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Search of human proteins with 239756957
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
(4470 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 8916 0.0
gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 8792 0.0
gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 8791 0.0
gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sap... 5761 0.0
gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens] 5330 0.0
gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens] 2290 0.0
gi|75677365 dynein heavy chain domain 3 [Homo sapiens] 2194 0.0
gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens] 2027 0.0
gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens] 2019 0.0
gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens] 1980 0.0
gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens] 1950 0.0
gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens] 1938 0.0
gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens] 1926 0.0
gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens] 1368 0.0
gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sap... 1236 0.0
gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens] 1186 0.0
gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens] 976 0.0
gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [H... 718 0.0
gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens] 176 6e-43
gi|71061468 centromere protein E [Homo sapiens] 48 2e-04
gi|124249396 coiled-coil domain containing 30 [Homo sapiens] 46 0.001
gi|34577114 cytomatrix protein p110 [Homo sapiens] 44 0.004
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 42 0.014
gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 42 0.014
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 41 0.023
gi|4502395 beclin 1 [Homo sapiens] 41 0.030
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 41 0.030
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 41 0.030
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 41 0.030
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 41 0.030
>gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4470
Score = 8916 bits (23135), Expect = 0.0
Identities = 4470/4470 (100%), Positives = 4470/4470 (100%)
Query: 1 MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG 60
MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG
Sbjct: 1 MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG 60
Query: 61 MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL 120
MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL
Sbjct: 61 MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL 120
Query: 121 LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER 180
LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER
Sbjct: 121 LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER 180
Query: 181 IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKC 240
IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKC
Sbjct: 181 IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKC 240
Query: 241 IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME 300
IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME
Sbjct: 241 IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME 300
Query: 301 QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK 360
QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK
Sbjct: 301 QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK 360
Query: 361 GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF 420
GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF
Sbjct: 361 GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF 420
Query: 421 FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD 480
FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD
Sbjct: 421 FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD 480
Query: 481 PGDSVGPRAGLDELDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMC 540
PGDSVGPRAGLDELDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMC
Sbjct: 481 PGDSVGPRAGLDELDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMC 540
Query: 541 GGLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQ 600
GGLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQ
Sbjct: 541 GGLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQ 600
Query: 601 LKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGV 660
LKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGV
Sbjct: 601 LKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGV 660
Query: 661 DQDCHFNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENE 720
DQDCHFNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENE
Sbjct: 661 DQDCHFNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENE 720
Query: 721 TFRKFVGNLELIVGWYNEVMKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEV 780
TFRKFVGNLELIVGWYNEVMKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEV
Sbjct: 721 TFRKFVGNLELIVGWYNEVMKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEV 780
Query: 781 REILHNLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRYAA 840
REILHNLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRYAA
Sbjct: 781 REILHNLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRYAA 840
Query: 841 VRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNMVI 900
VRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNMVI
Sbjct: 841 VRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNMVI 900
Query: 901 DESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDRMN 960
DESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDRMN
Sbjct: 901 DESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDRMN 960
Query: 961 YKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCA 1020
YKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCA
Sbjct: 961 YKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCA 1020
Query: 1021 VTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQ 1080
VTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQ
Sbjct: 1021 VTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQ 1080
Query: 1081 ALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMK 1140
ALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMK
Sbjct: 1081 ALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMK 1140
Query: 1141 VKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAP 1200
VKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAP
Sbjct: 1141 VKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAP 1200
Query: 1201 LQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKQQKSISAMEGIMEA 1260
LQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKQQKSISAMEGIMEA
Sbjct: 1201 LQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKQQKSISAMEGIMEA 1260
Query: 1261 LSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDI 1320
LSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDI
Sbjct: 1261 LSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDI 1320
Query: 1321 DCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQ 1380
DCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQ
Sbjct: 1321 DCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQ 1380
Query: 1381 VKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPH 1440
VKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPH
Sbjct: 1381 VKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPH 1440
Query: 1441 PRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFE 1500
PRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFE
Sbjct: 1441 PRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFE 1500
Query: 1501 VQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYN 1560
VQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYN
Sbjct: 1501 VQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYN 1560
Query: 1561 KLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFD 1620
KLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFD
Sbjct: 1561 KLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFD 1620
Query: 1621 SLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHE 1680
SLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHE
Sbjct: 1621 SLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHE 1680
Query: 1681 IPEAVVTYEEKPREQWILDYPAQVALTCTQIWWTTEVGLAFARLEEGYENAIRDYNKKQI 1740
IPEAVVTYEEKPREQWILDYPAQVALTCTQIWWTTEVGLAFARLEEGYENAIRDYNKKQI
Sbjct: 1681 IPEAVVTYEEKPREQWILDYPAQVALTCTQIWWTTEVGLAFARLEEGYENAIRDYNKKQI 1740
Query: 1741 SQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIVAKVESSQAFTWQAQLRHRW 1800
SQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIVAKVESSQAFTWQAQLRHRW
Sbjct: 1741 SQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIVAKVESSQAFTWQAQLRHRW 1800
Query: 1801 DEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGT 1860
DEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGT
Sbjct: 1801 DEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGT 1860
Query: 1861 GKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSV 1920
GKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSV
Sbjct: 1861 GKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSV 1920
Query: 1921 IAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCA 1980
IAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCA
Sbjct: 1921 IAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCA 1980
Query: 1981 MVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVA 2040
MVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVA
Sbjct: 1981 MVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVA 2040
Query: 2041 GSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKI 2100
GSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKI
Sbjct: 2041 GSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKI 2100
Query: 2101 IKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRK 2160
IKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRK
Sbjct: 2101 IKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRK 2160
Query: 2161 PVAVDLDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMW 2220
PVAVDLDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMW
Sbjct: 2161 PVAVDLDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMW 2220
Query: 2221 IESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGW 2280
IESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGW
Sbjct: 2221 IESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGW 2280
Query: 2281 NPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLEC 2340
NPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLEC
Sbjct: 2281 NPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLEC 2340
Query: 2341 LLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQ 2400
LLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQ
Sbjct: 2341 LLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQ 2400
Query: 2401 GTIFDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPV 2460
GTIFDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPV
Sbjct: 2401 GTIFDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPV 2460
Query: 2461 MLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGP 2520
MLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGP
Sbjct: 2461 MLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGP 2520
Query: 2521 PGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMN 2580
PGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMN
Sbjct: 2521 PGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMN 2580
Query: 2581 PTSGSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAA 2640
PTSGSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAA
Sbjct: 2581 PTSGSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAA 2640
Query: 2641 ALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERV 2700
ALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERV
Sbjct: 2641 ALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERV 2700
Query: 2701 YGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVTDMA 2760
YGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVTDMA
Sbjct: 2701 YGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVTDMA 2760
Query: 2761 PLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLS 2820
PLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLS
Sbjct: 2761 PLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLS 2820
Query: 2821 RLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVL 2880
RLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVL
Sbjct: 2821 RLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVL 2880
Query: 2881 INDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCF 2940
INDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCF
Sbjct: 2881 INDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCF 2940
Query: 2941 SPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPVIKASISFFMS 3000
SPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPVIKASISFFMS
Sbjct: 2941 SPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPVIKASISFFMS 3000
Query: 3001 YVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKL 3060
YVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKL
Sbjct: 3001 YVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKL 3060
Query: 3061 QSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVIN 3120
QSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVIN
Sbjct: 3061 QSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVIN 3120
Query: 3121 KNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILT 3180
KNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILT
Sbjct: 3121 KNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILT 3180
Query: 3181 APGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIR 3240
APGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIR
Sbjct: 3181 APGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIR 3240
Query: 3241 SKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNAN 3300
SKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNAN
Sbjct: 3241 SKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNAN 3300
Query: 3301 LSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTL 3360
LSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTL
Sbjct: 3301 LSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTL 3360
Query: 3361 CGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVA 3420
CGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVA
Sbjct: 3361 CGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVA 3420
Query: 3421 TWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKSYLD 3480
TWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKSYLD
Sbjct: 3421 TWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKSYLD 3480
Query: 3481 VIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTK 3540
VIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTK
Sbjct: 3481 VIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTK 3540
Query: 3541 YFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVL 3600
YFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVL
Sbjct: 3541 YFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVL 3600
Query: 3601 KELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYR 3660
KELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYR
Sbjct: 3601 KELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYR 3660
Query: 3661 PAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITY 3720
PAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITY
Sbjct: 3661 PAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITY 3720
Query: 3721 SVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQ 3780
SVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQ
Sbjct: 3721 SVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQ 3780
Query: 3781 GWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRC 3840
GWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRC
Sbjct: 3781 GWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRC 3840
Query: 3841 LRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEAL 3900
LRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEAL
Sbjct: 3841 LRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEAL 3900
Query: 3901 GKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQNIHLVARWLGTLDKKLE 3960
GKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQNIHLVARWLGTLDKKLE
Sbjct: 3901 GKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQNIHLVARWLGTLDKKLE 3960
Query: 3961 RYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQD 4020
RYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQD
Sbjct: 3961 RYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQD 4020
Query: 4021 TLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEA 4080
TLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEA
Sbjct: 4021 TLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEA 4080
Query: 4081 NPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNL 4140
NPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNL
Sbjct: 4081 NPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNL 4140
Query: 4141 DYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVS 4200
DYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVS
Sbjct: 4141 DYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVS 4200
Query: 4201 REEKVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKEL 4260
REEKVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKEL
Sbjct: 4201 REEKVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKEL 4260
Query: 4261 NLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTT 4320
NLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTT
Sbjct: 4261 NLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTT 4320
Query: 4321 DFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGS 4380
DFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGS
Sbjct: 4321 DFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGS 4380
Query: 4381 YVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIR 4440
YVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIR
Sbjct: 4381 YVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIR 4440
Query: 4441 GPTYVWTFNLKTKEKAAKWILAAVALLLQV 4470
GPTYVWTFNLKTKEKAAKWILAAVALLLQV
Sbjct: 4441 GPTYVWTFNLKTKEKAAKWILAAVALLLQV 4470
>gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 8792 bits (22813), Expect = 0.0
Identities = 4433/4511 (98%), Positives = 4441/4511 (98%), Gaps = 67/4511 (1%)
Query: 1 MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG 60
MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG
Sbjct: 1 MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG 60
Query: 61 MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL 120
MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL
Sbjct: 61 MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL 120
Query: 121 LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER 180
LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER
Sbjct: 121 LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER 180
Query: 181 IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKC 240
IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKC
Sbjct: 181 IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKC 240
Query: 241 IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME 300
IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME
Sbjct: 241 IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME 300
Query: 301 QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK 360
QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK
Sbjct: 301 QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK 360
Query: 361 GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF 420
GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF
Sbjct: 361 GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF 420
Query: 421 FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD 480
FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD
Sbjct: 421 FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD 480
Query: 481 PGDSVGPRAGLDELDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMC 540
PGDS NFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMC
Sbjct: 481 PGDS------------NFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMC 528
Query: 541 GGLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQ 600
GGLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQ
Sbjct: 529 GGLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQ 588
Query: 601 LKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGV 660
LKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGV
Sbjct: 589 LKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGV 648
Query: 661 DQDCHFNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENE 720
DQDCHFNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENE
Sbjct: 649 DQDCHFNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENE 708
Query: 721 TFRKFVGNLELIVGWYNEV---MKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYI 777
TFRKFVGNLELIVGWYNE+ +KAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYI
Sbjct: 709 TFRKFVGNLELIVGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYI 768
Query: 778 QEVREILHNLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKR 837
QEVREILHNLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKR
Sbjct: 769 QEVREILHNLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKR 828
Query: 838 YAAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDN 897
YAAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDN
Sbjct: 829 YAAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDN 888
Query: 898 MVIDESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKD 957
MVIDESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKD
Sbjct: 889 MVIDESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKD 948
Query: 958 RMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIY 1017
RMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIY
Sbjct: 949 RMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIY 1008
Query: 1018 GCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRP 1077
GCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRP
Sbjct: 1009 GCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRP 1068
Query: 1078 FKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGH 1137
FKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGH
Sbjct: 1069 FKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGH 1128
Query: 1138 LMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLT 1197
LMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLT
Sbjct: 1129 LMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLT 1188
Query: 1198 VAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKQQKSISAMEGI 1257
VAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNK + ++GI
Sbjct: 1189 VAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNK----VFLLKGI 1244
Query: 1258 MEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQ 1317
MEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQ
Sbjct: 1245 MEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQ 1304
Query: 1318 MDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQ 1377
MDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQ
Sbjct: 1305 MDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQ 1364
Query: 1378 ATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQH 1437
ATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQH
Sbjct: 1365 ATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQH 1424
Query: 1438 EPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISI 1497
EPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISI
Sbjct: 1425 EPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISI 1484
Query: 1498 WFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPG 1557
WFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPG
Sbjct: 1485 WFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPG 1544
Query: 1558 LYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSK 1617
LYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSK
Sbjct: 1545 LYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSK 1604
Query: 1618 LFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTL 1677
LFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTL
Sbjct: 1605 LFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTL 1664
Query: 1678 RHEIPEAVVTYEEKPREQWILDYPAQVALTCTQIWWTTEVGLAFARLEEGYENAIRDYNK 1737
RHEIPEAVVTYEEKPREQWILDYPAQ IWWTTEVGLAFARLEEGYENAI+DYNK
Sbjct: 1665 RHEIPEAVVTYEEKPREQWILDYPAQ-------IWWTTEVGLAFARLEEGYENAIKDYNK 1717
Query: 1738 KQISQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIVAKVESSQAFTWQAQLR 1797
KQISQLNVLITLL+GNLNAGDRMKIMTICTIDVHARDVVAKMIV ESSQAFTWQAQLR
Sbjct: 1718 KQISQLNVLITLLIGNLNAGDRMKIMTICTIDVHARDVVAKMIV---ESSQAFTWQAQLR 1774
Query: 1798 HRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGP 1857
HRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGP
Sbjct: 1775 HRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGP 1834
Query: 1858 AGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEV 1917
AGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEV
Sbjct: 1835 AGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEV 1894
Query: 1918 LSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFR 1977
LSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFR
Sbjct: 1895 LSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFR 1954
Query: 1978 PCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVL 2037
PCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVL
Sbjct: 1955 PCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVL 2014
Query: 2038 VVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNF 2097
VVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNF
Sbjct: 2015 VVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNF 2074
Query: 2098 EKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNL 2157
EKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNL
Sbjct: 2075 EKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNL 2134
Query: 2158 KRKPVAVDLDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDID 2217
KRKPVAVDLDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDID
Sbjct: 2135 KRKPVAVDLDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDID 2194
Query: 2218 PMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPAD 2277
PMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPAD
Sbjct: 2195 PMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPAD 2254
Query: 2278 LGWNPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYL 2337
LGWNPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYL
Sbjct: 2255 LGWNPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYL 2314
Query: 2338 LECLLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKF 2397
LECLLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKF
Sbjct: 2315 LECLLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKF 2374
Query: 2398 PSQGTIFDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKS 2457
PSQGTIFDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKS
Sbjct: 2375 PSQGTIFDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKS 2434
Query: 2458 WPVMLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRN 2517
WPVMLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRN
Sbjct: 2435 WPVMLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRN 2494
Query: 2518 YGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVA 2577
YGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVA
Sbjct: 2495 YGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVA 2554
Query: 2578 CMNPTSGSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQL 2637
CMNPTSGSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQL
Sbjct: 2555 CMNPTSGSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQL 2614
Query: 2638 VAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHET 2697
VAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHET
Sbjct: 2615 VAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHET 2674
Query: 2698 ERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVT 2757
ERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVT
Sbjct: 2675 ERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVT 2734
Query: 2758 DMAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQ 2817
DMAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQ
Sbjct: 2735 DMAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQ 2794
Query: 2818 SLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQF 2877
SLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQF
Sbjct: 2795 SLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQF 2854
Query: 2878 LVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVI 2937
LVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVI
Sbjct: 2855 LVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVI 2914
Query: 2938 LCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIP-VIKASIS 2996
LCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIP +KASIS
Sbjct: 2915 LCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEVKASIS 2974
Query: 2997 FFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENG 3056
FFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENG
Sbjct: 2975 FFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENG 3034
Query: 3057 LMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKV 3116
LMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKV
Sbjct: 3035 LMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKV 3094
Query: 3117 EVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAV 3176
EVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAV
Sbjct: 3095 EVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAV 3154
Query: 3177 MILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDP 3236
MILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDP
Sbjct: 3155 MILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDP 3214
Query: 3237 EFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAE 3296
EFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAE
Sbjct: 3215 EFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAE 3274
Query: 3297 LNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQ 3356
LNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQ
Sbjct: 3275 LNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQ 3334
Query: 3357 GVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDD 3416
GVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDD
Sbjct: 3335 GVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDD 3394
Query: 3417 ADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQK 3476
ADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQK
Sbjct: 3395 ADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQK 3454
Query: 3477 SYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLI 3536
SYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLI
Sbjct: 3455 SYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLI 3514
Query: 3537 LHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEF 3596
LHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEF
Sbjct: 3515 LHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEF 3574
Query: 3597 KIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEAR 3656
KIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEAR
Sbjct: 3575 KIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEAR 3634
Query: 3657 ENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTD 3716
ENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTD
Sbjct: 3635 ENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTD 3694
Query: 3717 EITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDF 3776
EITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDF
Sbjct: 3695 EITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDF 3754
Query: 3777 LQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLC 3836
LQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLC
Sbjct: 3755 LQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLC 3814
Query: 3837 MVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKD 3896
MVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKD
Sbjct: 3815 MVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKD 3874
Query: 3897 VEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQ--------NIHLV 3948
VEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQ NIHLV
Sbjct: 3875 VEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVRGGQHCRNIHLV 3934
Query: 3949 ARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHA 4008
ARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHA
Sbjct: 3935 ARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHA 3994
Query: 4009 NLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLT 4068
NLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLT
Sbjct: 3995 NLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLT 4054
Query: 4069 ISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDV 4128
ISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDV
Sbjct: 4055 ISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDV 4114
Query: 4129 LLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQP 4188
LLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQP
Sbjct: 4115 LLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQP 4174
Query: 4189 KETDSGAGTGVSREEK-----------------------------VKAVLDDILEKIPET 4219
KETDSGAGTGVSREEK VKAVLDDILEKIPET
Sbjct: 4175 KETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPET 4234
Query: 4220 FNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLST 4279
FNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLST
Sbjct: 4235 FNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLST 4294
Query: 4280 ALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSF 4339
ALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSF
Sbjct: 4295 ALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSF 4354
Query: 4340 LTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVI 4399
LTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVI
Sbjct: 4355 LTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVI 4414
Query: 4400 AEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKW 4459
AEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKW
Sbjct: 4415 AEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKW 4474
Query: 4460 ILAAVALLLQV 4470
ILAAVALLLQV
Sbjct: 4475 ILAAVALLLQV 4485
>gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 8791 bits (22811), Expect = 0.0
Identities = 4433/4511 (98%), Positives = 4439/4511 (98%), Gaps = 67/4511 (1%)
Query: 1 MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG 60
MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG
Sbjct: 1 MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG 60
Query: 61 MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL 120
MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL
Sbjct: 61 MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL 120
Query: 121 LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER 180
LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER
Sbjct: 121 LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER 180
Query: 181 IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKC 240
IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWD RLLNLKC
Sbjct: 181 IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDTRLLNLKC 240
Query: 241 IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME 300
IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME
Sbjct: 241 IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME 300
Query: 301 QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK 360
QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK
Sbjct: 301 QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK 360
Query: 361 GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF 420
GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF
Sbjct: 361 GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF 420
Query: 421 FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD 480
FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD
Sbjct: 421 FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD 480
Query: 481 PGDSVGPRAGLDELDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMC 540
PGDS NFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMC
Sbjct: 481 PGDS------------NFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMC 528
Query: 541 GGLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQ 600
GGLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQ
Sbjct: 529 GGLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQ 588
Query: 601 LKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGV 660
LKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGV
