Search of human proteins with 119395709

Search of human proteins with 119395709

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|119395709 coagulation factor XIII A1 subunit precursor [Homo
sapiens]
         (732 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|119395709 coagulation factor XIII A1 subunit precursor [Homo ...  1499   0.0  
gi|4507475 transglutaminase 1 [Homo sapiens]                          576   e-164
gi|39777597 transglutaminase 2 isoform a [Homo sapiens]               417   e-116
gi|189458821 transglutaminase 3 precursor [Homo sapiens]              411   e-114
gi|94981556 transglutaminase 5 isoform 1 [Homo sapiens]               404   e-112
gi|148664232 transglutaminase 6 [Homo sapiens]                        398   e-110
gi|156627577 transglutaminase 4 (prostate) [Homo sapiens]             397   e-110
gi|39777599 transglutaminase 2 isoform b [Homo sapiens]               392   e-109
gi|16445035 transglutaminase 7 [Homo sapiens]                         363   e-100
gi|4759230 transglutaminase 5 isoform 2 [Homo sapiens]                359   6e-99
gi|166362737 erythrocyte membrane protein band 4.2 isoform 2 [Ho...   236   6e-62
gi|166362735 erythrocyte membrane protein band 4.2 isoform 1 [Ho...   236   6e-62
gi|4506339 peroxisomal biogenesis factor 19 isoform a [Homo sapi...    30   8.0  

>gi|119395709 coagulation factor XIII A1 subunit precursor [Homo
           sapiens]
          Length = 732

 Score = 1499 bits (3881), Expect = 0.0
 Identities = 732/732 (100%), Positives = 732/732 (100%)

Query: 1   MSETSRTAFGGRRAVPPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDT 60
           MSETSRTAFGGRRAVPPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDT
Sbjct: 1   MSETSRTAFGGRRAVPPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDT 60

Query: 61  NKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPV 120
           NKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPV
Sbjct: 61  NKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPV 120

Query: 121 PIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETD 180
           PIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETD
Sbjct: 121 PIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETD 180

Query: 181 TYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCL 240
           TYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCL
Sbjct: 181 TYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCL 240

Query: 241 YVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDIL 300
           YVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDIL
Sbjct: 241 YVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDIL 300

Query: 301 LEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLEEDGN 360
           LEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLEEDGN
Sbjct: 301 LEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLEEDGN 360

Query: 361 VNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKH 420
           VNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKH
Sbjct: 361 VNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKH 420

Query: 421 GHVCFQFDAPFVFAEVNSDLIYITAKKDGTHVVENVDATHIGKLIVTKQIGGDGMMDITD 480
           GHVCFQFDAPFVFAEVNSDLIYITAKKDGTHVVENVDATHIGKLIVTKQIGGDGMMDITD
Sbjct: 421 GHVCFQFDAPFVFAEVNSDLIYITAKKDGTHVVENVDATHIGKLIVTKQIGGDGMMDITD 480

Query: 481 TYKFQEGQEEERLALETALMYGAKKPLNTEGVMKSRSNVDMDFEVENAVLGKDFKLSITF 540
           TYKFQEGQEEERLALETALMYGAKKPLNTEGVMKSRSNVDMDFEVENAVLGKDFKLSITF
Sbjct: 481 TYKFQEGQEEERLALETALMYGAKKPLNTEGVMKSRSNVDMDFEVENAVLGKDFKLSITF 540

Query: 541 RNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLL 600
           RNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLL
Sbjct: 541 RNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLL 600

Query: 601 EQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVTVEFTNPLKET 660
           EQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVTVEFTNPLKET
Sbjct: 601 EQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVTVEFTNPLKET 660

Query: 661 LRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYG 720
           LRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYG
Sbjct: 661 LRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYG 720

Query: 721 ELDVQIQRRPSM 732
           ELDVQIQRRPSM
Sbjct: 721 ELDVQIQRRPSM 732


>gi|4507475 transglutaminase 1 [Homo sapiens]
          Length = 817

 Score =  576 bits (1485), Expect = e-164
 Identities = 302/692 (43%), Positives = 421/692 (60%), Gaps = 4/692 (0%)

Query: 39  GVNLQEFLNVTSVHLFKERWDTNKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRD 98
           G   +  L V  V L   R D N+ +HHTD+YE ++LIVRRGQ F++ +  SR Y+   D
Sbjct: 103 GTIREGMLVVNGVDLLSSRSDQNRREHHTDEYEYDELIVRRGQPFHMLLLLSRTYESS-D 161

Query: 99  LFRVEYVIGRYPQENKGTYIPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKF 158
              +E +IG  P+  KGT++ +P V +  SG W A++V    +++ L + +SP  I+GKF
Sbjct: 162 RITLELLIGNNPEVGKGTHVIIP-VGKGGSGGWKAQVVKASGQNLNLRVHTSPNAIIGKF 220

Query: 159 RMYVAVWTPYGVLRTSRNPETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEV 218
           +  V   +  G  +   +P  + YILFNPWC +D VY+D+E  R+EYVLN+ G I+YG  
Sbjct: 221 QFTVRTQSDAGEFQLPFDPRNEIYILFNPWCPEDIVYVDHEDWRQEYVLNESGRIYYGTE 280

Query: 219 NDIKTRSWSYGQFEDGILDTCLYVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVG 278
             I  R+W+YGQF+ G+LD CLY++DR  M   GRG+P+ VSRV SAMVN+ DD GVL+G
Sbjct: 281 AQIGERTWNYGQFDHGVLDACLYILDRRGMPYGGRGDPVNVSRVISAMVNSLDDNGVLIG 340

Query: 279 SWDNIYAYGVPPSAWTGSVDILLEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTN 338
           +W   Y+ G  PSAW GSV+ILL Y  +   V YGQCWVFAGV  T LRCLG+  R VTN
Sbjct: 341 NWSGDYSRGTNPSAWVGSVEILLSYLRTGYSVPYGQCWVFAGVTTTVLRCLGLATRTVTN 400

Query: 339 YFSAHDNDANLQMDIFLEEDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDS 398
           + SAHD D +L MDI+ +E+      L  DSVWN+H WN+ WM RPDLP GF GWQ VD+
Sbjct: 401 FNSAHDTDTSLTMDIYFDENMKPLEHLNHDSVWNFHVWNDCWMKRPDLPSGFDGWQVVDA 460

