Guide to the Human Genome
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Search of human proteins with 239752495

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239752495 PREDICTED: similar to nebulin [Homo sapiens]
         (237 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239752495 PREDICTED: similar to nebulin [Homo sapiens]             493   e-140
gi|169217576 PREDICTED: similar to nebulin [Homo sapiens]             357   7e-99
gi|115527120 nebulin [Homo sapiens]                                   253   8e-68
gi|46049092 nebulin-related anchoring protein isoform C [Homo sa...   159   3e-39
gi|46049105 nebulin-related anchoring protein isoform S [Homo sa...   159   3e-39
gi|5453758 nebulette sarcomeric isoform [Homo sapiens]                 62   3e-10
gi|47087157 nebulette non-muscle isoform [Homo sapiens]                37   0.011
gi|5453710 LIM and SH3 protein 1 [Homo sapiens]                        37   0.019
gi|127138957 zinc finger protein 537 [Homo sapiens]                    30   1.4  
gi|222352158 carboxypeptidase 3, cytosolic [Homo sapiens]              30   2.4  
gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa...    30   2.4  
gi|110349721 titin isoform novex-3 [Homo sapiens]                      29   4.1  
gi|110349719 titin isoform N2-A [Homo sapiens]                         29   4.1  
gi|110349717 titin isoform novex-2 [Homo sapiens]                      29   4.1  
gi|110349713 titin isoform novex-1 [Homo sapiens]                      29   4.1  
gi|110349715 titin isoform N2-B [Homo sapiens]                         29   4.1  
gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens]     28   5.3  
gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens]      28   5.3  
gi|45446749 kinesin family member 5A [Homo sapiens]                    28   5.3  
gi|87298937 centrosomal protein 110kDa [Homo sapiens]                  28   5.3  
gi|19923424 myotubularin related protein 9 [Homo sapiens]              28   9.0  
gi|112380630 leiomodin 1 (smooth muscle) [Homo sapiens]                28   9.0  

>gi|239752495 PREDICTED: similar to nebulin [Homo sapiens]
          Length = 237

 Score =  493 bits (1269), Expect = e-140
 Identities = 237/237 (100%), Positives = 237/237 (100%)

Query: 1   MHLSCLFPKPHTYDLSLPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSD 60
           MHLSCLFPKPHTYDLSLPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSD
Sbjct: 1   MHLSCLFPKPHTYDLSLPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSD 60

Query: 61  REYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKA 120
           REYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKA
Sbjct: 61  REYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKA 120

Query: 121 YDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTP 180
           YDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTP
Sbjct: 121 YDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTP 180

Query: 181 EVIQAKINAVQISEVEKSRDNFNVRHYGSYLDQKQLGPAQQWELSELSAMWTYPSDN 237
           EVIQAKINAVQISEVEKSRDNFNVRHYGSYLDQKQLGPAQQWELSELSAMWTYPSDN
Sbjct: 181 EVIQAKINAVQISEVEKSRDNFNVRHYGSYLDQKQLGPAQQWELSELSAMWTYPSDN 237


>gi|169217576 PREDICTED: similar to nebulin [Homo sapiens]
          Length = 410

 Score =  357 bits (915), Expect = 7e-99
 Identities = 177/188 (94%), Positives = 178/188 (94%), Gaps = 6/188 (3%)

Query: 23  YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
           YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS
Sbjct: 50  YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 109

Query: 83  IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142
           IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL
Sbjct: 110 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 169

Query: 143 PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEV------E 196
           PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE       E
Sbjct: 170 PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWE 229

Query: 197 KSRDNFNV 204
           K + N NV
Sbjct: 230 KEKANVNV 237



 Score =  136 bits (342), Expect = 2e-32
 Identities = 62/104 (59%), Positives = 78/104 (75%)

Query: 23  YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
           Y YK  Y KQ GH++G R+ ++DPK VWA +  K+Q+DR YKKAY   K   + P+DM+S
Sbjct: 293 YLYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVS 352

Query: 83  IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSD 126
           I  AK+ Q L SD+DYR+YLH W+C PDQNDVIQA+KAYDLQSD
Sbjct: 353 ISAAKEGQALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 50/194 (25%), Positives = 89/194 (45%), Gaps = 15/194 (7%)

Query: 39  FRTLQDDPKSVWA-IHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDID 97
           F ++ D P+ + A I+A +I S+  Y+ A+EK K   N P D   ++Q+K   + +S+  
Sbjct: 200 FTSIVDTPEVIQAKINAVQI-SEPLYRNAWEKEKANVNVPADTPLMLQSKINALQISNKR 258

Query: 98  YRN-----YLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG--IGW-LPEGSVEV 149
           Y+       +  +    D   +  AK + D+ SD LYK+  E  KG  IG    +   ++
Sbjct: 259 YQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYIGCRSAKEDPKL 318

Query: 150 MRVKNAQNLLNERLYR--IKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNFNVRHY 207
           +   N   + N+RLY+        K +  VD   +  AK      S+V+       + H+
Sbjct: 319 VWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDVDY---RHYLHHW 375

Query: 208 GSYLDQKQLGPAQQ 221
             + DQ  +  A++
Sbjct: 376 SCFPDQNDVIQARK 389


>gi|115527120 nebulin [Homo sapiens]
          Length = 6669

 Score =  253 bits (647), Expect = 8e-68
 Identities = 121/198 (61%), Positives = 151/198 (76%), Gaps = 12/198 (6%)

Query: 9    KPHTYDLSLPEVP------------SYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAK 56
            K   YDL L  +P             YKYKEGYRKQLGHH+G R ++DDPK +W+IH AK
Sbjct: 3495 KKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHIGARNIKDDPKMMWSIHVAK 3554

Query: 57   IQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQ 116
            IQSDREYKK +EK K   ++P+DM+ +V AKKCQ+LVSDIDY++ LH+WTCLPDQNDVIQ
Sbjct: 3555 IQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVSDIDYKHPLHEWTCLPDQNDVIQ 3614

Query: 117  AKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSI 176
            A+KAYDLQSD +YKSDLEWL+GIGW+P GSVEV +VK A  +L++R YR   + LKFT I
Sbjct: 3615 ARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAGEILSDRKYRQPADQLKFTCI 3674

Query: 177  VDTPEVIQAKINAVQISE 194
             DTPE++ AK NA+ +S+
Sbjct: 3675 TDTPEIVLAKNNALTMSK 3692



 Score =  249 bits (635), Expect = 2e-66
 Identities = 115/171 (67%), Positives = 143/171 (83%)

Query: 23   YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
            YKYKE Y KQ GHH+G ++++DDPK + AIHA KIQS+REYKK ++K K   ++P+DM+S
Sbjct: 3764 YKYKEAYEKQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLS 3823

Query: 83   IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142
            I+ AKKCQ LV+DIDYRNYLH+WTC+PDQND+IQAKKAYDLQSD LYK+DLEWL+GIGW+
Sbjct: 3824 ILLAKKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWM 3883

Query: 143  PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQIS 193
            P+GS EV+RVKNAQN+  + +YR     LK+TSIVDTPEV+ AK NA  IS
Sbjct: 3884 PQGSPEVLRVKNAQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENIS 3934



 Score =  248 bits (632), Expect = 4e-66
 Identities = 116/198 (58%), Positives = 148/198 (74%), Gaps = 12/198 (6%)

Query: 9    KPHTYDLSLPEVP------------SYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAK 56
            K   YDL    +P             YKYKE YRKQLGHH+G R + DDPK +W++H AK
Sbjct: 3252 KKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDDPKIMWSLHIAK 3311

Query: 57   IQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQ 116
            +QSDREYKK +EK K  +++P+DM+ IV AKKCQ LVSD+DY++ LH+W CLPDQND+I 
Sbjct: 3312 VQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHPLHEWICLPDQNDIIH 3371

Query: 117  AKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSI 176
            A+KAYDLQSDNLYKSDLEW+KGIGW+P  S+EV+R K A  LL++ +YR +PE LKFTSI
Sbjct: 3372 ARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDTIYRQRPETLKFTSI 3431

Query: 177  VDTPEVIQAKINAVQISE 194
             DTPE + AK NA+ +++
Sbjct: 3432 TDTPEQVLAKNNALNMNK 3449



 Score =  245 bits (626), Expect = 2e-65
 Identities = 106/175 (60%), Positives = 145/175 (82%)

Query: 20   VPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLD 79
            +  YKYK+GYRKQLGHH+G R ++DDPK +W++H AKIQSDREYKK +EK K   ++P+D
Sbjct: 3032 ISDYKYKDGYRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVD 3091

Query: 80   MMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGI 139
            M+ +V AKKCQ LVSD+DY+NYLH+WTCLPDQNDVI A++AYDLQSDN+YKSDL+WL+GI
Sbjct: 3092 MLGVVLAKKCQTLVSDVDYKNYLHEWTCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGI 3151

Query: 140  GWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE 194
            GW+P GS++V++ K A  +L++ +YR  P+ LKFTS+ D+ E + AK NA+ +++
Sbjct: 3152 GWVPIGSMDVVKCKRAAEILSDNIYRQPPDKLKFTSVTDSLEQVLAKNNALNMNK 3206



 Score =  237 bits (605), Expect = 6e-63
 Identities = 103/172 (59%), Positives = 142/172 (82%)

Query: 23   YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
            +KYKEGYRKQLGHH+G R ++DDPK +W++H AKIQSDREYKK +EK K   ++P+DM+ 
Sbjct: 2792 FKYKEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLG 2851

Query: 83   IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142
            +V AKKCQ LVSD+DY+NYLHQWTCLPDQ+DVI A++AYDLQSDN+YKSDL+W++GIGW+
Sbjct: 2852 VVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSDNMYKSDLQWMRGIGWV 2911

Query: 143  PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE 194
              GS++V + K A  +L++++YR  P+  KFTS+ D+ E + AK NA+ +++
Sbjct: 2912 SIGSLDVEKCKRATEILSDKIYRQPPDRFKFTSVTDSLEQVLAKNNALNMNK 2963



 Score =  236 bits (603), Expect = 1e-62
 Identities = 108/193 (55%), Positives = 146/193 (75%), Gaps = 12/193 (6%)

Query: 13   YDLSLPEVP------------SYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSD 60
            YDL +  +P             YKYKEG+RKQLGHH+G R ++DDPK +W++H AKIQSD
Sbjct: 2527 YDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAKIQSD 2586

Query: 61   REYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKA 120
            REYKK +EK K   ++P+DM+ +V AKKCQ LVSD+DY+NYLHQWTCLPDQ+DVI A++A
Sbjct: 2587 REYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQA 2646

Query: 121  YDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTP 180
            YDLQSDNLYKSDL+WLKGIGW+  GS+E  + K A  +L++ +YR  P+  KF+S++D+ 
Sbjct: 2647 YDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFSSLMDSI 2706

Query: 181  EVIQAKINAVQIS 193
             ++ AK NA+ ++
Sbjct: 2707 PMVLAKNNAITMN 2719



 Score =  236 bits (602), Expect = 1e-62
 Identities = 108/172 (62%), Positives = 139/172 (80%)

Query: 23   YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
            YKYK+GYRKQLGHH+GFR+LQDDPK V +++ AK+QS+REYKK +EK K   ++P+DM+ 
Sbjct: 2306 YKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTKFSSPVDMLG 2365

Query: 83   IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142
            +V AKKCQ LVSD+DY+NYLHQWTCLPDQNDV+QAKK Y+LQS+NLYKSDLEWL+GIGW 
Sbjct: 2366 VVLAKKCQELVSDVDYKNYLHQWTCLPDQNDVVQAKKVYELQSENLYKSDLEWLRGIGWS 2425

Query: 143  PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE 194
            P GS+E  + K A  +++E+ YR  P+  KFTSI D  +++ AK NA   S+
Sbjct: 2426 PLGSLEAEKNKRASEIISEKKYRQPPDRNKFTSIPDAMDIVLAKTNAKNRSD 2477



 Score =  204 bits (518), Expect = 7e-53
 Identities = 102/184 (55%), Positives = 136/184 (73%), Gaps = 7/184 (3%)

Query: 24   KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
            KYK  + KQ GH++G  T++DDPK VW  HA +IQ++R YK+ Y K+K   N P DM+S+
Sbjct: 4249 KYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKINIPADMVSV 4308

Query: 84   VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143
            + AK+ Q LVSDIDYRNYLHQW C PDQNDVIQA+KAYDLQSDN+Y++DLEWL+GIGW+P
Sbjct: 4309 LAAKQGQTLVSDIDYRNYLHQWMCHPDQNDVIQARKAYDLQSDNVYRADLEWLRGIGWIP 4368

