Guide to the Human Genome
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Search of human proteins with 239755981

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239755981 PREDICTED: hypothetical protein XP_002344766 [Homo
sapiens]
         (307 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239755981 PREDICTED: hypothetical protein XP_002344766 [Homo ...   632   0.0  
gi|239750506 PREDICTED: hypothetical protein XP_002347417 [Homo ...   613   e-176
gi|239744803 PREDICTED: hypothetical protein XP_002343287 [Homo ...   613   e-176
gi|157671951 solute carrier family 4, anion exchanger, member 3 ...    55   6e-08
gi|13376335 hypothetical protein LOC79946 [Homo sapiens]               51   1e-06
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]         50   2e-06
gi|119395716 forkhead box C1 [Homo sapiens]                            50   2e-06
gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens]    50   3e-06
gi|239750121 PREDICTED: hypothetical protein XP_002347280 [Homo ...    48   1e-05
gi|126090909 engrailed homeobox 1 [Homo sapiens]                       47   2e-05
gi|157671953 solute carrier family 4, anion exchanger, member 3 ...    47   2e-05
gi|33457350 OTU domain containing 5 isoform a [Homo sapiens]           47   3e-05
gi|209977021 OTU domain containing 5 isoform b [Homo sapiens]          47   3e-05
gi|209977019 OTU domain containing 5 isoform b [Homo sapiens]          47   3e-05
gi|21361699 sphingosine kinase 2 [Homo sapiens]                        46   4e-05
gi|239748777 PREDICTED: hypothetical protein [Homo sapiens]            46   4e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni...    46   4e-05
gi|239755634 PREDICTED: hypothetical protein [Homo sapiens]            46   5e-05
gi|239744429 PREDICTED: hypothetical protein XP_002343157 [Homo ...    46   5e-05
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      45   8e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    45   8e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    45   8e-05
gi|40255272 xin actin-binding repeat containing 1 [Homo sapiens]       45   8e-05
gi|239754674 PREDICTED: hypothetical protein [Homo sapiens]            45   1e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    45   1e-04
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]            44   1e-04
gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens]    44   2e-04
gi|33286436 gametogenetin [Homo sapiens]                               44   2e-04
gi|169213235 PREDICTED: hypothetical protein [Homo sapiens]            43   3e-04
gi|169212744 PREDICTED: hypothetical protein [Homo sapiens]            43   3e-04

>gi|239755981 PREDICTED: hypothetical protein XP_002344766 [Homo
           sapiens]
          Length = 307

 Score =  632 bits (1629), Expect = 0.0
 Identities = 307/307 (100%), Positives = 307/307 (100%)

Query: 1   MPNLLYEWTRKTHVPANPAPFHTPRKRHPLSHTPHATAHPPSSPPPLHITPVLPPTFPGT 60
           MPNLLYEWTRKTHVPANPAPFHTPRKRHPLSHTPHATAHPPSSPPPLHITPVLPPTFPGT
Sbjct: 1   MPNLLYEWTRKTHVPANPAPFHTPRKRHPLSHTPHATAHPPSSPPPLHITPVLPPTFPGT 60

Query: 61  QPPRALRLAEGSGEGKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVGSRASSGPGLPS 120
           QPPRALRLAEGSGEGKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVGSRASSGPGLPS
Sbjct: 61  QPPRALRLAEGSGEGKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVGSRASSGPGLPS 120

Query: 121 AAAARPARKTLTCQPRSIESPATASSAGCGSGPRVPQVRLLGPGGRPSSPARDGSRRKAG 180
           AAAARPARKTLTCQPRSIESPATASSAGCGSGPRVPQVRLLGPGGRPSSPARDGSRRKAG
Sbjct: 121 AAAARPARKTLTCQPRSIESPATASSAGCGSGPRVPQVRLLGPGGRPSSPARDGSRRKAG 180

Query: 181 HGCTSQSQGDAVAMEAEARGSPGGRVLMQELTLLPVEASLILSVVAAVLQLHSYRRPAGD 240
           HGCTSQSQGDAVAMEAEARGSPGGRVLMQELTLLPVEASLILSVVAAVLQLHSYRRPAGD
Sbjct: 181 HGCTSQSQGDAVAMEAEARGSPGGRVLMQELTLLPVEASLILSVVAAVLQLHSYRRPAGD 240

Query: 241 TPDPRRGHHRHRRRQRGGGRGGGGRGGREAAATVHGNAAASSSAAARGAAAATTIDGGGK 300
           TPDPRRGHHRHRRRQRGGGRGGGGRGGREAAATVHGNAAASSSAAARGAAAATTIDGGGK
Sbjct: 241 TPDPRRGHHRHRRRQRGGGRGGGGRGGREAAATVHGNAAASSSAAARGAAAATTIDGGGK 300

Query: 301 EDAAGAG 307
           EDAAGAG
Sbjct: 301 EDAAGAG 307


>gi|239750506 PREDICTED: hypothetical protein XP_002347417 [Homo
           sapiens]
          Length = 325

 Score =  613 bits (1580), Expect = e-176
 Identities = 299/299 (100%), Positives = 299/299 (100%)

Query: 9   TRKTHVPANPAPFHTPRKRHPLSHTPHATAHPPSSPPPLHITPVLPPTFPGTQPPRALRL 68
           TRKTHVPANPAPFHTPRKRHPLSHTPHATAHPPSSPPPLHITPVLPPTFPGTQPPRALRL
Sbjct: 27  TRKTHVPANPAPFHTPRKRHPLSHTPHATAHPPSSPPPLHITPVLPPTFPGTQPPRALRL 86

Query: 69  AEGSGEGKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVGSRASSGPGLPSAAAARPAR 128
           AEGSGEGKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVGSRASSGPGLPSAAAARPAR
Sbjct: 87  AEGSGEGKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVGSRASSGPGLPSAAAARPAR 146

Query: 129 KTLTCQPRSIESPATASSAGCGSGPRVPQVRLLGPGGRPSSPARDGSRRKAGHGCTSQSQ 188
           KTLTCQPRSIESPATASSAGCGSGPRVPQVRLLGPGGRPSSPARDGSRRKAGHGCTSQSQ
Sbjct: 147 KTLTCQPRSIESPATASSAGCGSGPRVPQVRLLGPGGRPSSPARDGSRRKAGHGCTSQSQ 206

Query: 189 GDAVAMEAEARGSPGGRVLMQELTLLPVEASLILSVVAAVLQLHSYRRPAGDTPDPRRGH 248
           GDAVAMEAEARGSPGGRVLMQELTLLPVEASLILSVVAAVLQLHSYRRPAGDTPDPRRGH
Sbjct: 207 GDAVAMEAEARGSPGGRVLMQELTLLPVEASLILSVVAAVLQLHSYRRPAGDTPDPRRGH 266

Query: 249 HRHRRRQRGGGRGGGGRGGREAAATVHGNAAASSSAAARGAAAATTIDGGGKEDAAGAG 307
           HRHRRRQRGGGRGGGGRGGREAAATVHGNAAASSSAAARGAAAATTIDGGGKEDAAGAG
Sbjct: 267 HRHRRRQRGGGRGGGGRGGREAAATVHGNAAASSSAAARGAAAATTIDGGGKEDAAGAG 325


>gi|239744803 PREDICTED: hypothetical protein XP_002343287 [Homo
           sapiens]
          Length = 325

 Score =  613 bits (1580), Expect = e-176
 Identities = 299/299 (100%), Positives = 299/299 (100%)

Query: 9   TRKTHVPANPAPFHTPRKRHPLSHTPHATAHPPSSPPPLHITPVLPPTFPGTQPPRALRL 68
           TRKTHVPANPAPFHTPRKRHPLSHTPHATAHPPSSPPPLHITPVLPPTFPGTQPPRALRL
Sbjct: 27  TRKTHVPANPAPFHTPRKRHPLSHTPHATAHPPSSPPPLHITPVLPPTFPGTQPPRALRL 86

Query: 69  AEGSGEGKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVGSRASSGPGLPSAAAARPAR 128
           AEGSGEGKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVGSRASSGPGLPSAAAARPAR
Sbjct: 87  AEGSGEGKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVGSRASSGPGLPSAAAARPAR 146

Query: 129 KTLTCQPRSIESPATASSAGCGSGPRVPQVRLLGPGGRPSSPARDGSRRKAGHGCTSQSQ 188
           KTLTCQPRSIESPATASSAGCGSGPRVPQVRLLGPGGRPSSPARDGSRRKAGHGCTSQSQ
Sbjct: 147 KTLTCQPRSIESPATASSAGCGSGPRVPQVRLLGPGGRPSSPARDGSRRKAGHGCTSQSQ 206

Query: 189 GDAVAMEAEARGSPGGRVLMQELTLLPVEASLILSVVAAVLQLHSYRRPAGDTPDPRRGH 248
           GDAVAMEAEARGSPGGRVLMQELTLLPVEASLILSVVAAVLQLHSYRRPAGDTPDPRRGH
Sbjct: 207 GDAVAMEAEARGSPGGRVLMQELTLLPVEASLILSVVAAVLQLHSYRRPAGDTPDPRRGH 266

Query: 249 HRHRRRQRGGGRGGGGRGGREAAATVHGNAAASSSAAARGAAAATTIDGGGKEDAAGAG 307
           HRHRRRQRGGGRGGGGRGGREAAATVHGNAAASSSAAARGAAAATTIDGGGKEDAAGAG
Sbjct: 267 HRHRRRQRGGGRGGGGRGGREAAATVHGNAAASSSAAARGAAAATTIDGGGKEDAAGAG 325


>gi|157671951 solute carrier family 4, anion exchanger, member 3
           isoform 1 [Homo sapiens]
          Length = 1232

 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 70/266 (26%), Positives = 98/266 (36%), Gaps = 47/266 (17%)

Query: 15  PANPAPFHTPRKRHPLSHTPHATAHPPSSP-PPLHITPVLPPTFP--------------- 58
           P  P+  ++ R      HT H T HP S+  PP H    LPPT                 
Sbjct: 59  PEKPSRSYSERDFEFHRHTSHHTHHPLSARLPPPHKLRRLPPTSARHTRRKRKKEKTSAP 118

Query: 59  ---GTQPPRALRLAEGSGEGKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVGSRASSG 115
              GT P +    A    E ++EE    ++   P+ PP     G        +GS     
Sbjct: 119 PSEGTPPIQEEGGAGVDEEEEEEEEEEGESEAEPVEPP---PSGTPQKAKFSIGSDEDDS 175

Query: 116 PGLPSAAAARPARKTLTCQPRSIESPATASSAGCGSGPRVPQVRLLGPGGRPSSPARDGS 175
           PGLP  AA    +   +  P + +SP  +SS+     PR    RL G   RP SP+    
Sbjct: 176 PGLPGRAAV--TKPLPSVGPHTDKSPQHSSSS---PSPRARASRLAGEKSRPWSPSASYD 230

Query: 176 RRKAGHGCTSQSQGDAVAMEAEARGSPGGRVLMQELTLLPVEASLILSVVAAVLQLHSYR 235
            R+                   A G+PGG    Q++     EA ++ S     ++ H   
Sbjct: 231 LRER-------------LCPGSALGNPGGP--EQQVPTDEAEAQMLGSADLDDMKSHRLE 275

Query: 236 RPAGDTPDPRRGHHRHRRRQRGGGRG 261
               D P  RR H   +  +  GGRG
Sbjct: 276 ----DNPGVRR-HLVKKPSRTQGGRG 296


>gi|13376335 hypothetical protein LOC79946 [Homo sapiens]
          Length = 257

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 48/167 (28%), Positives = 65/167 (38%), Gaps = 21/167 (12%)

Query: 16  ANPAPFHTPRKRHPLSHTPHATAHPPSSPPPLHITPVLPPTFPGTQPPRALRLAEGSGEG 75
           A+ AP   PR R P       T  P + P P           P ++  R  R       G
Sbjct: 106 ASTAPPRHPRPRRPGGPALRPTPRPCAGPAPP----------PASRDCRCRRPRRWPRAG 155

Query: 76  KQEEGRRAQA-RPRPLRPPWEVRGGA----RGPCSAPVGSRASSGPGLPSAAAARPARKT 130
           ++  GRRA A +P      W  RG      R  C+   G+R +  P  P+ A+   A  +
Sbjct: 156 RR--GRRAGACKPSCAGAAWSARGAPLCSYRTSCAGSCGARTAPTPA-PTCASPSAAASS 212