Query: 399 TPQENSDGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYITAKKDGTHVVENVDA 458
           TPQE S G++ CGP SV++IK+G V  ++D PF+FAEVNSD +Y   + DG+  +  V+ 
Sbjct: 461 TPQETSSGIFCCGPCSVESIKNGLVYMKYDTPFIFAEVNSDKVYWQRQDDGSFKIVYVEE 520

Query: 459 THIGKLIVTKQIGGDGMMDITDTYKFQEGQEEERLALETALMYGAKKPLNTEGVMKSRSN 518
             IG LIVTK I  +   DIT  YK  EG + ER A+ETA  +G+K   N      S  +
Sbjct: 521 KAIGTLIVTKAISSNMREDITYLYKHPEGSDAERKAVETAAAHGSKP--NVYANRGSAED 578

Query: 519 VDMDFEVENAVLGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTL 578
           V M  E ++AV+G+D  +S+   N+S +R T+  +L  ++TFYTGV    FK+   +V L
Sbjct: 579 VAMQVEAQDAVMGQDLMVSVMLINHSSSRRTVKLHLYLSVTFYTGVSGTIFKETKKEVEL 638

Query: 579 EPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVR 638
            P +  +  + +   EY   L++Q ++   V+  + E+  VLAKQ +  L  P++ + + 
Sbjct: 639 APGASDRVTMPVAYKEYRPHLVDQGAMLLNVSGHVKESGQVLAKQHTFRLRTPDLSLTLL 698

Query: 639 GTQVVGSDMTVTVEFTNPLKETLRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRP 698
           G  VVG +  V + F NPL  TL NV   L+G G+ RP      +I  N TV   +   P
Sbjct: 699 GAAVVGQECEVQIVFKNPLPVTLTNVVFRLEGSGLQRPKILNVGDIGGNETVTLRQSFVP 758

Query: 699 WVSGHRKLIASMSSDSLRHVYGELDVQIQRRP 730
              G R+LIAS+ S  L  V+G + V +   P
Sbjct: 759 VRPGPRQLIASLDSPQLSQVHGVIQVDVAPAP 790


>gi|39777597 transglutaminase 2 isoform a [Homo sapiens]
          Length = 687

 Score =  417 bits (1072), Expect = e-116
 Identities = 262/685 (38%), Positives = 355/685 (51%), Gaps = 32/685 (4%)

Query: 59  DTNKVDHHTDKYENNKLIVRRGQSFYVQIDFS-RPYDPRRDLFRVEYVIGRYPQENKGTY 117
           +TN  DHHT      KL+VRRGQ F++ + F  R Y+   D      V G  P +  GT 
Sbjct: 15  ETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFSVVTGPAPSQEAGTK 74

Query: 118 IPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNP 177
              P+   ++ G W A +V ++D ++ L + +     +G +R+ +   T Y   + S   
Sbjct: 75  ARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLEASTGY---QGSSFV 131

Query: 178 ETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILD 237
                +LFN WC  DAVYLD+E+ER+EYVL   G I+ G    IK   W++GQFEDGILD
Sbjct: 132 LGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPWNFGQFEDGILD 191

Query: 238 TCLYVMD-------RAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPP 290
            CL ++D        A  D S R +P+ V RV S MVN  DD+GVL+G WDN Y  GV P
Sbjct: 192 ICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGRWDNNYGDGVSP 251

Query: 291 SAWTGSVDILLEYRSSE-NPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANL 349
            +W GSVDIL  +++     V+YGQCWVFA V  T LRCLGIP R+VTNY SAHD ++NL
Sbjct: 252 MSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQNSNL 311

Query: 350 QMDIFLEEDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYR 409
            ++ F  E G +    + + +WN+HCW E+WMTRPDL  G+ GWQA+D TPQE S+G Y 
Sbjct: 312 LIEYFRNEFGEIQGDKS-EMIWNFHCWVESWMTRPDLQPGYEGWQALDPTPQEKSEGTYC 370

Query: 410 CGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYITAKKDGTHVVENVDATHIGKLIVTKQ 469
           CGP  V+AIK G +  ++DAPFVFAEVN+D++    + DG+       +  +G  I TK 
Sbjct: 371 CGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSLIVGLKISTKS 430

Query: 470 IGGDGMMDITDTYKFQEGQEEERLALETA--LMYGAKKPLNTEGVMKSRSNVDMDFEVEN 527
           +G D   DIT TYK+ EG  EER A   A  L   A+K   T   M+ R    M+     
Sbjct: 431 VGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKE-ETGMAMRIRVGQSMN----- 484

Query: 528 AVLGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEF-KKETFDVTLEPLSFKKE 586
             +G DF +     NN+   Y     L A    Y G+   E   K   ++ LEP S K  
Sbjct: 485 --MGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSEKSV 542

Query: 587 AVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSD 646
            + I   +Y   L E   +              L  ++   L  PEI I++ G       
Sbjct: 543 PLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQKRK 602

Query: 647 MTVTVEFTNPLKETLRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEV-----CRPWVS 701
           +   V   NPL   L      ++G G+T   K +  EI P+     EEV       P   
Sbjct: 603 LVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTV--EI-PDPVEAGEEVKVRMDLLPLHM 659

Query: 702 GHRKLIASMSSDSLRHVYGELDVQI 726
           G  KL+ +  SD L+ V G  +V I
Sbjct: 660 GLHKLVVNFESDKLKAVKGFRNVII 684


>gi|189458821 transglutaminase 3 precursor [Homo sapiens]
          Length = 693

 Score =  411 bits (1056), Expect = e-114
 Identities = 240/694 (34%), Positives = 375/694 (54%), Gaps = 38/694 (5%)

Query: 58  WDT--NKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVI--GRYPQEN 113
           W T  N+  HHTDK+ + +LI+RRGQ+F V +  ++         R+E+++  G YP E+
Sbjct: 11  WQTAFNRQAHHTDKFSSQELILRRGQNFQVLMIMNKGLGSNE---RLEFIVSTGPYPSES 67

Query: 114 KGTYIPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRT 173
             T    P+ S   SG W A +      ++ +SI S     +G++ M + +++  G+   
Sbjct: 68  AMTKAVFPL-SNGSSGGWSAVLQASNGNTLTISISSPASAPIGRYTMALQIFSQGGI--- 123

