Search of human proteins with 239753543

Search of human proteins with 239753543

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239753543 PREDICTED: similar to hCG2041108 [Homo sapiens]
         (299 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239753543 PREDICTED: similar to hCG2041108 [Homo sapiens]          623   e-179
gi|239748119 PREDICTED: similar to hCG2041108 [Homo sapiens]          623   e-179
gi|239742018 PREDICTED: similar to hCG2041108 [Homo sapiens]          623   e-179
gi|33186882 testis serine protease 2 [Homo sapiens]                   226   1e-59
gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens]          216   3e-56
gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo ...   216   3e-56
gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo ...   216   3e-56
gi|23957702 transmembrane protease, serine 6 [Homo sapiens]           130   1e-30
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]             127   9e-30
gi|4506153 prostasin preproprotein [Homo sapiens]                     125   6e-29
gi|13994276 marapsin [Homo sapiens]                                   123   2e-28
gi|15559207 elastase 2A preproprotein [Homo sapiens]                  121   7e-28
gi|21614531 testisin isoform 2 [Homo sapiens]                         119   2e-27
gi|58331211 elastase 2B preproprotein [Homo sapiens]                  119   3e-27
gi|116256363 transmembrane protease, serine 13 [Homo sapiens]         119   3e-27
gi|5803197 testisin isoform 1 [Homo sapiens]                          119   3e-27
gi|205360905 testis-specific serine protease 1 [Homo sapiens]         118   7e-27
gi|4503627 coagulation factor XI precursor [Homo sapiens]             117   9e-27
gi|117956391 protease, serine, 33 [Homo sapiens]                      117   2e-26
gi|110815798 ovochymase 1 [Homo sapiens]                              113   2e-25
gi|32698940 transmembrane protease, serine 12 [Homo sapiens]          112   3e-25
gi|62526043 chymotrypsin C preproprotein [Homo sapiens]               111   7e-25
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]      110   1e-24
gi|21614533 testisin isoform 3 [Homo sapiens]                         110   2e-24
gi|4758508 transmembrane protease, serine 11D [Homo sapiens]          110   2e-24
gi|68508970 tryptase beta 2 precursor [Homo sapiens]                  110   2e-24
gi|223942069 enterokinase precursor [Homo sapiens]                    108   4e-24
gi|148231605 ovochymase 2 [Homo sapiens]                              108   4e-24
gi|34098976 marapsin 2 [Homo sapiens]                                 108   6e-24
gi|148806900 epidermis-specific serine protease-like protein [Ho...   108   7e-24

>gi|239753543 PREDICTED: similar to hCG2041108 [Homo sapiens]
          Length = 299

 Score =  623 bits (1606), Expect = e-179
 Identities = 299/299 (100%), Positives = 299/299 (100%)

Query: 1   MASQSGSSLGLLAWFLLLQPWLEEARAGRVGAQGGVALLFPSALPSGPGGQDPGASGWEP 60
           MASQSGSSLGLLAWFLLLQPWLEEARAGRVGAQGGVALLFPSALPSGPGGQDPGASGWEP
Sbjct: 1   MASQSGSSLGLLAWFLLLQPWLEEARAGRVGAQGGVALLFPSALPSGPGGQDPGASGWEP 60

Query: 61  PPVGAPGSPAAPQSRGNAVRPASVLLPSACGQRTSRITGGLPAPDRKWPWQVSLQTSNRH 120
           PPVGAPGSPAAPQSRGNAVRPASVLLPSACGQRTSRITGGLPAPDRKWPWQVSLQTSNRH
Sbjct: 61  PPVGAPGSPAAPQSRGNAVRPASVLLPSACGQRTSRITGGLPAPDRKWPWQVSLQTSNRH 120

Query: 121 ICGGSLIARHWVLTAAHCISGVDPGGSSCSHLEYTVKLGDTNVHHRSKTALVVPVRDVVI 180
           ICGGSLIARHWVLTAAHCISGVDPGGSSCSHLEYTVKLGDTNVHHRSKTALVVPVRDVVI
Sbjct: 121 ICGGSLIARHWVLTAAHCISGVDPGGSSCSHLEYTVKLGDTNVHHRSKTALVVPVRDVVI 180

Query: 181 HRYFTSPGIIENDIALALLDFPVNYSTHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEK 240
           HRYFTSPGIIENDIALALLDFPVNYSTHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEK
Sbjct: 181 HRYFTSPGIIENDIALALLDFPVNYSTHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEK 240

Query: 241 IVTEPQEAELSIILHDKCNEVLKEKIRMRSEMVKKGTICGYNDQGKDACQILGGPWSVN 299
           IVTEPQEAELSIILHDKCNEVLKEKIRMRSEMVKKGTICGYNDQGKDACQILGGPWSVN
Sbjct: 241 IVTEPQEAELSIILHDKCNEVLKEKIRMRSEMVKKGTICGYNDQGKDACQILGGPWSVN 299


>gi|239748119 PREDICTED: similar to hCG2041108 [Homo sapiens]
          Length = 299

 Score =  623 bits (1606), Expect = e-179
 Identities = 299/299 (100%), Positives = 299/299 (100%)

Query: 1   MASQSGSSLGLLAWFLLLQPWLEEARAGRVGAQGGVALLFPSALPSGPGGQDPGASGWEP 60
           MASQSGSSLGLLAWFLLLQPWLEEARAGRVGAQGGVALLFPSALPSGPGGQDPGASGWEP
Sbjct: 1   MASQSGSSLGLLAWFLLLQPWLEEARAGRVGAQGGVALLFPSALPSGPGGQDPGASGWEP 60

Query: 61  PPVGAPGSPAAPQSRGNAVRPASVLLPSACGQRTSRITGGLPAPDRKWPWQVSLQTSNRH 120
           PPVGAPGSPAAPQSRGNAVRPASVLLPSACGQRTSRITGGLPAPDRKWPWQVSLQTSNRH
Sbjct: 61  PPVGAPGSPAAPQSRGNAVRPASVLLPSACGQRTSRITGGLPAPDRKWPWQVSLQTSNRH 120

Query: 121 ICGGSLIARHWVLTAAHCISGVDPGGSSCSHLEYTVKLGDTNVHHRSKTALVVPVRDVVI 180
           ICGGSLIARHWVLTAAHCISGVDPGGSSCSHLEYTVKLGDTNVHHRSKTALVVPVRDVVI
Sbjct: 121 ICGGSLIARHWVLTAAHCISGVDPGGSSCSHLEYTVKLGDTNVHHRSKTALVVPVRDVVI 180

Query: 181 HRYFTSPGIIENDIALALLDFPVNYSTHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEK 240
           HRYFTSPGIIENDIALALLDFPVNYSTHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEK
Sbjct: 181 HRYFTSPGIIENDIALALLDFPVNYSTHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEK 240

