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Search of human proteins with 118600973
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|118600973 RNA binding motif protein, X-linked 2 [Homo
sapiens]
(322 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|118600973 RNA binding motif protein, X-linked 2 [Homo sapiens] 652 0.0
gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi... 90 3e-18
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 80 2e-15
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 80 2e-15
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 76 4e-14
gi|14149675 cleavage stimulation factor, 3' pre-RNA, subunit 2, ... 76 5e-14
gi|4557493 cleavage stimulation factor subunit 2 [Homo sapiens] 75 6e-14
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 74 1e-13
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 72 5e-13
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 71 1e-12
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 70 3e-12
gi|51243065 zinc finger CCHC-type and RNA binding motif 1 [Homo ... 70 3e-12
gi|52426743 cisplatin resistance-associated overexpressed protei... 69 4e-12
gi|19923485 cisplatin resistance-associated overexpressed protei... 69 4e-12
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 69 6e-12
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 69 6e-12
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 69 6e-12
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 69 6e-12
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 69 7e-12
gi|20911035 peptidylprolyl isomerase-like 4 [Homo sapiens] 68 1e-11
gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens] 67 3e-11
gi|7661936 scaffold attachment factor B2 [Homo sapiens] 67 3e-11
gi|187960109 RNA binding motif protein 28 [Homo sapiens] 64 2e-10
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 63 3e-10
gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens] 62 5e-10
gi|116734696 RNA binding motif protein 23 isoform 1 [Homo sapiens] 62 5e-10
gi|116734694 RNA binding motif protein 23 isoform 2 [Homo sapiens] 62 5e-10
gi|9558733 transformer-2 alpha [Homo sapiens] 62 9e-10
gi|56699409 RNA binding motif protein, X-linked [Homo sapiens] 62 9e-10
gi|40068059 CBF1 interacting corepressor [Homo sapiens] 61 1e-09
>gi|118600973 RNA binding motif protein, X-linked 2 [Homo sapiens]
Length = 322
Score = 652 bits (1683), Expect = 0.0
Identities = 322/322 (100%), Positives = 322/322 (100%)
Query: 1 MNPLTKVKLINELNEREVQLGVADKVSWHSEYKDSAWIFLGGLPYELTEGDIICVFSQYG 60
MNPLTKVKLINELNEREVQLGVADKVSWHSEYKDSAWIFLGGLPYELTEGDIICVFSQYG
Sbjct: 1 MNPLTKVKLINELNEREVQLGVADKVSWHSEYKDSAWIFLGGLPYELTEGDIICVFSQYG 60
Query: 61 EIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNFNGIKIKGRTIRVDHVSNYRAPKD 120
EIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNFNGIKIKGRTIRVDHVSNYRAPKD
Sbjct: 61 EIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNFNGIKIKGRTIRVDHVSNYRAPKD 120
Query: 121 SEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQ 180
SEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQ
Sbjct: 121 SEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQ 180
Query: 181 AEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLER 240
AEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLER
Sbjct: 181 AEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLER 240
Query: 241 ELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSH 300
ELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSH
Sbjct: 241 ELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSH 300
Query: 301 RHKRARRSRERESSNPSDRWRH 322
RHKRARRSRERESSNPSDRWRH
Sbjct: 301 RHKRARRSRERESSNPSDRWRH 322
>gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo
sapiens]
Length = 437
Score = 89.7 bits (221), Expect = 3e-18
Identities = 77/302 (25%), Positives = 127/302 (42%), Gaps = 47/302 (15%)
Query: 38 IFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNF 97
+F+ + Y+ TE + F YG I I++V K++GK +G+ F+ YE +R A +
Sbjct: 105 LFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHA 164
Query: 98 NGIKIKGRTIRVD-----HVSNYRAPKDSEEI-----------------DDVTRQLQEKG 135
+G KI GR + VD V +R + + DD +R + G
Sbjct: 165 DGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPG 224
Query: 136 CGARTPSP-SLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTV 194
PSP + D + ++ + +++K+++++ DR ++ RR
Sbjct: 225 -----PSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRE 279
Query: 195 KEKD-DTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHE--- 250
+ KD D K+ SS++ ERA++ R+ + GG + E + P +
Sbjct: 280 RSKDKDRDRKRRSSRSRERARRERERKEE-------LRGGGGDMAEPSEAGDAPPDDGPP 332
Query: 251 -HKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSHRHKRARRSR 309
+ EEK R RDR R + RSE R R R RD+ HKR R
Sbjct: 333 GELGPDGPDGPEEKGRDRDRERRR-------SHRSERERRRDRDRDRDRDREHKRGERGS 385
Query: 310 ER 311
ER
Sbjct: 386 ER 387
Score = 39.7 bits (91), Expect = 0.004
Identities = 33/89 (37%), Positives = 39/89 (43%), Gaps = 11/89 (12%)
Query: 234 GAEDLERELKKEKPKH-EHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSR 292
G +D R ++ P H+ R RE + R R R R + RS R R R
Sbjct: 212 GRDDTSRYDERPGPSPLPHRDRDRD--RERERRERSRERDKERE----RRRSRSRDRRRR 265
Query: 293 SRSRDKSHRHKRARRSRERESSNPSDRWR 321
SRSRDK R RRSRER DR R
Sbjct: 266 SRSRDKEER----RRSRERSKDKDRDRKR 290
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 80.1 bits (196), Expect = 2e-15
Identities = 67/302 (22%), Positives = 129/302 (42%), Gaps = 28/302 (9%)
Query: 38 IFLGGLPYELTEGD-IICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDN 96
+++G L + T D ++ F Q GE+ + + D+ + F F+ + DQ S A+
Sbjct: 184 VYVGNLNSQTTTADQLLEFFKQVGEVKFVRMAGDET--QPTRFAFVEFADQNSVPRALA- 240
Query: 97 FNGIKIKGRTIRVDHVSN----------YRAPKDSEEIDDVTRQLQEKGCGARTPSPSLS 146
FNG+ R ++++H +N A K+ EE+ R+ Q A P S
Sbjct: 241 FNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKS 300
Query: 147 ES-----------SEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVK 195
S+ +K H + K+ + K + R Q ++ S SP +K K
Sbjct: 301 NERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 360
Query: 196 EKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSS 255
++ + S +R E + ++ K + + ERE +KE+ K++ +
Sbjct: 361 SRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKE 420
Query: 256 RREARE-EKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSHRHKRARRSRERESS 314
R + RE +K + R+R R + H + E + + R +D+S + +R ++++S
Sbjct: 421 REKDREKDKEKDREREREKE-HEKDRDKEKEKEQDKEKEREKDRS-KEIDEKRKKDKKSR 478
Query: 315 NP 316
P
Sbjct: 479 TP 480
Score = 60.1 bits (144), Expect = 3e-09
Identities = 49/192 (25%), Positives = 84/192 (43%), Gaps = 18/192 (9%)
Query: 139 RTPSPSLSESSEDEKPT------KKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRK 192
R S S S S + K T K+ K+K +K++++EKE+ + + + R K
Sbjct: 364 RRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREK 423
Query: 193 TVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEK-----P 247
++ + ++ K E+ + E + Q K R +++++ + KK+K P
Sbjct: 424 DREKDKEKDREREREKEHEKDRDKEKEKEQDKEKERE--KDRSKEIDEKRKKDKKSRTPP 481
Query: 248 KHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRS-----RDKSHRH 302
+ + S R + E+ R R R S +S R RS RSR+ R+K H
Sbjct: 482 RSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDH 541
Query: 303 KRARRSRERESS 314
RR RER +S
Sbjct: 542 ISERRERERSTS 553
Score = 55.1 bits (131), Expect = 8e-08
Identities = 52/202 (25%), Positives = 88/202 (43%), Gaps = 19/202 (9%)
Query: 119 KDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADRE 178
KD+ E +++EK E ++ K K++++ ++K KEK++ +RE
Sbjct: 378 KDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDR-ERE 436
Query: 179 VQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRT-AYSGGAED 237
+ E ++ ++K+ K S + E+ +K + KSRT S A
Sbjct: 437 REKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK--------KSRTPPRSYNASR 488
Query: 238 LERELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRD 297
R +E+ + +SSS R R KT R RS + RS + + R + RD
Sbjct: 489 RSRSSSRERRRRRSRSSS-RSPRTSKTIKRKSSRSP-------SPRSRNKKDKKREKERD 540
Query: 298 K-SHRHKRARRSRERESSNPSD 318
S R +R R + R+SSN D
Sbjct: 541 HISERRERERSTSMRKSSNDRD 562
Score = 52.0 bits (123), Expect = 7e-07
Identities = 55/226 (24%), Positives = 89/226 (39%), Gaps = 22/226 (9%)
Query: 95 DNFNGIKIKGRTIRVDHVSNYRAPKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKP 154
D IK K R D K+ E+ +E+G + +D++
Sbjct: 379 DTREKIKEKERVKEKDREKEREREKEREKE-------KERGKNKDRDKEREKDREKDKEK 431
Query: 155 TKKHKKDKKEKKKKKKEKE-KADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERA 213
++ +++K+ +K + KEKE + D+E + E+ S K K+K P + S N+ R
Sbjct: 432 DREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPR--SYNASRR 489
Query: 214 QKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRSS 273
+S RE R S + R K K K S R +++K R ++R
Sbjct: 490 SRSSSRE------RRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERD--- 540
Query: 274 DAHSSWYNGRSEGRSYRSRSRSRD-KSHRHKRARRSRERESSNPSD 318
H S R S R S RD K K + +E+E + D
Sbjct: 541 --HISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPD 584
Score = 34.7 bits (78), Expect = 0.12
Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 7/83 (8%)
Query: 246 KPKHEHKSSSRREAREEKTRIRDR----GRSSDAHSSWYNGRSEGRSY---RSRSRSRDK 298
KP ++ +E E R+R+ + + S N R GRS RS+SRS K
Sbjct: 262 KPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSK 321
Query: 299 SHRHKRARRSRERESSNPSDRWR 321
SH ++ +S+ R S+ R R
Sbjct: 322 SHSRRKRSQSKHRSRSHNRSRSR 344
Score = 32.3 bits (72), Expect = 0.58
Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 4/88 (4%)
Query: 235 AEDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSR 294
A++LE +K+ + S++ E K+ R GRS S RS +S+ R R
Sbjct: 272 AKELEEVMKRVREAQSFISAAI-EPESGKSNERKGGRSRSHTRS--KSRSSSKSHSRRKR 328
Query: 295 SRDKSHRHKRARRSRERESSNPSDRWRH 322
S+ K HR + RSR R+ + H
Sbjct: 329 SQSK-HRSRSHNRSRSRQKDRRRSKSPH 355
Score = 30.0 bits (66), Expect = 2.9
Identities = 30/133 (22%), Positives = 65/133 (48%), Gaps = 23/133 (17%)
Query: 103 KGRTIRVDHVSNYRAPKDSEEIDDVTRQLQEKGCGARTPSPSLS---ESSEDEKPTKKHK 159
K RT + ++ R+ S E R+ + +R+P S + +SS P ++K
Sbjct: 476 KSRTPPRSYNASRRSRSSSRE-----RRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 530