Query: 174 SRNPETDTYIL-FNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFE 232
             + +  T+IL FNPW   D+V++ N  EREEYV  D G+IF G  N I    W++GQFE
Sbjct: 124 -SSVKLGTFILLFNPWLNVDSVFMGNHAEREEYVQEDAGIIFVGSTNRIGMIGWNFGQFE 182

Query: 233 DGILDTCLYVMDR-------AQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYA 285
           + IL  CL ++DR       A  D++ R +P  V RV SAM+N+ DD GVL G+W   Y 
Sbjct: 183 EDILSICLSILDRSLNFRRDAATDVASRNDPKYVGRVLSAMINSNDDNGVLAGNWSGTYT 242

Query: 286 YGVPPSAWTGSVDILLEYRSSE-NPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHD 344
            G  P +W GSV+IL  ++ S  +PVRYGQCWVFAG  NT LR LGIP+R++TN+ SAHD
Sbjct: 243 GGRDPRSWNGSVEILKNWKKSGFSPVRYGQCWVFAGTLNTALRSLGIPSRVITNFNSAHD 302

Query: 345 NDANLQMDIFLEEDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENS 404
            D NL +D++ +  GN   K   DSVWN+H WNE W  R DL   +GGWQ +D+TPQE S
Sbjct: 303 TDRNLSVDVYYDPMGNPLDK-GSDSVWNFHVWNEGWFVRSDLGPSYGGWQVLDATPQERS 361

Query: 405 DGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDLI-YITAKKDGTHVVENVDATHIGK 463
            G+++CGPASV  ++ G V   FD PF+FAEVN+D I ++     G     +V++  IG+
Sbjct: 362 QGVFQCGPASVIGVREGDVQLNFDMPFIFAEVNADRITWLYDNTTGKQWKNSVNSHTIGR 421

Query: 464 LIVTKQIGGDGMMDITDTYKFQEGQEEERLALETALMYGAKKPLNTEGVMKSRSNVDMDF 523
            I TK +G +  MD+TD YK+ EG ++ER   + AL  G  KP NT     S   ++ + 
Sbjct: 422 YISTKAVGSNARMDVTDKYKYPEGSDQERQVFQKAL--GKLKP-NTPFAATSSMGLETEE 478

Query: 524 EVENAV----------LGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKET 573
           +  + +          +GK+  L +  +N S +  T+T  ++A    Y G    E  K++
Sbjct: 479 QEPSIIGKLKVAGMLAVGKEVNLVLLLKNLSRDTKTVTVNMTAWTIIYNGTLVHEVWKDS 538

Query: 574 FDVTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEI 633
             ++L+P    +  + I   +Y   L     +      ++ +  +V+  ++  +L  P +
Sbjct: 539 ATMSLDPEEEAEHPIKISYAQYEKYLKSDNMIRITAVCKVPDESEVVV-ERDIILDNPTL 597

Query: 634 IIKVRGTQVVGSDMTVTVEFTNPLKETLRNVWVHLDGPGVTRPMKKM-FREIRPNSTVQW 692
            ++V     V   + V + F+NPL E +R+  + ++G G+     K+    + P    + 
Sbjct: 598 TLEVLNEARVRKPVNVQMLFSNPLDEPVRDCVLMVEGSGLLLGNLKIDVPTLGPKEGSRV 657

Query: 693 EEVCRPWVSGHRKLIASMSSDSLRHVYGELDVQI 726
                P  SG ++L+A  S +    +   L + +
Sbjct: 658 RFDILPSRSGTKQLLADFSCNKFPAIKAMLSIDV 691


>gi|94981556 transglutaminase 5 isoform 1 [Homo sapiens]
          Length = 720

 Score =  404 bits (1039), Expect = e-112
 Identities = 239/703 (33%), Positives = 363/703 (51%), Gaps = 40/703 (5%)

Query: 61  NKVDHHTDKYENNKLIVRRGQSFYVQIDF-SRPYDPRRDLFRVEYVIGRYPQENKGTYIP 119
           N V HHT++   + L+VRRGQ+F + + F +R + P  D        G  P    GT   
Sbjct: 17  NNVRHHTEEITVDHLLVRRGQAFNLTLYFRNRSFQPGLDNIIFVVETGPLPDLALGTRAV 76

Query: 120 VPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPET 179
             +        W A +      S  +S+ + P   VG++ + + + +  G +   +  E 
Sbjct: 77  FSLARHHSPSPWIAWLETNGATSTEVSLCAPPTAAVGRYLLKIHIDSFQGSVTAYQLGEF 136

Query: 180 DTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTC 239
              +LFNPWC +DAVYLD+E +R+EYV+ND G I+ G  N I+   W+YGQFED I+D C
Sbjct: 137 --ILLFNPWCPEDAVYLDSEPQRQEYVMNDYGFIYQGSKNWIRPCPWNYGQFEDKIIDIC 194

Query: 240 LYVMDRA-------QMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSA 292
           L ++D++         D + RG+P+ VSRV  AM+N+ DD GVL G+W   Y  G  P+ 
Sbjct: 195 LKLLDKSLHFQTDPATDCALRGSPVYVSRVVCAMINSNDDNGVLNGNWSENYTDGANPAE 254

Query: 293 WTGSVDILLEYRSSE-NPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQM 351
           WTGSV IL ++ ++   PVRYGQCWVFA V  T +RCLGIP R++TN+ S HD D NL +
Sbjct: 255 WTGSVAILKQWNATGCQPVRYGQCWVFAAVMCTVMRCLGIPTRVITNFDSGHDTDGNLII 314

Query: 352 DIFLEEDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCG 411
           D + +  G +     KD++WN+H WNE WM R DLP  +GGWQ +D+TPQE S+G+Y CG
Sbjct: 315 DEYYDNTGRILGNKKKDTIWNFHVWNECWMARKDLPPAYGGWQVLDATPQEMSNGVYCCG 374

Query: 412 PASVQAIKHGHVCFQFDAPFVFAEVNSDLIYITAKKDGTHVVENVDATHIGKLIVTKQIG 471
           PASV+AIK G V   +D PFVF+ VN+D +    +  G     + D + +G  I TK I 
Sbjct: 375 PASVRAIKEGEVDLNYDTPFVFSMVNADCMSWLVQ-GGKEQKLHQDTSSVGNFISTKSIQ 433

