Guide to the Human Genome
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Search of human proteins with 239753547

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239753547 PREDICTED: similar to 1700112C13Rik protein [Homo
sapiens]
         (282 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239753547 PREDICTED: similar to 1700112C13Rik protein [Homo s...   592   e-170
gi|239742014 PREDICTED: hypothetical protein XP_002342372 [Homo ...   592   e-170
gi|58218970 protease, serine, 36 [Homo sapiens]                       142   3e-34
gi|34098976 marapsin 2 [Homo sapiens]                                 142   4e-34
gi|148806900 epidermis-specific serine protease-like protein [Ho...   140   2e-33
gi|13994276 marapsin [Homo sapiens]                                   139   3e-33
gi|21614533 testisin isoform 3 [Homo sapiens]                         135   5e-32
gi|205360905 testis-specific serine protease 1 [Homo sapiens]         134   9e-32
gi|117956391 protease, serine, 33 [Homo sapiens]                      134   1e-31
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]             132   3e-31
gi|116256363 transmembrane protease, serine 13 [Homo sapiens]         130   2e-30
gi|5803197 testisin isoform 1 [Homo sapiens]                          129   2e-30
gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens]          129   3e-30
gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo ...   129   3e-30
gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo ...   129   3e-30
gi|4506153 prostasin preproprotein [Homo sapiens]                     128   5e-30
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]      126   2e-29
gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]            126   2e-29
gi|4503627 coagulation factor XI precursor [Homo sapiens]             126   2e-29
gi|11545839 protease, serine, 22 [Homo sapiens]                       126   2e-29
gi|33186882 testis serine protease 2 [Homo sapiens]                   125   4e-29
gi|21614531 testisin isoform 2 [Homo sapiens]                         125   4e-29
gi|110578663 hypothetical protein LOC203074 [Homo sapiens]            124   9e-29
gi|68508970 tryptase beta 2 precursor [Homo sapiens]                  124   1e-28
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap...   123   2e-28
gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa...   122   3e-28
gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sap...   122   3e-28
gi|7019563 testes-specific protease 50 [Homo sapiens]                 122   4e-28
gi|222831592 transmembrane protease, serine 7 [Homo sapiens]          119   3e-27
gi|148231605 ovochymase 2 [Homo sapiens]                              118   7e-27

>gi|239753547 PREDICTED: similar to 1700112C13Rik protein [Homo
           sapiens]
          Length = 282

 Score =  592 bits (1527), Expect = e-170
 Identities = 282/282 (100%), Positives = 282/282 (100%)

Query: 1   MACGPGDLQSLTSPLSSARLDYQPSIEGPWLRACGQTNVSCRVVKGKLVEVGKWPWQVSI 60
           MACGPGDLQSLTSPLSSARLDYQPSIEGPWLRACGQTNVSCRVVKGKLVEVGKWPWQVSI
Sbjct: 1   MACGPGDLQSLTSPLSSARLDYQPSIEGPWLRACGQTNVSCRVVKGKLVEVGKWPWQVSI 60

Query: 61  LFLGTYICSGSLIHHQWVLTAAHCLQRFKDLSLYSVMVGVHQRPENSTQLPLTRMVIHKD 120
           LFLGTYICSGSLIHHQWVLTAAHCLQRFKDLSLYSVMVGVHQRPENSTQLPLTRMVIHKD
Sbjct: 61  LFLGTYICSGSLIHHQWVLTAAHCLQRFKDLSLYSVMVGVHQRPENSTQLPLTRMVIHKD 120

Query: 121 FSNLMSQDIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHPD 180
           FSNLMSQDIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHPD
Sbjct: 121 FSNLMSQDIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHPD 180

Query: 181 SVKSCCEFIRECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHF 240
           SVKSCCEFIRECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHF
Sbjct: 181 SVKSCCEFIRECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHF 240

Query: 241 NQWIRTEVANIRFISRAGPAFLSPVFLTGYILLGSLSSLWLL 282
           NQWIRTEVANIRFISRAGPAFLSPVFLTGYILLGSLSSLWLL
Sbjct: 241 NQWIRTEVANIRFISRAGPAFLSPVFLTGYILLGSLSSLWLL 282


>gi|239742014 PREDICTED: hypothetical protein XP_002342372 [Homo
           sapiens]
          Length = 282

 Score =  592 bits (1527), Expect = e-170
 Identities = 282/282 (100%), Positives = 282/282 (100%)

Query: 1   MACGPGDLQSLTSPLSSARLDYQPSIEGPWLRACGQTNVSCRVVKGKLVEVGKWPWQVSI 60
           MACGPGDLQSLTSPLSSARLDYQPSIEGPWLRACGQTNVSCRVVKGKLVEVGKWPWQVSI
Sbjct: 1   MACGPGDLQSLTSPLSSARLDYQPSIEGPWLRACGQTNVSCRVVKGKLVEVGKWPWQVSI 60

Query: 61  LFLGTYICSGSLIHHQWVLTAAHCLQRFKDLSLYSVMVGVHQRPENSTQLPLTRMVIHKD 120
           LFLGTYICSGSLIHHQWVLTAAHCLQRFKDLSLYSVMVGVHQRPENSTQLPLTRMVIHKD
Sbjct: 61  LFLGTYICSGSLIHHQWVLTAAHCLQRFKDLSLYSVMVGVHQRPENSTQLPLTRMVIHKD 120

Query: 121 FSNLMSQDIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHPD 180
           FSNLMSQDIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHPD
Sbjct: 121 FSNLMSQDIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHPD 180

Query: 181 SVKSCCEFIRECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHF 240
           SVKSCCEFIRECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHF
Sbjct: 181 SVKSCCEFIRECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHF 240

Query: 241 NQWIRTEVANIRFISRAGPAFLSPVFLTGYILLGSLSSLWLL 282
           NQWIRTEVANIRFISRAGPAFLSPVFLTGYILLGSLSSLWLL
Sbjct: 241 NQWIRTEVANIRFISRAGPAFLSPVFLTGYILLGSLSSLWLL 282


>gi|58218970 protease, serine, 36 [Homo sapiens]
          Length = 855

 Score =  142 bits (359), Expect = 3e-34
 Identities = 93/289 (32%), Positives = 134/289 (46%), Gaps = 44/289 (15%)