Query: 160 K-DKKEKKK----KKKEKEKA----------DREVQAEQPSSSSPRRKTVKEKDDTGPKK 204
K K+EK++ +++E+E++ D + + E+ S+S ++ KE D + K+
Sbjct: 531 KDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 590
Query: 205 HSSKNSERAQKSE 217
K++ R ++++
Sbjct: 591 VDDKDAPRTEENK 603
Score = 29.3 bits (64), Expect = 4.9
Identities = 27/120 (22%), Positives = 46/120 (38%), Gaps = 24/120 (20%)
Query: 113 SNYRAPKDSEEIDDVTRQLQEKGCGARTPSPS---------------LSESSEDEKPTKK 157
S+ R+P+ S+ I K +R+PSP +SE E E+ T
Sbjct: 504 SSSRSPRTSKTI---------KRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSM 554
Query: 158 HKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSE 217
K K+K EK + + S K V +KD +++ +++ Q +E
Sbjct: 555 RKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNE 614
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 80.1 bits (196), Expect = 2e-15
Identities = 67/302 (22%), Positives = 129/302 (42%), Gaps = 28/302 (9%)
Query: 38 IFLGGLPYELTEGD-IICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDN 96
+++G L + T D ++ F Q GE+ + + D+ + F F+ + DQ S A+
Sbjct: 68 VYVGNLNSQTTTADQLLEFFKQVGEVKFVRMAGDET--QPTRFAFVEFADQNSVPRALA- 124
Query: 97 FNGIKIKGRTIRVDHVSN----------YRAPKDSEEIDDVTRQLQEKGCGARTPSPSLS 146
FNG+ R ++++H +N A K+ EE+ R+ Q A P S
Sbjct: 125 FNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKS 184
Query: 147 ES-----------SEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVK 195
S+ +K H + K+ + K + R Q ++ S SP +K K
Sbjct: 185 NERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 244
Query: 196 EKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSS 255
++ + S +R E + ++ K + + ERE +KE+ K++ +
Sbjct: 245 SRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKE 304
Query: 256 RREARE-EKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSHRHKRARRSRERESS 314
R + RE +K + R+R R + H + E + + R +D+S + +R ++++S
Sbjct: 305 REKDREKDKEKDREREREKE-HEKDRDKEKEKEQDKEKEREKDRS-KEIDEKRKKDKKSR 362
Query: 315 NP 316
P
Sbjct: 363 TP 364
Score = 60.1 bits (144), Expect = 3e-09
Identities = 49/192 (25%), Positives = 84/192 (43%), Gaps = 18/192 (9%)
Query: 139 RTPSPSLSESSEDEKPT------KKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRK 192
R S S S S + K T K+ K+K +K++++EKE+ + + + R K
Sbjct: 248 RRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREK 307
Query: 193 TVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEK-----P 247
++ + ++ K E+ + E + Q K R +++++ + KK+K P
Sbjct: 308 DREKDKEKDREREREKEHEKDRDKEKEKEQDKEKERE--KDRSKEIDEKRKKDKKSRTPP 365
Query: 248 KHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRS-----RDKSHRH 302
+ + S R + E+ R R R S +S R RS RSR+ R+K H
Sbjct: 366 RSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDH 425
Query: 303 KRARRSRERESS 314
RR RER +S
Sbjct: 426 ISERRERERSTS 437
Score = 55.1 bits (131), Expect = 8e-08
Identities = 52/202 (25%), Positives = 88/202 (43%), Gaps = 19/202 (9%)
Query: 119 KDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADRE 178
KD+ E +++EK E ++ K K++++ ++K KEK++ +RE
Sbjct: 262 KDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDR-ERE 320
Query: 179 VQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRT-AYSGGAED 237
+ E ++ ++K+ K S + E+ +K + KSRT S A
Sbjct: 321 REKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK--------KSRTPPRSYNASR 372
Query: 238 LERELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRD 297
R +E+ + +SSS R R KT R RS + RS + + R + RD
Sbjct: 373 RSRSSSRERRRRRSRSSS-RSPRTSKTIKRKSSRSP-------SPRSRNKKDKKREKERD 424
Query: 298 K-SHRHKRARRSRERESSNPSD 318
S R +R R + R+SSN D
Sbjct: 425 HISERRERERSTSMRKSSNDRD 446
Score = 52.0 bits (123), Expect = 7e-07
Identities = 55/226 (24%), Positives = 89/226 (39%), Gaps = 22/226 (9%)
Query: 95 DNFNGIKIKGRTIRVDHVSNYRAPKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKP 154
D IK K R D K+ E+ +E+G + +D++
Sbjct: 263 DTREKIKEKERVKEKDREKEREREKEREKE-------KERGKNKDRDKEREKDREKDKEK 315
Query: 155 TKKHKKDKKEKKKKKKEKE-KADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERA 213
++ +++K+ +K + KEKE + D+E + E+ S K K+K P + S N+ R
Sbjct: 316 DREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPR--SYNASRR 373
Query: 214 QKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRSS 273
+S RE R S + R K K K S R +++K R ++R
Sbjct: 374 SRSSSRE------RRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERD--- 424
Query: 274 DAHSSWYNGRSEGRSYRSRSRSRD-KSHRHKRARRSRERESSNPSD 318
H S R S R S RD K K + +E+E + D
Sbjct: 425 --HISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPD 468
Score = 34.7 bits (78), Expect = 0.12
Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 7/83 (8%)
Query: 246 KPKHEHKSSSRREAREEKTRIRDR----GRSSDAHSSWYNGRSEGRSY---RSRSRSRDK 298
KP ++ +E E R+R+ + + S N R GRS RS+SRS K
Sbjct: 146 KPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSK 205
Query: 299 SHRHKRARRSRERESSNPSDRWR 321
SH ++ +S+ R S+ R R
Sbjct: 206 SHSRRKRSQSKHRSRSHNRSRSR 228
Score = 32.3 bits (72), Expect = 0.58
Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 4/88 (4%)
Query: 235 AEDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSR 294
A++LE +K+ + S++ E K+ R GRS S RS +S+ R R
Sbjct: 156 AKELEEVMKRVREAQSFISAAI-EPESGKSNERKGGRSRSHTRS--KSRSSSKSHSRRKR 212
Query: 295 SRDKSHRHKRARRSRERESSNPSDRWRH 322
S+ K HR + RSR R+ + H
Sbjct: 213 SQSK-HRSRSHNRSRSRQKDRRRSKSPH 239
Score = 30.0 bits (66), Expect = 2.9
Identities = 30/133 (22%), Positives = 65/133 (48%), Gaps = 23/133 (17%)
Query: 103 KGRTIRVDHVSNYRAPKDSEEIDDVTRQLQEKGCGARTPSPSLS---ESSEDEKPTKKHK 159
K RT + ++ R+ S E R+ + +R+P S + +SS P ++K
Sbjct: 360 KSRTPPRSYNASRRSRSSSRE-----RRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 414
Query: 160 K-DKKEKKK----KKKEKEKA----------DREVQAEQPSSSSPRRKTVKEKDDTGPKK 204
K K+EK++ +++E+E++ D + + E+ S+S ++ KE D + K+
Sbjct: 415 KDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 474
Query: 205 HSSKNSERAQKSE 217
K++ R ++++
Sbjct: 475 VDDKDAPRTEENK 487
Score = 29.3 bits (64), Expect = 4.9
Identities = 27/120 (22%), Positives = 46/120 (38%), Gaps = 24/120 (20%)
Query: 113 SNYRAPKDSEEIDDVTRQLQEKGCGARTPSPS---------------LSESSEDEKPTKK 157
S+ R+P+ S+ I K +R+PSP +SE E E+ T
Sbjct: 388 SSSRSPRTSKTI---------KRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSM 438
Query: 158 HKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSE 217
K K+K EK + + S K V +KD +++ +++ Q +E
Sbjct: 439 RKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNE 498
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 76.3 bits (186), Expect = 4e-14
Identities = 60/192 (31%), Positives = 88/192 (45%), Gaps = 18/192 (9%)
Query: 128 TRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKE-KADREVQAEQPSS 186
+R+ + K S S S E + K K KK K ++ +KE +D+ + S
Sbjct: 47 SRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSE 106
Query: 187 SSPRRKTVKEKDDTGPKKHS-SKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKE 245
+ R KE+ + + HS S++ ER +S RE +K +SR+ RE KK
Sbjct: 107 NGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKK-SRSRS----------RERKKS 155
Query: 246 KPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSHRHKRA 305
+ + + SR +RE K RIR R RS H RS R+RSRSRD+ R ++
Sbjct: 156 RSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRS-----RTRSRSRDRKKRIEKP 210
Query: 306 RRSRERESSNPS 317
RR S PS
Sbjct: 211 RRFSRSLSRTPS 222
Score = 70.1 bits (170), Expect = 3e-12
Identities = 58/200 (29%), Positives = 89/200 (44%), Gaps = 13/200 (6%)
Query: 117 APKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKAD 176
AP+ + D ++ E R S S + +K K D + +K + + + K
Sbjct: 12 APEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRE-RKRKSDNEGRKHRSRSRSKEG 70
Query: 177 REVQAEQPSSSSPRRKTVKEKDDTGPKKHSS-KNSERAQKSEPREGQKLPKSRTAYSGGA 235
R + E SS + K+ + D K+HSS K ER SE E + K R + G +
Sbjct: 71 R--RHESKDKSSKKHKSEEHND----KEHSSDKGRERLNSSENGEDRHKRKERKSSRGRS 124
Query: 236 EDLERELKKEKPKHEHKSSSRREAREE-KTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSR 294
R ++ +H +S R+++R + R + R RS + S R R RSRSR
Sbjct: 125 HSRSRSRER---RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSR 181
Query: 295 SRDKSHRHKRARRSRERESS 314
SR + HRH+ RSR R S
Sbjct: 182 SRSR-HRHRTRSRSRTRSRS 200
Score = 60.8 bits (146), Expect = 2e-09
Identities = 45/154 (29%), Positives = 67/154 (43%), Gaps = 12/154 (7%)
Query: 175 ADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGG 234
+D E P +SP R KE+ + +SK+ +S RE + R + + G
Sbjct: 4 SDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRE-----RKRKSDNEG 58
Query: 235 AEDLERELKKEKPKHEHKSSS----RREAREEKTRIRDRGR---SSDAHSSWYNGRSEGR 287
+ R KE +HE K S + E +K D+GR +S + + R E +
Sbjct: 59 RKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERK 118
Query: 288 SYRSRSRSRDKSHRHKRARRSRERESSNPSDRWR 321
S R RS SR +S + RSRER+ S R R
Sbjct: 119 SSRGRSHSRSRSRERRHRSRSRERKKSRSRSRER 152
Score = 57.4 bits (137), Expect = 2e-08
Identities = 52/198 (26%), Positives = 79/198 (39%), Gaps = 33/198 (16%)
Query: 133 EKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRK 192
EK R SE S + +K H + + + ++ K K+D E + + S S +
Sbjct: 14 EKTSPDRDKKKEQSEVSVSPRASKHHYS--RSRSRSRERKRKSDNEGRKHRSRSRSKEGR 71
Query: 193 TVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHK 252
+ KD + K S +++++ S+ K R + +R +KE+ +
Sbjct: 72 RHESKDKSSKKHKSEEHNDKEHSSD--------KGRERLNSSENGEDRHKRKERKSSRGR 123
Query: 253 SSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSHRHKRAR-----R 307
S SR +RE + R R R R RSRSR R KS R R R
Sbjct: 124 SHSRSRSRERRHRSRSRERKKS---------------RSRSRERKKSRSRSRERKKSRSR 168
Query: 308 SRERE---SSNPSDRWRH 322
SRER+ S R RH
Sbjct: 169 SRERKRRIRSRSRSRSRH 186
>gi|14149675 cleavage stimulation factor, 3' pre-RNA, subunit 2,
64kDa, tau variant [Homo sapiens]
Length = 616
Score = 75.9 bits (185), Expect = 5e-14
Identities = 36/87 (41%), Positives = 56/87 (64%), Gaps = 3/87 (3%)
Query: 38 IFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNF 97
+F+G +PYE TE + +FS+ G +V+ LV D++TGK KG+ F Y+DQ + + A+ N
Sbjct: 18 VFVGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNL 77
Query: 98 NGIKIKGRTIRVDHVSNYRAPKDSEEI 124
NG + GR +RVD N + K+ EE+
Sbjct: 78 NGREFSGRALRVD---NAASEKNKEEL 101
>gi|4557493 cleavage stimulation factor subunit 2 [Homo sapiens]
Length = 577
Score = 75.5 bits (184), Expect = 6e-14
Identities = 36/87 (41%), Positives = 56/87 (64%), Gaps = 3/87 (3%)