Query: 144  EGSVEVMRVKNAQNLLNERLYRIKPEALK----FTSIVDTPEVIQAKINAVQISEVEKSR 199
              SV+ +RV   Q ++++  Y  K  AL+    F S+VD PE++ AKIN+V  S+V K +
Sbjct: 4369 LDSVDHVRVTKNQEMMSQIKY--KKNALENYPNFRSVVDPPEIVLAKINSVNQSDV-KYK 4425

Query: 200  DNFN 203
            + FN
Sbjct: 4426 ETFN 4429



 Score =  198 bits (504), Expect = 3e-51
 Identities = 92/178 (51%), Positives = 128/178 (71%)

Query: 23   YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
            YKYK  + KQ GH++G  T +DD K  WA+ A K+Q++REY+  + K K    +P+DM+S
Sbjct: 4006 YKYKLDHEKQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLS 4065

Query: 83   IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142
            I+ +K  Q LVSD+DYRNYLHQWTC+PDQNDVIQAKKAY+LQSDN+YK+DLEWL+GIGW+
Sbjct: 4066 ILHSKNSQALVSDMDYRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWM 4125

Query: 143  PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRD 200
            P  SV V   K+A ++ +E+ YR K E L FT + D  + + AK +   + +++  +D
Sbjct: 4126 PNDSVSVNHAKHAADIFSEKKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKD 4183



 Score =  189 bits (481), Expect = 1e-48
 Identities = 93/184 (50%), Positives = 131/184 (71%), Gaps = 1/184 (0%)

Query: 24   KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
            +YK+ Y K  G  +GF++LQDDPK V  ++ AKIQSDREYKK YEK+K  +NTP DM ++
Sbjct: 1087 QYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNV 1146

Query: 84   VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGWL 142
            V AKK Q +VS+++Y++ LH +T LPD  D+  +K    +QSDN+YK D   W+KGIGW+
Sbjct: 1147 VAAKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWI 1206

Query: 143  PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNF 202
            P GS++V +VK A + LNE+ YR  P+ LKFTSIVD+P ++QAK N  Q+S++       
Sbjct: 1207 PIGSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGE 1266

Query: 203  NVRH 206
            +V+H
Sbjct: 1267 DVKH 1270



 Score =  176 bits (446), Expect = 2e-44
 Identities = 86/172 (50%), Positives = 118/172 (68%), Gaps = 1/172 (0%)

Query: 25   YKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIV 84
            YK+ Y K  G  +G  ++ DDPK + ++  AK QSDREY+K YEKSK I+  PLDM+ + 
Sbjct: 844  YKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVT 903

Query: 85   QAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGWLP 143
            QAKK Q + SD+DY++ LH ++  PD  +V  AKKAY LQSD  YK+D   W+KG GW+P
Sbjct: 904  QAKKSQAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCGWVP 963

Query: 144  EGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEV 195
             GS+E+ + K A ++LNE+ YR  P+ LKFTSI D P  +Q+KIN  Q S++
Sbjct: 964  FGSLEMEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDI 1015



 Score =  172 bits (437), Expect = 2e-43
 Identities = 85/185 (45%), Positives = 124/185 (67%), Gaps = 1/185 (0%)

Query: 23   YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
            YKYKE Y K  G H+GFR+LQDDPK V  ++ AK+QSDREYKK YE +K  ++TP DM+S
Sbjct: 1330 YKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMVS 1389

Query: 83   IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGW 141
            I  AK  Q + ++++Y+  LH +T LPD   +   +    +QSDN+YK +   +LKGIGW
Sbjct: 1390 ITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFLKGIGW 1449

Query: 142  LPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDN 201
            +P GS+EV +VK A + LNER YR  P+ +KFTS+ D+  ++ A+ N  Q+S++    + 
Sbjct: 1450 IPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLNYKVEG 1509

Query: 202  FNVRH 206
              ++H
Sbjct: 1510 EKLKH 1514



 Score =  167 bits (424), Expect = 6e-42
 Identities = 86/172 (50%), Positives = 114/172 (66%), Gaps = 1/172 (0%)

Query: 24   KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
            KYKE Y K  G  +GF +LQDDPK V  ++ AKIQSDREYKK YE SK  ++TPLDM+S+
Sbjct: 1575 KYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTPLDMVSV 1634

Query: 84   VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGWL 142
              AKK Q + ++ +YR   H +T LPD  +V  ++ A  +QSDNLYKSD   W+KGIGW+
Sbjct: 1635 TAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDFTNWMKGIGWV 1694

Query: 143  PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE 194
            P  S+EV + K A  +L+E+ YR  PE LKFT  +DT E    K N + + +
Sbjct: 1695 PIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSNKLNMDK 1746



 Score =  166 bits (421), Expect = 1e-41
 Identities = 80/173 (46%), Positives = 120/173 (69%), Gaps = 1/173 (0%)

Query: 23   YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
            YKYK+ Y +  G H+GFR+L+DDPK V  +  AK+QSDREYKK YEKSK   +TP+DM+S
Sbjct: 1818 YKYKKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLS 1877

Query: 83   IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSD-LEWLKGIGW 141
            +V AKK Q + ++ +YRN +H +  LPD      AK    +QSDN YK+D  +++KGIGW
Sbjct: 1878 VVAAKKSQEVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQSDNQYKADYADFMKGIGW 1937

Query: 142  LPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE 194
            LP GS+E  + K A  +++E+ YR  P+ LK+++++D+  ++ A+ NA  ++E
Sbjct: 1938 LPLGSLEAEKNKKAMEIISEKKYRQHPDTLKYSTLMDSMNMVLAQNNAKIMNE 1990



 Score =  148 bits (374), Expect = 4e-36
 Identities = 71/168 (42%), Positives = 107/168 (63%), Gaps = 1/168 (0%)

Query: 23   YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
            YKYK  Y K  G  +GFR+L+DDPK V ++  AK+QSDREYKK YE +K  ++TP DM+S
Sbjct: 2062 YKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENTKTSYHTPADMLS 2121

Query: 83   IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGW 141
            +  AK  Q  +++ +Y++ +H++  LPD  ++   +    +QSDN YK D  EW KG+GW
Sbjct: 2122 VTAAKDAQANITNTNYKHLIHKYILLPDAMNIELTRNMNRIQSDNEYKQDYNEWYKGLGW 2181

Query: 142  LPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINA 189
             P GS+EV + K A    +++ YR  P   +F  + D+ +++ AK NA
Sbjct: 2182 SPAGSLEVEKAKKATEYASDQKYRQHPSNFQFKKLTDSMDMVLAKQNA 2229



 Score =  129 bits (325), Expect = 2e-30
 Identities = 66/182 (36%), Positives = 109/182 (59%), Gaps = 3/182 (1%)

Query: 24   KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
            KYKE Y KQ GH++  + + + P  V  +   K++S   Y+K YE +K   + P DMM+ 
Sbjct: 4494 KYKETYEKQKGHYLAGKVIGEFPGVVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNH 4553

Query: 84   VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143
            V AK+CQ ++SD++YR+Y HQWT L ++ +VI+ + A ++ SDN+YK DL WLKGIG   
Sbjct: 4554 VLAKRCQYILSDLEYRHYFHQWTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCYV 4613

Query: 144  EGSVEVMRVKNAQNLLNERLYRI--KPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDN 201
              + +++  K + +L ++  Y    K     +  + DTP  + A  + +  SEV K ++N
Sbjct: 4614 WDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINASEV-KYKEN 4672

Query: 202  FN 203
            ++
Sbjct: 4673 YH 4674



 Score =  107 bits (268), Expect = 7e-24
 Identities = 67/176 (38%), Positives = 95/176 (53%), Gaps = 8/176 (4%)

Query: 24   KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSK-GIHNTPLDMMS 82
            KY+E Y K    +   R++ DDP +   +   K+  DR Y+  YEK+K  IH  P DM+ 
Sbjct: 4739 KYREEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVP-DMVE 4797

Query: 83   IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142
            +V AK  Q  VS+IDYR  LH+W C PD       +K  D  SD +YK DL WLKGIG  
Sbjct: 4798 MVTAKDSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCY 4857

Query: 143  PEGSVEVMRVKNAQNLLNERLYRIKPEALK----FTSIVDTPEVIQAKINAVQISE 194
               + E++  K+A +L ++  Y  K   LK    +  + DTP  +QA  +  Q+S+
Sbjct: 4858 VWDTPEILHAKHAYDLRDDIKY--KAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSD 4911



 Score = 81.6 bits (200), Expect = 5e-16
 Identities = 50/188 (26%), Positives = 88/188 (46%), Gaps = 9/188 (4%)

Query: 25  YKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSK----GIHNTPLDM 80
           YK+ Y K  G  +G  ++ DDPK + ++  AK QSDR YK+ YEK+K        TP   
Sbjct: 597 YKKDYEKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQ 656

Query: 81  MSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIG 140
           +        +    D+  ++ L  +    +        K     SD  YK++ E  KG  
Sbjct: 657 LDTQLKNFSEARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKC 716

Query: 141 WLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRD 200
           + P+   +        +   +  Y++ P+  KFT++ D+P ++QA++N  Q+S++     
Sbjct: 717 YFPQTITQEYEAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDL----- 771

Query: 201 NFNVRHYG 208
           N+  +H G
Sbjct: 772 NYKAKHEG 779



 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 58/185 (31%), Positives = 91/185 (49%), Gaps = 20/185 (10%)

Query: 23   YKYKEGYR--KQLGHHMGFRTLQDDPKSVWAIHAAKIQ---SDREYKKAYEKSKG-IHNT 76
            +KYKE Y   K  G+ +G       PK V  +H  ++    S+R Y++ Y K K  IH T
Sbjct: 4983 FKYKEAYEHTKAYGYTLG-------PKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTT 5035

Query: 77   PLDMMSIVQAKKCQVLVSDIDYRNYLHQWT----CLPDQNDVIQAKKAYDLQSDNLYKSD 132
            P D   I Q KK Q  VS++ Y++   +       LP    VI  +   D+ SD  YK D
Sbjct: 5036 P-DTPEIRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKED 5094

Query: 133  LEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEAL--KFTSIVDTPEVIQAKINAV 190
            L+ LKG G     + +++R ++ + L +  LY  K   +  K+  ++DTPE  + +    
Sbjct: 5095 LQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKT 5154

Query: 191  QISEV 195
             +SE+
Sbjct: 5155 HLSEL 5159



 Score = 72.4 bits (176), Expect = 3e-13
 Identities = 66/231 (28%), Positives = 96/231 (41%), Gaps = 52/231 (22%)

Query: 20   VPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLD 79
            V   KYK  Y K       +  + D P  + A  A    SD  YK+ ++K+KG ++T  D
Sbjct: 5226 VSEKKYKIQYEKMKDK---YTPVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKD 5282

Query: 80   MMSIVQAKKCQVLVSDIDYR-NYLHQ---WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEW 135
             + IV  +K    +S I Y+ NY+ Q   W  +PD+ +    +   D  SD  YK DL W
Sbjct: 5283 ALDIVYHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTW 5342

Query: 136  LKGIG------------------------------------WLPEGSVEVMRVKNAQNLL 159
            LKGIG                                    ++ +  +     K A  L+
Sbjct: 5343 LKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPIN-RHFKYATQLM 5401

Query: 160  NERLYRIKPEAL--KFTSIVDTPEVIQAKINAVQISEV------EKSRDNF 202
            NE+ YR   E    K+  +VD P  + AK    QIS++      EKS+D F
Sbjct: 5402 NEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKF 5452



 Score = 69.7 bits (169), Expect = 2e-12
 Identities = 61/245 (24%), Positives = 111/245 (45%), Gaps = 54/245 (22%)

Query: 22   SYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMM 81
            SY+YK+ Y K  GH   + T+ D+ + +    A ++QS  +YK+ YEK +G      +  
Sbjct: 5864 SYQYKKKYEKSKGH---YHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETP 5920

Query: 82   SIVQAKKCQVLVSDIDYRN-------------------YLH------------------- 103
            + + AK+ Q + S  +YR                     LH                   
Sbjct: 5921 TYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLEE 5980

Query: 104  -----QWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWL---KGIGWLPEGSVEVMRVKNA 155
                   T + D  D+++AK A  + ++  YK DLE     +G+  +   + + MR +NA
Sbjct: 5981 SIRGKGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNA 6040

Query: 156  QNLLNERLYRIKPEALK--FTSIVDTPEVIQAKINAVQISEVEKSRDNF--NVRHYGSYL 211
             ++ ++  Y+   E  K  FTS+VDTPE+I A+     +S  +K +++   ++ +Y + L
Sbjct: 6041 TDIASQIKYKQSAEMEKANFTSVVDTPEIIHAQ-QVKNLSSQKKYKEDAEKSMSYYETVL 6099