Query: 131 LTCQPRSIESPATASSAGCGSGPRVPQVRLLGPGGRPSSPARDGSRR 177
              + R+  SP TA S  CG+GP           G+P S A  G  R
Sbjct: 213 CCRRRRACSSPTTAWSGACGAGPTAATA---AQPGKPRSAAAPGRAR 256


>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
          Length = 1682

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 49/146 (33%), Positives = 63/146 (43%), Gaps = 13/146 (8%)

Query: 33  TPHATAHP-PSSPPPLHITPVL-PPTFPGTQPPRALRLAEGSGEGKQEEGRRAQARPRPL 90
           TPH +  P PSSPPP     +L PP  P      A R A   GE  +E     +  PRP 
Sbjct: 456 TPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPA 515

Query: 91  RPPWEVRGGARGPCSA--PVGSRASSGPGLPSAAAARPARKTLTCQPRSIESPATASSAG 148
            PP   R G  GP ++   VG++ S  P  P            T    S     ++S AG
Sbjct: 516 PPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPT--------TSSSNSNSGSHSSSPAG 567

Query: 149 CGSGPRVPQV-RLLGPGGRPSSPARD 173
             S P  P + R + P  RP SPA++
Sbjct: 568 PVSFPPPPYLARSIDPLPRPPSPAQN 593



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 60/266 (22%), Positives = 84/266 (31%), Gaps = 35/266 (13%)

Query: 40   PPSSPPPLHITPVLPPTFPGTQPP----------RALRLAEGSGEGKQEEGRRAQARPRP 89
            PP+ PPP  +    PP+ P   PP              + EG     +  G     RP P
Sbjct: 772  PPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGP 831

Query: 90   LRPPWEVRGGARGPCSAPVGSRASSGPGLPSAAAARPARKTLTCQPRSIESPATASSAGC 149
            L       G   G  + P  S A S  G P  +A+  ++ + +  P + E  A       
Sbjct: 832  LPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPG 891

Query: 150  GSGPRVPQVRLLGPGGRPSSPARDGSRR-------KAGHGCTSQSQGDAVAMEAEARGSP 202
               P  P   L  P  R  S   +   R       + G   T  +     A  A++    
Sbjct: 892  PMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSG--- 948

Query: 203  GGRVLMQELTLLPVEASLILSVVAAVLQLHSYRRPAGDTPDPRRGHHRHRRRQRGGGRGG 262
                   E  L P +A      VAAV         +G     ++ H +  RR R   +  
Sbjct: 949  ------TERLLPPAQAKEEAGGVAAV---------SGSCKRRQKEHQKEHRRHRRACKDS 993

Query: 263  GGRGGREAAATVHGNAAASSSAAARG 288
             GR  RE  A          S    G
Sbjct: 994  VGRRPREGRAKAKAKVPKEKSRRVLG 1019



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 20/52 (38%), Positives = 23/52 (44%), Gaps = 10/52 (19%)

Query: 19  APFHTPRKRHPLSH-----TPHATAHPPSSPPPLHITPVLPPTFPGTQPPRA 65
           AP     +RH L H      P  TAHPP       + P  PP  PG +PP A
Sbjct: 298 APPERQEQRHSLPHPYPYPAPAYTAHPPGH----RLVPAAPPG-PGPRPPGA 344



 Score = 29.3 bits (64), Expect = 4.6
 Identities = 36/125 (28%), Positives = 40/125 (32%), Gaps = 24/125 (19%)

Query: 40  PPSSPPPLHITPVLPPTFPG--TQPPRAL------RLAEGSGEGKQEEGRRAQARPRPLR 91
           PP  PPP    P  PP  PG  T PP  L          G   G + +G     R     
Sbjct: 248 PPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQ---- 303

Query: 92  PPWEVRGGARGPCSAPVGSRASSGPGLPSAAAARPARKTLTCQPRSIESPATASSAGCGS 151
              E R     P   P  +  +  PG     AA P        PR    P  A S GC  
Sbjct: 304 ---EQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGP-----GPR----PPGAESHGCLP 351

Query: 152 GPRVP 156
             R P
Sbjct: 352 ATRPP 356



 Score = 29.3 bits (64), Expect = 4.6
 Identities = 39/133 (29%), Positives = 49/133 (36%), Gaps = 25/133 (18%)

Query: 15  PANPAPFHTP----RKRHPLSHTPHATAHPPSSPPPLHITPVLPPTFPGTQPPRALRLAE 70
           PA P  F  P    R   PL   P + A  P  PP + +T  LPP      PP +     
Sbjct: 565 PAGPVSFPPPPYLARSIDPLPRPP-SPAQNPQDPPLVPLTLALPPA-----PPSSCH-QN 617

Query: 71  GSGEGKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVGSRASSGPGLPSAAAARPARKT 130
            SG  ++ E      RPR   P     G   GP   P G  + +   +P      PAR  
Sbjct: 618 TSGSFRRPE----SPRPRVSFPKTPEVG--PGP---PPGPLSKAPQPVPPGVGELPAR-- 666

Query: 131 LTCQPRSIESPAT 143
               PR  + P T
Sbjct: 667 ---GPRLFDFPPT 676


>gi|119395716 forkhead box C1 [Homo sapiens]
          Length = 553

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 61/212 (28%), Positives = 77/212 (36%), Gaps = 16/212 (7%)

Query: 86  RPRPLRPPWEVRGGARGPCSAPVGSR-------ASSGPGLPSAAAARPARKTLTCQPRSI 138
           R  P  PP +  G A GP   PV  +           P  P + AA     +    P+ I
Sbjct: 199 RQPPPAPPEQADGNAPGPQPPPVRIQDIKTENGTCPSPPQPLSPAAALGSGSAAAVPK-I 257

Query: 139 ESP-ATASSAGCGSGP--RVPQVRLLGPGGRPSSPARDGSRRKAGHGCTSQSQGDAVA-M 194
           ESP +++SS   GS P   +P  R L   G  S+P          H     SQG +V  +
Sbjct: 258 ESPDSSSSSLSSGSSPPGSLPSARPLSLDGADSAPPPPAPSAPPPH----HSQGFSVDNI 313

Query: 195 EAEARGSPGGRVLMQELTLLPVEASLILSVVAAVLQLHSYRRPAGDTPDPRRGHHRHRRR 254
               RGSP          LL   A+   + +A  L L +Y                    
Sbjct: 314 MTSLRGSPQSAAAELSSGLLASAAASSRAGIAPPLALGAYSPGQSSLYSSPCSQTSSAGS 373

Query: 255 QRGGGRGGGGRGGREAAATVHGNAAASSSAAA 286
             GGG G G  GG   A T H N  A S  AA
Sbjct: 374 SGGGGGGAGAAGGAGGAGTYHCNLQAMSLYAA 405


>gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens]
          Length = 753

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 52/171 (30%), Positives = 63/171 (36%), Gaps = 33/171 (19%)

Query: 35  HATAHPPSSPPPLHITPVLPPTFPGTQPPRALRLAEGSGEGKQEEGRRAQARPRPLRPPW 94
           H+  HP S        P +PPT+P   PP A  L+   G             P P  PP 
Sbjct: 309 HSNQHPQS--------PAVPPTYPSGPPPAASALSTTPGN---------NGVPAPAAPP- 350

Query: 95  EVRGGARGPCSAPVGSRASSGPGLPSAAAARPARK-TLTCQPRSIESPATASSAGCGSGP 153
                A GP ++P  S  S  P   + A A PA     T QPR    P+   S G G G 
Sbjct: 351 ----SALGPKASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPR---PPSVQPSGGGGGGS 403

Query: 154 RVPQVRLLGPGGRPSSPARDGSRRKAGHGCTSQSQGDAVAMEAEARGSPGG 204
                   G G   SS +  G      +G TS S   A +    A  S GG
Sbjct: 404 G-------GGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGG 447



 Score = 29.6 bits (65), Expect = 3.5
 Identities = 51/209 (24%), Positives = 70/209 (33%), Gaps = 49/209 (23%)

Query: 15  PANPA-----PFHTPRKRHPLSHTPHATAHPPSSPPPLHITPVLPPT---FPGTQPPRAL 66
           P +PA     P   P     LS TP     P  + PP  + P   P      GT  P A 
Sbjct: 314 PQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQ 373

Query: 67  RLAEGSGEGKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVGSRASSGPGL-------- 118
            +A  +  G        Q RP  ++P     GG+ G  S+   S +S+G G         
Sbjct: 374 AVAPPAPSGPST----TQPRPPSVQPSGGGGGGSGGGGSSS-SSNSSAGGGAGKQNGATS 428

Query: 119 -PSAAAARPARKTLTCQ--------------------PRSIESPATASSAGCG------- 150
             S  A  PA   L+                      P + + P+ A+  G G       
Sbjct: 429 YSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGAGGVAPGSG 488

Query: 151 SGPRVPQVRLLGPGGRPSSPARDGSRRKA 179
           +    P + +  P   PSSP    S  KA
Sbjct: 489 NNSGGPSLLVPLPVNPPSSPTPSFSDAKA 517


>gi|239750121 PREDICTED: hypothetical protein XP_002347280 [Homo
           sapiens]
          Length = 402

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 73/254 (28%), Positives = 99/254 (38%), Gaps = 41/254 (16%)

Query: 82  RAQARPRPLRPPWEVRGGARGPC--SAPVGSRAS-SGPGLPSAAAA----------RPAR 128
           R +A  RP R    VRGG  G C  S   GS A+ SG G+P  + +          +  R
Sbjct: 49  RGRAERRPARGK-HVRGGGVGGCRDSRAGGSHAAPSGLGVPGDSESALGLLEPGPPKSLR 107

Query: 129 KTLTCQPRSIESPATASSAGCGSGP--RVPQV--RLLGPGGRPSSPARDGSRRKAGHGCT 184
            ++T        P+ ASSA  G  P  RVP       G   R  S   DG R ++G GC 
Sbjct: 108 ISVTLGQAPRAGPSAASSAAAGKTPPSRVPAEPSSRRGASKRRESWRTDGERLRSGRGCA 167

Query: 185 SQSQGDAVAMEAEARGSPGGRVL--MQELTLLP-VEASLILSVVAAVLQLHSY------R 235
             ++G   +++    G P   V+   +   L P V  S  LS    + +  S       R
Sbjct: 168 GAARGPDASLDTRREGWPRAAVVGRHEARRLKPGVSVSSSLSPGPPLQRSSSLNETLRGR 227

Query: 236 RPAGDTPDPRRGHHRHRRRQRGGGRGGGGRGGREAAATVHGNAAA-SSSAAARG--AAAA 292
           RP G  P              G  RG     GR+ +A    +A+A  +  AAR      A
Sbjct: 228 RPPGPAP-----------AAAGATRGTAAPPGRDPSAWFLDSASACPTPLAARSWHPFVA 276

Query: 293 TTIDGGGKEDAAGA 306
             + G GK    GA
Sbjct: 277 NKLCGRGKGAGGGA 290


>gi|126090909 engrailed homeobox 1 [Homo sapiens]
          Length = 392

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 60/219 (27%), Positives = 80/219 (36%), Gaps = 43/219 (19%)

Query: 15  PANPAPFHTPRKRHPLSHTPHATAHPPSSPP-----PLH---------------ITPVLP 54
           PA P+P   P    PL+H PH   HPP  PP     P H               I  +L 
Sbjct: 54  PAPPSPPAAPCLP-PLAHHPHLPPHPPPPPPQHLAAPAHQPQPAAQLHRTTNFFIDNILR 112

Query: 55  PTF--PGTQPPRALRLAE-------GSGEGKQEEGRRAQARPRPLRPPWEVRGGARGPCS 105
           P F     QPP  L +A        G G  +++ G+ A  R  P+ P      GA     
Sbjct: 113 PDFGCKKEQPPPQLLVAAAARGGAGGGGRVERDRGQTAAGRD-PVHPLGTRAPGAASLLC 171

Query: 106 APVGSRASSGP--GLPSAAAARPARKTLTCQPRSIESPATASSAGCGSGPRVPQVRLLGP 163
           AP    A+ GP  G   AAA   A K       +  + A  ++A   +  +       G 
Sbjct: 172 AP---DANCGPPDGSQPAAAGAGASKAGNPAAAAAAAAAAVAAAAAAAAAKPSDTGGGGS 228

