BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Homo sapiens] (622 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Hom... 1240 0.0 gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Hom... 1240 0.0 gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [H... 1240 0.0 gi|39932589 Rho GTPase activating protein 18 [Homo sapiens] 414 e-115 gi|59710113 Rho GTPase activating protein 28 isoform a [Homo sap... 302 7e-82 gi|59710111 Rho GTPase activating protein 28 isoform b [Homo sap... 253 4e-67 gi|41281907 StAR-related lipid transfer (START) domain containin... 92 2e-18 gi|16445031 StAR-related lipid transfer (START) domain containin... 92 2e-18 gi|41281898 StAR-related lipid transfer (START) domain containin... 92 2e-18 gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] 90 7e-18 gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens] 88 2e-17 gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens] 88 2e-17 gi|67906814 Rho GTPase activating protein 19 [Homo sapiens] 87 5e-17 gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sap... 87 5e-17 gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens] 87 6e-17 gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapi... 87 6e-17 gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapi... 87 6e-17 gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo sap... 86 8e-17 gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo sap... 86 8e-17 gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens] 84 4e-16 gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens] 84 4e-16 gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa... 84 5e-16 gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap... 84 5e-16 gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] 83 9e-16 gi|229094128 active breakpoint cluster region-related protein i... 82 1e-15 gi|38679957 active breakpoint cluster region-related protein is... 82 1e-15 gi|38679954 active breakpoint cluster region-related protein is... 82 1e-15 gi|21264337 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom... 82 2e-15 gi|5803145 ralA binding protein 1 [Homo sapiens] 81 3e-15 gi|188497642 ARHGAP15 [Homo sapiens] 80 4e-15 >gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Homo sapiens] Length = 622 Score = 1240 bits (3208), Expect = 0.0 Identities = 622/622 (100%), Positives = 622/622 (100%) Query: 1 MDQLPQKNLLRLHPAGSAGCSTGVESSSMDGFWMEVEQIQQRDELREEDSGGNEGQLPEE 60 MDQLPQKNLLRLHPAGSAGCSTGVESSSMDGFWMEVEQIQQRDELREEDSGGNEGQLPEE Sbjct: 1 MDQLPQKNLLRLHPAGSAGCSTGVESSSMDGFWMEVEQIQQRDELREEDSGGNEGQLPEE 60 Query: 61 GEAESQWLQDTGLSGLLGGLGLDGDHQELLSTLTQTQVAAVCRRLDIYARSVRRQHKTPV 120 GEAESQWLQDTGLSGLLGGLGLDGDHQELLSTLTQTQVAAVCRRLDIYARSVRRQHKTPV Sbjct: 61 GEAESQWLQDTGLSGLLGGLGLDGDHQELLSTLTQTQVAAVCRRLDIYARSVRRQHKTPV 120 Query: 121 RDVRDVFGVFNSGKMSSENGDSGMKGAQLSSGASKFPPAAEPGGLQEQAGREEAFNMDSA 180 RDVRDVFGVFNSGKMSSENGDSGMKGAQLSSGASKFPPAAEPGGLQEQAGREEAFNMDSA Sbjct: 121 RDVRDVFGVFNSGKMSSENGDSGMKGAQLSSGASKFPPAAEPGGLQEQAGREEAFNMDSA 180 Query: 181 YSEQAAVLLQRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRKVPSLALIE 240 YSEQAAVLLQRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRKVPSLALIE Sbjct: 181 YSEQAAVLLQRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRKVPSLALIE 240 Query: 241 LTALCDILGLDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLE 300 LTALCDILGLDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLE Sbjct: 241 LTALCDILGLDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLE 300 Query: 301 KRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPL 360 KRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPL Sbjct: 301 KRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPL 360 Query: 361 LTAEYLPAFAVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMT 420 LTAEYLPAFAVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMT Sbjct: 361 LTAEYLPAFAVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMT 420 Query: 421 LRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQVR 480 LRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQVR Sbjct: 421 LRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQVR 480 Query: 481 KLNDSSSRRPQLCDAGLKTWLRRMHADRDKAGDGLEATPKVAKIQVVWPIKDPLKVPLTP 540 KLNDSSSRRPQLCDAGLKTWLRRMHADRDKAGDGLEATPKVAKIQVVWPIKDPLKVPLTP Sbjct: 481 KLNDSSSRRPQLCDAGLKTWLRRMHADRDKAGDGLEATPKVAKIQVVWPIKDPLKVPLTP 540 Query: 541 STKVAHVLRQFTEHLSPGSKGQEDSEDMDSLLLHHRSMESANILLYEVGGNINEHRLDPD 600 STKVAHVLRQFTEHLSPGSKGQEDSEDMDSLLLHHRSMESANILLYEVGGNINEHRLDPD Sbjct: 541 STKVAHVLRQFTEHLSPGSKGQEDSEDMDSLLLHHRSMESANILLYEVGGNINEHRLDPD 600 Query: 601 AYLLDLYRANPHGEWVLKQNPT 622 AYLLDLYRANPHGEWVLKQNPT Sbjct: 601 AYLLDLYRANPHGEWVLKQNPT 622 >gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Homo sapiens] Length = 622 Score = 1240 