Query: 13  SPLSSARLD--YQPSIEGPWLRACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSG 70
           SP+  A  D    P+ E P    CG+   S R+V G   + G WPWQVS+   G +IC G
Sbjct: 15  SPIPGAFQDSALSPTQEEPEDLDCGRPEPSARIVGGSNAQPGTWPWQVSLHHGGGHICGG 74

Query: 71  SLIHHQWVLTAAHCLQ---RFKDLSLYSVMVGVHQRP---ENSTQLPLTRMVIHKDFSNL 124
           SLI   WVL+AAHC       +  + +SV++GVH +    + +    +  +V+  ++S +
Sbjct: 75  SLIAPSWVLSAAHCFMTNGTLEPAAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPANYSQV 134

Query: 125 -MSQDIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHP---- 179
            +  D+ALL+L    S  P V PVCLP    +   G+ CW  GWG   +   L  P    
Sbjct: 135 ELGADLALLRLASPASLGPAVWPVCLPRASHRFVHGTACWATGWGDVQEADPLPLPWVLQ 194

Query: 180 --------DSVKSCCEFIRECFQFTLTV-------------------DSGSSLVCQMDKT 212
                   ++   C       F  TL +                   DSG  LVC+    
Sbjct: 195 EVELRLLGEATCQCLYSQPGPFNLTLQILPGMLCAGYPEGRRDTCQGDSGGPLVCEEGGR 254

Query: 213 WIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWIRTEVANIRFISRAGPAF 261
           W Q G+ S+ F CG+R+ PG++T+ A +  WIR +V      S  GPAF
Sbjct: 255 WFQAGITSFGFGCGRRNRPGVFTAVATYEAWIREQVMG----SEPGPAF 299



 Score = 69.7 bits (169), Expect = 3e-12
 Identities = 41/130 (31%), Positives = 64/130 (49%), Gaps = 12/130 (9%)

Query: 46  GKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCL-------QRFKDLSLYSVMV 98
           GK    G WPW+  ++  G+  C G+L+   WVL  A C           +DL  + V++
Sbjct: 326 GKAPRPGAWPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRVLL 385

Query: 99  GVHQRPENSTQLPLTRMVIHKDFSNLMSQDIALLKLRDSISWSPFVQPVCLPNIKFKPSI 158
               R E      + R+V H++ S   + D+ALL+LR  ++ S   +PVCLP+ +     
Sbjct: 386 PSRPRAER-----VARLVQHENASWDNASDLALLQLRTPVNLSAASRPVCLPHPEHYFLP 440

Query: 159 GSMCWVIGWG 168
           GS C +  WG
Sbjct: 441 GSRCRLARWG 450



 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 58/240 (24%), Positives = 93/240 (38%), Gaps = 40/240 (16%)

Query: 54  WPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQR-----FKDLSLYSVMVGVHQRPENST 108
           WPW   +   G  +C+G L+   WVL A HC+ R        + +Y    G    P+   
Sbjct: 601 WPWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLPQGH- 659

Query: 109 QLPLTRMVIHKDFSNLMS--QDIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIG 166
              ++R+VI       +     +ALL+L   +  SP   P+CL      P  G+ CWV+G
Sbjct: 660 --QVSRLVISIRLPQHLGLRPPLALLELSSRVEPSPSALPICLHPAGIPP--GASCWVLG 715

Query: 167 WGTTGKKGFLNHPDSV----------------KSCCEFIRECFQFTLTVDSGSSLVCQM- 209
           W     +  +    S+                 + C    E  +    + S   L+CQM 
Sbjct: 716 WKEPQDRVPVAAAVSILTQRICDCLYQGILPPGTLCVLYAEGQENRCEMTSAPPLLCQMT 775

Query: 210 DKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWIRTEVANIRFISRAGPAFLSPVFLTG 269
           + +WI +G+       G R    ++ +      WI   V    F+  +G    SP + TG
Sbjct: 776 EGSWILVGMAVQ----GSRE---LFAAIGPEEAWISQTVGEANFLPPSG----SPHWPTG 824


>gi|34098976 marapsin 2 [Homo sapiens]
          Length = 326

 Score =  142 bits (357), Expect = 4e-34
 Identities = 91/300 (30%), Positives = 153/300 (51%), Gaps = 37/300 (12%)

Query: 14  PLSSARLDYQPSIEGPWLR---ACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSG 70
           P  +A +  QP  +G  L    ACG+ ++  +++ G      KWPWQVS+ + G ++C G
Sbjct: 28  PRVAALVHRQPENQGISLTGSVACGRPSMEGKILGGVPAPERKWPWQVSVHYAGLHVCGG 87

Query: 71  SLIHHQWVLTAAHCLQRFKDLSLYSVMVG-VHQR-PENSTQ-LPLTRMVIHKDFS--NLM 125
           S+++  WVL+AAHC  R K++ +Y + VG V+ R   N TQ   + R+++H  +   + +
Sbjct: 88  SILNEYWVLSAAHCFHRDKNIKIYDMYVGLVNLRVAGNHTQWYEVNRVILHPTYEMYHPI 147

Query: 126 SQDIALLKLRDSISWSPFVQPVCL--PNIKFKPSIGSMCWVIGWGTTGKKG-------FL 176
             D+AL++L+  I +S  V PVCL  P +       + CW  GWG   K+G        +
Sbjct: 148 GGDVALVQLKTRIVFSESVLPVCLATPEVNL---TSANCWATGWGLVSKQGETSDELQEM 204

Query: 177 NHPDSVKSCCEFIRECFQFTL-------------TV---DSGSSLVCQMDKTWIQIGVVS 220
             P  ++  C  +     + +             TV   DSG  LVC+ +++W+QIG+VS
Sbjct: 205 QLPLILEPWCHLLYGHMSYIMPDMLCAGDILNAKTVCEGDSGGPLVCEFNRSWLQIGIVS 264

Query: 221 WSFSCGQRHFPGIYTSTAHFNQWIRTEVANIRFISRAGPAFLSPVFLTGYILLGSLSSLW 280
           W   C    +PG+Y S ++F++WI   +      ++  PA LSP       +L ++ + W
Sbjct: 265 WGRGCSNPLYPGVYASVSYFSKWICDNIEITPTPAQPAPA-LSPALGPTLSVLMAMLAGW 323


>gi|148806900 epidermis-specific serine protease-like protein [Homo
           sapiens]
          Length = 328

 Score =  140 bits (352), Expect = 2e-33
 Identities = 85/278 (30%), Positives = 138/278 (49%), Gaps = 39/278 (14%)