Query: 212  DQKQL 216
            D  ++
Sbjct: 6100 DTPEI 6104



 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 54/191 (28%), Positives = 88/191 (46%), Gaps = 26/191 (13%)

Query: 19   EVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQ---SDREYKKAYEKSKGIHN 75
            ++    YK  Y K      G+ T+ D P     +H  K++   SD +YK+ Y+++K    
Sbjct: 5470 QISDILYKLEYNK--AKPRGYTTIHDTPM---LLHVRKVKDEVSDLKYKEVYQRNKSNCT 5524

Query: 76   TPLDMMSIVQAKKCQVLVSDIDYRNYLH----QWTCLPDQNDVIQAKKAYDLQSDNLYKS 131
               D + I  AK    + +++DY+         W   PD+ D +QA K+   QSD  YK 
Sbjct: 5525 IEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEYKL 5584

Query: 132  DLEWLKGIGWLPEGSVEVMRVKNA----QNLLNERLYRIKPEALK----FTSIVDTPEVI 183
            D E+LKG        + V   KN     +N L E   + K + +K      ++ DTP+++
Sbjct: 5585 DREFLKGC------KLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQIL 5638

Query: 184  QAKINAVQISE 194
             AK  +  +SE
Sbjct: 5639 LAKTVSNLVSE 5649



 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 48/167 (28%), Positives = 78/167 (46%), Gaps = 13/167 (7%)

Query: 41   TLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRN 100
            ++ DD  +V A+    I+SD +YK+ + K +G  +   D   I+ AK    LVS+  Y++
Sbjct: 5595 SVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTVSNLVSENKYKD 5654

Query: 101  YLHQ------WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG-----IGWLPEGSVEV 149
            ++ +      +T LP+  D +  K+     SD  YK      KG     I   P      
Sbjct: 5655 HVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEPPEVKHA 5714

Query: 150  MRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVE 196
            M V   Q+ +  R  +   E L +T++ D P++ +A   A Q SEVE
Sbjct: 5715 MEVAKKQSDVAYR--KDAKENLHYTTVADRPDIKKATQAAKQASEVE 5759



 Score = 57.8 bits (138), Expect = 8e-09
 Identities = 45/189 (23%), Positives = 82/189 (43%), Gaps = 11/189 (5%)

Query: 24  KYKEGYRKQLGH-HMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIH----NTP- 77
           KYKE Y K  G          ++P+      A    SD+ YK+ YEK+K        TP 
Sbjct: 347 KYKEDYEKNKGKADYNVLPASENPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPK 406

Query: 78  LDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLK 137
             + +++Q         D   ++ L  +    +        K     SD  YK++ E  +
Sbjct: 407 FKLDTVLQNFSSDKKYKDSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDR 466

Query: 138 GIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEK 197
           G G+ P+   +        +   +  Y++ P+  KFT + D+P ++QA++N+ Q+S++  
Sbjct: 467 GKGFFPQTITQEYEAIKKLDQCKDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDL-- 524

Query: 198 SRDNFNVRH 206
              N+  +H
Sbjct: 525 ---NYKAKH 530



 Score = 57.8 bits (138), Expect = 8e-09
 Identities = 51/177 (28%), Positives = 84/177 (47%), Gaps = 15/177 (8%)

Query: 24   KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
            KYK+    +  +   F ++ D P+ + A     + S ++YK+  EKS   + T LD   I
Sbjct: 6048 KYKQSAEMEKAN---FTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSYYETVLDTPEI 6104

Query: 84   VQAKKCQ----VLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGI 139
             + ++ Q    +L    D +N   + T + D  ++++ K+     S  LYK D+     I
Sbjct: 6105 QRVRENQKNFSLLQYQCDLKNSKGKITVVQDTPEILRVKENQKNFSSVLYKEDVSPGTAI 6164

Query: 140  GWLPEGSVEVMRVKNAQNLLNERLYRIKPEAL-KFTSIVDTPEVIQAKINAVQISEV 195
            G  P    E+MRVK  Q+ ++   Y+   EA+ + T I D PEV + K     IS V
Sbjct: 6165 GKTP----EMMRVKQTQDHISSVKYK---EAIGQGTPIPDLPEVKRVKETQKHISSV 6214



 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 51/183 (27%), Positives = 78/183 (42%), Gaps = 9/183 (4%)

Query: 19   EVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPL 78
            ++   KYKE Y  QLG    +R++ D P+           SD +YK+     KGI     
Sbjct: 5295 DISKIKYKENYMSQLGI---WRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIGCYAY 5351

Query: 79   DMMSIVQAKKCQVLVSDIDYRNYLHQ----WTCLPDQNDVIQAKKAYDLQSDNLYKSDLE 134
            D      A+K + L S   Y+    +    +  + D       K A  L ++  Y++D E
Sbjct: 5352 DTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPINRHFKYATQLMNEKKYRADYE 5411

Query: 135  WLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEAL--KFTSIVDTPEVIQAKINAVQI 192
              K    L       +  K A + +++  YR   E    KFTSIVDTPE ++      QI
Sbjct: 5412 QRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPEHLRTTKVNKQI 5471

Query: 193  SEV 195
            S++
Sbjct: 5472 SDI 5474



 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 42/165 (25%), Positives = 79/165 (47%), Gaps = 7/165 (4%)

Query: 29   YRKQLGHHMGFRT-LQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAK 87
            Y++ L    GF   L D P  V + H  K+ S+  Y     K +  +   LD     + +
Sbjct: 5091 YKEDLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQ 5150

Query: 88   KCQVLVSDIDYR----NYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143
            + +  +S++ YR         +T +PD  D+++AK+   LQS  LY       +      
Sbjct: 5151 ELKTHLSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAG 5210

Query: 144  EGSVEVMRVKNAQNLLNERLYRIKPEAL--KFTSIVDTPEVIQAK 186
              +  +   K+ +++++E+ Y+I+ E +  K+T + DTP +I+AK
Sbjct: 5211 NQTTALKHAKDVKDMVSEKKYKIQYEKMKDKYTPVPDTPILIRAK 5255



 Score = 51.2 bits (121), Expect = 8e-07
 Identities = 55/208 (26%), Positives = 95/208 (45%), Gaps = 15/208 (7%)

Query: 25   YKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIV 84
            YK+ Y     H   ++   D P  + A  ++  QSD EYK   E  KG   +  D  + V
Sbjct: 5547 YKKQYEANKAH---WKWTPDRPDFLQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTV 5603

Query: 85   QAKKCQVLVSDIDYR--NYLHQWTC--LPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIG 140
             A +  ++ SD+ Y+  +   + TC  +PD   ++ AK   +L S+N YK  ++     G
Sbjct: 5604 LALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTVSNLVSENKYKDHVKKHLAQG 5663

Query: 141  ---WLPEGSVEVMRVKNAQNLLNERLYRIKPEALK----FTSIVDTPEVIQAKINAVQIS 193
                LPE + + + VK     +++  Y+ K    K    ++ +++ PEV  A   A + S
Sbjct: 5664 SYTTLPE-TRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEPPEVKHAMEVAKKQS 5722

Query: 194  EVEKSRDNFNVRHYGSYLDQKQLGPAQQ 221
            +V   +D     HY +  D+  +  A Q
Sbjct: 5723 DVAYRKDAKENLHYTTVADRPDIKKATQ 5750



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 50/187 (26%), Positives = 82/187 (43%), Gaps = 10/187 (5%)

Query: 24  KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQ-SDREYKKAYEKSKGIHNTPLDMMS 82
           KYKE + K  G      T   D   +  I   + Q S+ +Y+   + +K I +       
Sbjct: 100 KYKEKFEKTKGQPYASTT---DTPELRRIKKVQDQLSEVKYRMDGDVAKTICHVDEKAKD 156

Query: 83  IVQAKKCQVLVSDIDYRNYLH----QWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG 138
           I  AKK    VS + Y+        ++   PD  +++QA K   + S  LY  D E  K 
Sbjct: 157 IEHAKKVSQQVSKVLYKQNWEDTKDKYLLPPDAPELVQAVKNTAMFSKKLYTEDWEADKS 216

Query: 139 IGWLPEGSVEVMRVKNAQNLLNERLYR--IKPEALKFTSIVDTPEVIQAKINAVQISEVE 196
           + +    S E+ RV  AQ  L++  Y+  +  +  +FT + D P++  AK    Q+S+ +
Sbjct: 217 LFYPYNDSPELRRVAQAQKALSDVAYKKGLAEQQAQFTPLADPPDIEFAKKVTNQVSKQK 276

Query: 197 KSRDNFN 203
              D  N
Sbjct: 277 YKEDYEN 283



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 56/205 (27%), Positives = 82/205 (40%), Gaps = 43/205 (20%)

Query: 44   DDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYR-NYL 102
            D P+ + A HA  ++ D +YK    K++  +    D    VQA K    +SD  Y  +Y+
Sbjct: 4860 DTPEILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYV 4919

Query: 103  H--QWTCLPDQN--DVIQAKKAYDLQSDNLYKSDLEWL---------------------- 136
            H  +    P     D+ +A  AY LQS NLYK+ L  L                      
Sbjct: 4920 HSVRGKVAPTTKTVDLDRALHAYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKDTRYM 4979

Query: 137  -------------KGIGW-LPEGSVEVMRVKNAQNLLNERLYRIKPEALK--FTSIVDTP 180
                         K  G+ L    V  + V+   N+ +ERLYR     LK    +  DTP
Sbjct: 4980 SSYFKYKEAYEHTKAYGYTLGPKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTP 5039

Query: 181  EVIQAKINAVQISEVEKSRDNFNVR 205
            E+ Q K     +SE+    D F ++
Sbjct: 5040 EIRQVKKTQEAVSELIYKSDFFKMQ 5064



 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 48/175 (27%), Positives = 89/175 (50%), Gaps = 24/175 (13%)

Query: 51   AIHAAKIQSDREYKKAYEKSK--GIHNTPLDMMSIVQAKKCQVLVSDIDYR----NYLHQ 104
            A  A+ I ++++Y++  +  K   I + P+     VQ+K  Q   SDI Y+      +H+
Sbjct: 972  AKRASDILNEKKYRQHPDTLKFTSIEDAPIT----VQSKINQAQRSDIAYKAKGEEIIHK 1027

Query: 105  WTCLPDQNDVIQAK-KAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNER 162
            +   PD    IQAK  AY++ S+N+YK+DL+ L   G+ L   ++ +   K A+   ++ 
Sbjct: 1028 YNLPPDLPQFIQAKVNAYNI-SENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDV 1086

Query: 163  LY-----RIKPEALKFTSIVDTPEVIQ----AKINAVQ--ISEVEKSRDNFNVRH 206
             Y     + K + + F S+ D P+++     AKI + +    + EK++  +N  H
Sbjct: 1087 QYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPH 1141



 Score = 47.8 bits (112), Expect = 8e-06
 Identities = 45/184 (24%), Positives = 83/184 (45%), Gaps = 10/184 (5%)

Query: 24   KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
            KY+  Y ++      +  + D+P+ + A  A    S  +Y+K YEKSK    + +D    
Sbjct: 5405 KYRADYEQRKDK---YHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPEH 5461

Query: 84   VQAKKCQVLVSDIDYRNYLHQ-----WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG 138
            ++  K    +SDI Y+   ++     +T + D   ++  +K  D  SD  YK   +  K 
Sbjct: 5462 LRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKS 5521

Query: 139  IGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALK--FTSIVDTPEVIQAKINAVQISEVE 196
               +   +V +   K+A  +     Y+ + EA K  +    D P+ +QA  +++Q S+ E
Sbjct: 5522 NCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFE 5581

Query: 197  KSRD 200
               D
Sbjct: 5582 YKLD 5585



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 50/191 (26%), Positives = 77/191 (40%), Gaps = 48/191 (25%)

Query: 56   KIQSDREYKKAY-EKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRN-------------- 100
            +IQSD EYK+ Y E  KG+  +P   + + +AKK     SD  YR               
Sbjct: 2161 RIQSDNEYKQDYNEWYKGLGWSPAGSLEVEKAKKATEYASDQKYRQHPSNFQFKKLTDSM 2220

Query: 101  ----------------YLHQWT-------CLPDQNDVIQAKKAYDLQSDNLYKSDLEWLK 137
                            Y   W         +PD  D++QAK+   L S  LYK   E   
Sbjct: 2221 DMVLAKQNAHTMNKHLYTIDWNKDKTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEAL 2280

