbjct: 9   KEEARGGVKGRVKSGSPHTGDRLGRRSSSKRALKAEGTPGRRGAQRSQKERAGGSPSPGS 68

Query: 169 GVRSRGGKKIRRR--GQKAAAAGAKSCGGGGKKPQKARAVGARRRGWKKLRRRGKKAAAA 226
             R + G++  R   G++      ++C G  K+ ++A                 ++ AA 
Sbjct: 69  PRRKQTGRRRHREELGEQERGEAERTCEGRRKRDERASFQ--------------ERTAAP 114

Query: 227 GGEKAGKKLRQQGEKGRKKPRRRGQKAAAAGGE 259
             EK   + R++  K +KKPR     ++A+GGE
Sbjct: 115 KREKEIPR-REEKSKRQKKPRSSSLASSASGGE 146



 Score = 32.7 bits (73), Expect = 0.44
 Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 6/96 (6%)

Query: 219 RGKKAAAAGGEKAGKK--LRQQGEK-GRKKPRRRGQKAAAAGGERCKKPRRQKAAAVSAK 275
           +G K  A GG K   K      G++ GR+   +R  KA    G R  + R QK  A  + 
Sbjct: 6   KGLKEEARGGVKGRVKSGSPHTGDRLGRRSSSKRALKAEGTPGRRGAQ-RSQKERAGGSP 64

Query: 276 SPKKPRRRVLNSARLGAESRKNPQRRGQKSMAAKSR 311
           SP  PRR+   + R         Q RG+     + R
Sbjct: 65  SPGSPRRK--QTGRRRHREELGEQERGEAERTCEGR 98


>gi|239751535 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 255

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 53/186 (28%), Positives = 70/186 (37%), Gaps = 43/186 (23%)

Query: 94  AAAAQEQSLGRGCLGKEPPKWESSTRSGPRRCLSQDASR-SGSRVCRSR-------PQTR 145
           A  +++   G G   + P  + S++ S   R   + AS     R+C  R       P  R
Sbjct: 102 AQGSRDVPAGPGFPPRLPRPFTSASFSNQTRLRRRSASALPAPRLCPQRASPGCSSPGVR 161

Query: 146 G-GGGKKPRR--GQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGKKPQK 202
           G GGG  PR   G  AA   A+   GG RSR           A  AG  +     + P++
Sbjct: 162 GPGGGASPRARGGNAAAALAARQAAGGGRSR----------SAFVAGRDAALACAQLPRR 211

Query: 203 ARAVGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQGEKGRKKPRRRGQKAAAAGGERCK 262
            R  GA         RRG +     GE             R  PR RG   A A G R  
Sbjct: 212 PRGAGA---------RRGMRRRLGAGE-------------RPAPRPRGPPRAPARGARWL 249

Query: 263 KPRRQK 268
           +PRR +
Sbjct: 250 RPRRPR 255



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 64/242 (26%), Positives = 85/242 (35%), Gaps = 61/242 (25%)

Query: 122 PRRCLSQDASRSGSRVCRSRPQTRGGGGKKPRRGQKAATAGA------KSRGGGVRSRGG 175
           P  C  +     GS+     P  R   G  PR G     AG       ++RGGG  +R  
Sbjct: 10  PSLCTPRVQCIRGSQRVPQPPAARSPRG--PRAGGGGGDAGGGGAPVRRARGGGCWARAY 67

Query: 176 KKIRRRGQKAAAAGAKSCGGGGKKPQKARAVGARRRGWK--------------------- 214
           +  R  G+        S G G   P + RA     +G +                     
Sbjct: 68  QDARCFGRGEGGDLQVSSGPGAAPPAEFRASARSAQGSRDVPAGPGFPPRLPRPFTSASF 127

Query: 215 ----KLRRRGKKA----------AAAGGEKAGKKLRQQGEKGRKKPRRRGQKAA------ 254
               +LRRR   A          A+ G    G +    G  G   PR RG  AA      
Sbjct: 128 SNQTRLRRRSASALPAPRLCPQRASPGCSSPGVR----GPGGGASPRARGGNAAAALAAR 183