Query: 472 GDGMMDITDTYKFQEGQEEERLAL-------------------------ETALMYGAKKP 506
            D   DIT+ YK++EG  +ER                             T+L   + + 
Sbjct: 434 SDERDDITENYKYEEGSLQERQVFLKALQKLKARSFHGSQRGAELQPSRPTSLSQDSPRS 493

Query: 507 LNTEGVMKSRS-NVDMDFEV-ENAVLGKDFKLSITFRNNSHNRYTITAYLSANITFYTGV 564
           L+T  +  S    V + F++ +   +G+D    +   N S     +   LSA    + G 
Sbjct: 494 LHTPSLRPSDVVQVSLKFKLLDPPNMGQDICFVLLALNMSSQFKDLKVNLSAQSLLHDGS 553

Query: 565 PKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQK 624
           P + F ++T  +TL P   K     I   +Y   L     +          + + +   K
Sbjct: 554 PLSPFWQDTAFITLSPKEAKTYPCKISYSQYSQYLSTDKLIRISALGEEKSSPEKILVNK 613

Query: 625 STVLTIPEIIIKVRGTQVVGSDMTVTVEFTNPLKETLRNVWVHLDGPGVTRPMKKMFREI 684
              L+ P I I V G  VV   +++ V F+NPL E + +  + ++G G+ +  +K+F  +
Sbjct: 614 IITLSYPSITINVLGAAVVNQPLSIQVIFSNPLSEQVEDCVLTVEGSGLFKKQQKVFLGV 673

Query: 685 -RPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYGELDVQI 726
            +P           P+ SG R++ A+M S+  + + G  +V +
Sbjct: 674 LKPQHQASIILETVPFKSGQRQIQANMRSNKFKDIKGYRNVYV 716


>gi|148664232 transglutaminase 6 [Homo sapiens]
          Length = 706

 Score =  398 bits (1022), Expect = e-110
 Identities = 243/710 (34%), Positives = 374/710 (52%), Gaps = 40/710 (5%)

Query: 46  LNVTSVHLFKERWDTNKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYV 105
           + VT V   + R   N   HHT +Y   +L+VRRGQSF + ++ SR  D    L    + 
Sbjct: 4   IRVTKVDWQRSR---NGAAHHTQEYPCPELVVRRGQSFSLTLELSRALDCEEILI---FT 57

Query: 106 IGRYPQENKGTYIPVPI-VSELQSGK-WGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVA 163
           +   P+ ++  +       SEL+ G+ W A    + ++++ +S+ S P  ++G++ + + 
Sbjct: 58  METGPRASEALHTKAVFQTSELERGEGWTAAREAQMEKTLTVSLASPPSAVIGRYLLSIR 117

Query: 164 VWTPYGVLRTSRNPETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKT 223
           + +     + S     +  +LFNPWC +D V+L +E+ER+EYVL+D G+IF G    I+ 
Sbjct: 118 LSSHR---KHSNRRLGEFVLLFNPWCAEDDVFLASEEERQEYVLSDSGIIFRGVEKHIRA 174

Query: 224 RSWSYGQFEDGILDTCLYVMDRAQ-------MDLSGRGNPIKVSRVGSAMVNAKDDEGVL 276
           + W+YGQFE+ IL+ CL ++DR+         D+S R NPI V+RV SAMVN+ +D GV+
Sbjct: 175 QGWNYGQFEEDILNICLSILDRSPGHQNNPATDVSCRHNPIYVTRVISAMVNSNNDRGVV 234

Query: 277 VGSWDNIYAYGVPPSAWTGSVDILLEY-RSSENPVRYGQCWVFAGVFNTFLRCLGIPARI 335
            G W   Y  G  P  W GSV IL ++ +    PV+YGQCWVFAGV  T LRCLGI  R+
Sbjct: 235 QGQWQGKYGGGTSPLHWRGSVAILQKWLKGRYKPVKYGQCWVFAGVLCTVLRCLGIATRV 294

Query: 336 VTNYFSAHDNDANLQMDIFLEEDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQA 395
           V+N+ SAHD D NL +D +++  G     LT+DS+WN+H WNE+W  R DL   + GWQ 
Sbjct: 295 VSNFNSAHDTDQNLSVDKYVDSFGRTLEDLTEDSMWNFHVWNESWFARQDLGPSYNGWQV 354

Query: 396 VDSTPQENSDGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYITAKKDGTHVVEN 455
           +D+TPQE S+G++RCGPASV AI+ G V    D PFVFAEVN+D I     +D +     
Sbjct: 355 LDATPQEESEGVFRCGPASVTAIREGDVHLAHDGPFVFAEVNADYITWLWHEDESRERVY 414

Query: 456 VDATHIGKLIVTKQIGGDGMMDITDTYKFQEGQEEERLALETAL--MYGAKKPLNTEGVM 513
            +   IG+ I TK +G D  +DITD YK+ EG  +ER     A+  ++G +       + 
Sbjct: 415 SNTKKIGRCISTKAVGSDSRVDITDLYKYPEGSRKERQVYSKAVNRLFGVEASGRRIWIR 474

Query: 514 K---------------SRSNVDMDFEV-ENAVLGKDFKLSITFRNNSHNRYTITAYLSAN 557
           +               ++ ++   F+V E  +LG D +L++   N +     +   LS  
Sbjct: 475 RAGGRCLWRDDLLEPATKPSIAGKFKVLEPPMLGHDLRLALCLANLTSRAQRVRVNLSGA 534

Query: 558 ITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETR 617
              YT  P AE   E+  V L P   K+  + I   +Y   L E   +       + +  
Sbjct: 535 TILYTRKPVAEILHESHAVRLGPQEEKRIPITISYSKYKEDLTEDKKILLAAMCLVTKGE 594

Query: 618 DVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVTVEFTNPLKETLRNVWVHLDGPGVTRPM 677
            +L ++  T+     I IKV G  +VG  +TV V   NPL E +++  + ++G G+ +  
Sbjct: 595 KLLVEKDITLEDF--ITIKVLGPAMVGVAVTVEVTVVNPLIERVKDCALMVEGSGLLQEQ 652

