Guide to the Human Genome
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Search of human proteins with 119120834

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|119120834 tetraspanin 10 [Homo sapiens]
         (355 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|119120834 tetraspanin 10 [Homo sapiens]                            724   0.0  
gi|30425534 tetraspanin 33 [Homo sapiens]                             155   5e-38
gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens]       154   2e-37
gi|50511934 transmembrane 4 superfamily member 17 isoform b [Hom...   147   1e-35
gi|54859560 transmembrane 4 superfamily member 17 isoform a [Hom...   143   2e-34
gi|54859505 transmembrane 4 superfamily member 17 isoform c [Hom...   140   1e-33
gi|190194420 tetraspanin 14 isoform 1 [Homo sapiens]                  138   7e-33
gi|6912530 transmembrane 4 superfamily member 15 [Homo sapiens]       123   3e-28
gi|4502663 CD37 antigen isoform A [Homo sapiens]                       90   4e-18
gi|87159824 CD151 antigen [Homo sapiens]                               86   7e-17
gi|87159822 CD151 antigen [Homo sapiens]                               86   7e-17
gi|21237751 CD151 antigen [Homo sapiens]                               86   7e-17
gi|21237748 CD151 antigen [Homo sapiens]                               86   7e-17
gi|4504813 CD82 antigen isoform 1 [Homo sapiens]                       83   3e-16
gi|4502679 CD63 antigen isoform A [Homo sapiens]                       80   2e-15
gi|68800005 tetraspanin 4 isoform a [Homo sapiens]                     80   2e-15
gi|4507543 tetraspanin 4 isoform a [Homo sapiens]                      80   2e-15
gi|68800018 tetraspanin 4 isoform a [Homo sapiens]                     80   2e-15
gi|68800024 tetraspanin 4 isoform a [Homo sapiens]                     80   2e-15
gi|68800011 tetraspanin 4 isoform a [Homo sapiens]                     80   2e-15
gi|68799997 tetraspanin 4 isoform a [Homo sapiens]                     80   2e-15
gi|91199546 CD63 antigen isoform B [Homo sapiens]                      80   4e-15
gi|122937466 tetraspanin 11 [Homo sapiens]                             77   3e-14
gi|5729941 tetraspanin 9 [Homo sapiens]                                74   2e-13
gi|190341022 tetraspanin 14 isoform 2 [Homo sapiens]                   72   6e-13
gi|21264578 tetraspan 1 [Homo sapiens]                                 70   2e-12
gi|21265104 tetraspanin 7 [Homo sapiens]                               69   6e-12
gi|67782354 CD82 antigen isoform 2 [Homo sapiens]                      67   2e-11
gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens]         67   3e-11
gi|91807110 CD37 antigen isoform B [Homo sapiens]                      66   4e-11

>gi|119120834 tetraspanin 10 [Homo sapiens]
          Length = 355

 Score =  724 bits (1870), Expect = 0.0
 Identities = 355/355 (100%), Positives = 355/355 (100%)

Query: 1   MEEGERSPLLSQETAGQKPLSVHRPPTSGCLGPVPREDQAEAWGCSCCPPETKHQALSGT 60
           MEEGERSPLLSQETAGQKPLSVHRPPTSGCLGPVPREDQAEAWGCSCCPPETKHQALSGT
Sbjct: 1   MEEGERSPLLSQETAGQKPLSVHRPPTSGCLGPVPREDQAEAWGCSCCPPETKHQALSGT 60

Query: 61  PKKGPAPSLSPGSSCVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPADP 120
           PKKGPAPSLSPGSSCVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPADP
Sbjct: 61  PKKGPAPSLSPGSSCVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPADP 120

Query: 121 MLGLALGGLVVSAVSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQD 180
           MLGLALGGLVVSAVSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQD
Sbjct: 121 MLGLALGGLVVSAVSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQD 180

Query: 181 SLEHTLRVAIAHYQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLP 240
           SLEHTLRVAIAHYQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLP
Sbjct: 181 SLEHTLRVAIAHYQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLP 240

Query: 241 ASCCIDPREDGASVNDQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIA 300
           ASCCIDPREDGASVNDQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIA
Sbjct: 241 ASCCIDPREDGASVNDQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIA 300

Query: 301 VVLLQGAELLLAARLLGALAARRGAAYGPGARGEDRAGPQSPSPGAPPAAKPARG 355
           VVLLQGAELLLAARLLGALAARRGAAYGPGARGEDRAGPQSPSPGAPPAAKPARG
Sbjct: 301 VVLLQGAELLLAARLLGALAARRGAAYGPGARGEDRAGPQSPSPGAPPAAKPARG 355


>gi|30425534 tetraspanin 33 [Homo sapiens]
          Length = 283

 Score =  155 bits (392), Expect = 5e-38
 Identities = 87/249 (34%), Positives = 137/249 (55%), Gaps = 5/249 (2%)

Query: 73  SSCVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPADPMLGLALGGLVVS 132
           S  VKYL+F  N  F ++ ++ +A+G++   +K +  +     L  DP + L + G+++ 
Sbjct: 19  SPLVKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAAL--ACLAVDPAILLIVVGVLMF 76

Query: 133 AVSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVAIAH 192
            ++  G +G+L EN CLL+ FS  + A  +L+  AG L        +  +   +  AI H
Sbjct: 77  LLTFCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVH 136