Query: 31  LRACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQRFKD 90
           +  CGQ   S RVV G+    G+WPWQVS+ F   +IC GSL+  + +LTAAHC+Q    
Sbjct: 16  ISVCGQPVYSSRVVGGQDAAAGRWPWQVSLHFDHNFICGGSLVSERLILTAAHCIQPTWT 75

Query: 91  LSLYSVMVGVHQRPENSTQLP--LTRMVIHKDFSNLMSQDIALLKLRDSISWSPFVQPVC 148
              Y+V +G     ++  ++   ++++VIH  + +  + D+ALLKL   ++++  + P+C
Sbjct: 76  TFSYTVWLGSITVGDSRKRVKYYVSKIVIHPKYQD-TTADVALLKLSSQVTFTSAILPIC 134

Query: 149 LPNIKFKPSIGSMCWVIGWGTTGKKGFLNHPDSV---------KSCCE------------ 187
           LP++  + +I   CWV GWG   +    ++  ++         +  CE            
Sbjct: 135 LPSVTKQLAIPPFCWVTGWGKVKESSDRDYHSALQEAEVPIIDRQACEQLYNPIGIFLPA 194

Query: 188 ---FIRE---CFQFTLTV------DSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYT 235
               I+E   C   T  +      DSG  L C +D  WIQ GVVSW   CG +  PG+YT
Sbjct: 195 LEPVIKEDKICAGDTQNMKDSCKGDSGGPLSCHIDGVWIQTGVVSWGLECG-KSLPGVYT 253

Query: 236 STAHFNQWIRTEVANIRFISRAGPAFLSPVFLTGYILL 273
           +  ++ +WI   ++    +  +   FL P+ L    LL
Sbjct: 254 NVIYYQKWINATISRANNLDFSD--FLFPIVLLSLALL 289


>gi|13994276 marapsin [Homo sapiens]
          Length = 290

 Score =  139 bits (350), Expect = 3e-33
 Identities = 80/257 (31%), Positives = 120/257 (46%), Gaps = 36/257 (14%)

Query: 33  ACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQRFKDLS 92
           ACG+  +  R+V G+  + G+WPWQVSI   G++ C GSLI  QWVLTAAHC +   + S
Sbjct: 25  ACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETS 84

Query: 93  LYSVMVGVHQ--RPENSTQLPLTRMVIHKDF--SNLMSQDIALLKLRDSISWSPFVQPVC 148
           LY V++G  Q  +P         R V           S D+AL++L   + ++ ++ PVC
Sbjct: 85  LYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPVC 144

Query: 149 LPNIKFKPSIGSMCWVIGWGTTGKKGFLNHP-----------DSVK-------------- 183
           LP+       G  CWV GWG+  ++  L  P           D+ K              
Sbjct: 145 LPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQ 204

Query: 184 -------SCCEFIRECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTS 236
                    C    E  +     DSG  LVC + ++W+Q GV+SW   C +++ PG+Y  
Sbjct: 205 PKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYIR 264

Query: 237 TAHFNQWIRTEVANIRF 253
               + WI   +  ++F
Sbjct: 265 VTAHHNWIHRIIPKLQF 281


>gi|21614533 testisin isoform 3 [Homo sapiens]
          Length = 300

 Score =  135 bits (339), Expect = 5e-32
 Identities = 73/240 (30%), Positives = 120/240 (50%), Gaps = 24/240 (10%)

Query: 34  CGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQRFKDLS- 92
           CG+  ++ R+V G+  E+G+WPWQ S+    +++C  SL+ H+W LTAAHC + + DLS 
Sbjct: 33  CGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSD 92

Query: 93  ---------LYSVMVGVHQRPENSTQLPLTRMVIHKDFSNLMSQDIALLKLRDSISWSPF 143
                      + M          T+  ++ + +   +      DIAL+KL   ++++  
Sbjct: 93  PSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKH 152

Query: 144 VQPVCLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHPDSVK---------SCCEFIRECFQ 194
           +QP+CL    F+    + CWV GWG   +   L  P +++         S C  +   + 
Sbjct: 153 IQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYS 212

Query: 195 FTLTV-----DSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWIRTEVA 249
           F   +     DSG  L C  +  W QIGVVSW   CG+ + PG+YT+ +H  +WI+  +A
Sbjct: 213 FRKDIFGDMGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLMA 272


>gi|205360905 testis-specific serine protease 1 [Homo sapiens]
          Length = 318

 Score =  134 bits (337), Expect = 9e-32
 Identities = 84/277 (30%), Positives = 130/277 (46%), Gaps = 40/277 (14%)

Query: 5   PGDLQSLTSPLSSARLDYQPSIEGPWLRACGQTNVSCRVVKGKLVEVGKWPWQVSILFLG 64
           PG+L +L +   +AR   +P   G    ACG   +   V  G     G+WPWQ S+    
Sbjct: 21  PGELGALQAGPGAAR---RPG-GGGREEACGHREIHALVAGGVESARGRWPWQASLRLRR 76

Query: 65  TYICSGSLIHHQWVLTAAHCLQRFKDLSLYSVMVG-VHQRP------ENSTQLPLTRMVI 117
            + C GSL+  +WVL+AAHC Q+    S ++V +G +  RP        S++  +  +++
Sbjct: 77  RHRCGGSLLSRRWVLSAAHCFQKHYYPSEWTVQLGELTSRPTPWNLRAYSSRYKVQDIIV 136

Query: 118 HKDFSNLMSQDIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKG--- 174
           + D   ++  DIALL+L  S++++ ++QP+C+ +  F       CWV GWG     G   
Sbjct: 137 NPDALGVLRNDIALLRLASSVTYNAYIQPICIESSTFNFVHRPDCWVTGWGLISPSGTPL 196

Query: 175 --------------------FLNHPDSVKSC------CEFIRECFQFTLTVDSGSSLVCQ 208
                               +L    S +S       C    +    T   DSG  LVC 
Sbjct: 197 PPPYNLREAQVTILNNTRCNYLFEQPSSRSMIWDSMFCAGAEDGSVDTCKGDSGGPLVCD 256

Query: 209 MDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWIR 245
            D  W Q+G+VSW   CGQ + PG+YT+ + +  WIR
Sbjct: 257 KDGLWYQVGIVSWGMDCGQPNRPGVYTNISVYFHWIR 293