Sbjct: 589 LKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGV 648
Query: 661 DQDCHFNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENE 720
DQDCHFNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENE
Sbjct: 649 DQDCHFNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENE 708
Query: 721 TFRKFVGNLELIVGWYNEV---MKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYI 777
TFRKFVGNLELIVGWYNE+ +KAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYI
Sbjct: 709 TFRKFVGNLELIVGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYI 768
Query: 778 QEVREILHNLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKR 837
QEVREILHNLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKR
Sbjct: 769 QEVREILHNLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKR 828
Query: 838 YAAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDN 897
YAAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDN
Sbjct: 829 YAAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDN 888
Query: 898 MVIDESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKD 957
MVIDESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKD
Sbjct: 889 MVIDESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKD 948
Query: 958 RMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIY 1017
RMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIY
Sbjct: 949 RMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIY 1008
Query: 1018 GCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRP 1077
GCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRP
Sbjct: 1009 GCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRP 1068
Query: 1078 FKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGH 1137
FKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGH
Sbjct: 1069 FKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGH 1128
Query: 1138 LMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLT 1197
LMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLT
Sbjct: 1129 LMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLT 1188
Query: 1198 VAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKQQKSISAMEGI 1257
VAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNK + ++GI
Sbjct: 1189 VAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNK----VFLLKGI 1244
Query: 1258 MEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQ 1317
MEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQ
Sbjct: 1245 MEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQ 1304
Query: 1318 MDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQ 1377
MDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQ
Sbjct: 1305 MDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQ 1364
Query: 1378 ATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQH 1437
ATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQH
Sbjct: 1365 ATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQH 1424
Query: 1438 EPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISI 1497
EPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISI
Sbjct: 1425 EPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISI 1484
Query: 1498 WFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPG 1557
WFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPG
Sbjct: 1485 WFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPG 1544
Query: 1558 LYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSK 1617
LYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSK
Sbjct: 1545 LYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSK 1604
Query: 1618 LFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTL 1677
LFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTL
Sbjct: 1605 LFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTL 1664
Query: 1678 RHEIPEAVVTYEEKPREQWILDYPAQVALTCTQIWWTTEVGLAFARLEEGYENAIRDYNK 1737
RHEIPEAVVTYEEKPREQWILDYPAQ IWWTTEVGLAFARLEEGYENAIRDYNK
Sbjct: 1665 RHEIPEAVVTYEEKPREQWILDYPAQ-------IWWTTEVGLAFARLEEGYENAIRDYNK 1717
Query: 1738 KQISQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIVAKVESSQAFTWQAQLR 1797
KQISQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIV ESSQAFTWQAQLR
Sbjct: 1718 KQISQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIV---ESSQAFTWQAQLR 1774
Query: 1798 HRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGP 1857
HRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGP
Sbjct: 1775 HRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGP 1834
Query: 1858 AGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEV 1917
AGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEV
Sbjct: 1835 AGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEV 1894
Query: 1918 LSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFR 1977
LSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFR
Sbjct: 1895 LSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFR 1954
Query: 1978 PCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVL 2037
PCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVL
Sbjct: 1955 PCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVL 2014
Query: 2038 VVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNF 2097
VVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNF
Sbjct: 2015 VVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNF 2074
Query: 2098 EKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNL 2157
EKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNL
Sbjct: 2075 EKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNL 2134
Query: 2158 KRKPVAVDLDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDID 2217
KRKPVAVDLDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDID
Sbjct: 2135 KRKPVAVDLDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDID 2194
Query: 2218 PMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPAD 2277
PMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPAD
Sbjct: 2195 PMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPAD 2254
Query: 2278 LGWNPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYL 2337
LGWNPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYL
Sbjct: 2255 LGWNPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYL 2314
Query: 2338 LECLLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKF 2397
LECLLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKF
Sbjct: 2315 LECLLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKF 2374
Query: 2398 PSQGTIFDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKS 2457
PSQGTIFDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKS
Sbjct: 2375 PSQGTIFDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKS 2434
Query: 2458 WPVMLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRN 2517
WPVMLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRN
Sbjct: 2435 WPVMLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRN 2494
Query: 2518 YGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVA 2577
YGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVA
Sbjct: 2495 YGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVA 2554
Query: 2578 CMNPTSGSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQL 2637
CMNPTSGSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQL
Sbjct: 2555 CMNPTSGSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQL 2614
Query: 2638 VAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHET 2697
VAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHET
Sbjct: 2615 VAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHET 2674
Query: 2698 ERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVT 2757
ERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVT
Sbjct: 2675 ERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVT 2734
Query: 2758 DMAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQ 2817
DMAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQ
Sbjct: 2735 DMAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQ 2794
Query: 2818 SLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQF 2877
SLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQF
Sbjct: 2795 SLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQF 2854
Query: 2878 LVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVI 2937
LVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVI
Sbjct: 2855 LVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVI 2914
Query: 2938 LCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIP-VIKASIS 2996
LCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIP +KASIS
Sbjct: 2915 LCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEVKASIS 2974
Query: 2997 FFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENG 3056
FFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENG
Sbjct: 2975 FFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENG 3034
Query: 3057 LMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKV 3116
LMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKV
Sbjct: 3035 LMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKV 3094
Query: 3117 EVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAV 3176
EVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAV
Sbjct: 3095 EVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAV 3154
Query: 3177 MILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDP 3236
MILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDP
Sbjct: 3155 MILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDP 3214
Query: 3237 EFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAE 3296
EFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAE
Sbjct: 3215 EFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAE 3274
Query: 3297 LNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQ 3356
LNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQ
Sbjct: 3275 LNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQ 3334
Query: 3357 GVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDD 3416
GVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDD
Sbjct: 3335 GVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDD 3394
Query: 3417 ADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQK 3476
ADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQK
Sbjct: 3395 ADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQK 3454
Query: 3477 SYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLI 3536
SYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLI
Sbjct: 3455 SYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLI 3514
Query: 3537 LHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEF 3596
LHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEF
Sbjct: 3515 LHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEF 3574
Query: 3597 KIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEAR 3656
KIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEAR
Sbjct: 3575 KIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEAR 3634
Query: 3657 ENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTD 3716
ENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTD
Sbjct: 3635 ENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTD 3694
Query: 3717 EITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDF 3776
EITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDF
Sbjct: 3695 EITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDF 3754
Query: 3777 LQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLC 3836
LQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLC
Sbjct: 3755 LQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLC 3814
Query: 3837 MVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKD 3896
MVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKD
Sbjct: 3815 MVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKD 3874
Query: 3897 VEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQ--------NIHLV 3948
VEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQ NIHLV
Sbjct: 3875 VEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVRGGQHCRNIHLV 3934
Query: 3949 ARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHA 4008
ARWLGTLDKKLE YSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHA
Sbjct: 3935 ARWLGTLDKKLEHYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHA 3994
Query: 4009 NLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLT 4068
NLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLT
Sbjct: 3995 NLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLT 4054
Query: 4069 ISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDV 4128
ISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDV
Sbjct: 4055 ISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDV 4114
Query: 4129 LLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQP 4188
LLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQP
Sbjct: 4115 LLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQP 4174
Query: 4189 KETDSGAGTGVSREEK-----------------------------VKAVLDDILEKIPET 4219
KETDSGAGTGVSREEK VKAVLDDILEKIPET
Sbjct: 4175 KETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPET 4234
Query: 4220 FNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLST 4279
FNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLST
Sbjct: 4235 FNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLST 4294
Query: 4280 ALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSF 4339
ALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSF
Sbjct: 4295 ALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSF 4354
Query: 4340 LTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVI 4399
LTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVI
Sbjct: 4355 LTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVI 4414
Query: 4400 AEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKW 4459
AEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKW
Sbjct: 4415 AEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKW 4474
Query: 4460 ILAAVALLLQV 4470
ILAAVALLLQV
Sbjct: 4475 ILAAVALLLQV 4485
>gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sapiens]
Length = 4486
Score = 5761 bits (14946), Expect = 0.0
Identities = 2821/4485 (62%), Positives = 3523/4485 (78%), Gaps = 40/4485 (0%)
Query: 6 DVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQ----VLVLTLNAAGM 61
D RL L ++ L+ W + G+ E L F + + +LV+ G+
Sbjct: 22 DRRLRLLGTYVAMSLRPAAGAWERCAGSAEAEQLLQAFLGRDAAEGPRPLLVVRPGPRGL 81
Query: 62 II-PCLGF-PQS--LKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVL 117
I P L P+S +K ++F++T E D++R ++ GD+ P++ L A+ EV+
Sbjct: 82 AIRPGLEVGPESGLAGAKALFFLRTGPEPPGPDSFRGAVVCGDLPAAPLEHLAALFSEVV 141
Query: 118 SSLLNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLES 177
+L +N WP ++ ED+ + H L+ ++ V+ ++KGKTLLP+P ++
Sbjct: 142 LPVLANEKNRLNWPHMICEDVRRHAHSLQCDLSVILEQVKGKTLLPLPAGSEKMEFADSK 201
Query: 178 MERIPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLN 237
E + S+D +++AIE+ +I WS+Q++ VL ++S+Q LL G +P P+VE EFW +R +
Sbjct: 202 SETVLDSIDKSVIYAIESAVIKWSYQVQVVLKRESSQPLLQGENPTPKVELEFWKSRYED 261
Query: 238 LKCIHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLE 297
LK I+ QL V + ++L+K +S Y+PA + +Y +V L EA DI ++L PL+ LE
Sbjct: 262 LKYIYNQLRTITVRGMAKLLDKLQSSYFPAFKAMYRDVVAALAEAQDIHVHLIPLQRHLE 321
Query: 298 EMEQADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEE 357
+E A+F + + +L +C IWAT + Y +P R+ V+LQE CN +I+ +LSPE+
Sbjct: 322 ALENAEFPEVKPQLRPLLHVVCLIWATCKSYRSPGRLTVLLQEICNLLIQQASNYLSPED 381
Query: 358 VLKGLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVP-WEFPSSLAFSR 416
+L+ E+EE + + + L Q + N+ +FK+ + V W+F SSL F R
Sbjct: 382 LLRS---EVEESQRKLQVVSDTLSFFKQEFQDRRENLHTYFKENQEVKEWDFQSSLVFVR 438
Query: 417 INSFFQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFA---- 472
++ F ++ +E L KTA++F KL K+E GVRGN L V ++++E E+ ++ +
Sbjct: 439 LDGFLGQLHVVEGLLKTALDFHKLGKVEFSGVRGNALSQQVQQMHEEFQEMYRLLSGSSS 498
Query: 473 DCKYDPLDPGDSVGPRAGLDELDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKS 532
DC Y L D F+ D ++F K++DLDRRL TIF Q FDD ++
Sbjct: 499 DCLY--------------LQSTD--FENDVSEFNQKVEDLDRRLGTIFIQAFDDAPGLEH 542
Query: 533 SAKLLYMCGGLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHK 592
+ KLL + G L+ERPL+ + + +Y V++++F+ +LD +++Y + E +HK
Sbjct: 543 AFKLLDIAGNLLERPLVARDTSDKYLVLIQMFNKDLDAVRMIYSQHVQEEAELGFSPVHK 602
Query: 593 NMPPVAGQLKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKI 652
NMP VAG L+W+ EL++R++ + + HP M AE K QKY++M+ LL + ++
Sbjct: 603 NMPTVAGGLRWAQELRQRIQGPFSNFGRITHPCMESAEGKRMQQKYEDMLSLLEKYETRL 662
Query: 653 YQQWVAGVDQDCHFNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSA 712
Y+ W V + +NL QPL+ RD + I +NF+ L++VL+E+ YL ++ K +P++A
Sbjct: 663 YEDWCRTVSEKSQYNLSQPLLKRDPETKEITINFNPQLISVLKEMSYLEPREMKHMPETA 722
Query: 713 ESLFSENETFRKFVGNLELIVGWYNEVMKA---VEFLLIKSELEAIDVKLLSAETTLFWN 769
++FS + +R+ V NLEL+ WYN+VMK VEF L++ EL+ ID++L +AE TL W
Sbjct: 723 AAMFSSRDFYRQLVANLELMANWYNKVMKTLLEVEFPLVEEELQNIDLRLRAAEETLNWK 782
Query: 770 GEGVFQYIQEVREILHNLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDG 829
EG+ Y+ E+ +H+L+ R+QK K N+E I MK W P+F+ KD K+E+LL LD
Sbjct: 783 TEGICDYVTEITSSIHDLEQRIQKTKDNVEEIQNIMKTW-VTPIFKTKDGKRESLLSLDD 841
Query: 830 RIANLNKRYAAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRK 889
R + K Y ++++G+KI A+V EN LF AD S WK YV ID+++L+ F I
Sbjct: 842 RHDRMEKYYNLIKESGLKIHALVQENLGLFSADPTSNIWKTYVNSIDNLLLNGFFLAIEC 901
Query: 890 SLSFLMDNMVIDESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVAR 949
SL +L++N + P+FE ++ L L F P+LE G GF ++EGL+ I+ +
Sbjct: 902 SLKYLLENTECKAGLTPIFEAQLSLAIPELVFYPSLESGVKGGFCDIVEGLITSIFRIPS 961
Query: 950 LIPRLAKDR--MNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNL 1007
L+PRL+ +Y++DL+ DL MR + V M YQ +F +YSYL+ ++
Sbjct: 962 LVPRLSPQNGSPHYQVDLDGIPDLANMRRTLMERVQRMMGLCCGYQSTFSQYSYLYVEDR 1021
Query: 1008 QEFMKNFLIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVF 1067
+E + FL+YG +T E+++ +D IP+ PP L+QF+ QIDSYE LYEEV + E KVF
Sbjct: 1022 KEVLGQFLLYGHILTPEEIEDHVEDGIPENPPLLSQFKVQIDSYETLYEEVCRLEPIKVF 1081
Query: 1068 HGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGD 1127
GW++ D RPFK +LL+ I+RW +FK+HL +HVT+SLA+L+AF+K + GL K +++GD
Sbjct: 1082 DGWMKIDIRPFKASLLNIIKRWSLLFKQHLVDHVTHSLANLDAFIKKSESGLLKKVEKGD 1141
Query: 1128 YDGLVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANT 1187
+ GLVE+MGHLM VKERQ+ TD MFEPLKQTIELLKTY +E+PE + +L+ELPE W N
Sbjct: 1142 FQGLVEIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELPETVFKQLEELPEKWNNI 1201
Query: 1188 KKLAIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKQ 1247
KK+AI VK VAPLQANEV++LR++C F+ +Q +F E+F +EAPF F +P++ L+ +
Sbjct: 1202 KKVAITVKQQVAPLQANEVTLLRQRCTAFDAEQQQFWEQFHKEAPFRFDSIHPHQMLDAR 1261
Query: 1248 QKSISAMEGIMEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKT 1307
I ME M ++S+S LFEV VPDYKQL+ C +EV LKELWD + +V +SI W+T
Sbjct: 1262 HIEIQQMESTMASISESASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWET 1321
Query: 1308 TKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAI 1367
T W++INVE M+++CK+FA+ +R+LDKE++ WDAF GL++TV N ++SLRAV+ELQNPAI
Sbjct: 1322 TPWRNINVEAMELECKQFARHIRNLDKEVRAWDAFTGLESTVWNTLSSLRAVAELQNPAI 1381
Query: 1368 RERHWQQLMQATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALD 1427
RERHW+QLMQAT V F M ++TTLA LLQL LH YEDEVR IVDKA KE GMEK LK L
Sbjct: 1382 RERHWRQLMQATGVSFTMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKELQ 1441
Query: 1428 STWSMMEFQHEPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQK 1487
+TW+ MEFQ+EPHPRT +L S E L+E LEDNQVQLQNL+MSKY+A FL+EV+ WQ+K
Sbjct: 1442 TTWAGMEFQYEPHPRTNVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQKK 1501
Query: 1488 LSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTP 1547
LST D+VISIWFEVQRTW+HLESIF GSEDIR QLP DS+RF+ I+ +FK L DA K P
Sbjct: 1502 LSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQKIP 1561
Query: 1548 NVVEATSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGND 1607
NVV+ T+KPGLY KLE ++ L +CEKALAEYL+TKRLAFPRFYF+SS+DLLDILSNG
Sbjct: 1562 NVVQTTNKPGLYEKLEDIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGTA 1621
Query: 1608 PVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLN 1667
P +V RHLSKLFD++ K++F+LDAS +P K LGMYSKE+EY+ F + CD SGQVE+WLN
Sbjct: 1622 PQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKEEEYVAFSEPCDCSGQVEIWLN 1681
Query: 1668 RVLDRMCSTLRHEIPEAVVTYEEKPREQWILDYPAQVALTCTQIWWTTEVGLAFARLEEG 1727
VL M +T+RHE+ E V YEEKPREQW+ D+PAQVALTCTQIWWTTEVG+AFARLEEG
Sbjct: 1682 HVLGHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVGMAFARLEEG 1741
Query: 1728 YENAIRDYNKKQISQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIVAKVESS 1787
YE+A++DY KKQ++QL LIT+L+G L+ GDR KIMTICTIDVHARDVVAKMI KV+++
Sbjct: 1742 YESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDNA 1801
Query: 1788 QAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLH 1847
QAF W +QLRHRWD+E +HCFANICDAQ YSYEYLGNTPRLVITPLTDRCYITLTQSLH
Sbjct: 1802 QAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLH 1861
Query: 1848 LIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCF 1907
L M GAPAGPAGTGKTETTKDLGRALG +VYVFNCSEQMDYKSCGNIYKGLAQTGAWGCF
Sbjct: 1862 LTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCF 1921
Query: 1908 DEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAE 1967
DEFNRISVEVLSV+AVQVK +QDAIR KK+ F+FLGE I L P+VGIFITMNPGYAGR E
Sbjct: 1922 DEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGRTE 1981
Query: 1968 LPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYD 2027
LPENLK+LFRPCAMVVPDFELICEIML+AEGF+EA+ LARKFITLY LCKELLSKQDHYD
Sbjct: 1982 LPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYD 2041
Query: 2028 WGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPAL 2087
WGLRAIKSVLVVAGSLKRGDP R EDQVLMR+LRDFNIPKIVTDD+P+FMGLIGDLFPAL
Sbjct: 2042 WGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPAL 2101
Query: 2088 DVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVL 2147
DVPR+RD NFE +++++IV+LKLQAED+FVLKVVQLEELL VRHSVF+VG AG+GKSQVL
Sbjct: 2102 DVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQVL 2161
Query: 2148 KSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGP 2207
+SL+KTYQ +KR+PV DL+PKAVT DELFGIINP T EWKDGLFS+IMR+LANITHDGP
Sbjct: 2162 RSLHKTYQIMKRRPVWTDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANITHDGP 2221
Query: 2208 KWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSR 2267
KWI+LDGDIDPMWIESLNTVMDDNKVLTLASNERIPLN TM+L+FEISHLRTATPATVSR
Sbjct: 2222 KWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPATVSR 2281
Query: 2268 AGILYINPADLGWNPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPE 2327
AGILYINPADLGWNP VSSWIE+R++Q+E+ANL ILFDKYLPTCLD LR FKKI P+PE
Sbjct: 2282 AGILYINPADLGWNPPVSSWIEKREIQTERANLTILFDKYLPTCLDTLRTRFKKIIPIPE 2341
Query: 2328 ITVIQTILYLLECLLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKW 2387
+++Q + +LLECLLT + +P D P+E+YE YFVF WAFGGAM QDQLVDYR EFSKW
Sbjct: 2342 QSMVQMVCHLLECLLTTEDIPADCPKEIYEHYFVFAAIWAFGGAMVQDQLVDYRAEFSKW 2401
Query: 2388 WINEFKTIKFPSQGTIFDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIR 2447
W+ EFKT+KFPSQGTIFDYYIDP+TKKF PW+ VP FE DP++PLQA LVHT+ETIR+
Sbjct: 2402 WLTEFKTVKFPSQGTIFDYYIDPETKKFEPWSKLVPQFEFDPEMPLQACLVHTSETIRVC 2461
Query: 2448 YFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLE 2507
YFM+ LM + PVMLVG AGTGKSVL+G KL SL+ + YLV+ VPFN+YTTSAMLQ VLE
Sbjct: 2462 YFMERLMARQRPVMLVGTAGTGKSVLVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVLE 2521
Query: 2508 KPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTL 2567
KPLEKK+GRNYGPPG KKL+YFIDDMNMPEVD YGTV PHT+IRQH+D+ HWYDR KL+L
Sbjct: 2522 KPLEKKAGRNYGPPGNKKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKLSL 2581
Query: 2568 KDIHNCQYVACMNPTSGSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVS 2627
K+I N QYV+CMNPT+GSFTI+ RLQRHF VF +SFPG +AL++IY+ ILTQHL +
Sbjct: 2582 KEITNVQYVSCMNPTAGSFTINPRLQRHFSVFVLSFPGADALSSIYSIILTQHLKLGNFP 2641
Query: 2628 MAIQRISSQLVAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPL 2687
++Q+ L+ ALA HQKI TFLPT IKFHY+FNLRD +NIFQG+LFS+ E +K+
Sbjct: 2642 ASLQKSIPPLIDLALAFHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKSTW 2701
Query: 2688 DLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDEL-LFAKPNIFCHFAQ 2746
DL+RL+LHE+ RVY DKMV+EKD + ++ KK FDD+ D + PN++CHFA
Sbjct: 2702 DLIRLYLHESNRVYRDKMVEEKDFDLFDKIQTEVLKKTFDDIEDPVEQTQSPNLYCHFAN 2761
Query: 2747 GIGDPKYVPVTDMAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNA 2806
GIG+PKY+PV L + LV+ L+++NEVN VM+LVLFEDA+ H+C INRILESPRGNA
Sbjct: 2762 GIGEPKYMPVQSWELLTQTLVEALENHNEVNTVMDLVLFEDAMRHVCHINRILESPRGNA 2821
Query: 2807 LLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFL 2866
LLVGVGGSGKQSL+RLAA+IS +DVFQITL+KGY I D K+DLA+ +KA VKN+ +VFL
Sbjct: 2822 LLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFL 2881
Query: 2867 MTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFF 2926
MTD+QVA+E+FLVLINDLLASGEIP L+ +DEVENIIS++R +VKS G+ D RE CWKFF
Sbjct: 2882 MTDAQVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQGLVDNRENCWKFF 2941
Query: 2927 IEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETE 2986
I+++RRQLKV LCFSPVG+ LRVR+RKFPA+VNCTAI WFHEWP+ AL SVS RFL+ TE
Sbjct: 2942 IDRIRRQLKVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTE 3001
Query: 2987 GI-PVIKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTE 3045
GI P +K SIS FM++VHT+VN+ S+ YL+ E+RYNYTTPK+FLE I+LYQ+LL + R E
Sbjct: 3002 GIEPTVKQSISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKE 3061
Query: 3046 LVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKE 3105
L K ERLENGL+KL ST++QVDDLKAKLA QE ELKQKNE AD+LIQVVG+E +KVS+E
Sbjct: 3062 LKCKTERLENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSRE 3121
Query: 3106 KAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSP 3165
KA+AD+EE KV VI V +KQK CE DLAKAEPAL AAQ AL+TLNK NLTELKSFGSP
Sbjct: 3122 KAMADEEEQKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSP 3181
Query: 3166 PDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAF 3225
P AV NV+AAVM+L AP G++PKD+SWKAAK+ M KVD FLDSL F+KE+I E CLKA
Sbjct: 3182 PLAVSNVSAAVMVLMAPRGRVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAI 3241
Query: 3226 KPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQE 3285
+PY +P F+PEF+ +KS AAAGLCSW INIVRFYEV+CDV PKRQAL +A A+L AQE
Sbjct: 3242 RPYLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQE 3301
Query: 3286 KLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIR 3345
KL+ IK KIA LN NL+ LT+ FEKATA+K+KCQQEA+ T I LANRLVGGLASEN+R
Sbjct: 3302 KLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASENVR 3361
Query: 3346 WAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITN 3405
WA++V+NF+ Q TLCGD+LLI+AF+SY+G+FTKKYR L+++ W PY+ LK PIP+T
Sbjct: 3362 WADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVTP 3421
Query: 3406 GLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYR 3465
LDPL +L DDADVA W N+GLP+DRMS ENATIL N ERWPL+VD QLQGIKWIKNKY
Sbjct: 3422 ALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQGIKWIKNKYG 3481
Query: 3466 SELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDK 3525
+L+ ++GQK YL +IEQA+ G +LIEN+ E++DPVL PLLGR IKKG++IKIGDK
Sbjct: 3482 EDLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKGRFIKIGDK 3541
Query: 3526 EVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQL 3585
E EY+PKFRLILHTK NPHY+PE+QAQ TLINF VTRDGLEDQLLAAVV+ ERPDLEQL
Sbjct: 3542 ECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQL 3601
Query: 3586 KANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEA 3645
K++LTK QN FKI LK LEDSLL+RLS+ASGNFLG+T LVENLE TK TA+E+E+KV EA
Sbjct: 3602 KSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQEA 3661
Query: 3646 KITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPAN 3705
K+TEVKINEARE+YRPAA RASLLYFI+NDL+KI+P+YQFSLKAF++VF+KA++R P
Sbjct: 3662 KVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDE 3721
Query: 3706 EVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFP 3765
+++RV NL D IT+SVY YT RGLFE DKL +LAQ+TFQ+L M +E+N VELDFLLR P
Sbjct: 3722 SLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAVELDFLLRSP 3781
Query: 3766 FKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKE 3825
+ G SPV+FL HQ WG +K LS M+EF NLD DIEGSAK WKK VESE PEKE P+E
Sbjct: 3782 VQTGTASPVEFLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQE 3841
Query: 3826 WKNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFF 3885
WKNKTALQ+LCM+R +RPDRMTYA+++FVEEK+GSK+V GR+++F+ S+EES P+T +FF
Sbjct: 3842 WKNKTALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFF 3901
Query: 3886 ILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQNI 3945
ILSPGVDPLKDVE+ G+KLG+T +N HNVSLGQGQEVVAE ALD+AA+KGHWVILQNI
Sbjct: 3902 ILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNI 3961
Query: 3946 HLVARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTG 4005
HLVA+WL TL+KKLE +S SH ++RVF+SAEPAPSPE HIIPQGILEN+IKITNEPPTG
Sbjct: 3962 HLVAKWLSTLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTG 4021
Query: 4006 MHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNG 4065
MHANLHKALD FTQDTLEMC++E EFK +LFALCYFHAVVAERRKFG QGWNRSYPFN G
Sbjct: 4022 MHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTG 4081
Query: 4066 DLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLE 4125
DLTIS+NVLYN+LEAN KVP+DDLRYLFGEIMYGGHITDDWDRRLCRTYL E+IR EMLE
Sbjct: 4082 DLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLE 4141
Query: 4126 GDVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLE 4185
G++ LAPGF +P N+DY GYH+YID LPPESPYLYGLHPNAEIGFLT TSEKLFRTVLE
Sbjct: 4142 GELSLAPGFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLE 4201
Query: 4186 MQPKETDSGAGTGVSREEKVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECER 4245
+QP+++ + G G +REEKVKA+L++ILE++ + FN+ E+MAK E+TPY+VVAFQEC R
Sbjct: 4202 LQPRDSQARDGAGATREEKVKALLEEILERVTDEFNIPELMAKVEERTPYIVVAFQECGR 4261
Query: 4246 MNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWY 4305
MNILT E++RSL+EL LGLKGELT+T+ +E+L AL++D VP++W RAYPS GLAAW+
Sbjct: 4262 MNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWF 4321
Query: 4306 ADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVT 4365
DLL RI+ELEAWT DF +P+TVWL GFFNPQSFLTAIMQS ARKNEWPLD+M L ++T
Sbjct: 4322 PDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDMT 4381
Query: 4366 KKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRME 4425
KKNRE+ +PPREG+Y++GLFMEGA WDTQ G+I EA+LK+LTP MPV+FIKAIP D+ +
Sbjct: 4382 KKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQD 4441
Query: 4426 TKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKWILAAVALLLQV 4470
+++Y CPVYKT RGPTYVWTFNLKTKE +KW+LA VALLLQ+
Sbjct: 4442 CRSVYSCPVYKTSQRGPTYVWTFNLKTKENPSKWVLAGVALLLQI 4486
>gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]
Length = 4523
Score = 5330 bits (13827), Expect = 0.0
Identities = 2627/4491 (58%), Positives = 3377/4491 (75%), Gaps = 43/4491 (0%)
Query: 2 TMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAGM 61
+ A D R+ +L +++L F +KWS+ + +E+N + EF E LV + A+G
Sbjct: 52 SFAQDARVRFLGGRLAMMLGFTEEKWSQYLESEDNRQVLGEFLESTSPACLVFSFAASGR 111
Query: 62 IIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSLL 121
+ P+ K V+ K +E+I +++ +L+G++ + + A ++E+L +L
Sbjct: 112 LAASQEIPRDANHKLVFISKKITESIGVNDFSQVVLFGELPALSLGHVSAFLDEILVPVL 171
Query: 122 NQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMERI 181
+ N W S+D+ + +K +M++ GK+ +TLLPIP G +D E
Sbjct: 172 SNKNNHKSWSCFTSQDMEYHIEVMKKKMYIFRGKMSRRTLLPIPTVAGKMDLDQNCSENK 231
Query: 182 PSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKCI 241
P S + ++LHAIE+ +I+WSHQI++++ +DS Q LL+GLH PQ E +FW R NL CI
Sbjct: 232 PPSNERIILHAIESVVIEWSHQIQEIIERDSVQRLLNGLHLSPQAELDFWMMRRENLSCI 291
Query: 242 HEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEMEQ 301
++QL P V K+V+IL +S Y+P L++++ V L EA D+ LYL+PLR ++ +++
Sbjct: 292 YDQLQAPVVLKMVKILTTKQSSYFPTLKDIFLAVENALLEAQDVELYLRPLRRHIQCLQE 351
Query: 302 ADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLKG 361
+F IA + TIC IW+ S++YNTPAR+IV+LQEFCN I +LSPE++L+G
Sbjct: 352 TEFPQTRILIAPLFHTICLIWSHSKFYNTPARVIVLLQEFCNLFINQATAYLSPEDLLRG 411
Query: 362 LQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSFF 421
EIEE L + +AVN+LK ++ + +F ++ PW+F S L F R + F
Sbjct: 412 ---EIEESLEKVQVAVNILKTFKNSFFNYRKKLASYFMGRKLRPWDFQSHLVFCRFDKFL 468
Query: 422 QRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLDP 481
R+ IE+++ T +EF KLE++E GG +G +L V + +E+ EL K+F YDP D
Sbjct: 469 DRLIKIEDIFATTLEFEKLERLEFGGTKGAILNGQVHEMSEELMELCKLFKQSTYDPSDC 528
Query: 482 GDSVGPRAGLDELDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCG 541
+ F+ DY F+ K + DRRL TI C+ F +C+ ++++ KLL + G
Sbjct: 529 ------------TNMEFESDYVAFKSKTLEFDRRLGTIICEAFFNCNGLEAAFKLLTIFG 576
Query: 542 GLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQL 601
+E+P+++ + YS ++ +F+ ELD K LY+ M E G++ +++KNMP +G +
Sbjct: 577 NFLEKPVVMEIFSLHYSTLVHMFNTELDVCKQLYNEHMKQIECGHV-VLNKNMPFTSGNM 635
Query: 602 KWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVD 661
KW+ ++ +RL++ + + + + + L YQKY EM LL +IY +W + VD
Sbjct: 636 KWAQQVLQRLQMFWSNFASLRYLFLGNPDHALVYQKYVEMTTLLDQFESRIYNEWKSNVD 695
Query: 662 QDCHFNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENET 721
+ C FNL QPL+ A + L+ VNF LVAVLREVKYL ++++IPDSA ++F + T
Sbjct: 696 EICEFNLNQPLVKFSAINGLLCVNFDPKLVAVLREVKYLLMLKKQDIPDSALAIFKKRNT 755
Query: 722 FRKFVGNLELIVGWYNEVMKA---VEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQ 778
K++GNL+L+V YN++ + VE+ LI+ EL AID +L +A T L W + + YI+
Sbjct: 756 ILKYIGNLDLLVQGYNKLKQTLLEVEYPLIEDELRAIDEQLTAATTWLTWQDD-CWGYIE 814
Query: 779 EVREILHNLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRY 838
VR L++R+++ ++N++ I Q M+ W+ L R+++++EA L+ + K+Y
Sbjct: 815 RVRAATSELEHRVERTQKNVKVIQQTMRGWARCVLPPRREHRREAAFTLEDKGDLFTKKY 874
Query: 839 AAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNM 898
++ G KI +V EN +LF+A+ WK YV +IDD+V++ F Q I L F + N
Sbjct: 875 KLIQGDGCKIHNLVEENRKLFKANPSLDTWKIYVEFIDDIVVEGFFQAIMHDLDFFLKNT 934
Query: 899 VIDESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAK-- 956
AP F+ +M L + F P+L+ + GF L+E ++ + + ++ + R+A
Sbjct: 935 EKQLKPAPFFQAQMILLPPEIVFKPSLDREAGDGFYDLVEEMLCNSFRMSAQMNRIATHL 994
Query: 957 DRMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLI 1016
+ NY+ D+++ L E+R+E+ + V+N + + +++++ E ++YLW D+ EFMK+FL+
Sbjct: 995 EIKNYQNDMDNMLGLAEVRQEIMNRVVNVINKVLDFRNTLETHTYLWVDDRAEFMKHFLL 1054
Query: 1017 YGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCR 1076
YG AV+++++D ++ IP+ PPTL QF+EQID YE LY ++SK E+ +VF W + D +
Sbjct: 1055 YGHAVSSDEMDAHANEEIPEQPPTLEQFKEQIDIYEALYVQMSKFEDFRVFDSWFKVDMK 1114
Query: 1077 PFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMG 1136
PFK +LL+ I++W +MF+ HL V +SL +L+ F+K GL + L EGD+DGLV++M
Sbjct: 1115 PFKVSLLTIIKKWSWMFQEHLLRFVIDSLNELQEFIKETDSGLQRELNEGDHDGLVDIMV 1174
Query: 1137 HLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKL 1196
HL+ V+ RQ ATD +FEPLK+TI LL++YG++MPE+++++L+ELPE W TKK+A V+
Sbjct: 1175 HLLAVRSRQRATDELFEPLKETITLLESYGQKMPEQVYIQLEELPERWETTKKIAATVRH 1234
Query: 1197 TVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKQQKSISAMEG 1256
V+PL EV+++R+KC F+ KQ EFRERFR AP F+ NPY +L+K + + A+E
Sbjct: 1235 EVSPLHNAEVTLIRKKCILFDAKQAEFRERFRHYAPLGFNAENPYTALDKANEELEALEE 1294
Query: 1257 IMEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVE 1316
M + +S LFEV +P+YKQ+K C +E++LLK LWD+++ V SI++W T+W+ I+VE
Sbjct: 1295 EMLQMQESTRLFEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTKTQWRQIHVE 1354
Query: 1317 QMDIDCKKFAK-----DMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERH 1371
QMD++ ++FAK ++ SL+KE++ WDA+ GL+ TVK++ SLRA++ELQ+PA+R+RH
Sbjct: 1355 QMDVELRRFAKASSITEIWSLNKEVRVWDAYTGLEGTVKDMTASLRAITELQSPALRDRH 1414
Query: 1372 WQQLMQATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWS 1431
W QLM+A VKF ++E TTLADLL L LH ED+VR IVDKAVKE G EKV+ + TW+
Sbjct: 1415 WHQLMKAIGVKFLINEATTLADLLALRLHRVEDDVRRIVDKAVKELGTEKVITEISQTWA 1474
Query: 1432 MMEFQHEPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTA 1491
M+F +E H RTG +LKS E L ETLE NQVQLQ L+ SKY+ +F+++V SWQ KL+ A
Sbjct: 1475 TMKFSYEVHYRTGIPLLKSDEQLFETLEHNQVQLQTLLQSKYVEYFIEQVLSWQNKLNIA 1534
Query: 1492 DSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVE 1551
D VI W EVQRTWSHLESIF+ SEDIR QL D++RFD ++ EFK LM K NV+E
Sbjct: 1535 DLVIFTWMEVQRTWSHLESIFVCSEDIRIQLVKDARRFDGVDAEFKELMFKTAKVENVLE 1594
Query: 1552 ATSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEV 1611
AT +P LY KL+ L+ L++CEKALAEYLETKR+AFPRFYFVSSADLLDILS G P +V
Sbjct: 1595 ATCRPNLYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFYFVSSADLLDILSKGAQPKQV 1654
Query: 1612 SRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLD 1671
+ HL+KLFDS+ L+F D D +GMYSKE EY+ F EC+ G VE WL ++
Sbjct: 1655 TCHLAKLFDSIADLQFE-DNQDVSAHRAVGMYSKEKEYVPFQAECECVGHVETWLLQLEQ 1713
Query: 1672 RMCSTLRHEIPEAVVTYEEKPREQWILDYPAQVALTCTQIWWTTEVGLAFARLEEGYENA 1731
M T+RH I EA+V YEEKPRE WI D+PAQVALT +QIWWTT+VG+AF+RLEEGYE A
Sbjct: 1714 TMQETVRHSITEAIVAYEEKPRELWIFDFPAQVALTSSQIWWTTDVGIAFSRLEEGYETA 1773