Query: 193 YQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCS--SPGVQACSLPASCCIDPRED 250
           Y+DD DL+ L+D  Q    CCG  SY+DW QN+YFNCS  +P  + CS+P SCC+ P  D
Sbjct: 137 YRDDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCL-PTPD 195

Query: 251 GASVNDQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQGAELL 310
            A +N  CG G+   D   A +V+Y  GC   L  W+ +NL   GG A+ + + Q   +L
Sbjct: 196 QAVINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGIL 255

Query: 311 LAARLLGAL 319
           L+  L+  +
Sbjct: 256 LSQILVNQI 264


>gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens]
          Length = 268

 Score =  154 bits (388), Expect = 2e-37
 Identities = 107/278 (38%), Positives = 141/278 (50%), Gaps = 20/278 (7%)

Query: 57  LSGTPKKGPAPSLSPGSSCVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGS-----D 111
           +SG   KGP  S      C+KY IF  N  F  LG+  L IGLW    KG L +     D
Sbjct: 1   MSGKHYKGPEVSC-----CIKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSNISSITD 55

Query: 112 LGGPLPADPM-LGLALGGLVVSAVSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGAL 170
           LGG    DP+ L L +GG V+  +  AG +GAL ENT LL+ FS  +     LE  AG L
Sbjct: 56  LGG---FDPVWLFLVVGG-VMFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVL 111

Query: 171 VVALWGPLQDSLEHTLRVAIAHYQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNC- 229
                  ++D L   +   I  Y+DD DL+ L+D  Q   +CCGA    DW  N+YFNC 
Sbjct: 112 AFVFKDWIKDQLYFFINNNIRAYRDDIDLQNLIDFTQEYWQCCGAFGADDWNLNIYFNCT 171

Query: 230 -SSPGVQACSLPASCCI-DPREDGASVNDQCGFGVLRLDADAAQRVVYLEGCGPPLRRWL 287
            S+   + C +P SCC  DP ED   +N QCG+   +      Q V+Y +GC P   +WL
Sbjct: 172 DSNASRERCGVPFSCCTKDPAED--VINTQCGYDARQKPEVDQQIVIYTKGCVPQFEKWL 229

Query: 288 RANLAASGGYAIAVVLLQGAELLLAARLLGALAARRGA 325
           + NL    G  I + LLQ   + LA  L+  + A R +
Sbjct: 230 QDNLTIVAGIFIGIALLQIFGICLAQNLVSDIEAVRAS 267


>gi|50511934 transmembrane 4 superfamily member 17 isoform b [Homo
           sapiens]
          Length = 329

 Score =  147 bits (371), Expect = 1e-35
 Identities = 107/302 (35%), Positives = 149/302 (49%), Gaps = 28/302 (9%)

Query: 75  CVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGS-----DLGGPLPADPMLGLALGGL 129
           C KY +F  N  F +LG L LAIGLW    KG L +     DLGG    DP+    + G 
Sbjct: 16  CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG---LDPVWLFVVVGG 72

Query: 130 VVSAVSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVA 189
           V+S +  AG +GAL ENT LL+ FS  +     LE   G L       ++D L   +   
Sbjct: 73  VMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNN 132

Query: 190 IAHYQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCS--SPGVQACSLPASCCI-D 246
           +  Y+DD DL+ L+D  Q    CCGA    DW  N+YFNC+  +P  + C +P SCC+ D
Sbjct: 133 VKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRD 192

Query: 247 PREDGASVNDQCGFGV-LRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQ 305
           P ED   +N QCG+ V L+L+ +  Q  ++ +GC     +WL+ NL    G  + + LLQ
Sbjct: 193 PAED--VLNTQCGYDVRLKLELE-QQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQ 249

Query: 306 GAELLLAARLLGALAARRG--AAYGPGARGE----------DRAGPQSPS-PGAPPAAKP 352
              + LA  L+  + A +   + +                   AGPQ  S  GAP  A P
Sbjct: 250 IFGICLAQNLVSDIKAVKANWSKWNDDFENHWLTPTISEVLSTAGPQQNSLTGAPGPAPP 309

Query: 353 AR 354
           +R
Sbjct: 310 SR 311


>gi|54859560 transmembrane 4 superfamily member 17 isoform a [Homo
           sapiens]
          Length = 332

 Score =  143 bits (361), Expect = 2e-34
 Identities = 107/304 (35%), Positives = 147/304 (48%), Gaps = 29/304 (9%)

Query: 75  CVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGS-----DLGGPLPADPMLGLALGGL 129
           C KY +F  N  F +LG L LAIGLW    KG L +     DLGG    DP+    + G 
Sbjct: 16  CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG---LDPVWLFVVVGG 72

Query: 130 VVSAVSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVA 189
           V+S +  AG +GAL ENT LL+ FS  +     LE   G L       ++D L   +   
Sbjct: 73  VMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNN 132

Query: 190 IAHYQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCS--SPGVQACSLPASCCI-D 246
           +  Y+DD DL+ L+D  Q    CCGA    DW  N+YFNC+  +P  + C +P SCC+ D
Sbjct: 133 VKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRD 192