Query: 38 IFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNF 97
+F+G +PYE TE + +FS+ G +V+ LV D++TGK KG+ F Y+DQ + + A+ N
Sbjct: 18 VFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNL 77
Query: 98 NGIKIKGRTIRVDHVSNYRAPKDSEEI 124
NG + GR +RVD N + K+ EE+
Sbjct: 78 NGREFSGRALRVD---NAASEKNKEEL 101
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 74.3 bits (181), Expect = 1e-13
Identities = 54/213 (25%), Positives = 92/213 (43%), Gaps = 3/213 (1%)
Query: 109 VDHVSNYRAPKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKK 168
V +S+ A K + E+ V+ K C R +++ ++ K+ K+E+ KK
Sbjct: 2 VKAISSRAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKK 61
Query: 169 KKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSR 228
+K+K K RE E+ R K KE+ + +K + +R +K R +K K R
Sbjct: 62 EKKKRK-KRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKER 120
Query: 229 TAYS-GGAEDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGR 287
+ ER+ KK + K K R + R ++ R R + + + R E +
Sbjct: 121 KERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERK 180
Query: 288 SYRSRSRSRD-KSHRHKRARRSRERESSNPSDR 319
R R R+ K R K R+ +ER+ +DR
Sbjct: 181 KERERKERRERKKERKKERRKKKERKKDRKTDR 213
Score = 53.1 bits (126), Expect = 3e-07
Identities = 27/138 (19%), Positives = 65/138 (47%)
Query: 129 RQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSS 188
R+ Q K + E + E+ + ++ KK+K++K++E+E R + +
Sbjct: 82 REKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKK 141
Query: 189 PRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPK 248
RRK K + + G ++ K ++ ++ + RE + + + + ++E KKE+ K
Sbjct: 142 KRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRK 201
Query: 249 HEHKSSSRREAREEKTRI 266
+ + R+ R+ +++
Sbjct: 202 KKERKKDRKTDRQTDSQV 219
Score = 38.5 bits (88), Expect = 0.008
Identities = 24/115 (20%), Positives = 50/115 (43%)
Query: 119 KDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADRE 178
K+ E + R+ + K + E K +K KK KKE+++KK+E+ + +R+
Sbjct: 121 KERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERK 180
Query: 179 VQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSG 233
+ E+ +++ KE+ +K K + R ++ +R +G
Sbjct: 181 KERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRVTVTG 235
Score = 30.4 bits (67), Expect = 2.2
Identities = 20/102 (19%), Positives = 45/102 (44%), Gaps = 3/102 (2%)
Query: 101 KIKGRTIRVDHVSNYRAPKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKK 160
K +GR R +++++ + R+ + K + + K K+ K+
Sbjct: 107 KQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKE 166
Query: 161 D---KKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDD 199
+ K+E+ +K+++KE+ +E + + RRK + K D
Sbjct: 167 EREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKD 208
>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
sapiens]
Length = 375
Score = 72.4 bits (176), Expect = 5e-13
Identities = 54/173 (31%), Positives = 74/173 (42%), Gaps = 17/173 (9%)
Query: 145 LSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKK 204
L + E K KK K E+ K+ RE + + R K + K G
Sbjct: 8 LKQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRE-RLNSSENGEDRHKRKERKSSRGRSH 66
Query: 205 HSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKT 264
S++ ER +S RE +K +SR+ RE KK + + + SR +RE K
Sbjct: 67 SRSRSRERRHRSRSRERKK-SRSRS----------RERKKSRSRSRERKKSRSRSRERKR 115
Query: 265 RIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSHRHKRARRSRERESSNPS 317
RIR R RS H RS R+RSRSRD+ R ++ RR S PS
Sbjct: 116 RIRSRSRSRSRHRHRTRSRS-----RTRSRSRDRKKRIEKPRRFSRSLSRTPS 163
Score = 54.7 bits (130), Expect = 1e-07
Identities = 39/127 (30%), Positives = 52/127 (40%), Gaps = 12/127 (9%)
Query: 196 EKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSS 255
E D KKH S+ + S + ++L S +R +KE+ +S S
Sbjct: 15 ESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGE-------DRHKRKERKSSRGRSHS 67
Query: 256 RREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSHRHKRARRSRERESSN 315
R +RE + R R R R S E + RSRSR R KS R R+ R R S
Sbjct: 68 RSRSRERRHRSRSRERKKSRSRS-----RERKKSRSRSRERKKSRSRSRERKRRIRSRSR 122
Query: 316 PSDRWRH 322
R RH
Sbjct: 123 SRSRHRH 129
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 71.2 bits (173), Expect = 1e-12
Identities = 79/334 (23%), Positives = 145/334 (43%), Gaps = 57/334 (17%)
Query: 38 IFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNF 97
+F+G + + ++ I + ++ G +++ V+ +GK + F F Y++ ST+ A+
Sbjct: 89 VFVGNISEKASDMLIRQLLAKCGLVLSWKRVQGA-SGKLQAFGFCEYKEPESTLRALRLL 147
Query: 98 NGIKI--KGRTIRVD-----HVSNYRAPK---------------DSEEIDDVTRQLQEKG 135
+ ++I K ++VD + ++A K D E +D+ T++ +
Sbjct: 148 HDLQIGEKKLLVKVDAKTKAQLDEWKAKKKASNGNARPETVTNDDEEALDEETKRRDQMI 207
Query: 136 CGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKK------------------------- 170
GA SSE P+++ ++KKK+KK
Sbjct: 208 KGA-IEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINA 266
Query: 171 -EKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRT 229
E E+ R++ + + S K ++E+ K+ ER ++ RE ++ + R
Sbjct: 267 IEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERE 326
Query: 230 AYSGGAEDLERELKKEKPKHEHKSSSR-REAREEKTRIRDRGRSSDAHSSWYNGRSEGRS 288
+ ERE +KEK + + R R+ +E+ R RDR R D + R++ RS
Sbjct: 327 R----EREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRS 382
Query: 289 YRSRSRSRDKSHRHKRAR-RSRERESSNPSDRWR 321
RSR +SRD+ +R R R RERE +R R
Sbjct: 383 -RSREKSRDRERERERERERERERERERERERER 415
Score = 59.3 bits (142), Expect = 4e-09
Identities = 47/177 (26%), Positives = 78/177 (44%), Gaps = 23/177 (12%)
Query: 147 ESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHS 206
E ED++ + K KK E+EK +E E+ RR+ +E++ ++
Sbjct: 268 EMEEDKRDLISREISKFRDTHKKLEEEKGKKE--KERQEIEKERRERERERERERERRER 325
Query: 207 SKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSR-REAREEKTR 265
+ ER ++ E ++ ERE ++E+ + ++ R R+ E+ R
Sbjct: 326 ERERERERERE------------------KEKERERERERDRDRDRTKERDRDRDRERDR 367
Query: 266 IRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSHRHKRAR-RSRERESSNPSDRWR 321
RDR RSSD + R + R R R R R++ +R R R RERE +R R
Sbjct: 368 DRDRERSSDRNKDRSRSREKSRD-RERERERERERERERERERERERERERERERER 423
Score = 55.8 bits (133), Expect = 5e-08
Identities = 38/202 (18%), Positives = 92/202 (45%), Gaps = 22/202 (10%)
Query: 120 DSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREV 179
+ ++ D ++R++ + + + ++ + +K +++++ ++++++E+ + +RE
Sbjct: 270 EEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERER 329
Query: 180 QAEQPSSSSPRRKTVKEKD---DTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAE 236
+ E+ R+ +E+D D ++ ++ ER + + K R+ +
Sbjct: 330 EREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSR 389
Query: 237 DLERELKKEKPKHEHKSSSR-REAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRS 295
D ERE ++E+ + + R RE E+ R R+R R D + R R
Sbjct: 390 DREREREREREREREREREREREREREREREREREREKD---------------KKRDRE 434
Query: 296 RDKS---HRHKRARRSRERESS 314
D+ R K R+ RE+E++
Sbjct: 435 EDEEDAYERRKLERKLREKEAA 456
Score = 55.8 bits (133), Expect = 5e-08
Identities = 38/210 (18%), Positives = 93/210 (44%), Gaps = 8/210 (3%)
Query: 119 KDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADRE 178
++ + D ++L+E+ + + + + ++ +++++E++++++ + + ++E
Sbjct: 279 REISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKE 338
Query: 179 VQAEQPSSSSPRRKTVKEKD-DTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAED 237
+ E+ R KE+D D ++ ++ ER+ + KSR +
Sbjct: 339 KERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERE 398
Query: 238 LERELKKEKPKHEHKSSSR-REAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSR---- 292
ERE ++E+ + + R RE E+ + + R R D + Y R R R +
Sbjct: 399 REREREREREREREREREREREREREREKDKKRDREEDEEDA-YERRKLERKLREKEAAY 457
Query: 293 -SRSRDKSHRHKRARRSRERESSNPSDRWR 321
R ++ R ++ R E+E+ +R R
Sbjct: 458 QERLKNWEIRERKKTREYEKEAEREEERRR 487
Score = 53.5 bits (127), Expect = 2e-07
Identities = 47/200 (23%), Positives = 93/200 (46%), Gaps = 30/200 (15%)
Query: 122 EEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQA 181
E+I+ + + ++ +R S + E+ K +K+++E +K+++E+E+ +RE +
Sbjct: 262 EDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERER-ERERER 320
Query: 182 EQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERE 241
E RR+ +E++ ++ K ER ++ E + K R D +R+
Sbjct: 321 E-------RRERERERE---REREREKEKERERERERDRDRDRTKERDRDRDRERDRDRD 370
Query: 242 LKKEKPKHEHKSSSRREARE-EKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSH 300
++ +++ +S SR ++R+ E+ R R+R R R R R R++
Sbjct: 371 RERSSDRNKDRSRSREKSRDRERERERERERE-----------------RERERERERER 413
Query: 301 RHKRAR-RSRERESSNPSDR 319
+R R R RERE DR
Sbjct: 414 EREREREREREREKDKKRDR 433
Score = 42.7 bits (99), Expect = 4e-04
Identities = 40/208 (19%), Positives = 85/208 (40%), Gaps = 7/208 (3%)
Query: 119 KDSEEIDDVTRQLQEKGCGARTPSPSLSESS-EDEKPTKKHKKDKKEKKKKKKEKEKADR 177
K+ +EI+ R+ + + R E E E+ +K ++ ++E+ + + ++ DR
Sbjct: 300 KERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDR 359
Query: 178 EVQAEQPSSSSPRRKTVKEKDDTGPKKHS---SKNSERAQKSEPREGQKLPKSRTAYSGG 234
+ E+ R + + KD + ++ S + ER ++ E ++ + R
Sbjct: 360 DRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERER 419
Query: 235 AEDLERELKKEKPKHEHKSSS-RREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRS 293
+ ERE K++ + E + + R E K R ++ + R + R Y +
Sbjct: 420 EREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEA 479
Query: 294 RSRDKSHRH--KRARRSRERESSNPSDR 319
++ R K A+R +E DR
Sbjct: 480 EREEERRREMAKEAKRLKEFLEDYDDDR 507
Score = 32.7 bits (73), Expect = 0.44
Identities = 16/83 (19%), Positives = 42/83 (50%), Gaps = 1/83 (1%)
Query: 147 ESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHS 206
E DE+ K+ K++ +E +++ + D + + ++ + RR+ + K + ++
Sbjct: 528 EMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEE 587
Query: 207 SKNSERAQK-SEPREGQKLPKSR 228
+ E+ +K EP E ++ P+ +
Sbjct: 588 EEKQEKEEKREEPMEEEEEPEQK 610
Score = 31.6 bits (70), Expect = 0.99
Identities = 26/141 (18%), Positives = 64/141 (45%), Gaps = 9/141 (6%)
Query: 119 KDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKA--D 176
K++E ++ R++ ++ A+ L + +D K ++ +K+ + +EKE +
Sbjct: 477 KEAEREEERRREMAKE---AKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADE 533
Query: 177 REVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAE 236
R+ + E+ R++ + E G ++ Q++E R ++ + + E