bits (3208), Expect = 0.0 Identities = 622/622 (100%), Positives = 622/622 (100%) Query: 1 MDQLPQKNLLRLHPAGSAGCSTGVESSSMDGFWMEVEQIQQRDELREEDSGGNEGQLPEE 60 MDQLPQKNLLRLHPAGSAGCSTGVESSSMDGFWMEVEQIQQRDELREEDSGGNEGQLPEE Sbjct: 1 MDQLPQKNLLRLHPAGSAGCSTGVESSSMDGFWMEVEQIQQRDELREEDSGGNEGQLPEE 60 Query: 61 GEAESQWLQDTGLSGLLGGLGLDGDHQELLSTLTQTQVAAVCRRLDIYARSVRRQHKTPV 120 GEAESQWLQDTGLSGLLGGLGLDGDHQELLSTLTQTQVAAVCRRLDIYARSVRRQHKTPV Sbjct: 61 GEAESQWLQDTGLSGLLGGLGLDGDHQELLSTLTQTQVAAVCRRLDIYARSVRRQHKTPV 120 Query: 121 RDVRDVFGVFNSGKMSSENGDSGMKGAQLSSGASKFPPAAEPGGLQEQAGREEAFNMDSA 180 RDVRDVFGVFNSGKMSSENGDSGMKGAQLSSGASKFPPAAEPGGLQEQAGREEAFNMDSA Sbjct: 121 RDVRDVFGVFNSGKMSSENGDSGMKGAQLSSGASKFPPAAEPGGLQEQAGREEAFNMDSA 180 Query: 181 YSEQAAVLLQRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRKVPSLALIE 240 YSEQAAVLLQRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRKVPSLALIE Sbjct: 181 YSEQAAVLLQRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRKVPSLALIE 240 Query: 241 LTALCDILGLDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLE 300 LTALCDILGLDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLE Sbjct: 241 LTALCDILGLDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLE 300 Query: 301 KRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPL 360 KRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPL Sbjct: 301 KRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPL 360 Query: 361 LTAEYLPAFAVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMT 420 LTAEYLPAFAVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMT Sbjct: 361 LTAEYLPAFAVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMT 420 Query: 421 LRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQVR 480 LRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQVR Sbjct: 421 LRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQVR 480 Query: 481 KLNDSSSRRPQLCDAGLKTWLRRMHADRDKAGDGLEATPKVAKIQVVWPIKDPLKVPLTP 540 KLNDSSSRRPQLCDAGLKTWLRRMHADRDKAGDGLEATPKVAKIQVVWPIKDPLKVPLTP Sbjct: 481 KLNDSSSRRPQLCDAGLKTWLRRMHADRDKAGDGLEATPKVAKIQVVWPIKDPLKVPLTP 540 Query: 541 STKVAHVLRQFTEHLSPGSKGQEDSEDMDSLLLHHRSMESANILLYEVGGNINEHRLDPD 600 STKVAHVLRQFTEHLSPGSKGQEDSEDMDSLLLHHRSMESANILLYEVGGNINEHRLDPD Sbjct: 541 STKVAHVLRQFTEHLSPGSKGQEDSEDMDSLLLHHRSMESANILLYEVGGNINEHRLDPD 600 Query: 601 AYLLDLYRANPHGEWVLKQNPT 622 AYLLDLYRANPHGEWVLKQNPT Sbjct: 601 AYLLDLYRANPHGEWVLKQNPT 622 >gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [Homo sapiens] Length = 622 Score = 1240 bits (3208), Expect = 0.0 Identities = 622/622 (100%), Positives = 622/622 (100%) Query: 1 MDQLPQKNLLRLHPAGSAGCSTGVESSSMDGFWMEVEQIQQRDELREEDSGGNEGQLPEE 60 MDQLPQKNLLRLHPAGSAGCSTGVESSSMDGFWMEVEQIQQRDELREEDSGGNEGQLPEE Sbjct: 1 MDQLPQKNLLRLHPAGSAGCSTGVESSSMDGFWMEVEQIQQRDELREEDSGGNEGQLPEE 60 Query: 61 GEAESQWLQDTGLSGLLGGLGLDGDHQELLSTLTQTQVAAVCRRLDIYARSVRRQHKTPV 120 GEAESQWLQDTGLSGLLGGLGLDGDHQELLSTLTQTQVAAVCRRLDIYARSVRRQHKTPV Sbjct: 61 GEAESQWLQDTGLSGLLGGLGLDGDHQELLSTLTQTQVAAVCRRLDIYARSVRRQHKTPV 120 Query: 121 RDVRDVFGVFNSGKMSSENGDSGMKGAQLSSGASKFPPAAEPGGLQEQAGREEAFNMDSA 180 RDVRDVFGVFNSGKMSSENGDSGMKGAQLSSGASKFPPAAEPGGLQEQAGREEAFNMDSA Sbjct: 121 RDVRDVFGVFNSGKMSSENGDSGMKGAQLSSGASKFPPAAEPGGLQEQAGREEAFNMDSA 180 Query: 181 YSEQAAVLLQRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRKVPSLALIE 240 YSEQAAVLLQRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRKVPSLALIE Sbjct: 181 YSEQAAVLLQRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRKVPSLALIE 240 Query: 241 LTALCDILGLDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLE 300 LTALCDILGLDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLE Sbjct: 241 LTALCDILGLDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLE 300 Query: 301 KRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPL 360 KRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPL Sbjct: 301 KRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPL 360 Query: 361 LTAEYLPAFAVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMT 420 LTAEYLPAFAVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMT Sbjct: 361 LTAEYLPAFAVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMT 420 Query: 421 LRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQVR 480 LRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQVR Sbjct: 421 LRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQVR 480 Query: 481 KLNDSSSRRPQLCDAGLKTWLRRMHADRDKAGDGLEATPKVAKIQVVWPIKDPLKVPLTP 540 KLNDSSSRRPQLCDAGLKTWLRRMHADRDKAGDGLEATPKVAKIQVVWPIKDPLKVPLTP Sbjct: 481 KLNDSSSRRPQLCDAGLKTWLRRMHADRDKAGDGLEATPKVAKIQVVWPIKDPLKVPLTP 540 Query: 541 STKVAHVLRQFTEHLSPGSKGQEDSEDMDSLLLHHRSMESANILLYEVGGNINEHRLDPD 600 STKVAHVLRQFTEHLSPGSKGQEDSEDMDSLLLHHRSMESANILLYEVGGNINEHRLDPD Sbjct: 541 STKVAHVLRQFTEHLSPGSKGQEDSEDMDSLLLHHRSMESANILLYEVGGNINEHRLDPD 600 Query: 