Query: 1732 IRDYNKKQISQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIVAK--VESSQA 1789
++D++KKQISQLN LITLL+G L GDR KIMTICTIDVHARDVVAK+I K V S QA
Sbjct: 1774 LKDFHKKQISQLNTLITLLLGELPPGDRQKIMTICTIDVHARDVVAKLISQKQVVVSPQA 1833
Query: 1790 FTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLI 1849
FTW +QLRHRW++ ++HCF NICDAQ QY YEYLGN+PRLVITPLTDRCYITLTQSLHL
Sbjct: 1834 FTWLSQLRHRWEDTQKHCFVNICDAQFQYFYEYLGNSPRLVITPLTDRCYITLTQSLHLT 1893
Query: 1850 MGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDE 1909
M GAPAGPAGTGKTETTKDLGRALG MVYVFNCSEQMDYKS GNIYKGL QTGAWGCFDE
Sbjct: 1894 MSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGAWGCFDE 1953
Query: 1910 FNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELP 1969
FNRISVEVLSV+AVQVK + DAIR +KK F FLGE I L P+VGIFITMNPGYAGR ELP
Sbjct: 1954 FNRISVEVLSVVAVQVKMIHDAIRNRKKRFVFLGEAITLKPSVGIFITMNPGYAGRTELP 2013
Query: 1970 ENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWG 2029
ENLKALFRPCAMV PD ELICEI+L+AEGF++AR LARKFITLYTLCKELLSKQDHYDWG
Sbjct: 2014 ENLKALFRPCAMVAPDIELICEILLVAEGFVDARALARKFITLYTLCKELLSKQDHYDWG 2073
Query: 2030 LRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDV 2089
LRAIKSVLVVAGSLKRGD +R EDQVLMRALRDFN+PKIVTDD+PVF+GL+GDLFPALDV
Sbjct: 2074 LRAIKSVLVVAGSLKRGDKNRPEDQVLMRALRDFNMPKIVTDDIPVFLGLVGDLFPALDV 2133
Query: 2090 PRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKS 2149
PR+R L+FE++++QS +EL+LQ E+SF+LKVVQLEELL VRHSVF+VGNAG+GKS++L++
Sbjct: 2134 PRRRKLHFEQMVRQSTLELRLQPEESFILKVVQLEELLAVRHSVFVVGNAGTGKSKILRT 2193
Query: 2150 LNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPVTREWKDG---------LFSTIMRDLA 2200
LN+TY N+K+KPV DL+PKAVT DELFG I+ TREWKDG LFS+I+R+ A
Sbjct: 2194 LNRTYVNMKQKPVWNDLNPKAVTTDELFGFIHHATREWKDGKIVYSYFIGLFSSILREQA 2253
Query: 2201 NITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTA 2260
N+ HDGPKWI+LDGDIDPMWIESLNTVMDDNKVLTLASNERI L MRL+FEI HLR+A
Sbjct: 2254 NLKHDGPKWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIALTPFMRLLFEIHHLRSA 2313
Query: 2261 TPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFK 2320
TPATVSRAGILY+NP DLGWNP V+SWI+RR+ QSEKANL ILFDKY+P CLDKLR FK
Sbjct: 2314 TPATVSRAGILYVNPQDLGWNPYVASWIDRRRHQSEKANLTILFDKYVPACLDKLRTSFK 2373
Query: 2321 KITPVPEITVIQTILYLLECLLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDY 2380
IT +PE +++QT+ LLECLLT + VP DSP+E+YE+YFVF C WAFGG + QDQ+ DY
Sbjct: 2374 TITSIPESSLVQTLCVLLECLLTPENVPSDSPKEVYEVYFVFACIWAFGGTLLQDQISDY 2433
Query: 2381 RVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHT 2440
+ +FS+WW E K +KFPSQGTIFDYY+D TKK LPW DK+ F +DPDVPLQ LVHT
Sbjct: 2434 QADFSRWWQKEMKAVKFPSQGTIFDYYVDHKTKKLLPWADKIAQFTMDPDVPLQTVLVHT 2493
Query: 2441 TETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSA 2500
TET R+RYFM+LL+EK P+MLVGNAG GK+V +GD L SL+ D Y+V VPFN+YTTS
Sbjct: 2494 TETARLRYFMELLLEKGKPLMLVGNAGVGKTVFVGDTLASLSED-YIVSRVPFNYYTTST 2552
Query: 2501 MLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWY 2560
LQ +LEKPLEKK+G NYGP G KKL+YFIDDMNMPEVD YGTV PHTLIRQH+D+ HWY
Sbjct: 2553 ALQKILEKPLEKKAGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWY 2612
Query: 2561 DRHKLTLKDIHNCQYVACMNPTSGSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQH 2620
DR K+ LK+IHNCQYVACMNP GSFTI+ RLQRHF VFA +FP +AL TIY I + H
Sbjct: 2613 DRQKVMLKEIHNCQYVACMNPMVGSFTINPRLQRHFTVFAFNFPSLDALNTIYGQIFSFH 2672
Query: 2621 LAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTA 2680
++ + +I R L+ A +A HQ + FLPTAIKFHY+FNLRDLSN+FQG+LF++
Sbjct: 2673 FQQQAFAPSILRSGPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFASP 2732
Query: 2681 EVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNI 2740
E LK PLDL+ LWLHE+ RVYGDK++D+KD + R + + K+F+ + +L +P I
Sbjct: 2733 ECLKGPLDLIHLWLHESARVYGDKLIDKKDCDLFQRRMLETAYKYFEGIDSHMLLQQPLI 2792
Query: 2741 FCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILE 2800
+CHFA DP Y+PV D L +L + LD+YNE+NA M+LVLFEDA+ H+CRI+RIL
Sbjct: 2793 YCHFADRGKDPHYMPVKDWEVLKTILTETLDNYNELNAAMHLVLFEDAMQHVCRISRILR 2852
Query: 2801 SPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKN 2860
+P+G ALLVGVGGSGKQSLSRLAAY+ GL+VFQITL +GYGI +L++DLA YI+ KN
Sbjct: 2853 TPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYGIQELRVDLANLYIRTGAKN 2912
Query: 2861 VPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRE 2920
+P+VFL+TD+QV +E FLVLINDLLASGEIP LF +++V+ IIS + +V +LGM D+RE
Sbjct: 2913 MPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDKIISGIHNEVHALGMVDSRE 2972
Query: 2921 TCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSAR 2980
CWKFF+ +VR QLK+ILCFSPVG LRVRARKFPA+VNCTAIDWFH WP++ALVSVS R
Sbjct: 2973 NCWKFFMARVRLQLKIILCFSPVGRTLRVRARKFPAIVNCTAIDWFHAWPQEALVSVSRR 3032
Query: 2981 FLEETEGI-PVIKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLL 3039
F+EET+GI PV K SIS FM++VHTTVNEMS Y ERR+NYTTPK+FLEQI L++NLL
Sbjct: 3033 FIEETKGIEPVHKDSISLFMAHVHTTVNEMSTRYYQNERRHNYTTPKSFLEQISLFKNLL 3092
Query: 3040 AKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEA 3099
KK+ E+ K ERL NG+ KL++TASQV DLKA+LA QEAEL+ +N A+ LI +G++
Sbjct: 3093 KKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQEAELQLRNHDAEALITKIGLQT 3152
Query: 3100 EKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTEL 3159
EKVS+EK IAD EE KV I V +KQ+ CE DL KAEPAL+AA AL+TLN+ NL+EL
Sbjct: 3153 EKVSREKTIADAEERKVTAIQTEVFQKQRECEADLLKAEPALVAATAALNTLNRVNLSEL 3212
Query: 3160 KSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPE 3219
K+F +PP AV NVTAAVM+L AP G++PKD+SWKAAK+ MGKVD FL +L +DKEHIPE
Sbjct: 3213 KAFPNPPIAVTNVTAAVMVLLAPRGRVPKDRSWKAAKVFMGKVDDFLQALINYDKEHIPE 3272
Query: 3220 ACLKAFKP-YQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANA 3278
CLK Y +P F+P IR+KS AAAGLC+W INI++FYEVYCDV PKRQAL +AN
Sbjct: 3273 NCLKVVNEHYLKDPEFNPNLIRTKSFAAAGLCAWVINIIKFYEVYCDVEPKRQALAQANL 3332
Query: 3279 ELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGG 3338
ELA A EKL I+ K+ +L+ NLS LT++FEKATAEK++CQ+E + TN+ I LANRLV
Sbjct: 3333 ELAAATEKLEAIRKKLVDLDRNLSRLTASFEKATAEKVRCQEEVNQTNKTIKLANRLVKE 3392
Query: 3339 LASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLK 3398
L ++ IRW +S+++F +Q TLCGDVLL +AFVSYVG FT++YR EL+ W+P++ K
Sbjct: 3393 LEAKKIRWGQSIKSFEAQEKTLCGDVLLTAAFVSYVGPFTRQYRQELVHCKWVPFLQQ-K 3451
Query: 3399 VPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIK 3458
V IP+T GLD +S+LTDDA +A WNN+GLPSDRMSTENA IL + ERWPL++D Q QGIK
Sbjct: 3452 VSIPLTEGLDLISMLTDDATIAAWNNEGLPSDRMSTENAAILTHCERWPLVIDPQQQGIK 3511
Query: 3459 WIKNKYRSELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGK 3518
WIKNKY +LK LGQK +L+ IE A++ GD +LIEN+ ET+DPVLDPLLGRNTIKKGK
Sbjct: 3512 WIKNKYGMDLKVTHLGQKGFLNAIETALAFGDVILIENLEETIDPVLDPLLGRNTIKKGK 3571
Query: 3519 YIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKE 3578
YI+IGDKE E++ FRLILHTK NPHYKPE+QAQ TL+NF VT DGLE QLLA VV+ E
Sbjct: 3572 YIRIGDKECEFNKNFRLILHTKLANPHYKPELQAQTTLLNFTVTEDGLEAQLLAEVVSIE 3631
Query: 3579 RPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEI 3638
RPDLE+LK LTK QN+FKI LK LED LL RLSAA G+FL DT LVE LE TK T +EI
Sbjct: 3632 RPDLEKLKLVLTKHQNDFKIELKYLEDDLLLRLSAAEGSFLDDTKLVERLEATKTTVAEI 3691
Query: 3639 EEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAI 3698
E KV+EAK E KINEARE YRP A RASLLYF++NDL KINP+YQFSLKAFNV+F +AI
Sbjct: 3692 EHKVIEAKENERKINEARECYRPVAARASLLYFVINDLQKINPLYQFSLKAFNVLFHRAI 3751
Query: 3699 QRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVEL 3758
++ +++ R+ L + IT++V++YT++ LFE+DKL FL+Q+ FQ+L KKE++P+EL
Sbjct: 3752 EQADKVEDMQGRISILMESITHAVFLYTSQALFEKDKLTFLSQMAFQILLRKKEIDPLEL 3811
Query: 3759 DFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPE 3818
DFLLRF + +SPVDFL Q W IKA++ M+EF+ +D D+EGSAK+W+K VESE PE
Sbjct: 3812 DFLLRFTVEHTHLSPVDFLTSQSWSAIKAIAVMEEFRGIDRDVEGSAKQWRKWVESECPE 3871
Query: 3819 KEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESS 3878
KE P+EWK K+ +QKL ++R +RPDRMTYA++NFVEEK+G+K+VE ++ K++EESS
Sbjct: 3872 KEKLPQEWKKKSLIQKLILLRAMRPDRMTYALRNFVEEKLGAKYVERTRLDLVKAFEESS 3931
Query: 3879 PSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGH 3938
P+T IFFILSPGVD LKD+E LGK+LGFTID+GK HNVSLGQGQE VAE AL+ A++ GH
Sbjct: 3932 PATPIFFILSPGVDALKDLEILGKRLGFTIDSGKFHNVSLGQGQETVAEVALEKASKGGH 3991
Query: 3939 WVILQNIHLVARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKI 3998
WVILQN+HLVA+WLGTL+K LER+S GSH DYRVF+SAE AP+P+ HIIPQG+LEN+IKI
Sbjct: 3992 WVILQNVHLVAKWLGTLEKLLERFSQGSHRDYRVFMSAESAPTPDEHIIPQGLLENSIKI 4051
Query: 3999 TNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNR 4058
TNEPPTGM ANLH AL F QDTLE+C+KE EFK +LF+LCYFHA VA R +FG QGW+R
Sbjct: 4052 TNEPPTGMLANLHAALYNFDQDTLEICSKEQEFKSILFSLCYFHACVAGRLRFGPQGWSR 4111
Query: 4059 SYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEY 4118
SYPFN GDLTI +VLYNYLEAN KVPW+DLRYLFGEIMYGGHITDDWDR+LCR YL E+
Sbjct: 4112 SYPFNPGDLTICASVLYNYLEANSKVPWEDLRYLFGEIMYGGHITDDWDRKLCRVYLEEF 4171
Query: 4119 IRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEK 4178
+ + E +++LAPGF PP LDY GYH+YI+E LPPESP LYGLHPNAEI FLTVTS
Sbjct: 4172 MNPSLTEDELMLAPGFAAPPYLDYAGYHQYIEEMLPPESPALYGLHPNAEIEFLTVTSNT 4231
Query: 4179 LFRTVLEMQPKETDSGAGTGVSREEKVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVV 4238
LFRT+LEMQP+ SG G S EEKVK VLDDILEK+PE FNMAEIM K + ++PYV+V
Sbjct: 4232 LFRTLLEMQPRNALSGDELGQSTEEKVKNVLDDILEKLPEEFNMAEIMQKNSNRSPYVLV 4291
Query: 4239 AFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSM 4298
FQECERMNIL E+R SL++L+L LKGEL ++ VE AL YDTVPDTW AYPS
Sbjct: 4292 CFQECERMNILIREIRISLEQLDLSLKGELALSPAVEAQQFALSYDTVPDTWSKLAYPST 4351
Query: 4299 MGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKM 4358
GLA W+ DLLLR REL+ WT D LP VWL+GFFNPQSFLTAIMQ+MARKNEWPLDK
Sbjct: 4352 YGLAQWFNDLLLRCRELDTWTQDLTLPAVVWLSGFFNPQSFLTAIMQTMARKNEWPLDKT 4411
Query: 4359 CLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKA 4418
L+ +VTKK +ED PPREG+Y++GLFMEGARWDTQ G I EARLKEL MPVIF KA
Sbjct: 4412 RLTADVTKKTKEDYGHPPREGAYLHGLFMEGARWDTQAGTIVEARLKELACPMPVIFAKA 4471
Query: 4419 IPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKWILAAVALLLQ 4469
PVDR ETK YECPVY+T++RGP+Y+WTF LK++EK AKW+LA VALLL+
Sbjct: 4472 TPVDRQETKQTYECPVYRTKLRGPSYIWTFRLKSEEKTAKWVLAGVALLLE 4522
>gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]
Length = 4471
Score = 2290 bits (5935), Expect = 0.0
Identities = 1431/4451 (32%), Positives = 2361/4451 (53%), Gaps = 290/4451 (6%)
Query: 132 QVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMERIPSSLDNLLLH 191
Q++ ++ + V + + + +++G+ L +P + S++G + + P ++D L
Sbjct: 194 QLIRDEFLMNVQKFASNIQRTMQQLEGEIKLEMP--IISVEGEVSDLAADPETVDIL--- 248
Query: 192 AIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKCIHEQLNRPKVN 251
E +I+W +QI + AQ P E EFW R L +HEQ P V
Sbjct: 249 --EQCVINWLNQISTAVE---AQLKKTPQGKGPLAEIEFWRERNATLSALHEQTKLPIVR 303
Query: 252 KIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEMEQ-ADFTMLPTF 310
K++++++++ S LQ V+T + + EA+D V +L + + + + F ++
Sbjct: 304 KVLDVIKESDSMLVANLQPVFTELFKFHTEASDNVRFLSTVERYFKNITHGSGFHVVLDT 363
Query: 311 IAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLKGLQGEIEEVL 370
I ++ + +W S +YN R+I +++ +I E ++ + K + +
Sbjct: 364 IPAMMSALRMVWIISRHYNKDERMIPLMERIAWEIAERVCRVVNLRTLFKENRASAQSKT 423
Query: 371 SGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSFFQRIQTIEEL 430
+ + K+ Y +D K+ +E WEF F R + Q + ++
Sbjct: 424 LEARNTLRLWKKAY--FD---TRAKIEASGRED-RWEFDRKRLFERTDYMATICQDLSDV 477
Query: 431 YKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLDPGDSVGPRAG 490
+ EF + EL V G+ + + V LV + +DP
Sbjct: 478 LQILEEFYNIFGPELKAVTGD--PKRIDDVLCRVDGLVTPMENLTFDPF----------- 524
Query: 491 LDELDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSS---AKLLYMCGGLMERP 547
+ S+ Y E KI+ L + IF Q ++ K+ A +Y L R
Sbjct: 525 --SIKSSQFWKYVMDEFKIEVLIDIINKIFVQNLENPPLYKNHPPVAGAIYWERSLFFR- 581
Query: 548 LILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLEL 607
+ R+ + E+ D++ GQ
Sbjct: 582 --IKHTILRFQEVQEILDSD------------------------------RGQ------- 602
Query: 608 QERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFN 667
EV K+L E T ++Y+ ++ Y+QW+ +Q
Sbjct: 603 ----EVKQKYL-----------EVGRTMKEYE----------DRKYEQWMEVTEQVLPAL 637
Query: 668 LGQPLILRDAASN----------LIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFS 717
+ + L+ + + + + +NFS AL ++ E KYL Q +P+ A ++
Sbjct: 638 MKKSLLTKSSIATEEPSTLERGAVFAINFSPALREIINETKYLE-QLGFTVPELARNVAL 696
Query: 718 ENETFRKFVGNLELIVGWYNEV---MKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVF 774
+ + F ++ ++ ++ Y+ + + E +L+K + + S L WN G+
Sbjct: 697 QEDKFLRYTAGIQRMLDHYHMLIGTLNDAESVLLKDHSQELLRVFRSGYKRLNWNSLGIG 756
Query: 775 QYIQEVREILHNLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALL--------- 825
YI ++ + ++ + + +N + IS + A LF+ K E L
Sbjct: 757 DYITGCKQAIGKFESLVHQIHKNADDISSRLTLIEAINLFKYPAAKSEEELPGVKEFFEH 816
Query: 826 ---DLDGRIANLNKRYAAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDE 882
+ + ++ + Y A+ K++ +V + +A L+ Y Y + + +
Sbjct: 817 IERERASDVDHMVRWYLAIGPLLTKVEGLVV-HTNTGKAPKLA----SYYKYWEKKIYEV 871
Query: 883 FDQFIRKSLSFLMDNMVIDESIAPLFEIRMELDEDGLTFNP-TLEVGSDRGFLALIEGLV 941
+ I K+L +++++ PLF L + +P T E+ D+ + V
Sbjct: 872 LTKLILKNLQ-SFNSLILGN--VPLFHTETILTAPEIILHPNTNEI--DKMCFHCVRNCV 926
Query: 942 NDIYNVARLI--------PRLAKDR----MNYKMDLEDNTDLIE----MREEVSSLVINA 985
+ R + P+ ++ +N+ D+ N +IE + + V ++IN
Sbjct: 927 EITKHFVRWMNGSCIECPPQKGEEEEVVIINFYNDISLNPQIIEQAVMIPQNVHRILINL 986
Query: 986 MKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQ 1045
MK Y ++RY LW + M+ F K PP +A +
Sbjct: 987 MK----YLQKWKRYRPLWKLDKAIVMEKF-------------------AAKKPPCVA-YD 1022
Query: 1046 EQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSL 1105
E++ Y K+ EV + K H ++ R + + W + L+ L
Sbjct: 1023 EKLQFYSKIAYEVMRHPLIKDEH-CIRLQLRHLANTVQENAKSWVISLGKLLNESAKEEL 1081
Query: 1106 ADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTY 1165
+L M+ L K + L V+ + +++ + + + +++ + Y
Sbjct: 1082 YNLHEEMEHLAKNLRK--IPNTLEDLKFVLATIAEIRSKSLVMELRYRDVQERYRTMAMY 1139
Query: 1166 GEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRE 1225
P+ + ++ W+N ++ V+ + ++ + R + + ++ EF +
Sbjct: 1140 NLFPPDAEKELVDKIESIWSNLFNDSVNVEHALGDIKRTFTELTRGEIMNYRVQIEEFAK 1199
Query: 1226 RFRREAPFSFSD--PNPYKSLNKQQKSISAMEGIMEALSKSGGLFEVPVPDYKQLKACHR 1283
RF E P S D + L ++ ++ E + L+ + LF++P+ Y +L +
Sbjct: 1200 RFYSEGPGSVGDDLDKGVELLGVYERELARHEKSRQELANAEKLFDLPITMYPELLKVQK 1259
Query: 1284 EVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFV 1343
E+ L+ ++++ + + E+W T W ++NV+ + + F + +R L + ++
Sbjct: 1260 EMSGLRMIYELYEGLKVAKEEWSQTLWINLNVQILQEGIEGFLRALRKLPRPVRGLSVTY 1319
Query: 1344 GLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLADLLQLNLHSYE 1403
L+ +K S+ + +L+N A+R+RHW++LM+ T V F+M+E TL ++ + LH +
Sbjct: 1320 YLEAKMKAFKDSIPLLLDLKNEALRDRHWKELMEKTSVFFEMTETFTLENMFAMELHKHT 1379
Query: 1404 DEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTM----MLKSSEVLVETLE 1459
D + IV A+KE +EK +K + TW M+F + + GT +L S + ++++L+
Sbjct: 1380 DVLNEIVTAAIKEVAIEKAVKEILDTWENMKFTVVKYCK-GTQERGYILGSVDEIIQSLD 1438
Query: 1460 DNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIR 1519
DN LQ++ S+++ FL+ V W++ LS VI IW VQR W +LESIFIG DIR
Sbjct: 1439 DNTFNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFIGG-DIR 1497
Query: 1520 TQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEY 1579
+QLP ++++FD+I++ FK +M + +K P + P + L+ + + L C+K+L +Y
Sbjct: 1498 SQLPEEAKKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSDLQNVSEGLEKCQKSLNDY 1557
Query: 1580 LETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVG 1639
L++KR AFPRF+F+S +LL IL + +DP+ V H+ K++D++ L+F + D K+
Sbjct: 1558 LDSKRNAFPRFFFISDDELLSILGS-SDPLCVQEHMIKMYDNIASLRF--NDGDSGEKLV 1614
Query: 1640 LGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTY-EEKPREQWIL 1698
M S E E M F + G+VE W+ VL+ M T R EA+ Y E++ R W+L
Sbjct: 1615 SAMISAEGEVMEFRKILRAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYCEDRSRVDWML 1674
Query: 1699 DYPAQVALTCTQIWWTTEVGLAFARLEEGYENAIRDYNKKQISQLNVLITLLMGNLNAGD 1758
Y V L +Q+WWT EV F + ++G + A+++Y +K Q++ L+T + L+ D
Sbjct: 1675 LYQGMVVLAASQVWWTWEVEDVFHKAQKGEKQAMKNYGRKMHRQIDELVTRITMPLSKND 1734
Query: 1759 RMKIMTICTIDVHARDVVAKMIVAKVESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQY 1818
R K T+ IDVHARD+V I + ++ F W++QLR WD E C Y
Sbjct: 1735 RKKYNTVLIIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDELNIRQCTGTFGY 1794
Query: 1819 SYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVY 1878
YEY+G RLVITPLTDR Y+TLTQ+L + +GGAPAGPAGTGKTETTKDL +ALG +
Sbjct: 1795 GYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCV 1854
Query: 1879 VFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKA 1938
V NC E MDY++ G I+ GLAQ GAWGCFDEFNRI VLSVI+ Q++ +++A+ +
Sbjct: 1855 VTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTT 1914
Query: 1939 FNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEG 1998
F F G+ I L +GIFITMNPGYAGR ELPE++KALFRP ++VPD + ICEIML +EG
Sbjct: 1915 FQFEGQEISLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEG 1974
Query: 1999 FLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMR 2058
FLEA+ LA+K LY L +E LSKQ HYD+GLRA+KSVLV+AG LKRG ED VLMR
Sbjct: 1975 FLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRGSSDLREDVVLMR 2034
Query: 2059 ALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVL 2118
ALRD N+PK V +D+P+F+GLI DLFP LD PR R +F ++Q + E V
Sbjct: 2035 ALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQVLEENGYAVLPIQVD 2094
Query: 2119 KVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFG 2178
KVVQ+ E + RH+ +VG GKS V+ +L + L L+PKAV+ EL+G
Sbjct: 2095 KVVQMFETMLTRHTTMVVGPTRGGKSVVINTLCQAQTKLGLTTKLYILNPKAVSVIELYG 2154
Query: 2179 IINPVTREWKDGLFSTIMRDLANITHDGP-KWIILDGDIDPMWIESLNTVMDDNKVLTLA 2237
I++P TR+W DG+ S I R++ T K+I+ DGD+D +W+E++N+VMDDN++LTLA
Sbjct: 2155 ILDPTTRDWTDGVLSNIFREINKPTDKKERKYILFDGDVDALWVENMNSVMDDNRLLTLA 2214
Query: 2238 SNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEK 2297
+ ERI L L+FE+ L+ A+PATVSR G++Y++P +L + P W+ + + E+
Sbjct: 2215 NGERIRLQAHCALLFEVGDLQYASPATVSRCGMVYVDPKNLKYRPYWKKWVNQIPNKVEQ 2274
Query: 2298 ANLMILFDKYLPTCLDKLRFG---------FKKITPVPEITVIQTILYLLECLLTEKTVP 2348
NL LF+KY+P +D + G K I P ++ ++ + +L+ LL +
Sbjct: 2275 YNLNSLFEKYVPYLMDVIVEGIVDGRQAEKLKTIVPQTDLNMVTQLAKMLDALLEGEIED 2334
Query: 2349 PDSPRELYELYFVFTCFWAFGGAMFQDQLVDY-----------RVEFSKWWINEFKTIKF 2397
D L E YF+ + + G ++ +D + + V+ W N +
Sbjct: 2335 LD----LLECYFLEALYCSLGASLLEDGRMKFDEYIKRLASLSTVDTEGVWANPG---EL 2387
Query: 2398 PSQ-GTIFDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEK 2456
P Q T++D++ D +++PW+ VP + P+ LVHT +T R + ++ +++
Sbjct: 2388 PGQLPTLYDFHFDNKRNQWVPWSKLVPEYIHAPERKFINILVHTVDTTRTTWILEQMVKI 2447
Query: 2457 SWPVMLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGR 2516
PV+ VG +GT K+ + L++L+ + +V V F+ TTS +Q LE +EK++
Sbjct: 2448 KQPVIFVGESGTSKTATTQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKD 2507
Query: 2517 NYGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHK-LTLKDIHNCQY 2575
YGPP K+L+ F+DDMNMP VD+YGT P L++ ++ + YDR K L K I + +
Sbjct: 2508 TYGPPMGKRLLVFMDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGF 2567
Query: 2576 VACMNPTSGSFT-IDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRIS 2634
+A M G +D R F VF V FP +E+L IY++IL H + + +I +S
Sbjct: 2568 IAAMGKAGGGRNEVDPRFISLFSVFNVPFPSEESLHLIYSSILKGHTS--TFHESIVAVS 2625
Query: 2635 SQLVAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWL 2694
+L LAL++ I PT KFHY+FNLRDLS +F GL+ + E +T +VR+W
Sbjct: 2626 GKLTFCTLALYKNIVQDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWR 2685
Query: 2695 HETERVYGDKMVDEKDQETLHR-VTMASTKKFFDDLGDELLFAKPNIFCHFAQGI--GDP 2751
+E RV+ D+++ E D++ + + + + F DD+ E++ P +F F + G+P
Sbjct: 2686 NECLRVFHDRLISETDKQLVQQHIGSLVVEHFKDDV--EVVMRDPILFGDFQMALHEGEP 2743
Query: 2752 K-YVPVTDMAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVG 2810
+ Y + D L ++L+ YNE N MNLVLF+DA+ H+ R++RI+ RG+ALLVG
Sbjct: 2744 RIYEDIQDYEAAKALFQEILEEYNESNTKMNLVLFDDALEHLTRVHRIIRMDRGHALLVG 2803
Query: 2811 VGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDS 2870
VGGSGKQSLSRLAA+ + +VF+I L +GY + DL + Y+K ++N +FL TD+
Sbjct: 2804 VGGSGKQSLSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDA 2863
Query: 2871 QVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKV 2930
VAEE FL LIN++L SG +P LF E+E E+I+S + + GM +E+ W++F+ K
Sbjct: 2864 HVAEEGFLELINNMLTSGIVPALFSEEEKESILSQIGQEALKQGMGPAKESVWQYFVNKS 2923
Query: 2931 RRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPV 2990
L ++L SPVG LR R FP +VN T IDWF WP AL +V+ FL IP
Sbjct: 2924 ANNLHIVLGMSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNPMIPA 2983
Query: 2991 IK-ASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAK 3049
++ + VH +V+ S+ +L RR NY TPK +L+ I Y LL +K +A+
Sbjct: 2984 ENIENVVKHVVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQ 3043
Query: 3050 IERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIA 3109
+RL+ GL KL+ Q+D+L KLA Q+ L +K+ + + L++ + + ++K +A
Sbjct: 3044 CKRLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLA 3103
Query: 3110 DQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAV 3169
+++ +++E NK + ++ ET LA+ P L AA+ L L+K+++TE++SF PP V
Sbjct: 3104 EEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQV 3163
Query: 3170 VNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQ 3229
V ++I+ K K+ +WK AK +M FL SL + D + I ++ +K K
Sbjct: 3164 QTVCECILIM-----KGYKELNWKTAKGVMSD-PNFLRSLMEIDFDSITQSQVKNIKGLL 3217
Query: 3230 GNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSR 3289
E + + S A G+ + ++ + +V+ ++ PKR+ + + +L R
Sbjct: 3218 KTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELER 3277
Query: 3290 IKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAES 3349
I+N++A + L L + +E A EK K Q+EA+ R ++ A++L+ GL SENIRW
Sbjct: 3278 IQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLND 3337
Query: 3350 VENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDP 3409
++ + V L GD LL +AF+SY G FT ++R+E++ + W I L+ IP++
Sbjct: 3338 LDELMHRRVKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRIWQNDI--LEREIPLSQPFRL 3395
Query: 3410 LSLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNK-YRSEL 3468
SLLTDD +++ W +QGLP D +S +N + R+PL +D Q Q + WIK K ++ L
Sbjct: 3396 ESLLTDDVEISRWGSQGLPPDELSVQNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNL 3455
Query: 3469 KAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRN-TIKKGK-YIKIGDKE 3526
+ +L +E +I G L ++ E +DPV+D +L +N + +G+ +I +GDKE
Sbjct: 3456 RVASFNDPDFLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIKVSQGRQFIILGDKE 3515
Query: 3527 VEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLK 3586
V+Y FRL L+TK NP Y P + + +IN+ VT GLEDQLL+ +VA ER +LE+ +
Sbjct: 3516 VDYDSNFRLYLNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLSVLVAYERRELEEQR 3575
Query: 3587 ANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAK 3646
+L + +E K +LK+LEDSLL L+ ++GN L + LV LE TK A+E+ EK+ A+
Sbjct: 3576 EHLIQETSENKNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETKSKATEVSEKLKLAE 3635
Query: 3647 ITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANE 3706
T + I+ R+ YRPAA R ++L+F+L+++ +N +YQ+SL AF VF +++++ P +
Sbjct: 3636 KTALDIDRLRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLEVFRLSLKKSLPDSI 3695
Query: 3707 VKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPF 3766
+ +R+ N+ D +T+S+Y + GLFER KL+F +T ++ + + ELDF L+
Sbjct: 3696 LMKRLRNIMDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGRVPQEELDFFLKGNI 3755
Query: 3767 ---KAGVVSPVDFLQHQGWGGIKALSEM--DEFKNLDSDIEGSAKRWKKLVESEAPEKEI 3821
K+ P +L QGW I LSEM D F L D+E + W++ + ++ E+
Sbjct: 3756 SLEKSKRKKPCAWLSDQGWEDIILLSEMFSDNFGQLPDDVENNQTVWQEWYDLDSLEQFP 3815
Query: 3822 FPKEWKNK-TALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPS 3880
P + N T QKL ++RC R DR+ A+ ++V MG K+V+ + F +E+S+P
Sbjct: 3816 VPLGYDNNITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPPMISFEAIFEQSTPH 3875
Query: 3881 TSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWV 3940
+ I FILSPG DP D+ L ++ GF +L +++GQGQE VA L+ A +G W+
Sbjct: 3876 SPIVFILSPGSDPATDLMKLAERSGF--GGNRLKFLAMGQGQEKVALQLLETAVARGQWL 3933
Query: 3941 ILQNIHLVARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITN 4000
+LQN HL+ +WL L+K LER T H D+R++++ +P T P GIL+ ++K+
Sbjct: 3934 MLQNCHLLVKWLKDLEKSLERI-TKPHPDFRLWLTTDP-----TKGFPIGILQKSLKVVT 3987
Query: 4001 EPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSY 4060
EPP G+ N+ + + L+ C FK +++ L +FHAVV ERRKFG GWN Y
Sbjct: 3988 EPPNGLKLNMRATYFKISHEMLDQC-PHPAFKPLVYVLAFFHAVVQERRKFGKIGWNVYY 4046
Query: 4061 PFNNGDLTISINVLYNYL-----EANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYL 4115
FN D + + +L YL + +P++PW L+YL GE+MYGG D +DRR+ Y+
Sbjct: 4047 DFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRILTIYM 4106
Query: 4116 AEYIRTEMLEGDVLL------------APGFQIPPNLDYKGYHEYIDENLPPESPYLYGL 4163
EY+ GD + ++IP + + + E I+ +P ++GL
Sbjct: 4107 DEYL------GDFIFDTFQPFHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTPEVFGL 4160
Query: 4164 HPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKVKAVLDDILEKIPETFNMA 4223
HPNAEIG+ T + ++ +LE+QP+ +S +G+SR++ + V +I K+P+ F++
Sbjct: 4161 HPNAEIGYYTQAARDMWAHLLELQPQTGES--SSGISRDDYIGQVAKEIENKMPKVFDLD 4218
Query: 4224 EIMAK-AAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALF 4282
++ + +P VV QE ER N L M +SL EL L GE+ ++ +++D++ +LF
Sbjct: 4219 QVRKRLGTGLSPTSVVLLQELERFNKLVVRMTKSLAELQRALAGEVGMSNELDDVARSLF 4278
Query: 4283 YDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTA 4342
+P+ W A ++ L W L R + W T+ + P+ +WL+G P+S+LTA
Sbjct: 4279 IGHIPNIWRRLAPDTLKSLGNWMVYFLRRFSQYMLWVTE-SEPSVMWLSGLHIPESYLTA 4337
Query: 4343 IMQSMARKNEWPLDKMCLSVEVTK-KNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAE 4401
++Q+ RKN WPLD+ L +VTK ++ +++ +G +V GL++EGA WD + G + +
Sbjct: 4338 LVQATCRKNGWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGLYLEGADWDIEKGCLIK 4397
Query: 4402 ARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIR----GPTYVWTFNLKTKEKAA 4457
++ K L +P++ I I R++ +N + PVY T +R G V+ +L T +
Sbjct: 4398 SKPKVLVVDLPILKIIPIEAHRLKLQNTFRTPVYTTSMRRNAMGVGLVFEADLFTTRHIS 4457
Query: 4458 KWILAAVALLL 4468
W+L V L L
Sbjct: 4458 HWVLQGVCLTL 4468
>gi|75677365 dynein heavy chain domain 3 [Homo sapiens]
Length = 4427
Score = 2194 bits (5686), Expect = 0.0
Identities = 1364/4039 (33%), Positives = 2146/4039 (53%), Gaps = 194/4039 (4%)
Query: 491 LDELDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLIL 550
LD ++ + DY F I+DL+ + F+ + LL L R I
Sbjct: 446 LDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSAFELVRDVPHGVLLLDTFHRLASREAIK 505
Query: 551 AEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQER 610
+ + LF++EL A + P + + +G+ +W L+ R
Sbjct: 506 RTYDKKAVDLYMLFNSEL--------ALVNRERNKKWPDLEPYVAQYSGKARWVHILRRR 557
Query: 611 LEVSMKHLK--HVEHPVMSGAEAKLTYQKYDEMM-ELLRCHREKIYQQWVAGVDQDCHFN 667
++ M L H + +G E+ TYQ+ + + EL+R K +Q+W + +D+DC
Sbjct: 558 IDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVR----KTFQEWTSSLDKDCIRR 613
Query: 668 LGQPLI-LRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFV 726
L PL+ + + ++ VNF K+L+ + E+ Y + E P ++ E R
Sbjct: 614 LDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWE-RLLFETPHYVVNVAERAEDLRILR 672
Query: 727 GNLELIVGWYNEVMKAV---EFLLIKSELEAIDVKLLSAETTLFWNGEGVFQY-IQEVRE 782
NL L+ YN ++ + E L K + +D K+ L W +G + I E R
Sbjct: 673 ENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALKGASAFFITECRI 732
Query: 783 ILHNLQNRMQKAKQNIEGISQAMKDWSANPL-----------FERKDNKKEALLDLDGRI 831
+Q + + K + I ++ S L E +++++E + ++
Sbjct: 733 HASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEEDQREHRAAVQQKL 792
Query: 832 ANLNKRYAAVRDAGVKIQAMVAENAELFRAD--TLSLPWKDYVIYIDDMVLDEFDQFIRK 889
NL++ + ++ + E+F+ D + W Y+I +D M+ D ++
Sbjct: 793 MNLHQ----------DVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNVKW 842
Query: 890 SLSFLMDNMVIDESIAP--LFEIRMELDED------GLTFNPTLEVGSDRGFLALIEGLV 941
SL L + D +P LF++ + L D + F+PTL+ + G+V
Sbjct: 843 SLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQT---------LAGVV 893
Query: 942 NDIYN-----------VARLIPRLAKDRMNYKMDLEDNTDLIEMREEVSSLVINAMKEAE 990
NDI N + ++ + R + +E + D+ +++ ++SS + N +
Sbjct: 894 NDIGNHLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQ 953
Query: 991 EYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDS 1050
Y +++ Y +W N F+ + + P ++ F I
Sbjct: 954 NYLKTWDMYREIWEINKDSFIHRY--------------------QRLNPPVSSFVADIAR 993
Query: 1051 YEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEA 1110
Y ++ V K E T ++ DC K +L+ W F L L +L
Sbjct: 994 YTEVANNVQK-EETVTNIQFVLLDCSHLKFSLVQHCNEWQNKFATLLREMAAGRLLELHT 1052
Query: 1111 FMKVARMGLTKPLKEGDYDG----LVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYG 1166
++K +++P + + G LV+ + H + A + P+ + +L+ Y
Sbjct: 1053 YLKENAEKISRPPQTLEELGVSLQLVDALKHDL------ANVETQIPPIHEQFAILEKYE 1106
Query: 1167 EEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRER 1226
+ + + L L W ++ + K + + + L F+ K H E
Sbjct: 1107 VPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEKFKTGLIHSADDFKKKAHTLLED 1166
Query: 1227 FRREAPFSFSDP--NPYKSLNKQQKSISAMEGIMEALSKSGGLFEVPVPDYKQLKACHRE 1284
F + F+ + + + + + + AM +L + G+F++ P K L+ +E
Sbjct: 1167 FEFKGHFTSNVGYMSALDQITQVRAMLMAMREEENSLRANLGIFKIEQPPSKDLQNLEKE 1226
Query: 1285 VRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMK--TWDAF 1342
+ L+++W++ + +WKT ++ + E M+ + + L KE K W+
Sbjct: 1227 LDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTAHGLFRRLTKLAKEYKDRNWEII 1286
Query: 1343 VGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKM-SEETTLADLLQLNLHS 1401
+ ++ ++ +S+L+NPA+RERHW Q+ Q +F SE TL +++L +
Sbjct: 1287 ETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQREFDQESESFTLEQIVELGMDQ 1346
Query: 1402 YEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEVLVETLEDN 1461
+ +++ I A KE +E L+ + TW + + P+ G L+ +E + + LEDN
Sbjct: 1347 HVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVPYKDKGHHRLRGTEEVFQALEDN 1406
Query: 1462 QVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQ 1521
QV L + S+++ F K+V W++ LS VI + VQR W +LE+IF+G EDIR Q
Sbjct: 1407 QVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILTVQRQWMYLENIFLG-EDIRKQ 1465
Query: 1522 LPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEYLE 1581
LP +S FD +N +KA+M+ K N + +T PGL + L + L +K+L YLE
Sbjct: 1466 LPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDTLIEMNTILEDIQKSLDMYLE 1525
Query: 1582 TKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLG 1641
TKR FPRFYF+S+ DLL+IL +P V HL K FD++ L+ + +G
Sbjct: 1526 TKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKLLRIQKVGGPSSKWEAVG 1585
Query: 1642 MYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEE--KPREQWILD 1699
M+S + EY+ F L G VE WL V M TLR + + + R++W+ +
Sbjct: 1586 MFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLLRNCHLALRKFLNKRDKWVKE 1645
Query: 1700 YPAQVALTCTQIWWTTEVGLAFARLEEGYENAIRDYNKK-QISQLNVLITLLMGNLNAGD 1758
+ QV +T +QI WT +V +E + I KK Q+S LN + GNL
Sbjct: 1646 WAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKYSEAIRGNLTKIM 1705
Query: 1759 RMKIMTICTIDVHARDVVAKMIVAKVESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQY 1818
R+KI+ + TI++HARDV+ K+ + + +F W +QLR W+++ C + Q QY
Sbjct: 1706 RLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQY 1765
Query: 1819 SYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVY 1878
+YEYLGN+ RLVITPLTDRCY+TLT +LHL GG+P GPAGTGKTET KDLG+ALG V
Sbjct: 1766 NYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVI 1825
Query: 1879 VFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKA 1938
V NCSE +DYKS G +Y GLAQTGAWGCFDEFNRI++EVLSV+A Q+ C+ A+ A
Sbjct: 1826 VVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILCILSALAAGLTH 1885
Query: 1939 FNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEG 1998
F+F G I L+ + GIFITMNPGYAGR ELPENLK++FRP AMVVPD LI EI+L EG
Sbjct: 1886 FHFDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGEG 1945
Query: 1999 FLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMR 2058
F ++LA+K TLY+L + LS+QDHYD+GLRA+ S+L AG +R P +++VL+
Sbjct: 1946 FGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRRLQPDLTDEEVLLL 2005
Query: 2059 ALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVL 2118
++RD NI K+ + D P+F ++ DLFP +++P + ++Q I ++ LQ+ +
Sbjct: 2006 SMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLRETVEQEIRDMGLQSTPFTLT 2065
Query: 2119 KVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRK-------PVAVDLDPKAV 2171
KV QL E RHS IVG GSGK+ + L + +L R L+PKA+
Sbjct: 2066 KVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLCRAGDPNFNIVREFPLNPKAL 2125
Query: 2172 TCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDN 2231
+ EL+G + T EW DG+ S++MR KWI+ DG +D +WIE++N+VMDDN
Sbjct: 2126 SLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWILFDGPVDTLWIENMNSVMDDN 2185
Query: 2232 KVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERR 2291
KVLTL + ERI + + L+FE+ L A+PATVSR G++Y + ADLGW P V SW+E+R
Sbjct: 2186 KVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGMVYTDYADLGWKPYVQSWLEKR 2245
Query: 2292 KVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEKTVPPDS 2351
++E L +F+K + L + K++ P+PE + I ++ L L T + +
Sbjct: 2246 P-KAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGITSLCKLYSALATPENGVNPA 2304
Query: 2352 PRELY----ELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYY 2407
E Y E+ FVF+ W+ ++ D+ R++ ++ E + FP++ T+++Y+
Sbjct: 2305 DGENYVTMVEMTFVFSMIWSVCASV--DEEGRKRIDS---YLREIEG-SFPNKDTVYEYF 2358
Query: 2408 IDPDTKKFLPWTDKVP-SFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNA 2466
+DP + + + DK+P S+ P+ P +V T +T+R Y + L+ P++LVG
Sbjct: 2359 VDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSLVANQNPILLVGPV 2418
Query: 2467 GTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKL 2526
GTGK+ + L+SL + + V V + TTS +Q ++E +EK++ Y P G K +
Sbjct: 2419 GTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKRTKGVYVPFGGKSM 2478
Query: 2527 VYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGSF 2586
+ F+DD+NMP D +G+ P LIR +D+ WYDR K T+K I +A M P G
Sbjct: 2479 ITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYIREMFLMAAMGPPGGGR 2538
Query: 2587 TIDS-RLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALH 2645
T+ S RL+ F + ++FP + + I+ T++ Q L + ++ I + + A L ++
Sbjct: 2539 TVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKL--QDFEEEVKPIGNVVTEATLDMY 2596
Query: 2646 QKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKM 2705
+ FLPT K HY+FNLRD+S +FQG+L + + T + RLW+HE RV+ D++
Sbjct: 2597 NTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWIHECFRVFSDRL 2656
Query: 2706 VDEKDQETLHRVTMASTKKFFDDLGDELLFAK-PNIFCHFAQGIGDPK-YVPVTDMAPLN 2763
VD D E + FFD L +K P IF F + +PK Y +TD+ L
Sbjct: 2657 VDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDF---LKEPKVYEDLTDLTVLK 2713
Query: 2764 KLLVDVLDSYNEVNAV--MNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSR 2821
++ L+ YN +V M LVLF +A+ HI RI R++ PRGN LLVG+GGSG+QSL+R
Sbjct: 2714 TVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLAR 2773
Query: 2822 LAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLI 2881
LA+ I FQI + K Y + + D+ Y +A V+ + F+ D+Q+A+E FL I
Sbjct: 2774 LASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIADESFLEDI 2833
Query: 2882 NDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFS 2941
N++L+SGE+P L+ DE E I S + Q + + ++ ++ + + IE+V+ L ++LC S
Sbjct: 2834 NNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQNNLHIVLCLS 2893
Query: 2942 PVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPV-----IKASIS 2996
P+G R R++PA+VNCT I+WF EWP++AL+ V+ + L G+ + I ++
Sbjct: 2894 PMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCL---IGVDLGTQENIHRKVA 2950
Query: 2997 FFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENG 3056
+H +V + S+ L RR+NY TP +LE + Y+ LL +KR EL+A+ +L G
Sbjct: 2951 QIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTG 3010
Query: 3057 LMKLQSTASQVDDLKAKLAIQEAELKQ-KNESADQLIQVVGIEAEKVSKEKAI-ADQEEV 3114
L K+ T +V + +L + ++ + + + + L+ +V + E ++KA+ A+ E++
Sbjct: 3011 LFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKI 3070
Query: 3115 KVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTA 3174
VE I + DL +A PAL A AL++LNK ++ E+KS+G PP V V
Sbjct: 3071 AVEEIKCQALADN--AQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQ 3128
Query: 3175 AVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTF 3234
AVMIL + +W AK +G+ F+ SL FDK++I + LK Y P F
Sbjct: 3129 AVMILRG------NEPTWAEAKRQLGE-QNFIKSLINFDKDNISDKVLKKIGAYCAQPDF 3181
Query: 3235 DPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKI 3294
P+ I S AA LC W + + +Y V PKR + A A+L E Q L+ + K+
Sbjct: 3182 QPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKL 3241
Query: 3295 AELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFR 3354
E+ L L +++ A+K + +++++ + A LV GLA E RW E+V+
Sbjct: 3242 REVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLE 3301
Query: 3355 SQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLT 3414
L GD LL +AF+SY+G F YR+E++ + WI I L+VP + +D + L
Sbjct: 3302 EDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAID--NFLC 3359