Query: 247 PREDGASVNDQCGFGV-LRLDAD--AAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVL 303
           P ED   +N QCG+ V L+L       Q  ++ +GC     +WL+ NL    G  + + L
Sbjct: 193 PAED--VLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIAL 250

Query: 304 LQGAELLLAARLLGALAARRG--AAYGPGARGE----------DRAGPQSPS-PGAPPAA 350
           LQ   + LA  L+  + A +   + +                   AGPQ  S  GAP  A
Sbjct: 251 LQIFGICLAQNLVSDIKAVKANWSKWNDDFENHWLTPTISEVLSTAGPQQNSLTGAPGPA 310

Query: 351 KPAR 354
            P+R
Sbjct: 311 PPSR 314


>gi|54859505 transmembrane 4 superfamily member 17 isoform c [Homo
           sapiens]
          Length = 266

 Score =  140 bits (354), Expect = 1e-33
 Identities = 95/252 (37%), Positives = 129/252 (51%), Gaps = 16/252 (6%)

Query: 75  CVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGS-----DLGGPLPADPMLGLALGGL 129
           C KY +F  N  F +LG L LAIGLW    KG L +     DLGG    DP+    + G 
Sbjct: 16  CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG---LDPVWLFVVVGG 72

Query: 130 VVSAVSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVA 189
           V+S +  AG +GAL ENT LL+ FS  +     LE   G L       ++D L   +   
Sbjct: 73  VMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNN 132

Query: 190 IAHYQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCS--SPGVQACSLPASCCI-D 246
           +  Y+DD DL+ L+D  Q    CCGA    DW  N+YFNC+  +P  + C +P SCC+ D
Sbjct: 133 VKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRD 192

Query: 247 PREDGASVNDQCGFGV-LRLDAD--AAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVL 303
           P ED   +N QCG+ V L+L       Q  ++ +GC     +WL+ NL    G  + + L
Sbjct: 193 PAED--VLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIAL 250

Query: 304 LQGAELLLAARL 315
           LQ   + LA  L
Sbjct: 251 LQIFGICLAQNL 262


>gi|190194420 tetraspanin 14 isoform 1 [Homo sapiens]
          Length = 270

 Score =  138 bits (348), Expect = 7e-33
 Identities = 90/251 (35%), Positives = 126/251 (50%), Gaps = 9/251 (3%)

Query: 77  KYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPA---DPMLGLALGGLVVSA 133
           KYL+F  N  F L G++ L +GLW  + KG L SDL         DP++ + + G+V+  
Sbjct: 16  KYLLFSYNIIFWLAGVVFLGVGLWAWSEKGVL-SDLTKVTRMHGIDPVVLVLMVGVVMFT 74

Query: 134 VSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVAIAHY 193
           +  AG +GAL EN CLL  F G I+    LE     L       ++D         I  Y
Sbjct: 75  LGFAGCVGALRENICLLNFFCGTIVLIFFLELAVAVLAFLFQDWVRDRFREFFESNIKSY 134

Query: 194 QDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCS--SPGVQACSLPASCCI-DPRED 250
           +DD DL+ L+D +Q   +CCGA   +DW  N+YFNCS  S   + C +P SCC+ DP + 
Sbjct: 135 RDDIDLQNLIDSLQKANQCCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCVPDPAQ- 193

Query: 251 GASVNDQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQGAELL 310
              VN QCG+ V           ++ +GC   L  WL  N+    G  IA+ LLQ   + 
Sbjct: 194 -KVVNTQCGYDVRIQLKSKWDESIFTKGCIQALESWLPRNIYIVAGVFIAISLLQIFGIF 252

Query: 311 LAARLLGALAA 321
           LA  L+  + A
Sbjct: 253 LARTLISDIEA 263


>gi|6912530 transmembrane 4 superfamily member 15 [Homo sapiens]
          Length = 294

 Score =  123 bits (308), Expect = 3e-28
 Identities = 73/236 (30%), Positives = 119/236 (50%), Gaps = 4/236 (1%)

Query: 76  VKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPADPMLGLALGGLVVSAVS 135
           +K+ + + +  F L+G L L++G++   V+      L     A P + L L G+V+  VS
Sbjct: 20  LKFSLIIYSTVFWLIGALVLSVGIYA-EVERQKYKTLESAFLA-PAIILILLGVVMFMVS 77

Query: 136 LAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVAIAHYQD 195
             G L +L +N  LL+ F   +   L++E + G + +       D L   +R  I +Y D
Sbjct: 78  FIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYYD 137

Query: 196 DPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCIDPREDGASVN 255
           D D + ++D VQ   +CCG   Y+DW +N Y +CS+PG  AC +P +CCI  R     VN
Sbjct: 138 DLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCI--RNTTEVVN 195

Query: 256 DQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQGAELLL 311
             CG+  +  +  + Q V+Y+ GC   +  W   N     G  + ++L Q   +LL
Sbjct: 196 TMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLL 251


>gi|4502663 CD37 antigen isoform A [Homo sapiens]
          Length = 281

 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 77/251 (30%), Positives = 111/251 (44%), Gaps = 22/251 (8%)

Query: 74  SCVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLG---GPLPADPMLGLALGGLV 130
           S +KY +F+ N  F +LG L    G+W L  K S  S +G    PL     + LA+ G+ 
Sbjct: 9   SLIKYFLFVFNLFFFVLGSLIFCFGIWILIDKTSFVSFVGLAFVPLQIWSKV-LAISGIF 67