Query: 241 IVTEPQEAELSIILHDKCNEVLKEKIRMRSEMVKKGTICGYNDQGKDACQILGGPWSVN 299
           IVTEPQEAELSIILHDKCNEVLKEKIRMRSEMVKKGTICGYNDQGKDACQILGGPWSVN
Sbjct: 241 IVTEPQEAELSIILHDKCNEVLKEKIRMRSEMVKKGTICGYNDQGKDACQILGGPWSVN 299


>gi|239742018 PREDICTED: similar to hCG2041108 [Homo sapiens]
          Length = 299

 Score =  623 bits (1606), Expect = e-179
 Identities = 299/299 (100%), Positives = 299/299 (100%)

Query: 1   MASQSGSSLGLLAWFLLLQPWLEEARAGRVGAQGGVALLFPSALPSGPGGQDPGASGWEP 60
           MASQSGSSLGLLAWFLLLQPWLEEARAGRVGAQGGVALLFPSALPSGPGGQDPGASGWEP
Sbjct: 1   MASQSGSSLGLLAWFLLLQPWLEEARAGRVGAQGGVALLFPSALPSGPGGQDPGASGWEP 60

Query: 61  PPVGAPGSPAAPQSRGNAVRPASVLLPSACGQRTSRITGGLPAPDRKWPWQVSLQTSNRH 120
           PPVGAPGSPAAPQSRGNAVRPASVLLPSACGQRTSRITGGLPAPDRKWPWQVSLQTSNRH
Sbjct: 61  PPVGAPGSPAAPQSRGNAVRPASVLLPSACGQRTSRITGGLPAPDRKWPWQVSLQTSNRH 120

Query: 121 ICGGSLIARHWVLTAAHCISGVDPGGSSCSHLEYTVKLGDTNVHHRSKTALVVPVRDVVI 180
           ICGGSLIARHWVLTAAHCISGVDPGGSSCSHLEYTVKLGDTNVHHRSKTALVVPVRDVVI
Sbjct: 121 ICGGSLIARHWVLTAAHCISGVDPGGSSCSHLEYTVKLGDTNVHHRSKTALVVPVRDVVI 180

Query: 181 HRYFTSPGIIENDIALALLDFPVNYSTHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEK 240
           HRYFTSPGIIENDIALALLDFPVNYSTHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEK
Sbjct: 181 HRYFTSPGIIENDIALALLDFPVNYSTHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEK 240

Query: 241 IVTEPQEAELSIILHDKCNEVLKEKIRMRSEMVKKGTICGYNDQGKDACQILGGPWSVN 299
           IVTEPQEAELSIILHDKCNEVLKEKIRMRSEMVKKGTICGYNDQGKDACQILGGPWSVN
Sbjct: 241 IVTEPQEAELSIILHDKCNEVLKEKIRMRSEMVKKGTICGYNDQGKDACQILGGPWSVN 299


>gi|33186882 testis serine protease 2 [Homo sapiens]
          Length = 293

 Score =  226 bits (577), Expect = 1e-59
 Identities = 119/289 (41%), Positives = 173/289 (59%), Gaps = 27/289 (9%)

Query: 3   SQSGSSLGLLAWFLLLQPWLEEARAGRVGAQGGVALLFPSALPSGPGGQDPGASGWEPPP 62
           S  G S GLLAW LLLQPW  +  AG    +       PS L S  GG++P AS      
Sbjct: 2   SSGGGSRGLLAWLLLLQPWPGQNWAGMAAPR------LPSPLLSEEGGENPEASP----- 50

Query: 63  VGAPGSPAAPQSRGNAVRPASVLLPSACGQRTSRITGGLPAPDRKWPWQVSLQTSNRHIC 122
             APG  A P        P   LL   CG+   RI GG+ A + +WPWQVS++T  RHIC
Sbjct: 51  --APGPEAGPPLNLFTSFPGDSLL---CGRTPLRIVGGVDAEEGRWPWQVSVRTKGRHIC 105

Query: 123 GGSLIARHWVLTAAHCISGVDPGGSSCSHLEYTVKLGDTNVHHRSKTALVVPVRDVVIHR 182
           GG+L+   WVLTA HCIS         S   Y+VK+GD +V++ + T++VV V+   +H 
Sbjct: 106 GGTLVTATWVLTAGHCIS---------SRFHYSVKMGDRSVYNEN-TSVVVSVQRAFVHP 155

Query: 183 YFTSPGIIENDIALALLDFPVNYSTHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEKIV 242
            F++   I ND+AL  L  PVN++++IQ +C+P++ F V+  T CWVTGWGK  E EK+ 
Sbjct: 156 KFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCWVTGWGKTPEREKLA 215

Query: 243 TE-PQEAELSIILHDKCNEVLKEKIRMRSEMVKKGTICGYNDQGKDACQ 290
           +E  Q+ +  I+ +++CN+++++ +    +++ KG +CGY +QGKD+CQ
Sbjct: 216 SEILQDVDQYIMCYEECNKIIQKALSSTKDVIIKGMVCGYKEQGKDSCQ 264


>gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens]
          Length = 410

 Score =  216 bits (549), Expect = 3e-56
 Identities = 152/380 (40%), Positives = 184/380 (48%), Gaps = 112/380 (29%)

Query: 1   MASQSGS---------SLGLLAWFLLLQPWLEEARAGRVGAQ------------------ 33
           MASQ G          SL LL W   LQP L EA +G+ GA                   
Sbjct: 1   MASQDGLRRGRGGTRLSLHLLIWLQFLQPLLSEAGSGQGGAGLHPRWVWGGSGGAVGTGR 60

Query: 34  --GGVALLFP--SALPSGPGG---------QDPGASGWEPPPVG-----------APGSP 69
             GG A   P     PS PG            P +      PV            APGSP
Sbjct: 61  RGGGAARPAPVRRGSPSSPGEPYRPEEDSRMTPASPEARTSPVHPKFPKIPETSVAPGSP 120

Query: 70  AAPQSRGNAVRPASVL---------------LPSACGQRTSRITGGLPAPDRKWPWQVSL 114
           A     G+ V  AS +                  ACG R SR+ GGLPAP++KWPWQVSL
Sbjct: 121 ATAGPPGSWVTSASTVGEALESDGISDLGRQFSQACGHRVSRMIGGLPAPNKKWPWQVSL 180

Query: 115 QTSNRHICGGSLIARHWVLTAAHCI-------------SGVDPGGSSCSHLEYTVKLGDT 161
           QTSN H CGGSLI R WVLTAAHC+             +G+     +  HLE        
Sbjct: 181 QTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIGRWDQAWKHLE-------- 232

Query: 162 NVHHRSKTALVVPVRDVVIHRYFTSPGIIENDIALALLDFPVNYSTHIQLVCLPEQAFMV 221
                          D++    F     + +DIALALL + VNYS+HIQ  CLPE+ F V
Sbjct: 233 ---------------DIIFPSNFDF-ATLTSDIALALLAYSVNYSSHIQPACLPEKLFEV 276

Query: 222 QAGTNCWVTGWGKVNETEKIVTEP-----QEAELSIILHDKCNEVLKEKIRMRSEMVKKG 276
           +AGT CWVTGWG+V+E+   V+ P     QE EL+I+ H+KC E+LK K   +S+MV +G
Sbjct: 277 EAGTECWVTGWGQVSES---VSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTRG 333