Query: 678 KKM-FREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYGELDVQI 726
             +    + P      +    P  SG R+L   + S     + G + V +
Sbjct: 653 LSIDVPTLEPQERASVQFDITPSKSGPRQLQVDLVSPHFPDIKGFVIVHV 702


>gi|156627577 transglutaminase 4 (prostate) [Homo sapiens]
          Length = 684

 Score =  397 bits (1021), Expect = e-110
 Identities = 222/676 (32%), Positives = 366/676 (54%), Gaps = 19/676 (2%)

Query: 61  NKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPV 120
           N V HHT +++ +  + RRGQ F++++  ++P      L ++E+  G  P   K T + +
Sbjct: 20  NAVSHHTWEFQTSSPVFRRGQVFHLRLVLNQPLQSYHQL-KLEFSTGPNPSIAKHTLVVL 78

Query: 121 PIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETD 180
              +      W A +     + V +++ SSP  I+GK+++ V   T   +L++  N    
Sbjct: 79  DPRTPSDHYNWQATLQNESGKEVTVAVTSSPNAILGKYQLNVK--TGNHILKSEENI--- 133

Query: 181 TYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCL 240
            Y+LFNPWC++D V++ +E ER+EY+LND G  + G    IK + W++GQFE  +LD C+
Sbjct: 134 LYLLFNPWCKEDMVFMPDEDERKEYILNDTGCHYVGAARSIKCKPWNFGQFEKNVLDCCI 193

Query: 241 YVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDIL 300
            ++  + +  + R +P+ V R   AM++ +  +GVL+G+W   Y  G  P  WTGS  IL
Sbjct: 194 SLLTESSLKPTDRRDPVLVCRAMCAMMSFEKGQGVLIGNWTGDYEGGTAPYKWTGSAPIL 253

Query: 301 LEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLEEDGN 360
            +Y +++  V +GQCWVFAG+  T LR LGIPAR VT + SAHD + NL +D ++ E+G 
Sbjct: 254 QQYYNTKQAVCFGQCWVFAGILTTVLRALGIPARSVTGFDSAHDTERNLTVDTYVNENGE 313

Query: 361 VNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKH 420
             + +T DSVWN+H W +AWM RPDLP G+ GWQAVD+TPQE S G++ CGP+ + AI+ 
Sbjct: 314 KITSMTHDSVWNFHVWTDAWMKRPDLPKGYDGWQAVDATPQERSQGVFCCGPSPLTAIRK 373

Query: 421 GHVCFQFDAPFVFAEVNSD-LIYITAKKDG---THVVENVDATHIGKLIVTKQIGGDGMM 476
           G +   +D  FVF+EVN D LI++    +G    HV+ +++ T IGK I TK +G D   
Sbjct: 374 GDIFIVYDTRFVFSEVNGDRLIWLVKMVNGQEELHVI-SMETTSIGKNISTKAVGQDRRR 432

Query: 477 DITDTYKFQEGQEEERLALETALMYGAKKPLNTEGVMKSRSNVDMDFEVENAVLGKDFKL 536
           DIT  YK+ EG  EER  ++ A +  + +  +   V    + + M  + ++ +LG     
Sbjct: 433 DITYEYKYPEGSSEERQVMDHAFLLLSSEREHRRPV--KENFLHMSVQSDDVLLGNSVNF 490

Query: 537 SITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVL-IQAGEY 595
           ++  +  +     +    S  +  YTG  K   K    + T +      E  L + +  Y
Sbjct: 491 TVILKRKTAALQNVNILGSFELQLYTG--KKMAKLCDLNKTSQIQGQVSEVTLTLDSKTY 548

Query: 596 MGQLL---EQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVTVE 652
           +  L    ++  +  F+ A I E+++++A +  T    PE  I++  T  +G  +     
Sbjct: 549 INSLAILDDEPVIRGFIIAEIVESKEIMASEVFTSFQYPEFSIELPNTGRIGQLLVCNCI 608

Query: 653 FTNPLKETLRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSS 712
           F N L   L +V   L+  G++         ++P  T+Q +  C P  +G +K I  +SS
Sbjct: 609 FKNTLAIPLTDVKFSLESLGISSLQTSDHGTVQPGETIQSQIKCTPIKTGPKKFIVKLSS 668

Query: 713 DSLRHVYGELDVQIQR 728
             ++ +  +  V I +
Sbjct: 669 KQVKEINAQKIVLITK 684


>gi|39777599 transglutaminase 2 isoform b [Homo sapiens]
          Length = 548

 Score =  392 bits (1006), Expect = e-109
 Identities = 225/538 (41%), Positives = 301/538 (55%), Gaps = 24/538 (4%)

Query: 59  DTNKVDHHTDKYENNKLIVRRGQSFYVQIDFS-RPYDPRRDLFRVEYVIGRYPQENKGTY 117
           +TN  DHHT      KL+VRRGQ F++ + F  R Y+   D      V G  P +  GT 
Sbjct: 15  ETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFSVVTGPAPSQEAGTK 74

Query: 118 IPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNP 177
              P+   ++ G W A +V ++D ++ L + +     +G +R+ +   T Y   + S   
Sbjct: 75  ARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLEASTGY---QGSSFV 131

Query: 178 ETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILD 237
                +LFN WC  DAVYLD+E+ER+EYVL   G I+ G    IK   W++GQFEDGILD
Sbjct: 132 LGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPWNFGQFEDGILD 191

Query: 238 TCLYVMD-------RAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPP 290
            CL ++D        A  D S R +P+ V RV S MVN  DD+GVL+G WDN Y  GV P
Sbjct: 192 ICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGRWDNNYGDGVSP 251

Query: 291 SAWTGSVDILLEYRSSE-NPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANL 349
            +W GSVDIL  +++     V+YGQCWVFA V  T LRCLGIP R+VTNY SAHD ++NL
Sbjct: 252 MSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQNSNL 311

Query: 350 QMDIFLEEDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYR 409
            ++ F  E G +    + + +WN+HCW E+WMTRPDL  G+ GWQA+D TPQE S+G Y 
Sbjct: 312 LIEYFRNEFGEIQGDKS-EMIWNFHCWVESWMTRPDLQPGYEGWQALDPTPQEKSEGTYC 370