Query: 164 GGRPSSPARDGSRRKAGHGCTSQSQGDAVAMEAEARGSP 202
           GG   SP   G++    HG        A+ +   A G P
Sbjct: 229 GGGAGSPGAQGTKYPE-HG------NPAILLMGSANGGP 260



 Score = 33.5 bits (75), Expect = 0.24
 Identities = 22/53 (41%), Positives = 25/53 (47%), Gaps = 3/53 (5%)

Query: 255 QRGGGRGGGGRGGREAAATVHGNAAASSSAAARGAAAATTIDGGGKEDAAGAG 307
           Q      G  + G  AAA     AAA++ AAA  AAAA   D GG     GAG
Sbjct: 184 QPAAAGAGASKAGNPAAAAA---AAAAAVAAAAAAAAAKPSDTGGGGSGGGAG 233


>gi|157671953 solute carrier family 4, anion exchanger, member 3
           isoform 2 [Homo sapiens]
          Length = 1259

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 69/288 (23%), Positives = 94/288 (32%), Gaps = 64/288 (22%)

Query: 15  PANPAPFHTPRKRHPLSHTPHATAHPPSSP-PPLHITPVLPPTFP--------------- 58
           P  P+  ++ R      HT H T HP S+  PP H    LPPT                 
Sbjct: 59  PEKPSRSYSERDFEFHRHTSHHTHHPLSARLPPPHKLRRLPPTSARHTRRKRKKEKTSAP 118

Query: 59  ---GTQPPRALRLAEGSGEGKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVGSRASSG 115
              GT P +    A    E ++EE    ++   P+ PP     G        +GS     
Sbjct: 119 PSEGTPPIQEEGGAGVDEEEEEEEEEEGESEAEPVEPP---PSGTPQKAKFSIGSDEDDS 175

Query: 116 PGLPSAAAA-------------RPARKTLTCQ---------PRSIESPATASSAGCGSGP 153
           PGLP  AA               P   +  C            ++ SP           P
Sbjct: 176 PGLPGRAAVTKPLPSVGPHTDKSPQHSSRPCSELRDGDGTTDLALSSPRLLCCLPSSPSP 235

Query: 154 RVPQVRLLGPGGRPSSPARDGSRRKAGHGCTSQSQGDAVAMEAEARGSPGGRVLMQELTL 213
           R    RL G   RP SP+     R+                   A G+PGG    Q++  
Sbjct: 236 RARASRLAGEKSRPWSPSASYDLRER-------------LCPGSALGNPGGP--EQQVPT 280

Query: 214 LPVEASLILSVVAAVLQLHSYRRPAGDTPDPRRGHHRHRRRQRGGGRG 261
              EA ++ S     ++ H       D P  RR H   +  +  GGRG
Sbjct: 281 DEAEAQMLGSADLDDMKSHRLE----DNPGVRR-HLVKKPSRTQGGRG 323


>gi|33457350 OTU domain containing 5 isoform a [Homo sapiens]
          Length = 571

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 69/251 (27%), Positives = 85/251 (33%), Gaps = 65/251 (25%)

Query: 37  TAHPPSSPPPLHITPVLPPTFPGTQPPRALRLAEGSGEGKQEEGRRAQARPRPLRPPWEV 96
           T  P   PPP    P   P  PG  PP A R   G G G    G               V
Sbjct: 2   TILPKKKPPPPDADPANEPPPPGPMPP-APRRGGGVGVGGGGTG---------------V 45

Query: 97  RGGARGPCSAPVGSRASSGPGLPSAAAARPARKTLTCQPRSIESPATASSAGCGSGPRVP 156
            GG R   S  VG+R  + P         P +  L   P ++   A A   G  +GPR P
Sbjct: 46  GGGDRDRDSGVVGARPRASP---------PPQGPLPGPPGALHRWALAVPPGAVAGPR-P 95

Query: 157 QVRLLGPGGRPSSPARDGSRRKAGHGCTSQSQGDAVAMEAEARGSPGGRVLMQELTLLPV 216
           Q     P G P  P         G G      GDA+   A   G+ G             
Sbjct: 96  QQASPPPCGGPGGP---------GGG-----PGDALGAAAAGVGAAG------------- 128

Query: 217 EASLILSVVAAVLQLHSYRRPAGDTPDPRRGHHRHRRRQRGGGRGGGGRGGREAAATVHG 276
              +++ V  AV          G    P  GH + RR+  G G  GGG   RE     + 
Sbjct: 129 ---VVVGVGGAV-------GVGGCCSGP--GHSKRRRQAPGVGAVGGGSPEREEVGAGYN 176

Query: 277 NAAASSSAAAR 287
           +     +AAAR
Sbjct: 177 SEDEYEAAAAR 187


>gi|209977021 OTU domain containing 5 isoform b [Homo sapiens]
          Length = 566

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 69/251 (27%), Positives = 85/251 (33%), Gaps = 65/251 (25%)

Query: 37  TAHPPSSPPPLHITPVLPPTFPGTQPPRALRLAEGSGEGKQEEGRRAQARPRPLRPPWEV 96
           T  P   PPP    P   P  PG  PP A R   G G G    G               V
Sbjct: 2   TILPKKKPPPPDADPANEPPPPGPMPP-APRRGGGVGVGGGGTG---------------V 45

Query: 97  RGGARGPCSAPVGSRASSGPGLPSAAAARPARKTLTCQPRSIESPATASSAGCGSGPRVP 156
            GG R   S  VG+R  + P         P +  L   P ++   A A   G  +GPR P
Sbjct: 46  GGGDRDRDSGVVGARPRASP---------PPQGPLPGPPGALHRWALAVPPGAVAGPR-P 95

Query: 157 QVRLLGPGGRPSSPARDGSRRKAGHGCTSQSQGDAVAMEAEARGSPGGRVLMQELTLLPV 216
           Q     P G P  P         G G      GDA+   A   G+ G             
Sbjct: 96  QQASPPPCGGPGGP---------GGG-----PGDALGAAAAGVGAAG------------- 128

Query: 217 EASLILSVVAAVLQLHSYRRPAGDTPDPRRGHHRHRRRQRGGGRGGGGRGGREAAATVHG 276
              +++ V  AV          G    P  GH + RR+  G G  GGG   RE     + 
Sbjct: 129 ---VVVGVGGAV-------GVGGCCSGP--GHSKRRRQAPGVGAVGGGSPEREEVGAGYN 176

Query: 277 NAAASSSAAAR 287
           +     +AAAR
Sbjct: 177 SEDEYEAAAAR 187


>gi|209977019 OTU domain containing 5 isoform b [Homo sapiens]
          Length = 566

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 69/251 (27%), Positives = 85/251 (33%), Gaps = 65/251 (25%)

Query: 37  TAHPPSSPPPLHITPVLPPTFPGTQPPRALRLAEGSGEGKQEEGRRAQARPRPLRPPWEV 96
           T  P   PPP    P   P  PG  PP A R   G G G    G               V
Sbjct: 2   TILPKKKPPPPDADPANEPPPPGPMPP-APRRGGGVGVGGGGTG---------------V 45

Query: 97  RGGARGPCSAPVGSRASSGPGLPSAAAARPARKTLTCQPRSIESPATASSAGCGSGPRVP 156
            GG R   S  VG+R  + P         P +  L   P ++   A A   G  +GPR P
Sbjct: 46  GGGDRDRDSGVVGARPRASP---------PPQGPLPGPPGALHRWALAVPPGAVAGPR-P 95

Query: 157 QVRLLGPGGRPSSPARDGSRRKAGHGCTSQSQGDAVAMEAEARGSPGGRVLMQELTLLPV 216
           Q     P G P  P         G G      GDA+   A   G+ G             
Sbjct: 96  QQASPPPCGGPGGP---------GGG-----PGDALGAAAAGVGAAG------------- 128

Query: 217 EASLILSVVAAVLQLHSYRRPAGDTPDPRRGHHRHRRRQRGGGRGGGGRGGREAAATVHG 276
              +++ V  AV          G    P  GH + RR+  G G  GGG   RE     + 
Sbjct: 129 ---VVVGVGGAV-------GVGGCCSGP--GHSKRRRQAPGVGAVGGGSPEREEVGAGYN 176

Query: 277 NAAASSSAAAR 287
           +     +AAAR
Sbjct: 177 SEDEYEAAAAR 187


>gi|21361699 sphingosine kinase 2 [Homo sapiens]
          Length = 654

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 46/163 (28%), Positives = 58/163 (35%), Gaps = 25/163 (15%)

Query: 15  PANPAPFHT-PRKRHPLSHTPHATAHPPSSPPPLHIT------PVLPPTFPGTQPPRALR 67
           PA+P P H+ PR +  L+ TP     PP +  PLH +      P+  P       P  L 
Sbjct: 385 PASPTPAHSLPRAKSELTLTPDPA--PPMAHSPLHRSVSDLPLPLPQPALASPGSPEPLP 442

Query: 68  LAEGSGEGKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVGSRASSGPGLPSAAAARPA 127
           +   +G G +  G    A   PL P                    SS PG P AA   P 
Sbjct: 443 ILSLNGGGPELAGDWGGAGDAPLSPD----------------PLLSSPPGSPKAALHSPV 486

Query: 128 RKTLTCQPRSIESPATASSAGCGSGPRVPQVRLLGPGGRPSSP 170
            +     P S   P     A  G+    P   LL P G P  P
Sbjct: 487 SEGAPVIPPSSGLPLPTPDARVGASTCGPPDHLLPPLGTPLPP 529


>gi|239748777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 350

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 58/217 (26%), Positives = 74/217 (34%), Gaps = 34/217 (15%)

Query: 2   PNLLYEWTRKTHVPANPAPFHTPRKRHPLSHTPHATAHPPSSPPPLH--------ITPVL 53
           P +  +W  + H   NP    +       S  P    HPPSS   +H          P L
Sbjct: 23  PRVNEQWGSRAH--PNPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSRLRAAPAAAPRL 80

Query: 54  PPTFPGTQPPRA-------LRLAEGSG---EGKQEEGRRAQARPRPLRPPWEVRGG---A 100
            P      P R        LR A  +    E     GRR + RP P  PP + R      
Sbjct: 81  LPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGP-SPPLQPRSRHPHT 139

Query: 101 RGPCSAPVGSRASSGPGLPSAAAARPARKTLTCQPRSIESPATASSAGCGSGPRVPQ--- 157
           R P + P  +     PG    A +RP  ++     RS  +P  A        PR P+   
Sbjct: 140 RYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARS-RTPGEAGPPRGDPRPRAPRPGD 198

Query: 158 ------VRLLGPGGRPSSPARDGSRRKAGHGCTSQSQ 188
                      P   P SP R   +R AG G T Q Q
Sbjct: 199 HPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQ 235



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 22/74 (29%), Positives = 28/74 (37%), Gaps = 13/74 (17%)

Query: 24  PRKRHPLSHTPHATAHPPSSPPPLHITPVLPPTFPGTQPPRALRLAEGSGEGKQEEGRRA 83
           P +  P    P    HP  SP  L  TP L P  PG +             GK+  G+  
Sbjct: 184 PPRGDPRPRAPRPGDHPRRSPA-LRETPSLSPPSPGRR------------NGKRAAGKGT 230

Query: 84  QARPRPLRPPWEVR 97
             +P+P  PP   R
Sbjct: 231 TPQPQPPPPPCATR 244


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 57/245 (23%), Positives = 74/245 (30%), Gaps = 14/245 (5%)

Query: 12   THVPANPAPFHTPRKRHPLSHTPHATAHPP-SSPPPLHITPVLPPTFPGTQPPR-ALRLA 69
            TH P  P+P   P        +P     PP  +P P  +    P   P T  P+ A  L+
Sbjct: 853  THSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALS 912

Query: 70   EGSGEGKQEEGRRA----QARPRPLRPPWEVRGGARGPCSAPVGSRASSGPGLPSAAAAR 125
              S   K+     A     A P P   P         P   P        P  P+A    
Sbjct: 913  MTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPS 972