Query: 277 TICGYNDQGKDACQ-ILGGP 295
           T+CGYNDQGKDACQ   GGP
Sbjct: 334 TVCGYNDQGKDACQGDSGGP 353


>gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo
           sapiens]
          Length = 410

 Score =  216 bits (549), Expect = 3e-56
 Identities = 152/380 (40%), Positives = 184/380 (48%), Gaps = 112/380 (29%)

Query: 1   MASQSGS---------SLGLLAWFLLLQPWLEEARAGRVGAQ------------------ 33
           MASQ G          SL LL W   LQP L EA +G+ GA                   
Sbjct: 1   MASQDGLRRGRGGTRLSLHLLIWLQFLQPLLSEAGSGQGGAGLHPRWVWGGSGGAVGTGR 60

Query: 34  --GGVALLFP--SALPSGPGG---------QDPGASGWEPPPVG-----------APGSP 69
             GG A   P     PS PG            P +      PV            APGSP
Sbjct: 61  RGGGAARPAPVRRGSPSSPGEPYRPEEDSRMTPASPEARTSPVHPKFPKIPETSVAPGSP 120

Query: 70  AAPQSRGNAVRPASVL---------------LPSACGQRTSRITGGLPAPDRKWPWQVSL 114
           A     G+ V  AS +                  ACG R SR+ GGLPAP++KWPWQVSL
Sbjct: 121 ATAGPPGSWVTSASTVGEALESDGISDLGRQFSQACGHRVSRMIGGLPAPNKKWPWQVSL 180

Query: 115 QTSNRHICGGSLIARHWVLTAAHCI-------------SGVDPGGSSCSHLEYTVKLGDT 161
           QTSN H CGGSLI R WVLTAAHC+             +G+     +  HLE        
Sbjct: 181 QTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIGRWDQAWKHLE-------- 232

Query: 162 NVHHRSKTALVVPVRDVVIHRYFTSPGIIENDIALALLDFPVNYSTHIQLVCLPEQAFMV 221
                          D++    F     + +DIALALL + VNYS+HIQ  CLPE+ F V
Sbjct: 233 ---------------DIIFPSNFDF-ATLTSDIALALLAYSVNYSSHIQPACLPEKLFEV 276

Query: 222 QAGTNCWVTGWGKVNETEKIVTEP-----QEAELSIILHDKCNEVLKEKIRMRSEMVKKG 276
           +AGT CWVTGWG+V+E+   V+ P     QE EL+I+ H+KC E+LK K   +S+MV +G
Sbjct: 277 EAGTECWVTGWGQVSES---VSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTRG 333

Query: 277 TICGYNDQGKDACQ-ILGGP 295
           T+CGYNDQGKDACQ   GGP
Sbjct: 334 TVCGYNDQGKDACQGDSGGP 353


>gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo
           sapiens]
          Length = 410

 Score =  216 bits (549), Expect = 3e-56
 Identities = 152/380 (40%), Positives = 184/380 (48%), Gaps = 112/380 (29%)

Query: 1   MASQSGS---------SLGLLAWFLLLQPWLEEARAGRVGAQ------------------ 33
           MASQ G          SL LL W   LQP L EA +G+ GA                   
Sbjct: 1   MASQDGLRRGRGGTRLSLHLLIWLQFLQPLLSEAGSGQGGAGLHPRWVWGGSGGAVGTGR 60

Query: 34  --GGVALLFP--SALPSGPGG---------QDPGASGWEPPPVG-----------APGSP 69
             GG A   P     PS PG            P +      PV            APGSP
Sbjct: 61  RGGGAARPAPVRRGSPSSPGEPYRPEEDSRMTPASPEARTSPVHPKFPKIPETSVAPGSP 120

Query: 70  AAPQSRGNAVRPASVL---------------LPSACGQRTSRITGGLPAPDRKWPWQVSL 114
           A     G+ V  AS +                  ACG R SR+ GGLPAP++KWPWQVSL
Sbjct: 121 ATAGPPGSWVTSASTVGEALESDGISDLGRQFSQACGHRVSRMIGGLPAPNKKWPWQVSL 180

Query: 115 QTSNRHICGGSLIARHWVLTAAHCI-------------SGVDPGGSSCSHLEYTVKLGDT 161
           QTSN H CGGSLI R WVLTAAHC+             +G+     +  HLE        
Sbjct: 181 QTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIGRWDQAWKHLE-------- 232

Query: 162 NVHHRSKTALVVPVRDVVIHRYFTSPGIIENDIALALLDFPVNYSTHIQLVCLPEQAFMV 221
                          D++    F     + +DIALALL + VNYS+HIQ  CLPE+ F V
Sbjct: 233 ---------------DIIFPSNFDF-ATLTSDIALALLAYSVNYSSHIQPACLPEKLFEV 276

Query: 222 QAGTNCWVTGWGKVNETEKIVTEP-----QEAELSIILHDKCNEVLKEKIRMRSEMVKKG 276
           +AGT CWVTGWG+V+E+   V+ P     QE EL+I+ H+KC E+LK K   +S+MV +G
Sbjct: 277 EAGTECWVTGWGQVSES---VSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTRG 333

Query: 277 TICGYNDQGKDACQ-ILGGP 295
           T+CGYNDQGKDACQ   GGP
Sbjct: 334 TVCGYNDQGKDACQGDSGGP 353


>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
          Length = 811

 Score =  130 bits (328), Expect = 1e-30
 Identities = 78/209 (37%), Positives = 110/209 (52%), Gaps = 14/209 (6%)

Query: 90  CGQR--TSRITGGLPAPDRKWPWQVSLQTSNRHICGGSLIARHWVLTAAHCISGVDPGGS 147
           CG +  +SRI GG  + + +WPWQ SLQ   RHICGG+LIA  WV+TAAHC        S
Sbjct: 568 CGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQ----EDS 623

Query: 148 SCSHLEYTVKLGDTNVHHRSKTALVVPVRDVVIHRYFTSPGIIENDIALALLDFPVNYST 207
             S + +TV LG    + R    +   V  +++H Y       + D+AL  LD PV  S 
Sbjct: 624 MASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDS-HDYDVALLQLDHPVVRSA 682

Query: 208 HIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEKIVTEPQEAELSIILHDKCNEVLKEKIR 267
            ++ VCLP ++   + G +CW+TGWG + E   I    Q+ ++ +I  D C+EV + ++ 
Sbjct: 683 AVRPVCLPARSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYRYQVT 742

Query: 268 MRSEMVKKGTICGYNDQGKDACQ-ILGGP 295
            R          GY    KDACQ   GGP
Sbjct: 743 PRM------LCAGYRKGKKDACQGDSGGP 765


>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
          Length = 638

 Score =  127 bits (320), Expect = 9e-30
 Identities = 81/229 (35%), Positives = 121/229 (52%), Gaps = 21/229 (9%)