Sbjct: 534 RDRKREKEELEEIRQRLLAE----GHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEE 589
Query: 237 DLERELKKEKPKHEHKSSSRR 257
E+E K+E+P E + ++
Sbjct: 590 KQEKEEKREEPMEEEEEPEQK 610
Score = 29.6 bits (65), Expect = 3.8
Identities = 23/129 (17%), Positives = 55/129 (42%), Gaps = 12/129 (9%)
Query: 125 DDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKAD-------R 177
D ++++++ R P SE+E+ K+ K++K+E+ +++E+ + R
Sbjct: 559 DAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLR 618
Query: 178 EVQAEQPSSSSPRRKTVKEKDDTGP-----KKHSSKNSERAQKSEPREGQKLPKSRTAYS 232
+ + SS+ T D P +S + ++ ++ P+ G L +
Sbjct: 619 PISSAPSVSSASGNATPNTPGDESPCGIIIPHENSPDQQQPEEHRPKIGLSLKLGASNSP 678
Query: 233 GGAEDLERE 241
G ++R+
Sbjct: 679 GQPNSVKRK 687
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 69.7 bits (169), Expect = 3e-12
Identities = 45/179 (25%), Positives = 86/179 (48%), Gaps = 16/179 (8%)
Query: 147 ESSEDEKPTKKHKKDKKEKKKKKKEK----EKADREVQAEQPSSSSPRRKTVKEKDDTGP 202
E ++ + +K ++ ++EK+K+++EK E+ +E + E+ R+K +EK+
Sbjct: 50 EGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKE---- 105
Query: 203 KKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPK-HEHKSSSRREARE 261
N E +K + ++ +K + RT+ G + + E K+E+ K E K R + RE
Sbjct: 106 ------NKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERE 159
Query: 262 EKTR-IRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSHRHKRARRSRERESSNPSDR 319
K R R+R + + + R R R+R K R ++ RR R++E +R
Sbjct: 160 RKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEER 218
Score = 62.4 bits (150), Expect = 5e-10
Identities = 38/189 (20%), Positives = 91/189 (48%), Gaps = 5/189 (2%)
Query: 119 KDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADRE 178
K+ E + R+ +++ R E ++E+ KK +++K+ K+ ++KEK K +
Sbjct: 61 KERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEK 120
Query: 179 VQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDL 238
+ + S R+ +E+ K+ K ER ++ E +E +K + + G ++
Sbjct: 121 KERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQV----GEKEE 176
Query: 239 ERELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDK 298
ER+ +KE+ + + + +R+E ++E+ R R R + + + ++ R +++
Sbjct: 177 ERK-EKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKER 235
Query: 299 SHRHKRARR 307
R ++ R+
Sbjct: 236 GKRERKERK 244
Score = 62.0 bits (149), Expect = 7e-10
Identities = 46/174 (26%), Positives = 79/174 (45%), Gaps = 16/174 (9%)
Query: 150 EDEKPTKKHKKDKKEKKKKKK-EKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSK 208
E EK K+ + K++K ++KK E+E+ R + E ++ KEK + G + S +
Sbjct: 72 EREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERG--RTSKE 129
Query: 209 NSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTRIRD 268
ER +K E + ++ + R + ERE K+ K + + + E R+EK R
Sbjct: 130 GKERERKEERKREERKERERKKEE---REKERERKERKKRERKQVGEKEEERKEKERKER 186
Query: 269 RGRSSDAHSSWYNGRSEGRSYRSRSRSRD-KSHRHKRARRSRERESSNPSDRWR 321
+ R R E + R R R+ K R K+ R +ER+ ++ WR
Sbjct: 187 KKRE--------RNRKERKKERERKERRERKKERKKKEERKKERQKDRQTN-WR 231
Score = 39.3 bits (90), Expect = 0.005
Identities = 32/156 (20%), Positives = 63/156 (40%), Gaps = 33/156 (21%)
Query: 116 RAPKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKA 175
R K+ +E +++ +E+ E ++ +K ++ K+ KK+++K+ +
Sbjct: 115 RKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEK 174
Query: 176 DREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGA 235
+ E KEK+ KK ER ++ E +E
Sbjct: 175 EEE---------------RKEKERKERKKRERNRKERKKERERKE--------------- 204
Query: 236 EDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGR 271
RE KKE+ K E + R++ R+ R ++RG+
Sbjct: 205 ---RRERKKERKKKEERKKERQKDRQTNWREKERGK 237
Score = 30.4 bits (67), Expect = 2.2
Identities = 24/128 (18%), Positives = 56/128 (43%), Gaps = 5/128 (3%)
Query: 101 KIKGRTIRVDHVSNYRAPKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKK 160
K +GRT + + + EE + R+ +E+ E + + ++ K+
Sbjct: 121 KERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKE 180
Query: 161 DKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPRE 220
+++ ++KK+E+ + +R+ + E+ RR+ KE+ +K + + E
Sbjct: 181 KERK-ERKKRERNRKERKKERER----KERRERKKERKKKEERKKERQKDRQTNWREKER 235
Query: 221 GQKLPKSR 228
G++ K R
Sbjct: 236 GKRERKER 243
Score = 28.9 bits (63), Expect = 6.4
Identities = 17/85 (20%), Positives = 37/85 (43%)
Query: 108 RVDHVSNYRAPKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKK 167
R + R +E + ++ +E+ R E E+ +K ++ KKE++K
Sbjct: 160 RKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERK 219
Query: 168 KKKEKEKADREVQAEQPSSSSPRRK 192
K+++K++ + E+ RK
Sbjct: 220 KERQKDRQTNWREKERGKRERKERK 244
>gi|51243065 zinc finger CCHC-type and RNA binding motif 1 [Homo
sapiens]
Length = 217
Score = 69.7 bits (169), Expect = 3e-12
Identities = 51/187 (27%), Positives = 84/187 (44%), Gaps = 11/187 (5%)
Query: 38 IFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNF 97
+++ LP+ LT D+ +FS+YG++V + +++DK T KSKG F+ + D+ S
Sbjct: 12 VYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFLDKDSAQNCTRAI 71
Query: 98 NGIKIKGRTIRVD-HVSNYRAPKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTK 156
N ++ GR I+ + N RA E + C S LS + +
Sbjct: 72 NNKQLFGRVIKASIAIDNGRA----AEFIRRRNYFDKSKCYECGESGHLSYACPKNMLGE 127
Query: 157 KHKKDKKEKKKKKK--EKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQ 214
+ KKEKKKKKK E E+ EV+ + P ++ + +K E +
Sbjct: 128 REPPKKKEKKKKKKAPEPEEEIEEVEESEDEGEDPALDSLSQ----AIAFQQAKIEEEQK 183
Query: 215 KSEPREG 221
K +P G
Sbjct: 184 KWKPSSG 190
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 69.3 bits (168), Expect = 4e-12
Identities = 43/169 (25%), Positives = 81/169 (47%), Gaps = 18/169 (10%)
Query: 160 KDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPR 219
++ KEK +K+ E+ D ++ E+ ++ +E+++ K+ + +++ R
Sbjct: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDR 287
Query: 220 EGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSW 279
E +K +SR+ +S D ++ +HK S RE R ++R R R RS D
Sbjct: 288 ERRKRSRSRSRHSSRTSD-----RRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERK 342
Query: 280 YNGRSEGR---------SYRSRSRSRDKSHRHKRARRSRERESSNPSDR 319
+ RS R SY+ RS+SRD+ ++ R+S+E+E D+
Sbjct: 343 HRSRSRDRRRSKSRDRKSYKHRSKSRDR----EQDRKSKEKEKRGSDDK 387
Score = 62.0 bits (149), Expect = 7e-10
Identities = 45/199 (22%), Positives = 90/199 (45%), Gaps = 14/199 (7%)
Query: 123 EIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAE 182
+I +L+EK RT P E + EK ++ ++ ++E++++++E+++ E + E
Sbjct: 222 KIKATVEELKEK-LRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEERE 280
Query: 183 QPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLEREL 242
+ + R+ K +HSS+ S+R + K +SR + D R
Sbjct: 281 KERARDRERR----KRSRSRSRHSSRTSDR--RCSRSRDHKRSRSRERRRSRSRDRRRSR 334
Query: 243 KKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSR--SRDKSH 300
++ + +H+S SR ++ R + R R S H S R + R + + + S DK
Sbjct: 335 SHDRSERKHRSRSR-----DRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKS 389
Query: 301 RHKRARRSRERESSNPSDR 319
K R ++ E +N +
Sbjct: 390 SVKSGSREKQSEDTNTESK 408
Score = 53.5 bits (127), Expect = 2e-07
Identities = 42/148 (28%), Positives = 68/148 (45%), Gaps = 14/148 (9%)
Query: 172 KEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAY 231
+ + D + +Q + + TV+E + K+ + + K E +E ++ K R
Sbjct: 205 QSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKER--- 261
Query: 232 SGGAEDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRS 291
+ ERE ++ K + E + + AR+ + R R R RS HSS S+ R RS
Sbjct: 262 -----EREREERERKRRREEEEREKERARDRERRKRSRSRS--RHSS---RTSDRRCSRS 311
Query: 292 RSRSRDKSHRHKRARRSRERESSNPSDR 319
R R +S R +R RSR+R S DR
Sbjct: 312 RDHKRSRS-RERRRSRSRDRRRSRSHDR 338
Score = 42.4 bits (98), Expect = 6e-04
Identities = 39/190 (20%), Positives = 85/190 (44%), Gaps = 27/190 (14%)
Query: 119 KDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADRE 178
K +EE D R +EK R E +E+ K+ +++++ +K++ +++E+ R
Sbjct: 236 KRTEEPDRDERLKKEKQ--EREEREKEREREREERERKRRREEEEREKERARDRERRKRS 293
Query: 179 VQAEQPSSSSPRRKTVKEKD-----------------------DTGPKKHSSKNSERAQK 215
+ SS + R+ + +D D +KH S++ +R ++
Sbjct: 294 RSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDR-RR 352
Query: 216 SEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDA 275
S+ R+ +K K R+ +D + + K+++ + KSS + +RE+++ +
Sbjct: 353 SKSRD-RKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESD 411
Query: 276 HSSWYNGRSE 285
+ NG SE
Sbjct: 412 TKNEVNGTSE 421
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 69.3 bits (168), Expect = 4e-12
Identities = 43/169 (25%), Positives = 81/169 (47%), Gaps = 18/169 (10%)
Query: 160 KDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPR 219
++ KEK +K+ E+ D ++ E+ ++ +E+++ K+ + +++ R
Sbjct: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDR 287
Query: 220 EGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSW 279
E +K +SR+ +S D ++ +HK S RE R ++R R R RS D
Sbjct: 288 ERRKRSRSRSRHSSRTSD-----RRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERK 342
Query: 280 YNGRSEGR---------SYRSRSRSRDKSHRHKRARRSRERESSNPSDR 319
+ RS R SY+ RS+SRD+ ++ R+S+E+E D+
Sbjct: 343 HRSRSRDRRRSKSRDRKSYKHRSKSRDR----EQDRKSKEKEKRGSDDK 387
Score = 62.0 bits (149), Expect = 7e-10
Identities = 45/199 (22%), Positives = 90/199 (45%), Gaps = 14/199 (7%)
Query: 123 EIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAE 182
+I +L+EK RT P E + EK ++ ++ ++E++++++E+++ E + E
Sbjct: 222 KIKATVEELKEK-LRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEERE 280
Query: 183 QPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLEREL 242
+ + R+ K +HSS+ S+R + K +SR + D R
Sbjct: 281 KERARDRERR----KRSRSRSRHSSRTSDR--RCSRSRDHKRSRSRERRRSRSRDRRRSR 334
Query: 243 KKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSR--SRDKSH 300
++ + +H+S SR ++ R + R R S H S R + R + + + S DK
Sbjct: 335 SHDRSERKHRSRSR-----DRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKS 389
Query: 301 RHKRARRSRERESSNPSDR 319
K R ++ E +N +
Sbjct: 390 SVKSGSREKQSEDTNTESK 408
Score = 53.5 bits (127), Expect = 2e-07
Identities = 42/148 (28%), Positives = 68/148 (45%), Gaps = 14/148 (9%)
Query: 172 KEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAY 231
+ + D + +Q + + TV+E + K+ + + K E +E ++ K R