Query: 126  PARKTLTCQPRSIESPATASSAGCGSGPRVPQVRLLGPGGRPSSPARDGSRRKAGHGCTS 185
            P     T  P+   +P  A+      GP  P      P G P+ PA      K     T 
Sbjct: 973  PKGGPATPSPKGAPTPPAATPPSPKGGPATP-----SPKGAPTPPAVTPPSPKGSPAATP 1027

Query: 186  QSQGDA---VAMEAEARGSPGGRVLMQELTLLPVEASLILSVVAAVLQLHSYRRPAGDTP 242
              +G +    A     +GSP    L +     P           A   L     P   TP
Sbjct: 1028 FPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATP 1087

Query: 243  DPRRG 247
               +G
Sbjct: 1088 PSPKG 1092



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 40/161 (24%), Positives = 60/161 (37%), Gaps = 19/161 (11%)

Query: 15   PANPAPFHTPRKRHPLSHTPHATAHPPSSPPPLHITPVLPPTFPGTQPPRALRLAEGSGE 74
            P  P P   P        +P  T   P++ P     P  P +  G  PP A    +G   
Sbjct: 1324 PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPA 1383

Query: 75   GKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVGSRASSGPGLPSAAAARPARKTLT-- 132
                  +R  A P P       +G    P   P+  + +    +    AA P++  LT  
Sbjct: 1384 MTPPSPKRGPAIPSP-------KGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPP 1436

Query: 133  -CQPRSI-ESPATASSAGCGSGPRVPQVRLLGPGGRPSSPA 171
               P S+ ++PAT++  G   GP  P  +     G P+ PA
Sbjct: 1437 AVTPVSLKKAPATSAPKG---GPATPSSK-----GDPTLPA 1469



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 44/171 (25%), Positives = 57/171 (33%), Gaps = 19/171 (11%)

Query: 15   PANPAPFHTPRKRHPLSHTPHATAHPPSSPPPLHITPVLPPTFPGTQPPRALRLAEGSGE 74
            P  PA      K  P +  P     PP++ PP     +  P   G   P  +      G 
Sbjct: 1241 PTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG 1300

Query: 75   GKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVGSRAS--SGPGLPSAAAARPARKTLT 132
                  + A   P    P  +   G   P  AP     +  S  G P+  A  P+ K   
Sbjct: 1301 PATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGP 1360

Query: 133  CQPRSIESP----ATASSAGCGS--------GPRVPQVRLLGPGGRPSSPA 171
              P S E P    AT S  G  +        GP +P      P G P+SPA
Sbjct: 1361 TTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIP-----SPKGDPTSPA 1406



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 40/169 (23%), Positives = 52/169 (30%), Gaps = 9/169 (5%)

Query: 15   PANPAPFHTPRKRHPLSHTPH---ATAHPPSSPPPLHITPVLPPTFPGTQPPRALRLAEG 71
            PA P+P   P        +P    AT  P  +P P  +TP  P   P   P         
Sbjct: 977  PATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPP 1036

Query: 72   SGEGKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVGSRASSGPGLPSAAAARPARKTL 131
            +      +G  A A P P   P         P   P        P  P+A    P     
Sbjct: 1037 AATPPSPKGSPA-ATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPA 1095

Query: 132  TCQPRSIESPATASSAGCGSGPRVPQVRLLGPGGRPSSPARDGSRRKAG 180
            T  P+    P  A+      G   P  +     G P++PA      K G
Sbjct: 1096 TPSPKGAPMPPAATPPSPKGGLATPPHK-----GAPTTPAATPPSPKGG 1139



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 44/175 (25%), Positives = 60/175 (34%), Gaps = 28/175 (16%)

Query: 36   ATAHPPSSPPPLHITPVLPPTFPGTQPPRALRLAEGSGEGKQEEGRRAQARPRPLRPPWE 95
            AT+ P  +P P   TP  P   PGT PP+                    A   P   P  
Sbjct: 1302 ATSPPKGAPTPPAATPPSPKGSPGTPPPKG-------------------APTPPAVTPPS 1342

Query: 96   VRGGARGPCSAPVGSRASSGPGL---PSAAAARPARK--TLTCQPRSIESPATASSAGCG 150
             +G    P + P      + P     P+  AA P+ K       P     PA  S  G  
Sbjct: 1343 PKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKG-- 1400

Query: 151  SGPRVPQVRLLGPGGRPSSP-ARDGSRRKAGHGCTSQSQGDAVAMEAEARGSPGG 204
              P  P V  L P   P++P  R+G+   +    T  +       +A A  +P G
Sbjct: 1401 -DPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKG 1454



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 38/167 (22%), Positives = 52/167 (31%), Gaps = 14/167 (8%)

Query: 15   PANPAPFHTPRKRHPLSHTPHATAHPPSSPPPLHITPVLPPTFPGTQPPRALRLAEGSGE 74
            P  PA      K  P + +P     PP++ PP        P+  G   P A+      G 
Sbjct: 963  PTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGS 1022

Query: 75   GKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVGSRASSG-PGLPSAAAARPARKTLTC 133
                   +  + P    PP         P  +P  +    G P  P+A    P     T 
Sbjct: 1023 PAATPFPKGASTPPAATPP--------SPKGSPAATPLPKGAPTTPAATLPSPKGGPATP 1074

Query: 134  QPRSIESPATASSAGCGSGPRVPQVRLLGPGGRPSSPARDGSRRKAG 180
              +   +P  A+      GP  P      P G P  PA      K G
Sbjct: 1075 SLKGAPTPPAATPPSPKGGPATP-----SPKGAPMPPAATPPSPKGG 1116



 Score = 37.0 bits (84), Expect = 0.022
 Identities = 46/173 (26%), Positives = 57/173 (32%), Gaps = 30/173 (17%)

Query: 23   TPRKRHPLSHTPHATAHPPSSPPPLHITPVLPPTFPGTQPPRALRLAEGSGEGKQEEG-- 80
            TP    P      AT  P  +P     TP  P   P T PP+       +     + G  
Sbjct: 1220 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLA 1279

Query: 81   ---RRAQARPRPLRPPWEVRGGARGPCSAPVGSRASSGP-GLPSAAAARPARKTLTCQPR 136
                +    P  + PP            +P G  A+S P G P+  AA P        P 
Sbjct: 1280 TPPHKGAPNPAVVTPP------------SPKGGPATSPPKGAPTPPAATP--------PS 1319

Query: 137  SIESPATASSAGCGSGPRVPQVRLLGPGGRPSSPARDGSRRKAGHGCTSQSQG 189
               SP T    G    P  P V    P G P+ PA   S  K G    S  +G
Sbjct: 1320 PKGSPGTPPPKG---APTPPAVTPPSPKGTPTLPATTPS-SKGGPTTPSSKEG 1368



 Score = 36.2 bits (82), Expect = 0.037
 Identities = 37/169 (21%), Positives = 57/169 (33%), Gaps = 18/169 (10%)

Query: 26   KRHPLSHTPHATAHPPSSPPPLHITPVLPPTFPGTQPPRALRLAEGSGEGKQEEG----- 80
            K+ P   TP      PSS        V P T+ G   P+ L +         +E      
Sbjct: 1559 KKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPA 1618

Query: 81   ------RRAQARPRPLRPPWE---VRGGARGPCSAPVGSRASSGPGLPSAAAARPARKTL 131
                   +  A P P   P          +   ++P       G  +P A+   PA+K  
Sbjct: 1619 VTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGP 1678

Query: 132  TCQPRSIESPATAS----SAGCGSGPRVPQVRLLGPGGRPSSPARDGSR 176
            T     + +PA  S    +A    GP+  +     P   P   A++GS+
Sbjct: 1679 TALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSK 1727



 Score = 33.1 bits (74), Expect = 0.32
 Identities = 47/218 (21%), Positives = 70/218 (32%), Gaps = 32/218 (14%)

Query: 15   PANPAPFHTPRKRHPLSHTPHATAHPPSS--PPPLHITPVLPPTFPGTQPPRALRLAEGS 72
            PA PAP   P     +  +P      PSS   P      +L    P T  P+   +    
Sbjct: 1494 PATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAM 1553

Query: 73   GEGKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVGSRASSGPGL-PSAAAARPARKTL 131
                    ++  A P P   P           + P    ASS P + PS     P+ K L
Sbjct: 1554 ---TVPSPKKTPAIPTPKEAP-----------ATPSSKEASSPPAVTPSTYKGAPSPKEL 1599

Query: 132  -------TCQPRSIESPATASSAGCGSGPRVPQVRLLGPGGRPSSPARDGSRRK---AGH 181
                   +  P+   +P   +      GP  P      P G P+SP    S  K      
Sbjct: 1600 LIPPAVTSPSPKEAPTPPAVTPPSPEKGPATP-----APKGTPTSPPVTPSSLKDSPTSP 1654

Query: 182  GCTSQSQGDAVAMEAEARGSPGGRVLMQELTLLPVEAS 219
               +   G  V   ++   +  G   ++E+ + P   S
Sbjct: 1655 ASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPES 1692


>gi|239755634 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 449

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 44/143 (30%), Positives = 61/143 (42%), Gaps = 18/143 (12%)

Query: 82  RAQARPRPLRPPWEVRGGARGPC--SAPVGSRAS-SGPGLPSAAAA----------RPAR 128
           R +A  RP R    VRGG  G C  S   GS A+ SG G+P  + +          +  R
Sbjct: 49  RGRAERRPARGK-HVRGGGVGGCRDSRAGGSHAAPSGLGVPGDSESALGLLEPGPPKSLR 107

Query: 129 KTLTCQPRSIESPATASSAGCGSGP--RVPQV--RLLGPGGRPSSPARDGSRRKAGHGCT 184
            ++T        P+ ASSA  G  P  RVP       G   R  S   DG R ++G GC 
Sbjct: 108 ISVTLGQAPRAGPSAASSAAAGKTPPSRVPAEPSSRRGASKRRESWRTDGERLRSGRGCA 167

Query: 185 SQSQGDAVAMEAEARGSPGGRVL 207
             ++G   +++    G P   V+
Sbjct: 168 GAARGPDASLDTRREGWPRAAVV 190


>gi|239744429 PREDICTED: hypothetical protein XP_002343157 [Homo
           sapiens]
          Length = 449

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 44/143 (30%), Positives = 61/143 (42%), Gaps = 18/143 (12%)

Query: 82  RAQARPRPLRPPWEVRGGARGPC--SAPVGSRAS-SGPGLPSAAAA----------RPAR 128
           R +A  RP R    VRGG  G C  S   GS A+ SG G+P  + +          +  R
Sbjct: 49  RGRAERRPARGK-HVRGGGVGGCRDSRAGGSHAAPSGLGVPGDSESALGLLEPGPPKSLR 107

Query: 129 KTLTCQPRSIESPATASSAGCGSGP--RVPQV--RLLGPGGRPSSPARDGSRRKAGHGCT 184
            ++T        P+ ASSA  G  P  RVP       G   R  S   DG R ++G GC 
Sbjct: 108 ISVTLGQAPRAGPSAASSAAAGKTPPSRVPAEPSSRRGASKRRESWRTDGERLRSGRGCA 167

Query: 185 SQSQGDAVAMEAEARGSPGGRVL 207
             ++G   +++    G P   V+
Sbjct: 168 GAARGPDASLDTRREGWPRAAVV 190


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 44/152 (28%), Positives = 56/152 (36%), Gaps = 11/152 (7%)

Query: 58  PGTQPPRALRLAEGSGEGKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVGSRASSGPG 117
           PG   P+    A G+  GK + G   +  P  L     +RGGA  P   P G + ++GP 
Sbjct: 656 PGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPP--GPEGGKGAAGPP 713

Query: 118 LPSAAAARPARKTLTCQPRSIESPATASSAGCGSGPRVPQV----RLLGPGGRPSSPARD 173
            P  AA  P  + +  +   + SP      G   GP    V       GP G    P   
Sbjct: 714 GPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPA 773

Query: 174 GSRRKAGHGCTSQSQGDAVAMEAEARGSPGGR 205
           G     G G      G      A  RGSPG R
Sbjct: 774 GQPGDKGEGGAPGLPG-----IAGPRGSPGER 800



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 34/115 (29%), Positives = 40/115 (34%), Gaps = 11/115 (9%)

Query: 99  GARGPCS--------APVGSRASSGPGLPSAAAARPARKTLTCQPRSIESPATASSAGCG 150
           G RGP           P G R + GP  P  AA  P R  +   P     P +    G  
Sbjct: 489 GFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSD 548