Query: 255 -AAGGERCKKP--RRQKAAAVSAKSPKKPR----RRVLNSARLGAESRKNPQRRGQKSMA 307
            AAGG R +      + AA   A+ P++PR    RR +   RLGA  R  P+ RG     
Sbjct: 184 QAAGGGRSRSAFVAGRDAALACAQLPRRPRGAGARRGMR-RRLGAGERPAPRPRGPPRAP 242

Query: 308 AK 309
           A+
Sbjct: 243 AR 244



 Score = 29.3 bits (64), Expect = 4.9
 Identities = 37/156 (23%), Positives = 60/156 (38%), Gaps = 21/156 (13%)

Query: 181 RGQKAAAAGAKSCGGGGKKPQKARAVGARRRGWKKLRRRGK-----------KAAAAGGE 229
           RG +A   G  + GGGG   ++AR  G   R ++  R  G+             AA   E
Sbjct: 36  RGPRAGGGGGDA-GGGGAPVRRARGGGCWARAYQDARCFGRGEGGDLQVSSGPGAAPPAE 94

Query: 230 KAGKKLRQQGEK----GRKKPRRRGQKAAAAGGERCKKPRRQKAAAVSAK--SPKKPRRR 283
                   QG +    G   P R  +   +A      + RR+ A+A+ A    P++    
Sbjct: 95  FRASARSAQGSRDVPAGPGFPPRLPRPFTSASFSNQTRLRRRSASALPAPRLCPQRASPG 154

Query: 284 VLNSARLGAESRKNPQRRG---QKSMAAKSRVGSGK 316
             +    G     +P+ RG     ++AA+   G G+
Sbjct: 155 CSSPGVRGPGGGASPRARGGNAAAALAARQAAGGGR 190


>gi|239746046 PREDICTED: hypothetical protein XP_002343643 [Homo
           sapiens]
          Length = 255

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 53/186 (28%), Positives = 70/186 (37%), Gaps = 43/186 (23%)

Query: 94  AAAAQEQSLGRGCLGKEPPKWESSTRSGPRRCLSQDASR-SGSRVCRSR-------PQTR 145
           A  +++   G G   + P  + S++ S   R   + AS     R+C  R       P  R
Sbjct: 102 AQGSRDVPAGPGFPPRLPRPFTSASFSNQTRLRRRSASALPAPRLCPQRASPGCSSPGVR 161

Query: 146 G-GGGKKPRR--GQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGKKPQK 202
           G GGG  PR   G  AA   A+   GG RSR           A  AG  +     + P++
Sbjct: 162 GPGGGASPRARGGNAAAALAARQAAGGGRSR----------SAFVAGRDAALACAQLPRR 211

Query: 203 ARAVGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQGEKGRKKPRRRGQKAAAAGGERCK 262
            R  GA         RRG +     GE             R  PR RG   A A G R  
Sbjct: 212 PRGAGA---------RRGMRRRLGAGE-------------RPAPRPRGPPRAPARGARWL 249

Query: 263 KPRRQK 268
           +PRR +
Sbjct: 250 RPRRPR 255



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 64/242 (26%), Positives = 85/242 (35%), Gaps = 61/242 (25%)

Query: 122 PRRCLSQDASRSGSRVCRSRPQTRGGGGKKPRRGQKAATAGA------KSRGGGVRSRGG 175
           P  C  +     GS+     P  R   G  PR G     AG       ++RGGG  +R  
Sbjct: 10  PSLCTPRVQCIRGSQRVPQPPAARSPRG--PRAGGGGGDAGGGGAPVRRARGGGCWARAY 67

Query: 176 KKIRRRGQKAAAAGAKSCGGGGKKPQKARAVGARRRGWK--------------------- 214
           +  R  G+        S G G   P + RA     +G +                     
Sbjct: 68  QDARCFGRGEGGDLQVSSGPGAAPPAEFRASARSAQGSRDVPAGPGFPPRLPRPFTSASF 127

Query: 215 ----KLRRRGKKA----------AAAGGEKAGKKLRQQGEKGRKKPRRRGQKAA------ 254
               +LRRR   A          A+ G    G +    G  G   PR RG  AA      
Sbjct: 128 SNQTRLRRRSASALPAPRLCPQRASPGCSSPGVR----GPGGGASPRARGGNAAAALAAR 183