Sbjct: 205 QSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKER--- 261
Query: 232 SGGAEDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRS 291
+ ERE ++ K + E + + AR+ + R R R RS HSS S+ R RS
Sbjct: 262 -----EREREERERKRRREEEEREKERARDRERRKRSRSRS--RHSS---RTSDRRCSRS 311
Query: 292 RSRSRDKSHRHKRARRSRERESSNPSDR 319
R R +S R +R RSR+R S DR
Sbjct: 312 RDHKRSRS-RERRRSRSRDRRRSRSHDR 338
Score = 42.4 bits (98), Expect = 6e-04
Identities = 39/190 (20%), Positives = 85/190 (44%), Gaps = 27/190 (14%)
Query: 119 KDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADRE 178
K +EE D R +EK R E +E+ K+ +++++ +K++ +++E+ R
Sbjct: 236 KRTEEPDRDERLKKEKQ--EREEREKEREREREERERKRRREEEEREKERARDRERRKRS 293
Query: 179 VQAEQPSSSSPRRKTVKEKD-----------------------DTGPKKHSSKNSERAQK 215
+ SS + R+ + +D D +KH S++ +R ++
Sbjct: 294 RSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDR-RR 352
Query: 216 SEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDA 275
S+ R+ +K K R+ +D + + K+++ + KSS + +RE+++ +
Sbjct: 353 SKSRD-RKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESD 411
Query: 276 HSSWYNGRSE 285
+ NG SE
Sbjct: 412 TKNEVNGTSE 421
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 68.9 bits (167), Expect = 6e-12
Identities = 65/244 (26%), Positives = 100/244 (40%), Gaps = 22/244 (9%)
Query: 81 FLCYEDQRSTILAVDNFNGIKIKGRTIR-VDHVSNYRAPKDSEEIDDVTRQLQEKGCGAR 139
F+ Y D + A++ +G ++ GR IR V+ R + +R +
Sbjct: 147 FVSYSDMKR---ALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRK 203
Query: 140 TPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDD 199
+ S S S S K + + + + K + + R +++ S SP ++ + +
Sbjct: 204 SRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSR---SKKEKSRSPSKEKSRSRSH 260
Query: 200 TGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREA 259
+ K S + +K + + PKSR+ K K K +S RR
Sbjct: 261 SAGKSRSKSKDQAEEKIQNNDNVGKPKSRSP----------SRHKSKSKSRSRSQERR-V 309
Query: 260 REEKTRIRDRGRSSDA--HSSWYNGRSEGRSYRSRSRSRDKSHRHKRARRSRERESSNPS 317
EEK RGRS + S RS+G S RSRSRSR KS + KR R R RE S
Sbjct: 310 EEEKRGSVSRGRSQEKSLRQSRSRSRSKGGS-RSRSRSRSKS-KDKRKGRKRSREESRSR 367
Query: 318 DRWR 321
R R
Sbjct: 368 SRSR 371
Score = 65.5 bits (158), Expect = 6e-11
Identities = 53/199 (26%), Positives = 89/199 (44%), Gaps = 18/199 (9%)
Query: 138 ARTPSPSLSESSEDEKPTKKHKKDKKEK--KKKKKEKEKADREVQAE----QPSSSSPRR 191
+R+ S S S+ + P+K+ + + K + K K++A+ ++Q +P S SP R
Sbjct: 234 SRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSR 293
Query: 192 KTVKEKDDTGPKKHSSKNSERAQKSEPREGQK---LPKSRTAYSGGAEDLERELKKEKPK 248
K K + ++ + +R S R +K +SR+ GG+ R K K K
Sbjct: 294 HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDK 353
Query: 249 --------HEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSH 300
E +S SR ++ E++R R R S A SS + + +SRS SR S
Sbjct: 354 RKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSK 413
Query: 301 RHKRAR-RSRERESSNPSD 318
+ A+ S +RE S+
Sbjct: 414 EREHAKSESSQREGRGESE 432
Score = 53.9 bits (128), Expect = 2e-07
Identities = 52/216 (24%), Positives = 90/216 (41%), Gaps = 27/216 (12%)
Query: 111 HVSNYRAPKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHK---KDKKEKKK 167
H S ++ S+E R+++E+ G+ + S +S + + K + + +
Sbjct: 294 HKSKSKSRSRSQE-----RRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRS 348
Query: 168 KKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKS 227
K K+K K + + E S S R K+ + + K SK +A S+ ++ + +S
Sbjct: 349 KSKDKRKGRKRSREESRSRSRSRSKSERSR------KRGSKRDSKAGSSKKKKKEDTDRS 402
Query: 228 RTAYSGGAEDLERE-LKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEG 286
++ + ERE K E + E + S ++TR R R S +
Sbjct: 403 QSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPN--------- 453
Query: 287 RSYRSRSRSRDKSHRHKRAR-RSRERESSNPSDRWR 321
S SRSR KS R+R +SR R +S R R
Sbjct: 454 --LPSESRSRSKSASKTRSRSKSRSRSASRSPSRSR 487
Score = 40.4 bits (93), Expect = 0.002
Identities = 51/168 (30%), Positives = 66/168 (39%), Gaps = 33/168 (19%)
Query: 129 RQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSS 188
R +E +R+ S S K K K KK+KE DR S S
Sbjct: 359 RSREESRSRSRSRSKSERSRKRGSKRDSKAGSSK------KKKKEDTDRS------QSRS 406
Query: 189 PRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPK 248
P R KE++ K SS+ R + Q+ +SR+ R K KP
Sbjct: 407 PSRSVSKEREHA--KSESSQREGRGESENAGTNQE-TRSRS----------RSNSKSKPN 453
Query: 249 HEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSR 296
+S SR ++ KTR R + RS A RS RS RSRS SR
Sbjct: 454 LPSESRSRSKS-ASKTRSRSKSRSRSA------SRSPSRS-RSRSHSR 493
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 68.9 bits (167), Expect = 6e-12
Identities = 63/249 (25%), Positives = 104/249 (41%), Gaps = 27/249 (10%)
Query: 100 IKIKGRTIRVDHVSNYRAPKDSEE----IDDVTRQLQEKGCGARTPSPSLSESSEDEKPT 155
+++K R I DH + +P E + D +E+ + ++ ++
Sbjct: 399 VRVKERKI-TDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAK 457
Query: 156 KKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPR-RKTVKEK----DDTGPKKHSSKNS 210
K + KEK K K+ K +R + S S R + VKEK D G + S++
Sbjct: 458 SKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSK 517
Query: 211 ERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREE-------- 262
E++++ E + + A+ RE K KH + S +R +R
Sbjct: 518 EKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRS 577
Query: 263 KTRIRDRGRSSDAH-----SSWYNGRSEGRSYRS---RSRSRDKSHRHKRARRS-RERES 313
+T RDR RS + H GRS R R+ RSRS+D+ R + +R S RE
Sbjct: 578 RTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQ 637
Query: 314 SNPSDRWRH 322
S D++R+
Sbjct: 638 SRNKDKYRN 646
Score = 60.1 bits (144), Expect = 3e-09
Identities = 55/216 (25%), Positives = 89/216 (41%), Gaps = 32/216 (14%)
Query: 130 QLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSP 189
+L E R+P D + + K EK+KK K+ + +E + S
Sbjct: 387 ELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDD 446
Query: 190 RRKT-----------VKEKDDTGPKKHSSKNSERAQK-----SEPREGQKLPKSRTAYSG 233
+ K K K+ + K+ SK++ +K S+ R+ + + +
Sbjct: 447 KYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDS 506
Query: 234 GAEDLERELKKEKPK--------HEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSE 285
+D ER KEK K H+H S S+ + R ++R R+ + HS YN R+
Sbjct: 507 KGKDQERSRSKEKSKQLESKSNEHDH-SKSKEKDRRAQSRSRECDITKGKHS--YNSRT- 562
Query: 286 GRSYRSRSRSRDKSHRHKRARRSRERESSNPSDRWR 321
R RSRSRD+S R + R+R S R+R
Sbjct: 563 ----RERSRSRDRSRRVRSRTHDRDRSRSKEYHRYR 594
Score = 60.1 bits (144), Expect = 3e-09
Identities = 56/224 (25%), Positives = 97/224 (43%), Gaps = 18/224 (8%)
Query: 110 DHVSNY--RAPKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKK 167
DH SN R + + E DD + +K +++ S S +S E+ +K ++ ++K +
Sbjct: 428 DHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRS 487
Query: 168 KKK--------EKEK-ADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEP 218
+ K EKEK +D + + ++ S S + K ++ K + S + RAQ S
Sbjct: 488 RSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQ-SRS 546
Query: 219 RE-----GQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRSS 273
RE G+ SRT + D R ++ + +S S+ R + R RGRS
Sbjct: 547 RECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRD-RSRSKEYHRYREQEYRRRGRSR 605
Query: 274 DAHSSWYNGRSEGRSYRSRSRSRDKSHRHKRARRSRERESSNPS 317
GRS + R R R S R + R++++ + S
Sbjct: 606 SRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQES 649
Score = 57.8 bits (138), Expect = 1e-08
Identities = 54/229 (23%), Positives = 90/229 (39%), Gaps = 24/229 (10%)
Query: 98 NGIKIKGRTIRVDHVSNYRAPKDSEEIDDVTRQ------LQEKGCGARTPSPSLSESSED 151
+G KIKGR R YR P S D R QE R S +
Sbjct: 329 SGRKIKGRGPR-----RYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKG 383
Query: 152 EKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSE 211
+K K+ + + KE++ D +E P+ + + K VK+ ++ +NSE
Sbjct: 384 DKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSE 443
Query: 212 RAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGR 271
+ K + + ++ A+ R KEK K + + S E++ R R +GR
Sbjct: 444 KDDKYKNKVKKR-----------AKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGR 492
Query: 272 S-SDAHSSWYNGRSEGRSYRSRSRSRDKSHRHKRARRSRERESSNPSDR 319
+ S+G+ + RSRS++KS + + + S DR
Sbjct: 493 DHENVKEKEKQSDSKGKD-QERSRSKEKSKQLESKSNEHDHSKSKEKDR 540
Score = 50.4 bits (119), Expect = 2e-06
Identities = 42/199 (21%), Positives = 93/199 (46%), Gaps = 12/199 (6%)
Query: 119 KDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADRE 178
+D E + + +Q KG S S +S + E + +H K ++K ++ + + +
Sbjct: 492 RDHENVKEKEKQSDSKGKDQER-SRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECD 550
Query: 179 VQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSE-----PREGQKLPKSRTAYSG 233
+ + S +S R+ + +D + + + + +R++ E +E ++ +SR+
Sbjct: 551 ITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERR 610
Query: 234 GAEDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSW--YNGRSEGRSY-R 290
R + + + + +SS R E+ ++R +D+ R+ ++ SS N SE R Y +
Sbjct: 611 TPPGRSRSKDRRRRRRDSRSSEREES---QSRNKDKYRNQESKSSHRKENSESEKRMYSK 667
Query: 291 SRSRSRDKSHRHKRARRSR 309
SR + + R K+A R +
Sbjct: 668 SRDHNSSNNSREKKADRDQ 686
Score = 49.3 bits (116), Expect = 5e-06
Identities = 56/211 (26%), Positives = 83/211 (39%), Gaps = 37/211 (17%)
Query: 144 SLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPK 203
S E K K+ KK K +D ++ S SS +EK K
Sbjct: 173 SCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKK 232
Query: 204 KHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHE-----------HK 252
KH + + R K E ++ +K KS ++ S AE+LE + + E K
Sbjct: 233 KH--RKNSRKHKKEKKKRKKSKKSASSES-EAENLEAQPQSTVRPEEIPPIPENRFLMRK 289
Query: 253 SSSRREAREEKTRIRDRGRSSDAHSS-----------WYNGRS-EGRSYR-----SRSRS 295
S + + +E K R R+R R + +S +GR +GR R SRSRS
Sbjct: 290 SPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRS 349
Query: 296 RDKSHR-----HKRARRSR-ERESSNPSDRW 320
RD+ R H R R +R + +RW
Sbjct: 350 RDRFRRSETPPHWRQEMQRAQRMRVSSGERW 380
Score = 49.3 bits (116), Expect = 5e-06
Identities = 47/203 (23%), Positives = 77/203 (37%), Gaps = 8/203 (3%)
Query: 113 SNYRAPKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKK-- 170
S+ + DS+ D + T S + K ++KHKK+KK++KK KK
Sbjct: 196 SSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSA 255
Query: 171 EKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTA 230
E ++A+ S+ P ++ +K K E+ +K+ RE ++ +
Sbjct: 256 SSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERER--ECNPP 313