Query: 410 CGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYITAKKDGTHVVENVDATHIGKLIVTKQ 469
           CGP  V+AIK G +  ++DAPFVFAEVN+D++    + DG+       +  +G  I TK 
Sbjct: 371 CGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSLIVGLKISTKS 430

Query: 470 IGGDGMMDITDTYKFQEGQEEERLALETA--LMYGAKKPLNTEGVMKSRSNVDMDFEVEN 527
           +G D   DIT TYK+ EG  EER A   A  L   A+K   T   M+ R    M+     
Sbjct: 431 VGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKE-ETGMAMRIRVGQSMN----- 484

Query: 528 AVLGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEF-KKETFDVTLEPLSFK 584
             +G DF +     NN+   Y     L A    Y G+   E   K   ++ LEP S K
Sbjct: 485 --MGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSGK 540


>gi|16445035 transglutaminase 7 [Homo sapiens]
          Length = 710

 Score =  363 bits (931), Expect = e-100
 Identities = 228/706 (32%), Positives = 355/706 (50%), Gaps = 37/706 (5%)

Query: 46  LNVTSVHLFKERWDTNKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYV 105
           L + SV L   R   N  +HHT +    +L VRRGQ FY+++ FSRP+  + D       
Sbjct: 7   LRLESVDLQSSR---NNKEHHTQEMGVKRLTVRRGQPFYLRLSFSRPFQSQNDHITFVAE 63

Query: 106 IGRYPQENKGTYIPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVW 165
            G  P E  GT     +        W A     +  S+++S+ +    ++G + + + + 
Sbjct: 64  TGPKPSELLGTRATFFLTRVQPGNVWSASDFTIDSNSLQVSLFTPANAVIGHYTLKIEIS 123

Query: 166 TPYGVLRTSRNPETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRS 225
              G   +   P     +LFNPW  +D VYL +E   +EY++ D G ++ G    I +  
Sbjct: 124 QGQG--HSVTYPLGTFILLFNPWSPEDDVYLPSEILLQEYIMRDYGFVYKGHERFITSWP 181

Query: 226 WSYGQFEDGILDTC-------LYVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVG 278
           W+YGQFE+ I+D C       LY +     D S R + + V RV SAM+N+ DD GVL G
Sbjct: 182 WNYGQFEEDIIDICFEILNKSLYHLKNPAKDCSQRNDVVYVCRVVSAMINSNDDNGVLQG 241

Query: 279 SWDNIYAYGVPPSAWTGSVDILLEYRS-SENPVRYGQCWVFAGVFNTFLRCLGIPARIVT 337
           +W   Y+ GV P  W GSV IL ++ +    PV+YGQCWVFA V  T +RCLG+P R+V+
Sbjct: 242 NWGEDYSKGVSPLEWKGSVAILQQWSARGGQPVKYGQCWVFASVMCTVMRCLGVPTRVVS 301

Query: 338 NYFSAHDNDANLQMDIFLEEDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVD 397
           N+ SAH+ D NL +D + + +  + S   +D +WN+H WNE WM R DLP G+ GWQ +D
Sbjct: 302 NFRSAHNVDRNLTIDTYYDRNAEMLSTQKRDKIWNFHVWNECWMIRKDLPPGYNGWQVLD 361

Query: 398 STPQENSDGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSD-LIYITAKKDGTHVVENV 456
            TPQ+ S G++ CGPASV+AI+ G V   +D PFV+AEVN+D +I++        ++ + 
Sbjct: 362 PTPQQTSSGLFCCGPASVKAIREGDVHLAYDTPFVYAEVNADEVIWLLGDGQAQEILAH- 420

Query: 457 DATHIGKLIVTKQIGGDGMMDITDTYKFQEGQEEERLALETA--LMYGAKKP-------L 507
           + + IGK I TK +G D    IT +YK+ EG  EER     A   M G ++        L
Sbjct: 421 NTSSIGKEISTKMVGSDQRQSITSSYKYPEGSPEERAVFMKASRKMLGPQRASLPFLDLL 480

Query: 508 NTEGVMKSRSNVDMDFEVENAVLGKDFKLSITFR---NNSHNRYTI--TAYLSANITFYT 562
            + G+    + + +         G+D +L +  +   +++H R  I       A    + 
Sbjct: 481 ESGGLRDQPAQLQLHL-ARIPEWGQDLQLLLRIQRVPDSTHPRGPIGLVVRFCAQALLHG 539

Query: 563 GVPKAEFKKETFDVTLEPLSFKKEA---VLIQAGEYMGQLLEQASLHFFVTARINETRDV 619
           G  +  F + T  + L+   F KE    +L+    Y  +L ++  +     A + ET   
Sbjct: 540 GGTQKPFWRHTVRMNLD---FGKETQWPLLLPYSNYRNKLTDEKLIRVSGIAEVEETGRS 596

Query: 620 LAKQKSTVLTIPEIIIKVRGTQVVGSDMTVTVEFTNPLKETLRNVWVHLDGPG-VTRPMK 678
           +   K   L  P + I+V     VG  + V V  TN L   L +  + L+G G +   + 
Sbjct: 597 MLVLKDICLEPPHLSIEVSERAEVGKALRVHVTLTNTLMVALSSCTMVLEGSGLINGQIA 656

Query: 679 KMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYGELDV 724
           K    +    T+Q +    P  +G R+L   +SS+ ++ + G  D+
Sbjct: 657 KDLGTLVAGHTLQIQLDLYPTKAGPRQLQVLISSNEVKEIKGYKDI 702


>gi|4759230 transglutaminase 5 isoform 2 [Homo sapiens]
          Length = 638

 Score =  359 bits (921), Expect = 6e-99
 Identities = 204/572 (35%), Positives = 305/572 (53%), Gaps = 37/572 (6%)

Query: 191 DDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCLYVMDRA---- 246
           +DAVYLD+E +R+EYV+ND G I+ G  N I+   W+YGQFED I+D CL ++D++    
Sbjct: 64  EDAVYLDSEPQRQEYVMNDYGFIYQGSKNWIRPCPWNYGQFEDKIIDICLKLLDKSLHFQ 123