Query: 3415 DDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSE-LKAIRL 3473
+ V WN QGLPSD STEN I+ RW L++D Q Q +KWIKN + LK I L
Sbjct: 3360 NPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDL 3419
Query: 3474 GQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKG--KYIKIGDKEVEYHP 3531
YL ++E AI G +L++N+ E +DP L+P+L ++ + G ++IGDKEVEY+
Sbjct: 3420 QMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNT 3479
Query: 3532 KFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTK 3591
FR + TK NPHY PE A+ T++NF V GLE QLL VV KERP+LE+ K +L
Sbjct: 3480 NFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVI 3539
Query: 3592 SQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVK 3651
+ K LKELED +L L+ A+G+ L D LV L T+K TA+E+ E++ ++ TE+
Sbjct: 3540 NIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEIN 3599
Query: 3652 INEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRV 3711
+ ARE YRP A+RAS+L+F+LND+ I+P+YQFSL A+ +F +I ++ +N+++ R+
Sbjct: 3600 TDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRI 3659
Query: 3712 INLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVV 3771
L D TY+VY YT R LFER KL+F + ++L +LN E +F LR GVV
Sbjct: 3660 DYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLR----GGVV 3715
Query: 3772 --------SPV-DFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIF 3822
+P +L W I L ++ F L + E + W + APEK +
Sbjct: 3716 LDREGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAML 3775
Query: 3823 PKEWKNK-TALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPST 3881
P EW+N +Q++ +VR LR DR+ + + +F+ +GS+F+E + E+S+P +
Sbjct: 3776 PGEWENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRS 3835
Query: 3882 SIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVI 3941
+ FILSPGVDP + L + +G + H +SLGQGQ +A L +GHWV
Sbjct: 3836 PLVFILSPGVDPTSALLQLAEHMGMA---QRFHALSLGQGQAPIAARLLREGVTQGHWVF 3892
Query: 3942 LQNIHLVARWLGTLDKKLERYST-GSHEDYRVFISAEPAPSPETHIIPQGILENAIKITN 4000
L N HL W+ LDK +E+ H +R+++S+ P P P IL+ +IK+T
Sbjct: 3893 LANCHLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPD-----FPISILQVSIKMTT 3947
Query: 4001 EPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSY 4060
EPP G+ AN+ + L ++ C+K ++K +LF+LC+FH+V+ ER+KF GWN Y
Sbjct: 3948 EPPKGLKANMTRLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIY 4007
Query: 4061 PFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIR 4120
FN+ D +S N+L YL+ + PWD L+YL I YGGH+TDDWDRRL TY+ +Y
Sbjct: 4008 GFNDSDFEVSENLLSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFC 4067
Query: 4121 TEMLEGD---VLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSE 4177
+ L + + IP + Y EYI + P +G HPNA++ ++
Sbjct: 4068 DQSLSTPFHRLSALETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQ 4127
Query: 4178 KLFRTVLEMQPKETDSGAGTGVSREEKVKAVLDDILEKIPETFNMAEIM-AKAAEKTPYV 4236
LF T+L +QP+ T + AG G +REEKV + D+ +KIPE + A + +P
Sbjct: 4128 TLFDTLLSLQPQITPTRAG-GQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLN 4186
Query: 4237 VVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYP 4296
VV QE +R N L + SL +L G++G + ++T +E++ +F VP W +AYP
Sbjct: 4187 VVLLQEIQRYNTLMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLW-GKAYP 4245
Query: 4297 SMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLD 4356
S LAAW DL +R+ + E W + P WL+GF P FLTA++QS AR+N +D
Sbjct: 4246 SQKPLAAWTRDLAMRVEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVD 4305
Query: 4357 KMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFI 4416
+ V+ + ++ PP++G +V GL++EGA WD + + EA +L MP I
Sbjct: 4306 SLSWEFIVSTVDDSNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHF 4365
Query: 4417 KAIPVDRMETKNIYECPVY 4435
+ + K +Y CP Y
Sbjct: 4366 RPAESRKKSAKGMYSCPCY 4384
Score = 107 bits (268), Expect = 2e-22
Identities = 74/315 (23%), Positives = 147/315 (46%), Gaps = 16/315 (5%)
Query: 31 IGAEENVALFTEFFEKPDVQVLVLTLNAAGMIIPCLGFPQSLKSKGVYFIKTKSENINKD 90
+ +E+ A+ F + P +L + ++ + LG P +++ VYFI+ I +
Sbjct: 93 VWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVYFIRQAPVPITWE 152
Query: 91 NYRARLLYGDISPTPVDQLIAVVEEVLSSLLNQSENMAGWPQVVSEDIVKQVHRLKNEMF 150
N+ A + +G + + L+ ++ V + + + GWP+ + +H+ +
Sbjct: 153 NFEATVQFGTVRGPYIPALLRLLGGVFAPQIFAN---TGWPESIRNHFASHLHKFLACLT 209
Query: 151 VMSGKIKGKTLLPIPEHLGSLDGTLESMERIPSSL--DNLLLHAIETTIIDWSHQIRDVL 208
K++G T+L IP E+M P + D L+ +ET++I W+ QI+++L
Sbjct: 210 DTRYKLEGHTVLYIPA---------EAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEML 260
Query: 209 SKDSAQALLDGLHPLPQVEFEFWDARLLNLKCIHEQLNRPKVNKIVEILEKAKSCYWPAL 268
S + L PL ++EF W R ++L I +QL + V + IL AKS Y
Sbjct: 261 SAQETVETGENLGPLEEIEF--WRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPF 318
Query: 269 QNVYTNVTEGLKEANDIVLYLKPLRILLEEMEQADFTMLPTFIAKVLDTICFIWATSEYY 328
+ + +G ++A + +L L+ +E+ + + + K++ I IW S +Y
Sbjct: 319 MKLAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHY 378
Query: 329 NTPARIIVILQEFCN 343
NT R+ + ++ C+
Sbjct: 379 NTRERLTSLFRKVCD 393
>gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens]
Length = 4158
Score = 2027 bits (5252), Expect = 0.0
Identities = 1240/3746 (33%), Positives = 1979/3746 (52%), Gaps = 219/3746 (5%)
Query: 875 IDDMVLDEFDQFIRKSLSFLMDNMVIDESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFL 934
I + +E + K + +++ DES+ P+F + L L F P+LE FL
Sbjct: 480 IQKWITEEKPEVPDKKGTLMVEKQEEDESLIPMFLTELMLTVQSLLFEPSLE-----DFL 534
Query: 935 ALIEGLVNDIYNVARLIPRLAKDR---------MNYKMD-------------LEDNTDLI 972
I G VN N +P L D +N K++ ED+ +
Sbjct: 535 DGILGAVNHCQNTVLSVPNLVPDSYFDAFTSPYINNKLEGKTCGTGPSLAAVFEDDKNFH 594
Query: 973 EMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDD 1032
+ ++ + A + A Y +FE++ + +N E LD
Sbjct: 595 TIISQIKETIQAAFESARIYAATFEKFQIFFKEN-----------------ESLDL---Q 634
Query: 1033 TIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRW--- 1089
+ P + F EQ++ Y K +++ T+ G L D R ++ L+ + R
Sbjct: 635 ALKLQEPDINFFSEQLEKYHKQHKDAVALRPTRNV-GLLLIDTRLLREKLIPSPLRCLEV 693
Query: 1090 -GFMFKRHLSNHVTNSLADLE-AFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAA 1147
FM R V + + + A K+ + P +Y V + L +++ER +
Sbjct: 694 LNFMLPRQSKKKVDAIIFEAQDAEYKLEFV----PTTTTEY---VHSLLFLDEIQERIES 746
Query: 1148 TDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVS 1207
++ + Q +L++ Y P E +A K + V+ + + S
Sbjct: 747 LEDEGNIVTQMYKLMEQYQVPTPPEDFAV-------FATMKPSIVAVRNAIDKSVGDRES 799
Query: 1208 ILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKQQKS---ISAMEGIMEALSKS 1264
+++ C E E DP Q K ++ ++ ++ L K
Sbjct: 800 SIKQFCVHLGSDLEELNNEVN-EVKLQAQDPQILDISADQDKIRLILNNLQSVLADLQKR 858
Query: 1265 GGL-------FEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQ 1317
F+V V ++ L+ E++L + LWD + ++W +K+ ++ E
Sbjct: 859 AFQYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDSFSEWDKLQQEWLKSKFDCLDPEV 918
Query: 1318 MDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQ 1377
++ K+AK + L+K + L V+ + L + +L+NP ++ RHW + Q
Sbjct: 919 LNGQVSKYAKFVTQLEKGLPPNSVVPQLKYKVEKMKEKLPVIIDLRNPTLKARHWAAIEQ 978
Query: 1378 ATQVKFKMSE-ETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQ 1436
+E TL L QL++ + E+++I +A E+ +E +LK ++ +W EF
Sbjct: 979 TVDATLVDAEIPLTLERLSQLHVFDFGQEIQDISGQASGEAALEAILKKVEDSWKTTEFV 1038
Query: 1437 HEPHPRT-GTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVI 1495
PH + +L ++ + L+D+ + + L S+YL V WQ++L+ + +
Sbjct: 1039 ILPHRDSKDVFILGGTDDIQVLLDDSTINVATLASSRYLGPLKTRVDEWQKQLALFNQTL 1098
Query: 1496 SIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSK 1555
W QR W +LESIF + DI+ QLP +++ F +++ +K +M + PN + A ++
Sbjct: 1099 EEWLTCQRNWLYLESIF-NAPDIQRQLPAEAKMFLQVDKSWKEIMRKVNRLPNALRAATQ 1157
Query: 1556 PGLYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHL 1615
PGL + L +K L YLE+KR+ FPRFYF+S+ +LL+IL+ +P V HL
Sbjct: 1158 PGLLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDELLEILAQTRNPQAVQPHL 1217
Query: 1616 SKLFDSLCKLKFRL---------DASDKPLKVG----LGMYSKEDEYMVFDQECDLSGQV 1662
K FDS+ KL+F L +P KV L M S E E + + G V
Sbjct: 1218 RKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTNDILAMLSPEGERVSLGKGLKARGNV 1277
Query: 1663 EVWLNRVLDRMCSTLRHEIPEAVVTYEEKPREQWIL-DYPAQVALTCTQIWWTTEVGLAF 1721
E WL +V + M ++LR A+ Y+ K R W++ +P+QV LT +QI W ++
Sbjct: 1278 EEWLGKVEEAMFTSLRRLCKAAIADYQGKLRTDWVVAGHPSQVILTVSQIMWCRDLTECL 1337
Query: 1722 ARLEEGYENAIRDYNKKQISQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIV 1781
+ A++++ K +LN L ++ G+L R + + TIDVHARD+V +++
Sbjct: 1338 ETEHSNHIQALKNFEKVNFERLNALAAIVQGSLPKLHRNILTALITIDVHARDIVTELVQ 1397
Query: 1782 AKVESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYIT 1841
+KVE+ ++F WQ QLR+ WD + +C A + +Q Y YEYLG PRLVITPLTDRCY+
Sbjct: 1398 SKVETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGYEYLGACPRLVITPLTDRCYLC 1457
Query: 1842 LTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQT 1901
L +L L +GGAPAGPAGTGKTETTKDL +AL VFNCS+ +DYK G + GLAQ+
Sbjct: 1458 LMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMMGRFFSGLAQS 1517
Query: 1902 GAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPG 1961
GAW CFDEFNRI +EVLSVIA Q+ +++A AK F F G I L+ T FITMNPG
Sbjct: 1518 GAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMFEGREIKLVMTCAAFITMNPG 1577
Query: 1962 YAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLS 2021
YAGR ELP+NLKALFRP AM+VP++ LI E++L +EGF +++LARK +Y LC E LS
Sbjct: 1578 YAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESSKILARKMTQMYKLCSEQLS 1637
Query: 2022 KQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIG 2081
+QDHYD+G+RA+KSVLV+AGSLKR +P ED VL+RAL+D N+PK +TDD +F G+I
Sbjct: 1638 QQDHYDFGMRAVKSVLVMAGSLKRENPDLNEDVVLIRALQDSNLPKFLTDDALLFSGIIS 1697
Query: 2082 DLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGS 2141
DLFP + +P + I + LQ E V KV+Q E + VRH V +VG G
Sbjct: 1698 DLFPGVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRKVIQFYETMLVRHGVMLVGPTGG 1757
Query: 2142 GKSQVLKSLNKTYQNLKRKPV---------AVDLDPKAVTCDELFGIINPVTREWKDGLF 2192
GK+ V + L +T NL++ + L+PK++T EL+G +N +T EWKDGL
Sbjct: 1758 GKTTVYRILAETLGNLQKLGIENSFYQAVKTYVLNPKSITMGELYGEVNNLTLEWKDGLM 1817
Query: 2193 STIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVF 2252
+ +R N T + KWII DG +D +WIE++NTV+DDNK+L LA++ERI L + ++F
Sbjct: 1818 ALSVRAAVNDTSEDHKWIISDGPVDALWIENMNTVLDDNKMLCLANSERIKLTPQIHMLF 1877
Query: 2253 EISHLRTATPATVSRAGILYINPADLGWNPVVSSW---IERRKVQSEKANLMILFDKYLP 2309
E+ LR A+PATVSR G+++++P +L W P V +W I ++ + + ++ LF +Y+
Sbjct: 1878 EVQDLRVASPATVSRCGMVFVDPEELKWMPYVKTWMKGISKKLTEETQEYILNLFQRYVD 1937
Query: 2310 TCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEK-----TVPPDSPRELYELYFVFTC 2364
L + + P +I+ + T+ LLE L+ K + + FVF
Sbjct: 1938 EGLHFINKKCSQAIPQVDISKVTTLCCLLESLILGKDGVNLAMEQTKLNTILCQTFVFCY 1997
Query: 2365 FWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKKFLPWTDKVPS 2424
W+ GG + ++ + F + ++ + P+ G ++ ++D DTK+ PW +P+
Sbjct: 1998 LWSLGGNLTENYYDSFDT-FIRTQFDDNPDARLPNSGDLWSIHMDFDTKRLDPWERIIPT 2056
Query: 2425 FELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESL-NT 2483
F+ + DVP LV TT+T+R Y M+ L+ V+ G G GKSV+ L + +
Sbjct: 2057 FKYNRDVPFFEMLVPTTDTVRYGYLMEKLLAVKHSVLFTGITGVGKSVIAKGLLNKIQES 2116
Query: 2484 DNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGT 2543
Y+ + F+ T+SA Q ++E LE+K G PG K++V F+DD+NMP +D+YG+
Sbjct: 2117 AGYVPVYLNFSAQTSSARTQEIIESKLERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGS 2176
Query: 2544 VAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYV-ACMNPTSGSFTIDSRLQRHFCVFAVS 2602
P L+RQ+ D +YDR+KL K+I + + AC P G + R RHF + +
Sbjct: 2177 QPPIELLRQYQDFGGFYDRNKLFWKEIQDVTIISACAPPGGGRNPVTPRFIRHFSMLCLP 2236
Query: 2603 FPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYV 2662
P + +L I+ IL L+ A+++ +S +V A++ ++ K++ LPT K HYV
Sbjct: 2237 MPSEHSLKQIFQAILNGFLS--DFPPAVKQTASSIVEASVEIYNKMSVDLLPTPAKSHYV 2294
Query: 2663 FNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMAST 2722
FNLRDLS QG+L ++ + + RL+ HE +RV+ D++++ +D+ H +
Sbjct: 2295 FNLRDLSKCVQGILQCDPGTIREEIQIFRLFCHECQRVFHDRLINNEDKHYFHVILTEMA 2354
Query: 2723 KKFFDDLGD-ELLFAKPNI---FCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNEVN- 2777
K F D E KP I F F D Y + D+ +L D LD YN N
Sbjct: 2355 NKHFGIAIDLEYFLNKPIIFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDYNLTNP 2414
Query: 2778 AVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLK 2837
+ LV F+DA+ H+ RI R++ RGNALLVGVGG+GKQSL+RLAA+I G QI L
Sbjct: 2415 KEVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELS 2474
Query: 2838 KGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMED 2897
+GY DL Y A V++ VFL TD+Q+ E+FL IN++L SGE+P LF +D
Sbjct: 2475 RGYNYDSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKD 2534
Query: 2898 EVENIISSMRPQVKSLGMND-TRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPA 2956
E+E ++++ RP+ K +G+++ R+ +++FI KVR++L ++LC SPVG R R R FP+
Sbjct: 2535 ELEQVLAATRPRAKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSPVGEAFRSRCRMFPS 2594
Query: 2957 VVNCTAIDWFHEWPEDALVSVSARFLEETE-GIPVIKASISFFMSYVHTTVNEMSRVYLA 3015
+VNC IDWF +WP +AL+SVS F + + G +K + VH +V+ M+ Y
Sbjct: 2595 LVNCCTIDWFVQWPREALLSVSKTFFSQVDAGNEELKEKLPLMCVNVHLSVSSMAERYYN 2654
Query: 3016 TERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLA 3075
RR YTTP ++LE I LY ++L++KR ++++ +R++NGL KL T VD +K L+
Sbjct: 2655 ELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLS 2714
Query: 3076 IQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLA 3135
E L K+E + L++ + ++ E + + ++E +V + + DL
Sbjct: 2715 ALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQRDLD 2774
Query: 3136 KAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAA 3195
+A PAL AA +ALD+L+K +++E++ F PPD V+ V A+ IL + W +A
Sbjct: 2775 EALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISIL------LNAKPDWPSA 2828
Query: 3196 KIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCIN 3255
K ++G FL L ++DKE+I L + Y NP F PE + S A +C W
Sbjct: 2829 KQLLGD-SNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCMWVRA 2887
Query: 3256 IVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEK 3315
+ + V V PKRQ L A AEL L + + ++ + L ++K EK
Sbjct: 2888 MDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKGVNEK 2947
Query: 3316 IKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVG 3375
+ T ++ A +L L E +RW ES++ F + + G+V + +A V+Y G
Sbjct: 2948 ESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAACVAYYG 3007
Query: 3376 YFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTE 3435
FT +YR L+E WI +L++PI + L +++L D ++ WN GLP D +STE
Sbjct: 3008 AFTAQYRQSLIE-CWIQDCQSLEIPIDPSFSL--INILGDPYEIRQWNTDGLPRDLISTE 3064
Query: 3436 NATILGNTERWPLIVDAQLQGIKWIKNK-YRSELKAIRLGQKSYLDVIEQAISEGDTLLI 3494
N ++ RWPL++D Q Q +WI+NK +S LK I+L ++L ++E +I G +L+
Sbjct: 3065 NGILVTQGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGLPVLL 3124
Query: 3495 ENIGETVDPVLDPLLGRNTIKKG--KYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQA 3552
E + ET+DP L+P+L + G I++GD +++Y FR + TK NPHY PE+
Sbjct: 3125 EELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLPEVCI 3184
Query: 3553 QCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLS 3612
+ T+INF VT+ GLEDQLL+ VV E+P LE+ + L N K LK +E+ +L L
Sbjct: 3185 KVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKILRMLF 3244
Query: 3613 AASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFI 3672
+ GN L + L++ L+ +K T+ I+ ++ EA+ TE IN ARE YRP A + S++YF+
Sbjct: 3245 TSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSVMYFV 3304
Query: 3673 LNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFE 3732
+ L++I+P+YQ+SLK F +F I+ + ++QR+ L ++ + Y+ +RGLFE
Sbjct: 3305 IASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSRGLFE 3364
Query: 3733 RDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSP----VDFLQHQGWGGIKAL 3788
+ KLI+ + +++ + L+ E +F LR P +L W L
Sbjct: 3365 QHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAPWLPTATWFACCDL 3424
Query: 3789 SE-MDEFKNLDSDIEG--------------SAKRWKKLVESEAPEKEIFPKE-------W 3826
E F L +I + ++W+ + + +K + ++ W
Sbjct: 3425 EESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAHQDPW 3484
Query: 3827 K-NKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFF 3885
++ KL +++C + +++ +A+ +FV E +G +F+E V+ Y++ S +T + F
Sbjct: 3485 SAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNTPLVF 3544
Query: 3886 ILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQNI 3945
ILS G DP+ + ++ G+ + ++ ++SLGQGQ +AE + A + G+WV LQN
Sbjct: 3545 ILSTGSDPMGAFQRFARESGY---SERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQNC 3601
Query: 3946 HLVARWLGTLDKKLERYS---TGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEP 4002
HL W+ +++ ++ ++ + + +R+F+S+ P ++ P +L+N++K+TNEP
Sbjct: 3602 HLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMP-----SNTFPVTVLQNSVKVTNEP 3656
Query: 4003 PTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPF 4062
P G+ AN+ +A T E +++ ++F +C+FHA++ ER+KFG GWN Y F
Sbjct: 3657 PKGLRANIRRAFTEMTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEF 3716
Query: 4063 NNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTE 4122
N+ D ++ L Y + K+PWD L Y+ GEI YGG +TD WD+R RT L + E
Sbjct: 3717 NDSDRECALLNLKLYCKEG-KIPWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPE 3775
Query: 4123 MLEGDVLLA-PGFQIPPNLD-YKGYHEYIDENLP-PESPYLYGLHPNAEIGFLTVTSEKL 4179
LE D + G P D + + +YI ENLP + P ++G+H NA + F + L
Sbjct: 3776 TLEEDYKYSESGIYFAPMADSLQEFKDYI-ENLPLIDDPEIFGMHENANLVFQYKETSTL 3834
Query: 4180 FRTVLEMQPKETDSGAGTGVSREEKVKAVLDDILEKIPETFNMAEIMAKAAEK------T 4233
T+LE+QP+ S G G S +E V+ ++ + ++PE M K
Sbjct: 3835 INTILEVQPR--SSTGGEGKSNDEIVQELVASVQTRVPEKLEMEGASESLFVKDLQGRLN 3892
Query: 4234 PYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVAR 4293
V QE +R N L + SL+ LN + G + ++ ++E + + + VP W
Sbjct: 3893 SLTTVLGQEVDRFNNLLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNT 3952
Query: 4294 AYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEW 4353
AYPS+ L +W DL+LR ++ W P + W++GFF PQ FLT +Q+ ARK
Sbjct: 3953 AYPSLKPLGSWVKDLILRTSFVDLWLKR-GQPKSYWISGFFFPQGFLTGTLQNHARKYNL 4011
Query: 4354 PLDKMCLSVEVTKKNRE-------------------DMTAP-PREGSYVYGLFMEGARWD 4393
P+D++ V R+ DM P P +G V+G+FM+ +RWD
Sbjct: 4012 PIDELSFKYSVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPEDGVLVHGMFMDASRWD 4071
Query: 4394 TQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPT---------Y 4444
+ VI +A ++ P +PV+ + + + +Y CP+YKT R T +
Sbjct: 4072 DKEMVIEDALPGQMNPVLPVVHFEP-QQNYKPSPTLYHCPLYKTGARAGTLSTTGHSTNF 4130
Query: 4445 VWTFNLKTKEKAAKWILAAVALLLQV 4470
V T L +K WI ALL Q+
Sbjct: 4131 VVTVLLPSKRSKDYWIAKGSALLCQL 4156
>gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]
Length = 4265
Score = 2019 bits (5231), Expect = 0.0
Identities = 1250/3734 (33%), Positives = 1994/3734 (53%), Gaps = 238/3734 (6%)
Query: 880 LDEFDQFIRKSLSFLM---DNMVIDESIA---------PLFEIRMELDEDGLTFNPTLEV 927
L F QFI + ++ D+MV + + PLF + + LD G+ ++ LE
Sbjct: 619 LASFSQFISDTCCSVLNCTDDMVWGDDLINSPYRPRKNPLFIMDLVLDSSGVHYSTPLEQ 678
Query: 928 GS-------DRGFLAL-----IEGLV-NDIYNVARLIPRLAKDRMNYKMDLEDNTDLIEM 974
D+G LA +E LV DI+ ++ D + + L + + E+
Sbjct: 679 FEASLLNLFDKGILATHAVPQLEKLVMEDIF--------ISGDPLLESVGLHEPL-VEEL 729
Query: 975 REEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDDTI 1034
R ++S V AM + Y + +Y L +++ F+K +
Sbjct: 730 RATIASAVSKAMIPLQAYAKEYRKYLELNNNDIASFLKTY-------------------- 769
Query: 1035 PKTPPTLAQ-FQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRWGFMF 1093
+T LAQ +E + ++ + E + + + G + KQ+L +
Sbjct: 770 -QTQGLLAQEVREVVLTHLREKEILDSSLPSSIIIGPFYINTDNVKQSLSKKRKALATSV 828
Query: 1094 KRHLSNHVTNSLADL-EAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAATDNMF 1152
L+ ++ + + E F ++R KP + L E+ + + ER +
Sbjct: 829 LDILAKNLHKEVDSICEEFRSISRKIYEKP---NSIEELAELREWMKGIPERLVGLE--- 882
Query: 1153 EPLKQTIELLKTYGEEMPEEIH-LKLQELPEHWANTK---KLAIQVKLTVAPLQANEVSI 1208
++ ++++ Y + M E ++ L + + W + K+ Q++L +E
Sbjct: 883 ---ERIVKVMDDY-QVMDEFLYNLSSDDFNDKWIASNWPSKILGQIELVQQQHVEDEEKF 938
Query: 1209 LRRKCQQFELKQHEFRERFRR------------EAPFSFSDPNPYKSLNKQQKSISAMEG 1256
RK Q + Q+ F+E+ E + N + + KQ K +
Sbjct: 939 --RKIQIMD--QNNFQEKLEGLQLVVAGFSIHVEISRAHEIANEVRRVKKQLKDCQQLAM 994
Query: 1257 IMEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVE 1316
+ + +F +P+ +Y +L +E + +LW E W I+ E
Sbjct: 995 LYNNRER---IFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAE 1051
Query: 1317 QMDIDCKKFAKDMRSLDKEMKTWDAF--VGLD--NTVKNVITSLRAVSELQNPAIRERHW 1372
Q++ + + K M K+ K A V LD ++ + + L+NP +R RHW
Sbjct: 1052 QLEKNVVEAFKTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHW 1111
Query: 1373 QQLMQATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSM 1432
+ L + + T A L++NL + + + + + A KE +E+ L ++ WS
Sbjct: 1112 ETLSNQININVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWST 1171
Query: 1433 MEFQHEPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTAD 1492
+ F P+ T T +LKS + + L+D+ V QN+ S Y F + + SW+ KL
Sbjct: 1172 ILFNVLPYKATDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQ 1231
Query: 1493 SVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEA 1552
V+ W QR+W +LE IF SEDI QLP +S+R+ + + +K +M++A + V+
Sbjct: 1232 EVLEEWLNCQRSWLYLEPIF-SSEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINV 1290
Query: 1553 TSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVS 1612
S + + L K L + +K L+EYLETKR AFPRFYF+S +LL+ILS DP V
Sbjct: 1291 CSDLRMLDSLRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQ 1350
Query: 1613 RHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDR 1672
HL K F+++ +L F+ D L++ MYS E E + S VE WL V
Sbjct: 1351 PHLRKCFENIARLLFQED-----LEI-THMYSAEGEEVQLCFSIYPSSNVEDWLREVERS 1404
Query: 1673 MCSTLRHEIPEAVVTYEEKPREQWILDYPAQVALTCTQIWWTTEVGLAFARLEEGYENAI 1732
M +++ I +A+ Y PR QW+L++P QV + Q +WT EV A LE G N
Sbjct: 1405 MKASVHDIIEKAIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEA---LEAG--NLR 1459
Query: 1733 RDYNKKQISQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIVAKVESSQAFTW 1792
+ QL+ L+ L+ G L+ R + + I+VHA+DVV+K+I V S F W
Sbjct: 1460 SQLFPQLCQQLSDLVALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQW 1519
Query: 1793 QAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGG 1852
+QLR+ W + A +A+ Y YEYLGN+ RLVITPLTDRCY+TLT +LHL GG
Sbjct: 1520 ISQLRYYWTNNDLYIRA--VNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGG 1577
Query: 1853 APAGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNR 1912
APAGPAGTGKTETTKDLG+AL VFNCS+Q+D+ + G +KGLA GAW CFDEFNR
Sbjct: 1578 APAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNR 1637
Query: 1913 ISVEVLSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENL 1972
I +EVLSV+A Q+ +Q A + + + F F G I L+P+ +FITMNPGYAGR ELP+NL
Sbjct: 1638 IDIEVLSVVAQQITTIQKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNL 1697
Query: 1973 KALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRA 2032
KALFRP AM+VPD+ +I EI L + GF EA +LA+K T + L E LS QDHYD+G+RA
Sbjct: 1698 KALFRPVAMMVPDYAMITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRA 1757
Query: 2033 IKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRK 2092
+K+V+ AG+LKR +PS E+ + +RA+RD N+PK + +DL +F G++ DLFP + ++
Sbjct: 1758 VKTVISAAGNLKRENPSMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTI---KE 1814
Query: 2093 RDLNF---EKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKS 2149
D ++ ++ I+++ L+ + F+ K +QL E VRH + +VG GSGKS +
Sbjct: 1815 EDTDYGILDEAIREACRNSNLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRV 1874
Query: 2150 LNKTYQNLKRKP-------VAVD---LDPKAVTCDELFGIINPVTREWKDGLFSTIMRDL 2199
L +LK +P AV+ L+PK++T +L+G + +T EW DG+FS+ +R
Sbjct: 1875 LAAAMTSLKGQPSISGGMYEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAG 1934
Query: 2200 ANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRT 2259
A + KW + DG +D +WIE++NTV+DDNK L L+S E I L M ++FE+ L
Sbjct: 1935 AITSDTNKKWYMFDGPVDAIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAV 1994
Query: 2260 ATPATVSRAGILYINPADLGWNPVVSSWIERRK--VQSEKANLMILFDKYLPTCLDKLRF 2317
A+PATVSR G++Y+ P+ LG P + W+ + ++ + + LF +L + +R
Sbjct: 1995 ASPATVSRCGMVYLEPSILGLMPFIECWLRKLPPLLKPYEEHFKALFVSFLEESISFVRS 2054
Query: 2318 GFKKITPVPEITVIQTILYLLECLLTE-------KTVPPDSPR---ELYELYFVFTCFWA 2367
K++ + ++L LL+C K +P + EL E +F+F+ W+
Sbjct: 2055 SVKEVIASTNCNLTMSLLKLLDCFFKPFLPREGLKKIPSEKLSRIVELIEPWFIFSLIWS 2114
Query: 2368 FGGAMFQDQLVDYRVEFSKW----WINEFKTIKFPSQGTIFDYYIDP-------DTK--- 2413
G R FS W NE T+ FP +G +FDY ++ D++
Sbjct: 2115 VGATGDSSG----RTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLEDAGISGTNDSEDEE 2170
Query: 2414 ------KFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAG 2467
++ W D F + PD +V T +T+++ + +D+L+ PV+ +G G
Sbjct: 2171 EEYKQVAWVKWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPTG 2230
Query: 2468 TGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLV 2527
TGK++ + DKL +Y+ + F+ T++ Q ++ L+K+ +GPP + +
Sbjct: 2231 TGKTLTISDKLLKNLALDYISHFLTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRNFI 2290
Query: 2528 YFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKL-TLKDIHNCQYVACMNPTSGS- 2585
+FIDD+NMP ++ YG P L+RQ MDH WYDR + K++ + +V M P G
Sbjct: 2291 FFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGR 2350
Query: 2586 FTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHL-------AFRS---VSMAIQRISS 2635
T+ RL RHF + + + + I++TIL L ++R + I +
Sbjct: 2351 NTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFTE 2410
Query: 2636 QLVAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLH 2695
LV A + ++ IT+ LPT K HY FNLRDLS +FQG+L + ++ + L+RLW H
Sbjct: 2411 PLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYH 2470
Query: 2696 ETERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPK-YV 2754
E RV+ D++V+E+D+ ++ +++ F +P ++ F D K Y
Sbjct: 2471 ENCRVFRDRLVNEEDRSWFDQLLKRCMEQWEVTFNKVCPF-QPILYGDFMSPGSDVKSYE 2529
Query: 2755 PVTDMAPLNKLLVDVLDSYNEVN-AVMNLVLFEDAVAHICRINRILESPRGNALLVGVGG 2813
+T + + +++ + ++ YN++N A + LVLF DA++HICRI+R L GNALL+GVGG
Sbjct: 2530 LITSESKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLRQALGNALLLGVGG 2589
Query: 2814 SGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVA 2873
SG+ SL+RLA++++ + FQI L K YG+ + + D+ +KA ++N+P FL +D+Q+
Sbjct: 2590 SGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIK 2649
Query: 2874 EEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQ 2933
E FL IN++L SG+IP L+ DE + I+S+MRP ++ G+ T+ + +VR
Sbjct: 2650 NESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPTKANLMAAYTGRVRSN 2709
Query: 2934 LKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPVIKA 2993
+ ++LC SP+G V R R R+FP++VNC IDWF+EWP +AL SV+ FL E + +
Sbjct: 2710 IHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNEIPELESSQE 2769
Query: 2994 SISFFMS---YVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKI 3050
I + Y+H +V++ YLA R+NY TPK++LE + ++ L+ +K+ EL
Sbjct: 2770 EIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAK 2829
Query: 3051 ERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIAD 3110
R+++GL KL T+ V ++ L L++ + ++ + ++ + +
Sbjct: 2830 NRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQ 2889
Query: 3111 QEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVV 3170
EE+K K + DL +A PAL AA +L LNKN++TE+++ PP V
Sbjct: 2890 TEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVK 2949
Query: 3171 NVTAAVMILTA----------PGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEA 3220
V AV I+ PG K+ D W+ K ++ FL+SL KFDK++I +
Sbjct: 2950 LVIEAVCIMKGIKPKKVPGEKPGTKV--DDYWEPGKGLLQDPGHFLESLFKFDKDNIGDV 3007
Query: 3221 CLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAEL 3280
+KA +PY N F P I S A +C W + +++ V V PKRQAL EA +L
Sbjct: 3008 VIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDL 3067
Query: 3281 AEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLA 3340
Q L K ++ E+ ++ + + + + +K + + + + + + A +L+ GL+
Sbjct: 3068 GVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKLINGLS 3127
Query: 3341 SENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYI--HNLK 3398
E +RW E+VEN + + GDVL+ + FV+Y+G FT +YR L + W+ + HN
Sbjct: 3128 DEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDS-WVKQLRSHN-- 3184
Query: 3399 VPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIK 3458
+P T+ + L + + +W GLP+D +S EN I ++RW +D Q Q K
Sbjct: 3185 --VPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQANK 3242
Query: 3459 WIKNKYRSE-LKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKK- 3516
WIKN + L +L + +L +E AI G L+EN+GE +DP L+P+L + T K+
Sbjct: 3243 WIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQ 3302
Query: 3517 -GKYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVV 3575
+K+GD + YH FR+ + TK NPHY PE+ + TLINF ++ GLEDQLL VV
Sbjct: 3303 GNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVV 3362
Query: 3576 AKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTA 3635
A+ERPDLE+ K L S + + LK++ED +L RLS++ GN + D L++ LE +K A
Sbjct: 3363 AEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKA 3422
Query: 3636 SEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFE 3695
+EI+ KV A+ TE I+ R Y P A R +L+F ++DL ++P+YQ+SL+ F +F
Sbjct: 3423 AEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIFL 3482
Query: 3696 KAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNP 3755
I + A+ +K+R+ N+ +TYS+Y R LFE+ KL+F + +++ + ++N
Sbjct: 3483 SGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQ 3542
Query: 3756 VELDFLLRFPFKAGVVSPV------DFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWK 3809
E +LL G +S + D+L + W I ALS + F + SD ++
Sbjct: 3543 SEWRYLL----SGGSISIMTENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFR 3598
Query: 3810 KLVESEAPEKEIFPKEW-KNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSV 3868
+ +S P +E P W + QKL ++RCLR D++T A+++FV + +F+E ++
Sbjct: 3599 VIFDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTA 3658
Query: 3869 EFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAEN 3928
S +++S+ +T + F+LSPG DP D+ +++ F + KL +SLGQGQ AE
Sbjct: 3659 NLSVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKF---SKKLSAISLGQGQGPRAEA 3715
Query: 3929 ALDVAAEKGHWVILQNIHLVARWLGTLDKKLERYSTGS-HEDYRVFISAEPAPSPETHII 3987
+ + E+G WV QN HL W+ L++ +E + H D+R+++++ P ++
Sbjct: 3716 MMRSSIERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLP-----SNKF 3770
Query: 3988 PQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAE 4047
P IL+N K+T EPP G+ ANL K+ +D L C K MEFK +L +LC FH E
Sbjct: 3771 PVSILQNGSKMTIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALE 3830
Query: 4048 RRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWD 4107
RRKFG G+N Y F +GDL I I+ L +L+ +P+ L+Y GEI YGG +TDDWD
Sbjct: 3831 RRKFGPLGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWD 3890
Query: 4108 RRLCRTYLAEYIRTEMLEGDVLLAPG---FQIPPNLDYKGYHEYIDENLPPESPYLYGLH 4164
RR L ++ ++L + + QIPP D GY YI + P ++GLH
Sbjct: 3891 RRCIMNILEDFYNPDVLSPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLH 3950
Query: 4165 PNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKVKAVLDDILEKIPETFNMAE 4224
NA I F + L T++++QPK + +G+ REE V+ V +IL K+PE N+
Sbjct: 3951 DNANITFAQNETFALLGTIIQLQPKSSSAGS---QGREEIVEDVTQNILLKVPEPINLQW 4007
Query: 4225 IMAK--AAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALF 4282
+MAK + V QE R N L + ++L++L LKG + +++ +E ++ +L+
Sbjct: 4008 VMAKYPVLYEESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLY 4067
Query: 4283 YDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTA 4342
+TVP+ W A+AYPS+ L++W DLL R+ L+AW D +P W++GFF PQ+FLT
Sbjct: 4068 NNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQD-GIPAVFWISGFFFPQAFLTG 4126
Query: 4343 IMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEA 4402
+Q+ ARK +D + +V + ++T P+ G Y++GLF+EGARWD + +AE+
Sbjct: 4127 TLQNFARKFVISIDTISFDFKVMFEAPSELTQRPQVGCYIHGLFLEGARWDPEAFQLAES 4186
Query: 4403 RLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPT---------YVWTFNLKTK 4453
+ KEL M VI++ P + + ++ Y CP+YKT R T YV + T
Sbjct: 4187 QPKELYTEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTH 4246
Query: 4454 EKAAKWILAAVALL 4467
+ WI VAL+
Sbjct: 4247 QPQRHWIKRGVALI 4260
>gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens]
Length = 4024
Score = 1980 bits (5129), Expect = 0.0
Identities = 1223/3695 (33%), Positives = 1948/3695 (52%), Gaps = 202/3695 (5%)
Query: 906 PLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRL-----AKDRMN 960
P F +R+ LD D + F P L D FL + + ++ + V R+ +L +K +
Sbjct: 400 PGFIMRLILDNDTIKFEPELSDYIDI-FLNVYDVMIKAVSFVPRVETKLYSKWESKSKPT 458
Query: 961 YKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCA 1020
+ N + +E++ +++ E+ +++Y +L T + + NFL
Sbjct: 459 TLKPIILNEIVDAHKEKIKEVIMKESVAPTEHLRLYDKYDFLITRKAERDVDNFL----- 513
Query: 1021 VTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQ 1080
AE+ + + ++I Y+KL EE+ + G + C +
Sbjct: 514 --AEN-------------HSYEKIIDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELIR 558
Query: 1081 ALLSTI-----RRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVM 1135
AL+ + MF+ H V L D F ++A L+ P + L+E+
Sbjct: 559 ALVKRADIICGKLLAKMFRDH--QEVNTRLCD--EFERIAEKALSTPPNTAE---LMEMK 611
Query: 1136 GHLMKVKERQAAT-DNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQV 1194
++ KV+ + K + L Y P ++ L + +
Sbjct: 612 AYIQKVEVTDMIELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWYGRMGEIFEEHR 671
Query: 1195 KLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKQQKSISAM 1254
K+ ++ + L+ +C++F + + ++ E +SF D + + + K +
Sbjct: 672 KIIKEKIEQYQEG-LKLRCERFVEELESYAKQ--SEEFYSFGD---LQDVQRYLKKAQIL 725
Query: 1255 EGIMEALSKSGGLFEVPVPDYKQLKACHREVRLLKE-------LWDMVVVVNTSIEDWKT 1307
G ++ + F + L + + + + +++ L++ V +++ W
Sbjct: 726 NGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNYRAWTE 785
Query: 1308 TKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRA----VSELQ 1363
+ +N +Q++ D + + + L+K + + V++ + + + +
Sbjct: 786 GPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVIC 845
Query: 1364 NPAIRERHWQQLMQATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVL 1423
NP +R RHW+ + + S+++T++ L +NL Y D I + A KE +EK +
Sbjct: 846 NPGLRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAM 905
Query: 1424 KALDSTWSMMEFQHEPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTS 1483
+ + + W +EF + TGT +L S + + L+D+ ++ Q + S ++ + K++
Sbjct: 906 EKMITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMRE 965
Query: 1484 WQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDA 1543
W+ KL ++ W +VQ TW +LE IF S DI +Q+P + +RF +++ ++ +M
Sbjct: 966 WEGKLLLLQEILDEWLKVQATWLYLEPIF-SSPDIMSQMPEEGRRFTAVDKTWRDIMRSV 1024
Query: 1544 VKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILS 1603
++ +V+ + + +L+ + L + K L EYLE KRL FPRF+F+S+ +LL+ILS
Sbjct: 1025 MQDKHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILS 1084
Query: 1604 NGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVE 1663
DP V HL K F+ + K++F +K G + E + GQVE
Sbjct: 1085 ETKDPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSEG---EVVELIEIISTAKARGQVE 1141
Query: 1664 VWLNRVLDRMCSTLRHEIPEAVVTYEEKPREQWILDYPAQVALTCTQIWWTTEVGLAFAR 1723
WL + M +++ +A Y + R W+ D+P Q L +QI+WT EV A
Sbjct: 1142 KWLVELERVMINSIHKVTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAIPM 1201
Query: 1724 LEEGYENAIRDYNKKQISQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIVAK 1783
+ E ++ N+ Q++ ++TL+ G L+ +R+ + + +DVHARDV++ ++
Sbjct: 1202 GIKALEQYLKTCNR----QIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKN 1257
Query: 1784 VESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLT 1843
+ F W +QLR+ W E H + +A ++Y YEYLGN+PRLVITPLTDRCY TL
Sbjct: 1258 ISDDSDFEWLSQLRYYWQEN--HLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLF 1315
Query: 1844 QSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGA 1903
+LHL +GGAP GPAGTGKTETTKDL +A+ VFNCS+ +DY + G +KGL GA
Sbjct: 1316 GALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGA 1375
Query: 1904 WGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYA 1963
W CFDEFNRI +EVLSV+A Q+ +Q I A F G + L PT +FITMNPGYA
Sbjct: 1376 WACFDEFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFITMNPGYA 1435
Query: 1964 GRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQ 2023
GR+ELP+NLKALFR AM+VPD+ +I EI+L + GF+ AR L+ K + Y LC E LS Q
Sbjct: 1436 GRSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQ 1495
Query: 2024 DHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDL 2083
HYD+G+RA+KSVL AG+LK P+ E+ +L+R++ D N+PK ++ DLP+F G+ DL
Sbjct: 1496 HHYDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDL 1555
Query: 2084 FPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGK 2143
FP + +P+ + IK + + LQ F K++Q+ E++ VRH IVG GK
Sbjct: 1556 FPGVKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGK 1615
Query: 2144 SQVLKSLNKTYQNLKRKPVAVD-------LDPKAVTCDELFGIINPVTREWKDGLFSTIM 2196
+ + L ++ K + + L+PK+VT +L+G + V+ EW DG+ +
Sbjct: 1616 TSAYRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSF 1675
Query: 2197 RDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISH 2256
R A+ KW+I DG +D +WIE++NTV+DDNK L L S E I ++ M L+FE
Sbjct: 1676 RAFASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMD 1735
Query: 2257 LRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQ---SEKANLMILFDKYLPTCLD 2313
L A+PATVSR G++Y+ P LGW P++ SW+ +K +M LFD+ +P ++