Query: 131 VSAVSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVAI 190
              ++L G +GAL E  CLL  + G +L     +   G L+      L+ SL   +   I
Sbjct: 68  TMGIALLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRAQLERSLRDVVEKTI 127

Query: 191 AHYQDDPD---LRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCIDP 247
             Y  +P+        D VQ  LRCCG    QDW Q L       G +A  +P SC    
Sbjct: 128 QKYGTNPEETAAEESWDYVQFQLRCCGWHYPQDWFQVLILR--GNGSEAHRVPCSCYNLS 185

Query: 248 REDGASVNDQCGFGVL---------RLDAD----AAQRVVYLEGCGPPLRRWLRANLAAS 294
             + +++ D+     L         R  AD     A+  +Y EGC   L++WL  NL + 
Sbjct: 186 ATNDSTILDKVILPQLSRLGHLARSRHSADICAVPAESHIYREGCAQGLQKWLHNNLISI 245

Query: 295 GGYAIAVVLLQ 305
            G  + V LL+
Sbjct: 246 VGICLGVGLLE 256


>gi|87159824 CD151 antigen [Homo sapiens]
          Length = 253

 Score = 85.5 bits (210), Expect = 7e-17
 Identities = 66/238 (27%), Positives = 102/238 (42%), Gaps = 19/238 (7%)

Query: 72  GSSCVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPADPMLGLALGGLVV 131
           G+ C+KYL+F  N  F L GL  +A+G+W LA+K    S L           L + G VV
Sbjct: 12  GTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVV 71

Query: 132 SAVSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVAIA 191
               + G      E   LLR +   +L   +LE +AG L  A +  L   L+  L+  + 
Sbjct: 72  MVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMT 131

Query: 192 ---HYQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCIDPR 248
              H      +   +DQ+Q    CCG+ + QDW+ + +      G +   +P SCC    
Sbjct: 132 KRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRV--VPDSCC---- 185

Query: 249 EDGASVNDQCGFGVLRLDADAAQRVVYLE-GCGPPLRRWLRANLAASGGYAIAVVLLQ 305
               +V   CG        D A  +  +E GC   L  +++ +L   G   I +  +Q
Sbjct: 186 ---KTVVALCG------QRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQ 234


>gi|87159822 CD151 antigen [Homo sapiens]
          Length = 253

 Score = 85.5 bits (210), Expect = 7e-17
 Identities = 66/238 (27%), Positives = 102/238 (42%), Gaps = 19/238 (7%)

Query: 72  GSSCVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPADPMLGLALGGLVV 131
           G+ C+KYL+F  N  F L GL  +A+G+W LA+K    S L           L + G VV
Sbjct: 12  GTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVV 71

Query: 132 SAVSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVAIA 191
               + G      E   LLR +   +L   +LE +AG L  A +  L   L+  L+  + 
Sbjct: 72  MVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMT 131

Query: 192 ---HYQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCIDPR 248
              H      +   +DQ+Q    CCG+ + QDW+ + +      G +   +P SCC    
Sbjct: 132 KRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRV--VPDSCC---- 185

Query: 249 EDGASVNDQCGFGVLRLDADAAQRVVYLE-GCGPPLRRWLRANLAASGGYAIAVVLLQ 305
               +V   CG        D A  +  +E GC   L  +++ +L   G   I +  +Q
Sbjct: 186 ---KTVVALCG------QRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQ 234


>gi|21237751 CD151 antigen [Homo sapiens]
          Length = 253

 Score = 85.5 bits (210), Expect = 7e-17
 Identities = 66/238 (27%), Positives = 102/238 (42%), Gaps = 19/238 (7%)

Query: 72  GSSCVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPADPMLGLALGGLVV 131
           G+ C+KYL+F  N  F L GL  +A+G+W LA+K    S L           L + G VV
Sbjct: 12  GTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVV 71

Query: 132 SAVSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVAIA 191
               + G      E   LLR +   +L   +LE +AG L  A +  L   L+  L+  + 
Sbjct: 72  MVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMT 131

Query: 192 ---HYQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCIDPR 248
              H      +   +DQ+Q    CCG+ + QDW+ + +      G +   +P SCC    
Sbjct: 132 KRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRV--VPDSCC---- 185

Query: 249 EDGASVNDQCGFGVLRLDADAAQRVVYLE-GCGPPLRRWLRANLAASGGYAIAVVLLQ 305
               +V   CG        D A  +  +E GC   L  +++ +L   G   I +  +Q
Sbjct: 186 ---KTVVALCG------QRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQ 234


>gi|21237748 CD151 antigen [Homo sapiens]
          Length = 253

 Score = 85.5 bits (210), Expect = 7e-17
 Identities = 66/238 (27%), Positives = 102/238 (42%), Gaps = 19/238 (7%)

Query: 72  GSSCVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPADPMLGLALGGLVV 131
           G+ C+KYL+F  N  F L GL  +A+G+W LA+K    S L           L + G VV
Sbjct: 12  GTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVV 71

Query: 132 SAVSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVAIA 191
               + G      E   LLR +   +L   +LE +AG L  A +  L   L+  L+  + 
Sbjct: 72  MVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMT 131