>gi|117956391 protease, serine, 33 [Homo sapiens]
          Length = 280

 Score =  134 bits (336), Expect = 1e-31
 Identities = 87/254 (34%), Positives = 125/254 (49%), Gaps = 38/254 (14%)

Query: 33  ACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQRFKDLS 92
           ACGQ  +S R+V G+    G+WPWQ SI   G ++C GSLI  QWVLTAAHC  R    +
Sbjct: 27  ACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRALPA 86

Query: 93  LYSVMVGVHQRPENSTQ---LPLTRMVIHKDFSNLMSQ-DIALLKLRDSISWSPFVQPVC 148
            Y V +G  +    S +   +P+ R+++  D+S   ++ D+ALL+LR  +  S  VQPVC
Sbjct: 87  EYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARVQPVC 146

Query: 149 LPNIKFKPSIGSMCWVIGWGTTGKKGF-----------------------LNH-----PD 180
           LP    +P  G+ C V GWG+  + G                        L H     P 
Sbjct: 147 LPVPGARPPPGTPCRVTGWGSL-RPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQ 205

Query: 181 SVK-----SCCEFIRECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYT 235
           + +     S C    +  +     DSG  L C    +W+ +GVVSW   C   + PG+YT
Sbjct: 206 AERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPGVYT 265

Query: 236 STAHFNQWIRTEVA 249
           S A ++ WI+  V+
Sbjct: 266 SVATYSPWIQARVS 279


>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
          Length = 638

 Score =  132 bits (332), Expect = 3e-31
 Identities = 75/237 (31%), Positives = 121/237 (51%), Gaps = 29/237 (12%)

Query: 37  TNVSCRVVKGKLVEVGKWPWQVSI---LFLGTYICSGSLIHHQWVLTAAHCLQRFKDLSL 93
           T  S R+V G     G+WPWQVS+   L    ++C GSLI HQWVLTAAHC        +
Sbjct: 385 TKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDV 444

Query: 94  YSVMVGVHQRPENSTQLPLTRM---VIHKDFS-NLMSQDIALLKLRDSISWSPFVQPVCL 149
           + +  G+    + +   P +++   +IH+++  +  + DIAL+KL+  ++++ F +P+CL
Sbjct: 445 WRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICL 504

Query: 150 PNIKFKPSIGSMCWVIGWGTTGKKGFL-------NHPDSVKSCCEFIRECFQFTLTV--- 199
           P+     +I + CWV GWG + +KG +       N P      C+   + ++ T  +   
Sbjct: 505 PSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCA 564

Query: 200 ------------DSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWI 244
                       DSG  LVC+ +  W  +G+ SW   C +R  PG+YT  A +  WI
Sbjct: 565 GYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621


>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
          Length = 567

 Score =  130 bits (326), Expect = 2e-30
 Identities = 82/251 (32%), Positives = 123/251 (49%), Gaps = 34/251 (13%)

Query: 34  CGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHC--LQRFKDL 91
           CG   ++ R+V G L    KWPWQVS+ F  T+IC G+LI  QWVLTAAHC  + R K L
Sbjct: 317 CGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVL 376

Query: 92  SLYSVMVG---VHQRPENSTQLPLTRMVIHKDFSNLMSQ-DIALLKLRDSISWSPFVQPV 147
             + V  G   +HQ PE ++   +  ++I+ ++++     DIAL++L   ++ S  + P 
Sbjct: 377 EGWKVYAGTSNLHQLPEAAS---IAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPA 433

Query: 148 CLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHP---------DSVKSCCEFIRECFQFTLT 198
           CLP      S+   CW+ G+G T +      P            K C +++      T  
Sbjct: 434 CLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPR 493

Query: 199 V---------------DSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQW 243
           +               DSG  LVC+ +  W   GV SW   CGQR+ PG+YT       W
Sbjct: 494 MMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPW 553

Query: 244 IRTEV-ANIRF 253
           I +++ + +RF
Sbjct: 554 IYSKMESEVRF 564


>gi|5803197 testisin isoform 1 [Homo sapiens]
          Length = 314

 Score =  129 bits (325), Expect = 2e-30
 Identities = 73/254 (28%), Positives = 120/254 (47%), Gaps = 38/254 (14%)

Query: 34  CGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQRFKDLS- 92
           CG+  ++ R+V G+  E+G+WPWQ S+    +++C  SL+ H+W LTAAHC + + DLS 
Sbjct: 33  CGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSD 92

Query: 93  ---------LYSVMVGVHQRPENSTQLPLTRMVIHKDFSNLMSQDIALLKLRDSISWSPF 143
                      + M          T+  ++ + +   +      DIAL+KL   ++++  
Sbjct: 93  PSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKH 152

Query: 144 VQPVCLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHPDSVK---------SCCEFIRECFQ 194
           +QP+CL    F+    + CWV GWG   +   L  P +++         S C  +   + 
Sbjct: 153 IQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYS 212

Query: 195 FTLTV-------------------DSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYT 235
           F   +                   DSG  L C  +  W QIGVVSW   CG+ + PG+YT
Sbjct: 213 FRKDIFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYT 272

Query: 236 STAHFNQWIRTEVA 249
           + +H  +WI+  +A
Sbjct: 273 NISHHFEWIQKLMA 286


>gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens]
          Length = 410

 Score =  129 bits (324), Expect = 3e-30
 Identities = 79/249 (31%), Positives = 120/249 (48%), Gaps = 45/249 (18%)

Query: 32  RACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQRFKDL 91
           +ACG   VS R++ G      KWPWQVS+     + C GSLI  +WVLTAAHC+  F+  
Sbjct: 154 QACGH-RVS-RMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCV--FRGC 209

Query: 92  SLYS---VMVGVHQRPENSTQLPLTRMVIHKDFSNLMSQDIALLKLRDSISWSPFVQPVC 148
                  ++ G+ +  +    L       + DF+ L S DIAL  L  S+++S  +QP C
Sbjct: 210 GWEGGRWLLAGIGRWDQAWKHLEDIIFPSNFDFATLTS-DIALALLAYSVNYSSHIQPAC 268

Query: 149 LPNIKFKPSIGSMCWVIGWGTTGKK--------------GFLNHPDSVKSCCEFIR---- 190
           LP   F+   G+ CWV GWG   +                 + H    + CCE ++    
Sbjct: 269 LPEKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRH----EKCCEMLKNKNI 324