Query: 151 SGPRVPQVRLLGPGGRPSSPARDGSRRKAG-HGCTSQSQGDAVAMEAEARGSPGG 204
             P  P  +  G  GRP  P   G R + G  G       D    +   RG PGG
Sbjct: 549 GKPGPPGSQ--GESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGG 601



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 76/320 (23%), Positives = 94/320 (29%), Gaps = 70/320 (21%)

Query: 15  PANPAPFHTPRKRHPLSHTPHATAHPPSSPPPLHITPVLPPTFPGTQPPRALRLAEGSGE 74
           P  P P  T    HP S        PP  P      P  PP  PG   P      +G   
Sbjct: 179 PGPPGPPGT--SGHPGSPGSPGYQGPPGEPG--QAGPSGPPGPPGAIGPSGPAGKDGESG 234

Query: 75  GKQEEGRRAQARPRPLRPP--------------WEVRGGARGPCSAP------------- 107
                G R    P  ++ P              ++ R G +G   AP             
Sbjct: 235 RPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENG 294

Query: 108 ----VGSRASSG----PGLPSAAAAR--PARKTLTCQPRSIESPATASSAGCGSGPRVPQ 157
               +G R + G    PGLP AA AR     +    QP     P TA   G         
Sbjct: 295 APGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGE-- 352

Query: 158 VRLLGPGGRPSSPARDGSRRKAGHGCTSQSQGDAVAMEAEARGSPGGRVLMQELTLLPVE 217
              +GP G P S    G R + G    + +QG          GSPGG+  M         
Sbjct: 353 ---VGPAGSPGSNGAPGQRGEPGPQGHAGAQGP--PGPPGINGSPGGKGEM--------- 398

Query: 218 ASLILSVVAAVLQLHSYRRPAGDTPDPRRGHHRHRRRQRGGGRGGGGRGGREAAATVHGN 277
               +     ++       PAG    P             G RGG G  G+  A    G 
Sbjct: 399 GPAGIPGAPGLMGARGPPGPAGANGAP-------------GLRGGAGEPGKNGAKGEPGP 445

Query: 278 AAASSSAAARGAAAATTIDG 297
                 A   G   A   DG
Sbjct: 446 RGERGEAGIPGVPGAKGEDG 465



 Score = 31.6 bits (70), Expect = 0.92
 Identities = 66/264 (25%), Positives = 83/264 (31%), Gaps = 29/264 (10%)

Query: 55   PTFPGTQPPRALRLAEGSGEGKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVGSRASS 114
            P  PG   PR      GS   + E G    A   P  P      G +G   AP G +   
Sbjct: 785  PGLPGIAGPR------GSPGERGETGPPGPAG-FPGAPGQNGEPGGKGERGAP-GEKGEG 836

Query: 115  GP----GLP--SAAAARPARKTLTCQPRSIESPATASSAGCGSGPRVPQVR-LLGPGGRP 167
            GP    G P  S  A  P  + +  +  S   P  A   G    P  P      GP G  
Sbjct: 837  GPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPS 896

Query: 168  SSPARDGSRRKAGH----GCTSQSQGDAVAMEAEARGSPGGRVLMQELTLLPVEASLILS 223
             SP +DG    AG+    G    S     A +   +GSPG +         P  A   L 
Sbjct: 897  GSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQG--------PPGAPGPLG 948

Query: 224  VVAAVLQLHSYRRPAGDTPDPRRGHHRHRRRQRGGGRGGGGRGGREAAATVHGNAAASSS 283
             +A +        P G  P PR        +   G  G  G  G        G    + +
Sbjct: 949  -IAGITGARGLAGPPG-MPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGT 1006

Query: 284  AAARGAAAATTIDGGGKEDAAGAG 307
            A   G       DG    D +  G
Sbjct: 1007 AGEPGRDGNPGSDGLPGRDGSPGG 1030



 Score = 31.6 bits (70), Expect = 0.92
 Identities = 32/91 (35%), Positives = 37/91 (40%), Gaps = 21/91 (23%)

Query: 41   PSSPPPL-----HITPVLPPTFPGTQPPRALRLAEGSGEGKQEEGRRAQARPRPLRPPWE 95
            PS PP       H  P+ PP   G +  R  R +EGS       G   Q  P P  PP  
Sbjct: 1144 PSGPPGKDGTSGHPGPIGPP---GPRGNRGERGSEGS------PGHPGQ--PGPPGPP-- 1190

Query: 96   VRGGARGPCSAPVGSRASSGPGLPSAAAARP 126
               GA GPC   VG+ A +G G   A    P
Sbjct: 1191 ---GAPGPCCGGVGAAAIAGIGGEKAGGFAP 1218



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 40/133 (30%), Positives = 46/133 (34%), Gaps = 11/133 (8%)

Query: 78  EEGRRAQARPRPLRPPWEVRG--GARGPCSAPVGSRASSGPGLPSAAAARPARKTLTCQP 135
           E GR     P   R    V G  G +G   AP  +    GPG P      P  K     P
Sbjct: 559 ESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQG--PPGKNGETGP 616

Query: 136 RSIESPATASSAGCGSGPRVPQ--VRLLGPGGRP---SSPARDGSRRKAGHGCTSQSQGD 190
           +    P         +GP  PQ    L G GG P     P   G +  AG       +GD
Sbjct: 617 QGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGD 676

Query: 191 AVAMEAEARGSPG 203
           A A     RG PG
Sbjct: 677 AGA--PGERGPPG 687


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 80/320 (25%), Positives = 110/320 (34%), Gaps = 39/320 (12%)

Query: 15  PANPAPFHTPRKRHPLSHTPHATAHPPSSPPPLHITPVL------PPTFPGT---QPPRA 65
           P +P+    P+   PL+  P   A PP   PP   TP L      P +FPG     P  +
Sbjct: 490 PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 549

Query: 66  LRLAEGSGEGKQEEGRRA----QARPRPLRPPWEVRGGARGPCSAPVGSRASSGPGLPSA 121
           L ++  +    Q     A    Q  P P   P  ++   R P   P    + SGP L  A
Sbjct: 550 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASP-TLQAPRRPPTPGP--DTSVSGPRLTLA 606

Query: 122 AAARPARKTLTCQPRSIESPATAS-SAGCGSGPRVPQVRLLGP-GGRPSSPARDGSRRKA 179
            A  P          ++  P  A  S+   S P   +    GP GG  +SP  D      
Sbjct: 607 LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAAC 666

Query: 180 GHGCTSQSQGDAVAMEAEARGSPGGRVLMQELTLLPVEASLILSVVAAVLQLHSYRRPAG 239
                S+     +A     RG+PG  +     T  P  A  + ++        +   P  
Sbjct: 667 HPAAWSRGPAPPLAF----RGAPGAPLPWPPAT-GPGSADGLCTIYETEGPESATPAPGA 721

Query: 240 DTPDPRRGHHRHRRRQRGGGRGGGGR------------GGREAAATVHGNAAASSSAAAR 287
             P P  G     +   G G G   R            G  +A+   H  +     AAA 
Sbjct: 722 LDPGPSPG-TSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAE 780

Query: 288 GAAAATTIDGGGKEDAAGAG 307
           GAA  +   GGG   A G G
Sbjct: 781 GAAGGS---GGGPGGAEGGG 797



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 75/312 (24%), Positives = 109/312 (34%), Gaps = 49/312 (15%)

Query: 14  VPANPAPFHTPRKRHPLSHTPHAT-AHPPSSPPPLHITPVL--PPTFPGTQPPRALRLAE 70
           +P+ PA F       P +  P +  A PP   PP+   P+L  PP+ P +   +A R   
Sbjct: 531 LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 590

Query: 71  GSGEGKQEEGRRAQARPRPLRPPWEVRGGAR---GPCSAPVGSRASS----------GPG 117
             G      G R      P  PP   R  +    GP  A   S A+S          GP 
Sbjct: 591 TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 650

Query: 118 LPSAAAARPARKTLTCQPRS-IESPATASSAGCGSGPRVPQVRLLGPG------------ 164
             +AA+  P  +   C P +    PA   +     G  +P     GPG            
Sbjct: 651 GGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETE 710

Query: 165 GRPSSPARDGSRRKAGHGCTSQSQGDAVAMEAEARGSPGGRVLMQELTLLPVEASLILSV 224
           G  S+    G+        TS  +  A A    +  SP  +  + EL L  ++AS++  +
Sbjct: 711 GPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPK-QARLGELPLGALQASVVQHL 769

Query: 225 VAAVLQLHSYRRPAGDTPDPRRGHHRHRRRQRGGGRGGGGRGGREAAATVHGNAAASSSA 284
           ++  L L +    AG                   G GGG  G      T    AA S + 
Sbjct: 770 LSRTLLLAAAEGAAG-------------------GSGGGPGGAEGGGVTGGARAALSDAE 810

Query: 285 AARGAAAATTID 296
             R A   + +D
Sbjct: 811 LGRWAELLSPLD 822



 Score = 35.0 bits (79), Expect = 0.084
 Identities = 37/119 (31%), Positives = 46/119 (38%), Gaps = 8/119 (6%)

Query: 29  PLSHTPHATAHPPSSPPPLHITPVLPPTFPGTQPPRALRLAEGSGEGKQEEGRRAQARPR 88
           PLS  P AT  PP +PP L + P+  P  P   PP +  LA  S +            P 
Sbjct: 385 PLS--PLATP-PPQAPPALALPPLQAPPSPPASPPLS-PLATPSPQAPNALAVHLLQAPF 440

Query: 89  PLRPPWEVRGGARGPCSAPVGSRASSGPGLPSAAAARPARKTLTCQPRSIESPATASSA 147
              P   V+     P S PV   A+     P + AA P    L   P    SP  + SA
Sbjct: 441 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP----LQVPPSPPASPPMSPSA 495



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 59/213 (27%), Positives = 75/213 (35%), Gaps = 42/213 (19%)

Query: 15  PANP--APFHTPRKRHP-------LSHTPHATAHPP----SSPPPLHITPVLPPTFPGTQ 61
           PA+P  +P  TP  + P       L   P   A PP    ++PPP    P+  P     +
Sbjct: 455 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAK 514

Query: 62  PPRALRLAEGSGEGKQEEGRRAQARPRPLRPPWEVRGGA--RGPCSAPVGSRASSGPGLP 119
           PP     A  +           QA P    PP    G A      S P+   A+  P  P
Sbjct: 515 PPPQAPPALATPP--------LQALP---SPPASFPGQAPFSPSASLPMSPLATPPPQAP 563

Query: 120 SAAAA--------RPARKTLTCQPRSIESPATASSAGCGSGPRVPQVRLLGPGGRPSSPA 171
              AA         PA  TL   PR   +P   +S    SGPR+      GP   P  P+
Sbjct: 564 PVLAAPLLQVPPSPPASPTLQA-PRRPPTPGPDTSV---SGPRLTLALAPGP---PPPPS 616

Query: 172 RDGSRRKAGHGCTSQSQGDAVAMEAEARGSPGG 204
           R  S   +G      S   A +   E RG   G
Sbjct: 617 RSPSSTLSGPDLAGHS-SSATSTPEELRGYDSG 648



 Score = 28.5 bits (62), Expect = 7.8
 Identities = 33/116 (28%), Positives = 45/116 (38%), Gaps = 9/116 (7%)

Query: 15  PANPAPFHTPRKRHPLSHTPHATAHP-PSSPPPLHITPVLPPTFPGTQPPRAL--RLAEG 71
           P  PA  H+      L+ TP   A P PS+PP L   P  PP  P +Q   +L     + 
Sbjct: 319 PTLPATPHSSSLTCQLA-TPLPLAPPSPSAPPSLQTLP-SPPATPPSQATTSLGSPTLQA 376

Query: 72  SGEGKQEEGRRAQARPRPLRPPW----EVRGGARGPCSAPVGSRASSGPGLPSAAA 123
           +            A P P  PP      ++     P S P+   A+  P  P+A A
Sbjct: 377 THSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA 432


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 80/320 (25%), Positives = 110/320 (34%), Gaps = 39/320 (12%)

Query: 15  PANPAPFHTPRKRHPLSHTPHATAHPPSSPPPLHITPVL------PPTFPGT---QPPRA 65
           P +P+    P+   PL+  P   A PP   PP   TP L      P +FPG     P  +
Sbjct: 451 PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 510