Query: 74  SRGNAVRPASVLLPSACGQRTS-RITGGLPAPDRKWPWQVSLQ---TSNRHICGGSLIAR 129
           S G ++R  +    S C  +TS RI GG  +   +WPWQVSLQ   T+ RH+CGGSLI  
Sbjct: 367 SSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGH 426

Query: 130 HWVLTAAHCISGVDPGGSSCSHLEYTVKLGDTNVHHRSKTALVVPVRDVVIHR-YFTSPG 188
            WVLTAAHC  G+           + +  G  N+   +K      +++++IH+ Y  S G
Sbjct: 427 QWVLTAAHCFDGLPLQDV------WRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEG 480

Query: 189 IIENDIALALLDFPVNYSTHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEKIVTEPQEA 248
              +DIAL  L  P+NY+   + +CLP +       TNCWVTGWG   E  +I    Q+ 
Sbjct: 481 --NHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKV 538

Query: 249 ELSIILHDKCNEVLKEKIRMRSEMVKKGTIC-GYNDQGKDACQ-ILGGP 295
            + ++ +++C +      R +   + +  +C GY + GKDAC+   GGP
Sbjct: 539 NIPLVTNEECQK------RYQDYKITQRMVCAGYKEGGKDACKGDSGGP 581


>gi|4506153 prostasin preproprotein [Homo sapiens]
          Length = 343

 Score =  125 bits (313), Expect = 6e-29
 Identities = 78/209 (37%), Positives = 112/209 (53%), Gaps = 14/209 (6%)

Query: 95  SRITGGLPAPDRKWPWQVSLQTSNRHICGGSLIARHWVLTAAHCISGVDPGGSSCSHLE- 153
           +RITGG  A   +WPWQVS+     H+CGGSL++  WVL+AAHC         S  H E 
Sbjct: 43  ARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCF-------PSEHHKEA 95

Query: 154 YTVKLGDTNVHHRSKTALVVPVRDVVIHRYFTSPGIIENDIALALLDFPVNYSTHIQLVC 213
           Y VKLG   +   S+ A V  ++D++ H  +   G  + DIAL  L  P+ +S +I+ +C
Sbjct: 96  YEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEG-SQGDIALLQLSRPITFSRYIRPIC 154

Query: 214 LPEQAFMVQAGTNCWVTGWGKVNETEKIVTEP--QEAELSIILHDKCNEVLKEKIRMRS- 270
           LP        G +C VTGWG V  +  ++T    Q+ E+ +I  + CN +     +    
Sbjct: 155 LPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEP 214

Query: 271 EMVKKGTIC-GYNDQGKDACQ-ILGGPWS 297
             V++  +C GY + GKDACQ   GGP S
Sbjct: 215 HFVQEDMVCAGYVEGGKDACQGDSGGPLS 243


>gi|13994276 marapsin [Homo sapiens]
          Length = 290

 Score =  123 bits (309), Expect = 2e-28
 Identities = 77/217 (35%), Positives = 113/217 (52%), Gaps = 17/217 (7%)

Query: 88  SACGQ--RTSRITGGLPAPDRKWPWQVSLQTSNRHICGGSLIARHWVLTAAHCISGVDPG 145
           +ACG+    +R+ GG    + +WPWQVS+Q +  H CGGSLIA  WVLTAAHC       
Sbjct: 24  TACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSET 83

Query: 146 GSSCSHLEYTVKLGDTNVHHRSKTALVVPVRDVVIHRYFTSPGIIENDIALALLDFPVNY 205
                   Y V LG   +      A+   VR V  +  +        D+AL  L+ PV +
Sbjct: 84  SL------YQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTA-SSADVALVELEAPVPF 136

Query: 206 STHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEKIVTEP---QEAELSIILHDKCNEVL 262
           + +I  VCLP+ + + + G NCWVTGWG  +E E ++ EP   Q+  + II   KCN + 
Sbjct: 137 TNYILPVCLPDPSVIFETGMNCWVTGWGSPSE-EDLLPEPRILQKLAVPIIDTPKCNLLY 195

Query: 263 KE--KIRMRSEMVKKGTIC-GYNDQGKDACQ-ILGGP 295
            +  +   + + +K   +C G+ +  KDAC+   GGP
Sbjct: 196 SKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGP 232


>gi|15559207 elastase 2A preproprotein [Homo sapiens]
          Length = 269

 Score =  121 bits (304), Expect = 7e-28
 Identities = 79/226 (34%), Positives = 111/226 (49%), Gaps = 24/226 (10%)

Query: 89  ACGQRT-----SRITGGLPAPDRKWPWQVSLQTSNR----HICGGSLIARHWVLTAAHCI 139
           +CG  T     +R+ GG  A    WPWQVSLQ S+     H CGGSLIA  WVLTAAHCI
Sbjct: 16  SCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHCI 75

Query: 140 SGVDPGGSSCSHLEYTVKLGDTNVHHRSKTALVVPVRDVVIHRYFTSPGIIE-NDIALAL 198
           S         S   Y V LG  N++     +L V V  +V+H+ + S  I + NDIAL  
Sbjct: 76  S---------SSRTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALLK 126

Query: 199 LDFPVNYSTHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEKIVTEPQEAELSIILHDKC 258
           L  PV+ +  IQL CLP    ++     C+VTGWG++     +    Q+  L ++ +  C
Sbjct: 127 LANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLVVDYATC 186

Query: 259 NEVLKEKIRMRSEMVKKG-----TICGYNDQGKDACQILGGPWSVN 299
           +        +++ M+  G     + C  +  G   CQ   G W V+
Sbjct: 187 SSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVH 232


>gi|21614531 testisin isoform 2 [Homo sapiens]
          Length = 312

 Score =  119 bits (299), Expect = 2e-27
 Identities = 81/224 (36%), Positives = 109/224 (48%), Gaps = 19/224 (8%)

Query: 86  LPSACGQR--TSRITGGLPAPDRKWPWQVSLQTSNRHICGGSLIARHWVLTAAHCISG-- 141
           L   CG+R  TSRI GG  A   +WPWQ SL+  + H+CG SL++  W LTAAHC     
Sbjct: 29  LSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETDL 88

Query: 142 VDPGGSSCSHLEYTVKLGDTNVHHRSKTALVVPVRDVVIHRYFTSPGIIEN---DIALAL 198
            DP G       + V+ G       S  +L        +   + SP  + N   DIAL  
Sbjct: 89  SDPSG-------WMVQFGQL-TSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVK 140

Query: 199 LDFPVNYSTHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEKIVTEP--QEAELSIILHD 256
           L  PV Y+ HIQ +CL    F  +  T+CWVTGWG + E E + +    QE +++II + 
Sbjct: 141 LSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNS 200

Query: 257 KCNEVLKEKIRMRSEMVKKGTICGYNDQGKDAC-QILGGPWSVN 299
            CN +   K   R ++       G    GKDAC    GGP + N
Sbjct: 201 MCNHLFL-KYSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACN 243