Query: 191 ---------------ECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYT 235
                          +  +     DSG  LVC+++ TW+Q+G+VSW   CG++ +PG+YT
Sbjct: 325 SKSKMVTRGTVCGYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYT 384

Query: 236 STAHFNQWI 244
             + + +WI
Sbjct: 385 EVSFYKKWI 393


>gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo
           sapiens]
          Length = 410

 Score =  129 bits (324), Expect = 3e-30
 Identities = 79/249 (31%), Positives = 120/249 (48%), Gaps = 45/249 (18%)

Query: 32  RACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQRFKDL 91
           +ACG   VS R++ G      KWPWQVS+     + C GSLI  +WVLTAAHC+  F+  
Sbjct: 154 QACGH-RVS-RMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCV--FRGC 209

Query: 92  SLYS---VMVGVHQRPENSTQLPLTRMVIHKDFSNLMSQDIALLKLRDSISWSPFVQPVC 148
                  ++ G+ +  +    L       + DF+ L S DIAL  L  S+++S  +QP C
Sbjct: 210 GWEGGRWLLAGIGRWDQAWKHLEDIIFPSNFDFATLTS-DIALALLAYSVNYSSHIQPAC 268

Query: 149 LPNIKFKPSIGSMCWVIGWGTTGKK--------------GFLNHPDSVKSCCEFIR---- 190
           LP   F+   G+ CWV GWG   +                 + H    + CCE ++    
Sbjct: 269 LPEKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRH----EKCCEMLKNKNI 324

Query: 191 ---------------ECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYT 235
                          +  +     DSG  LVC+++ TW+Q+G+VSW   CG++ +PG+YT
Sbjct: 325 SKSKMVTRGTVCGYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYT 384

Query: 236 STAHFNQWI 244
             + + +WI
Sbjct: 385 EVSFYKKWI 393


>gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo
           sapiens]
          Length = 410

 Score =  129 bits (324), Expect = 3e-30
 Identities = 79/249 (31%), Positives = 120/249 (48%), Gaps = 45/249 (18%)

Query: 32  RACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQRFKDL 91
           +ACG   VS R++ G      KWPWQVS+     + C GSLI  +WVLTAAHC+  F+  
Sbjct: 154 QACGH-RVS-RMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCV--FRGC 209

Query: 92  SLYS---VMVGVHQRPENSTQLPLTRMVIHKDFSNLMSQDIALLKLRDSISWSPFVQPVC 148
                  ++ G+ +  +    L       + DF+ L S DIAL  L  S+++S  +QP C
Sbjct: 210 GWEGGRWLLAGIGRWDQAWKHLEDIIFPSNFDFATLTS-DIALALLAYSVNYSSHIQPAC 268

Query: 149 LPNIKFKPSIGSMCWVIGWGTTGKK--------------GFLNHPDSVKSCCEFIR---- 190
           LP   F+   G+ CWV GWG   +                 + H    + CCE ++    
Sbjct: 269 LPEKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRH----EKCCEMLKNKNI 324

Query: 191 ---------------ECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYT 235
                          +  +     DSG  LVC+++ TW+Q+G+VSW   CG++ +PG+YT
Sbjct: 325 SKSKMVTRGTVCGYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYT 384

Query: 236 STAHFNQWI 244
             + + +WI
Sbjct: 385 EVSFYKKWI 393


>gi|4506153 prostasin preproprotein [Homo sapiens]
          Length = 343

 Score =  128 bits (322), Expect = 5e-30
 Identities = 87/284 (30%), Positives = 127/284 (44%), Gaps = 37/284 (13%)

Query: 4   GPGDLQSLTSPLSSARLDYQPSIEGPWLRACGQTNVSCRVVKGKLVEVGKWPWQVSILFL 63
           GPG L ++   L    L      EG     CG      R+  G     G+WPWQVSI + 
Sbjct: 8   GPGQLGAVAILLYLGLLRSGTGAEGAEA-PCGVAP-QARITGGSSAVAGQWPWQVSITYE 65

Query: 64  GTYICSGSLIHHQWVLTAAHCLQRFKDLSLYSVMVGVHQ---RPENSTQLPLTRMVIHKD 120
           G ++C GSL+  QWVL+AAHC         Y V +G HQ     E++    L  ++ H  
Sbjct: 66  GVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPS 125

Query: 121 FSNLMSQ-DIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHP 179
           +    SQ DIALL+L   I++S +++P+CLP        G  C V GWG       L  P
Sbjct: 126 YLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTP 185

Query: 180 DSV---------KSCC-------------EFIRE---CFQF------TLTVDSGSSLVCQ 208
             +         +  C              F++E   C  +          DSG  L C 
Sbjct: 186 KPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCP 245

Query: 209 MDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWIRTEVANIR 252
           ++  W   G+VSW  +CG R+ PG+YT  + +  WI+++V  ++
Sbjct: 246 VEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQ 289


>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
          Length = 321

 Score =  126 bits (317), Expect = 2e-29
 Identities = 90/280 (32%), Positives = 122/280 (43%), Gaps = 49/280 (17%)

Query: 34  CGQTNVSC---RVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQRFKD 90
           CG+  VS    R+V G     G WPWQ S+     ++C GSL+  QWVLTAAHC     +
Sbjct: 26  CGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLN 85

Query: 91  LSLYSVMVG---VHQRPENSTQLPLTRMVIHKDFSNL--MSQDIALLKLRDSISWSPFVQ 145
            S Y V +G   +   P  ST   + ++++H   S     S DIAL++L   ++ S  + 
Sbjct: 86  SSDYQVHLGELEITLSPHFST---VRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRIL 142

Query: 146 PVCLPNIKFKPSIGSMCWVIGWGTT------------------------------GKKGF 175
           PVCLP        G  CWV GWG T                              G  G 
Sbjct: 143 PVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVKVSVVDTETCRRDYPGPGGS 202

Query: 176 LNHPDSVKSCCEFIRECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYT 235
           +  PD +  C     +  Q     DSG  LVCQ++  W+Q G+VSW   CG+ + PG+YT
Sbjct: 203 ILQPDML--CARGPGDACQ----DDSGGPLVCQVNGAWVQAGIVSWGEGCGRPNRPGVYT 256