Query: 255 -AAGGERCKKP--RRQKAAAVSAKSPKKPR----RRVLNSARLGAESRKNPQRRGQKSMA 307
            AAGG R +      + AA   A+ P++PR    RR +   RLGA  R  P+ RG     
Sbjct: 184 QAAGGGRSRSAFVAGRDAALACAQLPRRPRGAGARRGMR-RRLGAGERPAPRPRGPPRAP 242

Query: 308 AK 309
           A+
Sbjct: 243 AR 244



 Score = 29.3 bits (64), Expect = 4.9
 Identities = 37/156 (23%), Positives = 60/156 (38%), Gaps = 21/156 (13%)

Query: 181 RGQKAAAAGAKSCGGGGKKPQKARAVGARRRGWKKLRRRGK-----------KAAAAGGE 229
           RG +A   G  + GGGG   ++AR  G   R ++  R  G+             AA   E
Sbjct: 36  RGPRAGGGGGDA-GGGGAPVRRARGGGCWARAYQDARCFGRGEGGDLQVSSGPGAAPPAE 94

Query: 230 KAGKKLRQQGEK----GRKKPRRRGQKAAAAGGERCKKPRRQKAAAVSAK--SPKKPRRR 283
                   QG +    G   P R  +   +A      + RR+ A+A+ A    P++    
Sbjct: 95  FRASARSAQGSRDVPAGPGFPPRLPRPFTSASFSNQTRLRRRSASALPAPRLCPQRASPG 154

Query: 284 VLNSARLGAESRKNPQRRG---QKSMAAKSRVGSGK 316
             +    G     +P+ RG     ++AA+   G G+
Sbjct: 155 CSSPGVRGPGGGASPRARGGNAAAALAARQAAGGGR 190


>gi|169658367 BAH domain and coiled-coil containing 1 [Homo sapiens]
          Length = 2608

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 89/345 (25%), Positives = 138/345 (40%), Gaps = 55/345 (15%)

Query: 10   PGPQSPYLHGLYLLLGEVLGHSALGAQHAQPANGDADELLELPALLQHLAGCDPCASL-- 67
            P P S  +HG+ LL    L   A+  Q ++    + +E + L   LQHLA      SL  
Sbjct: 1294 PLPHSSGIHGIALL--SELADLAIQRQRSERTVPEEEEDV-LAFNLQHLATLATAWSLVE 1350

Query: 68   ---RDSCVTPATALLL-------LSHRGQVQRRS------------MQAAAAQ--EQSLG 103
                DS   PA            L+ R Q+ +R             ++AA  +   Q +G
Sbjct: 1351 AAGLDSSTAPAQPPTANPCSGPRLTPRMQILQRKDTWTPKTKPVCPLKAAIDRLDTQEVG 1410

Query: 104  -RGCLGKEPPKWESSTRSGPRRCLSQDASRSGSRVCRSRPQTRGGGGKKPRRGQKAATAG 162
             R  L +   +++   R   R     D  R  S    SR   R G G+ PR+ + +++  
Sbjct: 1411 MRVRLAELQRRYKEKQRELARLQRKHDHERDES----SRSPARRGPGR-PRKRKHSSSLP 1465

Query: 163  AKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGKKPQK-----ARAVGARRRGWKKLR 217
            A    G +    GKK++          A+  GG G +P K      R+V A  +     +
Sbjct: 1466 APRPTGPLPRSDGKKVKAVRTSLGLLCAELRGGSGGEPAKKRSKLERSVYAGLQTASVEK 1525

Query: 218  RRGKKAAAAGG--EKAGKKLRQQGEKGRKKPRRRG-----QKAAAAGGERCKKPRRQKAA 270
             + KK++  GG       ++ Q   K + K    G     QK A  GG   +K  R K+A
Sbjct: 1526 AQCKKSSCQGGLAPSVAHRVAQLKPKVKSKGLPTGLSSFQQKEATPGGRIREKLSRAKSA 1585

Query: 271  AVSAKSPKKPRRRVLNSARLGAESRKNPQRRGQKSMAAKSRVGSG 315
             VS  + + P+ +       G  SR+ P+   Q S+AA    G+G
Sbjct: 1586 KVSG-ATRHPQPK-------GHGSRETPRCPAQPSVAASQEAGNG 1622