Sbjct: 1736 LEVASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVE 1795
Query: 2314 KLRFGFKKITPVPEITVIQTILYLLECLL----TEKTVPPDSPRELYEL---YFVFTCFW 2366
+R K+++P + ++++++ L++C + E + + RE Y L F+F+ W
Sbjct: 1796 FIRKHTKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEGIFLFSLIW 1855
Query: 2367 AFGGAMFQDQLVDY--------RVEFSKWWINEFK-------------TIKFPSQGTIFD 2405
+ G + D + + S N FK T+ FP +GTI+D
Sbjct: 1856 SVGASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYD 1915
Query: 2406 Y-YIDPDTKKFLPWTDKVPSFELDP-DVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLV 2463
Y ++ K+ PW K+ P DV +V T +TIR M+LL P + V
Sbjct: 1916 YQFVTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFV 1975
Query: 2464 GNAGTGKSVLMGD-KLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPG 2522
G GTGKSV + + L LN + Y + F+ TT+A Q ++ L+K+ +GPP
Sbjct: 1976 GPTGTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPL 2035
Query: 2523 TKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPT 2582
K++V F+DD+NMP + YG P L+RQ +DH +WYD ++ + + Q + M P
Sbjct: 2036 GKRMVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPP 2095
Query: 2583 SGSFT-IDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAF-RSVSMAIQRISSQLVAA 2640
G + R RHF + ++ +++ TI++ ILT HL +++Q+V
Sbjct: 2096 GGGRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNG 2155
Query: 2641 ALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERV 2700
+ L+++ LPT K HY+FNLRD S + QG+ S E +T + RLW+HE RV
Sbjct: 2156 TMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRV 2215
Query: 2701 YGDKMVDEKDQETLHRVTMASTKKF----FDDLGDELLF----------AKPNIFCHFAQ 2746
Y D+++D D+ L + + F +L L F + +FC F
Sbjct: 2216 YYDRLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDF-- 2273
Query: 2747 GIGDPK-----YVPVTDMAPLNKLLVDVLDSYNEVN-AVMNLVLFEDAVAHICRINRILE 2800
DPK Y + D+ L ++ L+ YN ++ MNLVLF A+ HI RI+RIL+
Sbjct: 2274 --HDPKREDTNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILK 2331
Query: 2801 SPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKN 2860
PR +ALLVGVGGSG+QS++RLAA+++ VFQ+ + KGY + DL K A
Sbjct: 2332 QPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGE 2391
Query: 2861 VPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSM----RPQVKSLGMN 2916
+ VFL TD+Q+ EE FL +++LL +GEIP LF DE + I M R + K+ +
Sbjct: 2392 MQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTD 2451
Query: 2917 DTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVS 2976
+ + FI+ R QL V+L SP+G R R RKFPA+VNC IDWF WPEDAL +
Sbjct: 2452 GSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQA 2511
Query: 2977 VSARFLEETEGIPVIKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQ 3036
V++RFLEE E I+ HT+ ++S+ + +RYNY TP ++LE I ++
Sbjct: 2512 VASRFLEEIEMSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFK 2571
Query: 3037 NLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVG 3096
LL KKR+E++ +R E GL KL S +SQV ++ +L +LK ++ D+++ ++
Sbjct: 2572 LLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIE 2631
Query: 3097 IEAEKVSK-EKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNN 3155
E+ +V+K EK + E + E + K + C+ DLA A P L +A ALDTL +
Sbjct: 2632 KESVEVAKTEKIVKADETIANEQAMASKAIKDE-CDADLAGALPILESALAALDTLTAQD 2690
Query: 3156 LTELKSFGSPPDAVVNVTAAVMIL-----------TAPGGKIPKDKSWKAAKIMMGKVDT 3204
+T +KS SPP V V A+ IL T G KI + W AK ++G +
Sbjct: 2691 ITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKI--EDFWGPAKRLLGDM-R 2747
Query: 3205 FLDSLKKFDKEHIPEACLKAF-KPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVY 3263
FL SL ++DK++IP A + K Y NP F PE IR+ STAA GLC W I + + +V
Sbjct: 2748 FLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVA 2807
Query: 3264 CDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEAD 3323
VAPK+ L A EL A + L + + + E+ L+ L E +K + + D
Sbjct: 2808 KIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVD 2867
Query: 3324 ATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRN 3383
++ + A +L+GGL E RW+ + + L GD+L+ S V+Y+G FT YR
Sbjct: 2868 LCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQ 2927
Query: 3384 ELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNT 3443
K W IP ++ + L + + TWN GLPSD S +N I+ N
Sbjct: 2928 N-QTKEWTTLCKGR--DIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNA 2984
Query: 3444 ERWPLIVDAQLQGIKWIKNKYR-SELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVD 3502
RWPL++D Q Q KWIKN + + L I+L + Y+ +E I G +L+EN+GE +D
Sbjct: 2985 RRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELD 3044
Query: 3503 PVLDPLLGRNTIKKG--KYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFL 3560
P+L+PLL + T K+G I++GD +EY P FR + TK NPHY PE + TL+NF+
Sbjct: 3045 PILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFM 3104
Query: 3561 VTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLG 3620
+T +G++DQLL VVA+ERPDLE+ K L E K LKE+ED +L LS++ GN L
Sbjct: 3105 ITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILE 3164
Query: 3621 DTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKIN 3680
D ++ L ++K A+EI +K A+ TE KI+ R YRP A +S+L+F L DL I
Sbjct: 3165 DETAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIE 3224
Query: 3681 PVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLA 3740
P+YQ+SL F +F +I+ + + + +R+ L D TYS+Y+ R LFE+DKL+F
Sbjct: 3225 PMYQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSF 3284
Query: 3741 QVTFQVLSMKKELNPVELDFLLRFPFKAGVVSP----VDFLQHQGWGGIKALSEMDEFKN 3796
+T +L ++ +N E FLL G+ +P +L + W I L ++ FK
Sbjct: 3285 CLTINLLLHERAINKAEWRFLLTGGI--GLDNPYANLCTWLPQKSWDEICRLDDLPAFKT 3342
Query: 3797 LDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNK-TALQKLCMVRCLRPDRMTYAIKNFVE 3855
+ + WKK+ +S P E+FP+EW++K Q++ ++RCLRPD++ ++ F+
Sbjct: 3343 IRREFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFII 3402
Query: 3856 EKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHN 3915
++G F+E + +K++ +S+ + F+LSPG DP+ + G+ KL +
Sbjct: 3403 NRLGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQGY--GGSKLSS 3460
Query: 3916 VSLGQGQEVVAENALDVAAEKGHWVILQNIHLVARWLGTLDKKLERYSTGS-HEDYRVFI 3974
+SLGQGQ +A L+ A ++G WV+LQN HL W+ TL+K E S S H D+R+++
Sbjct: 3461 LSLGQGQGPIAMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWL 3520
Query: 3975 SAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKAL---DLFTQDTLEMCTKEMEF 4031
++ P+P+ P +L+N +K+TNE P G+ AN+ ++ + + C K EF
Sbjct: 3521 TSYPSPN-----FPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSCKKPEEF 3575
Query: 4032 KCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRY 4091
K +L+ LC+FHA+V ERRKFG GWN Y FN DL IS+ L+ +L ++P++ LRY
Sbjct: 3576 KKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYEELPYEALRY 3635
Query: 4092 LFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPG---FQIPPNLDYKGYHEY 4148
+ GE YGG +TDDWDRR R+ L ++ E++E + +PP+ D+K Y EY
Sbjct: 3636 MTGECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYFVPPSGDHKSYIEY 3695
Query: 4149 IDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKVKAV 4208
+P ++G++ NA+I ++ LF +L Q + +GA S +E V V
Sbjct: 3696 TKTLPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSRSAGAGA---KSSDEVVNEV 3752
Query: 4209 LDDILEKIPETFNMAEIMAKAAEKTPYV----VVAFQECERMNILTNEMRRSLKELNLGL 4264
DIL K+P F++ M + T Y V QE R N L +R S + +
Sbjct: 3753 ASDILGKLPNNFDIEAAMRR--YPTTYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAI 3810
Query: 4265 KGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFAL 4324
KG ++TD+E++ +++ +P+ W+ ++YPS+ L ++ D L R++ L+ W +
Sbjct: 3811 KGLAVMSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQW-YEVGP 3869
Query: 4325 PTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYG 4384
P WL+GFF Q+FLT Q+ ARK P+D + EV + ++ PP +G +++G
Sbjct: 3870 PPVFWLSGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYEVMED--KEYKHPPEDGVFIHG 3927
Query: 4385 LFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIR---- 4440
LF++GA W+ + +AE+ K L +PV+++K + + Y P+YKT R
Sbjct: 3928 LFLDGASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVL 3987
Query: 4441 -----GPTYVWTFNLKTKEKAAKWILAAVALLLQV 4470
+V L + + WI VALL Q+
Sbjct: 3988 STTGHSTNFVIAMTLPSDQPKEHWIGRGVALLCQL 4022
>gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]
Length = 4624
Score = 1950 bits (5051), Expect = 0.0
Identities = 1193/3613 (33%), Positives = 1935/3613 (53%), Gaps = 152/3613 (4%)
Query: 938 EGLVNDIYNVARLIPRLAKDRMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFE 997
E + D +A + + NY ++ +N +++++ +S+++ + KE D F+
Sbjct: 1083 ENELQDTLEIASVNLPIPVQTKNYYKNVSENKEIVKLVSVLSTIINSTKKEVITSMDCFK 1142
Query: 998 RYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEE 1057
RY+++W +E +K F+ P L++F+ QI ++ L +E
Sbjct: 1143 RYNHIWQKGKEEAIKTFITQS--------------------PLLSEFESQILYFQNLEQE 1182
Query: 1058 VSKCENTKVFHGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARM 1117
++ E V G + K AL + + W + RH + + + ++ ++
Sbjct: 1183 IN-AEPEYVCVGSIALYTADLKFALTAETKAWMVVIGRHCNKKYRSEMENIFMLIEEFNK 1241
Query: 1118 GLTKPLKEGDYDGLVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKL 1177
L +P+K D D + M L +++E Q + D P++++ LL YG + E K+
Sbjct: 1242 KLNRPIK--DLDDIRIAMAALKEIREEQISIDFQVGPIEESYALLNRYGLLIAREEIDKV 1299
Query: 1178 QELPEHWANTKKLAIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSD 1237
L W A +V+ + LQ + L + F H+F + P + S
Sbjct: 1300 DTLHYAWEKLLARAGEVQNKLVSLQPSFKKELISAVEVFLQDCHQFYLDYDLNGPMA-SG 1358
Query: 1238 PNPYKSLNKQQKSISAMEGIMEA-LSKSGG--LFEVPVPDYKQLKACHREVRLLKELWDM 1294
P ++ ++ + + I ++ +GG LF +P Y QL +++ LL++++ +
Sbjct: 1359 LKPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPATQYPQLLEIKKQLNLLQKIYTL 1418
Query: 1295 VVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVIT 1354
V ++ + W ++N+E+++ + +F R L + +K W AF+ L + +
Sbjct: 1419 YNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRALKDWQAFLDLKKIIDDFSE 1478
Query: 1355 SLRAVSELQNPAIRERHWQQLMQATQVKFKMSEET-TLADLLQLNLHSYEDEVRNIVDKA 1413
+ + + A+ ERHW+++ T + E+ L ++++ L Y++E+ +I A
Sbjct: 1479 CCPLLEYMASKAMMERHWERITTLTGHSLDVGNESFKLRNIMEAPLLKYKEEIEDICISA 1538
Query: 1414 VKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLK--SSEVLVETLEDNQVQLQNLMMS 1471
VKE +E+ LK + + W F G ++L+ S+ ++ +ED+ + L +L+ +
Sbjct: 1539 VKERDIEQKLKQVINEWDNKTFTFGSFKTRGELLLRGDSTSEIIANMEDSLMLLGSLLSN 1598
Query: 1472 KYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDD 1531
+Y F ++ W Q LS + +I W VQ W +LE++F+G DI QLP +++RF +
Sbjct: 1599 RYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEAVFVGG-DIAKQLPKEAKRFSN 1657
Query: 1532 INQEFKALMEDAVKTPNVVEA-TSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPRF 1590
I++ + +M A + P+VV+ L L L L IC+K+L YLE KRL FPRF
Sbjct: 1658 IDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHLLDQLEICQKSLTGYLEKKRLCFPRF 1717
Query: 1591 YFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYM 1650
+FVS LL+IL +D + HL +FD++ +KF D+ L + S+E E +
Sbjct: 1718 FFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVKFHEKIYDRILSIS----SQEGETI 1773
Query: 1651 VFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPRE--QWILDYPAQVALTC 1708
D+ G VEVWLN +L+ S+L I +A +E + +++ +PAQV L
Sbjct: 1774 ELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQETGFQLTEFLSSFPAQVGLLG 1833
Query: 1709 TQIWWT--TEVGLAFARLEEGYENAIRDYNKKQISQLNVLITLLMGNLNAGDRMKIMTIC 1766
Q+ WT +E L A+ ++ ++ N+ + LN LI + +L++ +R+K T+
Sbjct: 1834 IQMIWTRDSEEALRNAKFDK---KIMQKTNQAFLELLNTLIDVTTRDLSSTERVKYETLI 1890
Query: 1767 TIDVHARDVVAKMIVAKVESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNT 1826
TI VH RD+ + ++S F W Q R ++E+ +I D Y E+LG T
Sbjct: 1891 TIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSDKMMIHITDVAFIYQNEFLGCT 1950
Query: 1827 PRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQM 1886
RLVITPLTDRCYITL Q+L + MGGAPAGPAGTGKTETTKD+GR LG V VFNCS+QM
Sbjct: 1951 DRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQM 2010
Query: 1887 DYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFL-GEI 1945
D++ G I+KGLAQ+G+WGCFDEFNRI + VLSV A Q+ + + KK+F F G+
Sbjct: 2011 DFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSFIFTDGDN 2070
Query: 1946 IGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLL 2005
+ + P G+F+TMNPGYAGR ELPENLK FR AM+VPD ++I + L + GF++ +L
Sbjct: 2071 VTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNVVL 2130
Query: 2006 ARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNI 2065
ARKF TLY LC+E LSKQ HYD+GLR I SVL G+ KR +P E ++MR LRD N+
Sbjct: 2131 ARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPMDTESTIVMRVLRDMNL 2190
Query: 2066 PKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEE 2125
K++ +D P+F+ LI DLFP + + + E I + + E L + LKV+QL E
Sbjct: 2191 SKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQVEEAGLINHPPWKLKVIQLFE 2250
Query: 2126 LLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPVTR 2185
+VRH + +G +G+GK+ + +L + + + + ++PKA+T ++FG ++ T
Sbjct: 2251 TQRVRHGMMTLGPSGAGKTTCIHTLMRAMTDCGKPHREMRMNPKAITAPQMFGRLDVATN 2310
Query: 2186 EWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLN 2245
+W DG+FST+ R WIILDG +D +WIE+LN+V+DDNK LTLA+ +RIP+
Sbjct: 2311 DWTDGIFSTLWRKTLRAKKGEHIWIILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMA 2370
Query: 2246 RTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMILFD 2305
+++FE ++ A+PATVSR G+++++ + L W+P++ ++++R Q + IL
Sbjct: 2371 PNCKIIFEPHNIDNASPATVSRNGMVFMSSSILDWSPILEGFLKKRSPQEAE----ILRQ 2426
Query: 2306 KYLPTCLDKLRFGFKKI---TPVPEITVIQTILYLLECLLTEKTVPPDSPRELYELYFVF 2362
Y + D RF + + V E VI + +L+ L+ K + + FVF
Sbjct: 2427 LYTESFPDLYRFCIQNLEYKMEVLEAFVITQSINMLQGLIPLKEQGGEVSQAHLGRLFVF 2486
Query: 2363 TCFWAFGGAMFQDQLVDYRVEFSKWWINE-FKTIKFPSQG----TIFDYYIDPD------ 2411
W+ G A+ +D R W + T++ P T FDYY+ PD
Sbjct: 2487 ALLWSAGAAL----ELDGRRRLELWLRSRPTGTLELPPPAGPGDTAFDYYVAPDGTWTHW 2542
Query: 2412 ---TKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGT 2468
T+++L +D P + + LV + +R + + + ++ V+L+G GT
Sbjct: 2543 NTRTQEYLYPSDTTPEY--------GSILVPNVDNVRTDFLIQTIAKQGKAVLLIGEQGT 2594
Query: 2469 GKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVY 2528
K+V++ + + + ++++++ F+ TT M Q +E ++K+ G YGPP KK+
Sbjct: 2595 AKTVIIKGFMSKYDPECHMIKSLNFSSATTPLMFQRTIESYVDKRMGTTYGPPAGKKMTV 2654
Query: 2529 FIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKL-TLKDIHNCQYVACM-NPTSGSF 2586
FIDD+NMP ++++G + ++RQ M+ +Y+ K I + Q++A M +P G
Sbjct: 2655 FIDDVNMPIINEWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDIQFLAAMIHPGGGRN 2714
Query: 2587 TIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAF-RSVSMAIQRISSQLVAAALALH 2645
I RL+R F +F + P + ++ I+ I H R S ++ ++LV L
Sbjct: 2715 DIPQRLKRQFSIFNCTLPSEASVDKIFGVIGVGHYCTQRGFSEEVRDSVTKLVPLTRRLW 2774
Query: 2646 QKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKM 2705
Q LPT KFHYVFNLRDLS ++QG+L +T+EV+K P DL++LW HE +RV D+
Sbjct: 2775 QMTKIKMLPTPAKFHYVFNLRDLSRVWQGMLNTTSEVIKEPNDLLKLWKHECKRVIADRF 2834
Query: 2706 VDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGD--------------- 2750
D + ++ ++ F + ++ L I +F + D
Sbjct: 2835 TVSSDVTWFDKALVSLVEEEFGE--EKKLLVDCGIDTYFVDFLRDAPEAAGETSEEADAE 2892
Query: 2751 -PK-YVPVTDMAPLNKLLVDVLDSYNEV--NAVMNLVLFEDAVAHICRINRILESPRGNA 2806
PK Y P+ + L + L L YNE A M++V F DA+ H+ +I+R++ +P+GNA
Sbjct: 2893 TPKIYEPIESFSHLKERLNMFLQLYNESIRGAGMDMVFFADAMVHLVKISRVIRTPQGNA 2952
Query: 2807 LLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFL 2866
LLVGVGGSGKQSL+RLA++I+G FQITL + Y +L DL Y A + F+
Sbjct: 2953 LLVGVGGSGKQSLTRLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFI 3012
Query: 2867 MTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMN--DTRETCWK 2924
TD+++ +E FL +N++L+SGE+ LF DE++ I S + +K T E
Sbjct: 3013 FTDNEIKDESFLEYMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEFPRCLPTNENLHD 3072
Query: 2925 FFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLE- 2983
+F+ +VR+ L ++LCFSPVG R RA KFPA+++ IDWF WP+DALV+VS FL
Sbjct: 3073 YFMSRVRQNLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVSEHFLTS 3132
Query: 2984 -ETEGIPVIKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKK 3042
+ + IK + M V E Y RR + TPK++L I+ Y+ + +K
Sbjct: 3133 YDIDCSLEIKKEVVQCMGSFQDGVAEKCVDYFQRFRRSTHVTPKSYLSFIQGYKFIYGEK 3192
Query: 3043 RTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKV 3102
E+ R+ GL KL+ + V L +L +E EL+ N+ AD +++ V ++A+
Sbjct: 3193 HVEVRTLANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQAA 3252
Query: 3103 SKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSF 3162
K KA + + + + I ++++ + E L A+PAL A+ AL T+ +++ +++
Sbjct: 3253 EKVKAEVQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTL 3312
Query: 3163 GSPPDAVVNVTAAVMIL---TAPGGKIPKDK-----SWKAAKIMMGKVDTFLDSLKKFDK 3214
G PP ++ + V++L KI +K SW+ + +M FL +L++F K
Sbjct: 3313 GRPPHLIMRIMDCVLLLFQRKVSAVKIDLEKSCTMPSWQESLKLM-TAGNFLQNLQQFPK 3371
Query: 3215 EHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALE 3274
+ I E ++ PY P ++ E + AGLCSW + F+ + +V P + L
Sbjct: 3372 DTINEEVIEFLSPYFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLV 3431
Query: 3275 EANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANR 3334
A + L + + ++ + A L + + +E+A EK ++A+ + A+
Sbjct: 3432 VQENRHLLAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQTAST 3491
Query: 3335 LVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYI 3394
L+ GLA E RW E + F +Q L GDVLL +AF+SY G F +++R+ L+ W +
Sbjct: 3492 LISGLAGEKERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLND-WRKEM 3550
Query: 3395 HNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQL 3454
K IP L+ +L D ++ WN QGLP+D +S +N I+ R+PL++D Q
Sbjct: 3551 KARK--IPFGKNLNLSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQT 3608
Query: 3455 QGIKWIKNK-YRSELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNT 3513
QG WIKNK R+EL+ L K + + +E ++S G LLIE++GE +DP LD +L RN
Sbjct: 3609 QGKIWIKNKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLERNF 3668
Query: 3514 IKKGK--YIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLL 3571
IK G +K+GDKEV+ FRL + TK NP Y PE+ A+ ++I+F VT GLEDQLL
Sbjct: 3669 IKTGSTFKVKVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLEDQLL 3728
Query: 3572 AAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETT 3631
V+ E+ +LE+ + +L + K +KELED+LL RL++ G+ + D +L+ L T
Sbjct: 3729 GRVILTEKQELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNT 3788
Query: 3632 KHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFN 3691
K TA E+ +K+ + TEV+IN ARE YRP A R S+LYF++ ++ +N +YQ SL+ F
Sbjct: 3789 KRTAEEVTQKLEISAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSLRQFL 3848
Query: 3692 VVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKK 3751
+F+ ++ R+ + +R+ N+ + +TY VY Y ARGL+E K +F +T ++ +
Sbjct: 3849 GLFDLSLARSVKSPITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRN 3908
Query: 3752 ELNPVELDFLLR----FPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKR 3807
+ E L++ KA P ++ W + LS++ +F ++ I + K
Sbjct: 3909 RVKHEEFLTLIKGGASLDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLDQISRNEKM 3968
Query: 3808 WKKLVESEAPEKEIFPKEW-KNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGR 3866
WK + E PE+E P + K+ ++L ++R PDR + ++ + MG K+ EG
Sbjct: 3969 WKIWFDKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAEGV 4028
Query: 3867 SVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVA 3926
++ K++EES P T + +LS G DP + ALGK+L + VS+GQGQEV A
Sbjct: 4029 ILDLEKTWEESDPRTPLICLLSMGSDPTDSIIALGKRLKI-----ETRYVSMGQGQEVHA 4083
Query: 3927 ENALDVAAEKGHWVILQNIHLVARWLGTL-DKKLERYSTGSHEDYRVFISAEPAPSPETH 3985
L G W +LQN HL ++ L D +E H+ +R++++ E
Sbjct: 4084 RKLLQQTMANGGWALLQNCHLGLDFMDELMDIIIETELV--HDAFRLWMTTEAHKQ---- 4137
Query: 3986 IIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVV 4045
P +L+ +IK N+PP G+ A L + +QD L++ + ++K ML+A+ + H+ V
Sbjct: 4138 -FPITLLQMSIKFANDPPQGLRAGLKRTYSGVSQDLLDV-SSGSQWKPMLYAVAFLHSTV 4195
Query: 4046 AERRKFGAQGWNRSYPFNNGDLTISINVLYNYL---EANPKVPWDDLRYLFGEIMYGGHI 4102
ERRKFGA GWN Y FN D ++ + N+L + V W +RY+ GEI YGG +
Sbjct: 4196 QERRKFGALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGRV 4255
Query: 4103 TDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYG 4162
TDD+D+RL T+ + M D G+ IP Y +YI +SP ++G
Sbjct: 4256 TDDYDKRLLNTFAKVWFSENMFGPDFSFYQGYNIPKCSTVDNYLQYIQSLPAYDSPEVFG 4315
Query: 4163 LHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKVKAVLDDILEKIPE---T 4219
LHPNA+I + + ++ + T+L +QPK+T G +RE V + DD+LEK+P
Sbjct: 4316 LHPNADITYQSKLAKDVLDTILGIQPKDTSGGGDE--TREAVVARLADDMLEKLPPDYVP 4373
Query: 4220 FNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLST 4279
F + E + K P + QE +RM + + +R +L EL L + G + ++ ++ D
Sbjct: 4374 FEVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDALD 4433
Query: 4280 ALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSF 4339
+F +P W ++ S L W+ +L+ R + +W + P W+ GFFNPQ F
Sbjct: 4434 CMFDARIPAWWKKASWISST-LGFWFTELIERNSQFTSWVFN-GRPHCFWMTGFFNPQGF 4491
Query: 4340 LTAIMQSMARKNE-WPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGV 4398
LTA+ Q + R N+ W LD M L EVTK ++D++APP EG YVYGL++EGA WD +
Sbjct: 4492 LTAMRQEITRANKGWALDNMVLCNEVTKWMKDDISAPPTEGVYVYGLYLEGAGWDKRNMK 4551
Query: 4399 IAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGP-TYVWTFNLKTKEKAA 4457
+ E++ K L MPVI I A + + Y CP+YK +R Y+ +L+T +
Sbjct: 4552 LIESKPKVLFELMPVIRIYA-ENNTLRDPRFYSCPIYKKPVRTDLNYIAAVDLRTAQTPE 4610
Query: 4458 KWILAAVALLLQV 4470
W+L VALL V
Sbjct: 4611 HWVLRGVALLCDV 4623
Score = 155 bits (391), Expect = 1e-36
Identities = 148/641 (23%), Positives = 283/641 (44%), Gaps = 67/641 (10%)
Query: 190 LHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKCIHEQLNRPK 249
L IE + W Q VL++++ Q L + P+ E E W RL + EQL P
Sbjct: 250 LGKIEDCMKVWIKQTEQVLAENN-QLLKEADDVGPRAELEHWKKRLSKFNYLLEQLKSPD 308
Query: 250 VNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEMEQADFTMLPT 309
V ++ +L AKS + + +T+ EA D V YL L + + +D +
Sbjct: 309 VKAVLAVLAAAKSKLLKTWREMDIRITDATNEAKDNVKYLYTLEKCCDPLYSSDPLSMMD 368
Query: 310 FIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLS----------PEEVL 359
I +++ I I++ S YYNT +I + + NQII + +++ P++V+
Sbjct: 369 AIPTLINAIKMIYSISHYYNTSEKITSLFVKVTNQIISACKAYITNNGTASIWNQPQDVV 428
Query: 360 KGLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFK-DKEPVPWEFPSSLAFSRIN 418
+ E++LS I +L Q Y C K K + ++F F +
Sbjct: 429 E------EKILSAI--------KLKQEYQLCFHKTKQKLKQNPNAKQFDFSEMYIFGKFE 474
Query: 419 SFFQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDP 478
+F +R+ I +++ T + L+ + G L + T+ Y + +K +Y+
Sbjct: 475 TFHRRLAKIIDIFTTLKTYSVLQDSTIEG-----LEDMATK-YQGIVATIK---KKEYN- 524
Query: 479 LDPGDSVGPRAGLDELDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLY 538
LD+ +FD+DY +F + DL L F + I+++ + L
Sbjct: 525 -----------FLDQRKMDFDQDYEEFCKQTNDLHNELRKFMDVTF---AKIQNTNQALR 570
Query: 539 MCGGLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVA 598
M + + +Y ++LE + A++D LY Q P + +N PP+A
Sbjct: 571 MLKKFERLNIPNLGIDDKYQLILENYGADIDMISKLYTKQKYD------PPLARNQPPIA 624
Query: 599 GQLKWSLELQERLEVSMKHLKHVEHP-VMSGAEAKLTYQKYDEMMELLRCHREKIYQQWV 657
G++ W+ +L R++ M+ + +HP V+S AEAK + Y+ M ++L ++ W+
Sbjct: 625 GKILWARQLFHRIQQPMQLFQ--QHPAVLSTAEAKPIIRSYNRMAKVLLEFEVLFHRAWL 682
Query: 658 AGVDQDCHFNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFS 717
+ ++ H L L+++ + + VNF ++ + RE + + Q E+ A SLF
Sbjct: 683 RQI-EEIHVGLEASLLVKAPGTGELFVNFDPQILILFRETECM-AQMGLEVSPLATSLFQ 740
Query: 718 ENETFRKFVGNLELIVGWYNEVMK----AVEFLLIKSELEAIDVKLLSAETTLFWNGEGV 773
+ + +++ N+++++ Y V A+E L++ L +D L L W +
Sbjct: 741 KRDRYKRNFSNMKMMLAEYQRVKSKIPAAIEQLIV-PHLAKVDEALQPGLAALTWTSLNI 799
Query: 774 FQYIQEVREILHNLQNRMQKAKQNIE-GISQAMKDWSANPL 813
Y++ + +L+ + + IE I +++ S+ PL
Sbjct: 800 EAYLENTFAKIKDLELLLDRVNDLIEFRIDAILEEMSSTPL 840
>gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens]
Length = 4116
Score = 1938 bits (5020), Expect = 0.0
Identities = 1174/3373 (34%), Positives = 1811/3373 (53%), Gaps = 155/3373 (4%)
Query: 1209 LRRKCQQFELK---QHEFRERFR-REAPFSFSDPNPYKSLNKQQKSISAMEGIMEALSKS 1264
L ++C +FEL+ H E FR RE + + + LN+ K+++ E ++K
Sbjct: 786 LIKRCSEFELRLEGYHRELESFRKREVMTTEEMKHNVEKLNELSKNLNRAFAEFELINKE 845
Query: 1265 GGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKK 1324
L E Y L+A + ++LW + E+W +N EQ+ +
Sbjct: 846 EELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFLLNAEQIAEEIGN 905
Query: 1325 FAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRA----VSELQNPAIRERHWQQLMQATQ 1380
+ L K + A L VK I + +S NP +++RHWQQ+ +
Sbjct: 906 MWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISCNPGMKDRHWQQISEIVG 965
Query: 1381 VKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPH 1440
+ K +E T L+++L+ + +++ I A KE +EK L + W + F +
Sbjct: 966 YEIKPTETTCLSNMLEFGFGKFVEKLEPIGAAASKEYSLEKNLDRMKLDWVNVTFSFVKY 1025
Query: 1441 PRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFE 1500
T T +L + + + L+D+ ++ Q + S ++ E W++KL + W +
Sbjct: 1026 RDTDTNILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLIRIQDNLDAWLK 1085
Query: 1501 VQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYN 1560
Q TW +LE IF SEDI Q+P + ++F ++ +K+LM AVK ++ A +P +
Sbjct: 1086 CQATWLYLEPIF-SSEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRILVAADQPRMAE 1144
Query: 1561 KLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFD 1620
KL+ L +K L +YLE KRL FPRF+F+S+ +LL+ILS DP+ V HL K F+
Sbjct: 1145 KLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRVQPHLKKCFE 1204
Query: 1621 SLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQE---CDLSGQVEVWLNRVLDRMCSTL 1677
+ KL+F + L++ +GM S E E + F Q+ + G VE WL +V M +++
Sbjct: 1205 GIAKLEFTDN-----LEI-VGMISSEKETVPFIQKIYPANAKGMVEKWLQQVEQMMLASM 1258
Query: 1678 RHEIPEAVVTYEEKPREQWILDYPAQVALTCTQIWWTTEVGLAFARLEEGYENAIRDYNK 1737
R I + Y + PR W+L +P QV + + I+WT EV A A EN + D+ K
Sbjct: 1259 REVIGLGIEAYVKVPRNHWVLQWPGQVVICVSSIFWTQEVSQALA------ENTLLDFLK 1312
Query: 1738 KQISQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIVAKVESSQAFTWQAQLR 1797
K Q+ ++ L+ G L++G R+ + + IDVHARDVVAK+ +V F W +QLR
Sbjct: 1313 KSNDQIAQIVQLVRGKLSSGARLTLGALTVIDVHARDVVAKLSEDRVSDLNDFQWISQLR 1372
Query: 1798 HRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGP 1857
+ W + I + Y YEYLGN+PRLVITPLTDRCY TL +L L +GGAP GP
Sbjct: 1373 YYW--VAKDVQVQIITTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALKLNLGGAPEGP 1430
Query: 1858 AGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEV 1917
AGTGKTETTKDL +AL VFNCS+ +DYK+ G +KGLAQ GAW CFDEFNRI VEV
Sbjct: 1431 AGTGKTETTKDLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIEVEV 1490
Query: 1918 LSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFR 1977
LSV+A Q+ +Q AI K K F F G + L PT +FITMNPGYAGRAELP+NLKALFR
Sbjct: 1491 LSVVAQQILSIQQAIIRKLKTFIFEGTELSLNPTCAVFITMNPGYAGRAELPDNLKALFR 1550
Query: 1978 PCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVL 2037
AM+VPD+ LI EI L + GFL++R LA+K + Y LC E LS Q HYD+G+RA+KSVL
Sbjct: 1551 TVAMMVPDYALIGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHYDYGMRAVKSVL 1610
Query: 2038 VVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNF 2097
AG+LK P E +L+RAL D N+ K + D+P+F G+I DLFP + +P+ F
Sbjct: 1611 TAAGNLKLKYPEENESVLLLRALLDVNLAKFLAQDVPLFQGIISDLFPGVVLPKPDYEVF 1670
Query: 2098 EKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNL 2157
K++ +I ++KLQ F+ K++Q+ E++ VRH IVG+ GK+ K L +L
Sbjct: 1671 LKVLNDNIKKMKLQPVPWFIGKIIQIYEMMLVRHGYMIVGDPMGGKTSAYKVLAAALGDL 1730
Query: 2158 ----KRKPVAVD---LDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWI 2210
+ + AV+ ++PKA+T +L+G + V+ EW DG+ + R+ A+ D KWI
Sbjct: 1731 HAANQMEEFAVEYKIINPKAITMGQLYGCFDQVSHEWMDGVLANAFREQASSLSDDRKWI 1790
Query: 2211 ILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGI 2270
I DG +D +WIE++NTV+DDNK L L S E I +N M L+FE + L A+PATVSR G+
Sbjct: 1791 IFDGPVDAIWIENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPADLEQASPATVSRCGM 1850
Query: 2271 LYINPADLGWNPVVSSWIERRKVQSEKANLMILFDKYL---PTCLDKLRFGFKKITPVPE 2327
+Y+ P LGW P+ S+++ K + ++ D ++ CL+ R K +
Sbjct: 1851 IYMEPHQLGWKPLKDSYMDTLPSSLTKEHKELVNDMFMWLVQPCLEFGRLHCKFVVQTSP 1910
Query: 2328 ITVIQTILYLLECLLTEKTVPPDSPRELYE------------LYFVFTCFWAFGGAMFQD 2375
I + +++ L LL E + EL E F+F+ W G + D
Sbjct: 1911 IHLAFSMMRLYSSLLDEIRAVEEEEMELGEGLSSQQIFLWLQGLFLFSLVWTVAGTINAD 1970
Query: 2376 QLVDYRVEFSKWWIN------EFKTIK------FPSQGTIFD-YYIDPDTKKFLPWTDKV 2422
+ V F + K++K FP +G+I+D Y+I + + WT +
Sbjct: 1971 SRKKFDVFFRNLIMGMDDNHPRPKSVKLTKNNIFPERGSIYDFYFIKQASGHWETWTQYI 2030
Query: 2423 PSFE--LDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLES 2480
E + + ++ T ET R +F+ ++ P++ VG GTGKS + + L
Sbjct: 2031 TKEEEKVPAGAKVSELIIPTMETARQSFFLKTYLDHEIPMLFVGPTGTGKSAITNNFLLH 2090
Query: 2481 LNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDK 2540
L + YL + F+ T++ Q ++ L+++ +GPP KK V F+DD+NMP +
Sbjct: 2091 LPKNTYLPNCINFSARTSANQTQDIIMSKLDRRRKGLFGPPIGKKAVVFVDDLNMPAKEV 2150
Query: 2541 YGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGSFT-IDSRLQRHFCVF 2599
YG P L+RQ +DH +W+D+ T DI + V M P G I R RH +
Sbjct: 2151 YGAQPPIELLRQWIDHGYWFDKKDTTRLDIVDMLLVTAMGPPGGGRNDITGRFTRHLNII 2210
Query: 2600 AVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKF 2659
+++ + LT I+++I+ H + + R LV A +++ FLPT K
Sbjct: 2211 SINAFEDDILTKIFSSIVDWHFG-KGFDVMFLRYGKMLVQATKTIYRDAVENFLPTPSKS 2269
Query: 2660 HYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTM 2719
HYVFNLRD S + QG+L L+ +RLW+HE RV+ D+++D++D++ +
Sbjct: 2270 HYVFNLRDFSRVIQGVLLCPHTHLQDVEKCIRLWIHEVYRVFYDRLIDKEDRQVFFNMVK 2329
Query: 2720 ASTKKFFDDLGDELLF------------AKPNIFCHFAQGIGDPK-YVPVTDMAPLNKLL 2766
+T F +++L + F + + D K Y +TD+ L ++
Sbjct: 2330 ETTSNCFKQTIEKVLIHLSPTGKIVDDNIRSLFFGDYFKPESDQKIYDEITDLKQLTVVM 2389
Query: 2767 VDVLDSYNEVN-AVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAY 2825
L+ +N ++ A M+LV+F A+ HI RI R+L+ +G+ LLVG+GGSG+QS ++L+ +
Sbjct: 2390 EHYLEEFNNISKAPMSLVMFRFAIEHISRICRVLKQDKGHLLLVGIGGSGRQSAAKLSTF 2449
Query: 2826 ISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLL 2885
++ +++QI + K Y D + DL ++ V +VFL D+Q+ +E F+ IN LL
Sbjct: 2450 MNAYELYQIEITKNYAGNDWREDLKKIILQVGVATKSTVFLFADNQIKDESFVEDINMLL 2509
Query: 2886 ASGEIPGLFMEDEVENIISSMRPQVKSLG--MNDTRETCWKFFIEKVRRQLKVILCFSPV 2943
+G++P +F DE +I+ M+ ++ G + T + + FFIE+V ++ L SP+
Sbjct: 2510 NTGDVPNIFPADEKADIVEKMQTAARTQGEKVEVTPLSMYNFFIERVINKISFSLAMSPI 2569
Query: 2944 GSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPVIKASISFFMSYVH 3003
G R R R FP+++NC IDWF WP DAL V+ +FLE+ E I+ + Y
Sbjct: 2570 GDAFRNRLRMFPSLINCCTIDWFQSWPTDALELVANKFLEDVELDDNIRVEVVSMCKYFQ 2629
Query: 3004 TTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQST 3063
+V ++S Y RR+NY TP ++LE I ++ LL KR E+ R GL KL
Sbjct: 2630 ESVKKLSLDYYNKLRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRYLTGLQKLDFA 2689
Query: 3064 ASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNV 3123
ASQV ++ +L + +L +E +++ + E + +K + +E + V
Sbjct: 2690 ASQVAVMQRELTALQPQLILTSEETAKMMVKIEAETREADGKKLLVQADEKEANVAAAIA 2749
Query: 3124 TEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMIL---- 3179
+ CE DLA+A PAL AA ALDTLN +++ +KS +PP V V ++ I+
Sbjct: 2750 QGIKNECEGDLAEAMPALEAALAALDTLNPADISLVKSMQNPPGPVKLVMESICIMKGMK 2809
Query: 3180 ------TAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKP-YQGNP 3232
+ GK+ +D W +K ++G + FL+SLK +DK++IP +K + + +P
Sbjct: 2810 PERKPDPSGSGKMIED-YWGVSKKILGDL-KFLESLKTYDKDNIPPLTMKRIRERFINHP 2867
Query: 3233 TFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCD----VAPKRQALEEANAELAEAQEKLS 3288
F P I++ S+A GLC W VR EVY VAPKR+ L EA +LA +KL+
Sbjct: 2868 EFQPAVIKNVSSACEGLCKW----VRAMEVYDRVAKVVAPKRERLREAEGKLAAQMQKLN 2923
Query: 3289 RIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAE 3348
+ + ++ + L L FE+ +K ++ + ++ ++ A +L+ GL E RW E
Sbjct: 2924 QKRAELKLVVDRLQALNDDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGGEKDRWTE 2983
Query: 3349 SVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLD 3408
+ + L GDVLL S V+Y+G FT YR + + W+ + +P G
Sbjct: 2984 AARQLGIRYTNLTGDVLLSSGTVAYLGAFTVDYRVQCQNQ-WLAECKDKVIP-----GFS 3037
Query: 3409 PLSL---LTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYR 3465
SL L D + W GLP D S +N I+ N+ RW L++D Q KWIKN +
Sbjct: 3038 DFSLSHTLGDPIKIRAWQIAGLPVDSFSIDNGIIVSNSRRWALMIDPHGQANKWIKNMEK 3097
Query: 3466 -SELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKG--KYIKI 3522
++L I+ +Y+ ++E A+ G +LIENIGE +D ++P+L + T K+ +Y+++
Sbjct: 3098 ANKLAVIKFSDSNYMRMLENALQLGTPVLIENIGEELDASIEPILLKATFKQQGVEYMRL 3157
Query: 3523 GDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDL 3582
G+ +EY F+L + T+ NPHY PE+ + L+NF++T GL+DQLL V AKE+P+L
Sbjct: 3158 GENIIEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMITPLGLQDQLLGIVAAKEKPEL 3217
Query: 3583 EQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKV 3642
E+ K L + K LKE+ED +L LS + GN L D ++ L ++K + EI EK
Sbjct: 3218 EEKKNQLIVESAKNKKHLKEIEDKILEVLSMSKGNILEDETAIKVLSSSKVLSEEISEKQ 3277
Query: 3643 VEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTT 3702
A +TE +I+E R Y+P A ++ ++F ++DL I P+YQ+SL F ++ ++ +T
Sbjct: 3278 KVASMTETQIDETRMGYKPVAVHSATIFFCISDLANIEPMYQYSLTWFINLYMHSLTHST 3337
Query: 3703 PANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLL 3762
+ E+ R+ + D T S+Y R LFE+DKL+F +T ++ KKE+ FLL
Sbjct: 3338 KSEELNLRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKQKKEITEEVWYFLL 3397
Query: 3763 RFPFKAGVVSP---VDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEK 3819
P +L + W I S + + L +E + WK + +S P +
Sbjct: 3398 TGGIALDNPYPNPAPQWLSEKAWAEIVRASALPKLHGLMEHLEQNLGEWKLIYDSAWPHE 3457
Query: 3820 EIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSP 3879
E P WK L+K+ ++RCLRPD+M A++ F+ E MG ++E + + SY +SS
Sbjct: 3458 EQLPGSWKFSQGLEKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAPTFDLQGSYNDSSC 3517
Query: 3880 STSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHW 3939
+ F+LSP DP+ + LG + + +SLGQGQ +A ++ A + G W
Sbjct: 3518 CAPLIFVLSPSADPMAGLLKFADDLG--MGGTRTQTISLGQGQGPIAAKMINNAIKDGTW 3575
Query: 3940 VILQNIHLVARWLGTLDKKLER--YSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIK 3997
V+LQN HL A W+ TL+K E ++ +R+++++ P+ P IL+N IK
Sbjct: 3576 VVLQNCHLAASWMPTLEKICEEVIVPESTNARFRLWLTSYPSEK-----FPVSILQNGIK 3630
Query: 3998 ITNEPPTGMHANLHKALDLFTQDTL------EMCTKEMEFKCMLFALCYFHAVVAERRKF 4051
+TNEPP G+ ANL L + D + + C K + ++ MLF LC+FHAVV ERR F
Sbjct: 3631 MTNEPPKGLRANL---LRSYLNDPISDPVFFQSCAKAVMWQKMLFGLCFFHAVVQERRNF 3687
Query: 4052 GAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLC 4111
G GWN Y FN DL IS+ + +L +VP+D L YL GE YGG +TDD DRRL
Sbjct: 3688 GPLGWNIPYEFNESDLRISMWQIQMFLNDYKEVPFDALTYLTGECNYGGRVTDDKDRRLL 3747
Query: 4112 RTYLAEYIRTEMLEGDVLLAPG--FQIPPNLDYKGYHEYIDENLP-PESPYLYGLHPNAE 4168
+ L+ + E+ E LAPG + IPP+ Y+ Y +Y+ NLP P ++GLH NA+
Sbjct: 3748 LSLLSMFYCKEIEEDYYSLAPGDTYYIPPHGSYQSYIDYL-RNLPITAHPEVFGLHENAD 3806
Query: 4169 IGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKVKAVLDDILEKIPETFNMAEIMA- 4227
I + +LF VL P+++ G+G S +E V+ + DIL K+P F++ E+M
Sbjct: 3807 ITKDNQETNQLFEGVLLTLPRQS---GGSGKSPQEVVEELAQDILSKLPRDFDLEEVMKL 3863
Query: 4228 -KAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTV 4286
+ V QE R N LT +RRSL L +KG++ +++++E++ ++ V
Sbjct: 3864 YPVVYEESMNTVLRQELIRFNRLTKVVRRSLINLGRAIKGQVLMSSELEEVFNSMLVGKV 3923
Query: 4287 PDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQS 4346
P W A++YPS+ L + ADLL R+ + W D P W++GF+ QSFLT + Q+
Sbjct: 3924 PAMWAAKSYPSLKPLGGYVADLLARLTFFQEW-IDKGPPVVFWISGFYFTQSFLTGVSQN 3982
Query: 4347 MARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKE 4406
ARK P+D + EVT + M P +G+Y+ GLF+EGARWD +T I E+ K
Sbjct: 3983 YARKYTIPIDHIGFEFEVTPQETV-MENNPEDGAYIKGLFLEGARWDRKTMQIGESLPKI 4041
Query: 4407 LTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPT---------YVWTFNLKTKEKAA 4457
L +P+I++K ++IY CPVYKT R T YV + L T
Sbjct: 4042 LYDPLPIIWLKPGESAMFLHQDIYVCPVYKTSARRGTLSTTGHSTNYVLSIELPTDMPQK 4101
Query: 4458 KWILAAVALLLQV 4470
WI VA L Q+
Sbjct: 4102 HWINRGVASLCQL 4114
>gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens]
Length = 4490
Score = 1926 bits (4989), Expect = 0.0
Identities = 1180/3583 (32%), Positives = 1910/3583 (53%), Gaps = 126/3583 (3%)
Query: 955 AKDRMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNF 1014
A+ N+ + ++ D+ ++ +SS V + K A E F++Y LWT++ +K F
Sbjct: 966 ARKLKNFYPGVAEHKDISKLVLLLSSSVNSLRKAAHEALQDFQKYKTLWTEDRDVKVKEF 1025
Query: 1015 LIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCD 1074
L P+L + + +I Y +E+ + + V G L+
Sbjct: 1026 LANN--------------------PSLTEIRSEILHYATFEQEIDELKPIIVV-GALELH 1064
Query: 1075 CRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEV 1134
P K AL + W + R+L+ ++ + AF+ L++P++ D D +
Sbjct: 1065 TEPMKLALSIEAKAWKMLLCRYLNEEYKKKMSYMIAFINEYLKKLSRPIR--DLDDVRFA 1122
Query: 1135 MGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQV 1194
M L +++ + D P+++ +L + E+ +E + L + + A+ V
Sbjct: 1123 MEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVEVTKEESEAVDTLRYSFNKLQSKAVSV 1182
Query: 1195 KLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKQQKSISAM 1254
+ + +Q S L + F F E + E P + P P ++ N+ Q ++
Sbjct: 1183 QEDLVQVQPKFKSNLLESVEVFREDVINFAEAYELEGPMVPNIP-PQEASNRLQIFQASF 1241
Query: 1255 EGIMEAL---SKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWK 1311
+ + S LF +PV DY+ L +E+ LL++L+ + V +SI + W