>gi|58331211 elastase 2B preproprotein [Homo sapiens]
          Length = 269

 Score =  119 bits (298), Expect = 3e-27
 Identities = 80/226 (35%), Positives = 112/226 (49%), Gaps = 24/226 (10%)

Query: 89  ACGQRT-----SRITGGLPAPDRKWPWQVSLQTSNR----HICGGSLIARHWVLTAAHCI 139
           +CG  T     SR+ GG  A    WPWQVSLQ S+     H CGGSLIA  WVLTAAHCI
Sbjct: 16  SCGVSTYAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHCI 75

Query: 140 SGVDPGGSSCSHLEYTVKLGDTNVHHRSKTALVVPVRDVVIHRYFTSPGIIE-NDIALAL 198
           S         S   Y V LG  N++     +L V V  +V+H+ + S  + + NDIAL  
Sbjct: 76  S---------SSGIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGNDIALLK 126

Query: 199 LDFPVNYSTHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEKIVTEPQEAELSIILHDKC 258
           L  PV+ +  IQL CLP    ++     C+VTGWG++     +  + ++  L ++ +  C
Sbjct: 127 LANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRLLVVDYATC 186

Query: 259 NEVLKEKIRMRSEMV---KKGTICGYNDQ--GKDACQILGGPWSVN 299
           +        +++ M+     G IC  N    G   CQ   G W V+
Sbjct: 187 SSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVH 232


>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
          Length = 567

 Score =  119 bits (298), Expect = 3e-27
 Identities = 81/214 (37%), Positives = 108/214 (50%), Gaps = 20/214 (9%)

Query: 88  SACGQR--TSRITGGLPAPDRKWPWQVSLQTSNRHICGGSLIARHWVLTAAHCISGVDPG 145
           S CG R  T RI GG  A D KWPWQVSL     HICGG+LI   WVLTAAHC       
Sbjct: 315 SHCGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTRE- 373

Query: 146 GSSCSHLE-YTVKLGDTNVHHRSKTALVVPVRDVVIHRYFTSPGIIENDIALALLDFPVN 204
                 LE + V  G +N+H   + A    + +++I+  +T     + DIAL  L  P+ 
Sbjct: 374 ----KVLEGWKVYAGTSNLHQLPEAA---SIAEIIINSNYTDEE-DDYDIALMRLSKPLT 425

Query: 205 YSTHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEKIVTEP--QEAELSIILHDKCNEVL 262
            S HI   CLP           CW+TG+GK  ET+   T P  +E ++++I   KCN+ L
Sbjct: 426 LSAHIHPACLPMHGQTFSLNETCWITGFGKTRETDD-KTSPFLREVQVNLIDFKKCNDYL 484

Query: 263 KEKIRMRSEMVKKGTICGYNDQGKDACQ-ILGGP 295
                +   M+  G + G    G+D+CQ   GGP
Sbjct: 485 VYDSYLTPRMMCAGDLRG----GRDSCQGDSGGP 514


>gi|5803197 testisin isoform 1 [Homo sapiens]
          Length = 314

 Score =  119 bits (298), Expect = 3e-27
 Identities = 81/226 (35%), Positives = 109/226 (48%), Gaps = 21/226 (9%)

Query: 86  LPSACGQR--TSRITGGLPAPDRKWPWQVSLQTSNRHICGGSLIARHWVLTAAHCISGV- 142
           L   CG+R  TSRI GG  A   +WPWQ SL+  + H+CG SL++  W LTAAHC     
Sbjct: 29  LSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYS 88

Query: 143 ---DPGGSSCSHLEYTVKLGDTNVHHRSKTALVVPVRDVVIHRYFTSPGIIEN---DIAL 196
              DP G       + V+ G       S  +L        +   + SP  + N   DIAL
Sbjct: 89  DLSDPSG-------WMVQFGQL-TSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIAL 140

Query: 197 ALLDFPVNYSTHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEKIVTEP--QEAELSIIL 254
             L  PV Y+ HIQ +CL    F  +  T+CWVTGWG + E E + +    QE +++II 
Sbjct: 141 VKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIIN 200

Query: 255 HDKCNEVLKEKIRMRSEMVKKGTICGYNDQGKDAC-QILGGPWSVN 299
           +  CN +   K   R ++       G    GKDAC    GGP + N
Sbjct: 201 NSMCNHLFL-KYSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACN 245


>gi|205360905 testis-specific serine protease 1 [Homo sapiens]
          Length = 318

 Score =  118 bits (295), Expect = 7e-27
 Identities = 82/245 (33%), Positives = 127/245 (51%), Gaps = 22/245 (8%)

Query: 63  VGAPGSPAAPQSR-GNAVRPASVLLPSACGQRT--SRITGGLPAPDRKWPWQVSLQTSNR 119
           +G PG   A Q+  G A RP       ACG R   + + GG+ +   +WPWQ SL+   R
Sbjct: 18  LGKPGELGALQAGPGAARRPGGGGREEACGHREIHALVAGGVESARGRWPWQASLRLRRR 77

Query: 120 HICGGSLIARHWVLTAAHCISGVDPGGSSCSHLEYTVKLGD-----TNVHHRSKTALVVP 174
           H CGGSL++R WVL+AAHC              E+TV+LG+     T  + R+ ++    
Sbjct: 78  HRCGGSLLSRRWVLSAAHCFQ------KHYYPSEWTVQLGELTSRPTPWNLRAYSSR-YK 130

Query: 175 VRDVVIHRYFTSPGIIENDIALALLDFPVNYSTHIQLVCLPEQAFMVQAGTNCWVTGWGK 234
           V+D++++    + G++ NDIAL  L   V Y+ +IQ +C+    F      +CWVTGWG 
Sbjct: 131 VQDIIVNP--DALGVLRNDIALLRLASSVTYNAYIQPICIESSTFNFVHRPDCWVTGWGL 188

Query: 235 VNETEKIVTEP---QEAELSIILHDKCNEVLKEKIRMRSEMVKKGTICGYNDQGKDACQ- 290
           ++ +   +  P   +EA+++I+ + +CN  L E+   RS +       G  D   D C+ 
Sbjct: 189 ISPSGTPLPPPYNLREAQVTILNNTRCN-YLFEQPSSRSMIWDSMFCAGAEDGSVDTCKG 247

Query: 291 ILGGP 295
             GGP
Sbjct: 248 DSGGP 252


>gi|4503627 coagulation factor XI precursor [Homo sapiens]
          Length = 625

 Score =  117 bits (294), Expect = 9e-27
 Identities = 74/209 (35%), Positives = 110/209 (52%), Gaps = 22/209 (10%)

Query: 96  RITGGLPAPDRKWPWQVSLQTSN---RHICGGSLIARHWVLTAAHCISGVDPGGSSCSHL 152
           RI GG  +   +WPWQV+L T++   RH+CGGS+I   W+LTAAHC  GV+      S  
Sbjct: 387 RIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVE------SPK 440