Query: 138  GIGW-LPEGSVEVMRVKNAQNLLNERLYRIKPEALK-------FTSIVDTPEVIQAKINA 189
              G+ LP  ++ V   K ++++ ++  Y+ K    K       F S+ D P+++ +   A
Sbjct: 2281 KKGYDLPVDAISVQLAKASRDIASD--YKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVA 2338

Query: 190  VQISEVEKSRD 200
               SE E  +D
Sbjct: 2339 KMQSEREYKKD 2349



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 38/159 (23%), Positives = 72/159 (45%), Gaps = 7/159 (4%)

Query: 44   DDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLH 103
            D P+ + A  +  +QS  +Y  A +++   +N   D    V A +  +  S++ Y+   H
Sbjct: 4615 DTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYH 4674

Query: 104  Q----WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNL 158
            Q    +T + +  D  + +   +L S NLYK   + +K   + LP  ++ +   KN ++L
Sbjct: 4675 QIKDKYTTVLETVDYDRTRNLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHL 4734

Query: 159  LNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEK 197
             +   YR + E  KF ++   P  +    N  +   V K
Sbjct: 4735 ASHIKYREEYE--KFKALYTLPRSVDDDPNTARCLRVGK 4771



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 53/202 (26%), Positives = 83/202 (41%), Gaps = 9/202 (4%)

Query: 19   EVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPL 78
            EV   +    YRK    ++ + T+ D P    A  AAK  S+ EY+  + K      + L
Sbjct: 5716 EVAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEYRAKHRKEGSHGLSML 5775

Query: 79   DMMSIVQAKKCQVLVSDIDYR-NYLHQWTCLPDQNDVIQ-----AKKAYDLQSDNLYKSD 132
                I  AKK   L S + YR N+  +    P  N          K A +L S+  YK+D
Sbjct: 5776 GRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNLASEVKYKAD 5835

Query: 133  LEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALK--FTSIVDTPEVIQAKINAV 190
            L+ L       + S+ +  V N   L +   Y+ K E  K  + +I D  E +  K  A 
Sbjct: 5836 LKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGHYHTIPDNLEQLHLK-EAT 5894

Query: 191  QISEVEKSRDNFNVRHYGSYLD 212
            ++  + K ++ +        LD
Sbjct: 5895 ELQSIVKYKEKYEKERGKPMLD 5916



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 39/145 (26%), Positives = 65/145 (44%), Gaps = 8/145 (5%)

Query: 29   YRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGI-HNTPLDMMSIVQAK 87
            YRK         TL + P    A  AA+I     YK+ +E+ K   +  P D +  V A 
Sbjct: 4180 YRKDWNATKSKYTLTETPLLHTAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAH 4239

Query: 88   KCQVLVSDIDYR-NYLHQ---WTCLPDQND---VIQAKKAYDLQSDNLYKSDLEWLKGIG 140
             C  + S++ Y+  ++ Q   +  +P   D   ++  + A  +Q++ LYK D    K   
Sbjct: 4240 HCNDVQSELKYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKI 4299

Query: 141  WLPEGSVEVMRVKNAQNLLNERLYR 165
             +P   V V+  K  Q L+++  YR
Sbjct: 4300 NIPADMVSVLAAKQGQTLVSDIDYR 4324



 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 42/158 (26%), Positives = 70/158 (44%), Gaps = 10/158 (6%)

Query: 39   FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY 98
            F ++ D    V A H  K  SD  YK   EK K  +    ++   +QAK   + +SD  Y
Sbjct: 1481 FTSVPDSMGMVLAQHNTKQLSDLNYKVEGEKLKHKYTIDPELPQFIQAKVNALNMSDAHY 1540

Query: 99   -----RNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG--IGWLP-EGSVEVM 150
                 +     +   PD   ++ AK + ++ SD  YK   E  KG  +G+L  +   +++
Sbjct: 1541 KADWKKTIAKGYDLRPDAIPIVAAKSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLV 1600

Query: 151  RVKNAQNLLNERLYRIKPEA--LKFTSIVDTPEVIQAK 186
               N   + ++R Y+   EA   K+ + +D   V  AK
Sbjct: 1601 HYMNVAKIQSDREYKKGYEASKTKYHTPLDMVSVTAAK 1638



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 35/106 (33%), Positives = 53/106 (50%), Gaps = 7/106 (6%)

Query: 39   FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSK-GIHNTPLDMMSIVQAKKCQVLVSDID 97
            + TL D    V A + AKI ++  YK+A+E  K  +H  P D+  I+ AK   + +SD  
Sbjct: 1969 YSTLMDSMNMVLAQNNAKIMNEHLYKQAWEADKTKVHIMP-DIPQIILAKANAINMSDKL 2027

Query: 98   YRNYLHQ-----WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG 138
            Y+  L +     +   PD   +  AK + D+ SD  YK + E  KG
Sbjct: 2028 YKLSLEESKKKGYDLRPDAIPIKAAKASRDIASDYKYKYNYEKGKG 2073



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 41/155 (26%), Positives = 63/155 (40%), Gaps = 41/155 (26%)

Query: 52   IHAAK---IQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRN-------- 100
            IHA K   +QSD  YK   E  KGI   P+D + +V+AK+   L+SD  YR         
Sbjct: 3370 IHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDTIYRQRPETLKFT 3429

Query: 101  ----------------------YLHQWT-------CLPDQNDVIQAKKAYDLQSDNLYKS 131
                                  Y   W         +PD  +++ AK      SD LYK 
Sbjct: 3430 SITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPDTPEIMLAKLNRINYSDKLYKL 3489

Query: 132  DLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYR 165
             LE  K  G+ L   ++ +   K ++++ ++  Y+
Sbjct: 3490 ALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYK 3524



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 37/161 (22%), Positives = 69/161 (42%), Gaps = 9/161 (5%)

Query: 42   LQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNY 101
            L D    + A  A  +QSD  YK   E  +GI   P+  + + + K+   ++SD  YR  
Sbjct: 3606 LPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAGEILSDRKYRQP 3665

Query: 102  LHQ--WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLL 159
              Q  +TC+ D  +++ AK      S +LY    +  K    +   + +++  K+    +
Sbjct: 3666 ADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPDTPDILLAKSNSANI 3725

Query: 160  NERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRD 200
            +++LY    +  K             + +A+ I   + SRD
Sbjct: 3726 SQKLYTKGWDESKMKD-------YDLRADAISIKSAKASRD 3759



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 46/217 (21%), Positives = 94/217 (43%), Gaps = 53/217 (24%)

Query: 29   YRKQLGHHMGFRTLQDDPKSV-WAIHAAKIQSDREYKKAYEK-SKGIHNTPLDMMSIVQA 86
            YR+   H+    TL  D  +V  + +A +IQSD  YK  +    KGI   P++ + + +A
Sbjct: 1649 YRQSYHHY----TLLPDALNVEHSRNAMQIQSDNLYKSDFTNWMKGIGWVPIESLEVEKA 1704

Query: 87   KKCQVLVSDIDYRN------------------------------YLHQWT-------CLP 109
            KK   ++S+  YR                               Y  +W         +P
Sbjct: 1705 KKAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDKTTIHVMP 1764

Query: 110  DQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYR--- 165
            D  D++ ++      SD LYK+  E  K  G+ L   ++ +   + ++++ ++  Y+   
Sbjct: 1765 DTPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAY 1824

Query: 166  --IKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRD 200
               K + + F S+ D P++    ++ +Q+++++  R+
Sbjct: 1825 EQAKGKHIGFRSLEDDPKL----VHFMQVAKMQSDRE 1857



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 46/206 (22%), Positives = 84/206 (40%), Gaps = 48/206 (23%)

Query: 39   FRTLQDDPKSVWAIHAAKIQSDREYKKAY-EKSKGIHNTPLDMMSIVQAKKCQVLVSDID 97
            +  L D      A +  +IQSD +YK  Y +  KGI   PL  +   + KK   ++S+  
Sbjct: 1900 YNMLPDAMSFELAKNMMQIQSDNQYKADYADFMKGIGWLPLGSLEAEKNKKAMEIISEKK 1959

Query: 98   YRN------------------------------YLHQWTC-------LPDQNDVIQAKKA 120
            YR                               Y   W         +PD   +I AK  
Sbjct: 1960 YRQHPDTLKYSTLMDSMNMVLAQNNAKIMNEHLYKQAWEADKTKVHIMPDIPQIILAKAN 2019

Query: 121  YDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYRI-----KPEALKFT 174
                SD LYK  LE  K  G+ L   ++ +   K ++++ ++  Y+      K + + F 
Sbjct: 2020 AINMSDKLYKLSLEESKKKGYDLRPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFR 2079

Query: 175  SIVDTPEVIQAKINAVQISEVEKSRD 200
            S+ D P++    ++++Q+++++  R+
Sbjct: 2080 SLEDDPKL----VHSMQVAKMQSDRE 2101



 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 42/154 (27%), Positives = 65/154 (42%), Gaps = 10/154 (6%)

Query: 42   LQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNY 101
            +QD P+ +      K  S   YK+       I  TP     +++ K+ Q  +S + Y+  
Sbjct: 6133 VQDTPEILRVKENQKNFSSVLYKEDVSPGTAIGKTP----EMMRVKQTQDHISSVKYKEA 6188

Query: 102  LHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNE 161
            + Q T +PD  +V + K+     S  +YK +L    G G     + E+ RVK  Q   + 
Sbjct: 6189 IGQGTPIPDLPEVKRVKETQKHISSVMYKENL----GTGIPTTVTPEIERVKRNQENFSS 6244

Query: 162  RLYRIKPEALKFTSIVDTPEVIQAKINAVQISEV 195
             LY  K    K      TPE+ + K N    S V
Sbjct: 6245 VLY--KENLGKGIPTPITPEMERVKRNQENFSSV 6276



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 43/151 (28%), Positives = 67/151 (44%), Gaps = 16/151 (10%)

Query: 24   KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
            KYK   +  L ++  FR++ D P+ V A   +  QSD +YK+ + K+KG +    D   I
Sbjct: 4388 KYK---KNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPDTPHI 4444

Query: 84   VQAKKCQVLVSDIDYR-----NYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG 138
              +K    L S I Y+        + +T       ++ AK A  + S+  YK   E  KG
Sbjct: 4445 SHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKG 4504

Query: 139  -------IGWLPEGSVEVMRVKNAQNLLNER 162
                   IG  P G V  +  +  ++ LN R
Sbjct: 4505 HYLAGKVIGEFP-GVVHCLDFQKMRSALNYR 4534



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 32/123 (26%), Positives = 59/123 (47%), Gaps = 7/123 (5%)

Query: 23   YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
            YKYKE + +       F+ + D P +    +A ++ ++++Y+  YE+ K  ++  +D   
Sbjct: 5369 YKYKEVFERTKSD---FKYVADSPINRHFKYATQLMNEKKYRADYEQRKDKYHLVVDEPR 5425

Query: 83   IVQAKKCQVLVSDIDYR-NY---LHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG 138
             + AK     +S I YR NY     ++T + D  + ++  K     SD LYK +    K 
Sbjct: 5426 HLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPEHLRTTKVNKQISDILYKLEYNKAKP 5485

Query: 139  IGW 141
             G+
Sbjct: 5486 RGY 5488



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 41/152 (26%), Positives = 64/152 (42%), Gaps = 8/152 (5%)

Query: 20   VPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHN--TP 77
            V   KYK+  +K L     + TL +   +V      K  SD  YKK + K KG  N    
Sbjct: 5647 VSENKYKDHVKKHLAQG-SYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIM 5705

Query: 78   LDMMSIVQAKKCQVLVSDIDYR----NYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL 133
            L+   +  A +     SD+ YR      LH +T + D+ D+ +A +A    S+  Y++  
Sbjct: 5706 LEPPEVKHAMEVAKKQSDVAYRKDAKENLH-YTTVADRPDIKKATQAAKQASEVEYRAKH 5764

Query: 134  EWLKGIGWLPEGSVEVMRVKNAQNLLNERLYR 165
                  G    G  ++   K A  L ++  YR
Sbjct: 5765 RKEGSHGLSMLGRPDIEMAKKAAKLSSQVKYR 5796



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 34/117 (29%), Positives = 58/117 (49%), Gaps = 7/117 (5%)

Query: 54   AAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLH----QWTCLP 109
            A++I S+++Y++  +++K    +  D M IV AK      SD  YR        Q   +P
Sbjct: 2438 ASEIISEKKYRQPPDRNK--FTSIPDAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMP 2495

Query: 110  DQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYR 165
            D  D++ AK      SD LY+   E LK  G+ LP  ++ +   K ++ + +E  Y+
Sbjct: 2496 DTPDIVLAKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIASEYKYK 2552