Query: 236 STAHFNQWIRTEVANIRFISRAGP--AFLSPVFLTGYILL 273
               +  WIR  +          P    L+  FL G  LL
Sbjct: 257 RVPAYVNWIRRHITASGGSESGYPRLPLLAGFFLPGLFLL 296


>gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
          Length = 275

 Score =  126 bits (316), Expect = 2e-29
 Identities = 84/247 (34%), Positives = 111/247 (44%), Gaps = 35/247 (14%)

Query: 33  ACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTY---ICSGSLIHHQWVLTAAHCL-QRF 88
           A GQ      +V G+     KWPWQVS+   G Y    C GSLIH QWVLTAAHC+    
Sbjct: 21  APGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDV 80

Query: 89  KDLSLYSVMVGVHQRPENSTQLPLTRMVIHKDF-SNLMSQDIALLKLRDSISWSPFVQPV 147
           KDL+   V +           LP++R+++H  F +  +  DIALL+L + ++ S  V  V
Sbjct: 81  KDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTV 140

Query: 148 CLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHPDSVKS---------CCEFIRECFQFT-- 196
            LP        G  CWV GWG       L  P  +K           C+       +T  
Sbjct: 141 TLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGD 200

Query: 197 -------------------LTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTST 237
                                 DSG  LVC+++ TW+Q GVVSW   C Q + PGIYT  
Sbjct: 201 DVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRV 260

Query: 238 AHFNQWI 244
            ++  WI
Sbjct: 261 TYYLDWI 267


>gi|4503627 coagulation factor XI precursor [Homo sapiens]
          Length = 625

 Score =  126 bits (316), Expect = 2e-29
 Identities = 77/253 (30%), Positives = 122/253 (48%), Gaps = 34/253 (13%)

Query: 26  IEGPWLRACGQTN-----VSCRVVKGKLVEVGKWPWQVSILFLGT---YICSGSLIHHQW 77
           I G  LR C   N     +  R+V G     G+WPWQV++        ++C GS+I +QW
Sbjct: 366 ISGYTLRLCKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQW 425

Query: 78  VLTAAHC---LQRFKDLSLYSVMVGVHQRPENSTQLPLTRMVIHKDFSNLMS-QDIALLK 133
           +LTAAHC   ++  K L +YS ++   +  E+++   +  ++IH  +    S  DIALLK
Sbjct: 426 ILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLK 485

Query: 134 LRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTG---------------------- 171
           L  +++++   +P+CLP+   +  I + CWV GWG                         
Sbjct: 486 LETTVNYTDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEEC 545

Query: 172 KKGFLNHPDSVKSCCEFIRECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFP 231
           +K +  H  + K  C   RE  +     DSG  L C+ ++ W  +G+ SW   C QR  P
Sbjct: 546 QKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERP 605

Query: 232 GIYTSTAHFNQWI 244
           G+YT+   +  WI
Sbjct: 606 GVYTNVVEYVDWI 618


>gi|11545839 protease, serine, 22 [Homo sapiens]
          Length = 317

 Score =  126 bits (316), Expect = 2e-29
 Identities = 90/299 (30%), Positives = 134/299 (44%), Gaps = 36/299 (12%)

Query: 2   ACGPGDLQSLTSPLSSARLDYQPSIEGPWLRACGQTNVSCRVVKGKLVEVGKWPWQVSIL 61
           A G G L + TS L  A      +   P   ACG+     RVV G+     +WPW VSI 
Sbjct: 9   ALGGGCLGTFTSLLLLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQ 68

Query: 62  FLGTYICSGSLIHHQWVLTAAHCLQ-RFKDLSLYSVMVGVHQ---RPENSTQLPLTRMVI 117
             GT+ C+GSL+  +WV+TAAHC +       L+SV++G  Q       S ++ +  +  
Sbjct: 69  KNGTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQKVGVAWVEP 128

Query: 118 HKDFS--NLMSQDIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKGF 175
           H  +S       DIAL++L  SI +S  V P+CLP+        + CW+ GWG+      
Sbjct: 129 HPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGVP 188

Query: 176 LNHPDSVKS----------------------------CCEFIRECFQFTLTVDSGSSLVC 207
           L HP +++                              C    E  +     DSG  L+C
Sbjct: 189 LPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERDACLGDSGGPLMC 248

Query: 208 QMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWIRTEVANIRFISRA--GPAFLSP 264
           Q+D  W+  G++SW   C +R+ PG+Y S +    W+   V  ++   RA  G A  +P
Sbjct: 249 QVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLRGRAQGGGALRAP 307


>gi|33186882 testis serine protease 2 [Homo sapiens]
          Length = 293

 Score =  125 bits (314), Expect = 4e-29
 Identities = 74/227 (32%), Positives = 113/227 (49%), Gaps = 39/227 (17%)

Query: 34  CGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQ-RFKDLS 92
           CG+T +  R+V G   E G+WPWQVS+   G +IC G+L+   WVLTA HC+  RF    
Sbjct: 73  CGRTPL--RIVGGVDAEEGRWPWQVSVRTKGRHICGGTLVTATWVLTAGHCISSRFH--- 127

Query: 93  LYSVMVGVHQRPENSTQLPLT--RMVIHKDFSNLMS--QDIALLKLRDSISWSPFVQPVC 148
            YSV +G       +T + ++  R  +H  FS + +   D+ALL+L+  ++++  +QP+C
Sbjct: 128 -YSVKMGDRSVYNENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFTSNIQPIC 186

Query: 149 LPNIKFKPSIGSMCWVIGWGTTGKKG-----FLNHPDSVKSCCEFIRECFQFTLTV---- 199
           +P   F+    + CWV GWG T ++       L   D    C E   +  Q  L+     
Sbjct: 187 IPQENFQVEGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKALSSTKDV 246

Query: 200 -------------------DSGSSLVCQMDKTWIQIGVVSWSFSCGQ 227
                              DSG  L C+ + TW+Q+G+VSW   CG+
Sbjct: 247 IIKGMVCGYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR 293


>gi|21614531 testisin isoform 2 [Homo sapiens]
          Length = 312

 Score =  125 bits (314), Expect = 4e-29
 Identities = 74/252 (29%), Positives = 121/252 (48%), Gaps = 36/252 (14%)

Query: 34  CGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQR-FKDLS 92
           CG+  ++ R+V G+  E+G+WPWQ S+    +++C  SL+ H+W LTAAHC +    D S
Sbjct: 33  CGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETDLSDPS 92