Query: 192 ---HYQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCIDPR 248
              H      +   +DQ+Q    CCG+ + QDW+ + +      G +   +P SCC    
Sbjct: 132 KRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRV--VPDSCC---- 185

Query: 249 EDGASVNDQCGFGVLRLDADAAQRVVYLE-GCGPPLRRWLRANLAASGGYAIAVVLLQ 305
               +V   CG        D A  +  +E GC   L  +++ +L   G   I +  +Q
Sbjct: 186 ---KTVVALCG------QRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQ 234


>gi|4504813 CD82 antigen isoform 1 [Homo sapiens]
          Length = 267

 Score = 83.2 bits (204), Expect = 3e-16
 Identities = 73/256 (28%), Positives = 115/256 (44%), Gaps = 23/256 (8%)

Query: 72  GSSCVK---YLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGP-----LPADPMLG 123
           GS+C+K   Y +FL N  F +LG + L  G+W LA K S  S L        + A   +G
Sbjct: 2   GSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFIG 61

Query: 124 LALGGLVVSAVSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLE 183
           +   G V   +   G +GA+ E  CLL  +   +L  L+ +  AGAL     G L+  + 
Sbjct: 62  V---GAVTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMG 118

Query: 184 HTLRVAIAHYQD--DPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPA 241
             +   I  Y    +  L+   D VQ  ++CCG  S+ +W  N     + P V   + P 
Sbjct: 119 GIVTELIRDYNSSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAEL-MNRPEV---TYPC 174

Query: 242 SCCIDPREDGASVNDQCGF-----GVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGG 296
           SC +   ED  S++ + GF        +         VY EGC   ++ WL+ NL    G
Sbjct: 175 SCEVKGEEDN-SLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILG 233

Query: 297 YAIAVVLLQGAELLLA 312
             + V +++   ++L+
Sbjct: 234 VGVGVAIIELLGMVLS 249


>gi|4502679 CD63 antigen isoform A [Homo sapiens]
          Length = 238

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 61/253 (24%), Positives = 113/253 (44%), Gaps = 32/253 (12%)

Query: 72  GSSCVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSL---GSDLGGPLPAD--PMLGLAL 126
           G  CVK+L+++      LL   A A+GL  + V   L    + + G  P    P++ +A+
Sbjct: 6   GMKCVKFLLYVL-----LLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAV 60

Query: 127 GGLVVSAVSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTL 186
           G + +  V+  G  GA  EN CL+  F+  +   +++E  A          +     +  
Sbjct: 61  G-VFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNF 119

Query: 187 RVAIAHYQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCID 246
           R  + +Y  +     +LD++Q   +CCGAA+Y DW++        P +    +P SCCI 
Sbjct: 120 RQQMENYPKNNHTASILDRMQADFKCCGAANYTDWEK-------IPSMSKNRVPDSCCI- 171

Query: 247 PREDGASVNDQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQG 306
                 +V   CG        +  ++ ++ EGC   +  WLR N+      A+ +  ++ 
Sbjct: 172 ------NVTVGCGI-------NFNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFVEV 218

Query: 307 AELLLAARLLGAL 319
             ++ A  L+ ++
Sbjct: 219 LGIVFACCLVKSI 231


>gi|68800005 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 67/233 (28%), Positives = 100/233 (42%), Gaps = 28/233 (12%)

Query: 76  VKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPADPMLGLAL-GGLVVSAV 134
           VKYL+F  N  F L G   L +G+W  A +GS  + L    P+     L +  G  V A+
Sbjct: 9   VKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFAT-LSSSFPSLSAANLLIITGAFVMAI 67

Query: 135 SLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVAIAHY- 193
              G LGA+ EN CLL  F   +L   +LEA    L  A    +    +  L+  +  Y 
Sbjct: 68  GFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYG 127

Query: 194 -QDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCIDPREDGA 252
            Q +  L      +Q   RCCG ++Y DW + +Y         A  +P SCC++      
Sbjct: 128 TQGNVGLTNAWSIIQTDFRCCGVSNYTDWFE-VY--------NATRVPDSCCLE------ 172

Query: 253 SVNDQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQ 305
             ++ CG          A    +   C   ++ WL+ NL A G + +   L+Q
Sbjct: 173 -FSESCGL--------HAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQ 216


>gi|4507543 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 67/233 (28%), Positives = 100/233 (42%), Gaps = 28/233 (12%)

Query: 76  VKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPADPMLGLAL-GGLVVSAV 134
           VKYL+F  N  F L G   L +G+W  A +GS  + L    P+     L +  G  V A+
Sbjct: 9   VKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFAT-LSSSFPSLSAANLLIITGAFVMAI 67

Query: 135 SLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVAIAHY- 193
              G LGA+ EN CLL  F   +L   +LEA    L  A    +    +  L+  +  Y 
Sbjct: 68  GFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYG 127

Query: 194 -QDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCIDPREDGA 252
            Q +  L      +Q   RCCG ++Y DW + +Y         A  +P SCC++      
Sbjct: 128 TQGNVGLTNAWSIIQTDFRCCGVSNYTDWFE-VY--------NATRVPDSCCLE------ 172

Query: 253 SVNDQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQ 305
             ++ CG          A    +   C   ++ WL+ NL A G + +   L+Q
Sbjct: 173 -FSESCGL--------HAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQ 216