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 54/207 (26%), Positives = 85/207 (41%), Gaps = 17/207 (8%)

Query: 39   FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY 98
            F +++D P +V +      +SD  YK   E+    +N P D+   +QAK     +S+  Y
Sbjct: 993  FTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKYNLPPDLPQFIQAKVNAYNISENMY 1052

Query: 99   RNYLHQ-----WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG--IGWLP-EGSVEVM 150
            +  L       +    D   +  AK A    SD  YK D E  KG  +G+   +   +++
Sbjct: 1053 KADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDYEKAKGKMVGFQSLQDDPKLV 1112

Query: 151  RVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNFNVRHYGSY 210
               N   + ++R Y  K +  K  S  +TP  +    N V   + +    N N +H  S 
Sbjct: 1113 HYMNVAKIQSDREY--KKDYEKTKSKYNTPHDM---FNVVAAKKAQDVVSNVNYKH--SL 1165

Query: 211  LDQKQLGPAQQWELSELSAMWTYPSDN 237
                 L  A   ELS+   M    SDN
Sbjct: 1166 HHYTYLPDAMDLELSK--NMMQIQSDN 1190



 Score = 37.7 bits (86), Expect = 0.009
 Identities = 38/142 (26%), Positives = 59/142 (41%), Gaps = 8/142 (5%)

Query: 39   FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY 98
            F ++ D P  V A    K  SD  YK   E  K  +    D+   +QAK     +SD+ Y
Sbjct: 1237 FTSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHKYTMSPDLPQFLQAKCNAYNISDVCY 1296

Query: 99   RNYLHQW-----TCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG--IGWLP-EGSVEVM 150
            +   H         L D   +  AK + ++ SD  YK   E  KG  +G+   +   +++
Sbjct: 1297 KRDWHDLIAKGNNVLGDAIPITAAKASRNIASDYKYKEAYEKSKGKHVGFRSLQDDPKLV 1356

Query: 151  RVKNAQNLLNERLYRIKPEALK 172
               N   L ++R Y+   E  K
Sbjct: 1357 HYMNVAKLQSDREYKKNYENTK 1378



 Score = 37.4 bits (85), Expect = 0.011
 Identities = 56/207 (27%), Positives = 85/207 (41%), Gaps = 21/207 (10%)

Query: 5   CLFPKPHTYDLS----LPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSD 60
           C FP+  T +      L +   + YK    K       F  + D P  + A    K  SD
Sbjct: 716 CYFPQTITQEYEAIKKLDQCKDHTYKVHPDKTK-----FTAVTDSPVLLQAQLNTKQLSD 770

Query: 61  REYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY-----RNYLHQWTCLPDQNDVI 115
             YK  +E  K   + P D    +Q +     +SD  Y     ++   ++    D   ++
Sbjct: 771 LNYKAKHEGEKFKCHIPADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLL 830

Query: 116 QAKKAYDLQSDNLYKSDLEWLKG--IGWLPEGSVEVM--RVKNAQNLLNERLYRIKPEAL 171
            AK      SD +YK D E  KG  IG L       M   +K A+N  ++R YR   E  
Sbjct: 831 AAKANTKNTSDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKN-QSDREYRKDYEKS 889

Query: 172 K--FTSIVDTPEVIQAKINAVQISEVE 196
           K  +T+ +D  +V QAK +    S+V+
Sbjct: 890 KTIYTAPLDMLQVTQAKKSQAIASDVD 916



 Score = 37.4 bits (85), Expect = 0.011
 Identities = 38/168 (22%), Positives = 70/168 (41%), Gaps = 10/168 (5%)

Query: 39   FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY 98
            +  + D P  V A+ +    S+ +YK+ Y + K  + T L+ +   + +  + L S   Y
Sbjct: 4645 YNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYTTVLETVDYDRTRNLKNLYSSNLY 4704

Query: 99   RNYLHQWTC----LPDQN-DVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP---EGSVEVM 150
            +    +       LP     +  AK    L S   Y+ + E  K +  LP   +      
Sbjct: 4705 KEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLPRSVDDDPNTA 4764

Query: 151  RVKNAQNLLNERLYR--IKPEALKFTSIVDTPEVIQAKINAVQISEVE 196
            R      L  +RLYR   +   +K   + D  E++ AK +  ++SE++
Sbjct: 4765 RCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVTAKDSQKKVSEID 4812



 Score = 36.2 bits (82), Expect = 0.025
 Identities = 33/162 (20%), Positives = 65/162 (40%), Gaps = 38/162 (23%)

Query: 42   LQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRN- 100
            L D    + A  A  +QSD  YK   +  +GI   P+  M +V+ K+   ++SD  YR  
Sbjct: 3120 LPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRAAEILSDNIYRQP 3179

Query: 101  -----------------------------YLHQWT-------CLPDQNDVIQAKKAYDLQ 124
                                         Y   W         +PD  +++ A++     
Sbjct: 3180 PDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINY 3239

Query: 125  SDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYR 165
            S++LY+  +E  K  G+ L   ++ ++  K ++++ ++  Y+
Sbjct: 3240 SESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYK 3281



 Score = 32.3 bits (72), Expect = 0.37
 Identities = 44/154 (28%), Positives = 67/154 (43%), Gaps = 12/154 (7%)

Query: 39  FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY 98
           F  + D P  + A   +K  SD  YK  +E  K   + P D  + +Q K     +SD  Y
Sbjct: 502 FTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHIPPDTPAFIQHKVNAYNLSDNLY 561

Query: 99  -----RNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG--IGWLPEGSVEVM- 150
                ++   ++    D   ++ AK      SD +YK D E  KG  IG L       M 
Sbjct: 562 KQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKGKMIGVLSINDDPKML 621

Query: 151 -RVKNAQNLLNERLYRIKPEALKFTSI--VDTPE 181
             +K A+N  ++RLY+   E  K  S+   +TP+
Sbjct: 622 HSLKVAKN-QSDRLYKENYEKTKAKSMNYCETPK 654



 Score = 32.3 bits (72), Expect = 0.37
 Identities = 39/161 (24%), Positives = 75/161 (46%), Gaps = 20/161 (12%)

Query: 13   YDLSLPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKG 72
            YDL    +  YK    + K +G  M   +L+D+        A +I SD  Y++  ++ K 
Sbjct: 2647 YDLQSDNL--YKSDLQWLKGIGW-MTSGSLEDEKNK----RATQILSDHVYRQHPDQFK- 2698

Query: 73   IHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWT-------CLPDQNDVIQAKKAYDLQS 125
              ++ +D + +V AK   + ++   +R Y   W         +PD  +V+ AK+     S
Sbjct: 2699 -FSSLMDSIPMVLAKNNAITMN---HRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYS 2754

Query: 126  DNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYR 165
            + LYK  LE  K  G+ +   ++ +   K ++++ +E  Y+
Sbjct: 2755 EKLYKLGLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKYK 2795



 Score = 30.0 bits (66), Expect = 1.8
 Identities = 31/138 (22%), Positives = 59/138 (42%), Gaps = 5/138 (3%)

Query: 63   YKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYD 122
            YK+   K+     TP     + + K+ Q  +S + Y+  L + T  P   ++ + K+  +
Sbjct: 6309 YKENVGKATATPVTP----EMQRVKRNQENISSVLYKENLGKATPTPFTPEMERVKRNQE 6364

Query: 123  LQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEV 182
              S  LYK ++         PE        +N  ++L    +R + +  K   ++DTPE+
Sbjct: 6365 NFSSVLYKENMRKATPTPVTPEMERAKRNQENISSVLYSDSFRKQIQG-KAAYVLDTPEM 6423

Query: 183  IQAKINAVQISEVEKSRD 200
             + +     IS V+   D
Sbjct: 6424 RRVRETQRHISTVKYHED 6441


>gi|46049092 nebulin-related anchoring protein isoform C [Homo
           sapiens]
          Length = 1695

 Score =  159 bits (401), Expect = 3e-39
 Identities = 77/184 (41%), Positives = 118/184 (64%)

Query: 24  KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
           KYKE Y +  G  +G + +Q D +   ++  +K+QS+ EYKK +E +K   +  LDM+ +
Sbjct: 786 KYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHL 845

Query: 84  VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143
           V A+K Q L +D+ Y+   H +T LP    V  AKKAY LQSDN Y++D++W+KG+GW+ 
Sbjct: 846 VHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVA 905

Query: 144 EGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNFN 203
            GS+ V + K A  L++E+ YR  P+ALKFTSI DTPE++QA+I+  Q  +        N
Sbjct: 906 TGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGEN 965

Query: 204 VRHY 207
           ++H+
Sbjct: 966 IKHH 969



 Score =  145 bits (365), Expect = 4e-35
 Identities = 74/163 (45%), Positives = 106/163 (65%), Gaps = 4/163 (2%)

Query: 24  KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
           KYKE Y K  G  MG      D + + ++  AK+ S+ EYKK +E+SK   + P+DM++I
Sbjct: 547 KYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNI 602

Query: 84  VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143
             AKK Q L SD+DYR  LH++T LP+      AKKAY LQS+  YK+DL W+KG+GWL 
Sbjct: 603 RHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLT 662

Query: 144 EGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAK 186
           EGS+ + + K A  L++E+ YR + + LKFTS+ D+ ++  AK
Sbjct: 663 EGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAK 705



 Score =  142 bits (359), Expect = 2e-34
 Identities = 69/169 (40%), Positives = 108/169 (63%)

Query: 20   VPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLD 79
            +  YKYKE + K  G  +G R+L+DD     +++A  +QSD  YKK +E SK   + PLD
Sbjct: 1025 ISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLD 1084

Query: 80   MMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGI 139
            M ++V AKK Q L S+ DY++ L Q+T L +   +  AKKA+ LQS+NLY+SDL +++G+
Sbjct: 1085 MAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGV 1144

Query: 140  GWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKIN 188
              +  G++E+   K A  L++E  YR  P + K+T++ DTP ++ AK +
Sbjct: 1145 ACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFS 1193



 Score =  130 bits (327), Expect = 1e-30
 Identities = 67/186 (36%), Positives = 115/186 (61%), Gaps = 1/186 (0%)

Query: 23   YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
            + Y+  + K+ G  +G ++++DDP+        ++QS+ +Y++    S+   + P+DM+ 
Sbjct: 1271 FLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVH 1330

Query: 83   IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142
            +V AK  Q L SD DYR   H++T LP+   +  AKKA+ LQS+  YKSDL  +KGIGWL
Sbjct: 1331 LVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWL 1390

Query: 143  PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE-VEKSRDN 201
               S ++   K A  L++E  YR KP+++KFT++VD+P+++ AK + +  +E + +S D 
Sbjct: 1391 ALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDA 1450

Query: 202  FNVRHY 207
             ++  Y
Sbjct: 1451 ESLHRY 1456



 Score =  118 bits (296), Expect = 4e-27
 Identities = 61/163 (37%), Positives = 92/163 (56%), Gaps = 12/163 (7%)

Query: 12   TYDLSLPEVP------------SYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQS 59
            +YD  L  +P             ++YKE + +  G  +G+R++ DDP+    ++  ++QS
Sbjct: 1491 SYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQS 1550

Query: 60   DREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKK 119
            D EYKK + KS+   ++  D   ++QAK+ Q L SD+ YR  L Q TC P+Q  +  A+K
Sbjct: 1551 DNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQK 1610

Query: 120  AYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNER 162
            A+ LQSD  YKSDL   +G+GW P GS +V   + A  L N R
Sbjct: 1611 AHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELANAR 1653



 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 54/190 (28%), Positives = 90/190 (47%), Gaps = 15/190 (7%)

Query: 24  KYKEGYRKQLGHHMGFRTLQD--DPKSVWAIHAAKIQSDREYKKAYEKSKGI---HNTPL 78
           +Y +GY ++   H G  +      P    A  A ++ SD +Y++ + K KG    H+ P 
Sbjct: 293 QYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPA 352

Query: 79  -DMMSIVQAKKCQVLVSDIDYR-NYLH----QWTCLPDQNDVIQAKKAYDLQSDNLYKSD 132
            D + + QA+    LVS+  Y+ NY +    ++  +      + A K   L S+  YK+D
Sbjct: 353 QDNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKAD 412

Query: 133 LEWLKGIGWLPEGSVEVMRVKNAQNL--LNERLYRIKPEALKFTSIVDTPEVIQAKINAV 190
            +    I      +      + A  L  L +  YR   + LK++S+ DTP+++QAKINA 
Sbjct: 413 YK--HDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQ 470