Query: 247 ---QMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDILLEY 303
                D + RG+P+ VSRV  AM+N+ DD GVL G+W   Y  G  P+ WTGSV IL ++
Sbjct: 124 TDPATDCALRGSPVYVSRVVCAMINSNDDNGVLNGNWSENYTDGANPAEWTGSVAILKQW 183

Query: 304 RSSE-NPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLEEDGNVN 362
            ++   PVRYGQCWVFA V  T +RCLGIP R++TN+ S HD D NL +D + +  G + 
Sbjct: 184 NATGCQPVRYGQCWVFAAVMCTVMRCLGIPTRVITNFDSGHDTDGNLIIDEYYDNTGRIL 243

Query: 363 SKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKHGH 422
               KD++WN+H WNE WM R DLP  +GGWQ +D+TPQE S+G+Y CGPASV+AIK G 
Sbjct: 244 GNKKKDTIWNFHVWNECWMARKDLPPAYGGWQVLDATPQEMSNGVYCCGPASVRAIKEGE 303

Query: 423 VCFQFDAPFVFAEVNSDLIYITAKKDGTHVVENVDATHIGKLIVTKQIGGDGMMDITDTY 482
           V   +D PFVF+ VN+D +    +  G     + D + +G  I TK I  D   DIT+ Y
Sbjct: 304 VDLNYDTPFVFSMVNADCMSWLVQ-GGKEQKLHQDTSSVGNFISTKSIQSDERDDITENY 362

Query: 483 KFQEGQEEERLAL-------------------------ETALMYGAKKPLNTEGVMKSRS 517
           K++EG  +ER                             T+L   + + L+T  +  S  
Sbjct: 363 KYEEGSLQERQVFLKALQKLKARSFHGSQRGAELQPSRPTSLSQDSPRSLHTPSLRPSDV 422

Query: 518 -NVDMDFEV-ENAVLGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFD 575
             V + F++ +   +G+D    +   N S     +   LSA    + G P + F ++T  
Sbjct: 423 VQVSLKFKLLDPPNMGQDICFVLLALNMSSQFKDLKVNLSAQSLLHDGSPLSPFWQDTAF 482

Query: 576 VTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIII 635
           +TL P   K     I   +Y   L     +          + + +   K   L+ P I I
Sbjct: 483 ITLSPKEAKTYPCKISYSQYSQYLSTDKLIRISALGEEKSSPEKILVNKIITLSYPSITI 542

Query: 636 KVRGTQVVGSDMTVTVEFTNPLKETLRNVWVHLDGPGVTRPMKKMFREI-RPNSTVQWEE 694
            V G  VV   +++ V F+NPL E + +  + ++G G+ +  +K+F  + +P        
Sbjct: 543 NVLGAAVVNQPLSIQVIFSNPLSEQVEDCVLTVEGSGLFKKQQKVFLGVLKPQHQASIIL 602

Query: 695 VCRPWVSGHRKLIASMSSDSLRHVYGELDVQI 726
              P+ SG R++ A+M S+  + + G  +V +
Sbjct: 603 ETVPFKSGQRQIQANMRSNKFKDIKGYRNVYV 634



 Score = 33.1 bits (74), Expect = 0.94
 Identities = 19/46 (41%), Positives = 29/46 (63%), Gaps = 3/46 (6%)

Query: 61  NKVDHHTDKYENNKLIVRRGQSFYVQIDF-SRPYDPRRD--LFRVE 103
           N V HHT++   + L+VRRGQ+F + + F +R + P  D  +F VE
Sbjct: 17  NNVRHHTEEITVDHLLVRRGQAFNLTLYFRNRSFQPGLDNIIFVVE 62


>gi|166362737 erythrocyte membrane protein band 4.2 isoform 2 [Homo
           sapiens]
          Length = 691

 Score =  236 bits (602), Expect = 6e-62
 Identities = 172/643 (26%), Positives = 291/643 (45%), Gaps = 24/643 (3%)

Query: 61  NKVDHHTDKYENNKLIVRRGQSFYVQIDFSRP---YDPRRDLFRVEYVIGRYPQENKGTY 117
           N  +HHT    + +L VRRGQ F + + F  P   + P      +    G  P +   T 
Sbjct: 17  NNEEHHTKALSSRRLFVRRGQPFTIILYFRAPVRAFLPALKKVALTAQTGEQPSKINRTQ 76

Query: 118 IPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNP 177
              PI S      W A +  R+ +S  +S+ +    ++G + + + V     +L      
Sbjct: 77  ATFPISSLGDRKWWSAVVEERDAQSWTISVTTPADAVIGHYSLLLQVSGRKQLLLGQFT- 135

Query: 178 ETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILD 237
                +LFNPW  +DAV+L NE +R EY+LN  G+I+ G  + I+  SW +GQFE  ++D
Sbjct: 136 -----LLFNPWNREDAVFLKNEAQRMEYLLNQNGLIYLGTADCIQAESWDFGQFEGDVID 190

Query: 238 TCLYVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSV 297
             L ++ + +  +     P+ V+RV  A+++   ++ VL          G   +   GSV
Sbjct: 191 LSLRLLSKDKQ-VEKWSQPVHVARVLGALLHFLKEQRVLPTPQTQATQEGALLNKRRGSV 249

Query: 298 DILLEYRSSEN-PVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLE 356
            IL ++ +    PV  GQ WV A V  T LRCLGIPAR+VT + SA      L +D +  
Sbjct: 250 PILRQWLTGRGRPVYDGQAWVLAAVACTVLRCLGIPARVVTTFASAQGTGGRLLIDEYYN 309

Query: 357 EDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQ 416
           E+G  N +  +  +W +    E WMTRP LP G+ GWQ +  +       +  C    V+
Sbjct: 310 EEGLQNGEGQRGRIWIFQTSTECWMTRPALPQGYDGWQILHPSAPNGGGVLGSCDLVPVR 369

Query: 417 AIKHGHVCFQFDAPFVFAEVNSDLIYITAKKDGTHVVENVDATHIGKLIVTKQIGGDGMM 476
           A+K G +        +FA +N+  +     +DGT  + + +  ++G  I TK +G D   
Sbjct: 370 AVKEGTLGLTPAVSDLFAAINASCVVWKCCEDGTLELTDSNTKYVGNNISTKGVGSDRCE 429