Sbjct: 1242 DDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSSISGYYEILWG 1301
Query: 1312 DINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERH 1371
D+++E+++ + +F R L K +K W AF+ L + + S + + N A+++RH
Sbjct: 1302 DVDIEKINAELLEFQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEMMTNKAMKQRH 1361
Query: 1372 WQQLMQATQVKFKM-SEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTW 1430
W ++ + T F + S+ L ++++ L ++D++ +I A+KE +E L + W
Sbjct: 1362 WDRISELTGTPFDVESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIEAKLTQVIENW 1421
Query: 1431 SMMEFQHEPHPRTGTMMLKSSEV--LVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKL 1488
+ G ++LK +E ++ +ED+ + L +L+ ++Y A F K + +W KL
Sbjct: 1422 TNQNLSFAAFKGKGELLLKGTESGEIITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKL 1481
Query: 1489 STADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPN 1548
ST+ +I W VQ W +LE++F+G DI QLP +++RF +I++ + +M+ A + PN
Sbjct: 1482 STSSDIIEEWLVVQNLWVYLEAVFVGG-DIAKQLPQEAKRFQNIDKSWIKIMQRAHENPN 1540
Query: 1549 VVEA-TSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGND 1607
V+ + L L + L +C+K+L YLE KRL FPRF+FVS LL+IL +D
Sbjct: 1541 VINCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASD 1600
Query: 1608 PVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLN 1667
+ HL + D++ ++ F D+ + V S+E E +V D G VE+WL
Sbjct: 1601 SHTIQPHLPAVSDNINEVTFHAKDYDRIMAV----ISREGEKIVLDNSVMAKGPVEIWLL 1656
Query: 1668 RVLDRMCSTLRHEIPEAVVTYEEKPRE--QWILDYPAQVALTCTQIWWTTEVGLAFARLE 1725
+L S+L + I A + + ++ +PAQV L Q+ WT + A +
Sbjct: 1657 DLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQVGLLGIQMLWTHDSEEALRNAK 1716
Query: 1726 EGYENAIRDYNKKQISQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIVAKVE 1785
+ ++ N+K + LN LI+ +L+ DR+K T+ TI VH RD+ ++ ++
Sbjct: 1717 DD-RKIMQVTNQKFLDILNTLISQTTHDLSKFDRVKFETLITIHVHQRDIFDDLVKMHIK 1775
Query: 1786 SSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQS 1845
S F W Q R + E+ +I D Y E+LG T RLVITPLTDRCYITL Q+
Sbjct: 1776 SPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQNEFLGCTDRLVITPLTDRCYITLAQA 1835
Query: 1846 LHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWG 1905
L + MGGAPAGPAGTGKTETTKD+GR LG V VFNCS+QMD++ G I+KGLAQ+G+WG
Sbjct: 1836 LGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWG 1895
Query: 1906 CFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFL-GEIIGLIPTVGIFITMNPGYAG 1964
CFDEFNRI + VLSV A Q+ V A + +KK F F G+ + L P GIF+TMNPGYAG
Sbjct: 1896 CFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSDGDCVDLNPEFGIFLTMNPGYAG 1955
Query: 1965 RAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQD 2024
R ELPENLK FR AM+VPD ++I + L + GFLE +LA+KF LY LC+E L+KQ
Sbjct: 1956 RQELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQV 2015
Query: 2025 HYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLF 2084
HYD+GLR I SVL GS KR P +E ++MR LRD N+ K+V +D P+F+ LI DLF
Sbjct: 2016 HYDFGLRNILSVLRTLGSQKRARPEDSELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLF 2075
Query: 2085 PALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKS 2144
P L + + + + L + LK+VQL E VRH + +G +GSGK+
Sbjct: 2076 PGLQLDSNTYAELQNAVAHQVQIEGLINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKT 2135
Query: 2145 QVLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITH 2204
V+ L K R + ++PKA+T ++FG ++ T +W DG+FST+ R
Sbjct: 2136 TVITILMKAQTECGRPHREMRMNPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKK 2195
Query: 2205 DGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPAT 2264
++ILDG +D +WIE+LN+V+DDNK LTLA+ +RIP+ + +L+FE+ ++ A+PAT
Sbjct: 2196 GENIFLILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPAT 2255
Query: 2265 VSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITP 2324
VSR G++YI+ + L W P++ +W+++R Q E A + L++K ++
Sbjct: 2256 VSRMGMVYISSSALSWRPILQAWLKKRTAQ-EAAVFLTLYEKVFEDTYTYMKLNLNPKMQ 2314
Query: 2325 VPEITVIQTILYLLECLLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEF 2384
+ E I L LLE L+ K S E FVF W+ GA+ + + + F
Sbjct: 2315 LLECNYIVQSLNLLEGLIPSKEEGGVSCVEHLHKLFVFGLMWSL-GALLELESREKLEAF 2373
Query: 2385 SKWWINEFKTIKFP--SQGTIFDYYIDPDTKKFLPWTDKVPSFELDPD-VPLQAS-LVHT 2440
+ ++ + P S T++++Y+ D + W K+ + D +P +S LV
Sbjct: 2374 LRQHESKLDLPEIPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPN 2432
Query: 2441 TETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSA 2500
+ IR + +D + ++ V+L G GT K+V++ L+ + + L +++ F+ T
Sbjct: 2433 VDNIRTNFLIDTIAKQHKAVLLTGEQGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEPM 2492
Query: 2501 MLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWY 2560
M Q +E ++K+ G YGPPG +K+ FIDD+NMP ++++G + ++RQ M+ Y
Sbjct: 2493 MFQRTIESYVDKRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMY 2552
Query: 2561 DRHK----LTLKDIHNCQYVACM-NPTSGSFTIDSRLQRHFCVFAVSFPGQEALTTIYNT 2615
K T+ D+ Q +A M +P G I RL+R F VF + P ++ I+
Sbjct: 2553 SLDKPGDFTTIVDV---QLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGI 2609
Query: 2616 ILTQHL-AFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQG 2674
I + RS I + LV+ L Q LPT KFHY+FNLRDLS I+QG
Sbjct: 2610 IGCGYFDPCRSFKPQICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQG 2669
Query: 2675 LLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLH-RVTMASTKKFFDDLGDEL 2733
+L AE + L+ L+ HE RV D+ + +D++ + +T A + D +
Sbjct: 2670 MLTIKAEECASIPTLLSLFKHECSRVIADRFITPEDEQWFNAHLTRAVEENIGSDAASCI 2729
Query: 2734 LFAKPNIFCHFAQGIGDP----------KYVPVTDMAPLNKLLVDVLDSY----NEV--N 2777
L F F + + +P + + ++ P L + L Y NE+
Sbjct: 2730 L--PEPYFVDFLREMPEPTGDEPEDSVFEVPKIYELMPSFDFLAEKLQFYQRQFNEIIRG 2787
Query: 2778 AVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLK 2837
++LV F+DA+ H+ +I+RI+ + GNALLVGVGGSGKQSLSRLA++I+G +FQITL
Sbjct: 2788 TSLDLVFFKDAMTHLIKISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITLT 2847
Query: 2838 KGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMED 2897
+ Y + +L DL A Y A F+ TDS++ +E FL +N+LL+SGEI LF D
Sbjct: 2848 RSYNVTNLTDDLKALYKVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSGEISNLFARD 2907
Query: 2898 EVENI----ISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARK 2953
E++ I IS M+ ++ T + +++FI + R+ L V+LCFSPVG R R+ K
Sbjct: 2908 EMDEITQGLISVMKRELPR--HPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARSLK 2965
Query: 2954 FPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGI--PVIKASISFFMSYVHTTVNEMSR 3011
FP +++ +DWF WP +AL++V++ FL + + IK + M H V+E
Sbjct: 2966 FPGLISGCTMDWFSRWPREALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMVSESCE 3025
Query: 3012 VYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLK 3071
Y RR + TPK++L I Y+N+ A+K + + ER+ GL KL + V L
Sbjct: 3026 SYFQRYRRRAHVTPKSYLSFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASESVAKLS 3085
Query: 3072 AKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACE 3131
LA++E EL + AD+++ V + A+ +K K + + K + I + ++ E
Sbjct: 3086 QDLAVKEKELAVASIKADEVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSEKVKAE 3145
Query: 3132 TDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMIL--------TAPG 3183
+ L A+PAL A+ AL+T+ N++ ++ PP ++ + V++L T
Sbjct: 3146 SKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDPVTMDP 3205
Query: 3184 GKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKS 3243
K SW + +M FL SL++F K+ I E ++ +PY + E +
Sbjct: 3206 EKSCCKPSWGESLKLMSATG-FLWSLQQFPKDTINEETVELLQPYFNMDDYTFESAKKVC 3264
Query: 3244 TAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSN 3303
AGL SW + + FY + +V P + L + LA A +L + + + E A L
Sbjct: 3265 GNVAGLLSWTLAMAIFYGINREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQAELDK 3324
Query: 3304 LTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGD 3363
+ + F+ A EK+ +AD + + A+ L+ GL+ E IRW + + F++Q L GD
Sbjct: 3325 VQAKFDAAMNEKMDLLNDADTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINRLVGD 3384
Query: 3364 VLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWN 3423
+LL + F+SY+G F + +RN L++ W + K IP T L+ +S+L D + W
Sbjct: 3385 ILLCTGFLSYLGPFNQIFRNYLLKDQWEMELRARK--IPFTENLNLISMLVDPPTIGEWG 3442
Query: 3424 NQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYR-SELKAIRLGQKSYLDVI 3482
QGLP D +S +N I+ R+PL++D Q QG WIK+K + ++L+ L K + +
Sbjct: 3443 LQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKENDLQVTSLNHKYFRTHL 3502
Query: 3483 EQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGK--YIKIGDKEVEYHPKFRLILHTK 3540
E ++S G LLIE+I E +DP LD +L +N IK G +K+GDKE + F+L + TK
Sbjct: 3503 EDSLSLGRPLLIEDIHEELDPALDNVLEKNFIKSGTTFKVKVGDKECDIMDTFKLYITTK 3562
Query: 3541 YFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVL 3600
NP + PE+ A+ ++I+F VT GLE+QLL V+ E+ +LE + L + K +
Sbjct: 3563 LPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELEAERVKLLEDVTFNKRKM 3622
Query: 3601 KELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYR 3660
KELED+LL +LSA G+ + D +L+ L TTK TA+E+ EK+ A TE+KIN A+E +R
Sbjct: 3623 KELEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAEVSEKLHVAAETEIKINAAQEEFR 3682
Query: 3661 PAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITY 3720
PAA R S+LYF++ +++ +N +YQ SL F +F++++ R+ + ++R+ N+ + +TY
Sbjct: 3683 PAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKRITNIIEYLTY 3742
Query: 3721 SVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLR----FPFKAGVVSPVDF 3776
V+ Y+ RGL+E K +F+ +T ++ + + E L++ KA P +
Sbjct: 3743 EVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREFQALIKGGAALDLKACPPKPYRW 3802
Query: 3777 LQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNK-TALQKL 3835
+ W + LS++ +F + + I + K WK + +APE+EI P + + KL
Sbjct: 3803 ILDMTWLNLVELSKLPQFAEIMNQISRNEKGWKSWFDKDAPEEEIIPDGYNDSLDTCHKL 3862
Query: 3836 CMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLK 3895
++R PDR + + ++ + + K+ E + K++EES T + LS G DP
Sbjct: 3863 LLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTWEESDTRTPLICFLSMGSDPTN 3922
Query: 3896 DVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQNIHLVARWLGTL 3955
++AL KKL + +S+GQGQEV A + ++ ++G WV+LQN HL ++ L
Sbjct: 3923 QIDALAKKLKL-----ECRTISMGQGQEVHARKLIQMSMQQGGWVLLQNCHLGLEFMEEL 3977
Query: 3956 DKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALD 4015
+ L + S + +RV+I+ EP P +L+ ++K TNEPP G+ A L +
Sbjct: 3978 LETLIT-TEASDDSFRVWITTEPHDR-----FPITLLQTSLKFTNEPPQGVRAGLKRTFA 4031
Query: 4016 LFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLY 4075
QD L++ M +K ML+ + + H+ V ERRKFG GWN Y FN+ D + S+ +
Sbjct: 4032 GINQDLLDISNLPM-WKPMLYTVAFLHSTVQERRKFGPLGWNIPYEFNSADFSASVQFIQ 4090
Query: 4076 NYL---EANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAP 4132
N+L + V W+ +RY+ GE+ YGG +TDD+D+RL + + +M E
Sbjct: 4091 NHLDECDIKKGVSWNTVRYMIGEVQYGGRVTDDFDKRLLNCFARVWFSEKMFEPSFCFYT 4150
Query: 4133 GFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETD 4192
G++IP Y EYI ++P ++GLHPNA+I + + T+ + T+ +QPKE
Sbjct: 4151 GYKIPLCKTLDQYFEYIQSLPSLDNPEVFGLHPNADITYQSNTASAVLETITNIQPKE-- 4208
Query: 4193 SGAGTGVSREEKVKAVLDDILEKIPETFNMAEI---MAKAAEKTPYVVVAFQECERMNIL 4249
SG G G +RE V + +D+L K+P + E+ + K + QE +RM +
Sbjct: 4209 SGGGVGETREAIVYRLSEDMLSKLPPDYIPHEVKSRLIKMGHLNSMNIFLRQEIDRMQRV 4268
Query: 4250 TNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLL 4309
+ +R SL +L L ++G + ++ ++ D ++ +P W ++ S L W+ +LL
Sbjct: 4269 ISILRSSLSDLKLAIEGTIIMSENLRDALDNMYDARIPQLWKRVSWDSST-LGFWFTELL 4327
Query: 4310 LRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNE-WPLDKMCLSVEVTKKN 4368
R + W + P W+ GFFNPQ FLTA+ Q + R ++ W LD + + EV ++
Sbjct: 4328 ERNAQFSTWIFE-GRPNVFWMTGFFNPQGFLTAMRQEVTRAHKGWALDTVTIHNEVLRQT 4386
Query: 4369 REDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKN 4428
+E++T+PP EG Y+YGL+M+GA WD + G + E+ K L +PV+ I AI +
Sbjct: 4387 KEEITSPPGEGVYIYGLYMDGAAWDRRNGKLMESTPKVLFTQLPVLHIFAINSTAPKDPK 4446
Query: 4429 IYECPVY-KTRIRGPTYVWTFNLKTKEKAAKWILAAVALLLQV 4470
+Y CP+Y K R T++ L+T WIL VALL +
Sbjct: 4447 LYVCPIYKKPRRTDLTFITVVYLRTVLSPDHWILRGVALLCDI 4489
Score = 151 bits (381), Expect = 2e-35
Identities = 153/743 (20%), Positives = 308/743 (41%), Gaps = 61/743 (8%)
Query: 69 PQSLKSKGVYFIKTKSE-NINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL------- 120
P LK ++F++ +++ IN + L+ + + L+ + ++L+++
Sbjct: 11 PDKLKGLCIFFVRCRNDVAINVKTIQEEALFTVLDASK--GLLNGIRDMLANIFLPAVLA 68
Query: 121 ------LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGT 174
LNQS+ + +E I + + L + G +K KT+ +
Sbjct: 69 TNNWGALNQSKQGESEKHIFTETINRYLSFLDGARISIEGTVKLKTIDNVNF------SK 122
Query: 175 LESMERIPSSLDNL-LLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDA 233
L + E + ++ N +H +E ++ W QI VL +S Q + P E E W
Sbjct: 123 LHTFEEVTAAASNSETVHQLEEVLMVWYKQIEQVLI-ESEQMRKEAGDSGPLTELEHWKR 181
Query: 234 RLLNLKCIHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLR 293
I EQ+ P ++ +L A S +++ +T+ E+ D V YL L
Sbjct: 182 MSAKFNYIIEQIKGPSCKAVINVLNVAHSKLLKNWRDLDARITDTANESKDNVRYLYTLE 241
Query: 294 ILLEEMEQADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFL 353
+ + + D + I +++ I I S YYNT R+ + + NQ++ + ++
Sbjct: 242 KVCQPLYNHDLVSMAHGIQNLINAIRMIHGVSRYYNTSERMTSLFIKVTNQMVTACKAYI 301
Query: 354 SPEEVLKGLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLA 413
+ + E VL I + + KE ++ KL + +E
Sbjct: 302 TDGGLNHVWDQETPVVLKKIQDCIFLFKEYQASFH---KTRKLISESSGEKSFEVSEMYI 358
Query: 414 FSRINSFFQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFAD 473
F + +F +R++ I E+ + L + G+ +++ IY V +
Sbjct: 359 FGKFEAFCKRLEKITEMITVVQTYSTLSNSTIEGI--DIMAIKFRNIYQGVKKK------ 410
Query: 474 CKYDPLDPGDSVGPRAGLDELDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSS 533
+YD LDP + FD D+ DF KI L+ ++ F + +
Sbjct: 411 -QYDILDP------------RRTEFDTDFLDFMTKINGLEVQIQAFMNSSFGKILSSQQA 457
Query: 534 AKLLYMCGGLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKN 593
+LL L P + E+ +L+ + AELD K LY +Q + P + +N
Sbjct: 458 LQLLQRFQKL-NIPCLGLEINHTIERILQYYVAELDATKKLYHSQK------DDPPLARN 510
Query: 594 MPPVAGQLKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIY 653
MPP+AG++ W +L R+ + + ++S + K ++Y+++ +L +
Sbjct: 511 MPPIAGKILWVRQLYRRISEPINYF-FKNSDILSSPDGKAVIRQYNKISYVLVEFEVVYH 569
Query: 654 QQWVAGVDQDCHFNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAE 713
W+ + Q H+ L L +R + + VNF ++ V+RE K + + + ++P+ A+
Sbjct: 570 TAWIREISQ-LHYALQATLFVRHPETGKLLVNFDPKILEVVRETKCM-IKMKLDVPEQAK 627
Query: 714 SLFSENETFRKFVGNLELIVGWYNEVMKAVEFL---LIKSELEAIDVKLLSAETTLFWNG 770
L + L+ ++ +Y+E+ + V + L+ +++ ++ L T L W+
Sbjct: 628 RLLKLESKLKADKLYLQGLLQYYDELCQEVPSVFVNLMTPKMKKVESVLRQGLTVLTWSS 687
Query: 771 EGVFQYIQEVREILHNLQNRMQK 793
+ + QEV +L ++K
Sbjct: 688 LTLESFFQEVELVLDMFNQLLKK 710
>gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]
Length = 4646
Score = 1368 bits (3540), Expect = 0.0
Identities = 949/3400 (27%), Positives = 1675/3400 (49%), Gaps = 281/3400 (8%)
Query: 1276 KQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKE 1335
++++ E++ LK +W + V I+ K W + ++ + ++S
Sbjct: 1317 ERVQVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPAR 1376
Query: 1336 MKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLADLL 1395
++ + ++ + +K + V EL++ A+++RHW+QLM+ V + +SE TL +
Sbjct: 1377 LRQYASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSE-LTLGQIW 1435
Query: 1396 QLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEVLV 1455
++L E V++++ A E +E+ LK + W+ E + + +++ + L
Sbjct: 1436 DVDLQKNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNY-QNKCRLIRGWDDLF 1494
Query: 1456 ETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGS 1515
++++ + + +S Y F ++ SW+ KL+ ++ +W +VQR W +LE IF GS
Sbjct: 1495 NKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGS 1554
Query: 1516 EDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKA 1575
DI+ LP ++QRF I+ EF ALM+ K+P V++ + G+ LE L L +KA
Sbjct: 1555 ADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKA 1614
Query: 1576 LAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKP 1635
L EYLE +R +FPRFYFV DLL+I+ N + ++ +H K+F + + D S
Sbjct: 1615 LGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNS--- 1671
Query: 1636 LKVGLGMYSKEDEYMVFDQECDLSGQVEV--WLNRVLDRMCSTLRHEIPEAVVTYEEKPR 1693
V LG+ S+E E ++F ++ ++ WL V M TL + E+V E +
Sbjct: 1672 --VVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGK 1729
Query: 1694 EQ---------WILDYPAQVALTCTQIWWTTEVGLAFARLEEGYENA-IRDYNKKQISQL 1743
WI Y AQ+ + QI W+ V A + + G + A + L
Sbjct: 1730 ATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTL 1789
Query: 1744 NVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIVAKVESSQAFTWQAQLRHRWDEE 1803
NVL ++ R K+ + T VH RDV +I +K++++++F W +Q+R +D +
Sbjct: 1790 NVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPK 1849
Query: 1804 KRHCFANI----CDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAG 1859
+ + +A+ Y +EYLG +LV TPLTDRCY+T+TQ+L +GG+P GPAG
Sbjct: 1850 QTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAG 1909
Query: 1860 TGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLS 1919
TGKTE+ K LG LG V VFNC E D+++ G I+ GL Q GAWGCFDEFNR+ +LS
Sbjct: 1910 TGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLS 1969
Query: 1920 VIAVQVKCVQDAIRAKKK----------AFNFLGEIIGLIPTVGIFITMNPGYAGRAELP 1969
++ QV+C+Q+A+R L + + + P + IFITMNPGYAGR+ LP
Sbjct: 1970 AVSQQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLP 2029
Query: 1970 ENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWG 2029
+NLK LFR AM PD +LI ++ML ++GF A +LA K + + LC E LS Q HYD+G
Sbjct: 2030 DNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFG 2089
Query: 2030 LRAIKSVLVVAGSLKRGDPSRA---------------------EDQVLMRALRDFNIPKI 2068
LRA+KSVLV AG++KR + E ++L++++ + +PK+
Sbjct: 2090 LRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKL 2149
Query: 2069 VTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDS------FVLKVVQ 2122
V +D+P+ L+ D+FP + R + +K+ E+ L D +V KV+Q
Sbjct: 2150 VAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQ 2209
Query: 2123 LEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKR-KPVAVDLDPKAVTCDELFGIIN 2181
L ++ Q+ H + +VG +GSGKS + L K + L+ + VA +DPKA++ D L+G ++
Sbjct: 2210 LYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLD 2269
Query: 2182 PVTREWKDGLFSTIMRDLANITH---DGPKWIILDGDIDPMWIESLNTVMDDNKVLTLAS 2238
P TREW DGLF+ ++R + + +WI+ DGD+DP W+E+LN+V+DDNK+LTL +
Sbjct: 2270 PNTREWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPN 2329
Query: 2239 NERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRK------ 2292
ER+ L +R++FE+ L+ AT ATVSR G+++ + L + + ++++ R +
Sbjct: 2330 GERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDE 2389
Query: 2293 -------------------------VQSEKANLMILF--DKYLPTCLDKLRFGFKKITPV 2325
+Q + A +M + L T + F + I +
Sbjct: 2390 GEDEAQRRRKGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDL 2449
Query: 2326 PEITVIQTILYLLE--C--LLTEKTVPPDSPRELYEL------YFVFTCFWAFGGAMFQD 2375
+ + ++ +L C + PD P ++ +L Y V+ W+ G D
Sbjct: 2450 TRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSG----D 2505
Query: 2376 QLVDYRVEFSKWWINEFKTIKFPSQGTI--FDYYIDPDTKKFLPWTDKVPSFELD----- 2428
+ R E ++ I T+ P+ I DY + + ++ PW KVP E++
Sbjct: 2506 SRLKMRAELGEY-IRRITTVPLPTAPNIPIIDYEVSI-SGEWSPWQAKVPQIEVETHKVA 2563
Query: 2429 -PDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNTDNYL 2487
PDV +V T +T+R + + + P++L G G+GK++ + L +L
Sbjct: 2564 APDV-----VVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPD---- 2614
Query: 2488 VQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGT--------KKLVYFIDDMNMPEVD 2539
++ V NF +SA +L K + P G K LV F D++N+P++D
Sbjct: 2615 MEVVGLNF--SSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMD 2672
Query: 2540 KYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTS--GSFTIDSRLQRHFC 2597
KYGT + IRQ ++H +Y T + Q+V NP + G + R RH
Sbjct: 2673 KYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVP 2732
Query: 2598 VFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAI 2657
V V +PG +LT IY T + A + +++ + L AA + + F
Sbjct: 2733 VVYVDYPGPASLTQIYGTF---NRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDT- 2788
Query: 2658 KFHYVFNLRDLSNIFQGLLFSTAEVLKTPLD-LVRLWLHETERVYGDKMVDEKDQETLHR 2716
+ HY+++ R+++ +G+ + + P++ L+R+W HE R++ D++V+++++
Sbjct: 2789 QPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDE 2848
Query: 2717 VTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNEV 2776
K F ++ E ++P ++ ++ Y+PV D L + L + E
Sbjct: 2849 NIDTVALKHFPNIDREKAMSRPILYSNWLS----KDYIPV-DQEELRDYVKARLKVFYEE 2903
Query: 2777 NAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITL 2836
+ LVLF + + H+ RI+RI P+G+ LL+GV G+GK +LSR A+++GL V+QI +
Sbjct: 2904 ELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKV 2963
Query: 2837 KKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFME 2896
+ Y D DL ++ KN F+M +S V + FL +N LLA+GE+PGLF
Sbjct: 2964 HRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEG 3023
Query: 2897 DEVENIISSMRPQVKSLG-MNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFP 2955
DE +++ + + G M D+ E +K+F +V R L V+ +P L+ RA P
Sbjct: 3024 DEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSP 3083
Query: 2956 AVVNCTAIDWFHEWPEDALVSVSARFLEETE----------GIPVI----------KASI 2995
A+ N ++WF +W +AL V F + + +PV+ + +I
Sbjct: 3084 ALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAI 3143
Query: 2996 SFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLEN 3055
+VH T+++ + R TP+ +L+ I Y NL +KR+EL + L
Sbjct: 3144 VNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNV 3203
Query: 3056 GLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVK 3115
GL K++ T QV++L+ L I+ EL+ KN +A+ ++ + + ++ K+K ++ + + +
Sbjct: 3204 GLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQ 3263
Query: 3116 VEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAA 3175
+ + + +KQ + + DL K EPA++ AQ A+ ++ K +L E++S +PP AV +
Sbjct: 3264 LHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALES 3323
Query: 3176 VMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKP-YQGNPTF 3234
+ +L G+ D WK + ++ + + F+ ++ F E I +A + K Y NP++
Sbjct: 3324 ICLLL---GESTTD--WKQIRSIIMR-ENFIPTIVNFSAEEISDAIREKMKKNYMSNPSY 3377
Query: 3235 DPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKI 3294
+ E + S A + W I + + ++ V P R L++ + + Q+K + ++ I
Sbjct: 3378 NYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMI 3437
Query: 3295 AELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFR 3354
+L A+++ + +E + + A + + L+ L++E RW ++ E F+
Sbjct: 3438 RDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFK 3497
Query: 3355 SQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLK-VPIPITNGLDPLSLL 3413
+Q T+ GD LL +AF++Y GYF ++ R L + + H+L+ I + L
Sbjct: 3498 NQMSTIAGDCLLSAAFIAYAGYFDQQMRQNL----FTTWSHHLQQANIQFRTDIARTEYL 3553
Query: 3414 TDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRL 3473
++ + W LP+D + TENA +L R+PLI+D Q ++I N+Y+ ++
Sbjct: 3554 SNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDR----KI 3609
Query: 3474 GQKSYLDV-----IEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGK--YIKIGDKE 3526
+ S+LD +E A+ G+ LL++++ E+ DPVL+P+L R + G I +GD++
Sbjct: 3610 TRTSFLDDAFRKNLESALRFGNPLLVQDV-ESYDPVLNPVLNREVRRTGGRVLITLGDQD 3668
Query: 3527 VEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLK 3586
++ P F + L T+ + P++ ++ T +NF VTR L+ Q L V+ ERPD+++ +
Sbjct: 3669 IDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKR 3728
Query: 3587 ANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAK 3646
++L K Q EF++ L++LE SLL L+ G L D ++ LE K A+E+ KV E
Sbjct: 3729 SDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETD 3788
Query: 3647 ITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANE 3706
I ++ + Y P + S +YF + L +I+ +YQ+SL+ F ++ +
Sbjct: 3789 IVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLKG 3848
Query: 3707 V---KQRVINLTDEITYSVYMYTARGLFERDKLIF---LAQVTFQVLSMKKELNPVELDF 3760
V QR+ +T ++ + ARG+ +D + F LA++ + ++ + E
Sbjct: 3849 VTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKG-TVGEPTYDAEFQH 3907
Query: 3761 LLR---FPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAP 3817
LR AG + L + + LS + FK+L + ++ +++ ++S +P
Sbjct: 3908 FLRGNEIVLSAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQAD-EQFGIWLDSSSP 3966
Query: 3818 EKEIFPKEWKNKT-------ALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEF 3870
E+ + P W +T A+ +L +++ RPDR+ FV +G F+
Sbjct: 3967 EQTV-PYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPL 4025
Query: 3871 SKSY---EESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEV-VA 3926
++ E P+T + PG D VE L + N ++ ++++G + A
Sbjct: 4026 DLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAE-----QNTQITSIAIGSAEGFNQA 4080
Query: 3927 ENALDVAAEKGHWVILQNIHLVARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHI 3986
+ A++ A + G WV+L+N+HL WL L+KKL +S H +R+F++ E P
Sbjct: 4081 DKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKL--HSLQPHACFRLFLTMEINPK----- 4133
Query: 3987 IPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVA 4046
+P +L EPP G+ AN+ + + +C E + F L +FHA++
Sbjct: 4134 VPVNLLRAGRIFVFEPPPGVKANMLRTFS--SIPVSRICKSPNERARLYFLLAWFHAIIQ 4191
Query: 4047 ERRKFGAQGWNRSYPFNNGDLTISINVLYNYLE---------ANPKVPWDDLRYLFGEIM 4097
ER ++ GW++ Y F DL + + + +L+ + K+PW L+ L + +
Sbjct: 4192 ERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSI 4251
Query: 4098 YGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLA------PGFQIPPNLDYKGYHEYIDE 4151
YGG + +++D+RL T+L T + + LA Q+P + + + ++++
Sbjct: 4252 YGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVEL 4311
Query: 4152 NLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKE---------------TDSGAG 4196
++P GL NAE LT + +L+MQ E TDS +
Sbjct: 4312 LPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRTDSTSD 4371
Query: 4197 TGVSREEKVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRS 4256
+ + + L IP+T + + + K P +E + L ++R+
Sbjct: 4372 GRPAWMRTLHTTASNWLHLIPQTLSHLKRTVENI-KDPLFRFFEREVKMGAKLLQDVRQD 4430
Query: 4257 LKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELE 4316
L ++ +G+ T + L L +P +W P+ M + W +D RI++L+
Sbjct: 4431 LADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQ 4490
Query: 4317 AWTTDFALPTT-------VWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNR 4369
+ A V L G F P++++TA Q +A+ N W L+++CL V VT
Sbjct: 4491 NISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQG 4550
Query: 4370 EDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETK-N 4428
+ A V GL ++GA + ++ A ++ A+P+ ++ + E K +
Sbjct: 4551 ATLDAC---SFGVTGLKLQGATCNNNKLSLSNA----ISTALPLTQLRWVKQTNTEKKAS 4603
Query: 4429 IYECPVYKTRIRGP-TYVWTFNLKTKEKAAKWILAAVALL 4467
+ PVY R + F + TKE + VA+L
Sbjct: 4604 VVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAVL 4643
Score = 48.9 bits (115), Expect = 1e-04
Identities = 123/642 (19%), Positives = 257/642 (40%), Gaps = 68/642 (10%)
Query: 186 DNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKCIHEQL 245
D L+ +++ + W +I+ V D A L E FW L I E+
Sbjct: 238 DPTFLNQLQSGVNRWIREIQKVTKLDRDPASGTALQ-----EISFWLNLERALYRIQEKR 292
Query: 246 NRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLK--PLRILLEEMEQAD 303
P+V ++IL+ K + + T + + L+ ND +K PL LL E
Sbjct: 293 ESPEVLLTLDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATE--- 349
Query: 304 FTMLPTFIAKVLDTICFIWATSEYYNTPARII-VILQEFCNQIIEMTRTFLSPEEVLKGL 362
+ + + + I T R++ I ++ +Q++++ L +++
Sbjct: 350 LDKIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKV----LGTRKLMHVA 405
Query: 363 QGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSFFQ 422
E E+V+ E++QT+D +++ +D E + + RIN +
Sbjct: 406 YEEFEKVMVACF-------EVFQTWDDEYEKLQVLLRDIVKRKREENLKMVW-RINPAHR 457
Query: 423 RIQT-IEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKV-FADCKYDPLD 480
++Q ++++ K + +L + + +R + ++ + EV E + A+ +D D
Sbjct: 458 KLQARLDQMRKFRRQHEQLRAVIVRVLRPQVT-AVAQQNQGEVPEPQDMKVAEVLFDAAD 516
Query: 481 PG---------DSVGPRAGLDELDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIK 531
++V GLD + A + + +DR I + D K
Sbjct: 517 ANAIEEVNLAYENVKEVDGLDVSKEGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAK 576
Query: 532 SSAKLLYMCG---GLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIP 588
++ ++ + L RP I + + +++ ++++ + Q S+ +
Sbjct: 577 NANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMS 636
Query: 589 LIHKNMPPVAGQLKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLR-- 646
+ +++PPV+G + W+ ++ +L ++K VE + G E + QK + + R
Sbjct: 637 HV-RDLPPVSGSIIWAKQIDRQLTA---YMKRVEDVLGKGWENHVEGQKLKQDGDSFRMK 692
Query: 647 CHREKIYQQWVAGVDQDCHFNLG--------QPLILRDAASNL--IHVNFSKALVAVLRE 696
+ ++I+ W V Q NLG + +R N+ + VNF ++ + +E
Sbjct: 693 LNTQEIFDDWARKVQQR---NLGVSGRIFTIESTRVRGRTGNVLKLKVNFLPEIITLSKE 749
Query: 697 V---KYLNFQQQKEIPDSAESLFSENETFRKFVGNLELIVGWYNEVMKAVE----FLLIK 749
V K+L F+ I + A N+ + F +L V Y + VE L+
Sbjct: 750 VRNLKWLGFRVPLAIVNKAH---QANQLY-PFAISLIESVRTYERTCEKVEERNTISLLV 805
Query: 750 SELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQNRM 791
+ L+ L++ L W + Y+Q + E + N Q ++
Sbjct: 806 AGLKKEVQALIAEGIALVWESYKLDPYVQRLAETVFNFQEKV 847
>gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sapiens]
Length = 798
Score = 1236 bits (3198), Expect = 0.0
Identities = 575/798 (72%), Positives = 689/798 (86%)
Query: 3673 LNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFE 3732
+NDL+KI+P+YQFSLKAF++VF+KA++R P +++RV NL D IT+SVY YT RGLFE
Sbjct: 1 MNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFE 60
Query: 3733 RDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMD 3792
DKL +LAQ+TFQ+L M +E+N VELDFLLR P + G SPV+FL HQ WG +K LS M+
Sbjct: 61 CDKLTYLAQLTFQILLMNREVNAVELDFLLRSPVQTGTASPVEFLSHQAWGAVKVLSSME 120
Query: 3793 EFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKN 3852
EF NLD DIEGSAK WKK VESE PEKE P+EWKNKTALQ+LCM+R +RPDRMTYA+++
Sbjct: 121 EFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNKTALQRLCMLRAMRPDRMTYALRD 180
Query: 3853 FVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGK 3912
FVEEK+GSK+V GR+++F+ S+EES P+T +FFILSPGVDPLKDVE+ G+KLG+T +N
Sbjct: 181 FVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQN 240
Query: 3913 LHNVSLGQGQEVVAENALDVAAEKGHWVILQNIHLVARWLGTLDKKLERYSTGSHEDYRV 3972
HNVSLGQGQEVVAE ALD+AA+KGHWVILQNIHLVA+WL TL+KKLE +S SH ++RV
Sbjct: 241 FHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEEHSENSHPEFRV 300
Query: 3973 FISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFK 4032
F+SAEPAPSPE HIIPQGILEN+IKITNEPPTGMHANLHKALD FTQDTLEMC++E EFK
Sbjct: 301 FMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCSRETEFK 360
Query: 4033 CMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYL 4092
+LFALCYFHAVVAERRKFG QGWNRSYPFN GDLTIS+NVLYN+LEAN KVP+DDLRYL
Sbjct: 361 SILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPYDDLRYL 420
Query: 4093 FGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDEN 4152
FGEIMYGGHITDDWDRRLCRTYL E+IR EMLEG++ LAPGF +P N+DY GYH+YID
Sbjct: 421 FGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEGELSLAPGFPLPGNMDYNGYHQYIDAE 480
Query: 4153 LPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKVKAVLDDI 4212
LPPESPYLYGLHPNAEIGFLT TSEKLFRTVLE+QP+++ + G G +REEKVKA+L++I
Sbjct: 481 LPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVKALLEEI 540
Query: 4213 LEKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITT 4272
LE++ + FN+ E+MAK E+TPY+VVAFQEC RMNILT E++RSL+EL LGLKGELT+T+
Sbjct: 541 LERVTDEFNIPELMAKVEERTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTS 600
Query: 4273 DVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAG 4332
+E+L AL++D VP++W RAYPS GLAAW+ DLL RI+ELEAWT DF +P+TVWL G
Sbjct: 601 HMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTG 660
Query: 4333 FFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARW 4392
FFNPQSFLTAIMQS ARKNEWPLD+M L ++TKKNRE+ +PPREG+Y++GLFMEGA W
Sbjct: 661 FFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACW 720
Query: 4393 DTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKT 4452
DTQ G+I EA+LK+LTP MPV+FIKAIP D+ + +++Y CPVYKT RGPTYVWTFNLKT
Sbjct: 721 DTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQRGPTYVWTFNLKT 780
Query: 4453 KEKAAKWILAAVALLLQV 4470
KE +KW+LA VALLLQ+
Sbjct: 781 KENPSKWVLAGVALLLQI 798
>gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens]
Length = 4314
Score = 1186 bits (3068), Expect = 0.0
Identities = 951/3531 (26%), Positives = 1657/3531 (46%), Gaps = 258/3531 (7%)
Query: 1071 LQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDG 1130
L +C P K + I++ + L + L +++ F+ A LT + +
Sbjct: 908 LNINCNPVKTVIDDLIQKLFDLLVLSLKKSIQAHLHEIDTFVTEAMEVLT--IMPQSVEE 965
Query: 1131 LVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKL 1190
+ + K++ER+ +F+ + LL+T E I + + +
Sbjct: 966 IGDANLQYSKLQERKPEILPLFQEAEDKNRLLRTVAGGGLETISNLKAKWDKFELMMESH 1025
Query: 1191 AIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFS-FSDPNPYKSLNKQQK 1249
+ +K + ++ N S L+ Q+ E +F+ R+ + P + + +L+K K
Sbjct: 1026 QLMIKDQIEVMKGNVKSRLQIYYQELE----KFKARWDQLKPGDDVIETGQHNTLDKSAK 1081
Query: 1250 SISA-------MEGIMEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSI 1302
I +E + L F + P++ + +++ ++W
Sbjct: 1082 LIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSISKDIESCAQIWAFYEEFQQGF 1141
Query: 1303 -----EDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLR 1357
EDW T + K E+ ++ + +R +++ + K VI L+
Sbjct: 1142 QEMANEDWITFRTKTYLFEEFLMN---WHDRLRKVEEHSVMTVKLQSEVDKYKIVIPILK 1198
Query: 1358 AVSELQNPAIRERHWQQLMQATQVKFKMSEETTL-ADLLQL--NLHSYEDEVRNIVDKAV 1414
V + + HW L + + S E L DLL++ + + +++++ +A
Sbjct: 1199 YV---RGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQ 1255
Query: 1415 KESGMEKVLKALD-----STWSMMEFQHEPHPRTGTMMLKSSEVLVETLEDNQVQLQNLM 1469
E + + L+ LD + +++++++ + RT ++K + +V + DN+ LQ+L
Sbjct: 1256 GEVTIREALRELDLWGVGAVFTLIDYE-DSQSRT-MKLIKDWKDIVNQVGDNRCLLQSLK 1313
Query: 1470 MSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRF 1529
S Y F +V+ W++KL+ D + +QR W +LE IF R LP + RF
Sbjct: 1314 DSPYYKGFEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFG-----RGALPKEQTRF 1368
Query: 1530 DDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPR 1589
+ ++++F+++M D K V T+ G+ N L + L C+K+L E+LE KR AFPR
Sbjct: 1369 NRVDEDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQKSLNEFLEEKRSAFPR 1428
Query: 1590 FYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEY 1649
FYF+ DLL+IL +P + HL KLF + + F D+ K M S E E
Sbjct: 1429 FYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCF-----DEKSKHITAMKSLEGEV 1483
Query: 1650 MVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPREQWILDYPAQVALTCT 1709
+ F + LS VE WLN + M TL + E V T +P+Q+
Sbjct: 1484 VPFKNKVPLSNNVETWLNDLALEMKKTLEQLLKECVTTGRSSQGAVDPSLFPSQILCLAE 1543
Query: 1710 QIWWTTEVGLAFARLEEGYENAIRDYNKKQISQLNVLITLLM------------GNLNAG 1757
QI +T +V ENAI+D++ QI L+ L GN +G
Sbjct: 1544 QIKFTEDV-----------ENAIKDHSLHQIE--TQLVNKLEQYTNIDTSSEDPGNTESG 1590
Query: 1758 D-RMKIMTICTIDVHARDVVAKMIVAKVESSQAFTWQAQLRHRWDEEKRHCFANICDAQI 1816
+K+ + +H DVV ++ +V +++ + W+ QLR + + C + D++
Sbjct: 1591 ILELKLKALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRF-YMKSDHTCCVQMVDSEF 1649
Query: 1817 QYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTM 1876
QY+YEY GN +LV TPLTD+CY+TLTQ++ + +GG P GPAGTGKTE+ K LG LG
Sbjct: 1650 QYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQ 1709
Query: 1877 VYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKK 1936
V VFNC E +D KS G I+ GL + GAWGCFDEFNR+ VLS +++Q++ +QDA++ +
Sbjct: 1710 VLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALKNHR 1769
Query: 1937 KAFNFLGEIIGLIPTVGIFITMNP---GYAGRAELPENLKALFRPCAMVVPDFELICEIM 1993
LG+ + + GIFITMNP GY GR +LP+NLK LFRP AM PD ELI E++
Sbjct: 1770 TVCELLGKEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIAEVI 1829
Query: 1994 LMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSL-----KRGDP 2048
L +EGF +A++L+RK + ++ L +ELL+ Q HYDWGLRA+K+VL +G+L K G
Sbjct: 1830 LYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLNKSGTT 1889
Query: 2049 SRA-EDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVE 2107
A E ++++ALR + K D F LI D+FP +++ +KQ E
Sbjct: 1890 QNANESHIVVQALRLNTMSKFTFTDCTRFDALIKDVFPGIELKEVEYDELSAALKQVFEE 1949
Query: 2108 LKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLD 2167
+ + + K ++L E L R V IVG +G+GKS + + L + ++
Sbjct: 1950 ANYEIIPNQIKKALELYEQLCQRMGVVIVGPSGAGKSTLWRMLRAALCKTGKVVKQYTMN 2009
Query: 2168 PKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTV 2227
PKA+ +L G I+ TREW DG+ + R + D WII DGDIDP WIESLN+V
Sbjct: 2010 PKAMPRYQLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDIDPEWIESLNSV 2069
Query: 2228 MDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSW 2287
+DDN++LT+ S ERI + VFE L A+PAT+SR G+++++ + N ++ SW
Sbjct: 2070 LDDNRLLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSW 2129
Query: 2288 IERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEKTV 2347
+ R + + NL Y L++ K+ V E +++ T++ L L
Sbjct: 2130 L-RNQPAEYRNNLENWIGDYFEKA---LQWVLKQNDYVVETSLVGTVMNGLSHL------ 2179
Query: 2348 PPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYY 2407
R+ E F+ GG + +++ E W P D Y
Sbjct: 2180 --HGCRDHDE--FIINLIRGLGGNLNMKSRLEFTKEVFHWARESPPDFHKP-----MDTY 2230
Query: 2408 IDPDTKKFLPWTDKVPSFELDPDVP--LQASLVHTTETIR-IRYFMD-LLMEKSWPVMLV 2463
D + + K P D L ++ T + R + YF L + P +LV