Query: 153 EYTVKLGDTNVHHRSKTALVVPVRDVVIHRYFTSPGIIEN--DIALALLDFPVNYSTHIQ 210
              V  G  N     +      V++++IH  +    + E+  DIAL  L+  VNY+   +
Sbjct: 441 ILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYK---MAESGYDIALLKLETTVNYTDSQR 497

Query: 211 LVCLPEQAFMVQAGTNCWVTGWGKVNETEKIVTEPQEAELSIILHDKCNEVLKEKIRMRS 270
            +CLP +       T+CWVTGWG     +KI    Q+A++ ++ +++C +      R R 
Sbjct: 498 PICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQK------RYRG 551

Query: 271 EMVKKGTIC-GYNDQGKDACQ-ILGGPWS 297
             +    IC GY + GKDAC+   GGP S
Sbjct: 552 HKITHKMICAGYREGGKDACKGDSGGPLS 580


>gi|117956391 protease, serine, 33 [Homo sapiens]
          Length = 280

 Score =  117 bits (292), Expect = 2e-26
 Identities = 80/216 (37%), Positives = 105/216 (48%), Gaps = 15/216 (6%)

Query: 88  SACGQ--RTSRITGGLPAPDRKWPWQVSLQTSNRHICGGSLIARHWVLTAAHCISGVDPG 145
           +ACGQ   +SRI GG    D +WPWQ S+Q    H+CGGSLIA  WVLTAAHC       
Sbjct: 26  AACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFP----- 80

Query: 146 GSSCSHLEYTVKLGDTNVHHRSKTALVVPVRDVVIHRYFTSPGIIENDIALALLDFPVNY 205
                  EY V+LG   +   S   L VPVR V++   ++  G    D+AL  L  PV  
Sbjct: 81  -RRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDG-ARGDLALLQLRRPVPL 138

Query: 206 STHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEKIV--TEPQEAELSIILHDKCNEV-- 261
           S  +Q VCLP        GT C VTGWG +     +      Q   + ++    C+ +  
Sbjct: 139 SARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYH 198

Query: 262 LKEKIRMRSEMVKKGTIC-GYNDQGKDACQ-ILGGP 295
           +   +     +V  G++C GY    KDACQ   GGP
Sbjct: 199 VGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGP 234


>gi|110815798 ovochymase 1 [Homo sapiens]
          Length = 1134

 Score =  113 bits (283), Expect = 2e-25
 Identities = 72/205 (35%), Positives = 102/205 (49%), Gaps = 17/205 (8%)

Query: 93  RTSRITGGLPAPDRKWPWQVSLQTSNRHICGGSLIARHWVLTAAHCISGVDPGGSSCSHL 152
           R S +TG         PWQVSL++   H CGGSLI    V+TAAHC+  +    S     
Sbjct: 51  RNSTVTGH--------PWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSL----SEKQLK 98

Query: 153 EYTVKLGDTNVHHRSKTALVVPVRDVVIHRYFTSPGIIENDIALALLDFPVNYSTHIQLV 212
             TV  G+ ++  + K    +PV  ++ H  + S   +  DIAL  L   V +   +Q +
Sbjct: 99  NITVTSGEYSLFQKDKQEQNIPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPI 158

Query: 213 CLPEQAFMVQAGTNCWVTGWGKVNETEKIVTEPQEAELSIILHDKCNEVLKEKIRMRSEM 272
           CLP+    V+ G  C  +GWGK+++T +     QE EL I+    CN VLK    M    
Sbjct: 159 CLPDSDDKVEPGILCLSSGWGKISKTSEYSNVLQEMELPIMDDRACNTVLKS---MNLPP 215

Query: 273 VKKGTIC-GYNDQGKDACQ-ILGGP 295
           + +  +C G+ D G DACQ   GGP
Sbjct: 216 LGRTMLCAGFPDWGMDACQGDSGGP 240



 Score = 97.1 bits (240), Expect = 2e-20
 Identities = 65/230 (28%), Positives = 107/230 (46%), Gaps = 18/230 (7%)

Query: 75  RGNAVRPASVLLPSACG-------QRTSRITGGLPAPDRKWPWQVSLQTSNRHICGGSLI 127
           + N V     +L   CG         + RI GG  A    WPWQV L+    + CGG++I
Sbjct: 546 QNNPVSTVKAILHDVCGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRFLGDYQCGGAII 605

Query: 128 ARHWVLTAAHCISGVDPGGSSCSHLEYTVKLGDTNVHHRSKTALVVPVRDVVIHRYFTSP 187
              W+LTAAHC+          + L +T+  GD + + +  T  V   + +++H  F + 
Sbjct: 606 NPVWILTAAHCVQ------LKNNPLSWTIIAGDHDRNLKESTEQVRRAKHIIVHEDFNTL 659

Query: 188 GIIENDIALALLDFPVNYSTHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEKIVTEPQE 247
              ++DIAL  L  P+ Y++ ++ VCLP  A  + +   C VTGWG ++    + +  Q+
Sbjct: 660 S-YDSDIALIQLSSPLEYNSVVRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASRLQQ 718

Query: 248 AELSIILHDKCNEVLKEKIRMRSEMVKKGTICGYNDQG-KDACQ-ILGGP 295
            ++ ++  + C             + +K    G+   G KD CQ   GGP
Sbjct: 719 IQVHVLEREVCEHTYYS--AHPGGITEKMICAGFAASGEKDFCQGDSGGP 766


>gi|32698940 transmembrane protease, serine 12 [Homo sapiens]
          Length = 348

 Score =  112 bits (281), Expect = 3e-25
 Identities = 72/209 (34%), Positives = 101/209 (48%), Gaps = 21/209 (10%)

Query: 95  SRITGGLPAPDRKWPWQVSLQTSNR----HICGGSLIARHWVLTAAHCISGV-DPGGSSC 149
           SRI GG  A    WPW VSLQ        H+CGG+L+   WVLTAAHC     DP     
Sbjct: 76  SRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDASDP----- 130

Query: 150 SHLEYTVKLGDTNVHHRSKTALVVPVRDVVIHRYFTSPGIIENDIALALLDFPVNYSTHI 209
             L +T  +G  N+H R      + ++ ++IH  F     + NDIAL  L   V Y+ +I
Sbjct: 131 --LMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYV-NDIALFHLKKAVRYNDYI 187

Query: 210 QLVCLPEQAFMVQAG-TNCWVTGWGKVNETEKIVTEPQEAELSIILHDKCNEVLKEKIRM 268
           Q +CLP   F +  G T C+++GWG+  E        Q+AE+  I  + CN       R 
Sbjct: 188 QPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCNSE-----RS 242

Query: 269 RSEMVKKGTICGYNDQGK-DACQ-ILGGP 295
              ++   + C  ++ G  D C+   GGP
Sbjct: 243 YGGIIPNTSFCAGDEDGAFDTCRGDSGGP 271


>gi|62526043 chymotrypsin C preproprotein [Homo sapiens]
          Length = 268

 Score =  111 bits (278), Expect = 7e-25
 Identities = 77/239 (32%), Positives = 115/239 (48%), Gaps = 26/239 (10%)