Query: 231 YSGGAEDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYR 290
S A R L + RR ++R RDR R S+ W + R
Sbjct: 314 NSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMR 373
Query: 291 SRSRSR----DKSHRHKRARRSR 309
S R DKS ++ R
Sbjct: 374 VSSGERWIKGDKSELNEIKENQR 396
Score = 37.0 bits (84), Expect = 0.024
Identities = 29/145 (20%), Positives = 65/145 (44%), Gaps = 14/145 (9%)
Query: 139 RTPSPSLSESSEDEKPTKKHKK-DKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEK 197
RTP P S S + + + + +++E + + K+K + + + +S ++ +
Sbjct: 610 RTP-PGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKS 668
Query: 198 DDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRR 257
D H+S N+ R +K++ + P S+ S +L+ + K K + +SS +
Sbjct: 669 RD-----HNSSNNSREKKADRDQS---PFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEK 720
Query: 258 EAR----EEKTRIRDRGRSSDAHSS 278
E + +E + ++ + D SS
Sbjct: 721 ENQKSKGQENDHVHEKNKKFDHESS 745
Score = 36.2 bits (82), Expect = 0.040
Identities = 30/171 (17%), Positives = 69/171 (40%), Gaps = 25/171 (14%)
Query: 148 SSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSS 207
S E+ T + K++++++++ ++RE S S + + ++ + +
Sbjct: 604 SRSRERRTPPGRSRSKDRRRRRRDSRSSERE------ESQSRNKDKYRNQESKSSHRKEN 657
Query: 208 KNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTRIR 267
SE+ S+ R+ SR + + ++K+ +E KSS + +EK
Sbjct: 658 SESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKI--- 714
Query: 268 DRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSHRHKRARRSRERESSNPSD 318
RS +S+ ++ H H++ ++ + ESS +D
Sbjct: 715 ---------------RSSVEKENQKSKGQENDHVHEKNKKF-DHESSPGTD 749
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 68.9 bits (167), Expect = 6e-12
Identities = 55/186 (29%), Positives = 83/186 (44%), Gaps = 18/186 (9%)
Query: 145 LSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKK 204
+ ++ E K K K +KEKK+ + ++ R +E S RK E K+
Sbjct: 1796 VKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKS-----RKRTSESRSRARKR 1850
Query: 205 HSSKNSERAQ---KSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRR---- 257
S S R+Q +S R ++ +SR+ S G + +E +K PKH KS R+
Sbjct: 1851 SSKSKSHRSQTRSRSRSRRRRRSSRSRSK-SRGRRSVSKEKRKRSPKHRSKSRERKRKRS 1909
Query: 258 EAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSHRHKRARRSR--ERESSN 315
+R+ + +R R R+ S + R RSRS R +S +RRSR R S
Sbjct: 1910 SSRDNRKTVRARSRTPSRRS---RSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRT 1966
Query: 316 PSDRWR 321
PS R R
Sbjct: 1967 PSRRSR 1972
Score = 63.2 bits (152), Expect = 3e-10
Identities = 65/223 (29%), Positives = 89/223 (39%), Gaps = 49/223 (21%)
Query: 146 SESSEDEKPTKK--------HKKDKKEKKKKKKEKEKAD----REVQAEQPSSSSPRRKT 193
SESS +EK + H+K KK K + K EKEK R SS RK
Sbjct: 1780 SESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKR 1839
Query: 194 VKEKDDTGPKKHSSKNSERAQ---KSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHE 250
E K+ S S R+Q +S R ++ +SR+ S G + +E +K PKH
Sbjct: 1840 TSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSK-SRGRRSVSKEKRKRSPKHR 1898
Query: 251 HKSSSRRE----AREEKTRIRDRGRSSDAHSSWYN------GRSEGR------------- 287
KS R+ +R+ + +R R R+ S + RS GR
Sbjct: 1899 SKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSR 1958
Query: 288 ---------SYRSRSRSRDKSHRHKRARRSRERESSNPSDRWR 321
S RSR+ SR +S R R+ R S PS R R
Sbjct: 1959 TPSRRSRTPSRRSRTPSR-RSRTPSRRSRTPSRRSRTPSRRRR 2000
Score = 55.1 bits (131), Expect = 8e-08
Identities = 45/139 (32%), Positives = 62/139 (44%), Gaps = 10/139 (7%)
Query: 182 EQPSSSSPRRKT-----VKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAE 236
E+ S SS K VK KD T K +KN ++ +K + R+ +SR+ S +E
Sbjct: 1777 ERASESSSEEKDDYEIFVKVKD-THEKSKKNKNRDKGEKEKKRDSSL--RSRSKRSKSSE 1833
Query: 237 DLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGR-SYRSRSRS 295
R+ E K SS+ ++ +TR R R R SS +S GR S R
Sbjct: 1834 HKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRR-RRSSRSRSKSRGRRSVSKEKRK 1892
Query: 296 RDKSHRHKRARRSRERESS 314
R HR K R R+R SS
Sbjct: 1893 RSPKHRSKSRERKRKRSSS 1911
Score = 42.7 bits (99), Expect = 4e-04
Identities = 53/218 (24%), Positives = 85/218 (38%), Gaps = 21/218 (9%)
Query: 113 SNYRAPKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKE----KKKK 168
S +++ K + E R+ K R+ + S S S + ++ K + K+K+
Sbjct: 1832 SEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKR 1891
Query: 169 KKE-KEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKS 227
K+ K ++ + + SSS RKTV+ + T ++ S R + +S
Sbjct: 1892 KRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRR-----------RS 1940
Query: 228 RTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGR 287
R+ + + + P ++ SRR +R R R R S S S R
Sbjct: 1941 RSVGRRRSFSISPSRRSRTPSRRSRTPSRR-SRTPSRRSRTPSRRSRTPSRRSRTPSRRR 1999
Query: 288 SYRSRSRSRDKSHRHKRARRS----RERESSNPSDRWR 321
RS R R S R RRS R R S +P R R
Sbjct: 2000 RSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKR 2037
Score = 42.0 bits (97), Expect = 7e-04
Identities = 21/50 (42%), Positives = 31/50 (62%), Gaps = 1/50 (2%)
Query: 144 SLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKT 193
S+ DE PTKK KK KK K KKKK+K++ +++ + QP S + K+
Sbjct: 94 SVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYK-RQPEESESKTKS 142
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 68.9 bits (167), Expect = 6e-12
Identities = 55/186 (29%), Positives = 83/186 (44%), Gaps = 18/186 (9%)
Query: 145 LSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKK 204
+ ++ E K K K +KEKK+ + ++ R +E S RK E K+
Sbjct: 1796 VKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKS-----RKRTSESRSRARKR 1850
Query: 205 HSSKNSERAQ---KSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRR---- 257
S S R+Q +S R ++ +SR+ S G + +E +K PKH KS R+
Sbjct: 1851 SSKSKSHRSQTRSRSRSRRRRRSSRSRSK-SRGRRSVSKEKRKRSPKHRSKSRERKRKRS 1909
Query: 258 EAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSHRHKRARRSR--ERESSN 315
+R+ + +R R R+ S + R RSRS R +S +RRSR R S
Sbjct: 1910 SSRDNRKTVRARSRTPSRRS---RSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRT 1966
Query: 316 PSDRWR 321
PS R R
Sbjct: 1967 PSRRSR 1972
Score = 63.2 bits (152), Expect = 3e-10
Identities = 65/223 (29%), Positives = 89/223 (39%), Gaps = 49/223 (21%)
Query: 146 SESSEDEKPTKK--------HKKDKKEKKKKKKEKEKAD----REVQAEQPSSSSPRRKT 193
SESS +EK + H+K KK K + K EKEK R SS RK
Sbjct: 1780 SESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKR 1839
Query: 194 VKEKDDTGPKKHSSKNSERAQ---KSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHE 250
E K+ S S R+Q +S R ++ +SR+ S G + +E +K PKH
Sbjct: 1840 TSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSK-SRGRRSVSKEKRKRSPKHR 1898
Query: 251 HKSSSRRE----AREEKTRIRDRGRSSDAHSSWYN------GRSEGR------------- 287
KS R+ +R+ + +R R R+ S + RS GR
Sbjct: 1899 SKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSR 1958
Query: 288 ---------SYRSRSRSRDKSHRHKRARRSRERESSNPSDRWR 321
S RSR+ SR +S R R+ R S PS R R
Sbjct: 1959 TPSRRSRTPSRRSRTPSR-RSRTPSRRSRTPSRRSRTPSRRRR 2000
Score = 55.1 bits (131), Expect = 8e-08
Identities = 45/139 (32%), Positives = 62/139 (44%), Gaps = 10/139 (7%)
Query: 182 EQPSSSSPRRKT-----VKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAE 236
E+ S SS K VK KD T K +KN ++ +K + R+ +SR+ S +E
Sbjct: 1777 ERASESSSEEKDDYEIFVKVKD-THEKSKKNKNRDKGEKEKKRDSSL--RSRSKRSKSSE 1833
Query: 237 DLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGR-SYRSRSRS 295
R+ E K SS+ ++ +TR R R R SS +S GR S R
Sbjct: 1834 HKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRR-RRSSRSRSKSRGRRSVSKEKRK 1892
Query: 296 RDKSHRHKRARRSRERESS 314
R HR K R R+R SS
Sbjct: 1893 RSPKHRSKSRERKRKRSSS 1911
Score = 42.7 bits (99), Expect = 4e-04
Identities = 53/218 (24%), Positives = 85/218 (38%), Gaps = 21/218 (9%)
Query: 113 SNYRAPKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKE----KKKK 168
S +++ K + E R+ K R+ + S S S + ++ K + K+K+
Sbjct: 1832 SEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKR 1891
Query: 169 KKE-KEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKS 227
K+ K ++ + + SSS RKTV+ + T ++ S R + +S
Sbjct: 1892 KRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRR-----------RS 1940
Query: 228 RTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGR 287
R+ + + + P ++ SRR +R R R R S S S R
Sbjct: 1941 RSVGRRRSFSISPSRRSRTPSRRSRTPSRR-SRTPSRRSRTPSRRSRTPSRRSRTPSRRR 1999
Query: 288 SYRSRSRSRDKSHRHKRARRS----RERESSNPSDRWR 321
RS R R S R RRS R R S +P R R
Sbjct: 2000 RSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKR 2037
Score = 42.0 bits (97), Expect = 7e-04
Identities = 21/50 (42%), Positives = 31/50 (62%), Gaps = 1/50 (2%)
Query: 144 SLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKT 193
S+ DE PTKK KK KK K KKKK+K++ +++ + QP S + K+
Sbjct: 94 SVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYK-RQPEESESKTKS 142
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 68.6 bits (166), Expect = 7e-12
Identities = 49/184 (26%), Positives = 83/184 (45%), Gaps = 16/184 (8%)
Query: 142 SPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTG 201
S S E EK ++ +++ KE++K+++ DR ++ + S R + +D G
Sbjct: 288 SSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKG 347
Query: 202 PKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREARE 261
++ + E+ + R + K R G + ERE +E+ K + SR E E
Sbjct: 348 DRRDRDREREKENERGRRRDRDYDKER----GNEREKERERSRERSKEQR---SRGEVEE 400
Query: 262 EK-------TRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSHRHKRARRSRERESS 314
+K R RD R S RS R +RSRSRSR+ R + RS+E+ S
Sbjct: 401 KKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSR--SRSKEKSSK 458
Query: 315 NPSD 318
+ ++
Sbjct: 459 HKNE 462
Score = 61.2 bits (147), Expect = 1e-09
Identities = 52/178 (29%), Positives = 87/178 (48%), Gaps = 16/178 (8%)
Query: 150 EDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKE-KDDTGPK--KHS 206
E+E+ ++ + KE+ +++++ + RE EQ S K KE KDD + K
Sbjct: 359 ENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRD 418
Query: 207 SKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREARE----- 261
SK ++ +S RE + +SR+ +G + K K K+E K S + +R
Sbjct: 419 SKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGR 478
Query: 262 ----EKTRIRDRGRSSDAHSSWYNGRSEGRSY-RSRSRSRDKSHRHKRAR-RSRERES 313
EK++ R+ S + S RS+ RS+ R S S+D+S +H R R +S E+ES