Query: 66  LRLAEGSGEGKQEEGRRA----QARPRPLRPPWEVRGGARGPCSAPVGSRASSGPGLPSA 121
           L ++  +    Q     A    Q  P P   P  ++   R P   P    + SGP L  A
Sbjct: 511 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASP-TLQAPRRPPTPGP--DTSVSGPRLTLA 567

Query: 122 AAARPARKTLTCQPRSIESPATAS-SAGCGSGPRVPQVRLLGP-GGRPSSPARDGSRRKA 179
            A  P          ++  P  A  S+   S P   +    GP GG  +SP  D      
Sbjct: 568 LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAAC 627

Query: 180 GHGCTSQSQGDAVAMEAEARGSPGGRVLMQELTLLPVEASLILSVVAAVLQLHSYRRPAG 239
                S+     +A     RG+PG  +     T  P  A  + ++        +   P  
Sbjct: 628 HPAAWSRGPAPPLAF----RGAPGAPLPWPPAT-GPGSADGLCTIYETEGPESATPAPGA 682

Query: 240 DTPDPRRGHHRHRRRQRGGGRGGGGR------------GGREAAATVHGNAAASSSAAAR 287
             P P  G     +   G G G   R            G  +A+   H  +     AAA 
Sbjct: 683 LDPGPSPG-TSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAE 741

Query: 288 GAAAATTIDGGGKEDAAGAG 307
           GAA  +   GGG   A G G
Sbjct: 742 GAAGGS---GGGPGGAEGGG 758



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 75/312 (24%), Positives = 109/312 (34%), Gaps = 49/312 (15%)

Query: 14  VPANPAPFHTPRKRHPLSHTPHAT-AHPPSSPPPLHITPVL--PPTFPGTQPPRALRLAE 70
           +P+ PA F       P +  P +  A PP   PP+   P+L  PP+ P +   +A R   
Sbjct: 492 LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 551

Query: 71  GSGEGKQEEGRRAQARPRPLRPPWEVRGGAR---GPCSAPVGSRASS----------GPG 117
             G      G R      P  PP   R  +    GP  A   S A+S          GP 
Sbjct: 552 TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 611

Query: 118 LPSAAAARPARKTLTCQPRS-IESPATASSAGCGSGPRVPQVRLLGPG------------ 164
             +AA+  P  +   C P +    PA   +     G  +P     GPG            
Sbjct: 612 GGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETE 671

Query: 165 GRPSSPARDGSRRKAGHGCTSQSQGDAVAMEAEARGSPGGRVLMQELTLLPVEASLILSV 224
           G  S+    G+        TS  +  A A    +  SP  +  + EL L  ++AS++  +
Sbjct: 672 GPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPK-QARLGELPLGALQASVVQHL 730

Query: 225 VAAVLQLHSYRRPAGDTPDPRRGHHRHRRRQRGGGRGGGGRGGREAAATVHGNAAASSSA 284
           ++  L L +    AG                   G GGG  G      T    AA S + 
Sbjct: 731 LSRTLLLAAAEGAAG-------------------GSGGGPGGAEGGGVTGGARAALSDAE 771

Query: 285 AARGAAAATTID 296
             R A   + +D
Sbjct: 772 LGRWAELLSPLD 783



 Score = 35.0 bits (79), Expect = 0.084
 Identities = 37/119 (31%), Positives = 46/119 (38%), Gaps = 8/119 (6%)

Query: 29  PLSHTPHATAHPPSSPPPLHITPVLPPTFPGTQPPRALRLAEGSGEGKQEEGRRAQARPR 88
           PLS  P AT  PP +PP L + P+  P  P   PP +  LA  S +            P 
Sbjct: 346 PLS--PLATP-PPQAPPALALPPLQAPPSPPASPPLS-PLATPSPQAPNALAVHLLQAPF 401

Query: 89  PLRPPWEVRGGARGPCSAPVGSRASSGPGLPSAAAARPARKTLTCQPRSIESPATASSA 147
              P   V+     P S PV   A+     P + AA P    L   P    SP  + SA
Sbjct: 402 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP----LQVPPSPPASPPMSPSA 456



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 59/213 (27%), Positives = 75/213 (35%), Gaps = 42/213 (19%)

Query: 15  PANP--APFHTPRKRHP-------LSHTPHATAHPP----SSPPPLHITPVLPPTFPGTQ 61
           PA+P  +P  TP  + P       L   P   A PP    ++PPP    P+  P     +
Sbjct: 416 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAK 475

Query: 62  PPRALRLAEGSGEGKQEEGRRAQARPRPLRPPWEVRGGA--RGPCSAPVGSRASSGPGLP 119
           PP     A  +           QA P    PP    G A      S P+   A+  P  P
Sbjct: 476 PPPQAPPALATPP--------LQALP---SPPASFPGQAPFSPSASLPMSPLATPPPQAP 524

Query: 120 SAAAA--------RPARKTLTCQPRSIESPATASSAGCGSGPRVPQVRLLGPGGRPSSPA 171
              AA         PA  TL   PR   +P   +S    SGPR+      GP   P  P+
Sbjct: 525 PVLAAPLLQVPPSPPASPTLQA-PRRPPTPGPDTSV---SGPRLTLALAPGP---PPPPS 577

Query: 172 RDGSRRKAGHGCTSQSQGDAVAMEAEARGSPGG 204
           R  S   +G      S   A +   E RG   G
Sbjct: 578 RSPSSTLSGPDLAGHS-SSATSTPEELRGYDSG 609



 Score = 32.3 bits (72), Expect = 0.54
 Identities = 31/106 (29%), Positives = 42/106 (39%), Gaps = 12/106 (11%)

Query: 29  PLSHTPHATAHP-----PSSPPPLHITPVLPPTFPGTQPPRAL--RLAEGSGEGKQEEGR 81
           PLS +P AT  P     PS+PP L   P  PP  P +Q   +L     + +         
Sbjct: 289 PLSSSPLATPSPSAPPSPSAPPSLQTLP-SPPATPPSQATTSLGSPTLQATHSFLPSPPL 347

Query: 82  RAQARPRPLRPPW----EVRGGARGPCSAPVGSRASSGPGLPSAAA 123
              A P P  PP      ++     P S P+   A+  P  P+A A
Sbjct: 348 SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA 393


>gi|40255272 xin actin-binding repeat containing 1 [Homo sapiens]
          Length = 1843

 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 59/215 (27%), Positives = 79/215 (36%), Gaps = 17/215 (7%)

Query: 13   HVPANPAPFHTP----RKRHPLSHTPHATAHPPSSPPPLHITPVLPPTFPGTQPPRALRL 68
            H  ++PA   TP     K   L  T      P   P P H+T   PP       P +   
Sbjct: 1293 HSHSSPAGQRTPGGSQTKTPKLDPTMPPKKKPQLPPKPAHLTQSHPPQRLPKPLPLSPSF 1352

Query: 69   AEGSGEGKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVG-SRASSGPGLPSAAAARPA 127
            +   G+ + + G R  A P+P + P  V  G       P G S+ S   GL S  A RP 
Sbjct: 1353 SSEVGQREHQRGERDTAIPQPAKVPTTVDQGHIPLARCPSGHSQPSLQHGL-STTAPRPT 1411

Query: 128  RKTLT-CQPRSIESPA------TASSAGCGSGPRVPQVRLLGPGGRPSSPARDGSRRKAG 180
            +   T    +S E P         +S   G GP   Q       G P SP      +K  
Sbjct: 1412 KNQATGSNAQSSEPPKLNALNHDPTSPQWGPGPSGEQPMEGSHQGAPESPDSLQRNQKEL 1471

Query: 181  HGCTSQSQGDAVAMEAEARGSPGGRVLMQELTLLP 215
             G  +Q Q    A+E EA  S   + L +    +P
Sbjct: 1472 QGLLNQVQ----ALEKEAASSVDVQALRRLFEAVP 1502


>gi|239754674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 480

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 84/350 (24%), Positives = 108/350 (30%), Gaps = 63/350 (18%)

Query: 3   NLLYEWTRKTHVPANPAPFHTPRKRHPLSH--TPHATAHPPSSPPPLHITPVLPPTFPGT 60
           +++  W+ + H   NP       K H   H   P       S P     TP LP   PG 
Sbjct: 56  DIIARWSAQ-HSMTNPKRSGDMGKYHAHGHLRAPVFPVAKGSVPSEGRATPPLP--HPGD 112

Query: 61  QPPRALRLAEGSGEGKQEEGRRAQAR-----------------PRPLRPPWEVRGGARGP 103
             PR  R   G   G  + G++ Q R                 PRP  PP    GG R  
Sbjct: 113 HHPRH-RKNRGPSAGTSQLGKKTQCRSLFLRTKGLCALLLELPPRP--PPNLQEGGQRAI 169

Query: 104 CSAP----------------VGSRASSGPGLPSAAAARPARKTLTCQPRSIESPATASSA 147
              P                 G R  S P LP   AA   +   T  P  +  P  A  A
Sbjct: 170 FQRPPVYLGNKPTPPRQEGSFGGRPKSQPPLPQETAAPAPQPGPTAPPARVREPGRAEGA 229

Query: 148 GCGSGPRVPQVRLLG----PGGRPSSPARDGSRRKAGHGCTSQSQGDAVAMEAEARG--- 200
                 R P++R       P   P + +R    R AG        G+  A      G   
Sbjct: 230 S-----REPRLRSRAARPPPAPGPGALSRASRSRAAGRPGPGFHGGEKAAAPRAPGGGGG 284

Query: 201 -SPGGRVLMQELTLLPVEASLILSVVAAVLQLHSYRRPAGDTPDPRRGHHRH----RRRQ 255
            +PG        +    +A  +       L+     R     P    G+       RRR+
Sbjct: 285 RNPGALGRAAPPSRARQDAWGLSGCATVGLRRGDCDRAGSSQPPATSGNGERCRFCRRRR 344

Query: 256 RGGGRGGGGRGGREAAATVHGNAAASSSAAARGAAAATTIDGGGKEDAAG 305
           R   RGGGG G  E     HG A+           AA    G G+    G
Sbjct: 345 R---RGGGGEG--EGTHATHGPASPPGRRHDEEVGAAVLRAGSGEGSRRG 389



 Score = 35.8 bits (81), Expect = 0.049
 Identities = 63/236 (26%), Positives = 79/236 (33%), Gaps = 35/236 (14%)

Query: 41  PSSPPPLHITPVLPPTFPGTQPPRALRLAEGSGEGKQEEG--RRAQARPRPLRPPWEVRG 98
           P S PPL      P   PG   P A     G  EG   E   R   ARP P   P  +  
Sbjct: 194 PKSQPPLPQETAAPAPQPGPTAPPARVREPGRAEGASREPRLRSRAARPPPAPGPGALSR 253

Query: 99  GARG-----PCSAPVGSRASSGPGLPSAAAARPARKTLTCQPRSIESPATASSAGCGS-G 152
            +R      P     G   ++ P  P     R         P S         +GC + G
Sbjct: 254 ASRSRAAGRPGPGFHGGEKAAAPRAPGGGGGRNPGALGRAAPPSRARQDAWGLSGCATVG 313

Query: 153 PRVPQVRLLGPGGRPSSPARDGS-----RRKAGHGCTSQSQGDAVAMEAEARGSPGGRVL 207
            R       G   +P + + +G      RR+   G   + +G           SP GR  
Sbjct: 314 LRRGDCDRAG-SSQPPATSGNGERCRFCRRRRRRGGGGEGEG---THATHGPASPPGRRH 369

Query: 208 MQELTLLPVEASLILSVVAAVLQLHS---YRRPAGDTPDPRRGHHRHRRRQRGGGR 260
            +E             V AAVL+  S    RR    TP PRR H   +R   GGGR
Sbjct: 370 DEE-------------VGAAVLRAGSGEGSRRGLQLTPPPRRVHGALQR--FGGGR 410


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 75/312 (24%), Positives = 109/312 (34%), Gaps = 49/312 (15%)

Query: 14   VPANPAPFHTPRKRHPLSHTPHAT-AHPPSSPPPLHITPVL--PPTFPGTQPPRALRLAE 70
            +P+ PA F       P +  P +  A PP   PP+   P+L  PP+ P +   +A R   
Sbjct: 800  LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 859