Query: 191 QISEVEKSRD 200
           Q+S V    D
Sbjct: 471 QLSHVNYRAD 480



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 46/175 (26%), Positives = 75/175 (42%), Gaps = 41/175 (23%)

Query: 29  YRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKK 88
           YRK+L     +  L +D K+ WA  A  +QS+ +YK      KG+       +++ QAKK
Sbjct: 617 YRKKLHE---YTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKK 673

Query: 89  CQVLVSDIDYRNYLHQ--WTCLPDQNDVIQAKKAYDLQS--------------------- 125
              LVS+ +YR  + +  +T + D + +  AKK+ +LQS                     
Sbjct: 674 AGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDE 733

Query: 126 --------------DNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYR 165
                         + LYKS  E  K  G+ L   S+  +  K  ++L +E  Y+
Sbjct: 734 PLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYK 788



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 34/132 (25%), Positives = 62/132 (46%), Gaps = 8/132 (6%)

Query: 12  TYDLSLPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSK 71
           +Y  ++  VP    K+   +Q    + + ++ D P+ V A   A+  S   Y+  YEK+K
Sbjct: 429 SYQTAMKLVP---LKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNK 485

Query: 72  GIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQ-----WTCLPDQNDVIQAKKAYDLQSD 126
             +  P D+  +V+AK    L S++ Y+    +     +    D   ++ AK + +L S+
Sbjct: 486 LNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASN 545

Query: 127 NLYKSDLEWLKG 138
             YK + E  KG
Sbjct: 546 IKYKEEYEKTKG 557



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 55/242 (22%), Positives = 94/242 (38%), Gaps = 45/242 (18%)

Query: 10   PHTYDLSLPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEK 69
            P T ++   +  S    E   +Q  H   +  + D P  + A  + +I ++R YK A E 
Sbjct: 1149 PGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGED 1208

Query: 70   SKGIHNTPLDMMSIVQAKKCQVLVSDIDY----RNYLHQWTCLPDQNDVIQAKKAY-DLQ 124
            ++  +   L +   ++AK     +SD  Y    RN   Q   L  +    QA +A  D+ 
Sbjct: 1209 ARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIA 1268

Query: 125  SDNLYK--------------------------------SDLEWLKGIG------WLPEGS 146
            SD LY+                                S+L++ +G         LP   
Sbjct: 1269 SDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDM 1328

Query: 147  VEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNFNVRH 206
            V ++  KNAQ L ++  YR +    KFT++ +  ++  AK      SE+    D   ++ 
Sbjct: 1329 VHLVHAKNAQALASDHDYRTQYH--KFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKG 1386

Query: 207  YG 208
             G
Sbjct: 1387 IG 1388



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 42/180 (23%), Positives = 72/180 (40%), Gaps = 39/180 (21%)

Query: 20  VPSYKYKEGYRKQL-GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPL 78
           V   KYKE Y+  + G + G      D +++ A+    + S+  YK  Y+     +N P 
Sbjct: 368 VSENKYKENYQNHMRGRYEGVGM---DRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPA 424

Query: 79  DMMSIVQAKKCQVLVSDIDYRNYLHQ--WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWL 136
            +    Q     V + D +YR  + +  ++ + D   ++QAK      S   Y++D E  
Sbjct: 425 TLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYE-- 482

Query: 137 KGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVE 196
                              +N LN            +T   D P++++AK NA   SEV+
Sbjct: 483 -------------------KNKLN------------YTLPQDVPQLVKAKTNAKLFSEVK 511



 Score = 37.7 bits (86), Expect = 0.009
 Identities = 23/76 (30%), Positives = 41/76 (53%), Gaps = 4/76 (5%)

Query: 24  KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
           +YK G+ +++     F T+ D P+ + +   A++QSD  Y + YE+ +G  + P  +   
Sbjct: 192 EYKRGHDERISR---FSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPA 248

Query: 84  VQ-AKKCQVLVSDIDY 98
            Q AK+   L SD+ Y
Sbjct: 249 YQIAKRANELASDVRY 264



 Score = 37.0 bits (84), Expect = 0.015
 Identities = 36/149 (24%), Positives = 52/149 (34%), Gaps = 44/149 (29%)

Query: 23   YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
            + Y+  Y K       F  L +D K  WA  A  +QS+  YK      KGI    L    
Sbjct: 1344 HDYRTQYHK-------FTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQ 1396

Query: 83   IVQAKKCQVLVSDIDYRNY-------------------------------------LHQW 105
            +  AKK   L+S+  YR                                       LH++
Sbjct: 1397 MESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRY 1456

Query: 106  TCLPDQNDVIQAKKAYDLQSDNLYKSDLE 134
            T +PD  D  +A+      SD +Y++  E
Sbjct: 1457 TLIPDHPDFTRARLNALHLSDKVYRNSWE 1485



 Score = 35.4 bits (80), Expect = 0.043
 Identities = 31/108 (28%), Positives = 52/108 (48%), Gaps = 9/108 (8%)

Query: 108 LPDQNDV--IQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEV-MRVKNAQNLLNERLY 164
           LPD   V  ++A+K+   +    Y  D E  +G G  P        R K A  L ++  Y
Sbjct: 138 LPDPEIVRMVEARKSLGEE----YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEY 193

Query: 165 RIKPEAL--KFTSIVDTPEVIQAKINAVQISEVEKSRDNFNVRHYGSY 210
           +   +    +F+++VDTPE++++K  A   S+V  + D    R  GS+
Sbjct: 194 KRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSF 241



 Score = 31.2 bits (69), Expect = 0.82
 Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 9/119 (7%)

Query: 60  DREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYR-----NYLHQWTCLPDQNDV 114
           D  Y+++ +K K  +++  D   IVQAK     +S ++YR     N L+ +T   D   +
Sbjct: 441 DANYRQSIDKLK--YSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLN-YTLPQDVPQL 497

Query: 115 IQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYRIKPEALK 172
           ++AK    L S+  YK   E  KG G+ +   ++ ++  K +  L +   Y+ + E  K
Sbjct: 498 VKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTK 556


>gi|46049105 nebulin-related anchoring protein isoform S [Homo
            sapiens]
          Length = 1730

 Score =  159 bits (401), Expect = 3e-39
 Identities = 77/184 (41%), Positives = 118/184 (64%)

Query: 24   KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
            KYKE Y +  G  +G + +Q D +   ++  +K+QS+ EYKK +E +K   +  LDM+ +
Sbjct: 821  KYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHL 880

Query: 84   VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143
            V A+K Q L +D+ Y+   H +T LP    V  AKKAY LQSDN Y++D++W+KG+GW+ 
Sbjct: 881  VHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVA 940

Query: 144  EGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNFN 203
             GS+ V + K A  L++E+ YR  P+ALKFTSI DTPE++QA+I+  Q  +        N
Sbjct: 941  TGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGEN 1000

Query: 204  VRHY 207
            ++H+
Sbjct: 1001 IKHH 1004



 Score =  145 bits (365), Expect = 4e-35
 Identities = 74/163 (45%), Positives = 106/163 (65%), Gaps = 4/163 (2%)

Query: 24  KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
           KYKE Y K  G  MG      D + + ++  AK+ S+ EYKK +E+SK   + P+DM++I
Sbjct: 582 KYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNI 637

Query: 84  VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143
             AKK Q L SD+DYR  LH++T LP+      AKKAY LQS+  YK+DL W+KG+GWL 
Sbjct: 638 RHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLT 697

Query: 144 EGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAK 186
           EGS+ + + K A  L++E+ YR + + LKFTS+ D+ ++  AK
Sbjct: 698 EGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAK 740



 Score =  142 bits (359), Expect = 2e-34
 Identities = 69/169 (40%), Positives = 108/169 (63%)

Query: 20   VPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLD 79
            +  YKYKE + K  G  +G R+L+DD     +++A  +QSD  YKK +E SK   + PLD
Sbjct: 1060 ISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLD 1119

Query: 80   MMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGI 139
            M ++V AKK Q L S+ DY++ L Q+T L +   +  AKKA+ LQS+NLY+SDL +++G+
Sbjct: 1120 MAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGV 1179

Query: 140  GWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKIN 188
              +  G++E+   K A  L++E  YR  P + K+T++ DTP ++ AK +
Sbjct: 1180 ACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFS 1228



 Score =  130 bits (327), Expect = 1e-30
 Identities = 67/186 (36%), Positives = 115/186 (61%), Gaps = 1/186 (0%)

Query: 23   YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
            + Y+  + K+ G  +G ++++DDP+        ++QS+ +Y++    S+   + P+DM+ 
Sbjct: 1306 FLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVH 1365

Query: 83   IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142
            +V AK  Q L SD DYR   H++T LP+   +  AKKA+ LQS+  YKSDL  +KGIGWL
Sbjct: 1366 LVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWL 1425

Query: 143  PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE-VEKSRDN 201
               S ++   K A  L++E  YR KP+++KFT++VD+P+++ AK + +  +E + +S D 
Sbjct: 1426 ALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDA 1485

Query: 202  FNVRHY 207
             ++  Y
Sbjct: 1486 ESLHRY 1491



 Score =  118 bits (296), Expect = 4e-27
 Identities = 61/163 (37%), Positives = 92/163 (56%), Gaps = 12/163 (7%)

Query: 12   TYDLSLPEVP------------SYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQS 59
            +YD  L  +P             ++YKE + +  G  +G+R++ DDP+    ++  ++QS
Sbjct: 1526 SYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQS 1585

Query: 60   DREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKK 119
            D EYKK + KS+   ++  D   ++QAK+ Q L SD+ YR  L Q TC P+Q  +  A+K
Sbjct: 1586 DNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQK 1645

Query: 120  AYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNER 162
            A+ LQSD  YKSDL   +G+GW P GS +V   + A  L N R
Sbjct: 1646 AHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELANAR 1688



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 52/185 (28%), Positives = 80/185 (43%), Gaps = 10/185 (5%)

Query: 24  KYKEGYRKQLGH-HMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
           KY++ + K  G  H      QD+     A    K+ S+ EYKK  E S+G      +   
Sbjct: 333 KYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQ 392

Query: 83  IVQAKKCQVLVSDIDYR-NYLH----QWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLK 137
                K     SD  Y+ NY +    ++  +      + A K   L S+  YK+D +   
Sbjct: 393 FRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYK--H 450

Query: 138 GIGWLPEGSVEVMRVKNAQNL--LNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEV 195
            I      +      + A  L  L +  YR   + LK++S+ DTP+++QAKINA Q+S V
Sbjct: 451 DIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHV 510

Query: 196 EKSRD 200
               D
Sbjct: 511 NYRAD 515



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 46/175 (26%), Positives = 75/175 (42%), Gaps = 41/175 (23%)

Query: 29  YRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKK 88
           YRK+L     +  L +D K+ WA  A  +QS+ +YK      KG+       +++ QAKK
Sbjct: 652 YRKKLHE---YTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKK 708

Query: 89  CQVLVSDIDYRNYLHQ--WTCLPDQNDVIQAKKAYDLQS--------------------- 125
              LVS+ +YR  + +  +T + D + +  AKK+ +LQS                     
Sbjct: 709 AGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDE 768

Query: 126 --------------DNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYR 165
                         + LYKS  E  K  G+ L   S+  +  K  ++L +E  Y+
Sbjct: 769 PLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYK 823



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 34/132 (25%), Positives = 62/132 (46%), Gaps = 8/132 (6%)

Query: 12  TYDLSLPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSK 71
           +Y  ++  VP    K+   +Q    + + ++ D P+ V A   A+  S   Y+  YEK+K
Sbjct: 464 SYQTAMKLVP---LKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNK 520

Query: 72  GIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQ-----WTCLPDQNDVIQAKKAYDLQSD 126
             +  P D+  +V+AK    L S++ Y+    +     +    D   ++ AK + +L S+
Sbjct: 521 LNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASN 580

Query: 127 NLYKSDLEWLKG 138
             YK + E  KG
Sbjct: 581 IKYKEEYEKTKG 592



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 55/242 (22%), Positives = 94/242 (38%), Gaps = 45/242 (18%)

Query: 10   PHTYDLSLPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEK 69
            P T ++   +  S    E   +Q  H   +  + D P  + A  + +I ++R YK A E 
Sbjct: 1184 PGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGED 1243

Query: 70   SKGIHNTPLDMMSIVQAKKCQVLVSDIDY----RNYLHQWTCLPDQNDVIQAKKAY-DLQ 124
            ++  +   L +   ++AK     +SD  Y    RN   Q   L  +    QA +A  D+ 
Sbjct: 1244 ARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIA 1303

Query: 125  SDNLYK--------------------------------SDLEWLKGIG------WLPEGS 146
            SD LY+                                S+L++ +G         LP   
Sbjct: 1304 SDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDM 1363