Sbjct: 479 TDSVEKSKKREHSPSKE--KSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQES 534
Score = 57.0 bits (136), Expect = 2e-08
Identities = 45/202 (22%), Positives = 86/202 (42%), Gaps = 15/202 (7%)
Query: 120 DSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREV 179
D E + RQ E+ R S S + ++ + ++ + + + K DR
Sbjct: 292 DRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRR- 350
Query: 180 QAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLE 239
R + +++++ G ++ + ER + E + +S+ S G E E
Sbjct: 351 ---------DRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRG-EVEE 400
Query: 240 RELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKS 299
++ K++K H+ +R++++EK R R R S RS RSRSRS++KS
Sbjct: 401 KKHKEDKDDRRHR-DDKRDSKKEKKHSRSRSRERKHRS---RSRSRNAGKRSRSRSKEKS 456
Query: 300 HRHKRARRSRERESSNPSDRWR 321
+HK + + + S + R
Sbjct: 457 SKHKNESKEKSNKRSRSGSQGR 478
Score = 56.6 bits (135), Expect = 3e-08
Identities = 45/171 (26%), Positives = 77/171 (45%), Gaps = 18/171 (10%)
Query: 139 RTPSPSLSESSEDEKPTKKHKKDKKEK-----KKKKKEKEKADREVQAEQPSSSSPRRKT 193
R+ S + S E KKHK+DK ++ K+ K+++K R E+ S R +
Sbjct: 384 RSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRN 443
Query: 194 VKEKDDTGPKKHSSKN-SERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHK 252
++ + K+ SSK+ +E +KS R SR+ G + +E+ K+E + K
Sbjct: 444 AGKRSRSRSKEKSSKHKNESKEKSNKR-------SRSGSQGRTDSVEKSKKREHSPSKEK 496
Query: 253 SSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSHRHK 303
S R ++ E++ RD S D RS S++K H++K
Sbjct: 497 SRKRSRSK-ERSHKRDHSDSKDQSDK----HDRRRSQSIEQESQEKQHKNK 542
Score = 55.5 bits (132), Expect = 6e-08
Identities = 47/163 (28%), Positives = 71/163 (43%), Gaps = 22/163 (13%)
Query: 159 KKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEP 218
+K+ ++ K + K K D + AE+ RR++ + P++ ++ R S
Sbjct: 226 QKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSR---SHH 282
Query: 219 REGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSS 278
REG G+ +REL++EK + +R RE K R ++R RS
Sbjct: 283 REGH-----------GSSSFDRELEREKER-------QRLEREAKEREKERRRSRSIDRG 324
Query: 279 WYNGRSEGRSYRSRSRSRDKSHRHKRARRSRERESSNPSDRWR 321
RS R R RSRSR + + R R RERE N R R
Sbjct: 325 LERRRSRSRE-RHRSRSRSRDRKGDRRDRDREREKENERGRRR 366
Score = 30.0 bits (66), Expect = 2.9
Identities = 24/143 (16%), Positives = 52/143 (36%), Gaps = 2/143 (1%)
Query: 115 YRAPKDSEEIDDVTR--QLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEK 172
++ KD D R + ++K +R+ S K+ + KEK K K +
Sbjct: 403 HKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNE 462
Query: 173 EKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYS 232
K ++ S +K + P K S+ R+++ + K ++
Sbjct: 463 SKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKH 522
Query: 233 GGAEDLERELKKEKPKHEHKSSS 255
E + ++ +H++K +
Sbjct: 523 DRRRSQSIEQESQEKQHKNKDET 545
>gi|20911035 peptidylprolyl isomerase-like 4 [Homo sapiens]
Length = 492
Score = 68.2 bits (165), Expect = 1e-11
Identities = 68/276 (24%), Positives = 118/276 (42%), Gaps = 47/276 (17%)
Query: 48 TEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNFNGIKIKGRTI 107
T+ D+ +FS++G I + ++RD KTG+S + F+ +E + A + + I R I
Sbjct: 252 TDEDLEIIFSRFGPIRSCEVIRDWKTGESLCYAFIEFEKEEDCEKAFFKMDNVLIDDRRI 311
Query: 108 RVDHVSNYRAPKDSEEIDDVTRQLQEKGCGAR-TPSPSLSESSEDEKPTKKHKKDKKEKK 166
VD +++ KG G + T S E +KP KDK + K
Sbjct: 312 HVD-------------FSQSVAKVKWKGKGGKYTKSDFKEYEKEQDKPPNLVLKDKVKPK 358
Query: 167 KKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPK 226
+ K D QAE SS KKH K +++ E + +
Sbjct: 359 QDTKYDLILDE--QAEDSKSSHSHTS----------KKHKKKTHHCSEEKEDEDYMPIKN 406
Query: 227 SRTAYSGGAEDLEREL-----KKEKPKHEHKSSSRREAREEKTRIRDR---GRSSDAHSS 278
+ +D+ RE+ ++E+ E + S +R+ + ++R R R G S++H S
Sbjct: 407 TN-------QDIYREMGFGHYEEEESCWEKQKSEKRDRTQNRSRSRSRERDGHYSNSHKS 459
Query: 279 WYNGRSEGRSYRSRSRSRDKSHRHKRARRSRERESS 314
Y R RS+ RD+S + ++S+++E S
Sbjct: 460 KY---QTDLYERERSKKRDRS---RSPKKSKDKEKS 489
>gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens]
Length = 221
Score = 66.6 bits (161), Expect = 3e-11
Identities = 48/201 (23%), Positives = 84/201 (41%), Gaps = 7/201 (3%)
Query: 43 LPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNFNGIKI 102
L Y + + VF +YG + ++ + RD+ T +S+GF F+ + D+R A+D +G +
Sbjct: 21 LTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAMDGAVL 80
Query: 103 KGRTIRVDHVSNYRAPKDSEEI--DDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKK 160
GR +RV ++ Y P DS R+ G G R+ SP S ++ +
Sbjct: 81 DGRELRV-QMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSR 139
Query: 161 DKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPRE 220
+ + K R + +S S + K K + + S S +S P
Sbjct: 140 SRSRYSRSKSRSRTRSR----SRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPV 195
Query: 221 GQKLPKSRTAYSGGAEDLERE 241
++ KSR+ + E E
Sbjct: 196 SKRESKSRSRSKSPPKSPEEE 216
Score = 38.9 bits (89), Expect = 0.006
Identities = 41/134 (30%), Positives = 53/134 (39%), Gaps = 20/134 (14%)
Query: 184 PSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPRE-GQKLPKSRTAYSGGAEDLEREL 242
P S RR + G S++ R ++S R + +SR+ YS
Sbjct: 96 PDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYS---------- 145
Query: 243 KKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSHRH 302
KS SR +R T R S + SS + RS RS RSRSRSR
Sbjct: 146 -------RSKSRSRTRSRSRSTSKSRSARRSKSKSSSVS-RSRSRS-RSRSRSRSPPPVS 196
Query: 303 KRARRSRERESSNP 316
KR +SR R S P
Sbjct: 197 KRESKSRSRSKSPP 210
Score = 38.5 bits (88), Expect = 0.008
Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 2/119 (1%)
Query: 204 KHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEK 263
K ++++ A +G++L Y G D + P+ R +R +
Sbjct: 65 KRDAEDAMDAMDGAVLDGRELRVQMARY-GRPPDSHHSRRGPPPRRYGGGGYGRRSRSPR 123
Query: 264 TRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKS-HRHKRARRSRERESSNPSDRWR 321
R R R RS S R RSR+RSR +S + + ARRS+ + SS R R
Sbjct: 124 RRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSR 182
>gi|7661936 scaffold attachment factor B2 [Homo sapiens]
Length = 953
Score = 66.6 bits (161), Expect = 3e-11
Identities = 62/286 (21%), Positives = 124/286 (43%), Gaps = 20/286 (6%)
Query: 38 IFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNF 97
+++ GL D+ +FS+YG++V +V + ++ ++ + F+ + +
Sbjct: 409 LWVSGLSSTTRATDLKNLFSKYGKVVGAKVVTNARSPGARCYGFVTMSTSDEATKCISHL 468
Query: 98 NGIKIKGRTIRVDHVSNYRAPKDSEEIDDVTRQLQEKGCGARTPSPSLS-ESSEDEKPTK 156
+ ++ GR I V+ N A K + + + ++ R S + E + +K K
Sbjct: 469 HRTELHGRMISVEKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEK 528
Query: 157 KHKKDKKEKKKKKKEKEKAD-------REVQAEQPSSSSPRRKTVKEKDDTGP---KKHS 206
KK++K+ + KKE++ D + + S R V +K P K +
Sbjct: 529 IEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTT 588
Query: 207 SKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREARE-EKTR 265
S++ ER+ KS+ R+ + K + L + KE+ + E + RE RE E+ R
Sbjct: 589 SRSKERSSKSQDRKSESKEK--------RDILSFDKIKEQRERERQRQREREIRETERRR 640
Query: 266 IRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSHRHKRARRSRER 311
R++ +++ + + R R R + + R +R R RER
Sbjct: 641 EREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERER 686
Score = 38.5 bits (88), Expect = 0.008
Identities = 46/257 (17%), Positives = 96/257 (37%), Gaps = 29/257 (11%)
Query: 59 YGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNFNG--IKIKGRTIRVDHVSNYR 116
+G ++++ +++ GK C E ++ + +VD + IKI+ I+ + +
Sbjct: 474 HGRMISVEKAKNEPAGKKLSDRKEC-EVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKK 532
Query: 117 APKDSEEIDDVTRQLQEKGCGARTPS----------------------PSLS-ESSEDEK 153
K E+I + E G S P +S +++ K
Sbjct: 533 EEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSK 592
Query: 154 PTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERA 213
+D+K + K+K++ D+ + + R + ++E + ++ +
Sbjct: 593 ERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLE 652
Query: 214 QKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTRI---RDRG 270
E +E +L + R + LERE + + + RE R+E+ RI R+
Sbjct: 653 AFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHREREEL 712
Query: 271 RSSDAHSSWYNGRSEGR 287
R + R GR
Sbjct: 713 RRQQEQLRYEQERRPGR 729
Score = 31.6 bits (70), Expect = 0.99
Identities = 31/169 (18%), Positives = 70/169 (41%), Gaps = 8/169 (4%)
Query: 152 EKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSE 211
E+ ++ ++ + + ++++E+E+ +RE + E + + +E+ ++ +
Sbjct: 622 ERERQRQREREIRETERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERER 681
Query: 212 RAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGR 271
++ RE ++ + R E + RE +E+ + + + + R R D R
Sbjct: 682 MERERLERERMRVERERRKEQ---ERIHRE--REELRRQQEQLRYEQERRPGRRPYDLDR 736
Query: 272 SSDAHSSWYNGRSEGRSYRSRSRSRDKSHR-HKRARRSRERESSNPSDR 319
DA+ W G+ R R+ HR H R R + + DR
Sbjct: 737 RDDAY--WPEGKRVAMEDRYRADFPRPDHRFHDFDHRDRGQYQDHAIDR 783
>gi|187960109 RNA binding motif protein 28 [Homo sapiens]
Length = 759
Score = 63.5 bits (153), Expect = 2e-10
Identities = 48/230 (20%), Positives = 102/230 (44%), Gaps = 8/230 (3%)
Query: 36 AWIFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVD 95
A + + L ++ +E D+ VF+Q+G ++ +N+ R K GK +GF F+ +++ A+
Sbjct: 114 ARLIIRNLSFKCSEDDLKTVFAQFGAVLEVNIPR-KPDGKMRGFGFVQFKNLLEAGKALK 172
Query: 96 NFNGIKIKGRTIRVDHVSNYRAPKDSEEIDDV-TRQLQEKGCGARTPSPSLSESSEDEKP 154
N +IKGRT+ VD KD++ + + + E E +E+
Sbjct: 173 GMNMKEIKGRTVAVDWAVAKDKYKDTQSVSAIGEEKSHESKHQESVKKKGREEEDMEEEE 232
Query: 155 TKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQ 214
D E+ ++++ + ++++ +++ VK HS ++S+ +
Sbjct: 233 NDDDDDDDDEEDGVFDDEDEEEENIESKVTKPVQIQKRAVKRPAPAKSSDHSEEDSDLEE 292
Query: 215 KSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKT 264
+G++L +S T+ E+E K + ++ K + E KT
Sbjct: 293 SDSIDDGEELAQSDTSTE------EQEDKAVQVSNKKKRKLPSDVNEGKT 336
Score = 40.0 bits (92), Expect = 0.003
Identities = 27/105 (25%), Positives = 50/105 (47%), Gaps = 6/105 (5%)
Query: 12 ELNEREVQLGVADKVSWHSEYKDSAWIFLGGLPYELTEGDIICVFSQYGEIVNINLVRDK 71
E ++ VQ+ K S+ + +F+ L ++ E ++ + Q+GE+ + +V
Sbjct: 311 EQEDKAVQVSNKKKRKLPSDVNEGKTVFIRNLSFDSEEEELGELLQQFGELKYVRIVLHP 370
Query: 72 KTGKSKGFC---FLCYEDQRSTILAVDNFN---GIKIKGRTIRVD 110
T SKG F+ E + +LA N G+K+ GR ++VD
Sbjct: 371 DTEHSKGCAFAQFMTQEAAQKCLLAASPENEAGGLKLDGRQLKVD 415
Score = 31.6 bits (70), Expect = 0.99
Identities = 32/135 (23%), Positives = 54/135 (40%), Gaps = 28/135 (20%)