Sbjct: 2231 YDSTRGRLATYVLKKPEDLTADDFSNGLTLPVIQTPDMQRGLDYFKPWLSSDTKQPFILV 2290
Query: 2464 GNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKP---LEKKSGRNYGP 2520
G G GK +L+ L + + V + TTS L L + + +GR Y P
Sbjct: 2291 GPEGCGKGMLLRYAFSQLRSTQ--IATVHCSAQTTSRHLLQKLSQTCMVISTNTGRVYRP 2348
Query: 2521 PGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMN 2580
++LV ++ D+N+P++DK+GT ++Q + ++ +YD + L + N Q VA M+
Sbjct: 2349 KDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDEN-LEWVGLENIQIVASMS 2407
Query: 2581 PTS--GSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQ-- 2636
G + +R + ++ +P +E L TIY L L + +I SS+
Sbjct: 2408 AGGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLHKNLKNHSIWGSSSKIY 2467
Query: 2637 -LVAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAE--VLKTPLDLV-RL 2692
L + + +++++ A F HY F L+ GL E PLD V +
Sbjct: 2468 LLAGSMVQVYEQVRAKFTVDDYS-HYFFTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEI 2526
Query: 2693 WLHETERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFC------HFAQ 2746
+E R++ DK+V K+ LH + T F D G ++L + F H +
Sbjct: 2527 VAYEARRLFRDKIVGAKE---LHLFDIILTSVFQGDWGSDILDNMSDSFYVTWGARHNSG 2583
Query: 2747 GIGDPKYVPVTDMAPLNKL----LVDVLDS----YNEVNAVMNLVLFEDAVAHICRINRI 2798
P PL KL L DV+ Y N ++++LF + + ++ RI+R+
Sbjct: 2584 ARAAPGQPLPPHGKPLGKLNSTDLKDVIKKGLIHYGRDNQNLDILLFHEVLEYMSRIDRV 2643
Query: 2799 LESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAV 2858
L P G+ LL G G G+++++ L +++ G +F + +GY + K DL A +
Sbjct: 2644 LSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRGYELKQFKNDLKHVLQLAGI 2703
Query: 2859 KNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDT 2918
+ V L+ D Q FL +IN LL+SGE+PGL+ +E+E ++ ++ Q G
Sbjct: 2704 EAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEELEPLLLPLKDQASQDGFFG- 2762
Query: 2919 RETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVS 2978
+ +F ++++ L ++L S + PA+ + W W ++ +
Sbjct: 2763 --PVFNYFTYRIQQNLHIVLIMDSANSNFMINCESNPALHKKCQVLWMEGWSNSSMKKIP 2820
Query: 2979 ARFLEETEGIPVI----------KASI--SFFMSYVHTTVNEMSRVYLATERRYNYTTPK 3026
ET G K S+ F S++ ++E + Y AT RY
Sbjct: 2821 EMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFL--LIHESCKAYGATPSRY-----M 2873
Query: 3027 TFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNE 3086
TFL +Y + + K+ EL+ + L+ G+ KL + VD+L K Q LK K +
Sbjct: 2874 TFLH---VYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQD 2930
Query: 3087 SADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQE 3146
AD +Q++ + + S++K ++ + ++ + E++ + +L + +P + A+
Sbjct: 2931 EADAALQMITVSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKL 2990
Query: 3147 ALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFL 3206
A+ + +L+E++S PPD + ++ V+ L D SW + K + K
Sbjct: 2991 AVGNIKPESLSEIRSLRMPPDVIRDILEGVLRLMG-----IFDTSWVSMKSFLAKRGV-R 3044
Query: 3207 DSLKKFDKEHIPEACLKAFKP--YQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYC 3264
+ + FD +I + ++ + ++ +FDP+ + STAAA L +W +++ V
Sbjct: 3045 EDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLE 3104
Query: 3265 DVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADA 3324
+ P + L + +++ +++ + + +S L F+ T+E K + E
Sbjct: 3105 RIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSK 3164
Query: 3325 TNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNE 3384
I A L+ L E+ RW V + TL L +AF++Y+ + R
Sbjct: 3165 AQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAAFITYLSAAPESLRKT 3224
Query: 3385 LMEKFWIPYIHNLKVPIPITNGLDPLSL---LTDDADVATWNNQGLPSDRMSTENATI-- 3439
+E+ W + GL+ L L +++ W ++GLPSD +S ENA +
Sbjct: 3225 CLEE-WTK-----------SAGLEKFDLRRFLCTESEQLIWKSEGLPSDDLSIENALVIL 3272
Query: 3440 -LGNTERW----PLIVDAQLQGIKWIKNKYR-SELKAIRLGQKSYLDVIEQAISEGDTLL 3493
+ + W P ++D Q +W+K + S L+ I +++ +E A+ G TL+
Sbjct: 3273 QIIGLKSWSRVCPFLIDPSSQATEWLKTHLKDSRLEVINQQDSNFITALELAVRFGKTLI 3332
Query: 3494 IENIGETVDPVLDPLLGRNTIKKGK--YIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQ 3551
I+ + + V+PVL PLL R+ + +G ++IGDK ++Y+ +FRL L T+ NP P+
Sbjct: 3333 IQEM-DGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLSTRNPNPFIPPDAA 3391
Query: 3552 AQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARL 3611
+ T +NF TR GL QLLA + E+PDLE+ K L + + + KI L +LE+SLL L
Sbjct: 3392 SIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETL 3451
Query: 3612 SAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYF 3671
+ + GN L + L+E+L TK +++ I+E + E+ ++ +++ R+ Y P AE AS +YF
Sbjct: 3452 ATSQGNILENKDLIESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLAESASKMYF 3511
Query: 3672 ILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLF 3731
I++DL+KIN +Y+FSL AF +F++A+Q + +QR+ +L + + VY Y R LF
Sbjct: 3512 IISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYEYICRCLF 3571
Query: 3732 ERDKLIFLAQVT-------FQVLSMKKELNPVELDFLLRFPFKAGVVS--PVDFLQHQGW 3782
+ D+L+F FQ V D L + + + P Q + W
Sbjct: 3572 KADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQERSW 3631
Query: 3783 G-GIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTAL-QKLCMVRC 3840
++ ++ L + A W+ + E+E FP K +L Q++ +V+
Sbjct: 3632 AVATLKIALPSLYQTLCFE---DAALWRTYYNNSMCEQE-FPSILAKKVSLFQQILVVQA 3687
Query: 3841 LRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEAL 3900
LRPDR+ A+ F + +G K V + + Y+E+ I I+SPG DP ++++ L
Sbjct: 3688 LRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYKETLEIEPILIIISPGADPSQELQEL 3747
Query: 3901 GKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQNIHLVARWLGTLDKKLE 3960
H V++GQGQ +A L A G W+ L+N+HLV WL L+K+L
Sbjct: 3748 ANA---ERSGECYHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELN 3804
Query: 3961 RYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQD 4020
+ + +R++++AE P+ +L++++KIT E P G+ NL + + +T +
Sbjct: 3805 --TLQPKDTFRLWLTAEVHPN-----FTPILLQSSLKITYESPPGLKKNLMRTYESWTPE 3857
Query: 4021 TLEMCTKEMEFKC-MLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLE 4079
++ K+ + LF+L +FHA ERR + QGW + Y F+ DL N++ +
Sbjct: 3858 --QISKKDNTHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFD 3915
Query: 4080 ANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLE------GDVLLAPG 4133
V W+ + L +YGG I + +D R+ ++YL ++ + +++ +
Sbjct: 3916 GAKDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVIDVFNQRNKKSIFPYS 3975
Query: 4134 FQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLF--RTVLEMQPKET 4191
+P + Y I++ + P +GL N + +S+++ + + +++
Sbjct: 3976 VSLPQSCSILDYRAVIEKIPEDDKPSFFGLPAN-----IARSSQRMISSQVISQLRILGR 4030
Query: 4192 DSGAGTGVSRE---EKVKAVLDDILEKIPETFNMA-EIMAKAAEKTPYVVVAFQECERMN 4247
AG+ RE ++ VL ++ +K+ + N+ + + ++ +++F E+ N
Sbjct: 4031 SITAGSKFDREIWSNELSPVL-NLWKKLNQNSNLIHQKVPPPNDRQGSPILSFIILEQFN 4089
Query: 4248 I--LTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWY 4305
L + +SL L+ ++G ++++V+ L++AL P W ++ + +
Sbjct: 4090 AIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLAWQSK-WEGPEDPLQYL 4148
Query: 4306 ADLLLRIRELEAWT----TDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLS 4361
L+ R ++ W L T+ L+ F+P +FL A+ Q AR +D +
Sbjct: 4149 RGLVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKFV 4208
Query: 4362 VEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPV 4421
+ +E + + GL +EG +D + ++ +P F+ IP
Sbjct: 4209 ASWKGRLQE-----AKLQIKISGLLLEGCSFDGNQLSENQLDSPSVSSVLP-CFMGWIPQ 4262
Query: 4422 DRMETKNIYEC---PVYKTRIRGPTYVWTFNLKTKEKAAKWILAAVALLLQ 4469
D + EC PVY T V ++ +WI AL L+
Sbjct: 4263 DACGPYSPDECISLPVY-TSAERDRVVTNIDVPCGGNQDQWIQCGAALFLK 4312
Score = 38.1 bits (87), Expect = 0.20
Identities = 50/273 (18%), Positives = 118/273 (43%), Gaps = 27/273 (9%)
Query: 543 LMERPLILAEVA-PRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQL 601
L++RP I E+ R +++ L D+ D + + + PL KN+ V +
Sbjct: 427 LVKRPTISKELMLERETLLARLVDSIKDFRLDFENRCRGIPGDASGPLSGKNLSEVVNSI 486
Query: 602 KWSLELQERLEVSMKHLKHVEHPVMSGAEA-KLTYQKYDEMMELLRCHREKIYQQWVAGV 660
W +L+ +++ ++K + ++S + +Q ++++ L+ + ++ + W +
Sbjct: 487 VWVRQLELKVDDTIK----IAEALLSDLPGFRCFHQSAKDLLDQLKLYEQEQFDDWSRDI 542
Query: 661 DQDCH-------FNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAE 713
++ D+ L+ V++S LV +LREV+ L+ IP +
Sbjct: 543 QSGLSDSRSGLCIEASSRIMELDSNDGLLKVHYSDRLVILLREVRQLS-ALGFVIPAKIQ 601
Query: 714 SLFSENETFRKFVGNLELIVGWYN----EVMKAVEFLLIKSELEAIDVKLLS-----AET 764
+ + + F K L+ + +YN +++++ ++++S L + S ++
Sbjct: 602 QVANIAQKFCKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIKNSKAGSGGKS 661
Query: 765 TLFWNG----EGVFQYIQEVREILHNLQNRMQK 793
+ W+ EG Q +Q E L +++K
Sbjct: 662 QITWDNPKELEGYIQKLQNAAERLATENRKLRK 694
>gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens]
Length = 3092
Score = 976 bits (2523), Expect = 0.0
Identities = 657/2074 (31%), Positives = 1047/2074 (50%), Gaps = 200/2074 (9%)
Query: 901 DESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDRMN 960
D+ P+F+I + D+D + F PT + D L+L+E + + NV + L+
Sbjct: 319 DQQRLPIFKIELTFDDDKMEFYPTFQDLED-NVLSLVERIAEALQNVQTIPSWLSGTSTP 377
Query: 961 YKMDLEDNTDLIEMREEVSSLVINAMKEA--EEYQDSFERYSYLWTDNLQEFMKNFLIYG 1018
+D E ++ + ++ E + Y+ E+Y N+L+ G
Sbjct: 378 VNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKY-------------NWLLDG 424
Query: 1019 CAVTAEDLDTW-TDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRP 1077
AV E+++T+ T+D T ++ E I+ + L E+ + + ++ DC
Sbjct: 425 TAV--ENIETFQTED------HTFDEYTEFIEKFLSLASEIMLLPQW-IHYTMVRLDCED 475
Query: 1078 FKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGD--YDGLVEVM 1135
K L + + + +N + N +A +K KE + +
Sbjct: 476 LKTGLTNKAKAF--------ANILLNDIA-------------SKYRKENECICSEFEAIK 514
Query: 1136 GHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWA--------NT 1187
H +KV E T+ M + L +E +T G EE+ L++QE +
Sbjct: 515 EHALKVPE---TTEEMMD-LISYVEKARTVG---IEELILRIQESKRQMSYFLDVFLFPQ 567
Query: 1188 KKLAIQVKLTVAPLQANEV---------SILRRKCQQFELKQHEF-----RERFRREAPF 1233
+ LA+ + + P + N + + +K + K+ + +E R E
Sbjct: 568 EDLALNATVLMWPRKINPIFDENDELIENAKHKKENELMAKREKLILEIEKESRRMEEFT 627
Query: 1234 SFSDPNPYK----SLNKQQKSISAMEGIMEALSKSGGLFEVPVPDYKQLKACHREVRLLK 1289
F++ + + + QK I E ++ ++K LF+ + Y +L + +
Sbjct: 628 EFAELERMQQYVTDVRQLQKRIQESEEAVQFINKEEELFKWELTKYPELDKLKVNIEPYQ 687
Query: 1290 ELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTV 1349
+ ++ V+ S + W + D+N E M+ D ++F+ R + K +K + + +
Sbjct: 688 KFFNFVLKWQRSEKRWMDGGFLDLNGESMEADVEEFS---REIFKTLKFFQTKLKKELQE 744
Query: 1350 KNVITSLRAVSE------------LQNPAIRERHWQQLMQATQVKFKMSEETTLADLLQL 1397
K R++ E + +R RHW+Q+ + TTL +L+L
Sbjct: 745 KRKAARKRSLEEEKIEEEPKDNATITMCRMRARHWKQISEIVGYDLTPDSGTTLRKVLKL 804
Query: 1398 NLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEVLVET 1457
NL Y ++ I A KE +EK + + TW + F + TG +L S + +
Sbjct: 805 NLTPYLEQFEVISAGASKEFSLEKAMNTMIGTWEDIAFHISLYRDTGVCILSSVDEIQAI 864
Query: 1458 LEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSED 1517
L+D ++ Q + S ++ F E+ +W+ +L I W +VQ W +LE IF SED
Sbjct: 865 LDDQIIKTQTMRGSPFIKPFEHEIKAWEDRLIRIQETIDEWLKVQAQWLYLEPIFC-SED 923
Query: 1518 IRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALA 1577
I Q+P + ++F +++ ++ +M+ K P V+ ATS GL KL+ + L K L
Sbjct: 924 IMQQMPEEGRQFQTVDRHWRDIMKFCAKDPKVLAATSLTGLLEKLQNCNELLEKIMKGLN 983
Query: 1578 EYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLK 1637
YLE KRL FPRF+F+S+ ++L+ILS DP+ V HL K F+ + KL+F + K
Sbjct: 984 AYLEKKRLFFPRFFFLSNDEMLEILSETKDPLRVQPHLKKCFEGIAKLEFLPNLDIK--- 1040
Query: 1638 VGLGMYSKEDEYMVFDQECDLS---GQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPRE 1694
MYS E E + S G VE WL +V D M ++ I A + Y E R
Sbjct: 1041 ---AMYSSEGERVELIALISTSAARGAVEKWLIQVEDLMLRSVHDVIAAARLAYPESARR 1097
Query: 1695 QWILDYPAQVALTCTQIWWTTEVGLAFARLEEGYENAIRDYNKKQISQLNVLITLLMGNL 1754
W+ ++P QV L +Q++WT+E + EG ++ Y K+ +QLN ++ L+ G L
Sbjct: 1098 DWVREWPGQVVLCISQMFWTSETQEVISGGTEG----LKKYYKELQNQLNEIVELVRGKL 1153
Query: 1755 NAGDRMKIMTICTIDVHARDVVAKMIVAKVESSQAFTWQAQLRHRWDEEKRHCFANICDA 1814
+ R + + TIDVHARDVV MI V F W AQLR+ W+ E I +
Sbjct: 1154 SKQTRTTLGALVTIDVHARDVVMDMIKMGVSHDTDFLWLAQLRYYWENENAR--VRIINC 1211
Query: 1815 QIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALG 1874
++Y+YEYLGN+PRLVITPLTDRCY TL + +L +GGAP GPAGTGKTETTKDL +AL
Sbjct: 1212 NVKYAYEYLGNSPRLVITPLTDRCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALA 1271
Query: 1875 TMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRA 1934
VFNCS+ +DY + G +KGLA +GAW CFDEFNRI +EVLSV+A Q+ C+Q AI+
Sbjct: 1272 VQCVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSVVAQQILCIQRAIQQ 1331
Query: 1935 KKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIML 1994
K F F G + L P + ITMNPGYAGR+ELP+NLK LFR AM+VP++ LI EI L
Sbjct: 1332 KLVVFVFEGTELKLNPNCFVAITMNPGYAGRSELPDNLKVLFRTVAMMVPNYALIAEISL 1391
Query: 1995 MAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQ 2054
+ GFL AR L+ K + Y LC E LS Q HYD+G+RA+K+VLV AG+LK P+ ED
Sbjct: 1392 YSYGFLNARPLSVKIVMTYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNLKLKYPNENEDI 1451
Query: 2055 VLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAED 2114
+L+R+++D N PK ++ D+P+F G+ DLFP + +P F + ++ LQ
Sbjct: 1452 LLLRSIKDVNEPKFLSHDIPLFNGITSDLFPGIKLPEADYHEFLECAHEACNVHNLQPVK 1511
Query: 2115 SFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNL-------KRKPVAVDLD 2167
F+ K++Q E++ VRH +VG + K++VL L T + + K + ++
Sbjct: 1512 FFLEKIIQTYEMMIVRHGFMLVGEPFAAKTKVLHVLADTLTLMNEHGYGEEEKVIYRTVN 1571
Query: 2168 PKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTV 2227
PK++T +LFG +PV+ EW DG+ + R+ A KW++ DG ID +WIES+NTV
Sbjct: 1572 PKSITMGQLFGQFDPVSHEWTDGIVANTFREFALSETPDRKWVVFDGPIDTLWIESMNTV 1631
Query: 2228 MDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSW 2287
+DDNK L L S E I ++ M L+FE L A+PATVSR G++Y+ P+ LGW P+VSSW
Sbjct: 1632 LDDNKKLCLMSGEIIQMSPQMSLIFETMDLSQASPATVSRCGMIYLEPSQLGWEPLVSSW 1691
Query: 2288 IERRK----VQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLT 2343
+ K +A L LF +P L++ R ++ + T++ IL +L
Sbjct: 1692 LNSLKGPLCEPEYQALLRGLFAWLIPPSLNQ-RVELFQLNYL-YTTIVSKILKILITFRI 1749
Query: 2344 E---KTVPPDSPRELYELY------FVFTCFWAFGGAMFQD--QLVDYRVEF-------- 2384
K VP + + + F+F+ W+ GG+ D ++ D +
Sbjct: 1750 SNYFKYVPLKTQCTFIKFFLHQQACFIFSLIWSIGGSCDTDGRRVFDTFIRLIILGKDDE 1809
Query: 2385 -------SKWWINEFKTIKFPSQGTIFDYYIDPDTK-KFLPWTDKVPSFEL-DPDVPLQA 2435
KW F +G ++DY + K +++ W + + + L D + +Q
Sbjct: 1810 NPVPDSVGKW------ECPFDEKGLVYDYMYELKNKGRWVHWNELIKNTNLGDKQIKIQD 1863
Query: 2436 SLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKL-ESLNTDNYLVQAVPFN 2494
+V T +TIR + MDL + + P++ VG GTGKSV + DKL L D Y + +
Sbjct: 1864 IIVPTMDTIRYTFLMDLSITYAKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYINLS 1923
Query: 2495 FYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHM 2554
T++ +Q ++ L+K+ +GPP KK + FIDDMNMP ++KYG P L+RQ
Sbjct: 1924 ARTSANQVQNIIMARLDKRRKGVFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLRQFF 1983
Query: 2555 DHRHWY---DRHKLTLKDIHNCQYVACMNPTSGSFT-IDSRLQRHFCVFAVSFPGQEALT 2610
D HWY D K+TL DI + +A M P G + R RHF + +++ E +
Sbjct: 1984 DCGHWYDLKDTSKITLVDI---ELIAAMGPPGGGRNPVTPRCIRHFNICSINSFSDETMV 2040
Query: 2611 TIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYVFNLRDLSN 2670
I+++I+ +L I +Q+V + ++++ LPT K HY FNLRD S
Sbjct: 2041 RIFSSIVAFYLRTHEFPPEYFVIGNQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSR 2100
Query: 2671 IFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTKKFFDDLG 2730
+ +G L + + ++RL++HE RV+ D+++++ D+ L ++T K F +
Sbjct: 2101 VIRGCLLIERDAVANKHTMIRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKE-- 2158
Query: 2731 DELLFAKPNIFCHFAQGIG-----------------------DPKYVPVTDMAPLNKLLV 2767
+ +IF H + D Y+ + ++ + ++
Sbjct: 2159 -----SFHSIFSHLRKQNAPVTEEDLRNLMFGDYMNPDLEGDDRVYIEIPNIHHFSDVVD 2213
Query: 2768 DVLDSYNEVNAV-MNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYI 2826
LD YN+ + MNLV+F + H+ RI R+L+ GNALLVG+GGSG+QSL+RLA +
Sbjct: 2214 QCLDEYNQTHKTRMNLVIFRYVLEHLSRICRVLKQSGGNALLVGLGGSGRQSLTRLATSM 2273
Query: 2827 SGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKN 2860
+ + +FQ + K YG+ + + D+ + +I V N
Sbjct: 2274 AKMHIFQPEISKSYGMNEWREDMKS-FIAVPVTN 2306
Score = 446 bits (1147), Expect = e-124
Identities = 271/787 (34%), Positives = 423/787 (53%), Gaps = 35/787 (4%)
Query: 3707 VKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLR--F 3764
+++R+ L D TY++Y R LFE+DKL+F + +L +KE+ EL FLL
Sbjct: 2316 LEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIEYQELMFLLTGGV 2375
Query: 3765 PFKAGVVSP-VDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFP 3823
K+ +P +LQ + W I SE F+ L W+++ +S+ P FP
Sbjct: 2376 SLKSAEKNPDPTWLQDKSWEEICRASEFPAFRGLRQHFCEHIYEWREIYDSKEPHNAKFP 2435
Query: 3824 KEW-KNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTS 3882
KN LQK+ ++RCLRPD++T AI N+V +K+G KFVE + +KSY +S+ +
Sbjct: 2436 APMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLTKSYLDSNCTIP 2495
Query: 3883 IFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVIL 3942
+ F+LSPG DP+ + ++ K +SLGQGQ +A + A E+G WV L
Sbjct: 2496 LIFVLSPGADPMASLLKFANDK--SMSGNKFQAISLGQGQGPIAAKMIKAAIEEGTWVCL 2553
Query: 3943 QNIHLVARWLGTLDKKLERYSTGS-HEDYRVFISAEPAPSPETHIIPQGILENAIKITNE 4001
QN HL W+ L+K E +++ + + +R+++++ P+ P IL+N +K+TNE
Sbjct: 2554 QNCHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSK-----FPVTILQNGVKMTNE 2608
Query: 4002 PPTGMHANLHKAL---DLFTQDTLEMCT-KEMEFKCMLFALCYFHAVVAERRKFGAQGWN 4057
PPTG+ NL ++ + + + C KE+ ++ +LF +C+FHA+V ER+KFG GWN
Sbjct: 2609 PPTGLRLNLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQERKKFGPLGWN 2668
Query: 4058 RSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAE 4117
Y FN DL ISI L ++ +P++ + YL GE YGG +TDDWDRRL T LA+
Sbjct: 2669 IPYGFNESDLRISIRQLQLFINEYDTIPFEAISYLTGECNYGGRVTDDWDRRLLLTMLAD 2728
Query: 4118 YIRTEMLEG-DVLLAP--GFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTV 4174
+ ++E +P + PP Y+ Y E+I + + P ++GLH N +I
Sbjct: 2729 FYNLYIVENPHYKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPEIFGLHENVDISKDLQ 2788
Query: 4175 TSEKLFRTVLEMQPKETDSGAGTGVSREEKVKAVLDDILEKIPETFNMAEIMAK--AAEK 4232
++ LF ++L Q +GA S ++ + + DIL K+P F++ + K +
Sbjct: 2789 QTKTLFESLLLTQGGSKQTGASG--STDQILLEITKDILNKLPSDFDIEMALRKYPVRYE 2846
Query: 4233 TPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVA 4292
V QE ER N L +R +L++L +KG + + + +E LS +L VP+ W
Sbjct: 2847 ESMNTVLVQEMERFNNLIITIRNTLRDLEKAIKGVVVMDSALEALSGSLLVGKVPEIWAK 2906
Query: 4293 RAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNE 4352
R+YPS+ L ++ D L R+ L+ W P WL+GFF Q+FLT MQ+ ARK
Sbjct: 2907 RSYPSLKPLGSYITDFLARLNFLQDWYNS-GKPCVFWLSGFFFTQAFLTGAMQNYARKYT 2965
Query: 4353 WPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMP 4412
P+D + EV + D + P +G Y++GL+++GARWD ++G++AE K L MP
Sbjct: 2966 TPIDLLGYEFEVIPSDTSDTS--PEDGVYIHGLYLDGARWDRESGLLAEQYPKLLFDLMP 3023
Query: 4413 VIFIKAIPVDRMETKNIYECPVYKTRIRGPT---------YVWTFNLKTKEKAAKWILAA 4463
+I+IK R+ + Y CP+YKT R T +V LKT + WI
Sbjct: 3024 IIWIKPTQKSRIIKSDAYVCPLYKTSERKGTLSTTGHSTNFVIAMLLKTDQPTRHWIKRG 3083
Query: 4464 VALLLQV 4470
VALL Q+
Sbjct: 3084 VALLCQL 3090
>gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [Homo
sapiens]
Length = 4515
Score = 718 bits (1853), Expect = 0.0
Identities = 505/1883 (26%), Positives = 885/1883 (46%), Gaps = 234/1883 (12%)
Query: 2797 RILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKA 2856
R+L N +G+ G GK++ + LA Y++ ++++ + + K +I A
Sbjct: 2653 RLLSRELENCFQIGIDGCGKKTCATLACYLTDNKLYRVPISHKCAYIEFKEVFKKVFIHA 2712
Query: 2857 AVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMN 2916
+K P+V ++ + + ++ FL +N +++SG IP LF E+++I +R + G
Sbjct: 2713 GLKGKPTVLMVPNLNIEQDSFLEDLNYIISSGRIPDLFENVELDSIAMKIRYLTEQSGHM 2772
Query: 2917 DTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVS 2976
D R++ FF +++ + L + + SP G R R +P++++ IDW+ WPE+AL+
Sbjct: 2773 DNRQSLLSFFQKRIYKNLHIFVIMSPEGPSFRQNCRVYPSMISSCTIDWYERWPEEALLI 2832
Query: 2977 VSARFLEET---EGIPVIKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIK 3033
V+ FL+E E +K ++ +H ++ +++R Y R+ YTTP ++L+ ++
Sbjct: 2833 VANSFLKEKVNFENRENLKEKLAPTCVQIHKSMKDLNRKYFEETGRFYYTTPNSYLQFME 2892
Query: 3034 LYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQ 3093
+ ++L + E+ K +R GL + + V +++ +L I +++QK + + L++
Sbjct: 2893 TFAHILRAREEEMQTKRDRFHMGLSTILEATTLVTEMQEELLILGPQVEQKTKETETLME 2952
Query: 3094 VVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNK 3153
+ +++ V K + + Q+E V + V + + +L PA A AL+ L+K
Sbjct: 2953 KLRKDSQVVEKVQMLVKQDEEIVAEEVRIVEDYAQKTANELKSVLPAFDKAIVALNALDK 3012
Query: 3154 NNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFD 3213
++ EL+ + PP V+ V AV IL + K +W AK+++ + FL L D
Sbjct: 3013 ADVAELRVYTRPPFLVLTVMNAVCIL------LQKKPNWATAKLLLSETG-FLKKLINLD 3065
Query: 3214 KEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQAL 3273
K+ IP+ K P F+P I S A LC W I + ++EV V PK+ +
Sbjct: 3066 KDSIPDKVFVKLKKIVTLPDFNPHKISLVSVACCSLCQWVIALNNYHEVQKVVGPKQIQV 3125
Query: 3274 EEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLAN 3333
EA L A+++L+ + + + +L L +A++ AEK +R A+
Sbjct: 3126 AEAQNVLKIARQRLAEKQRGLQLVEEHLLFLQAAYKDTVAEKQLLANRKTMASRRFQCAS 3185
Query: 3334 RLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPY 3393
L+ L E RW E++ ++ + GD+LL +A + Y G T ++R ++ K+
Sbjct: 3186 VLLTVLEDEKTRWQETINQIDNKLEGILGDILLSAACIVYSGILTPEFRQLIVNKWETFC 3245
Query: 3394 IHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQ 3453
I N I +++ + ++ +++ W+NQGLP + S ENA ++ N ++WPL++D
Sbjct: 3246 IEN---GISLSSKFSLIKVMAQKYEISRWHNQGLPHGQYSVENAILIKNGQQWPLLIDPH 3302
Query: 3454 LQGIKWIKNKYRSELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNT 3513
Q KWI+ S L+ + + +Y IE A+ G ++L++N+ ET+ P L +L ++
Sbjct: 3303 RQAHKWIRQMEGSRLQKLSIEDSNYTKKIENAMKTGGSVLLQNLLETLAPGLKAILKKDI 3362
Query: 3514 I-KKGKY-IKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLL 3571
KKG Y I++GD E EY+ FRL L T+ NPH+ P + T+INF VT GL+DQLL
Sbjct: 3363 YQKKGHYFIRVGDAEFEYNSNFRLYLSTEIDNPHFLPSVYNFVTMINFTVTFQGLQDQLL 3422
Query: 3572 AAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETT 3631
+ VV E P LE ++ L +S + I L+ELE+ L L A G+ L D +V+ L +
Sbjct: 3423 STVVTHEVPHLEDQRSKLLESISLDAITLEELEEKTLNLLQKALGSILDDDKIVDTLRKS 3482
Query: 3632 KHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFN 3691
K T++EI +++ K E +I R+NY P A R +LLYF++ DL +IN +YQFSL F+
Sbjct: 3483 KMTSNEISKRIEATKKAESEIQAIRKNYLPIATRGALLYFLVADLTQINYMYQFSLDWFH 3542
Query: 3692 VVFEKAI-------------QRTTP------------------ANEVKQRVINLTDEITY 3720
VF ++ ++ +P N + + + + D +T
Sbjct: 3543 QVFVSSVVSKSKEQEHSFKREKVSPKEVHEFISISKEPNLENEKNLLDKHIKSAIDMLTK 3602
Query: 3721 SVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELD--FL----------------- 3761
S++ + LF DKL F ++ ++ N ++ D FL
Sbjct: 3603 SIFKVVSSALFNEDKLCFSFRLCTVIMQNNANGNLIQDDIGFLPEEEWNIFLYSGILINI 3662
Query: 3762 --------LRFPFKAGVVSPVDFLQHQGWGGIKALS-EMDEFKNLDSDIEGSAKRWKKLV 3812
L F+ G + +L W + +S ++ F L + + +W
Sbjct: 3663 KSALSQSRLTSTFEIGESQHLQWLSDSRWRQCQYVSTHLEPFSLLCKSLLSNVSQWDTFK 3722
Query: 3813 ESEAP---------------EKEIFPKE------------------WKNKTALQKLCMVR 3839
S+A E+ P E W+ T+ Q+L +V+
Sbjct: 3723 NSKAVYSLISTPFSSENASLEENTKPPEETELLNENKETCNPINFPWEKLTSFQRLILVK 3782
Query: 3840 CLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEA 3899
LRP+ + +++ F+ EKMG+K+++ V +Y+ S+ T + I + G+D +
Sbjct: 3783 VLRPESLNNSVRKFITEKMGNKYLQRTGVNLKDAYKGSNARTPLILIQTHGIDLTNILLR 3842
Query: 3900 LGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEK-GHWVILQNIHLVARWLGTLDKK 3958
++L T + + +SLG+ Q AE+ + A K WV LQN HL ++ L
Sbjct: 3843 FAQELKGTTHHVTI--ISLGRDQAAKAEDLILKALTKTQQWVFLQNCHLATSFMPRLCTI 3900
Query: 3959 LERYSTGS---HEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALD 4015
+E +++ + ++R+++S++ S P +L+ +KI E P G+ +NL +
Sbjct: 3901 VESFNSPNVTIDPEFRLWLSSKSYSS-----FPIPVLKKGLKIAVESPQGLKSNLLQTFG 3955
Query: 4016 L-----FTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTIS 4070
T++ E +K +LF+LC+F+AV+ ER+ +G GWN +Y FN+ DL ++
Sbjct: 3956 CTGSGEVTEEIFENPDCGQWWKKLLFSLCFFNAVINERKNYGILGWNIAYKFNSSDLGVA 4015
Query: 4071 INVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLL 4130
I VL N L P + W LRYL GE++YGG + D+WD+R +T L ++ E+L+ D
Sbjct: 4016 IKVLENSLRGQPSISWQALRYLIGEVIYGGRVIDNWDKRCLKTLLYKFCNPEVLKDD--- 4072
Query: 4131 APGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKE 4190
F + K Y I + P + G+HP A EK ++ MQPK
Sbjct: 4073 ---FSFSRSASIKDYIHIIQSLPDDDLPEVLGIHPEAIRSCWETQGEKFIENLIAMQPKT 4129
Query: 4191 TDSG--AGTGVSREEKVKAVLDDILEKIPETFNMAEIMA--------------------K 4228
T + S++E V +L D+L+++P T EI
Sbjct: 4130 TTANLMIRPEQSKDELVMEILSDLLKRLPLTVEKEEIAVGTPSTLKSMMSSSIWESLSKN 4189
Query: 4229 AAEKTPY---VVVAF--QECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFY 4283
+ P V++ F QE +R + L + +SLK+L L +KGE+ +T ++E++ +
Sbjct: 4190 LKDHDPLIHCVLLTFLKQEIKRFDKLLFVIHKSLKDLQLAIKGEIILTQELEEIFNSFLN 4249
Query: 4284 DTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWT------------------------ 4319
VP W AY S L++W DL+ R+ W
Sbjct: 4250 MRVPTLWQKHAYRSCKPLSSWIDDLIQRLNFFNTWAKVAYTAIQRRYMRFVTVWKQSIPS 4309
Query: 4320 ------------TDF--ALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEV- 4364
+F P+ WL FF PQ+FL A++Q R +D + + V
Sbjct: 4310 TSQKCKHPEDSENNFFEGFPSRYWLPAFFFPQAFLAAVLQDYGRSRGIAVDALTFTHHVI 4369
Query: 4365 ---TKKNREDMTAPPRE----------------GSYVYGLFMEGARWDTQTGVIAEARLK 4405
T K+ + P++ G Y++GLF+EGARW+ + ++ ++
Sbjct: 4370 SNTTDKDEKFSVFMPKKLNIVRRAFKGSASSHTGVYIFGLFIEGARWNREQKILEDSLPL 4429
Query: 4406 ELTPAMPVIFIKAIPVDRMETKN----------IYECPVYKTRIRG--------PT-YVW 4446
E+ P I+ + +T N +ECPVY+T R PT ++
Sbjct: 4430 EMCCDFPDIYFLPTKIS-TKTPNASNQTDSELYAFECPVYQTPERSRILATTGLPTNFLT 4488
Query: 4447 TFNLKTKEKAAKWILAAVALLLQ 4469
+ L TK+ + WI VALL +
Sbjct: 4489 SVYLSTKKPPSHWITMRVALLCE 4511
Score = 622 bits (1604), Expect = e-177
Identities = 420/1390 (30%), Positives = 679/1390 (48%), Gaps = 223/1390 (16%)
Query: 1284 EVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFV 1343
++ L K+LW+ + +W+ + + I+VE + + K + L+K + D
Sbjct: 995 DLTLRKKLWEAQEEWKRASWEWRNSSLQSIDVESVQRNVSKLMHIISVLEKGLPKSDMVT 1054
Query: 1344 GLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLADLLQLNLHSYE 1403
L V L + L NP ++ RHW+ L + + + + +LL L + YE
Sbjct: 1055 HLKQVVTEFKQELPIIIALGNPCLKPRHWEALQEIIGKSVPLDKNCKVENLLALKMFQYE 1114
Query: 1404 DEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRT--GTMMLKSSEVLVETLEDN 1461
+E+ ++ A E+ +EK+L + W+ H ++ S + + LE++
Sbjct: 1115 NEINDMSTSATNEAALEKMLFKIIDFWNTTPLPLILHHTEIYSIFIIPSIDDISAQLEES 1174
Query: 1462 QVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQ 1521
QV L + S ++ V W Q L+ + W QR W +LE +F SE IR Q
Sbjct: 1175 QVILATIKGSPHIGPIKDLVNEWDQNLTLFSYTLEEWMNCQRNWLYLEPVFHSSE-IRRQ 1233
Query: 1522 LPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEYLE 1581
LP +++ F + +K +M N ++ T+ G+ L+ L +K+L +YLE
Sbjct: 1234 LPAETELFSQVISMWKKIMSKIQNKQNALQITTSAGVLEILQNCNIHLEHIKKSLEDYLE 1293
Query: 1582 TKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLK-FRLDASDKPLKVGL 1640
KRL FPRFYF+S+A+LLDIL++ +P V HL K F+++ +L ++ D +K+
Sbjct: 1294 VKRLIFPRFYFLSNAELLDILADSRNPESVQPHLVKCFENIKQLLIWKQDIGPPAVKM-- 1351
Query: 1641 GMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPREQWILDY 1700
+ S E E +V ++ + VE WL V M L+ +E++I +
Sbjct: 1352 -LISAEGEGLVLPKKIRVRSAVEQWLVNVEKSMFDVLK--------------KERYIYNI 1396
Query: 1701 PAQVALTCTQIWWTTEVGLAFARLEEGYENAIRDYNKKQISQLN---------VLITLLM 1751
+ L +QI + + +F + Y+++++ +++ V +++
Sbjct: 1397 ---ILLFQSQIMFYNDCVKSF----------VSSYSREKLEKVHAGLMCHLEEVADLVVL 1443
Query: 1752 GNLNAGDRMKIMTICTIDVHARDVVAKMIVAKVESSQAFTWQAQLRHRWDEEKRHCFANI 1811
N+ + + + + VH RD+V +++ + +++ F W L+++W+E+++ C+ +
Sbjct: 1444 DTSNSRTKAILGALLILYVHCRDIVINLLLKNIFNAEDFEWTRHLQYKWNEKQKLCYVSQ 1503
Query: 1812 CDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGR 1871
+A Y YEYLG T RLVITPLTDRC++TL ++LHL +GG PAGPAGTGKTET KDL +
Sbjct: 1504 GNASFTYGYEYLGCTSRLVITPLTDRCWLTLMEALHLNLGGCPAGPAGTGKTETVKDLAK 1563
Query: 1872 ALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDA 1931
+LG VFNC E +DYK + GL Q+GAW CFDEFN I +EVLSVIA Q+ ++ A
Sbjct: 1564 SLGKHCVVFNCFEDLDYKIVRKFFFGLVQSGAWSCFDEFNLIDLEVLSVIASQILTIKAA 1623
Query: 1932 IRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICE 1991
F G+ I + + +FITMNP Y G ELP+NLK+LFRP AM+VP +++I E
Sbjct: 1624 KDNYSARFVLEGKEIRINMSCAVFITMNPRYGGGVELPDNLKSLFRPVAMMVPHYQMIAE 1683
Query: 1992 IMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRA 2051
I+L + GF A L+ K LY L ++ LS+QDHY++GLR++K VL++AG+ KR +
Sbjct: 1684 IILFSFGFKSANSLSGKLTNLYELARKQLSQQDHYNFGLRSLKIVLIMAGTKKREFKCLS 1743
Query: 2052 EDQ---VLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVEL 2108
E +++ A+R+ ++PK +D+P+F +IGD+FP + V + L EK+I + +L
Sbjct: 1744 EADETLIVIEAIREASLPKCPPEDVPLFENIIGDIFPEVTVLKVNQLALEKVIYTATQQL 1803
Query: 2109 KLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNL---------KR 2159
LQ S K++Q LQV V +VG G GK+ V + L K L +R
Sbjct: 1804 GLQNWSSQKEKIIQFYNQLQVCVGVMLVGPTGGGKTTVRRILEKALTLLPIADFLSVAER 1863
Query: 2160 KPVA--------VD---LDPKAVTCDELFGIINPVTREWKDGLFSTIMR----------- 2197
K + VD L+PK VT EL+G ++P T EW DGL S +R
Sbjct: 1864 KSASKISERKGKVDICVLNPKCVTLSELYGQLDPNTMEWTDGLLSATIRSYVYFNTPKNT 1923
Query: 2198 -------------DLANI----------THDGP------------------KWIILDGDI 2216
DL+N+ T D +WIILDG +
Sbjct: 1924 KKDIDLRLKSRISDLSNVFKLDSSDTTETDDNIFEEIEKVVKIPENHNFDWQWIILDGPV 1983
Query: 2217 DPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPA 2276
D W+E+LN+V+DD + L LA++ERI L +R++FE+ +L A+PATVSR ++Y++P
Sbjct: 1984 DTFWVENLNSVLDDTRTLCLANSERIALTNKIRVIFEVDNLSQASPATVSRCAMVYMDPV 2043
Query: 2277 DLGWNPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRF--GFKKITPVP--EITVIQ 2332
DLGW P V SW+ + ++ + L + D L+F +K P P +ITV+
Sbjct: 2044 DLGWEPYVKSWLLKTSKIISQSGVDCLEFMIKNSVTDGLQFIRNRQKFQPYPMEDITVVI 2103
Query: 2333 TILYLLECL------------------------------LTEKTVP------------PD 2350
T+ +L+ +T K + PD
Sbjct: 2104 TLCRILDAFFDFMGKNGGFEQSDDLNDTSSKEANSQRESVTFKDIEKRDENTWYPEKNPD 2163
Query: 2351 SPRELYELYFVFTCFWAFGGAMFQ----------------DQLVDYRVEFSK-------- 2386
++ + FVF WAFGGA+ + D L +F K
Sbjct: 2164 KLTKIIQKLFVFAFTWAFGGALNREDEHRENIPFCPSLEPDSLAKVTYDFDKLVHELFGN 2223
Query: 2387 --------WWINEFK-----TIKFPS-QGTIFDYYIDPDTKKFLPWTDKVPSFE--LDPD 2430
W ++ + I P+ + +IF Y++D + +F+PW+D VP+ + +
Sbjct: 2224 SSQVGWKHWGQSQGRRRKGNCINLPTGECSIFGYFVDIEQCEFIPWSDLVPNDQTLIQRG 2283
Query: 2431 VPLQASL-------------------VHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKS 2471
L +L T +T + + M LL++ S PV+L G +G GK+
Sbjct: 2284 TSLLTNLQRSGGNFLKITECGECINYTATRDTTCLSFLMSLLLKNSCPVLLTGESGVGKT 2343
Query: 2472 VLMGDKLESL 2481
+ LE L
Sbjct: 2344 AAINQMLEKL 2353
Score = 134 bits (336), Expect = 3e-30
Identities = 74/240 (30%), Positives = 125/240 (52%), Gaps = 2/240 (0%)
Query: 2487 LVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGTVAP 2546
+V + F+ T+A + ++ K L +++ G P +++ FIDDMNMP D YG P
Sbjct: 2426 VVSTINFSTNVTAAKTKEMILKKLIRRTKDTLGAPKNNRILIFIDDMNMPVSDMYGAQPP 2485
Query: 2547 HTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGSFTIDSRLQRHFCVFAVSFPGQ 2606
LIRQ +D YD K T K+I + VA P I RL +HF + + P Q
Sbjct: 2486 LELIRQLLDLGGVYDTEKNTWKNIQDLSIVAACVPVVND--ISPRLLKHFSMLVLPHPSQ 2543
Query: 2607 EALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYVFNLR 2666
+ L TI+ L + + + + +Q+ Q+++ +LA++ ++ LPT K HY+FNLR
Sbjct: 2544 DILCTIFQAHLGIYFSINNFTPEVQKSKDQIISCSLAIYHQVRQNMLPTPTKCHYMFNLR 2603
Query: 2667 DLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTKKFF 2726
D+ + GLL + V+ + L++HE RV+ D+++D D+ +R+ + F
Sbjct: 2604 DMFKLLLGLLQADRTVVNSKEMAALLFVHEATRVFHDRLIDFTDKSLFYRLLSRELENCF 2663
>gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]
Length = 4753
Score = 176 bits (445), Expect = 6e-43
Identities = 332/1715 (19%), Positives = 639/1715 (37%), Gaps = 293/1715 (17%)
Query: 1269 EVPVPDYKQLKACH-REVRLLKELWDMVVVVNTSIEDWKTTKWKDINV----EQMDIDCK 1323
E PVP L C R + + +W + V++ +I +WK + + E+ +
Sbjct: 1002 ETPVP----LPICGTRPIVQQQRIWHLYRVISENISEWKCMAFAKFSPAMAQEKTEGWLT 1057
Query: 1324 KFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQV-K 1382
+ A+ +L+ + + ++ + L + L ++ + Q L++A +
Sbjct: 1058 EAARMSTTLELHSPVLQHCMRILGEFRSYLPLLTKLGSLHPQSL---NCQCLLRALGLGS 1114
Query: 1383 FKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQ------ 1436
+ E TL LL L + D + + + ++ ++ L W + +
Sbjct: 1115 LQTIELLTLGQLLTYPLLEFADRINQVWQNENERIHAQETIRRLQRYWEARQLRLLNFIL 1174
Query: 1437 HEPHPR----------------------TGTMMLKSSEVLVETLEDNQVQLQNLMMSKYL 1474
H P+ +GT +L L ++++++ L ++ +
Sbjct: 1175 HVPYEPPASERSKRQVLRSPQWEVVDKDSGTFILSDYSNLQDSIQESLQVLSKILAIEKS 1234
Query: 1475 AHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGD--SQRFDDI 1532
K W + +++ +W Q+ W L + +++ Q P + RF +
Sbjct: 1235 GDLNKIALEWVAIMHGLGALLEVWLTFQQKWIFLNKVL---HEMKIQFPNADLNSRFKVM 1291
Query: 1533 NQEFKALMEDAVKTPNVVE-----ATSKP-----GLYNKLEALKKSLAICEKALAEYLET 1582
+ +++ LM +V P V+ A P L L+A L +L L
Sbjct: 1292 DDQYRTLMRISVADPMVLSLVVPSAERSPYFQGQQLQQLLQAGSVELEGIIMSLESVLYG 1351
Query: 1583 KRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFR-------------- 1628
FPR +F+S ++L+ +L+ + E + + F + + FR
Sbjct: 1352 VCAHFPRLFFLSDSELVALLAARLESCEAQLWVRRCFPHVHAVSFRSCPTGEKNTDDWES 1411
Query: 1629 -------------LDASDKPLKVG--LGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRM 1673
L A + +K+ L ++ +++ ++C V + V R+
Sbjct: 1412 SPNTQTQVEALAVLGAGGEEVKLQGPLPLHPDLPKWLASLEKCLRLALVHMLQGCVAARL 1471
Query: 1674 C-----STLRHEIPEAVVTYEEKPREQWI---LDYPAQVALTCTQIWWTTEVGLAFARLE 1725
++P+ Y + + WI +P Q L ++ W E+ A LE
Sbjct: 1472 ARGPSLGEALKQLPKQNKLYLQLYVQHWIDLVQAFPWQCVLVAEEVVWRAEMEEAL--LE 1529
Query: 1726 EGYENAIRDYNKKQISQLNVLITLLMGNLNAGDRMKIMTI---------CTIDVHARDVV 1776
G + + +K L VL+ + + + ++ + V RD+
Sbjct: 1530 WGTLAMVSMHMRK----LEVLVNFMRAQRASQGGQSLPSVRQTSLLSALLVMAVTHRDIA 1585
Query: 1777 AKMIVAKVESSQAFTWQAQLRHRWDE----------------------EKRHCFANICDA 1814
+ +V F W QL++ C+ ++
Sbjct: 1586 QLLEQHQVSDLTDFHWVRQLKYHLGSPHIIPKSPLQSLKTIASSEPSLSPAACWIDVLGR 1645
Query: 1815 QIQYSYEYLGNTPRLVITP--LTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRA 1872
Y+YEYLG PRL P L +R + L +L + G GP G GK L +A
Sbjct: 1646 SFLYNYEYLG--PRLGPLPSLLPERPALVLLLALEEVACGTVLGPNGVGKRAIVNSLAQA 1703
Query: 1873 LGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQV------- 1925
LG + + CS Q++ + N G Q GAW ++ +++ +LS + ++
Sbjct: 1704 LGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLLLEKVHQLPPGLLSALGQRLGELHHLY 1763
Query: 1926 -KCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGY-------AGRAELPENLKALFR 1977
Q+A R +++G +++ GY A + +P NL L R
Sbjct: 1764 APLYQEASRNTSTIDPTQPQLLGSSFFEKHHVSVRLGYGCLLVLRALSSAVPANLHLLLR 1823
Query: 1978 PCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLS----------KQDHYD 2027
P A+ +PD + E+ L+ G +A +A + ++L +EL+S KQ D
Sbjct: 1824 PVALALPDLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGPLPCRLPLLKQILED 1883
Query: 2028 WGLRAIKSVLVVAGSLKRGDP---SRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLF 2084
I+++ V K P + E+ L+R+ + + +L GL+ LF
Sbjct: 1884 ----TIRTLNVTKEEPKCQKPRSLAAIEEAALLRSPLFSILNGLHLHNL---RGLLCALF 1936
Query: 2085 PALDVPRKRDLNFEKIIKQSIVE----LKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAG 2140
P+ + + K++K +VE + L + + QL + L + ++G AG
Sbjct: 1937 PSASQVLAEPMTY-KLMKPLVVEELQQVGLDPSPDILGSLEQLSQALSRASGILLLGPAG 1995
Query: 2141 SGKSQVLKSLNKTYQNLKR---------KPVAVD-LDPKAVTCDELFGIINPVTREWKDG 2190
SGK+ SL K L +PV + L P ++ E G + W G
Sbjct: 1996 SGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITHLYPSGLSPQEFLGWLEGSC--WHHG 2053
Query: 2191 LFSTIMRDLANITHDGPK-----------WIILDGDIDPMWIESLNTVMDDNKVLTLASN 2239
+F ++R + G K WII DG + W++S+ ++ + L+L S
Sbjct: 2054 IFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICDGASNGAWLDSITCLLSELPQLSLPSG 2113
Query: 2240 ERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWI-----ERRKVQ 2294
++I L+ E++ +P V +++ + W ++S+ + E R
Sbjct: 2114 QQIARPPGTFLLMEVADTTGISPTVVGCCALVWCG-GEQTWQCILSALMASLPYEYRLQH 2172
Query: 2295 SEKANLMILFDKYLPTCLDKLRF-GFKKI----------TPVPEITVIQTILYLLECL-- 2341
A L + + +P L L G + V E+T + IL+ L L
Sbjct: 2173 RTVAELNHMAEVLVPATLRFLTCQGVSSLLQVHGQQAVCAGVAEVTSMARILHSLLDLHL 2232
Query: 2342 -LTEKTVP---------------------------------PDSPRE--LYELYFVFTCF 2365
L E+ P PD RE L F+F
Sbjct: 2233 RLKEEKAPGPEDLSYSDPVAQSFRSSKSSFLNRSQVDSDDVPDKCREHLLAVSSFLFALI 2292
Query: 2366 WAFGGAMFQD--QLVDYRVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKKFLPWTDKVP 2423
W FG + + D + S ++ + + P +FD ++ P+ +P+T +
Sbjct: 2293 WGFGAHLPSRFWPIFDTFIRDSISRLSNYP--EPPPSALVFDLHVSPEDGTLVPFTGQYL 2350
Query: 2424 SFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNT 2483
S + + + + +T R+ Y +DLL+ PV+L G A TGKS + +E +
Sbjct: 2351 SSHIKGTL---GTFHPSIQTERLLYVVDLLLSGGQPVLLAGEAATGKSAFVEVLVEPHHP 2407
Query: 2484 DNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGT 2543
Y F+ +L ++ + + L++ ++D+++ D +
Sbjct: 2408 YIYSPIHPAFSSSHLRLLLSRGIQGQTQASPQPGHHQDSKPSLLFLLEDLHLATSDPEKS 2467
Query: 2544 VAP-HTLIRQHMDHRHWYDRHKLTLKDIH-NCQYVACMN-PTSGSFTIDSRLQRHFCVFA 2600
P +RQ MD Y L L+ + ++A + P + RL R F V A
Sbjct: 2468 CQPVLETLRQAMDGT-VYAHSTLELQTLQPTVNFLATVTVPGYCERPLCPRLFRLFTVLA 2526
Query: 2601 VSFPGQEALTTIYNTILTQHL-AFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKF 2659
+ Q L + I+ L F SV + ++ LV A++ + + F+P+ +
Sbjct: 2527 LESMTQATLLERHVPIIQAWLERFPSVERE-RALARGLVRASVEAWEAVCNCFMPSPLHP 2585