Query: 147  VEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNFNVRH 206
            V ++  KNAQ L ++  YR +    KFT++ +  ++  AK      SE+    D   ++ 
Sbjct: 1364 VHLVHAKNAQALASDHDYRTQYH--KFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKG 1421

Query: 207  YG 208
             G
Sbjct: 1422 IG 1423



 Score = 37.7 bits (86), Expect = 0.009
 Identities = 52/234 (22%), Positives = 102/234 (43%), Gaps = 52/234 (22%)

Query: 24  KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
           +YK G+ +++     F T+ D P+ + +   A++QSD  Y + YE+ +G  + P  +   
Sbjct: 192 EYKRGHDERISR---FSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPA 248

Query: 84  VQ-AKKCQVLVSDIDY-RNYLHQWTCL-----------------------PDQNDVIQ-- 116
            Q AK+   L SD+ Y + Y  +   +                       P++ +  +  
Sbjct: 249 YQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGK 308

Query: 117 -------------AKKAYDLQSDNLYKSDLEWLKGIGW---LP-EGSVEVMRVKNAQNLL 159
                        AKKA++L SD  Y+ D   +KG      LP + ++ + + ++   L+
Sbjct: 309 GSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLV 368

Query: 160 NERLYRIKPEALKFTSI--VDTPEVIQ-AKINAVQISEVEKSRDNFNVRHYGSY 210
           +E  Y+   E+ +  SI   +TP+    +KI+  + +   K ++N+     G Y
Sbjct: 369 SEVEYKKDLESSRGHSINYCETPQFRNVSKIS--KFTSDNKYKENYQNHMRGRY 420



 Score = 37.7 bits (86), Expect = 0.009
 Identities = 41/176 (23%), Positives = 71/176 (40%), Gaps = 39/176 (22%)

Query: 24  KYKEGYRKQL-GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
           KYKE Y+  + G + G      D +++ A+    + S+  YK  Y+     +N P  +  
Sbjct: 407 KYKENYQNHMRGRYEGVGM---DRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTP 463

Query: 83  IVQAKKCQVLVSDIDYRNYLHQ--WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIG 140
             Q     V + D +YR  + +  ++ + D   ++QAK      S   Y++D E      
Sbjct: 464 SYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYE------ 517

Query: 141 WLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVE 196
                          +N LN            +T   D P++++AK NA   SEV+
Sbjct: 518 ---------------KNKLN------------YTLPQDVPQLVKAKTNAKLFSEVK 546



 Score = 37.0 bits (84), Expect = 0.015
 Identities = 36/149 (24%), Positives = 52/149 (34%), Gaps = 44/149 (29%)

Query: 23   YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
            + Y+  Y K       F  L +D K  WA  A  +QS+  YK      KGI    L    
Sbjct: 1379 HDYRTQYHK-------FTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQ 1431

Query: 83   IVQAKKCQVLVSDIDYRNY-------------------------------------LHQW 105
            +  AKK   L+S+  YR                                       LH++
Sbjct: 1432 MESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRY 1491

Query: 106  TCLPDQNDVIQAKKAYDLQSDNLYKSDLE 134
            T +PD  D  +A+      SD +Y++  E
Sbjct: 1492 TLIPDHPDFTRARLNALHLSDKVYRNSWE 1520



 Score = 35.4 bits (80), Expect = 0.043
 Identities = 31/108 (28%), Positives = 52/108 (48%), Gaps = 9/108 (8%)

Query: 108 LPDQNDV--IQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEV-MRVKNAQNLLNERLY 164
           LPD   V  ++A+K+   +    Y  D E  +G G  P        R K A  L ++  Y
Sbjct: 138 LPDPEIVRMVEARKSLGEE----YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEY 193

Query: 165 RIKPEAL--KFTSIVDTPEVIQAKINAVQISEVEKSRDNFNVRHYGSY 210
           +   +    +F+++VDTPE++++K  A   S+V  + D    R  GS+
Sbjct: 194 KRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSF 241



 Score = 31.2 bits (69), Expect = 0.82
 Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 9/119 (7%)

Query: 60  DREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYR-----NYLHQWTCLPDQNDV 114
           D  Y+++ +K K  +++  D   IVQAK     +S ++YR     N L+ +T   D   +
Sbjct: 476 DANYRQSIDKLK--YSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLN-YTLPQDVPQL 532

Query: 115 IQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYRIKPEALK 172
           ++AK    L S+  YK   E  KG G+ +   ++ ++  K +  L +   Y+ + E  K
Sbjct: 533 VKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTK 591


>gi|5453758 nebulette sarcomeric isoform [Homo sapiens]
          Length = 1014

 Score = 62.4 bits (150), Expect = 3e-10
 Identities = 49/158 (31%), Positives = 79/158 (50%), Gaps = 14/158 (8%)

Query: 51  AIHAAKIQSDREYKKAYE---KSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQ--- 104
           A  A+++ S++EYKK  E   K KG+     D + +  AKK   + S+ DY+  L     
Sbjct: 437 AKRASEMASEKEYKKDLESIIKGKGMQ-AGTDTLEMQHAKKAAEIASEKDYKRDLETEIK 495

Query: 105 ---WTCLPDQNDVIQAKKAYDLQSDNLYKSDLE-WLKGIGWLPEGSV-EVMRVKNAQNLL 159
                   D  DV +AKKA ++ S   YK DLE  +KG G      + +++R K    + 
Sbjct: 496 GKGMQVSTDTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIY 555

Query: 160 NERLYRIKPEAL--KFTSIVDTPEVIQAKINAVQISEV 195
           ++R Y+ + E +   +++I DTPE+ + K     IS V
Sbjct: 556 SQRKYKDEAEKMLSNYSTIADTPEIQRIKTTQQNISAV 593



 Score = 55.1 bits (131), Expect = 5e-08
 Identities = 46/171 (26%), Positives = 78/171 (45%), Gaps = 9/171 (5%)

Query: 29  YRKQLGHHM---GFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQ 85
           Y+K L + +   G +   D P  + A   ++I S R+YK   EK    ++T  D   I +
Sbjct: 523 YKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSNYSTIADTPEIQR 582

Query: 86  AKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEG 145
            K  Q  +S + Y+  +   T + D  ++ + KK     S   YK +++    I   PE 
Sbjct: 583 IKTTQQNISAVFYKKEVGAGTAVKDSPEIERVKKNQQNISSVKYKEEIKHATAISDPPE- 641

Query: 146 SVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVE 196
              + RVK  Q  ++   Y  K +  K T +  TPE+ + + N  Q+S V+
Sbjct: 642 ---LKRVKENQKNISNLQY--KEQNYKATPVSMTPEIERVRRNQEQLSAVK 687



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 46/162 (28%), Positives = 81/162 (50%), Gaps = 15/162 (9%)

Query: 52  IHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLP-- 109
           + A+K+ S REYKK +E++KG+++   D +  +  K   VL S + Y+    +    P  
Sbjct: 293 LKASKMLSGREYKKLFEENKGMYHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPML 352

Query: 110 ---DQNDVIQAKKAYDLQSDNLYKSDLE-WLKGIGWLP-EGSVEVMRVKNAQNLLNERLY 164
              +      +K+A  +QS+ +YK D E  +KG   L  + + E + VK   NLL E+ Y
Sbjct: 353 EFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLDLDKTPEFLHVKYITNLLREKEY 412

Query: 165 R------IKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRD 200
           +      IK + ++  S  +  ++ +AK  +   SE E  +D
Sbjct: 413 KKDLENEIKGKGMELNS--EVLDIQRAKRASEMASEKEYKKD 452



 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 52/193 (26%), Positives = 91/193 (47%), Gaps = 20/193 (10%)

Query: 24  KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKS-KGIHNTPLDMM- 81
           KYKE Y K  G  M      + P    +  A K+QS++ YK+ +EK  KG  +  LD   
Sbjct: 338 KYKEEYEKNKGKPM--LEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLDLDKTP 395

Query: 82  SIVQAKKCQVLVSDIDYRNYLHQ------WTCLPDQNDVIQAKKAYDLQSDNLYKSDLE- 134
             +  K    L+ + +Y+  L             +  D+ +AK+A ++ S+  YK DLE 
Sbjct: 396 EFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKEYKKDLES 455

Query: 135 WLKGIGW-LPEGSVEVMRVKNAQNLLNERLYR------IKPEALKFTSIVDTPEVIQAKI 187
            +KG G      ++E+   K A  + +E+ Y+      IK + ++ ++  DT +V +AK 
Sbjct: 456 IIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVST--DTLDVQRAKK 513

Query: 188 NAVQISEVEKSRD 200
            +   S+ +  +D
Sbjct: 514 ASEMASQKQYKKD 526



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 46/172 (26%), Positives = 71/172 (41%), Gaps = 13/172 (7%)

Query: 24  KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
           KYK+   K L +   + T+ D P+    I   K          Y+K  G      D   I
Sbjct: 559 KYKDEAEKMLSN---YSTIADTPE----IQRIKTTQQNISAVFYKKEVGAGTAVKDSPEI 611

Query: 84  VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143
            + KK Q  +S + Y+  +   T + D  ++ + K+     S+  YK        +   P
Sbjct: 612 ERVKKNQQNISSVKYKEEIKHATAISDPPELKRVKENQKNISNLQYKEQNYKATPVSMTP 671

Query: 144 EGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEV 195
               E+ RV+  Q  L+   Y  K E  + T+I D PE+ +AK N   IS V
Sbjct: 672 ----EIERVRRNQEQLSAVKY--KGELQRGTAISDPPELKRAKENQKNISNV 717



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 36/136 (26%), Positives = 62/136 (45%), Gaps = 7/136 (5%)

Query: 62  EYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAY 121
           +YK   ++   I + P     + +AK+ Q  +S++ YR  L + T L    ++ + KK  
Sbjct: 687 KYKGELQRGTAISDPP----ELKRAKENQKNISNVYYRGQLGRATTLSVTPEMERVKKNQ 742

Query: 122 DLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALK---FTSIVD 178
           +  S   Y  D + +KG   L   +  +  VK AQN ++   Y    E  K   FT +VD
Sbjct: 743 ENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVD 802

Query: 179 TPEVIQAKINAVQISE 194
            P   + + N   +S+
Sbjct: 803 DPVTERVRKNTQVVSD 818



 Score = 29.3 bits (64), Expect = 3.1
 Identities = 48/189 (25%), Positives = 77/189 (40%), Gaps = 14/189 (7%)

Query: 19  EVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKA---YEKSKGIHN 75
           EV  ++    YRK +     +    D P    A   +KI S+ EYKK      K   +  
Sbjct: 153 EVNKHQSNISYRKDVQDTHTYSAELDRPDIKMATQISKIISNAEYKKGQGIMNKEPAVIG 212

Query: 76  TPLDMMSIVQAKKCQVLVS-----DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYK 130
            P D    V+A K    +      D + ++  H +  L +     Q + A  L S+  YK
Sbjct: 213 RP-DFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPL-ESASFRQNQLAATLASNVKYK 270

Query: 131 SDLEWLKG-IGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALK--FTSIVDTPEVIQAKI 187
            D++ +   +  LP   + +  V  A  +L+ R Y+   E  K  +    D  E +  K 
Sbjct: 271 KDIQNMHDPVSDLP-NLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEHLHHKG 329

Query: 188 NAVQISEVE 196
           NAV  S+V+
Sbjct: 330 NAVLQSQVK 338



 Score = 28.5 bits (62), Expect = 5.3
 Identities = 35/165 (21%), Positives = 70/165 (42%), Gaps = 12/165 (7%)

Query: 68  EKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYL----HQWTCLPDQNDVIQAKKAYDL 123
           E+ +  +   ++ +S+  A+KC  L+SDI Y+        + T + D   +   K     
Sbjct: 24  EEDQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAF 83

Query: 124 QSDNLYKSDL--EWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALK----FTSIV 177
            S+  YK  +  +    +      +++ +       L +E  Y+ K +A K    +  + 
Sbjct: 84  ISEAKYKGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKGFSDYAHMK 143

Query: 178 DTPEVIQA-KINAVQISEVEKSRDNFNVRHYGSYLDQKQLGPAQQ 221
           + PEV  A ++N  Q S +   +D  +   Y + LD+  +  A Q
Sbjct: 144 EPPEVKHAMEVNKHQ-SNISYRKDVQDTHTYSAELDRPDIKMATQ 187



 Score = 28.1 bits (61), Expect = 6.9
 Identities = 23/106 (21%), Positives = 43/106 (40%), Gaps = 6/106 (5%)