Query: 477 DITDTYKFQEGQEEERLALETALMYGAKKPLNTE---GV----MKSRSNVDMDFEVENAV 529
           DIT  YK+ EG  +E+  LE       K+ +  E   G+    +++ S + +  +  +++
Sbjct: 430 DITQNYKYPEGSLQEKEVLERV----EKEKMEREKDNGIRPPSLETASPLYLLLKAPSSL 485

Query: 530 -LGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAV 588
            L  D ++S+T  N+S     +   +      Y GV  A+  ++   +TL     K   +
Sbjct: 486 PLRGDAQISVTLVNHSEQEKAVQLAIGVQAVHYNGVLAAKLWRKKLHLTLSANLEKIITI 545

Query: 589 LIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMT 648
            +    +     E   L     A  +E+      Q+   +  P + IK+         +T
Sbjct: 546 GLFFSNFERNPPENTFLRLTAMATHSESNLSCFAQEDIAICRPHLAIKMPEKAEQYQPLT 605

Query: 649 VTVEFTNPLKETLRNVWVHLDGPG-VTRPMKKMFREIRPNSTV 690
            +V   N L   + +  + + G G + R     FR + P +T+
Sbjct: 606 ASVSLQNSLDAPMEDCVISILGRGLIHRERSYRFRSVWPENTM 648


>gi|166362735 erythrocyte membrane protein band 4.2 isoform 1 [Homo
           sapiens]
          Length = 721

 Score =  236 bits (602), Expect = 6e-62
 Identities = 172/643 (26%), Positives = 291/643 (45%), Gaps = 24/643 (3%)

Query: 61  NKVDHHTDKYENNKLIVRRGQSFYVQIDFSRP---YDPRRDLFRVEYVIGRYPQENKGTY 117
           N  +HHT    + +L VRRGQ F + + F  P   + P      +    G  P +   T 
Sbjct: 47  NNEEHHTKALSSRRLFVRRGQPFTIILYFRAPVRAFLPALKKVALTAQTGEQPSKINRTQ 106

Query: 118 IPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNP 177
              PI S      W A +  R+ +S  +S+ +    ++G + + + V     +L      
Sbjct: 107 ATFPISSLGDRKWWSAVVEERDAQSWTISVTTPADAVIGHYSLLLQVSGRKQLLLGQFT- 165

Query: 178 ETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILD 237
                +LFNPW  +DAV+L NE +R EY+LN  G+I+ G  + I+  SW +GQFE  ++D
Sbjct: 166 -----LLFNPWNREDAVFLKNEAQRMEYLLNQNGLIYLGTADCIQAESWDFGQFEGDVID 220

Query: 238 TCLYVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSV 297
             L ++ + +  +     P+ V+RV  A+++   ++ VL          G   +   GSV
Sbjct: 221 LSLRLLSKDKQ-VEKWSQPVHVARVLGALLHFLKEQRVLPTPQTQATQEGALLNKRRGSV 279

Query: 298 DILLEYRSSEN-PVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLE 356
            IL ++ +    PV  GQ WV A V  T LRCLGIPAR+VT + SA      L +D +  
Sbjct: 280 PILRQWLTGRGRPVYDGQAWVLAAVACTVLRCLGIPARVVTTFASAQGTGGRLLIDEYYN 339

Query: 357 EDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQ 416
           E+G  N +  +  +W +    E WMTRP LP G+ GWQ +  +       +  C    V+
Sbjct: 340 EEGLQNGEGQRGRIWIFQTSTECWMTRPALPQGYDGWQILHPSAPNGGGVLGSCDLVPVR 399

Query: 417 AIKHGHVCFQFDAPFVFAEVNSDLIYITAKKDGTHVVENVDATHIGKLIVTKQIGGDGMM 476
           A+K G +        +FA +N+  +     +DGT  + + +  ++G  I TK +G D   
Sbjct: 400 AVKEGTLGLTPAVSDLFAAINASCVVWKCCEDGTLELTDSNTKYVGNNISTKGVGSDRCE 459

Query: 477 DITDTYKFQEGQEEERLALETALMYGAKKPLNTE---GV----MKSRSNVDMDFEVENAV 529
           DIT  YK+ EG  +E+  LE       K+ +  E   G+    +++ S + +  +  +++
Sbjct: 460 DITQNYKYPEGSLQEKEVLERV----EKEKMEREKDNGIRPPSLETASPLYLLLKAPSSL 515

Query: 530 -LGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAV 588
            L  D ++S+T  N+S     +   +      Y GV  A+  ++   +TL     K   +
Sbjct: 516 PLRGDAQISVTLVNHSEQEKAVQLAIGVQAVHYNGVLAAKLWRKKLHLTLSANLEKIITI 575

Query: 589 LIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMT 648
            +    +     E   L     A  +E+      Q+   +  P + IK+         +T
Sbjct: 576 GLFFSNFERNPPENTFLRLTAMATHSESNLSCFAQEDIAICRPHLAIKMPEKAEQYQPLT 635

Query: 649 VTVEFTNPLKETLRNVWVHLDGPG-VTRPMKKMFREIRPNSTV 690
            +V   N L   + +  + + G G + R     FR + P +T+
Sbjct: 636 ASVSLQNSLDAPMEDCVISILGRGLIHRERSYRFRSVWPENTM 678


>gi|4506339 peroxisomal biogenesis factor 19 isoform a [Homo
           sapiens]
          Length = 299

 Score = 30.0 bits (66), Expect = 8.0
 Identities = 23/77 (29%), Positives = 40/77 (51%), Gaps = 3/77 (3%)

Query: 585 KEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVG 644
           K+A+     ++  +L + + L    TA   +    LA+++  ++   + + +  G   VG
Sbjct: 60  KDALFASQEKFFQELFD-SELASQATAEFEKAMKELAEEEPHLVEQFQKLSEAAGR--VG 116

Query: 645 SDMTVTVEFTNPLKETL 661
           SDMT   EFT+ LKETL
Sbjct: 117 SDMTSQQEFTSCLKETL 133


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,437,757
Number of Sequences: 37866
Number of extensions: 1220837
Number of successful extensions: 2304
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 2232
Number of HSP's gapped (non-prelim): 17
length of query: 732
length of database: 18,247,518
effective HSP length: 110
effective length of query: 622
effective length of database: 14,082,258
effective search space: 8759164476
effective search space used: 8759164476
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.