Query: 2660 HYVFNLRDLSNIF----------------------------QGLLFSTAEVLKTPLDLVR 2691
HY F+L +S++ GL + V+ ++VR
Sbjct: 2586 HYHFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTCLTVMMATRNVVR 2645
Query: 2692 LWLHETERVYGDKMVDEKDQETLHRVTMASTKKFF 2726
LWLHE +R + D++ +++ ++ + + F
Sbjct: 2646 LWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVF 2680
Score = 122 bits (307), Expect = 6e-27
Identities = 158/722 (21%), Positives = 293/722 (40%), Gaps = 78/722 (10%)
Query: 2791 HICRINRILESPRGNALLV-GVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDL 2849
H+ R+ R+L PR + LL+ G G+G+ + LA+ I F + I D
Sbjct: 2871 HVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPSGSEEAILQCLRDA 2930
Query: 2850 AAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLA---SGEIPGLFMEDEVENIISSM 2906
+ A + + P V L+ S V L ++ LLA SG PG + E +++ I +
Sbjct: 2931 SWH---AGMLSQP-VALLVPSGVD----LTTLHRLLALATSGSFPGQYTEADLDRIGEHL 2982
Query: 2907 RPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCT--AID 2964
+ + N +E + F ++V L + + ++ + F ++ +ID
Sbjct: 2983 PRENLGVKQNIKKEMVLQRFHQQVCSHLHLFFLIGDKQAHKQLPSTLFLRLLQLATASID 3042
Query: 2965 WFHEWPEDALVSVSARFLEETEGIPVIKASISF--FMSYVHTTVNEMSRVYLATERRYNY 3022
+ W + AL V+ LE + +P+ S + + + + M+ ++L+ + +
Sbjct: 3043 RYEPWDQAALAKVAQHHLEGAQSVPLDDGSWKYPDLQASIPSVAKAMALIHLSATHYHEH 3102
Query: 3023 -------TTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLA 3075
TPKTFL+ + + L + ++ K +R++N L L+ + +
Sbjct: 3103 LCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRMLIKEHGTHANLIF 3162
Query: 3076 IQEAELKQKNESADQLIQVVGIEAEKVSKEKAIAD--QEEVKVEVINKNVTEKQKACETD 3133
E +LK +S Q +E K+ ++ + + +E +E + + Q E
Sbjct: 3163 DLEQQLKDSGKSLSMFQQQ--LEQSKLLYKQQLEECRHQENLIENLARQRDALQAQREAF 3220
Query: 3134 LAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWK 3193
L + A L E L L + E++S+ +PP++VV VT A+ L + W
Sbjct: 3221 LEQMSKAFL---EPLSQLQVADFEEIRSYRAPPESVVRVTDAMCDL------FHHETGWA 3271
Query: 3194 AAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWC 3253
+AK ++ D F L F KE I ++ L P D +R+ S AA L +W
Sbjct: 3272 SAKQLLCTED-FYQELVFFPKEKITDSELIKLHLILKAPGMDDAALRAVSRPAASLAAWL 3330
Query: 3254 INIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATA 3313
++ + +C P L++ A L Q +L + + E + L E A A
Sbjct: 3331 WAVLHYGLAHCRGLPTDLLLQQVEATLTREQARLGYYQFQAQETLEHNLALAKMVEDAQA 3390
Query: 3314 E-----KIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLIS 3368
K Q + ++ + A L + W ++ + + +T+ GD LL S
Sbjct: 3391 SHNCVAKTLSQAQCGQYHKWPMKA-----ALLTPMRAWTTQLQKLKGRCMTVFGDTLLCS 3445
Query: 3369 AFVSYVGYFTKKYRNELMEKFWIPYIHNLK------------------VPIPITNGL--- 3407
A + Y+G F R EL+++ W+ + V IP N L
Sbjct: 3446 AAIIYLGPFPPLRRQELLDE-WLALCRGFQEALGPDDVAQALKRKQKSVSIPPKNPLLAT 3504
Query: 3408 ----DPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTE-----RWPLIVDAQLQGIK 3458
LSLL+ +++ W+ P + + +L + RWPL++D + +
Sbjct: 3505 HSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPLLLDPSNEALI 3564
Query: 3459 WI 3460
W+
Sbjct: 3565 WL 3566
Score = 72.4 bits (176), Expect = 9e-12
Identities = 192/975 (19%), Positives = 346/975 (35%), Gaps = 126/975 (12%)
Query: 3566 LEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALV 3625
LE+Q+L ++ +E P+LE +L + ++ E+ LL L + +
Sbjct: 3757 LEEQMLHEILCREYPELETRWQDLKIRALDTCKAVEAAEERLLTMLLFQNPKRQKPAKFL 3816
Query: 3626 ENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQF 3685
N+ + ++ E + +++ YRP + L+ L + P++
Sbjct: 3817 RNIVRAQGKLCQLRAHCEELEGQKLQEMVLWAPYRPVVWHGMAMVKALSQLQNLLPLFCM 3876
Query: 3686 SLKAFNVVFEKAIQRTTP---------ANEVKQRVINLTDEITYSVYMYTARGLFERDKL 3736
S + + V ++A+ P A+ + Q +LT ++ S TA GL + +
Sbjct: 3877 SPENWLAVTKQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTV--TALGLTQVPLV 3934
Query: 3737 IFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVS-----PVDFLQHQGWGGIKALSEM 3791
L + + K EL+ L +P A S PV + W G KA E
Sbjct: 3935 GALGALALLQATGKAS----ELERLALWPGLAASPSTVHSKPVSDVARPAWLGPKAWHEC 3990
Query: 3792 D------EFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTAL-QKLCMVRCLRPD 3844
+ F L + + G + W+ + + P +L QKL + R LRP+
Sbjct: 3991 EMLELLPPFVGLCASLAGHSSAWQAYLSLSSTVLGPAPGPGPEPLSLLQKLILWRVLRPE 4050
Query: 3845 RMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALG--K 3902
+ A+ +F +G E + ++ S + + +L P P + L +
Sbjct: 4051 CLAGALADFTTSLLGRPLDENTYAP-TMPFKHSQATQPMLILLPPPGHPSATLHPLTVIQ 4109
Query: 3903 KLGFTIDNGKLHNVSLGQGQEV-----VAENALDVAAEKGHWVILQNIHLVARW------ 3951
KL G+ + G E V + L A +GHW++L N HL+ W
Sbjct: 4110 KLAAKYQQGQKQLQVIALGSEAWDPVSVVVSTLSQAMYEGHWLVLDNCHLMPHWPKELLQ 4169
Query: 3952 -----LG------------TLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILEN 3994
LG LD+ R + H D+R+++ P+ + +P
Sbjct: 4170 LLLELLGRAKVVADLESEQLLDQPESRNVSTVHRDFRLWLI---VPAESSASLP------ 4220
Query: 3995 AIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQ 4054
A+ + P + +L L L M+ L H ++ R+ +G +
Sbjct: 4221 AVLTQHSMPVFWNQSLELGHVLIDSVELAQQVLYMQPPTQALPLLLLHGLLLHRQLYGTR 4280
Query: 4055 GWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRR----L 4110
++ LT + + L A+ P ++ L + YGG + D DR L
Sbjct: 4281 LQAHRGRWSQVTLT-QVLQTQDQLWASLSNPRAAMQELAASVFYGGPLGDTEDREALISL 4339
Query: 4111 CRTYLA----EYIRTEMLEGDVLLAPGFQIPP--NLDYKGYHEYIDENLP-PESPYLYGL 4163
+ L+ +++ + LLA +P LD + LP P P L GL
Sbjct: 4340 TQACLSPSSGSWVQPHTPQS--LLATLMPLPELRELDAMAECKAQMHLLPSPPEPRLCGL 4397
Query: 4164 HPNAEIGFLTVTSEKLFRTVLEMQP---KETDSGAGTGVSREEKVKAVLDDILEKIPETF 4220
+ L S L + P E+ GA R + ++ LE + +
Sbjct: 4398 SEGPQAWLLRRQSRALLSALQRSSPVWVPESRRGAQLAERRLRQRLVQVNRRLESLQDL- 4456
Query: 4221 NMAEIMAKAAEKTPYVV-----------VAFQECERMNILTNEMRRSLKELNLGLKGELT 4269
+ ++ + P+ V V E ++ L ++R L L LKG
Sbjct: 4457 -LTHVIRQDESDAPWSVLGPNARRPLEGVLETEALELSQLVGTLQRDLDCLLQQLKGAPP 4515
Query: 4270 I-TTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWY------ADLLLRIRELEAWTTDF 4322
+ ++ AL+ +P W A W LL+R + A +
Sbjct: 4516 CPSRRCAAVAHALWTGRLPLPWRPHAPAGPQPPWHWLRQLSRRGQLLVRYLGVGADASSD 4575
Query: 4323 ALPTTVWLAGFFNPQSFLTAI-----MQSMARKNEWPLDKMCLSVEVTKKNREDMTAP-- 4375
L+ F +P+ L A+ + + +P + +S ++ K E + P
Sbjct: 4576 VPERVFHLSAFRHPRRLLLALRGEAALDQNVPSSNFPGSRGSVSSQLQYKRLEMNSNPLH 4635
Query: 4376 -----------PREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIP---- 4420
P G + GL + A WD G + ++ + +P PV P
Sbjct: 4636 FRVENGPNPTVPERGLLLIGLQVLHAEWDPIAGALQDSPSSQPSPLPPVSISTQAPGTSD 4695
Query: 4421 VDRMETKNIYECPVY 4435
+ +Y CPVY
Sbjct: 4696 LPAPADLTVYSCPVY 4710
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 47.8 bits (112), Expect = 2e-04
Identities = 99/485 (20%), Positives = 189/485 (38%), Gaps = 86/485 (17%)
Query: 3258 RFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAE---LNANLSNLTSAFEKATAE 3314
R EV + K Q L+E +L QE++S ++ KI E L L N E E
Sbjct: 1121 RLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETE 1180
Query: 3315 KIKCQQ-------EADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLI 3367
+++ Q E + + + L +E + + G+ ++ +
Sbjct: 1181 RLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIA 1240
Query: 3368 SAFVSYVGYFTKKYRNELMEKFW-------IPYIHN-LKVPIPITNGLDPLSLLTDDADV 3419
+ + R + EK + H L+ IP+ + + LL + +V
Sbjct: 1241 HIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLH--EEQELLPNVKEV 1298
Query: 3420 A----TWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQ 3475
+ T N L +++ +T+++T L E L ++ + Q + + E+K++ +
Sbjct: 1299 SETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQ-------ESQEEIKSLTK-E 1350
Query: 3476 KSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRL 3535
+ L I++A+ L E+I ET+ + + + K+ + + + +K+ E ++
Sbjct: 1351 RDNLKTIKEALEVKHDQLKEHIRETLAKIQE-----SQSKQEQSLNMKEKDNE---TTKI 1402
Query: 3536 ILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNE 3595
+ + F P ++ + ++ D++ + VAKE+ DL++L+ L ++
Sbjct: 1403 VSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKS--VAKEKDDLQRLQEVLQSESDQ 1460
Query: 3596 FKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEA--KITEVKIN 3653
K +KE+ KH +E E KV K E IN
Sbjct: 1461 LKENIKEI--------------------------VAKHLETEEELKVAHCCLKEQEETIN 1494
Query: 3654 EARENYRPAAERASLLYFILNDL-----NKINPVY----QFSLKAFNVVFEKAIQRTTPA 3704
E R N S + L + NKI +Y QF++K + V EK
Sbjct: 1495 ELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEK-------V 1547
Query: 3705 NEVKQ 3709
NE+KQ
Sbjct: 1548 NELKQ 1552
Score = 47.0 bits (110), Expect = 4e-04
Identities = 194/1041 (18%), Positives = 397/1041 (38%), Gaps = 178/1041 (17%)
Query: 3039 LAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIE 3098
L++K TE+ ++LE KLQ+ ++ + + ++ +KQ +E +++ ++ +
Sbjct: 1500 LSEKETEISTIQKQLEAINDKLQNKIQEIYEKE-----EQFNIKQISEVQEKVNELKQFK 1554
Query: 3099 AEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEAL----DTLNKN 3154
+ +K+ A+ E +E+ N+ + E Q+ + + K + + QEAL D L +N
Sbjct: 1555 EHRKAKDSALQSIESKMLELTNR-LQESQEEIQI-MIKEKEEMKRVQEALQIERDQLKEN 1612
Query: 3155 N---LTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKK 3211
+ ++K + +TA + ++ K+ + ++T L +
Sbjct: 1613 TKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQ 1672
Query: 3212 FDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQ 3271
E++ E + T + + +RS +R E K++
Sbjct: 1673 ILHENLEE---------MRSVTKERDDLRSVEETLKVERDQLKENLR--ETITRDLEKQE 1721
Query: 3272 ALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKAT----AEKIKCQQEADATNR 3327
L+ + L E QE + +++ ++E +SN+ E + A+ +K Q+E +
Sbjct: 1722 ELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHM 1781
Query: 3328 VILLANRLVG---GLASE---------------NIRWAESVENFRS---QGVTLCGDVLL 3366
+ + G+ SE N + E ++ ++ Q +TL DV
Sbjct: 1782 HLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNE 1841
Query: 3367 ISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQG 3426
VS + K+ +++ + + I NL + + L+ + + + D +
Sbjct: 1842 TQKKVSEMEQLKKQIKDQSLTLSKLE-IENLNLAQKLHENLEEMKSVMKERDNLRRVEET 1900
Query: 3427 LPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKSY---LDVIE 3483
L +R + + LQ K + + ELK R+ K + +D +
Sbjct: 1901 LKLERDQLKES----------------LQETKARDLEIQQELKTARMLSKEHKETVDKLR 1944
Query: 3484 QAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTKYFN 3543
+ ISE T+ I +I + +D D L + + K +++ + + + + I +
Sbjct: 1945 EKISE-KTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLK 2003
Query: 3544 PHYKPE---MQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVL 3600
++ + MQ+ + NF +T+ E +VAKER +L ++K +L +++F L
Sbjct: 2004 KQFEAQNLSMQS-VRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATL 2062
Query: 3601 KELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYR 3660
+E ++AR + + L+ + +H + EK K + +E ++Y
Sbjct: 2063 RE----MIAR-DRQNHQVKPEKRLLS--DGQQHLTESLREKCSRIKELLKRYSEMDDHYE 2115
Query: 3661 PAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITY 3720
R SL DL K + F+K + AN + L +
Sbjct: 2116 -CLNRLSL------DLEK------------EIEFQKELSMRVKAN---LSLPYLQTKHIE 2153
Query: 3721 SVYMYTARGLFERDKLI-FLAQVTFQVLSMKKE----LNPVELDFLLRFPFKAGVVSPVD 3775
++ R E +++ L V V +K+E +N E+DF+ + ++ +
Sbjct: 2154 KLFTANQRCSMEFHRIMKKLKYVLSYVTKIKEEQHESINKFEMDFIDEVEKQKELLIKIQ 2213
Query: 3776 FLQHQGWGGIKALSEMDEFKNLDSDIE-----------GSAKRWKKLVESEAPEKEIFPK 3824
LQ + L ++ +N+D IE S K + V S E F +
Sbjct: 2214 HLQQDCDVPSRELRDLKLNQNMDLHIEEILKDFSESEFPSIKTEFQQVLSNRKEMTQFLE 2273
Query: 3825 EWKN--------KTALQK----LCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSK 3872
EW N K +QK +C V +R+ + E E RS SK
Sbjct: 2274 EWLNTRFDIEKLKNGIQKENDRICQVNNFFNNRIIAIMNESTE-------FEERSATISK 2326
Query: 3873 SYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDV 3932
+E+ D+++L +K N + SL G +V +
Sbjct: 2327 EWEQ-------------------DLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQDN- 2366
Query: 3933 AAEKGHWVILQNIHLVARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGIL 3992
+N H+ +R +K+ HE + E A E+ II +
Sbjct: 2367 ----------KNPHVTSRATQLTTEKIRELENSLHE------AKESAMHKESKIIK---M 2407
Query: 3993 ENAIKITNEPPTGMHANLHKA 4013
+ +++TN+ + A +H++
Sbjct: 2408 QKELEVTNDIIAKLQAKVHES 2428
Score = 39.3 bits (90), Expect = 0.089
Identities = 141/757 (18%), Positives = 290/757 (38%), Gaps = 139/757 (18%)
Query: 775 QYIQEVREILHNLQNRMQKAKQNI---EGISQAMKDWSANPLFERKDNKKEALLDLDGRI 831
Q + +RE L +Q K +Q++ E ++ K S F+ KD+ ALL ++ +
Sbjct: 1367 QLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDS---ALLRIEIEM 1423
Query: 832 ANLNKRYAAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSL 891
L+KR D +++++ E +L R ++ + D + + + + K L
Sbjct: 1424 LGLSKRLQESHD---EMKSVAKEKDDLQRL-------QEVLQSESDQLKENIKEIVAKHL 1473
Query: 892 S----FLMDNMVIDESIAPLFEIRMELDEDGL---TFNPTLEVGSDRGFLALIEGLVNDI 944
+ + + E + E+R+ L E T LE +D+ ++ + +I
Sbjct: 1474 ETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDK-----LQNKIQEI 1528
Query: 945 Y------NVARLIP--------------RLAKDRMNYKMD---LEDNTDLIEMREEVSSL 981
Y N+ ++ R AKD ++ LE L E +EE+ +
Sbjct: 1529 YEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQ-I 1587
Query: 982 VINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDDTIPKTPPTL 1041
+I +E + Q++ + + D L+E K + ++ + +T +
Sbjct: 1588 MIKEKEEMKRVQEALQ----IERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKM 1643
Query: 1042 AQFQEQIDSYE--KLYEEVSKCEN---TKVFHGWLQ-----CDCRPFKQALLSTIRRWGF 1091
+ + + +E KL E + EN T++ H L+ R +++ T++
Sbjct: 1644 CEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERD 1703
Query: 1092 MFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAATDNM 1151
K +L +T L E +K+ M L + + D L + V E+ NM
Sbjct: 1704 QLKENLRETITRDLEKQEE-LKIVHMHLKE--HQETIDKLRGI------VSEKTNEISNM 1754
Query: 1152 FEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQ------ANE 1205
+ L+ + + LK ++ EE+ + L E KL V L N
Sbjct: 1755 QKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENS 1814
Query: 1206 VSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKQQKSISAMEGIMEALSKSG 1265
+ L+ K Q+ + +H+ K +N+ QK +S ME +
Sbjct: 1815 NAKLQEKIQELKANEHQL--------------ITLKKDVNETQKKVSEMEQLK------- 1853
Query: 1266 GLFEVPVPDYKQLKACHREVRLLK-ELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKK 1324
KQ+K + L+ E ++ ++ ++E+ K+ + N+ +++ K
Sbjct: 1854 ----------KQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKL 1903
Query: 1325 FAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFK 1384
++ +E K D L EL+ + + ++ + +++ K
Sbjct: 1904 ERDQLKESLQETKARD---------------LEIQQELKTARMLSKEHKETVD--KLREK 1946
Query: 1385 MSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTG 1444
+SE+T +Q +L +DE++ + + K K L+ L + E + H +
Sbjct: 1947 ISEKTIQISDIQKDLDKSKDELQKKIQELQK-----KELQLL----RVKEDVNMSHKKIN 1997
Query: 1445 TMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEV 1481
M + + L V++ N ++K L L+E+
Sbjct: 1998 EMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEI 2034
Score = 37.0 bits (84), Expect = 0.44
Identities = 27/131 (20%), Positives = 63/131 (48%), Gaps = 8/131 (6%)
Query: 3029 LEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESA 3088
+EQ K + L + E++ +RL+ +++S A + DDL+ + ++E Q E+
Sbjct: 1406 MEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENI 1465
Query: 3089 DQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEAL 3148
+++ E++ ++E + + N++EK ET+++ + L EA+
Sbjct: 1466 KEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEK----ETEISTIQKQL----EAI 1517
Query: 3149 DTLNKNNLTEL 3159
+ +N + E+
Sbjct: 1518 NDKLQNKIQEI 1528
Score = 34.3 bits (77), Expect = 2.9
Identities = 186/1003 (18%), Positives = 389/1003 (38%), Gaps = 103/1003 (10%)
Query: 604 SLELQERLEVSMKHLKHVEHPVM---SGAEAKLTYQKYDEMMELLRCHRE--KIYQQWVA 658
+LEL+E+++ K +E+ + S EAK Q D EL E K+
Sbjct: 648 NLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQ-VDLEKELQSAFNEITKLTSLIDG 706
Query: 659 GVDQDCHFNLGQPLILRDAASNLI-HVNFSKAL---VAVLREVKYLNFQQQ---KEIPDS 711
V +D NL + D L V ++AL V +L E+K L + + KEI D
Sbjct: 707 KVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDK 766
Query: 712 AESLF----SENETFRKFVGNLELIVGWYNEVMKAVEFLLI-KSELEAIDVKLLSAETTL 766
+E L +++ F + V + G E+ K + L +S ++ D + + +T L
Sbjct: 767 SEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKT-L 825
Query: 767 FWNGEGVFQYIQEVREILHNLQNRMQKAKQNIEGISQAMK---DWSANPLFERKDNKKEA 823
+ E ++ + E E ++ + K Q + A+K + L E+ +E
Sbjct: 826 HMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQER 885
Query: 824 LLDLDGRIANLNKRYAAVRDAGVKIQAMVAENAELFRADTLSLPW-KDYVIYIDDMVLDE 882
L +++ L R + ++ + + ++ E + + +L KD + + + + E
Sbjct: 886 LNEMEQLKEQLENRDSTLQTVE-REKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIE 944
Query: 883 FDQFIRKSLSFLMDNMVIDESIAPLFEIRMELDEDGLTFNPTLEVGSDRGF-LALIEGLV 941
DQ + N+ E + E + E T + R + G
Sbjct: 945 RDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGET 1004
Query: 942 NDIYN-----VARLIPRLAKDRMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSF 996
D + + + AK+ D++DN ++IE + ++ SL+ +E E Q
Sbjct: 1005 KDEFQQKMVGIDKKQDLEAKNTQTLTADVKDN-EIIEQQRKIFSLI----QEKNELQQML 1059
Query: 997 ERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWT--DDTIPKTPPTLAQFQEQIDSYEKL 1054
E +E +K L +T E+ + D + K +AQ E+ + +K
Sbjct: 1060 ESVIAE-----KEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQ--EKNHAIKKE 1112
Query: 1055 YEEVSKCENTKVFHGWLQCDCRPFK---QALLSTIRRWGFMFKR-----HLSNHVTNSLA 1106
E C+ L+ + + Q LL+ M K+ +L N + N
Sbjct: 1113 GELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKEL 1172
Query: 1107 DLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYG 1166
LE M+ R+ L + L E +Y+ + + +KE Q + + + L+ I ++ G
Sbjct: 1173 TLE-HMETERLELAQKLNE-NYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATG 1230
Query: 1167 EEMPEEIHLKLQELPEHWANTKKLAIQV-KLTVAPLQANEVSILRRKCQQFELKQHEFRE 1225
+ EE+ + L EH +L V + T + ++ K Q+ HE +E
Sbjct: 1231 LQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQE 1290
Query: 1226 RFR--REAPFSFSDPNPYKSLNKQQ--KSISAMEGIMEALSKSGGLFEVPVPDYKQLKAC 1281
+E + N + L +Q K + + I + F+ + K L
Sbjct: 1291 LLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKE 1350
Query: 1282 HREVRLLKE--------LWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLD 1333
++ +KE L + + I++ ++ + + +N+++ D + K +M
Sbjct: 1351 RDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEM---- 1406
Query: 1334 KEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLAD 1393
+ F D+ + + E++ + +R + + V + + L +
Sbjct: 1407 ------EQFKPKDSALLRI--------EIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQE 1452
Query: 1394 LLQLNLHSYEDEVRNIVDKAVKESGMEKV----LKALDSTWSMMEFQHEPHPRTGTMMLK 1449
+LQ ++ ++ IV K ++ KV LK + T + + + + K
Sbjct: 1453 VLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQK 1512
Query: 1450 SSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLE 1509
E + + L+ N++Q + K +K+++ Q+K++ E+++ H +
Sbjct: 1513 QLEAINDKLQ-NKIQ---EIYEKEEQFNIKQISEVQEKVN----------ELKQFKEHRK 1558
Query: 1510 SIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEA 1552
+ + I +++ + R + +E + ++++ + V EA
Sbjct: 1559 AKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEA 1601
>gi|124249396 coiled-coil domain containing 30 [Homo sapiens]
Length = 783
Score = 45.8 bits (107), Expect = 0.001
Identities = 46/223 (20%), Positives = 101/223 (45%), Gaps = 29/223 (13%)
Query: 1275 YKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDK 1334
Y+ + HR+VR L++ +++ + T + ++Q + K+ + R D+
Sbjct: 411 YQNVDELHRQVRTLQDKENLLEM---------TCSQQQSRIQQQEALLKQLENEKRKYDE 461
Query: 1335 EMKTWDAFVGLDNTVKNVITSLRA----VSELQNPAIR---ERHWQQLMQATQVKFKMSE 1387
+K+ + ++ +LR + +L N +R E+H QQ ++ +VK++++
Sbjct: 462 HVKSNQELSEKLSKLQQEKEALREEYLRLLKLLNVHVRNYNEKHHQQKVKLQKVKYRLTN 521
Query: 1388 ETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTW---------SMMEFQHE 1438
E L D ++ +EDE+ + K KE ++ + A + T ++E +
Sbjct: 522 EVELRD---KRINQFEDEIGILQHKIEKEKAIQDQITAQNDTLLLEKRKLQEQVIEQEQL 578
Query: 1439 PHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEV 1481
H T+ S VL E+ Q+Q +L +++ + FL+ +
Sbjct: 579 IHSNKWTISSIQSRVLYMDKENKQLQENSLRLTQQIG-FLERI 620
>gi|34577114 cytomatrix protein p110 [Homo sapiens]
Length = 957
Score = 43.9 bits (102), Expect = 0.004
Identities = 86/381 (22%), Positives = 155/381 (40%), Gaps = 71/381 (18%)
Query: 3026 KTFLEQIKLYQNLLAKKRTELVA---KIERLENG---------LMKLQSTA--------- 3064
KT ++Q+K L+KK +EL+A K+E L N ++K TA
Sbjct: 433 KTKIDQLK---QELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQ 489
Query: 3065 SQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINK--- 3121
++VD L+ +L +E+ L +K + L + G A ++ K + + +E K+ V+ K
Sbjct: 490 TEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIE 549
Query: 3122 --------------NVTEKQKACETDLAKAEPALLAAQEAL--------------DTLNK 3153
N+ ++ K+ +TD + + AL +EAL + ++
Sbjct: 550 NLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDR 609
Query: 3154 NNLTELKSFGSP-PDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMG-KVDTFLDSL-- 3209
L E++SF D V A LT + K ++ G K D+ L SL
Sbjct: 610 ERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEI 669
Query: 3210 ---KKFDKEHIPEACLKAFKPYQGNPTFDPEF---IRSKSTAAAGLCSWC----INIVRF 3259
+K ++ EA LK + + +PEF I+ A+ C + R
Sbjct: 670 AIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLDKEASYYRDECGKAQAEVDRL 729
Query: 3260 YEVYCDVAPKRQALEEANAELAEAQEKLSRIKN-KIAELNANLSNLTSAFEKATAEKIKC 3318
E+ +V ++ ++ AEL + + +N K+A L N L E+++
Sbjct: 730 LEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHN-QQLEKKKNAQLLEEVRR 788
Query: 3319 QQEADATNRVILLANRLVGGL 3339
++++ A N L L+ L
Sbjct: 789 REDSMADNSQHLQIEELMNAL 809
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 42.0 bits (97), Expect = 0.014
Identities = 55/281 (19%), Positives = 122/281 (43%), Gaps = 60/281 (21%)
Query: 1188 KKLAIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKQ 1247
KK+ + + LQ NE S++R+ EL++ +E +++ + + +
Sbjct: 876 KKILAENSRKITVLQVNEKSLIRQYTTLVELERQLRKENEKQKNELLSMEAEVCEKIGCL 935
Query: 1248 QK----SISAMEGIMEALSKSGGLFEVPVPD--YKQLKACHREVRLLKELWDMVVVVNTS 1301
Q+ +I + + + + S L E+ + + Y +L A +R++ L K D ++V TS
Sbjct: 936 QRFKEMAIFKIAALQKVVDNSVSLSELELANKQYNELTAKYRDI-LQK---DNMLVQRTS 991
Query: 1302 IEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEM-----------KTWDAFVGLDN--- 1347
N+E ++ + + + S++KE+ + W+ L N
Sbjct: 992 ------------NLEHLECENISLKEQVESINKELEITKEKLHTIEQAWEQETKLGNESS 1039
Query: 1348 --------TVKNVITSLRAVSELQNPAIRER----HWQQLMQATQVKFKMSE------ET 1389
T ++++ + ++ L+ + ER H Q++ + + K E ET
Sbjct: 1040 MDKAKKSITNSDIVSISKKITMLEMKELNERQRAEHCQKMYEHLRTSLKQMEERNFELET 1099
Query: 1390 TLADLLQLNLHSYE------DEVRNIVDKAVKESGMEKVLK 1424
A+L ++NL + + DE+ + V KAV ++ +++L+
Sbjct: 1100 KFAELTKINLDAQKVEQMLRDELADSVSKAVSDADRQRILE 1140
Score = 37.0 bits (84), Expect = 0.44
Identities = 31/130 (23%), Positives = 63/130 (48%), Gaps = 13/130 (10%)
Query: 3030 EQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQ----VDDLKAK-----LAIQEAE 3080
E+I++ + K E V ++E++ + ++++ Q +D LK + L +QE
Sbjct: 230 EKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELT 289
Query: 3081 --LKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAE 3138
LK KNE D ++ V + E+ + D E ++ + + N+ EK K + D K+
Sbjct: 290 DLLKSKNEEDDPIMVAVNAKVEEWKLILSSKDDEIIEYQQMLHNLREKLKNAQLDADKSN 349
Query: 3139 PALLAAQEAL 3148
++A Q+ +
Sbjct: 350 --VMALQQGI 357
Score = 35.4 bits (80), Expect = 1.3
Identities = 51/241 (21%), Positives = 89/241 (36%), Gaps = 40/241 (16%)
Query: 3031 QIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQ 3090
Q+ ++ K +++A+ ERL L K A ++ K L I ++ + E +
Sbjct: 2187 QLSMHYESKTKGTEKIIAENERLRKELKKETDAAEKLRIAKNNLEILNEKMTVQLEETGK 2246
Query: 3091 LIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALL-------A 3143
+Q AE + AD + K V+ + K K ETD+AK ++
Sbjct: 2247 RLQF----AESRGPQLEGADSKSWKSIVVTRMYETKLKELETDIAKKNQSITDLKQLVKE 2302
Query: 3144 AQEALDTLNKNN------LTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKS-----W 3192
A E +NK N + LK + + + +L ++ K+K+
Sbjct: 2303 ATEREQKVNKYNEDLEQQIKILKHVPEGAETEQGLKRELQVLRLANHQLDKEKAELIHQI 2362
Query: 3193 KAAKIMMGKVDTFLDS---------------LKKFDKEHIPEACLKAFKPYQGNPTFDPE 3237
+A K G T D+ + +K+H+ E K K + FDP
Sbjct: 2363 EANKDQSGAESTIPDADQLKEKIKDLETQLKMSDLEKQHLKEEIKKLKKELE---NFDPS 2419
Query: 3238 F 3238
F
Sbjct: 2420 F 2420
Score = 35.0 bits (79), Expect = 1.7
Identities = 31/126 (24%), Positives = 63/126 (50%), Gaps = 7/126 (5%)
Query: 3029 LEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDD--LKAKLAIQEAELKQKNE 3086
LE+++ AK +L K+ +LEN L Q +A D L+ ++ E +L+QK+
Sbjct: 70 LEEVEKAGEEQAKFENQLKTKVMKLENELEMAQQSAGGRDTRFLRNEICQLEKQLEQKDR 129
Query: 3087 SADQLIQVVGIEAEKVSKEKAI----ADQEEVKVEVINKNVTEKQKACETDLAKAEPALL 3142
+ + + + E +KV+++ A+ A+ E K+ NK + +K + D+ + +
Sbjct: 130 ELEDMEKELEKE-KKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDIIDYQKQID 188
Query: 3143 AAQEAL 3148
+ +E L
Sbjct: 189 SQKETL 194
Score = 32.7 bits (73), Expect = 8.3
Identities = 56/265 (21%), Positives = 106/265 (40%), Gaps = 41/265 (15%)
Query: 3582 LEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVE---NLE--TTKHTAS 3636
+E+LK+ L + + K + + L + +AA + T+ E N++ +HT
Sbjct: 1727 VERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDRHTR- 1785
Query: 3637 EIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEK 3696
E++ +V + +K+ EA + + R + L LNDLN Q KA+N + +
Sbjct: 1786 ELKTQVEDLNENLLKLKEA---LKTSKNRENSLTDNLNDLNN---ELQKKQKAYNKILRE 1839
Query: 3697 AIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPV 3756
+ +E+K+++ LT + + L E ++ +V ++ +L
Sbjct: 1840 KEEIDQENDELKRQIKRLTSGLQGKPLTDNKQSLIE--------ELQRKVKKLENQLE-- 1889
Query: 3757 ELDFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKK------ 3810
G V VD + + L +E K + IEG + K+
Sbjct: 1890 ------------GKVEEVDLKPMKEKNAKEELIRWEEGKKWQAKIEGIRNKLKEKEGEVF 1937
Query: 3811 -LVESEAPEKEIFPKEWKNKTALQK 3834
L + K++F K K K LQ+
Sbjct: 1938 TLTKQLNTLKDLFAKADKEKLTLQR 1962
>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
Length = 2028
Score = 42.0 bits (97), Expect = 0.014
Identities = 63/343 (18%), Positives = 139/343 (40%), Gaps = 25/343 (7%)
Query: 3029 LEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNES- 3087
LE+ L L K+ +L KIE+L+ L + + + ++ L +L ++ +L+ E+
Sbjct: 489 LEESGLKCGELEKENHQLSKKIEKLQTQLEREKQSNQDLETLSEELIREKEQLQSDMETL 548
Query: 3088 -ADQLIQVVGIEAEKVSKEKA---IADQEEVKVEVINKNVTEKQKACETDLAKAEPALLA 3143
AD+ Q+ +E EK +A + ++ +V E K+V ++ KA + +A L
Sbjct: 549 KADKARQIKDLEQEKDHLNRAMWSLRERSQVSSEARMKDVEKENKALHQTVTEANGKLSQ 608
Query: 3144 AQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVD 3203
+ L++ +L + K G + + + L G++ + + ++
Sbjct: 609 LEFEKRQLHR-DLEQAKEKG---ERAEKLERELQRLQEENGRLAR---------KVTSLE 655
Query: 3204 TFLDSLKKFDKE----HIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRF 3259
T + ++ + E + L+ N + E + + L + + + R
Sbjct: 656 TATEKVEALEHESQGLQLENRTLRKSLDTLQNVSLQLEGLERDNKQ---LDAENLELRRL 712
Query: 3260 YEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQ 3319
E + K +E N +L +E+L + + + L L +++ +AE ++ Q
Sbjct: 713 VETMRFTSTKLAQMERENQQLEREKEELRKNVDLLKALGKKSERLELSYQSVSAENLRLQ 772
Query: 3320 QEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCG 3362
Q ++++ +G L +E +E R L G
Sbjct: 773 QSLESSSHKTQTLESELGELEAERQALRRDLEALRLANAQLEG 815
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 41.2 bits (95), Expect = 0.023
Identities = 63/303 (20%), Positives = 131/303 (43%), Gaps = 30/303 (9%)
Query: 3066 QVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQE----EVKVEVINK 3121
++++L+ L ++A ++ E+ +L + +E KE D E + K +V+ K
Sbjct: 1348 ELEELRKSLQEKDATIRTLQENNHRLSDSIAATSELERKEHEQTDSEIKQLKEKQDVLQK 1407
Query: 3122 NVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTA 3181
+ EK + AK++ L + + + +N+N L AV N+ ++IL
Sbjct: 1408 LLKEKDLLIK---AKSDQLLSSNENFTNKVNENELLR--------QAVTNLKERILILEM 1456
Query: 3182 PGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPY--QGNPTFDPEFI 3239
GK+ K ++ K + GK +T +L++ + + K F+ + + + +
Sbjct: 1457 DIGKL-KGENEKIVETYRGK-ETEYQALQETNMKFSMMLREKEFECHSMKEKALAFEQLL 1514
Query: 3240 RSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQ-----ALEEANAELAEAQEKLSRIKNKI 3294
+ K G + +N V+ + V + + AL++ E Q ++ R+++K
Sbjct: 1515 KEKEQGKTGELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMENTALQNEVQRLRDKE 1574
Query: 3295 AELNANL----SNLTSAFEKATAEKIKCQ-QEADATNRVILLANRLVGGL-ASENIRWAE 3348
N L ++L + + T E + + +EA +V +L +LV A EN
Sbjct: 1575 FRSNQELERLRNHLLESEDSYTREALAAEDREAKLRKKVTVLEEKLVSSSNAMENASHQA 1634
Query: 3349 SVE 3351
SV+
Sbjct: 1635 SVQ 1637
>gi|4502395 beclin 1 [Homo sapiens]
Length = 450
Score = 40.8 bits (94), Expect = 0.030
Identities = 33/130 (25%), Positives = 56/130 (43%), Gaps = 3/130 (2%)
Query: 3027 TFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNE 3086
T L+Q+ N+ + +E LE + + Q+ +LA++E L Q+ E
Sbjct: 143 TLLDQLDTQLNVTENECQNYKRCLEILEQ---MNEDDSEQLQMELKELALEEERLIQELE 199
Query: 3087 SADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQE 3146
++ ++V EKV E DQEE + + +Q + +L E + AQ
Sbjct: 200 DVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQT 259
Query: 3147 ALDTLNKNNL 3156
LD L K N+
Sbjct: 260 QLDKLKKTNV 269
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 40.8 bits (94), Expect = 0.030
Identities = 93/536 (17%), Positives = 206/536 (38%), Gaps = 60/536 (11%)
Query: 777 IQEVREILHNLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNK 836
IQ+++EIL +LQ R++ ++ + + ++ A + E DL ++
Sbjct: 434 IQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQS 493
Query: 837 RYAAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMD 896
+Y + +K V + +L S+ +Y + + V +E +++ L ++
Sbjct: 494 KY----EEAMKEVLSVQKQMKLGLVSPESM--DNYSHFHELRVTEEEINVLKQDLQNALE 547
Query: 897 NMVIDESIAPLFEIRMELDEDGLTFNPTLEVGSD--RGFLALIEGL------VNDIYNVA 948
++ E ++ E G P +E + + ++IE + + + Y A
Sbjct: 548 ESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEA 607
Query: 949 RLIPRLAKDRMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSF-----ERYSYLW 1003
+ KD + +M E + + +M+E ++ ++ K+ E + E Y
Sbjct: 608 QEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRK 667
Query: 1004 TDNLQEFMKNFLIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCEN 1063
+L++ ++ E L T+ + K L++ + Q Y K+ E+++ +
Sbjct: 668 RKSLEDVTAEYI---HKAEHEKLMQLTNVSRAKAEDALSEMKSQ---YSKVLNELTQLKQ 721
Query: 1064 TKVFHGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPL 1123
L+ + HL T A E K++ L
Sbjct: 722 ------------------LVDAQKENSVSITEHLQVITTLRTAAKEMEEKISN------L 757
Query: 1124 KEGDYDGLVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEH 1183
KE VEV ++ E +AA + P + + E L++ E + KL+E +
Sbjct: 758 KEHLASKEVEVAKLEKQLLEEKAAMTDAMVP-RSSYEKLQSSLESEVSVLASKLKESVKE 816
Query: 1184 WANTKKLAIQVKLTVAPLQANEVSI----------LRRKCQQFELKQHEFRERFRREAPF 1233
+Q++ V+ ++ + +I + Q+F+ Q E E R
Sbjct: 817 KEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESS 876
Query: 1234 SFSDPNPYKSLNKQQKSISAMEGIMEALSKSGGLFEVPVPDYKQLKACHREVRLLK 1289
S + + K +N+ K ++ ++ + +LS+ +QL+A ++V+ L+
Sbjct: 877 SKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ 932
>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
Length = 972
Score = 40.8 bits (94), Expect = 0.030
Identities = 93/536 (17%), Positives = 206/536 (38%), Gaps = 60/536 (11%)
Query: 777 IQEVREILHNLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNK 836
IQ+++EIL +LQ R++ ++ + + ++ A + E DL ++
Sbjct: 423 IQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQS 482
Query: 837 RYAAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMD 896
+Y + +K V + +L S+ +Y + + V +E +++ L ++
Sbjct: 483 KY----EEAMKEVLSVQKQMKLGLVSPESM--DNYSHFHELRVTEEEINVLKQDLQNALE 536
Query: 897 NMVIDESIAPLFEIRMELDEDGLTFNPTLEVGSD--RGFLALIEGL------VNDIYNVA 948
++ E ++ E G P +E + + ++IE + + + Y A
Sbjct: 537 ESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEA 596
Query: 949 RLIPRLAKDRMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSF-----ERYSYLW 1003
+ KD + +M E + + +M+E ++ ++ K+ E + E Y
Sbjct: 597 QEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRK 656
Query: 1004 TDNLQEFMKNFLIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCEN 1063
+L++ ++ E L T+ + K L++ + Q Y K+ E+++ +
Sbjct: 657 RKSLEDVTAEYI---HKAEHEKLMQLTNVSRAKAEDALSEMKSQ---YSKVLNELTQLKQ 710
Query: 1064 TKVFHGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPL 1123
L+ + HL T A E K++ L
Sbjct: 711 ------------------LVDAQKENSVSITEHLQVITTLRTAAKEMEEKISN------L 746
Query: 1124 KEGDYDGLVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEH 1183
KE VEV ++ E +AA + P + + E L++ E + KL+E +
Sbjct: 747 KEHLASKEVEVAKLEKQLLEEKAAMTDAMVP-RSSYEKLQSSLESEVSVLASKLKESVKE 805
Query: 1184 WANTKKLAIQVKLTVAPLQANEVSI----------LRRKCQQFELKQHEFRERFRREAPF 1233
+Q++ V+ ++ + +I + Q+F+ Q E E R
Sbjct: 806 KEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESS 865
Query: 1234 SFSDPNPYKSLNKQQKSISAMEGIMEALSKSGGLFEVPVPDYKQLKACHREVRLLK 1289
S + + K +N+ K ++ ++ + +LS+ +QL+A ++V+ L+
Sbjct: 866 SKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ 921
>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
Length = 951
Score = 40.8 bits (94), Expect = 0.030
Identities = 93/536 (17%), Positives = 206/536 (38%), Gaps = 60/536 (11%)
Query: 777 IQEVREILHNLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNK 836
IQ+++EIL +LQ R++ ++ + + ++ A + E DL ++
Sbjct: 402 IQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQS 461
Query: 837 RYAAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMD 896
+Y + +K V + +L S+ +Y + + V +E +++ L ++
Sbjct: 462 KY----EEAMKEVLSVQKQMKLGLVSPESM--DNYSHFHELRVTEEEINVLKQDLQNALE 515
Query: 897 NMVIDESIAPLFEIRMELDEDGLTFNPTLEVGSD--RGFLALIEGL------VNDIYNVA 948
++ E ++ E G P +E + + ++IE + + + Y A
Sbjct: 516 ESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEA 575
Query: 949 RLIPRLAKDRMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSF-----ERYSYLW 1003
+ KD + +M E + + +M+E ++ ++ K+ E + E Y
Sbjct: 576 QEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRK 635
Query: 1004 TDNLQEFMKNFLIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCEN 1063
+L++ ++ E L T+ + K L++ + Q Y K+ E+++ +
Sbjct: 636 RKSLEDVTAEYI---HKAEHEKLMQLTNVSRAKAEDALSEMKSQ---YSKVLNELTQLKQ 689
Query: 1064 TKVFHGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPL 1123
L+ + HL T A E K++ L
Sbjct: 690 ------------------LVDAQKENSVSITEHLQVITTLRTAAKEMEEKISN------L 725
Query: 1124 KEGDYDGLVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEH 1183
KE VEV ++ E +AA + P + + E L++ E + KL+E +
Sbjct: 726 KEHLASKEVEVAKLEKQLLEEKAAMTDAMVP-RSSYEKLQSSLESEVSVLASKLKESVKE 784
Query: 1184 WANTKKLAIQVKLTVAPLQANEVSI----------LRRKCQQFELKQHEFRERFRREAPF 1233
+Q++ V+ ++ + +I + Q+F+ Q E E R
Sbjct: 785 KEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESS 844
Query: 1234 SFSDPNPYKSLNKQQKSISAMEGIMEALSKSGGLFEVPVPDYKQLKACHREVRLLK 1289
S + + K +N+ K ++ ++ + +LS+ +QL+A ++V+ L+
Sbjct: 845 SKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ 900
>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 40.8 bits (94), Expect = 0.030
Identities = 93/536 (17%), Positives = 206/536 (38%), Gaps = 60/536 (11%)
Query: 777 IQEVREILHNLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNK 836
IQ+++EIL +LQ R++ ++ + + ++ A + E DL ++
Sbjct: 431 IQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQS 490
Query: 837 RYAAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMD 896
+Y + +K V + +L S+ +Y + + V +E +++ L ++
Sbjct: 491 KY----EEAMKEVLSVQKQMKLGLVSPESM--DNYSHFHELRVTEEEINVLKQDLQNALE 544
Query: 897 NMVIDESIAPLFEIRMELDEDGLTFNPTLEVGSD--RGFLALIEGL------VNDIYNVA 948
++ E ++ E G P +E + + ++IE + + + Y A
Sbjct: 545 ESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEA 604
Query: 949 RLIPRLAKDRMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSF-----ERYSYLW 1003
+ KD + +M E + + +M+E ++ ++ K+ E + E Y
Sbjct: 605 QEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRK 664
Query: 1004 TDNLQEFMKNFLIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCEN 1063
+L++ ++ E L T+ + K L++ + Q Y K+ E+++ +
Sbjct: 665 RKSLEDVTAEYI---HKAEHEKLMQLTNVSRAKAEDALSEMKSQ---YSKVLNELTQLKQ 718
Query: 1064 TKVFHGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPL 1123
L+ + HL T A E K++ L
Sbjct: 719 ------------------LVDAQKENSVSITEHLQVITTLRTAAKEMEEKISN------L 754
Query: 1124 KEGDYDGLVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEH 1183
KE VEV ++ E +AA + P + + E L++ E + KL+E +
Sbjct: 755 KEHLASKEVEVAKLEKQLLEEKAAMTDAMVP-RSSYEKLQSSLESEVSVLASKLKESVKE 813
Query: 1184 WANTKKLAIQVKLTVAPLQANEVSI----------LRRKCQQFELKQHEFRERFRREAPF 1233
+Q++ V+ ++ + +I + Q+F+ Q E E R
Sbjct: 814 KEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESS 873
Query: 1234 SFSDPNPYKSLNKQQKSISAMEGIMEALSKSGGLFEVPVPDYKQLKACHREVRLLK 1289
S + + K +N+ K ++ ++ + +LS+ +QL+A ++V+ L+
Sbjct: 874 SKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ 929
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 157,319,475
Number of Sequences: 37866
Number of extensions: 6823797
Number of successful extensions: 20381
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 139
Number of HSP's that attempted gapping in prelim test: 18846
Number of HSP's gapped (non-prelim): 1327
length of query: 4470
length of database: 18,247,518
effective HSP length: 123
effective length of query: 4347
effective length of database: 13,590,000
effective search space: 59075730000
effective search space used: 59075730000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 73 (32.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.