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 46/187 (24%), Positives = 78/187 (41%), Gaps = 16/187 (8%)

Query: 125 CLSQDASRSGSRVCRSRPQTRGGGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQK 184
           C  +++ R   R  R + +      +K  RG+K      K   G  R R  K+ R + +K
Sbjct: 29  CTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKE-REKQRK 87

Query: 185 AAAAGAKSCGGGGKKPQKARAVGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQGEKGRK 244
                 +      KK ++ +  G R R  KK R+  ++      E+  KK R+   K R+
Sbjct: 88  ERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRK---KKRR 144

Query: 245 KPRRRGQKAAAAGGERCKKPRRQKAAAVSAKSPKKPRRRVLNSARLGAESRKNPQRRGQK 304
           K R+R +       ER K+ R++K      +  K+ R R     +   + R+  +RR +K
Sbjct: 145 KERKREK-------ERGKRERKRKKRKKEEREKKRERNR-----KERKKERERKERRERK 192

Query: 305 SMAAKSR 311
               K R
Sbjct: 193 KERKKER 199



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 42/208 (20%), Positives = 81/208 (38%), Gaps = 19/208 (9%)

Query: 88  QRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRSGPRRCLSQDASRSGSRVCRSRPQTRGG 147
           +R   +    +E+   RG   K+  K     +   R+   ++  R   R    R + +  
Sbjct: 42  EREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEK 101

Query: 148 GGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGKKPQKARAVG 207
             KK  R Q+      K +    R R  K+ R R +K             KK ++     
Sbjct: 102 --KKRERKQRGRRERKKKKERKERERENKQRRERKRKKRR----------KKKRRKERKR 149

Query: 208 ARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQGEKGRKKPRRRGQKAAAAGGERCKKPRRQ 267
            + RG ++ +R+ +K      ++   +  ++ E+ RK+ R R +       ER K+ R++
Sbjct: 150 EKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKK-------ERKKERRKK 202

Query: 268 KAAAVSAKSPKKPRRRVLNSARLGAESR 295
           K      K+ ++   +V    R  A +R
Sbjct: 203 KERKKDRKTDRQTDSQVFRPLRESAFNR 230


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 45/188 (23%), Positives = 77/188 (40%), Gaps = 12/188 (6%)

Query: 135 SRVCRSRPQTRGGGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCG 194
           SR  R R  +RG  G + R   ++ +     RG   RSR   + RRR +  +    +S  
Sbjct: 5   SRHYRKRSASRGRSGSRSR--SRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRS 62

Query: 195 GGGKKPQKARAVGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQ--GEKGRKKPRRRGQK 252
              K+ +++R+   R R  ++ R R +    +     G++ R    G K +K   R   K
Sbjct: 63  RDRKRLRRSRS-RERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSK 121

Query: 253 AAAAGGERCKKPRRQKAAAVSAKSPKKPRRRVLNSARLGAESRKNPQR----RGQKSMAA 308
               GGE  K+ ++ K      +  K+      +  +L  E RK  +R    R ++   A
Sbjct: 122 EKTDGGESSKEKKKDKD---DKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKA 178

Query: 309 KSRVGSGK 316
              +G  K
Sbjct: 179 MENIGELK 186



 Score = 31.6 bits (70), Expect = 0.99
 Identities = 27/133 (20%), Positives = 50/133 (37%), Gaps = 5/133 (3%)

Query: 173 RGGKKIRRRGQKAAAAGAKSCGGGGKKPQKARAVGARRRGWKKLRRRGK-----KAAAAG 227
           R  +  R+R      +G++S        +  R    R R   + RRR +     K  +  
Sbjct: 3   RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRS 62

Query: 228 GEKAGKKLRQQGEKGRKKPRRRGQKAAAAGGERCKKPRRQKAAAVSAKSPKKPRRRVLNS 287
            ++   +  +  E+ R + RRR +           + RR ++++   KS K   R     
Sbjct: 63  RDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKE 122

Query: 288 ARLGAESRKNPQR 300
              G ES K  ++
Sbjct: 123 KTDGGESSKEKKK 135