601 AYLLDLYRANPHGEWVLKQNPT 622 AYLLDLYRANPHGEWVLKQNPT Sbjct: 601 AYLLDLYRANPHGEWVLKQNPT 622 >gi|39932589 Rho GTPase activating protein 18 [Homo sapiens] Length = 663 Score = 414 bits (1065), Expect = e-115 Identities = 239/618 (38%), Positives = 365/618 (59%), Gaps = 45/618 (7%) Query: 24 VESSSMDGFWMEVEQIQQRDELREEDSGGNEGQLPEEGEAESQWLQDTGLSGLLGGLGLD 83 ++ SM+ +W+E+E I++ E +ED + P+EGE E +WL++ GLS L G Sbjct: 70 LDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKEAGLSNLFGESA-- 127 Query: 84 GDHQE---LLSTLTQTQVAAVCRRLDIYARSVRRQHKT-PVRDVRDVFGVFNSGKMSSEN 139 GD QE LSTLT+TQ AAV +R++ ++++R+++K + DVRD+F + S E Sbjct: 128 GDPQESIVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIFA---QQRESKET 184 Query: 140 GDSGMKGAQLSSGASKFPPAAEPGGL----------QEQAGREEAFNMDSAYSEQAAVLL 189 G + L + +K+ + +E E N++ +++EQA Sbjct: 185 APGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVSFAEQALNQK 244 Query: 190 QRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRKVPSLALIELTALCDILG 249 + S+ + S +LP F +PK + G TRIGDL+ QDM+KV LALIELTAL D+LG Sbjct: 245 ESSK-EKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYDVLG 303 Query: 250 LDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGI 309 ++LK+ KA K K ++ LF VPL +LLE D + +P ++PL+ Q L+S +E+RGL+ EG+ Sbjct: 304 IELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGL 363 Query: 310 LRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAF 369 LR+PG+ R+K L Q+LE FY G F+W+ V +DA+ LLK FIR+LP PLL+ EYL AF Sbjct: 364 LRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAF 423 Query: 370 AVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMA 429 V N+P KQ+LQ L+LL+++LP+ NR+ LKALLEFL++V+ ++ NKMT+ NV+ VMA Sbjct: 424 QAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMA 483 Query: 430 PNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQVRKLNDSSSRR 489 PNLF+ K + +E +A G A + +++ YQ LLWT+ F+V QVRK N + ++ Sbjct: 484 PNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNTENHKK 543 Query: 490 PQLCDAGLKTWLRRMHADR------DKAGDGLEATPKVAKIQVVWPIKDPLKVPLTPSTK 543 + +K L++M DR DK+ + + V ++Q K + + LT K Sbjct: 544 DK---RAMKKLLKKMAYDREKYEKQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELK 600 Query: 544 VAHVLRQFTEHLSPGSKGQEDSEDMDSLLLHHRSMESANILLYEVGGNINEHRLDPDAYL 603 + VL +F S + ++++ + LYE+GGNI E LD D Y+ Sbjct: 601 ASDVLARFLSQESGVA----------------QTLKKGEVFLYEIGGNIGERCLDDDTYM 644 Query: 604 LDLYRANPHGEWVLKQNP 621 DLY+ NP+ EWV+K P Sbjct: 645 KDLYQLNPNAEWVIKSKP 662 >gi|59710113 Rho GTPase activating protein 28 isoform a [Homo sapiens] Length = 570 Score = 302 bits (773), Expect = 7e-82 Identities = 181/462 (39%), Positives = 265/462 (57%), Gaps = 37/462 (8%) Query: 173 EAFNMDSAYSEQAAVLLQRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRK 232 E + + +YSE L+R++ + L KF V K R G+T GDLS +DM+K Sbjct: 125 EELSFEVSYSEMVTEALKRNKLKKSEIKKEDYV-LTKFNVQKTRFGLTEAGDLSAEDMKK 183 Query: 233 VPSLALIELTALCDILGLDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVL 292 + L+LIELTA D G+ LKR+K K K + +FGVPL LL+ D K P +VPLVL Sbjct: 184 IRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVL 243 Query: 293 QALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRF 352 Q +E+ GL+ EGI R+ G A+VK ++L+ F A F WD++ H +A+ +LK F Sbjct: 244 QKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAF 303 Query: 353 IRKLPTPLLTAEYLPAF-AVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVV 411 R+LPT L EY+PAF +++ P++K + Q LHL+++ LP+ NR+A +AL+ F KV+ Sbjct: 304 FRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVI 363 Query: 412 AREQHNKMTLRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTV 471 A E N+M+L N+STVMAPNLF + K +E LA AA ++++M+ YQ +LW V Sbjct: 364 ANESKNRMSLWNISTVMAPNLFFSRS---KHSDYEELLLANTAAHIIRLMLKYQKILWKV 420 Query: 472 ASFLVAQVRKLNDSSS-RRPQLCDAGLKTWLRRMHADRD----KAGDGLEATPKVAK--- 523 SFL+ QVR++N+++ + QL ++ LRR +R+ K L+ +P + Sbjct: 421 PSFLITQVRRMNEATMLLKKQL--PSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSD 478 Query: 524 -----IQVVWPI--KDPLKVPLTPSTKVAHVLRQFTEHLSPGSKGQEDSEDMDSLLLHHR 576 I+V P+ K + + L TK +L +F S GS Sbjct: 479 VPEGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYENSHGSS---------------E 523 Query: 577 SMESANILLYEVGGNINEHRLDPDAYLLDLYRANPHGEWVLK 618 ++ N LYE+GGNI EH LDPDAY+LD+YR NP EWV+K Sbjct: 524 CIKIQNQRLYEIGGNIGEHCLDPDAYILDVYRINPQAEWVIK 565 >gi|59710111 Rho GTPase activating protein 28 isoform b [Homo sapiens] Length = 563 Score = 253 bits (646), Expect = 4e-67 Identities = 144/354 (40%), Positives = 216/354 (61%), Gaps = 14/354 (3%) Query: 173 EAFNMDSAYSEQAAVLLQRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRK 232 E + + +YSE L+R++ + L KF V K R G+T GDLS +DM+K Sbjct: 125 EELSFEVSYSEMVTEALKRNKLKKSEIKKEDYV-LTKFNVQKTRFGLTEAGDLSAEDMKK 183 Query: 233 VPSLALIELTALCDILGLDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVL 292 + L+LIELTA D G+ LKR+K K K + +FGVPL LL+ D K P +VPLVL Sbjct: 184 IRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVL 243 Query: 293 QALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRF 352 Q +E+ GL+ EGI R+ G A+VK ++L+ F A F WD++ H +A+ +LK F Sbjct: 244 QKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAF 303 Query: 353 IRKLPTPLLTAEYLPAF-AVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVV 411 R+LPT L EY+PAF +++ P++K + Q LHL+++ LP+ NR+A +AL+ F KV+ Sbjct: 304 FRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVI 363 Query: 412 AREQHNKMTLRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTV 471 A E N+M+L N+STVMAPNLF + K +E LA AA ++++M+ YQ +LW V Sbjct: 364 ANESKNRMSLWNISTVMAPNLFFSRS---KHSDYEELLLANTAAHIIRLMLKYQKILWKV 420 Query: 472 ASFLVAQVRKLNDSSS-RRPQLCDAGLKTWLRRMHADRDKAGDGLEATPKVAKI 524 SFL+ QVR++N+++ + QL ++ LRR +R+ A+PK +K+ Sbjct: 421 PSFLITQVRRMNEATMLLKKQL--PSVRKLLRRKTLERE------TASPKTSKV 466 >gi|41281907 StAR-related lipid transfer (START) domain containing 13 isoform beta [Homo sapiens] Length = 1105 Score = 91.7 bits (226), Expect = 2e-18 Identities = 74/242 (30%), Positives = 119/242 (49%), Gaps = 22/242 (9%) Query: 252 LKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILR 311 +KR K +K + +FGVPL ++ + LP + +Q L L LD G+ R Sbjct: 639 MKRMKVPDYK--DKAVFGVPLIVHVQRTGQPLPQS-----IQQALRYLRSNCLDQVGLFR 691 Query: 312 VPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAV 371 G ++R+ L Q E + ++++ D +D++K+F R LP PL T + F Sbjct: 692 KSGVKSRIHALRQMNEN--FPENVNYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLH 749 Query: 372 VPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPN 431 + + +QRLQ + IL+L + NR L+ LL FL VV + N+MT N++ +AP+ Sbjct: 750 IYQYVSKEQRLQAVQAAILLLADENREVLQTLLCFLNDVVNLVEENQMTPMNLAVCLAPS 809 Query: 432 LF-LHQGRPPKLPKGKEKQLAEG------------AAEVVQIMVHYQDLLWTVASFLVAQ 478 LF L+ + P+ +K+ A G AA+ + M+ D L+ V LVAQ Sbjct: 810 LFHLNLLKKESSPRVIQKKYATGKPDQKDLNENLAAAQGLAHMIMECDRLFEVPHELVAQ 869 Query: 479 VR 480 R Sbjct: 870 SR 871 >gi|16445031 StAR-related lipid transfer (START) domain containing 13 isoform gamma [Homo sapiens] Length = 995 Score = 91.7 bits (226), Expect = 2e-18 Identities = 74/242 (30%), Positives = 119/242 (49%), Gaps = 22/242 (9%) Query: 252 LKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILR 311 +KR K +K + +FGVPL ++ + LP + +Q L L LD G+ R Sbjct: 529 MKRMKVPDYK--DKAVFGVPLIVHVQRTGQPLPQS-----IQQALRYLRSNCLDQVGLFR 581 Query: 312 VPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAV 371 G ++R+ L Q E + ++++ D +D++K+F R LP PL T + F Sbjct: 582 KSGVKSRIHALRQMNEN--FPENVNYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLH 639 Query: 372 VPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPN 431 + + +QRLQ + IL+L + NR L+ LL FL VV + N+MT N++ +AP+ Sbjct: 640 IYQYVSKEQRLQAVQAAILLLADENREVLQTLLCFLNDVVNLVEENQMTPMNLAVCLAPS 699 Query: 432 LF-LHQGRPPKLPKGKEKQLAEG------------AAEVVQIMVHYQDLLWTVASFLVAQ 478 LF L+ + P+ +K+ A G AA+ + M+ D L+ V LVAQ Sbjct: 700 LFHLNLLKKESSPRVIQKKYATGKPDQKDLNENLAAAQGLAHMIMECDRLFEVPHELVAQ 759 Query: 479 VR 480 R Sbjct: 760 SR 761 >gi|41281898 StAR-related lipid transfer (START) domain containing 13 isoform alpha [Homo sapiens] Length = 1113 Score = 91.7 bits (226), Expect = 2e-18 Identities = 74/242 (30%), Positives = 119/242 (49%), Gaps = 22/242 (9%) Query: 252 LKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILR 311 +KR K +K + +FGVPL ++ + LP + +Q L L LD G+ R Sbjct: 647 MKRMKVPDYK--DKAVFGVPLIVHVQRTGQPLPQS-----IQQALRYLRSNCLDQVGLFR 699 Query: 312 VPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAV 371 G ++R+ L Q E + ++++ D +D++K+F R LP PL T + F Sbjct: 700 KSGVKSRIHALRQMNEN--FPENVNYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLH 757 Query: 372 VPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPN 431 + + +QRLQ + IL+L + NR L+ LL FL VV + N+MT N++ +AP+ Sbjct: 758 IYQYVSKEQRLQAVQAAILLLADENREVLQTLLCFLNDVVNLVEENQMTPMNLAVCLAPS 817 Query: 432 LF-LHQGRPPKLPKGKEKQLAEG------------AAEVVQIMVHYQDLLWTVASFLVAQ 478 LF L+ + P+ +K+ A G AA+ + M+ D L+ V LVAQ Sbjct: 818 LFHLNLLKKESSPRVIQKKYATGKPDQKDLNENLAAAQGLAHMIMECDRLFEVPHELVAQ 877 Query: 479 VR 480 R Sbjct: 878 SR 879 >gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] Length = 1397 Score = 89.7 bits (221), Expect = 7e-18 Identities = 63/177 (35%), Positives = 88/177 (49%), Gaps = 9/177 (5%) Query: 259 KWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILRVPGSQAR 318 K K A R FGV L+ A + +VPL++ A +E RGL+ GI RVPG+ A Sbjct: 800 KNKKAAPRAFGVRLEECQPATE----NQRVPLIVAACCRIVEARGLESTGIYRVPGNNAV 855 Query: 319 VKGLEQKLER---DFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAVVPNI 375 V L+++L R D W ++ N S LLK F RKLP PL T + F I Sbjct: 856 VSSLQEQLNRGPGDINLQDERWQDL--NVISSLLKSFFRKLPEPLFTDDKYNDFIEANRI 913 Query: 376 PNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPNL 432 + ++R++ L LI LP LK L+ L+ + + NKM RN++ V P L Sbjct: 914 EDARERMRTLRKLIRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTL 970 >gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens] Length = 1528 Score = 88.2 bits (217), Expect = 2e-17 Identities = 64/220 (29%), Positives = 106/220 (48%), Gaps = 21/220 (9%) Query: 226 SLQDMRKVPSLALIELTALCD------------ILGLDLKRSKAGKWKAAETRLFGVPLD 273 S+ M + +L++LTAL + + +KR K +K + +FGVPL Sbjct: 1024 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYK--DRSVFGVPLT 1081 Query: 274 SLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAG 333 ++ + LP + +Q + L LD G+ R G ++R++ L Q E Sbjct: 1082 VNVQRTGQPLPQS-----IQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCV 1136 Query: 334 LFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQVLHLLILILP 393 + + D +D+LK++ R LP PL+T + F + QRLQ + I++LP Sbjct: 1137 NYEGQSAY--DVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLP 1194 Query: 394 EPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPNLF 433 + NR L+ LL FL V A + N+MT N++ +AP+LF Sbjct: 1195 DENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLF 1234 >gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens] Length = 1091 Score = 88.2 bits (217), Expect = 2e-17 Identities = 64/220 (29%), Positives = 106/220 (48%), Gaps = 21/220 (9%) Query: 226 SLQDMRKVPSLALIELTALCD------------ILGLDLKRSKAGKWKAAETRLFGVPLD 273 S+ M + +L++LTAL + + +KR K +K + +FGVPL Sbjct: 587 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYK--DRSVFGVPLT 644 Query: 274 SLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAG 333 ++ + LP + +Q + L LD G+ R G ++R++ L Q E Sbjct: 645 VNVQRTGQPLPQS-----IQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCV 699 Query: 334 LFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQVLHLLILILP 393 + + D +D+LK++ R LP PL+T + F + QRLQ + I++LP Sbjct: 700 NYEGQSAY--DVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLP 757 Query: 394 EPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPNLF 433 + NR L+ LL FL V A + N+MT N++ +AP+LF Sbjct: 758 DENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLF 797 >gi|67906814 Rho GTPase activating protein 19 [Homo sapiens] Length = 494 Score = 87.0 bits (214), Expect = 5e-17 Identities = 52/143 (36%), Positives = 78/143 (54%), Gaps = 13/143 (9%) Query: 302 RGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLL 361 + L +EG+ RVPG+ R + L L L S E H ND + LLK F+ +LP PLL Sbjct: 134 KNLRVEGLFRVPGNSVRQQILRDALNNGTDIDLES-GEFHSNDVATLLKMFLGELPEPLL 192 Query: 362 TAEYLPAFAVVP------------NIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRK 409 T ++ A + NIP+ ++++ L LL LILP PNRN LK LL+ L + Sbjct: 193 THKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLKLLLDLLYQ 252 Query: 410 VVAREQHNKMTLRNVSTVMAPNL 432 ++ NKM+ N++ + AP++ Sbjct: 253 TAKKQDKNKMSAYNLALMFAPHV 275 >gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sapiens] Length = 735 Score = 87.0 bits (214), Expect = 5e-17 Identities = 69/216 (31%), Positives = 108/216 (50%), Gaps = 10/216 (4%) Query: 263 AETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGL 322 AE R+FG+PL L+E + P QVPL++Q + +E+RGL + G+ R+ GS A K L Sbjct: 391 AEPRVFGLPLPLLVERER---PPGQVPLIIQKCVGQIERRGLRVVGLYRLCGSAAVKKEL 447 Query: 323 EQKLERDFYAGLFSWDEVHH-NDASDLLKRFIRKLPTPLLTAEYLPAF--AVVPNIPN-L 378 ERD A S D N + +LK ++R+LPTPL+T A+ + PN + Sbjct: 448 RDAFERDSAAVCLSEDLYPDINVITGILKDYLRELPTPLITQPLYKVVLEAMARDPPNRV 507 Query: 379 KQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPNLFLHQGR 438 + L+ LP+ R L LL+ LR V + +N+MT +N++ P + L + Sbjct: 508 PPTTEGTRGLLSCLPDVERATLTLLLDHLRLVSSFHAYNRMTPQNLAVCFGP-VLLPARQ 566 Query: 439 PPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTVASF 474 P P+ + G A V H + L + + S+ Sbjct: 567 APTRPRARSS--GPGLASAVDFKHHIEVLHYLLQSW 600 >gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens] Length = 771 Score = 86.7 bits (213), Expect = 6e-17 Identities = 81/260 (31%), Positives = 113/260 (43%), Gaps = 36/260 (13%) Query: 287 QVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDAS 346 QVP ++ + LEK GL GI RV S+ RV+ L ++ +R L VH D + Sbjct: 206 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVH--DVA 263 Query: 347 DLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEF 406 LLK F+R +P PLLT E AF + + +++L L LLI +LP N + L LL+F Sbjct: 264 ALLKEFLRDMPDPLLTRELYTAF-INTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQF 322 Query: 407 LRKVVAREQH------------NKMTLRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGA 454 L +VAR NKMT N++T+ PNL Q K + AE + Sbjct: 323 L-SIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEES 381 Query: 455 A---EVVQIMVHYQDLLWTVASFLVAQV-----------------RKLNDSSSRRPQLCD 494 VVQ M+ + L+ V L +V RK + SSS + Sbjct: 