Query: 93  LYSVMVG-VHQRPE------NSTQLPLTRMVIHKDFSNLMSQDIALLKLRDSISWSPFVQ 145
            + V  G +   P         T+  ++ + +   +      DIAL+KL   ++++  +Q
Sbjct: 93  GWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQ 152

Query: 146 PVCLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHPDSVK---------SCCEFIRECFQFT 196
           P+CL    F+    + CWV GWG   +   L  P +++         S C  +   + F 
Sbjct: 153 PICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFR 212

Query: 197 LTV-------------------DSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTST 237
             +                   DSG  L C  +  W QIGVVSW   CG+ + PG+YT+ 
Sbjct: 213 KDIFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNI 272

Query: 238 AHFNQWIRTEVA 249
           +H  +WI+  +A
Sbjct: 273 SHHFEWIQKLMA 284


>gi|110578663 hypothetical protein LOC203074 [Homo sapiens]
          Length = 352

 Score =  124 bits (311), Expect = 9e-29
 Identities = 81/239 (33%), Positives = 117/239 (48%), Gaps = 33/239 (13%)

Query: 35  GQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQRFKDL--S 92
           G+T  S R+  G   EVG++PWQVSI       C GS+++  W+LTAAHCL   ++L   
Sbjct: 61  GRTRYS-RITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYS-EELFPE 118

Query: 93  LYSVMVGVHQRPENSTQL-PLTRMVIHKDFSNL-MSQDIALLKLRDSISWSPFVQPVCLP 150
             SV++G +     S ++  +  +++HKDF    M  DIALL L   I       P+CLP
Sbjct: 119 ELSVVLGTNDLTSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLP 178

Query: 151 NIKFKPSIGSMCWVIGWGTTG-------KKGFLNHPDSVKS----------------CCE 187
             +  P+    CWV GWG T        K   +  P  +                  C  
Sbjct: 179 T-QPGPATWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFPKLTKNMLCAG 237

Query: 188 FIRECFQFTLTVDSGSSLVC--QMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWI 244
           +  E +      DSG  LVC  +  + W Q+G++SW  SCG+++ PGIYTS  ++N WI
Sbjct: 238 YKNESYD-ACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWI 295


>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
          Length = 275

 Score =  124 bits (310), Expect = 1e-28
 Identities = 83/247 (33%), Positives = 110/247 (44%), Gaps = 35/247 (14%)

Query: 33  ACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTY---ICSGSLIHHQWVLTAAHCL-QRF 88
           A GQ      +V G+     KWPWQVS+     Y    C GSLIH QWVLTAAHC+    
Sbjct: 21  APGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCVGPDV 80

Query: 89  KDLSLYSVMVGVHQRPENSTQLPLTRMVIHKDF-SNLMSQDIALLKLRDSISWSPFVQPV 147
           KDL+   V +           LP++R+++H  F +  +  DIALL+L + ++ S  V  V
Sbjct: 81  KDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTV 140

Query: 148 CLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHPDSVKS---------CCEFIRECFQFT-- 196
            LP        G  CWV GWG       L  P  +K           C+       +T  
Sbjct: 141 TLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGD 200

Query: 197 -------------------LTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTST 237
                                 DSG  LVC+++ TW+Q GVVSW   C Q + PGIYT  
Sbjct: 201 DVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRV 260

Query: 238 AHFNQWI 244
            ++  WI
Sbjct: 261 TYYLDWI 267


>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
           sapiens]
          Length = 454

 Score =  123 bits (308), Expect = 2e-28
 Identities = 71/243 (29%), Positives = 110/243 (45%), Gaps = 27/243 (11%)

Query: 33  ACG-QTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQRFKDL 91
           ACG +   S R+V G +  + +WPWQ S+ F G ++C GS+I   W++TAAHC+      
Sbjct: 206 ACGHRRGYSSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYDLYLP 265

Query: 92  SLYSVMVGVHQRPENSTQLPLTRMVIH--KDFSNLMSQDIALLKLRDSISWSPFVQPVCL 149
             +++ VG+    +N     L   +++  K     +  DIAL+KL   ++++  +QPVCL
Sbjct: 266 KSWTIQVGLVSLLDNPAPSHLVEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCL 325

Query: 150 PNIKFKPSIGSMCWVIGWGTTG------------------KKGFLNHPDSVKSCCEFIRE 191
           PN +     G +CW  GWG T                        NH D           
Sbjct: 326 PNSEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSML 385

Query: 192 CFQF------TLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWIR 245
           C  +      +   DSG  LVCQ  + W  +G  S+   C + + PG+YT    F  WI 
Sbjct: 386 CAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIH 445

Query: 246 TEV 248
            ++
Sbjct: 446 EQM 448


>gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo
           sapiens]
          Length = 432

 Score =  122 bits (307), Expect = 3e-28
 Identities = 75/236 (31%), Positives = 114/236 (48%), Gaps = 25/236 (10%)

Query: 33  ACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQRFKDLS 92
           ACG++  + RVV G+   V  WPWQVSI +   ++C GS++   WVLTAAHC ++  D+ 
Sbjct: 190 ACGKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVF 249

Query: 93  LYSVMVGVHQRPENSTQLPLTRMVIHKDFSNLMSQDIALLKLRDSISWSPFVQPVCLPNI 152
            + V  G  +     +      ++I  +       DIAL+KL+  +++S  V+P+CLP  
Sbjct: 250 NWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFF 309

Query: 153 KFKPSIGSMCWVIGWGTTGKKG------------------FLNHPDSV------KSCCEF 188
             + +  +  W+IGWG T + G                    N  D+       K  C  
Sbjct: 310 DEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADDAYQGEVTEKMMCAG 369

Query: 189 IRECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWI 244
           I E    T   DSG  L+ Q D+ W  +G+VSW + CG    PG+YT  + +  WI
Sbjct: 370 IPEGGVDTCQGDSGGPLMYQSDQ-WHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWI 424


>gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo
           sapiens]
          Length = 437

 Score =  122 bits (307), Expect = 3e-28
 Identities = 75/236 (31%), Positives = 114/236 (48%), Gaps = 25/236 (10%)

Query: 33  ACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQRFKDLS 92
           ACG++  + RVV G+   V  WPWQVSI +   ++C GS++   WVLTAAHC ++  D+ 
Sbjct: 195 ACGKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVF 254