Query: 39  FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY 98
           ++ + +D     A    ++ SD  YK+ ++KSK       D   +   K     +S+  Y
Sbjct: 30  YKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFISEAKY 89

Query: 99  RNYLHQ------WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG 138
           +  +        +  +P   D + A +   LQS+  YK   +  KG
Sbjct: 90  KGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKG 135


>gi|47087157 nebulette non-muscle isoform [Homo sapiens]
          Length = 270

 Score = 37.4 bits (85), Expect = 0.011
 Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 4/94 (4%)

Query: 105 WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERL 163
           +T + D  + ++ K+  +LQS   YK D E  KG G+ +   + E+ R+K  Q  ++   
Sbjct: 62  FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121

Query: 164 YRIKPEALK---FTSIVDTPEVIQAKINAVQISE 194
           Y    E  K   FT +VD P   + + N   +S+
Sbjct: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSD 155



 Score = 33.9 bits (76), Expect = 0.13
 Identities = 24/98 (24%), Positives = 48/98 (48%), Gaps = 6/98 (6%)

Query: 39  FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGI-HNTPLDMMSIVQAKKCQVLVSDID 97
           F T+ D P+++     +++QS  +YK+ +E+SKG   +   D   + + K+ Q  +S++ 
Sbjct: 62  FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121

Query: 98  YRNYLHQ-----WTCLPDQNDVIQAKKAYDLQSDNLYK 130
           Y     +     +T + D     + +K   + SD  YK
Sbjct: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 27.7 bits (60), Expect = 9.0
 Identities = 18/54 (33%), Positives = 27/54 (50%), Gaps = 6/54 (11%)

Query: 153 KNAQNLLNERLYRIKPEA------LKFTSIVDTPEVIQAKINAVQISEVEKSRD 200
           K A N+ N + Y  KP          FT++ DTPE ++ K  +   S+V+  RD
Sbjct: 36  KMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRD 89


>gi|5453710 LIM and SH3 protein 1 [Homo sapiens]
          Length = 261

 Score = 36.6 bits (83), Expect = 0.019
 Identities = 30/134 (22%), Positives = 59/134 (44%), Gaps = 3/134 (2%)

Query: 2   HLSCLFPKPHTYDLSLPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDR 61
           H +C   +     L++     Y+ K+ Y         F  + D P+++     +++QS  
Sbjct: 26  HKACFHCETCKMTLNMKNYKGYE-KKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQV 84

Query: 62  EYKKAYEKSKGI-HNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKA 120
            YK+ +EK+KG   +   D   + + KK Q  +S+I Y     +    P   + ++ ++ 
Sbjct: 85  RYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPERR 144

Query: 121 YDLQSDNLYKSDLE 134
            D Q  + Y+  LE
Sbjct: 145 -DSQDGSSYRRPLE 157



 Score = 28.5 bits (62), Expect = 5.3
 Identities = 17/61 (27%), Positives = 33/61 (54%), Gaps = 1/61 (1%)

Query: 105 WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERL 163
           +T + D  + ++ K+  +LQS   YK + E  KG G+ +   + E+ R+K  Q+ ++   
Sbjct: 62  FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121

Query: 164 Y 164
           Y
Sbjct: 122 Y 122


>gi|127138957 zinc finger protein 537 [Homo sapiens]
          Length = 1081

 Score = 30.4 bits (67), Expect = 1.4
 Identities = 22/91 (24%), Positives = 43/91 (47%), Gaps = 6/91 (6%)

Query: 147 VEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNFNVRH 206
           VE         LL+E++  +   A  FTS  +TP  I  K+N     EV+K +   + + 
Sbjct: 426 VETPVTPTITTLLDEKVQSVPLAATTFTSPSNTPASISPKLNVEVKKEVDKEKAVTDEK- 484

Query: 207 YGSYLDQKQLGPAQQWELSELSAMWTYPSDN 237
                 +++  P ++ E  ++S+ + Y ++N
Sbjct: 485 -----PKQKDKPGEEEEKCDISSKYHYLTEN 510


>gi|222352158 carboxypeptidase 3, cytosolic [Homo sapiens]
          Length = 920

 Score = 29.6 bits (65), Expect = 2.4
 Identities = 20/75 (26%), Positives = 31/75 (41%), Gaps = 17/75 (22%)

Query: 172 KFTSIVDTPEVIQ---------AKINAVQISEVEKSRDNFNVRHYGSYLDQKQLGPAQQW 222
           K   IV T E++Q           +   QI ++   R NF ++H        QL PA   
Sbjct: 737 KDKGIVQTQEILQYLLPIVHSTKNMQTTQIKQLFNPRTNFQIQH--------QLNPATCR 788

Query: 223 ELSELSAMWTYPSDN 237
            + + S  WT P ++
Sbjct: 789 NIKKYSTSWTAPRNH 803


>gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
           sapiens]
          Length = 1710

 Score = 29.6 bits (65), Expect = 2.4
 Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 6/79 (7%)

Query: 91  VLVSDIDYRNYL--HQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVE 148
           V + DI+ RN +  H+WT     +   + K    L +  +   D  +L G+ W   G  E
Sbjct: 560 VYLGDINSRNMIRTHEWT----HHQTKRLKFNILLTTYEILLKDKAFLGGLNWAFIGVDE 615

Query: 149 VMRVKNAQNLLNERLYRIK 167
             R+KN  +LL + L   K
Sbjct: 616 AHRLKNDDSLLYKTLIDFK 634


>gi|110349721 titin isoform novex-3 [Homo sapiens]
          Length = 5604

 Score = 28.9 bits (63), Expect = 4.1
 Identities = 13/29 (44%), Positives = 15/29 (51%), Gaps = 2/29 (6%)

Query: 8    PKPHTY--DLSLPEVPSYKYKEGYRKQLG 34
            PKPH Y     +P    Y+YK  Y KQ G
Sbjct: 1109 PKPHVYWKKSGVPLTTGYRYKVSYNKQTG 1137


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 28.9 bits (63), Expect = 4.1
 Identities = 13/29 (44%), Positives = 15/29 (51%), Gaps = 2/29 (6%)

Query: 8    PKPHTY--DLSLPEVPSYKYKEGYRKQLG 34
            PKPH Y     +P    Y+YK  Y KQ G
Sbjct: 1109 PKPHVYWKKSGVPLTTGYRYKVSYNKQTG 1137


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score = 28.9 bits (63), Expect = 4.1
 Identities = 13/29 (44%), Positives = 15/29 (51%), Gaps = 2/29 (6%)

Query: 8    PKPHTY--DLSLPEVPSYKYKEGYRKQLG 34
            PKPH Y     +P    Y+YK  Y KQ G
Sbjct: 1063 PKPHVYWKKSGVPLTTGYRYKVSYNKQTG 1091


>gi|110349713 titin isoform novex-1 [Homo sapiens]
          Length = 27051

 Score = 28.9 bits (63), Expect = 4.1
 Identities = 13/29 (44%), Positives = 15/29 (51%), Gaps = 2/29 (6%)

Query: 8    PKPHTY--DLSLPEVPSYKYKEGYRKQLG 34
            PKPH Y     +P    Y+YK  Y KQ G
Sbjct: 1063 PKPHVYWKKSGVPLTTGYRYKVSYNKQTG 1091


>gi|110349715 titin isoform N2-B [Homo sapiens]
          Length = 26926

 Score = 28.9 bits (63), Expect = 4.1
 Identities = 13/29 (44%), Positives = 15/29 (51%), Gaps = 2/29 (6%)

Query: 8    PKPHTY--DLSLPEVPSYKYKEGYRKQLG 34
            PKPH Y     +P    Y+YK  Y KQ G
Sbjct: 1063 PKPHVYWKKSGVPLTTGYRYKVSYNKQTG 1091


>gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens]
          Length = 561

 Score = 28.5 bits (62), Expect = 5.3
 Identities = 34/159 (21%), Positives = 69/159 (43%), Gaps = 16/159 (10%)

Query: 58  QSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQA 117
           Q  +E K+ YE ++   N      S V+ + CQ+           H+  C+  Q D +  
Sbjct: 294 QQIKEMKEMYENAEAKVNNSTGKWSCVEERICQL----------QHENPCIEQQLDDVHQ 343

Query: 118 KKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIV 177
           K+ +     N+ +  +E  K    L E + ++M   N  + L E L++ + E  +   +V
Sbjct: 344 KEDHKEIVTNIQRGFIESGKKDLMLEEKNKKLM---NECDHLKESLFQYEREKAERVVVV 400

Query: 178 DTPEVIQAKINAVQISEVEKSRDNFNVRHYGSYLDQKQL 216
              +  +A  +  +++ +E   +   + HY   LD+ Q+
Sbjct: 401 RQLQQ-EAADSLKKLTMLESPLE--GISHYHINLDETQV 436


>gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens]
          Length = 1844

 Score = 28.5 bits (62), Expect = 5.3
 Identities = 27/107 (25%), Positives = 44/107 (41%), Gaps = 15/107 (14%)

Query: 76  TPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEW 135
           TPL+M S V+ KK +  V      N  HQ   +  +N+      + D + D    +D   
Sbjct: 100 TPLEMFSNVEFKKKRKRV------NLSHQLNNIKTENEAPIEISSDDSKEDYSLNNDFV- 152

Query: 136 LKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEV 182
                   E S  V+R K    +L E +   K +    TS+ ++ +V
Sbjct: 153 --------ESSTSVLRYKKQVEVLAENIQDTKSQPNTMTSLQNSKKV 191


>gi|45446749 kinesin family member 5A [Homo sapiens]
          Length = 1032

 Score = 28.5 bits (62), Expect = 5.3
 Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 7/76 (9%)

Query: 53  HAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAK-KCQVLVSDIDYRNYLHQWTCLPDQ 111
           H AKI+S  EY ++ E  K       D +S   AK + Q  V ++  ++        PD 
Sbjct: 636 HEAKIRSLTEYMQSVELKKRHLEESYDSLSDELAKLQAQETVHEVALKDKE------PDT 689

Query: 112 NDVIQAKKAYDLQSDN 127
            D  + KKA +LQ ++
Sbjct: 690 QDADEVKKALELQMES 705


>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
          Length = 2325

 Score = 28.5 bits (62), Expect = 5.3
 Identities = 36/160 (22%), Positives = 79/160 (49%), Gaps = 17/160 (10%)

Query: 75  NTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQA-KKAYDLQSD-NLYKSD 132
           N  L   +++Q + C+ L SD++ +N L +   +    ++ +A +K Y+L+ +   YK D
Sbjct: 307 NKSLKEEAMLQKQSCEELKSDLNTKNELLKQKTI----ELTRACQKQYELEQELAFYKID 362

Query: 133 LEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQI 192
            ++ + + + P    E+ +  +    + +  Y+    A + + I+D+ + +Q K    ++
Sbjct: 363 AKF-EPLNYYPSEYAEIDKAPDESPYIGKSRYKRNMFATE-SYIIDSAQAVQIK----KM 416

Query: 193 SEVEKSR-DNFNVRHY----GSYLDQKQLGPAQQWELSEL 227
              E+ R D+ N+R +        D+++   A Q  LSEL
Sbjct: 417 EPDEQLRNDHMNLRGHTPLDTQLEDKEKKISAAQTRLSEL 456


>gi|19923424 myotubularin related protein 9 [Homo sapiens]
          Length = 549

 Score = 27.7 bits (60), Expect = 9.0
 Identities = 11/34 (32%), Positives = 18/34 (52%)

Query: 21 PSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHA 54
          P Y   EG     GHH+   + QD+ + +W +H+
Sbjct: 20 PFYPAVEGTLCLTGHHLILSSRQDNTEELWLLHS 53


>gi|112380630 leiomodin 1 (smooth muscle) [Homo sapiens]
          Length = 600

 Score = 27.7 bits (60), Expect = 9.0
 Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 3/85 (3%)

Query: 143 PEGSVEV-MRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDN 201
           P+GSV V +R +N     +  +Y    EA+      +T +++Q +++  +  +VE   D 
Sbjct: 41  PDGSVPVGLRQRNQTEKQSTGVYN--REAMLNFCEKETKKLMQREMSMDESKQVETKTDA 98

Query: 202 FNVRHYGSYLDQKQLGPAQQWELSE 226
            N    G    +K LGP +  +L +
Sbjct: 99  KNGEERGRDASKKALGPRRDSDLGK 123


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,292,605
Number of Sequences: 37866
Number of extensions: 378514
Number of successful extensions: 1193
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 876
Number of HSP's gapped (non-prelim): 155
length of query: 237
length of database: 18,247,518
effective HSP length: 99
effective length of query: 138
effective length of database: 14,498,784
effective search space: 2000832192
effective search space used: 2000832192
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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