>gi|57529222 basic helix-loop-helix domain containing, class B, 4
           [Homo sapiens]
          Length = 225

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 30/103 (29%), Positives = 48/103 (46%), Gaps = 3/103 (2%)

Query: 186 AAAGAKSCGGGGKKPQKARAVGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQGEKGRKK 245
           AAA A    G  ++P+ AR  G    G         +A A   E +G++   + +   ++
Sbjct: 20  AAAAAGLAYGAAREPEAARGYGTPGPGGDLPAAPAPRAPAQAAESSGEQSGDEDDAFEQR 79

Query: 246 PRRRGQKAAAAGGERCKKPRRQKAAAVSAKSPKKPRRRVLNSA 288
            RRRG  +AA G  R   PR Q++  +S  + ++ R   LN A
Sbjct: 80  RRRRGPGSAADGRRR---PREQRSLRLSINARERRRMHDLNDA 119


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 43/213 (20%), Positives = 81/213 (38%), Gaps = 20/213 (9%)

Query: 112 PKWESSTRSGPRRCLSQDASRSGSRVCRSRPQTRGGGGKKPRRGQKAATAGAKSRGGGVR 171
           P W+S  R   R   ++   +      R + +      K+ R  ++    G K + G  +
Sbjct: 32  PGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERK 91

Query: 172 SRGGKKIRRRGQKAAAAGA----------KSCGGGGKKPQKARAVGARRRGWKKLRRRGK 221
               ++ +RR +K    G           K  G   K+ ++      R+R  +K R R K
Sbjct: 92  KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151

Query: 222 KAAAAGGEK----------AGKKLRQQGEKGRKKPRRRGQKAAAAGGERCKKPRRQKAAA 271
           +      E+           G+K  ++ EK RK+ ++R +       ER +K RR++   
Sbjct: 152 EEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKE 211

Query: 272 VSAKSPKKPRRRVLNSARLGAESRKNPQRRGQK 304
              K  +K  R+         + R   +R+ +K
Sbjct: 212 RKKKEERKKERQKDRQTNWREKERGKRERKERK 244



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 32/115 (27%), Positives = 51/115 (44%), Gaps = 2/115 (1%)

Query: 197 GKKPQKARAVGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQGEKGRKKPRRRGQKAAAA 256
           GKK +++     RR   K+ R R K+     G+K  K  R++ E+ RKK  RR +K    
Sbjct: 51  GKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKK--RRREKENKE 108

Query: 257 GGERCKKPRRQKAAAVSAKSPKKPRRRVLNSARLGAESRKNPQRRGQKSMAAKSR 311
           G E+ K+ +++K          K R R     R   + R+  +   +K    K R
Sbjct: 109 GEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKER 163



 Score = 31.6 bits (70), Expect = 0.99
 Identities = 32/142 (22%), Positives = 56/142 (39%), Gaps = 19/142 (13%)

Query: 179 RRRGQKAAAAGAKSCGGGGKKPQKARAVGARRRGWKKLRRRGKKAAAAGGEKAGK----- 233
           R R  +    G K      KK ++ R    R R  ++ R RGKK      +K  +     
Sbjct: 41  REREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKR 100

Query: 234 ---KLRQQGEKGR---KKPRRRGQKAAAAGGERCKKPRRQKAAAVSAKSPKKPRRRVLNS 287
              K  ++GE+     KK ++   + +  G ER +K  R++      +  K+ R +    
Sbjct: 101 RREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK---- 156

Query: 288 ARLGAESRKNPQRRGQKSMAAK 309
                  RK  ++R +K +  K
Sbjct: 157 ----ERERKERKKRERKQVGEK 174


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.129    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,083,463
Number of Sequences: 37866
Number of extensions: 732797
Number of successful extensions: 7145
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 151
Number of HSP's successfully gapped in prelim test: 543
Number of HSP's that attempted gapping in prelim test: 4640
Number of HSP's gapped (non-prelim): 1753
length of query: 321
length of database: 18,247,518
effective HSP length: 102
effective length of query: 219
effective length of database: 14,385,186
effective search space: 3150355734
effective search space used: 3150355734
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.