Query: 71   GSGEGKQEEGRRAQARPRPLRPPWEVRGGAR---GPCSAPVGSRASS----------GPG 117
              G      G R      P  PP   R  +    GP  A   S A+S          GP 
Sbjct: 860  TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 919

Query: 118  LPSAAAARPARKTLTCQPRS-IESPATASSAGCGSGPRVPQVRLLGPG------------ 164
              +AA+  P  +   C P +    PA   +     G  +P     GPG            
Sbjct: 920  GGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETE 979

Query: 165  GRPSSPARDGSRRKAGHGCTSQSQGDAVAMEAEARGSPGGRVLMQELTLLPVEASLILSV 224
            G  S+    G+        TS  +  A A    +  SP  +  + EL L  ++AS++  +
Sbjct: 980  GPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPK-QARLGELPLGALQASVVQHL 1038

Query: 225  VAAVLQLHSYRRPAGDTPDPRRGHHRHRRRQRGGGRGGGGRGGREAAATVHGNAAASSSA 284
            ++  L L +    AG                   G GGG  G      T    AA S + 
Sbjct: 1039 LSRTLLLAAAEGAAG-------------------GSGGGPGGAEGGGVTGGARAALSDAE 1079

Query: 285  AARGAAAATTID 296
              R A   + +D
Sbjct: 1080 LGRWAELLSPLD 1091



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 59/209 (28%), Positives = 76/209 (36%), Gaps = 28/209 (13%)

Query: 12  THVPANPAPFHTPRKRHPLSHTPHATAHPPSSPPPLHITPVL--PPTFPGTQPPRALRLA 69
           T  P  P P   P  + P S        P ++PPP  + P+L  PP      PP +L ++
Sbjct: 721 TPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPP-RVPPLLAAPPLQVPPSPPASLPMS 779

Query: 70  EGSGEGKQEEGRRA----QARPRPLRPPWEVRGGA--RGPCSAPVGSRASSGPGLPSAAA 123
             +    Q     A    QA P    PP    G A      S P+   A+  P  P   A
Sbjct: 780 PLAKPPPQAPPALATPPLQALP---SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 836

Query: 124 A--------RPARKTLTCQPRSIESPATASSAGCGSGPRVPQVRLLGPGGRPSSPARDGS 175
           A         PA  TL   PR   +P   +S    SGPR+      GP   P  P+R  S
Sbjct: 837 APLLQVPPSPPASPTLQA-PRRPPTPGPDTSV---SGPRLTLALAPGP---PPPPSRSPS 889

Query: 176 RRKAGHGCTSQSQGDAVAMEAEARGSPGG 204
              +G      S   A +   E RG   G
Sbjct: 890 STLSGPDLAGHS-SSATSTPEELRGYDSG 917



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 74/291 (25%), Positives = 95/291 (32%), Gaps = 63/291 (21%)

Query: 23  TPRKRHPLSHTPHATAHPPSSPPPLHITPVLPPTFPGTQPPRALRLAEGSGEGKQEEGRR 82
           +P    P+S  P AT  PP +PPPL   P+  P  P   PP +                 
Sbjct: 709 SPPASPPMS--PSATP-PPQAPPPLAAPPLQVPPSPPASPPMS----------------- 748

Query: 83  AQARPRPLRPPW----EVRGGARGPCSAPVGSRASSGPGLPSAAAARPARKTLTCQPRSI 138
             A P P  PP      ++     P S P+   A   P  P A A  P  + L   P S 
Sbjct: 749 PSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALAT-PPLQALPSPPASF 807

Query: 139 ESPATASSAG-------CGSGPRVPQV----RLLGPGGRPSSPARDGSRRKAGHGCTSQS 187
              A  S +            P+ P V     L  P   P+SP     RR    G  +  
Sbjct: 808 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV 867

Query: 188 QGDAVAMEAEARGSPGGRVLMQELTLLPVEASLILSVVAAVLQLHSYRRPAGDTPDPRRG 247
            G  + + A A G P            P   S   ++    L  HS    A  TP+  RG
Sbjct: 868 SGPRLTL-ALAPGPPP-----------PPSRSPSSTLSGPDLAGHS--SSATSTPEELRG 913

Query: 248 HHRHRRRQRGGGRGGGGRGGREAAATVHGNAAASSSAA-ARGAAAATTIDG 297
           +              G  GG  A+       AA   AA +RG A      G
Sbjct: 914 Y------------DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRG 952



 Score = 36.2 bits (82), Expect = 0.037
 Identities = 43/142 (30%), Positives = 53/142 (37%), Gaps = 10/142 (7%)

Query: 29  PLSHTPHATAHPPSSPPPLHITPVLPPTFPGTQPPRALRLAEGSGEGKQEEGRRAQARPR 88
           PLS  P AT  PP +PP L + P+  P  P   PP +  LA  S +            P 
Sbjct: 610 PLS--PLATP-PPQAPPXLALPPLQAPPSPPASPPLS-PLATPSPQAPNALAVHLLQAPF 665

Query: 89  PLRPPWEVRGGARGPCSAPVGSRASSGPGLPSAAAARPARKTLTCQPRSIESPATASSAG 148
              P   V+     P S PV   A+     P + AA P    L   P    SP  + SA 
Sbjct: 666 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP----LQVPPSPPASPPMSPSA- 720

Query: 149 CGSGPRVPQVRLLGPGGRPSSP 170
               P+ P      P   P SP
Sbjct: 721 -TPPPQAPPPLAAPPLQVPPSP 741



 Score = 32.7 bits (73), Expect = 0.41
 Identities = 43/163 (26%), Positives = 53/163 (32%), Gaps = 15/163 (9%)

Query: 19  APFHTPRKRHPLSHTPHATAHPPSSP------PPLHITPVLPPTFPGTQPPRALRLAEGS 72
           +P  +P   HPL       +H P +P      PPL     L P  P  Q P A       
Sbjct: 478 SPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAP--PSLQTPPASLTTPPL 535

Query: 73  GEGKQEEGRRAQARPRPLRPPWEVRGGARGPC--SAPVGSRASSGPGLPSAAAARP--AR 128
                      Q    PL  P         PC   AP     +  P  PS+ A  P  A 
Sbjct: 536 ENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAP 595

Query: 129 KTLTCQP-RSIESPATASSAGCGSGPRVPQVRLLGPGGRPSSP 170
             L   P + + SP  +  A     P+ P    L P   P SP
Sbjct: 596 PALASPPLQGLPSPPLSPLA--TPPPQAPPXLALPPLQAPPSP 636



 Score = 32.0 bits (71), Expect = 0.71
 Identities = 42/159 (26%), Positives = 59/159 (37%), Gaps = 19/159 (11%)

Query: 16  ANPAPFHTPRKRHPLSHTPHATAHP-PSSPPPLHITPVLPPTFPGTQPPRALRLAEGSGE 74
           A P P   P    P   TP   A P PS+PP L   P  P T P   PP           
Sbjct: 324 ATPLPATLPPS--PPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP-------SMTT 374

Query: 75  GKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPV---GSRASSGPGLPSAAAARPARKTL 131
              +     Q  P P++ P  +   +     +P+     +A++  G P+  A       L
Sbjct: 375 PPMQAPPSLQTIP-PIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQA---THSFL 430

Query: 132 TCQPRSIESPATASSAGCGSGPRVPQVRLLGPGGRPSSP 170
           T  PR  ++  T+ S    + P  P   L  P   P+SP
Sbjct: 431 TMSPRQTQASLTSPSRPASTPPDSPP--LQAPLSLPASP 467



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 30/115 (26%), Positives = 39/115 (33%), Gaps = 12/115 (10%)

Query: 9   TRKTHVPANPAPFHTPRKRHPLSHTPHATAHPPSSPPPLHITPVLPPTFPGTQPPRALRL 68
           T     P  PAP        PL+  P  T    ++PPP     +  P   G   P    L
Sbjct: 555 TPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPL 614

Query: 69  AEGSGEGKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVGSRASSGPGLPSAAA 123
           A              QA P    PP  ++     P S P+   A+  P  P+A A
Sbjct: 615 ATPP----------PQAPPXLALPP--LQAPPSPPASPPLSPLATPSPQAPNALA 657


>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 819

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 66/271 (24%), Positives = 97/271 (35%), Gaps = 37/271 (13%)

Query: 69  AEGSGEGKQEEGRRAQARPRPLRPPWEVRGGAR---GPCSAPVGSRASSGPGLPSAAAAR 125
           AE +GE     G +++ R +P R    V G      G  S       ++G         +
Sbjct: 506 AEAAGEKATAAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGGGGNK 565

Query: 126 PARKTLTCQPRSIESPATASSAGCGSGPRVPQVRLLGPGGRPSSPARDGSR----RKAGH 181
            +R     +PR     A A+    G G + P  +    G   S     G +    + AG 
Sbjct: 566 QSRGGGGNKPRQWGQTAAAAKTR-GGGDKQPGWQKAAAGVTKSRSGDGGKKAWRQKAAGT 624

Query: 182 GCTSQS------QGDAVAME------AEARGSPGGRVLMQELTLLPVEASLILSVVAAVL 229
           G  S+       Q DA A E      A +RGS G +   Q+    P  A    S  AAV 
Sbjct: 625 GAKSRKKPWRRGQKDAAAAEKAWATGATSRGSGGKQPRWQK----PAAAGSESSAAAAVG 680

Query: 230 QLHSYRRPAGDTPDPRRG-------------HHRHRRRQRGGGRGGGGRGGREAAATVHG 276
           Q    R+         RG               R ++ + G  RGGGG   R +      
Sbjct: 681 QEAEARKKPRRRRAKSRGDGGQNAAVGINPWQRRGKKPRLGKSRGGGGAKSRGSGGAKSR 740

Query: 277 NAAASSSAAARGAAAATTIDGGGKEDAAGAG 307
            +  + S + + AAA+ +  GGG +   G G
Sbjct: 741 GSGGAKSRSGKKAAASKSHGGGGAKRRRGGG 771



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 64/270 (23%), Positives = 97/270 (35%), Gaps = 60/270 (22%)

Query: 69  AEGSGEGKQEEGRRAQARPRPLRPPWEVRGGARGP--------CSAPVGSRASSGPGLPS 120
           A   G+  +  G++     +  R  W+   GA G          +A  G+++  G G   
Sbjct: 64  AAAGGKKARLRGQKGAVAGKEARQHWQKAAGAGGAENRGGGEQKAAAAGTKSLGGRGRKP 123

Query: 121 AAAARPARKTLTCQPR-SIESPATASSAGCGSGPR----VPQVRLLGPGGRPSSPARDGS 175
               + A  T + +PR   +  A A S   G+G +       V+  G G +P   A  G+
Sbjct: 124 RRRGQKAAATGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAAGVKSQG-GEKPQKAAAAGA 182

Query: 176 RRKAG-----HGCTSQSQGDAVAMEAEARG----SPGGRVLMQELTLLPVEASLILSVVA 226
           + ++G      G  S+   D    + EA+     + GGR                     
Sbjct: 183 KSRSGKKPRRRGAKSRGDEDKKGRQREAKSRFGKTRGGR--------------------- 221

Query: 227 AVLQLHSYRRPAGDTPDPRRGHHRHRRRQR---------GGGRGGGGRGGREAAATVHGN 277
              + H   +PA      RRG  +  ++QR         G  R G  RGG +      G 
Sbjct: 222 --RKKHRRPKPAAGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQ 279

Query: 278 AAASSSAAARGAAAATTIDGGGKEDAAGAG 307
            AA + A  RGAA A     G K  A G G
Sbjct: 280 NAALAGAKRRGAATA-----GEKPAAKGRG 304



 Score = 28.9 bits (63), Expect = 6.0
 Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 10/76 (13%)

Query: 239 GDTPDPRRGHHRHRRRQRGGGRGGGGRGGREAAATVHGNAAASSSAAARG---------A 289
           G +  PRR   +  + + G  R GGG+  R          AA + A +RG         +
Sbjct: 422 GGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKAR-QKAAEAGAESRGDKKQGRQKAS 480

Query: 290 AAATTIDGGGKEDAAG 305
           AA T   GGG +  +G
Sbjct: 481 AAGTKSRGGGLKSHSG 496


>gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens]
          Length = 1597

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 78/281 (27%), Positives = 103/281 (36%), Gaps = 64/281 (22%)