Query: 76  GNAVRPASVLLPSACG------QRTSRITGGLPAPDRKWPWQVSLQTSN----RHICGGS 125
           G  V  A +   S+CG        ++R+ GG  A    WPWQ+SLQ       RH CGG+
Sbjct: 3   GITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGT 62

Query: 126 LIARHWVLTAAHCISGVDPGGSSCSHLEYTVKLGDTNVHHRSKT-ALVVPVRDVVIHRYF 184
           LIA ++VLTAAHCIS             Y V +G  N+    +  +L V V  + +H+ +
Sbjct: 63  LIASNFVLTAAHCISNTRT---------YRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRW 113

Query: 185 TSPGIIENDIALALLDFPVNYSTHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEKIVTE 244
            +  ++ NDIAL  L   V  S  IQ+ CLPE+  ++     C+VTGWG++     I  +
Sbjct: 114 NAL-LLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADK 172

Query: 245 PQEAELSIILHDKCNEVLKEKIRMRSEMVKKG-----TICGYNDQGKDACQILGGPWSV 298
            Q+    ++ H  C+ +     R++  MV  G     + C  +  G   CQ+  G W V
Sbjct: 173 LQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEV 231


>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
          Length = 321

 Score =  110 bits (276), Expect = 1e-24
 Identities = 63/165 (38%), Positives = 86/165 (52%), Gaps = 11/165 (6%)

Query: 96  RITGGLPAPDRKWPWQVSLQTSNRHICGGSLIARHWVLTAAHCISGVDPGGSSCSHLEYT 155
           RI GG  AP   WPWQ SL+    H+CGGSL++  WVLTAAHC SG      S +  +Y 
Sbjct: 37  RIVGGHAAPAGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSG------SLNSSDYQ 90

Query: 156 VKLGDTNVHHRSKTALVVPVRDVVIHRYFTSPGIIENDIALALLDFPVNYSTHIQLVCLP 215
           V LG+  +   + +     VR +++H   +       DIAL  L  PV  S+ I  VCLP
Sbjct: 91  VHLGELEI---TLSPHFSTVRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCLP 147

Query: 216 EQAFMVQAGTNCWVTGWGKVNETEKIVT--EPQEAELSIILHDKC 258
           E +     G  CWVTGWG   E E +      +E ++S++  + C
Sbjct: 148 EASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVKVSVVDTETC 192


>gi|21614533 testisin isoform 3 [Homo sapiens]
          Length = 300

 Score =  110 bits (275), Expect = 2e-24
 Identities = 69/187 (36%), Positives = 94/187 (50%), Gaps = 19/187 (10%)

Query: 86  LPSACGQR--TSRITGGLPAPDRKWPWQVSLQTSNRHICGGSLIARHWVLTAAHCISGV- 142
           L   CG+R  TSRI GG  A   +WPWQ SL+  + H+CG SL++  W LTAAHC     
Sbjct: 29  LSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYS 88

Query: 143 ---DPGGSSCSHLEYTVKLGDTNVHHRSKTALVVPVRDVVIHRYFTSPGIIEN---DIAL 196
              DP G       + V+ G       S  +L        +   + SP  + N   DIAL
Sbjct: 89  DLSDPSG-------WMVQFGQL-TSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIAL 140

Query: 197 ALLDFPVNYSTHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEKIVTEP--QEAELSIIL 254
             L  PV Y+ HIQ +CL    F  +  T+CWVTGWG + E E + +    QE +++II 
Sbjct: 141 VKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIIN 200

Query: 255 HDKCNEV 261
           +  CN +
Sbjct: 201 NSMCNHL 207


>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
          Length = 418

 Score =  110 bits (275), Expect = 2e-24
 Identities = 72/202 (35%), Positives = 101/202 (50%), Gaps = 18/202 (8%)

Query: 96  RITGGLPAPDRKWPWQVSLQTSNRHICGGSLIARHWVLTAAHCISGVDPGGSSCSHLEYT 155
           RI GG  A +  WPWQVSL+ +N H CGGSLI   W+LTAAHC        S+ +  ++ 
Sbjct: 186 RILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFR------SNSNPRDWI 239

Query: 156 VKLGDTNVHHRSKTALVVPVRDVVIHRYFTSPGIIENDIALALLDFPVNYSTHIQLVCLP 215
              G +    +    L + VR+++IH  + S    ENDIAL  L+  V ++  I  VCLP
Sbjct: 240 ATSGISTTFPK----LRMRVRNILIHNNYKS-ATHENDIALVRLENSVTFTKDIHSVCLP 294

Query: 216 EQAFMVQAGTNCWVTGWGKVNETEKIVTEPQEAELSIILHDKCNEVLKEKIRMRSEMVKK 275
                +  G+  +VTGWG        V E ++ ++ II +D CN          +  +  
Sbjct: 295 AATQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAP-----HSYNGAILS 349

Query: 276 GTIC-GYNDQGKDACQ-ILGGP 295
           G +C G    G DACQ   GGP
Sbjct: 350 GMLCAGVPQGGVDACQGDSGGP 371


>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
          Length = 275

 Score =  110 bits (274), Expect = 2e-24
 Identities = 76/219 (34%), Positives = 115/219 (52%), Gaps = 24/219 (10%)

Query: 89  ACGQRTSR--ITGGLPAPDRKWPWQVSLQTSNR---HICGGSLIARHWVLTAAHCISGVD 143
           A GQ   R  I GG  AP  KWPWQVSL+  +R   H CGGSLI   WVLTAAHC+    
Sbjct: 21  APGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCVG--- 77

Query: 144 PGGSSCSHLEYTVKLGDTNVHHRSKTALVVPVRDVVIHRYFTSPGIIENDIALALLDFPV 203
           P     + L   V+L + +++++ +   ++PV  +++H  F +  I   DIAL  L+ PV
Sbjct: 78  PDVKDLAALR--VQLREQHLYYQDQ---LLPVSRIIVHPQFYTAQI-GADIALLELEEPV 131

Query: 204 NYSTHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEKIVTEPQEAELSIILHDKCNEVLK 263
           N S+H+  V LP  +     G  CWVTGWG V+  E++       ++ + + +  N +  
Sbjct: 132 NVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIME--NHICD 189

Query: 264 EKIRMRS------EMVKKGTICGYNDQGKDACQ-ILGGP 295
            K  + +       +V+   +C  N + +D+CQ   GGP
Sbjct: 190 AKYHLGAYTGDDVRIVRDDMLCAGNTR-RDSCQGDSGGP 227


>gi|223942069 enterokinase precursor [Homo sapiens]
          Length = 1019

 Score =  108 bits (271), Expect = 4e-24
 Identities = 70/219 (31%), Positives = 116/219 (52%), Gaps = 27/219 (12%)

Query: 89  ACGQR------TSRITGGLPAPDRKWPWQVSLQTSNRHICGGSLIARHWVLTAAHCISGV 142
           +CG++      T +I GG  A +  WPW V L    R +CG SL++  W+++AAHC+   
Sbjct: 771 SCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVY-- 828