Query: 93  LYSVMVGVHQRPENSTQLPLTRMVIHKDFSNLMSQDIALLKLRDSISWSPFVQPVCLPNI 152
            + V  G  +     +      ++I  +       DIAL+KL+  +++S  V+P+CLP  
Sbjct: 255 NWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFF 314

Query: 153 KFKPSIGSMCWVIGWGTTGKKG------------------FLNHPDSV------KSCCEF 188
             + +  +  W+IGWG T + G                    N  D+       K  C  
Sbjct: 315 DEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADDAYQGEVTEKMMCAG 374

Query: 189 IRECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWI 244
           I E    T   DSG  L+ Q D+ W  +G+VSW + CG    PG+YT  + +  WI
Sbjct: 375 IPEGGVDTCQGDSGGPLMYQSDQ-WHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWI 429


>gi|7019563 testes-specific protease 50 [Homo sapiens]
          Length = 385

 Score =  122 bits (306), Expect = 4e-28
 Identities = 86/281 (30%), Positives = 132/281 (46%), Gaps = 54/281 (19%)

Query: 12  TSPLSSARLDYQ-PSIEG---PWLRACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYI 67
           T  L S  ++ Q P  EG   P+ R+CG +      ++       +WPW VS+   GT+I
Sbjct: 79  TQTLPSTTMETQFPVSEGKVDPY-RSCGFSYEQDPTLRDPEAVARRWPWMVSVRANGTHI 137

Query: 68  CSGSLIHHQWVLTAAHCLQRFKDLSLYSVMVG---VHQRPENSTQLPLTRMVIHKDFSNL 124
           C+G++I  QWVLT AHCL  ++D+ +YSV VG   + Q  + ++ +P+ ++++H  +   
Sbjct: 138 CAGTIIASQWVLTVAHCL-IWRDV-IYSVRVGSPWIDQMTQTASDVPVLQVIMHSRYRAQ 195

Query: 125 -------MSQDIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKG--- 174
                   + DI LLKL+  + +S +V+P+CLP   +     S C V GWG +   G   
Sbjct: 196 RFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRCTVTGWGLSKADGMWP 255

Query: 175 -----------FLNHPD-------------------SVKSCCEFI-RECFQFTLTVDSGS 203
                       LN+ +                   S   C E   RE F + LT   G 
Sbjct: 256 QFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCAEDTHREKFCYELT---GE 312

Query: 204 SLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWI 244
            LVC M+ TW  +G+VSW   C +   P IY   + +  WI
Sbjct: 313 PLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWI 353


>gi|222831592 transmembrane protease, serine 7 [Homo sapiens]
          Length = 717

 Score =  119 bits (298), Expect = 3e-27
 Identities = 75/240 (31%), Positives = 114/240 (47%), Gaps = 32/240 (13%)

Query: 42  RVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCL--QRFKDLSLYSVMVG 99
           R++ G     G WPWQVS+ F+G+  C  S+I  +W+L+AAHC    R  D + ++  +G
Sbjct: 479 RIIGGTDTLEGGWPWQVSLHFVGSAYCGASVISREWLLSAAHCFHGNRLSDPTPWTAHLG 538

Query: 100 VHQRPENSTQLPLTRMVIHKDF-SNLMSQDIALLKLRDSISW----SPFVQPVCLPNIKF 154
           ++ +       P+ R+V+H+ + S     DIALL+L  SI+W       +QP+C+P    
Sbjct: 539 MYVQGNAKFVSPVRRIVVHEYYNSQTFDYDIALLQL--SIAWPETLKQLIQPICIPPTGQ 596

Query: 155 KPSIGSMCWVIGWG---TTGKKGFLNHPD------------------SVKSCCEFIRECF 193
           +   G  CWV GWG       KG L                      + +  C  I    
Sbjct: 597 RVRSGEKCWVTGWGRRHEADNKGSLVLQQAEVELIDQTLCVSTYGIITSRMLCAGIMSGK 656

Query: 194 QFTLTVDSGSSLVC--QMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWIRTEVANI 251
           +     DSG  L C  + D  WI  G+VSW    G+ +FPG+YT  ++F  WI   V ++
Sbjct: 657 RDACKGDSGGPLSCRRKSDGKWILTGIVSWGHGSGRPNFPGVYTRVSNFVPWIHKYVPSL 716


>gi|148231605 ovochymase 2 [Homo sapiens]
          Length = 564

 Score =  118 bits (295), Expect = 7e-27
 Identities = 86/282 (30%), Positives = 122/282 (43%), Gaps = 53/282 (18%)

Query: 29  PWLRACGQT----------NVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWV 78
           P   +CGQ+          N+  R++ G  VE G +PWQVS+     +IC GS++  QWV
Sbjct: 28  PKAPSCGQSLVKVQPWNYFNIFSRILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWV 87

Query: 79  LTAAHCLQRFKDLSLYSVMVG---VHQRPENSTQLPLTRMVIHKDFSNL--MSQDIALLK 133
           +TAAHC+     +S  +V  G   + Q       L +  ++IH  FS    M  DIALLK
Sbjct: 88  ITAAHCIANRNIVSTLNVTAGEYDLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLK 147

Query: 134 LRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHP-DSVKSCCEFIREC 192
           +  +  +  FV P+CLP ++ +   G +C   GWG   + G L+     V        EC
Sbjct: 148 MAGAFQFGHFVGPICLPELREQFEAGFICTTAGWGRLTEGGVLSQVLQEVNLPILTWEEC 207

Query: 193 FQFTLTV------------------------DSGSSLVCQMDK-TWIQIGVVSWSFSCGQ 227
               LT+                        DSG SL+C+  K  W   GV SW   CG+
Sbjct: 208 VAALLTLKRPISGKTFLCTGFPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGR 267

Query: 228 ----------RHFPGIYTSTAHFNQWIRTEV--ANIRFISRA 257
                     +  PGI+T  +    WI   +   N R  SRA
Sbjct: 268 GWRNNVRKSDQGSPGIFTDISKVLPWIHEHIQTGNRRKSSRA 309


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.137    0.460 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,327,084
Number of Sequences: 37866
Number of extensions: 475969
Number of successful extensions: 1759
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 167
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1230
Number of HSP's gapped (non-prelim): 267
length of query: 282
length of database: 18,247,518
effective HSP length: 101
effective length of query: 181
effective length of database: 14,423,052
effective search space: 2610572412
effective search space used: 2610572412
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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