Query: 14   VPANPAPFH----TPRKRH--PLSHTPHATAH--PPSSPP-------PLHITPVL-PPTF 57
            +P+ P   H    TPR R+  PL  TP       PP S P       PL   P++ PPT 
Sbjct: 791  LPSTPDSSHHAQATPRWRYNKPLPPTPDLPQPHLPPISAPGSSRIYRPLPPLPIIDPPTE 850

Query: 58   PGTQPPRALRLAEGSGEGKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVGSRASSGPG 117
            P   PP++   +  +  G    G    A+ RP    W V      P  A  G  +     
Sbjct: 851  PPPLPPKSRGRSRSTRGGHMNSG--GHAKTRPACQDWTV------PLPASAGRTS----- 897

Query: 118  LPSAAAARPARKTLTCQPRSIESPATASSAG----CGSGPRVPQV-RLLGPGGR------ 166
             P A A      T T + +S  SP  A S      C S P  P    L GP  +      
Sbjct: 898  WPPATARSTESFTSTSRSKSEVSPGMAFSNMTNFLCPSSPTTPWTPELQGPTSKDEAGVS 957

Query: 167  --PSSPARDGSRRKAGHGCTSQSQGDAVAMEAEARG-SPGGRVLMQELTLLPVEASLILS 223
              P +PAR+  RR      T+  QG      A   G SP G+    E       + L L 
Sbjct: 958  EHPEAPAREPLRR------TTPQQG------ASGPGRSPVGQARQPE-----KPSHLHLE 1000

Query: 224  VVAAVLQLHSYRRPAGDTPD----PRRGHHRHRRRQRGGGR 260
              ++        RP GD+      P  G ++H+   R G R
Sbjct: 1001 KASSWPHRRDSGRPPGDSSGQAVAPSEGANKHKGWSRQGLR 1041



 Score = 29.3 bits (64), Expect = 4.6
 Identities = 31/125 (24%), Positives = 40/125 (32%), Gaps = 21/125 (16%)

Query: 15   PANPAPFHTPRKRHPLSHTPHATAHPPSSP---PPLHITPVLPPTFPGTQPPRALRLAEG 71
            P++P    TP  + P S      +  P +P   P    TP    + PG  P    R  E 
Sbjct: 934  PSSPTTPWTPELQGPTSKDEAGVSEHPEAPAREPLRRTTPQQGASGPGRSPVGQARQPEK 993

Query: 72   SGEGKQEEGRRAQARPRPLRPPWEVRG------------------GARGPCSAPVGSRAS 113
                  E+      R    RPP +  G                  G R P   P GS  S
Sbjct: 994  PSHLHLEKASSWPHRRDSGRPPGDSSGQAVAPSEGANKHKGWSRQGLRRPSILPEGSSDS 1053

Query: 114  SGPGL 118
             GP +
Sbjct: 1054 RGPAV 1058


>gi|33286436 gametogenetin [Homo sapiens]
          Length = 652

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 50/184 (27%), Positives = 61/184 (33%), Gaps = 21/184 (11%)

Query: 15  PANPAP---------FHTPRKRHPLSHTPHATAHPPSSPPPLHITPVLPPTFPGTQPPRA 65
           P  PAP         F  P    P+   P      P  PPP     + PP    T  P A
Sbjct: 403 PRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVA 462

Query: 66  LRLAEGSGEGKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVGSRASSGPGLPSAAAAR 125
             L  G G  +      A     P  PP      A  P  AP  + A   P + + A A 
Sbjct: 463 PPLTPGLGHKESALAPTA----APALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAA 518

Query: 126 PARKTLTCQPRSIESP--ATASSAGCGSGPR------VPQVRLLGPGGRPSSPARDGSRR 177
              KT T + +   +   AT      G GPR      VP     G GG  +S     + R
Sbjct: 519 APIKTRTRRNKGSRAARGATRKDGLHGDGPRERATATVPDSSGGGGGGSGASQTGAANTR 578

Query: 178 KAGH 181
            A H
Sbjct: 579 AARH 582



 Score = 32.7 bits (73), Expect = 0.41
 Identities = 54/229 (23%), Positives = 73/229 (31%), Gaps = 49/229 (21%)

Query: 18  PAPFHTPRKRHPLSHTPHATAHPPS------SPPPLHIT-----PVLPPTFPGT----QP 62
           PA    PR R  L  +      PPS       PPP  ++     P  P  FP      +P
Sbjct: 114 PAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKP 173

Query: 63  PRALRLAEGSGEGKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVGSRASSGPGLPSAA 122
           P  L       E +  + R   A   P  PP E + G R        +R  + P      
Sbjct: 174 PPPL-----PSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGE 228

Query: 123 AARPARK----TLTCQ-----------PRSIESPATASSAGCGSG-------PRVPQVRL 160
            A+PA      +L C+           P +  S A  +S G G G         +    +
Sbjct: 229 MAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEV 288

Query: 161 LGPGGRPSSPA-------RDGSRRKAGHGCTSQSQGDAVAMEAEARGSP 202
           L  G  P   A       R     + G G      G   A  ++AR  P
Sbjct: 289 LKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALP 337



 Score = 29.6 bits (65), Expect = 3.5
 Identities = 37/140 (26%), Positives = 46/140 (32%), Gaps = 12/140 (8%)

Query: 14  VPANPAPFHTPRKRHP-LSHTPHATAHPPSSPPPLHITPVLPPTFPGTQPPRALRLAEGS 72
           +P  P P   P  + P L  TP   A PP +P   H    L PT     PP    LA   
Sbjct: 437 LPPLPPPTPPPTLQPPALQPTPLPVA-PPLTPGLGHKESALAPTAAPALPP---ALAADQ 492

Query: 73  GEGKQEEGRRAQARPRPLRPPWEVRGGARGPCSAPVGSRASSGPGLPSAAAARPARKTLT 132
                       A P P          A  P +AP+ +R     G  +A  A        
Sbjct: 493 APAPSPAPAPTVAEPSP-------PVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHG 545

Query: 133 CQPRSIESPATASSAGCGSG 152
             PR   +     S+G G G
Sbjct: 546 DGPRERATATVPDSSGGGGG 565


>gi|169213235 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 308

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 70/240 (29%), Positives = 84/240 (35%), Gaps = 56/240 (23%)

Query: 46  PLHITPVLPPTFPGTQPPRALRLAEGSGEGKQEEGRRAQARPRPLRPPWEVRGGARGPCS 105
           PL+     PP  P   PP         G   + E  RA  RP     P  +  G R  CS
Sbjct: 60  PLYRVSAPPPAPPPPPPP---------GGPSRSERPRAGLRPGAFVSPGPL--GRRASCS 108

Query: 106 APVGSRAS---SGPGLPSAAAARPARKTLTCQPRSIESPATASSAGCGSGPRVPQVRLLG 162
              GS      S   L +A    PAR  +    R+        S G  S PR        
Sbjct: 109 GRAGSAGRLRCSAAALSAAQRGGPARAQVPPALRTF-------SPGPASPPRA------S 155

Query: 163 PGGRPSSPARDGS-----RRKAGH-------GCTSQSQGDAVAMEAEARGSPGGRVLMQE 210
           PGGRP S AR  S     RR   H       G  S+        +  ARG P   +    
Sbjct: 156 PGGRPGSEARGRSGAECARRVPLHHGPPGASGVGSERDRKFQLHQTPARGPPFPGI--SG 213

Query: 211 LTLLPVEASLILSVVAAVLQLHSYRRPAGDTPDPRRGHH------RHRRRQRGGGRGGGG 264
           +T  PV       V++ V + H  R P G +P    G        R  RR R  GR GGG
Sbjct: 214 MTRGPV-------VLSGVNRQH--RWPPGASPSRSLGEAGGERPARALRRPRAPGRAGGG 264



 Score = 33.1 bits (74), Expect = 0.32
 Identities = 48/180 (26%), Positives = 63/180 (35%), Gaps = 19/180 (10%)

Query: 44  PPPLHITPVLPPTFPG-TQPPRALRLAEGSGEGKQEEGRRAQ--ARPRPLR--PPWEVRG 98
           P    + P L    PG   PPRA   + G   G +  GR     AR  PL   PP     
Sbjct: 132 PARAQVPPALRTFSPGPASPPRA---SPGGRPGSEARGRSGAECARRVPLHHGPPGASGV 188

Query: 99  GARGPCSAPVGSRASSGPGLPSAAAARPARKTLTCQPRSIESPATAS---SAGCGSGPRV 155
           G+       +    + GP  P  +        L+   R    P  AS   S G   G R 
Sbjct: 189 GSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGGERP 248

Query: 156 PQVRLLGPGGRPSSPARDGSRRKAGHGCTSQSQGDAVAMEAEARGSPGGRVLMQELTLLP 215
            +        RP +P R G     G G  + S G  +A  A   G P    +++   LLP
Sbjct: 249 ARALR-----RPRAPGRAGGGGPPGGGIPACSIGPGLARLAALGGLPS---ILESSRLLP 300


>gi|169212744 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 308

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 70/240 (29%), Positives = 84/240 (35%), Gaps = 56/240 (23%)

Query: 46  PLHITPVLPPTFPGTQPPRALRLAEGSGEGKQEEGRRAQARPRPLRPPWEVRGGARGPCS 105
           PL+     PP  P   PP         G   + E  RA  RP     P  +  G R  CS
Sbjct: 60  PLYRVSAPPPAPPPPPPP---------GGPSRSERPRAGLRPGAFVSPGPL--GRRASCS 108

Query: 106 APVGSRAS---SGPGLPSAAAARPARKTLTCQPRSIESPATASSAGCGSGPRVPQVRLLG 162
              GS      S   L +A    PAR  +    R+        S G  S PR        
Sbjct: 109 GRAGSAGRLRCSAAALSAAQRGGPARAQVPPALRTF-------SPGPASPPRA------S 155

Query: 163 PGGRPSSPARDGS-----RRKAGH-------GCTSQSQGDAVAMEAEARGSPGGRVLMQE 210
           PGGRP S AR  S     RR   H       G  S+        +  ARG P   +    
Sbjct: 156 PGGRPGSEARGRSGAECARRVPLHHGPPGASGVGSERDRKFQLHQTPARGPPFPGI--SG 213

Query: 211 LTLLPVEASLILSVVAAVLQLHSYRRPAGDTPDPRRGHH------RHRRRQRGGGRGGGG 264
           +T  PV       V++ V + H  R P G +P    G        R  RR R  GR GGG
Sbjct: 214 MTRGPV-------VLSGVNRQH--RWPPGASPSRSLGEAGGERPARALRRPRAPGRAGGG 264



 Score = 33.1 bits (74), Expect = 0.32
 Identities = 48/180 (26%), Positives = 63/180 (35%), Gaps = 19/180 (10%)

Query: 44  PPPLHITPVLPPTFPG-TQPPRALRLAEGSGEGKQEEGRRAQ--ARPRPLR--PPWEVRG 98
           P    + P L    PG   PPRA   + G   G +  GR     AR  PL   PP     
Sbjct: 132 PARAQVPPALRTFSPGPASPPRA---SPGGRPGSEARGRSGAECARRVPLHHGPPGASGV 188

Query: 99  GARGPCSAPVGSRASSGPGLPSAAAARPARKTLTCQPRSIESPATAS---SAGCGSGPRV 155
           G+       +    + GP  P  +        L+   R    P  AS   S G   G R 
Sbjct: 189 GSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGGERP 248

Query: 156 PQVRLLGPGGRPSSPARDGSRRKAGHGCTSQSQGDAVAMEAEARGSPGGRVLMQELTLLP 215
            +        RP +P R G     G G  + S G  +A  A   G P    +++   LLP
Sbjct: 249 ARALR-----RPRAPGRAGGGGPPGGGIPACSIGPGLARLAALGGLPS---ILESSRLLP 300


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.131    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,115,601
Number of Sequences: 37866
Number of extensions: 1184086
Number of successful extensions: 14832
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 288
Number of HSP's successfully gapped in prelim test: 1287
Number of HSP's that attempted gapping in prelim test: 9516
Number of HSP's gapped (non-prelim): 5350
length of query: 307
length of database: 18,247,518
effective HSP length: 102
effective length of query: 205
effective length of database: 14,385,186
effective search space: 2948963130
effective search space used: 2948963130
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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