>gi|68800018 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 67/233 (28%), Positives = 100/233 (42%), Gaps = 28/233 (12%)

Query: 76  VKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPADPMLGLAL-GGLVVSAV 134
           VKYL+F  N  F L G   L +G+W  A +GS  + L    P+     L +  G  V A+
Sbjct: 9   VKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFAT-LSSSFPSLSAANLLIITGAFVMAI 67

Query: 135 SLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVAIAHY- 193
              G LGA+ EN CLL  F   +L   +LEA    L  A    +    +  L+  +  Y 
Sbjct: 68  GFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYG 127

Query: 194 -QDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCIDPREDGA 252
            Q +  L      +Q   RCCG ++Y DW + +Y         A  +P SCC++      
Sbjct: 128 TQGNVGLTNAWSIIQTDFRCCGVSNYTDWFE-VY--------NATRVPDSCCLE------ 172

Query: 253 SVNDQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQ 305
             ++ CG          A    +   C   ++ WL+ NL A G + +   L+Q
Sbjct: 173 -FSESCGL--------HAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQ 216


>gi|68800024 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 67/233 (28%), Positives = 100/233 (42%), Gaps = 28/233 (12%)

Query: 76  VKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPADPMLGLAL-GGLVVSAV 134
           VKYL+F  N  F L G   L +G+W  A +GS  + L    P+     L +  G  V A+
Sbjct: 9   VKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFAT-LSSSFPSLSAANLLIITGAFVMAI 67

Query: 135 SLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVAIAHY- 193
              G LGA+ EN CLL  F   +L   +LEA    L  A    +    +  L+  +  Y 
Sbjct: 68  GFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYG 127

Query: 194 -QDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCIDPREDGA 252
            Q +  L      +Q   RCCG ++Y DW + +Y         A  +P SCC++      
Sbjct: 128 TQGNVGLTNAWSIIQTDFRCCGVSNYTDWFE-VY--------NATRVPDSCCLE------ 172

Query: 253 SVNDQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQ 305
             ++ CG          A    +   C   ++ WL+ NL A G + +   L+Q
Sbjct: 173 -FSESCGL--------HAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQ 216


>gi|68800011 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 67/233 (28%), Positives = 100/233 (42%), Gaps = 28/233 (12%)

Query: 76  VKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPADPMLGLAL-GGLVVSAV 134
           VKYL+F  N  F L G   L +G+W  A +GS  + L    P+     L +  G  V A+
Sbjct: 9   VKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFAT-LSSSFPSLSAANLLIITGAFVMAI 67

Query: 135 SLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVAIAHY- 193
              G LGA+ EN CLL  F   +L   +LEA    L  A    +    +  L+  +  Y 
Sbjct: 68  GFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYG 127

Query: 194 -QDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCIDPREDGA 252
            Q +  L      +Q   RCCG ++Y DW + +Y         A  +P SCC++      
Sbjct: 128 TQGNVGLTNAWSIIQTDFRCCGVSNYTDWFE-VY--------NATRVPDSCCLE------ 172

Query: 253 SVNDQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQ 305
             ++ CG          A    +   C   ++ WL+ NL A G + +   L+Q
Sbjct: 173 -FSESCGL--------HAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQ 216


>gi|68799997 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 67/233 (28%), Positives = 100/233 (42%), Gaps = 28/233 (12%)

Query: 76  VKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPADPMLGLAL-GGLVVSAV 134
           VKYL+F  N  F L G   L +G+W  A +GS  + L    P+     L +  G  V A+
Sbjct: 9   VKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFAT-LSSSFPSLSAANLLIITGAFVMAI 67

Query: 135 SLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVAIAHY- 193
              G LGA+ EN CLL  F   +L   +LEA    L  A    +    +  L+  +  Y 
Sbjct: 68  GFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYG 127

Query: 194 -QDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCIDPREDGA 252
            Q +  L      +Q   RCCG ++Y DW + +Y         A  +P SCC++      
Sbjct: 128 TQGNVGLTNAWSIIQTDFRCCGVSNYTDWFE-VY--------NATRVPDSCCLE------ 172

Query: 253 SVNDQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQ 305
             ++ CG          A    +   C   ++ WL+ NL A G + +   L+Q
Sbjct: 173 -FSESCGL--------HAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQ 216


>gi|91199546 CD63 antigen isoform B [Homo sapiens]
          Length = 236

 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 60/240 (25%), Positives = 106/240 (44%), Gaps = 32/240 (13%)

Query: 72  GSSCVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSL---GSDLGGPLPAD--PMLGLAL 126
           G  CVK+L+++      LL   A A+GL  + V   L    + + G  P    P++ +A+
Sbjct: 6   GMKCVKFLLYVL-----LLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAV 60

Query: 127 GGLVVSAVSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTL 186
           G + +  V+  G  GA  EN CL+  F+  +   +++E  A          +     +  
Sbjct: 61  G-VFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNF 119

Query: 187 RVAIAHYQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCID 246
           R  + +Y  +     +LD++Q   +CCGAA+Y DW++        P +    +P SCCI 
Sbjct: 120 RQQMENYPKNNHTASILDRMQADFKCCGAANYTDWEK-------IPSMSKNRVPDSCCI- 171