382 TAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSE 441 Query: 495 AGLKTWLRRMHADRDKAGDG 514 R D +KA G Sbjct: 442 VSFSVGGRHSSTDSNKASSG 461 >gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapiens] Length = 765 Score = 86.7 bits (213), Expect = 6e-17 Identities = 81/260 (31%), Positives = 113/260 (43%), Gaps = 36/260 (13%) Query: 287 QVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDAS 346 QVP ++ + LEK GL GI RV S+ RV+ L ++ +R L VH D + Sbjct: 409 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVH--DVA 466 Query: 347 DLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEF 406 LLK F+R +P PLLT E AF + + +++L L LLI +LP N + L LL+F Sbjct: 467 ALLKEFLRDMPDPLLTRELYTAF-INTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQF 525 Query: 407 LRKVVAREQH------------NKMTLRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGA 454 L +VAR NKMT N++T+ PNL Q K + AE + Sbjct: 526 L-SIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEES 584 Query: 455 A---EVVQIMVHYQDLLWTVASFLVAQV-----------------RKLNDSSSRRPQLCD 494 VVQ M+ + L+ V L +V RK + SSS + Sbjct: 585 TAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSE 644 Query: 495 AGLKTWLRRMHADRDKAGDG 514 R D +KA G Sbjct: 645 VSFSVGGRHSSTDSNKASSG 664 >gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapiens] Length = 974 Score = 86.7 bits (213), Expect = 6e-17 Identities = 81/260 (31%), Positives = 113/260 (43%), Gaps = 36/260 (13%) Query: 287 QVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDAS 346 QVP ++ + LEK GL GI RV S+ RV+ L ++ +R L VH D + Sbjct: 409 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVH--DVA 466 Query: 347 DLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEF 406 LLK F+R +P PLLT E AF + + +++L L LLI +LP N + L LL+F Sbjct: 467 ALLKEFLRDMPDPLLTRELYTAF-INTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQF 525 Query: 407 LRKVVAREQH------------NKMTLRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGA 454 L +VAR NKMT N++T+ PNL Q K + AE + Sbjct: 526 L-SIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEES 584 Query: 455 A---EVVQIMVHYQDLLWTVASFLVAQV-----------------RKLNDSSSRRPQLCD 494 VVQ M+ + L+ V L +V RK + SSS + Sbjct: 585 TAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSE 644 Query: 495 AGLKTWLRRMHADRDKAGDG 514 R D +KA G Sbjct: 645 VSFSVGGRHSSTDSNKASSG 664 >gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo sapiens] Length = 731 Score = 86.3 bits (212), Expect = 8e-17 Identities = 59/188 (31%), Positives = 95/188 (50%), Gaps = 27/188 (14%) Query: 266 RLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQK 325 ++FG L+SL + + +PS L+ ++ ++KRGLD++GI RV G+ A V+ L Sbjct: 519 QVFGCQLESLCQREGDTVPS-----FLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFL 573 Query: 326 LERDFYA---GLF-----------------SWDEVHHNDASDLLKRFIRKLPTPLLTAEY 365 ++R+ G + WD++H + LK F+R+LP PL+ Sbjct: 574 VDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHV--VTGALKLFLRELPQPLVPPLL 631 Query: 366 LPAFAVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVS 425 LP F + +Q L + LI +P+PN + L+ LLE L +V+A N+MT N+ Sbjct: 632 LPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLG 691 Query: 426 TVMAPNLF 433 V P LF Sbjct: 692 IVFGPTLF 699 >gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo sapiens] Length = 547 Score = 86.3 bits (212), Expect = 8e-17 Identities = 59/188 (31%), Positives = 95/188 (50%), Gaps = 27/188 (14%) Query: 266 RLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQK 325 ++FG L+SL + + +PS L+ ++ ++KRGLD++GI RV G+ A V+ L Sbjct: 335 QVFGCQLESLCQREGDTVPS-----FLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFL 389 Query: 326 LERDFYA---GLF-----------------SWDEVHHNDASDLLKRFIRKLPTPLLTAEY 365 ++R+ G + WD++H + LK F+R+LP PL+ Sbjct: 390 VDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHV--VTGALKLFLRELPQPLVPPLL 447 Query: 366 LPAFAVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVS 425 LP F + +Q L + LI +P+PN + L+ LLE L +V+A N+MT N+ Sbjct: 448 LPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLG 507 Query: 426 TVMAPNLF 433 V P LF Sbjct: 508 IVFGPTLF 515 >gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens] Length = 1227 Score = 84.0 bits (206), Expect = 4e-16 Identities = 60/218 (27%), Positives = 107/218 (49%), Gaps = 9/218 (4%) Query: 252 LKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILR 311 LKR + K +T +FGV + + + + ++VP +++ + +E+RG++ GI R Sbjct: 996 LKRMPSRK----QTGVFGVKIAVVTKRER-----SKVPYIVRQCVEEIERRGMEEVGIYR 1046 Query: 312 VPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAV 371 V G ++ L+ + + E+ N + LK + R+LP PL T E+ P FA Sbjct: 1047 VSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAE 1106 Query: 372 VPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPN 431 + + + + L+L LPE N LL+ L++V +E NKM+L N++TV P Sbjct: 