Query: 143 DPGGSSCSHLEYTVKLGDTNVHHRSK--TALVVP--VRDVVIHRYFTSPGIIENDIALAL 198
              G +    ++T  LG   +H +S   +   VP  + ++VI+ ++      +NDIA+  
Sbjct: 829 ---GRNLEPSKWTAILG---LHMKSNLTSPQTVPRLIDEIVINPHYNRRR-KDNDIAMMH 881

Query: 199 LDFPVNYSTHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEKIVTEPQEAELSIILHDKC 258
           L+F VNY+ +IQ +CLPE+  +   G NC + GWG V          QEA++ ++ +++C
Sbjct: 882 LEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERC 941

Query: 259 NEVLKEKIRMRSEMVKKGTIC-GYNDQGKDACQ-ILGGP 295
            +      +M    + +  IC GY + G D+CQ   GGP
Sbjct: 942 QQ------QMPEYNITENMICAGYEEGGIDSCQGDSGGP 974


>gi|148231605 ovochymase 2 [Homo sapiens]
          Length = 564

 Score =  108 bits (271), Expect = 4e-24
 Identities = 70/226 (30%), Positives = 111/226 (49%), Gaps = 24/226 (10%)

Query: 80  RPASVLLPSA--CGQRT------------SRITGGLPAPDRKWPWQVSLQTSNRHICGGS 125
           + A++ LP A  CGQ              SRI GG       +PWQVSL+   +HICGGS
Sbjct: 21  KSATLSLPKAPSCGQSLVKVQPWNYFNIFSRILGGSQVEKGSYPWQVSLKQRQKHICGGS 80

Query: 126 LIARHWVLTAAHCISGVDPGGSSCSHLEYTVKLGDTNVHHRSKTALVVPVRDVVIHRYFT 185
           +++  WV+TAAHCI+      +  S L  T   G+ ++         + +  V+IH +F+
Sbjct: 81  IVSPQWVITAAHCIA----NRNIVSTLNVTA--GEYDLSQTDPGEQTLTIETVIIHPHFS 134

Query: 186 SPGIIENDIALALLDFPVNYSTHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEKIVTEP 245
           +   ++ DIAL  +     +   +  +CLPE     +AG  C   GWG++ E   +    
Sbjct: 135 TKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQFEAGFICTTAGWGRLTEGGVLSQVL 194

Query: 246 QEAELSIILHDKCNEVLKEKIRMRSEMVKKGTIC-GYNDQGKDACQ 290
           QE  L I+  ++C   L   + ++  +  K  +C G+ D G+DACQ
Sbjct: 195 QEVNLPILTWEECVAAL---LTLKRPISGKTFLCTGFPDGGRDACQ 237


>gi|34098976 marapsin 2 [Homo sapiens]
          Length = 326

 Score =  108 bits (270), Expect = 6e-24
 Identities = 73/241 (30%), Positives = 112/241 (46%), Gaps = 25/241 (10%)

Query: 63  VGAPGSPAAPQSRGNAVRPASVLLPSACGQRT--SRITGGLPAPDRKWPWQVSLQTSNRH 120
           V AP   AA   R    +  S+    ACG+ +   +I GG+PAP+RKWPWQVS+  +  H
Sbjct: 24  VVAPPRVAALVHRQPENQGISLTGSVACGRPSMEGKILGGVPAPERKWPWQVSVHYAGLH 83

Query: 121 ICGGSLIARHWVLTAAHCISGVDPGGSSCSHLEYTVKLGD-----TNVHHRSKTALVVPV 175
           +CGGS++  +WVL+AAHC            H +  +K+ D      N+           V
Sbjct: 84  VCGGSILNEYWVLSAAHCF-----------HRDKNIKIYDMYVGLVNLRVAGNHTQWYEV 132

Query: 176 RDVVIHRYFTSPGIIENDIALALLDFPVNYSTHIQLVCLPEQAFMVQAGTNCWVTGWGKV 235
             V++H  +     I  D+AL  L   + +S  +  VCL      +    NCW TGWG V
Sbjct: 133 NRVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLATPEVNL-TSANCWATGWGLV 191

Query: 236 NETEKIVTEPQEAELSIILHDKCNEVLKEKIRMRSEMVKKG------TICGYNDQGKDAC 289
           ++  +   E QE +L +IL   C+ +      +  +M+  G      T+C  +  G   C
Sbjct: 192 SKQGETSDELQEMQLPLILEPWCHLLYGHMSYIMPDMLCAGDILNAKTVCEGDSGGPLVC 251

Query: 290 Q 290
           +
Sbjct: 252 E 252


>gi|148806900 epidermis-specific serine protease-like protein [Homo
           sapiens]
          Length = 328

 Score =  108 bits (269), Expect = 7e-24
 Identities = 77/219 (35%), Positives = 108/219 (49%), Gaps = 19/219 (8%)

Query: 88  SACGQR--TSRITGGLPAPDRKWPWQVSLQTSNRHICGGSLIARHWVLTAAHCISGVDPG 145
           S CGQ   +SR+ GG  A   +WPWQVSL   +  ICGGSL++   +LTAAHCI      
Sbjct: 17  SVCGQPVYSSRVVGGQDAAAGRWPWQVSLHFDHNFICGGSLVSERLILTAAHCIQ----- 71

Query: 146 GSSCSHLEYTVKLGDTNVHHRSKTALVVPVRDVVIHRYFTSPGIIENDIALALLDFPVNY 205
             + +   YTV LG   V   S+  +   V  +VIH  +        D+AL  L   V +
Sbjct: 72  -PTWTTFSYTVWLGSITVGD-SRKRVKYYVSKIVIHPKYQD---TTADVALLKLSSQVTF 126

Query: 206 STHIQLVCLPEQAFMVQAGTNCWVTGWGKVNET--EKIVTEPQEAELSIILHDKCNEVLK 263
           ++ I  +CLP     +     CWVTGWGKV E+      +  QEAE+ II    C ++  
Sbjct: 127 TSAILPICLPSVTKQLAIPPFCWVTGWGKVKESSDRDYHSALQEAEVPIIDRQACEQLYN 186

Query: 264 E---KIRMRSEMVKKGTICGYNDQG-KDACQ-ILGGPWS 297
                +     ++K+  IC  + Q  KD+C+   GGP S
Sbjct: 187 PIGIFLPALEPVIKEDKICAGDTQNMKDSCKGDSGGPLS 225


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.433 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,187,530
Number of Sequences: 37866
Number of extensions: 794724
Number of successful extensions: 8039
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 276
Number of HSP's successfully gapped in prelim test: 282
Number of HSP's that attempted gapping in prelim test: 4937
Number of HSP's gapped (non-prelim): 2660
length of query: 299
length of database: 18,247,518
effective HSP length: 102
effective length of query: 197
effective length of database: 14,385,186
effective search space: 2833881642
effective search space used: 2833881642
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.