Query: 247 PREDGASVNDQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQG 306
                 +V   CG        +  ++ ++ EGC   +  WLR N+      A+ +  + G
Sbjct: 172 ------NVTVGCGI-------NFNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFVLG 218


>gi|122937466 tetraspanin 11 [Homo sapiens]
          Length = 253

 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 66/243 (27%), Positives = 99/243 (40%), Gaps = 17/243 (6%)

Query: 76  VKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPADPMLGLALGGLVVSAVS 135
           +KYL+F+ NF F + G   LA+G+W L  K    S L     A     L   G++V    
Sbjct: 16  LKYLLFVFNFFFWVGGAAVLAVGIWTLVEKSGYLSVLASSTFAASAYILIFAGVLVMVTG 75

Query: 136 LAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVAIAHYQD 195
             G+   L E    L  +   +L   ++E VAG L    +  L D L+  L   +A    
Sbjct: 76  FLGFGAILWERKGCLSTYFCLLLVIFLVELVAGVLAHVYYQRLSDELKQHLNRTLAENYG 135

Query: 196 DP---DLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCIDPREDGA 252
            P    +   +D++Q   +CCG+ S  DWQ + Y        +   +P SCC        
Sbjct: 136 QPGATQITASVDRLQQDFKCCGSNSSADWQHSTYILLRE--AEGRQVPDSCC-------K 186

Query: 253 SVNDQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQGAELLLA 312
           +V  +CG       A  +       GC   L ++L  +L   G   I V  LQ   ++L 
Sbjct: 187 TVVVRCG-----QRAHPSNIYKVEGGCLTKLEQFLADHLLLMGAVGIGVACLQICGMVLT 241

Query: 313 ARL 315
             L
Sbjct: 242 CCL 244


>gi|5729941 tetraspanin 9 [Homo sapiens]
          Length = 239

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 56/234 (23%), Positives = 99/234 (42%), Gaps = 28/234 (11%)

Query: 75  CVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPADPMLGLALG-GLVVSA 133
           C+KY++FL N  F L G   L +G+W    +G+  +      P+     L +  G +V  
Sbjct: 8   CLKYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNFAT-FSPSFPSLSAANLVIAIGTIVMV 66

Query: 134 VSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLR--VAIA 191
               G LGA+ EN CLL  F   +L  L+ E +   L       + ++ +  L+  + + 
Sbjct: 67  TGFLGCLGAIKENKCLLLSFFIVLLVILLAELILLILFFVYMDKVNENAKKDLKEGLLLY 126

Query: 192 HYQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCIDPREDG 251
           H +++  L+   + +Q  +RCCG   Y DW   L  N         ++P  CC++  +  
Sbjct: 127 HTENNVGLKNAWNIIQAEMRCCGVTDYTDWYPVLGEN---------TVPDRCCMENSQG- 176

Query: 252 ASVNDQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQ 305
                 CG          A   ++  GC   ++ W   N    G   + ++++Q
Sbjct: 177 ------CGRN--------ATTPLWRTGCYEKVKMWFDDNKHVLGTVGMCILIMQ 216


>gi|190341022 tetraspanin 14 isoform 2 [Homo sapiens]
          Length = 147

 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 42/114 (36%), Positives = 58/114 (50%), Gaps = 5/114 (4%)

Query: 211 RCCGAASYQDWQQNLYFNCS--SPGVQACSLPASCCI-DPREDGASVNDQCGFGVLRLDA 267
           +CCGA   +DW  N+YFNCS  S   + C +P SCC+ DP +    VN QCG+ V     
Sbjct: 29  QCCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCVPDPAQ--KVVNTQCGYDVRIQLK 86

Query: 268 DAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQGAELLLAARLLGALAA 321
                 ++ +GC   L  WL  N+    G  IA+ LLQ   + LA  L+  + A
Sbjct: 87  SKWDESIFTKGCIQALESWLPRNIYIVAGVFIAISLLQIFGIFLARTLISDIEA 140


>gi|21264578 tetraspan 1 [Homo sapiens]
          Length = 241

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 67/253 (26%), Positives = 110/253 (43%), Gaps = 32/253 (12%)

Query: 74  SCVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPADPMLGLALG------ 127
           S +K ++ L N    L G   LA+G+W +++ G+    + GPL +  M  + +G      
Sbjct: 5   SFIKTMMILFNLLIFLCGAALLAVGIW-VSIDGASFLKIFGPLSSSAMQFVNVGYFLIAA 63

Query: 128 GLVVSAVSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLR 187
           G+VV A+   G  GA  E+ C L  F   +L   + E VA A+V  ++  +    EH L 
Sbjct: 64  GVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAE-VAAAVVALVYTTMA---EHFLT 119

Query: 188 VAIA-----HYQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPAS 242
           + +       Y    D   + +    GL+CCG  +Y D++ + YF  +S      + P  
Sbjct: 120 LLVVPAIKKDYGSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENS------AFPPF 173

Query: 243 CCIDPREDGASVNDQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVV 302
           CC D   + A  N+ C                 +EGC   L   +R N    GG A  + 
Sbjct: 174 CCNDNVTNTA--NETC--------TKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIG 223

Query: 303 LLQGAELLLAARL 315
            L+ A ++++  L
Sbjct: 224 GLELAAMIVSMYL 236