1107 GIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPT 1166 Query: 432 LFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLW 469 L + KLP + + + +++M Q LL+ Sbjct: 1167 LLRPSEKESKLPANPSQPITMTDSWSLEVMSQVQVLLY 1204 >gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens] Length = 1271 Score = 84.0 bits (206), Expect = 4e-16 Identities = 60/218 (27%), Positives = 107/218 (49%), Gaps = 9/218 (4%) Query: 252 LKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILR 311 LKR + K +T +FGV + + + + ++VP +++ + +E+RG++ GI R Sbjct: 1040 LKRMPSRK----QTGVFGVKIAVVTKRER-----SKVPYIVRQCVEEIERRGMEEVGIYR 1090 Query: 312 VPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAV 371 V G ++ L+ + + E+ N + LK + R+LP PL T E+ P FA Sbjct: 1091 VSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAE 1150 Query: 372 VPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPN 431 + + + + L+L LPE N LL+ L++V +E NKM+L N++TV P Sbjct: 1151 GIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPT 1210 Query: 432 LFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLW 469 L + KLP + + + +++M Q LL+ Sbjct: 1211 LLRPSEKESKLPANPSQPITMTDSWSLEVMSQVQVLLY 1248 >gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sapiens] Length = 521 Score = 83.6 bits (205), Expect = 5e-16 Identities = 50/180 (27%), Positives = 93/180 (51%), Gaps = 9/180 (5%) Query: 266 RLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQK 325 ++FG L +L E + ++VP +Q + +E RGLD++G+ R+ G+ A ++ L K Sbjct: 325 QVFGCALAALCERER-----SRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYK 379 Query: 326 LERDFYAGLFS--WDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQ 383 ++ D L W++VH + LK F R+LP PL + F + + +R + Sbjct: 380 VDHDERLDLDDGRWEDVHV--ITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSR 437 Query: 384 VLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPNLFLHQGRPPKLP 443 + L+ LP PN + L+ L + L +V+ + N+M++++V+ V P L + +P Sbjct: 438 CVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEETSMP 497 >gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sapiens] Length = 548 Score = 83.6 bits (205), Expect = 5e-16 Identities = 50/180 (27%), Positives = 93/180 (51%), Gaps = 9/180 (5%) Query: 266 RLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQK 325 ++FG L +L E + ++VP +Q + +E RGLD++G+ R+ G+ A ++ L K Sbjct: 352 QVFGCALAALCERER-----SRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYK 406 Query: 326 LERDFYAGLFS--WDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQ 383 ++ D L W++VH + LK F R+LP PL + F + + +R + Sbjct: 407 VDHDERLDLDDGRWEDVHV--ITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSR 464 Query: 384 VLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPNLFLHQGRPPKLP 443 + L+ LP PN + L+ L + L +V+ + N+M++++V+ V P L + +P Sbjct: 465 CVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEETSMP 524 >gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] Length = 1958 Score = 82.8 bits (203), Expect = 9e-16 Identities = 59/175 (33%), Positives = 83/175 (47%), Gaps = 9/175 (5%) Query: 261 KAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILRVPGSQARVK 320 K T FGV LD A + +PL++ +E+RGL+ GI RVPG+ A + Sbjct: 1138 KPTATGTFGVRLDDCPPAH----TNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAIS 1193 Query: 321 GLEQKLER---DFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAVVPNIPN 377 ++++L + D W ++ N S LLK F RKLP PL T + F + Sbjct: 1194 SMQEELNKGMADIDIQDDKWRDL--NVISSLLKSFFRKLPEPLFTNDKYADFIEANRKED 1251 Query: 378 LKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPNL 432 RL+ L LI LPE + LK L L+ V + NKM RN++ V P L Sbjct: 1252 PLDRLKTLKRLIHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTL 1306 >gi|229094128 active breakpoint cluster region-related protein isoform c [Homo sapiens] Length = 813 Score = 82.0 bits (201), Expect = 1e-15 Identities = 65/225 (28%), Positives = 115/225 (51%), Gaps = 28/225 (12%) Query: 250 LDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGI 309 + LKR+ + K +T +FGV + + + + ++VP +++ + +EKRG++ GI Sbjct: 585 MSLKRTPSKK----QTGVFGVKISVVTKRER-----SKVPYIVRQCVEEVEKRGIEEVGI 635 Query: 310 LRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAF 369 R+ G ++ L+ + + L ++ N + LK + R+LP PLLT PAF Sbjct: 636 YRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAF 695 Query: 370 --AVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTV 427 + + P K+ ++HLL LP+PN LLE L++V +E NKM+L N++TV Sbjct: 696 MEGIALSDPAAKENC-MMHLL-RSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATV 753 Query: 428 MAPNLFLHQGRPPKLPKGKEKQLAEGAAEV--------VQIMVHY 464 P L RP ++ + K AA++ VQ++++Y Sbjct: 754 FGPTLL----RPSEV---ESKAHLTSAADIWSHDVMAQVQVLLYY 791 >gi|38679957 active breakpoint cluster region-related protein isoform a [Homo sapiens] Length = 859 Score = 82.0 bits (201), Expect = 1e-15 Identities = 65/225 (28%), Positives = 115/225 (51%), Gaps = 28/225 (12%) Query: 250 LDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGI 309 + LKR+ + K +T +FGV + + + + ++VP +++ + +EKRG++ GI Sbjct: 631 MSLKRTPSKK----QTGVFGVKISVVTKRER-----SKVPYIVRQCVEEVEKRGIEEVGI 681 Query: 310 LRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAF 369 R+ G ++ L+ + + L ++ N + LK + R+LP PLLT PAF Sbjct: 682 YRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAF 741 Query: 370 --AVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTV 427 + + P K+ ++HLL LP+PN LLE L++V +E NKM+L N++TV Sbjct: 742 MEGIALSDPAAKENC-MMHLL-RSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATV 799 Query: 428 MAPNLFLHQGRPPKLPKGKEKQLAEGAAEV--------VQIMVHY 464 P L RP ++ + K AA++ VQ++++Y Sbjct: 800 FGPTLL----RPSEV---ESKAHLTSAADIWSHDVMAQVQVLLYY 837 >gi|38679954 active breakpoint cluster region-related protein isoform b [Homo sapiens] Length = 822 Score = 82.0 bits (201), Expect = 1e-15 Identities = 65/225 (28%), Positives = 115/225 (51%), Gaps = 28/225 (12%) Query: 250 LDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGI 309 + LKR+ + K +T +FGV + + + + ++VP +++ + +EKRG++ GI Sbjct: 594 MSLKRTPSKK----QTGVFGVKISVVTKRER-----SKVPYIVRQCVEEVEKRGIEEVGI 644 Query: 310 LRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAF 369 R+ G ++ L+ + + L ++ N + LK + R+LP PLLT PAF Sbjct: 645 YRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAF 704 Query: 370 --AVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTV 427 + + P K+ ++HLL LP+PN LLE L++V +E NKM+L N++TV Sbjct: 705 MEGIALSDPAAKENC-MMHLL-RSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATV 762 Query: 428 MAPNLFLHQGRPPKLPKGKEKQLAEGAAEV--------VQIMVHY 464 P L RP ++ + K AA++ VQ++++Y Sbjct: 763 FGPTLL----RPSEV---ESKAHLTSAADIWSHDVMAQVQVLLYY 800 >gi|21264337 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [Homo sapiens] Length = 1544 Score = 81.6 bits (200), Expect = 2e-15 Identities = 49/151 (32%), Positives = 78/151 (51%) Query: 288 VPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASD 347 +P+++ A +S + + GL +EG+ R G++AR L + RD + E D +D Sbjct: 919 IPIIVDACISFVTQHGLRLEGVYRKGGARARSLRLLAEFRRDARSVKLRPGEHFVEDVTD 978 Query: 348 LLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFL 407 LKRF R+L P+ +A LP + +P QRL+ +I LP NR L L+ L Sbjct: 979 TLKRFFRELDDPVTSARLLPRWREAAELPQKNQRLEKYKDVIGCLPRVNRRTLATLIGHL 1038 Query: 408 RKVVAREQHNKMTLRNVSTVMAPNLFLHQGR 438 +V N+M RN++ + AP++F GR Sbjct: 1039 YRVQKCAALNQMCTRNLALLFAPSVFQTDGR 1069 >gi|5803145 ralA binding protein 1 [Homo sapiens] Length = 655 Score = 80.9 bits (198), Expect = 3e-15 Identities = 49/166 (29%), Positives = 87/166 (52%), Gaps = 4/166 (2%) Query: 267 LFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQKL 326 +FG+PL +E + ++P V + + +EK G+ EGI RV G +++V L+ Sbjct: 189 IFGIPLADAVERT-MMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAAY 247 Query: 327 ERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQVLH 386 +R+ L ++ N + LLK+++R LP LLT E +P F +++Q Sbjct: 248 DREESTNL---EDYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKVQEFQ 304 Query: 387 LLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPNL 432 L+ LPE N + L+ + V+A+E KM ++N+S V++P + Sbjct: 305 RLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTV 350 >gi|188497642 ARHGAP15 [Homo sapiens] Length = 475 Score = 80.5 bits (197), Expect = 4e-15 Identities = 52/173 (30%), Positives = 86/173 (49%), Gaps = 17/173 (9%) Query: 266 RLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGL--- 322 ++FG L + E ++ VP ++ + +EKRGLD++GI RV G+ A ++ L Sbjct: 277 QIFGSHLHKVCERENST-----VPWFVKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFI 331 Query: 323 ---EQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLK 379 E+KL D W+++H + LK F R+LP PL + F + Sbjct: 332 VNQEEKLNLDDS----QWEDIHV--VTGALKMFFRELPEPLFPYSFFEQFVEAIKKQDNN 385 Query: 380 QRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPNL 432 R++ + L+ LP PNR+ +K L L K+VA+ N M+ +++ V P L Sbjct: 386 TRIEAVKSLVQKLPPPNRDTMKVLFGHLTKIVAKASKNLMSTQSLGIVFGPTL 438 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.134 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,678,288 Number of Sequences: 37866 Number of extensions: 1135387 Number of successful extensions: 3850 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 98 Number of HSP's successfully gapped in prelim test: 36 Number of HSP's that attempted gapping in prelim test: 3624 Number of HSP's gapped (non-prelim): 161 length of query: 622 length of database: 18,247,518 effective HSP length: 108 effective length of query: 514 effective length of database: 14,157,990 effective search space: 7277206860 effective search space used: 7277206860 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.