>gi|21265104 tetraspanin 7 [Homo sapiens]
          Length = 249

 Score = 68.9 bits (167), Expect = 6e-12
 Identities = 59/253 (23%), Positives = 104/253 (41%), Gaps = 17/253 (6%)

Query: 71  PGSSCVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPADPMLGLALGGLV 130
           P  +C+K L+ + +F F + G++ LA+G+WG    G+  S +       P + +  G  +
Sbjct: 10  PVITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAPYVLIGTGTTI 69

Query: 131 VSAVSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVAI 190
           V    L G       +  +L+ ++  +    + E VAG         ++D+   T   A+
Sbjct: 70  V-VFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAM 128

Query: 191 AHYQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCIDPRED 250
             Y  + +    +D VQ  L CCG  +Y +W  + YF           +P SCC++  E 
Sbjct: 129 QTYNGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYF-------LEHGIPPSCCMN--ET 179

Query: 251 GASVNDQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQGAELL 310
             +  D     V       A   V  +GC   +  ++  N+    G A  +   Q   +L
Sbjct: 180 DCNPQDLHNLTV-------AATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGML 232

Query: 311 LAARLLGALAARR 323
           LA  L   + A +
Sbjct: 233 LACCLSRFITANQ 245


>gi|67782354 CD82 antigen isoform 2 [Homo sapiens]
          Length = 242

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 70/254 (27%), Positives = 108/254 (42%), Gaps = 44/254 (17%)

Query: 72  GSSCVK---YLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGP-----LPADPMLG 123
           GS+C+K   Y +FL N  F +LG + L  G+W LA K S  S L        + A   +G
Sbjct: 2   GSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFIG 61

Query: 124 LALGGLVVSAVSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLE 183
           +   G V   +   G +GA+ E  CLL           +L+   G +V  L      S E
Sbjct: 62  V---GAVTMLMGFLGCIGAVNEVRCLLG----------LLKQEMGGIVTELIRDYNSSRE 108

Query: 184 HTLRVAIAHYQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASC 243
            +L+ A              D VQ  ++CCG  S+ +W  N     + P V   + P SC
Sbjct: 109 DSLQDA-------------WDYVQAQVKCCGWVSFYNWTDNAEL-MNRPEV---TYPCSC 151

Query: 244 CIDPREDGASVNDQCGF-----GVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYA 298
            +   ED  S++ + GF        +         VY EGC   ++ WL+ NL    G  
Sbjct: 152 EVKGEEDN-SLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVG 210

Query: 299 IAVVLLQGAELLLA 312
           + V +++   ++L+
Sbjct: 211 VGVAIIELLGMVLS 224


>gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens]
          Length = 245

 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 51/197 (25%), Positives = 88/197 (44%), Gaps = 23/197 (11%)

Query: 71  PGSSCVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPADPMLGLALGGLV 130
           P  +C K ++ +  F F + G++ LA+G+WG     +  S L       P + +A G ++
Sbjct: 12  PVITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVPFVLIATGTVI 71

Query: 131 VSAVSLAGYLGALCENTC-----LLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHT 185
           +    L G  G  C  TC     +L+ ++  +    ++E VA  +       +++S ++ 
Sbjct: 72  I----LLGTFG--CFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNN 125

Query: 186 LRVAIAHYQDDPDLR-FLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCC 244
              A+  Y    D R   +D++Q  L CCG   Y+DW    Y+  S  G      P SCC
Sbjct: 126 YEKALKQYNSTGDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYY--SEKG-----FPKSCC 178

Query: 245 ----IDPREDGASVNDQ 257
                 P+ D   VN++
Sbjct: 179 KLEDCTPQRDADKVNNE 195


>gi|91807110 CD37 antigen isoform B [Homo sapiens]
          Length = 213

 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 56/188 (29%), Positives = 81/188 (43%), Gaps = 18/188 (9%)

Query: 134 VSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVAIAHY 193
           ++L G +GAL E  CLL  + G +L     +   G L+      L+ SL   +   I  Y
Sbjct: 3   IALLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRAQLERSLRDVVEKTIQKY 62

Query: 194 QDDPD---LRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCIDPRED 250
             +P+        D VQ  LRCCG    QDW Q L       G +A  +P SC      +
Sbjct: 63  GTNPEETAAEESWDYVQFQLRCCGWHYPQDWFQVLILR--GNGSEAHRVPCSCYNLSATN 120

Query: 251 GASVNDQCGFGVL---------RLDAD----AAQRVVYLEGCGPPLRRWLRANLAASGGY 297
            +++ D+     L         R  AD     A+  +Y EGC   L++WL  NL +  G 
Sbjct: 121 DSTILDKVILPQLSRLGHLARSRHSADICAVPAESHIYREGCAQGLQKWLHNNLISIVGI 180

Query: 298 AIAVVLLQ 305
            + V LL+
Sbjct: 181 CLGVGLLE 188


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.138    0.437 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,900,051
Number of Sequences: 37866
Number of extensions: 883147
Number of successful extensions: 5098
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 75
Number of HSP's successfully gapped in prelim test: 58
Number of HSP's that attempted gapping in prelim test: 4882
Number of HSP's gapped (non-prelim): 203
length of query: 355
length of database: 18,247,518
effective HSP length: 103
effective length of query: 252
effective length of database: 14,347,320
effective search space: 3615524640
effective search space used: 3615524640
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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