Query: 38 IFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCY---EDQRSTILAV 94
+F+G LP + +FSQ G + +V +K + +GF ++ + ED + + +
Sbjct: 6 LFVGRLPPSARSEQLEELFSQVGPVKQCFVVTEKGSKACRGFGYVTFSMLEDVQRALKEI 65
Query: 95 DNFNGIKIKGRTIRVDHVSNYRAPKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKP 154
F G KI +VT + +K +T +E+SE K
Sbjct: 66 TTFEGCKI-----------------------NVT--VAKKKLRNKTKEKGKNENSECPKK 100
Query: 155 TKKHKKDKKEKKKKK 169
K KK K KK +
Sbjct: 101 EPKAKKAKVADKKAR 115
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 63.2 bits (152), Expect = 3e-10
Identities = 42/184 (22%), Positives = 89/184 (48%), Gaps = 20/184 (10%)
Query: 149 SEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPR-----RKTVKEKD---DT 200
++ E+ + + +KE++++K +E+ +RE Q E+ + + R R+ +E++ +T
Sbjct: 163 TDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETET 222
Query: 201 GPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAR 260
K+ + + +R +K+E ++ + R + D ERE ++++ + + RE +
Sbjct: 223 ERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQ 282
Query: 261 EEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSHRHKRAR---RSRERESSNPS 317
++ R R R + +E + R R R R++ KR R R RERE +
Sbjct: 283 TDRKRQRRTERDRE---------TERKRERQRERERERERNRKRERERERERERERQRET 333
Query: 318 DRWR 321
+R R
Sbjct: 334 ERDR 337
Score = 62.4 bits (150), Expect = 5e-10
Identities = 47/229 (20%), Positives = 96/229 (41%), Gaps = 14/229 (6%)
Query: 103 KGRTIRVDHVSNYRAPKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDK 162
K R + D + + K+ + R+ + +G R E ++ +K ++ +
Sbjct: 103 KERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQ 162
Query: 163 KEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQ 222
+++++++ + +E + E+ R+ +EK++ +HS + ER ++ E
Sbjct: 163 TDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERET---- 218
Query: 223 KLPKSRTAYSGGAEDLERELKKEKPKH-EHKSSSRREAREEKTRIRDRGRSSDAHSSWYN 281
+ R + D +R+ ++E+ K E + +S RE +K R R+R R D
Sbjct: 219 ETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKE 278
Query: 282 GRSEGRSYRSRSRSRDKSHRHKRAR---------RSRERESSNPSDRWR 321
+ R R RD+ KR R R+R+RE +R R
Sbjct: 279 RERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERER 327
Score = 62.0 bits (149), Expect = 7e-10
Identities = 51/206 (24%), Positives = 98/206 (47%), Gaps = 23/206 (11%)
Query: 116 RAPKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKA 175
+A KD++ D + +E+ R +E D K ++ +KD+ K+ + +E+++
Sbjct: 44 QAHKDADGDDRERNRQKER---ERRREKRQTERETDRKRERRREKDRHRKRDRHRERQR- 99
Query: 176 DREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGA 235
DRE + E R+T +E+ D +K ++ ER +++E REG+ + R + G
Sbjct: 100 DREKERE--------RQTDRER-DRQREKERNRQKERERETE-REGE---RGRDRQTDGQ 146
Query: 236 EDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRS 295
+ ER+ EK + E ++ R+ + E+ R ++R R + R E R +
Sbjct: 147 RERERQRDAEK-ERERQTDRERQRQTERNRQKEREREKNRQE-----RRERERQREKENK 200
Query: 296 RDKSHRHKRARRSRERESSNPSDRWR 321
+ H + R RERE+ ++R R
Sbjct: 201 TEDRHSERGRERERERETETETERKR 226
Score = 60.5 bits (145), Expect = 2e-09
Identities = 39/176 (22%), Positives = 88/176 (50%), Gaps = 10/176 (5%)
Query: 147 ESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHS 206
E D K ++ ++D++ ++K+++++E+ +RE + + R+ +E+ ++ +
Sbjct: 280 ERQTDRKRQRRTERDRETERKRERQRER-ERERERNRKRERERERERERER-----QRET 333
Query: 207 SKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTRI 266
++ E+ ++ + + ++ + R +G + E ++E+ + + S+R REE+ R
Sbjct: 334 ERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARE--REERERD 391
Query: 267 RDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSHRHKRAR-RSRERESSNPSDRWR 321
RDR R + R +G+ + R R+K +R R R RERE +R R
Sbjct: 392 RDRDRQKERERQTEKDR-DGQRETEKQREREKDRESERGRERGREREKQKGRERDR 446
Score = 58.9 bits (141), Expect = 6e-09
Identities = 39/192 (20%), Positives = 83/192 (43%), Gaps = 7/192 (3%)
Query: 133 EKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRK 192
E+G + +E+ + ++ + +K +++++K+ E+ +R + E R+
Sbjct: 207 ERGRERERERETETETERKRQTDRERDRQRKTEREREKQAER-ERASERETERDKERERE 265
Query: 193 TVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPK---- 248
+++D +K + ++R ++ ++ + R + ER K+E+ +
Sbjct: 266 RDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERER 325
Query: 249 -HEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSHRHKRARR 307
E + + R+ +E+ R R R D + GR EGR R R R++ + AR
Sbjct: 326 ERERQRETERDREKERERKRKRQTEMDRERNRQTGR-EGRRQAERERERERERDRQSARE 384
Query: 308 SRERESSNPSDR 319
ERE DR
Sbjct: 385 REERERDRDRDR 396
Score = 58.9 bits (141), Expect = 6e-09
Identities = 44/217 (20%), Positives = 102/217 (47%), Gaps = 16/217 (7%)
Query: 119 KDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKH-KKDKKEKKKKKKEKEKADR 177
+++E + RQ + R + +E E+ +++ ++DK+ ++++ +++++ R
Sbjct: 216 RETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRR 275
Query: 178 EVQAEQPSSSSPRRKTVKEKDDTGPKKHS---SKNSERAQKSEPREGQKLPKSRTAYSGG 234
+ + E+ + +R+T ++++ ++ + ER +K E ++ + R +
Sbjct: 276 QKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETER 335
Query: 235 AEDLERELKKEKPKHEHKSSSR---REAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRS 291
+ ERE K+++ + +R RE R + R R+R R D S+ R E R
Sbjct: 336 DREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSA--REREERERDRD 393
Query: 292 RSRSRDKSHRHKRAR-------RSRERESSNPSDRWR 321
R R +++ + ++ R + RERE S+R R
Sbjct: 394 RDRQKERERQTEKDRDGQRETEKQREREKDRESERGR 430
Score = 55.8 bits (133), Expect = 5e-08
Identities = 40/185 (21%), Positives = 83/185 (44%), Gaps = 3/185 (1%)
Query: 103 KGRTIRVDHVSNYRAPKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDK 162
K R + D R +D E RQ + + R E E+ ++ +
Sbjct: 277 KERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERD 336
Query: 163 KEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKD-DTGPKKHSSKNSERAQKSEPREG 221
+EK++++K K + + + + + + RR+ +E++ + + S++ E ++ R+
Sbjct: 337 REKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDR 396
Query: 222 QKLPKSRTAYS-GGAEDLERELKKEKPKHEHKSSSR-REAREEKTRIRDRGRSSDAHSSW 279
QK + +T G + E++ ++EK + + R RE ++K R RDR R +D +
Sbjct: 397 QKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGR 456
Query: 280 YNGRS 284
RS
Sbjct: 457 QRKRS 461
Score = 55.5 bits (132), Expect = 6e-08
Identities = 49/212 (23%), Positives = 96/212 (45%), Gaps = 23/212 (10%)
Query: 116 RAPKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEK- 174
R K+ E D RQ RT +E + + ++ ++++ K+++++E+E+
Sbjct: 274 RRQKERERQTDRKRQ-------RRTERDRETERKRERQRERERERERNRKRERERERERE 326
Query: 175 --ADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYS 232
RE + ++ +RK E D ++ + +A++ RE ++ +S
Sbjct: 327 RERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARERE 386
Query: 233 GGAEDLERELKKEKPKHEHKS-SSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRS-YR 290
D +R+ +KE+ + K +RE EK R R++ R S+ GR GR +
Sbjct: 387 ERERDRDRDRQKERERQTEKDRDGQRET--EKQREREKDRESE------RGRERGREREK 438
Query: 291 SRSRSRDKSHR-HKRARRSRERES--SNPSDR 319
+ R RD+ + ++A R R+R + NP R
Sbjct: 439 QKGRERDRERQTDRQAGRQRKRSTLYVNPPPR 470
Score = 54.7 bits (130), Expect = 1e-07
Identities = 37/178 (20%), Positives = 83/178 (46%), Gaps = 8/178 (4%)
Query: 143 PSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGP 202
P ES + HK + +++ ++KE+ R + + + +R+ +EKD
Sbjct: 31 PGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRK 90
Query: 203 K-KHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPK-HEHKSSSRREAR 260
+ +H + +R ++ E + ++ + R ++ ERE ++E + + ++ +RE
Sbjct: 91 RDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERE 150
Query: 261 EEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSHRHKRARRSRERESSNPSD 318
++ ++R R +D R+ R + R R+K +R +R R R+RE N ++
Sbjct: 151 RQRDAEKERERQTDRERQRQTERN-----RQKEREREK-NRQERRERERQREKENKTE 202
Score = 49.3 bits (116), Expect = 5e-06
Identities = 39/146 (26%), Positives = 63/146 (43%), Gaps = 20/146 (13%)
Query: 185 SSSSPRRKTVKE--KDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLEREL 242
S SPRR+ + + KD G + ++ ER ++ E R+ ++ D +RE
Sbjct: 33 SQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTER-----------ETDRKRER 81
Query: 243 KKEKPKHEHKSSSRREARE-EKTRIRDRGRSSDAHSSWYNGRSEGR---SYRSRSRSRDK 298
++EK +H + R R+ EK R R R D R + R + R R RD+
Sbjct: 82 RREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDR 141
Query: 299 ---SHRHKRARRSRERESSNPSDRWR 321
R + +R E+E +DR R
Sbjct: 142 QTDGQRERERQRDAEKERERQTDRER 167
>gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens]
Length = 405
Score = 62.4 bits (150), Expect = 5e-10
Identities = 27/76 (35%), Positives = 48/76 (63%)
Query: 38 IFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNF 97
+++G L + +TE + +F +G+I NI L++D TG+SKG+ F+ + D A++
Sbjct: 231 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 290
Query: 98 NGIKIKGRTIRVDHVS 113
NG ++ GR +RV HV+
Sbjct: 291 NGFELAGRPMRVGHVT 306
Score = 37.0 bits (84), Expect = 0.024
Identities = 28/85 (32%), Positives = 36/85 (42%), Gaps = 11/85 (12%)
Query: 236 EDLERELKKEKPKHEHKSSSRREAR--------EEKTRIRDRGRSSDAHSSWYNGRSEGR 287
E +E+KK+ P + S+S E R RDR R +S RS GR
Sbjct: 24 EQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSNRSRDRDRYRRRNS---RSRSPGR 80
Query: 288 SYRSRSRSRDKSHRHKRARRSRERE 312
R RSRS D+ H + R RE
Sbjct: 81 QCRHRSRSWDRRHGSESRSRDHRRE 105
Score = 31.6 bits (70), Expect = 0.99
Identities = 15/64 (23%), Positives = 35/64 (54%)
Query: 31 EYKDSAWIFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRST 90
E +D+ +F L + D+ FS G++ ++ ++ D+ + +SKG ++ + + +S
Sbjct: 127 EERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSV 186
Query: 91 ILAV 94
LA+
Sbjct: 187 PLAI 190
Score = 31.2 bits (69), Expect = 1.3
Identities = 27/104 (25%), Positives = 47/104 (45%), Gaps = 7/104 (6%)
Query: 164 EKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQK 223
E KK+E E+ +EV+ + PS++ T + SS E + +S R+ +
Sbjct: 15 EAPYKKEEDEQQRKEVKKDYPSNT-----TSSTSNSGNETSGSSTIGETSNRSRDRDRYR 69
Query: 224 LPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTRIR 267
SR+ S G + R ++ +H +S SR RE++ R
Sbjct: 70 RRNSRSR-SPGRQCRHRSRSWDR-RHGSESRSRDHRREDRVHYR 111
>gi|116734696 RNA binding motif protein 23 isoform 1 [Homo sapiens]
Length = 439
Score = 62.4 bits (150), Expect = 5e-10
Identities = 27/76 (35%), Positives = 48/76 (63%)
Query: 38 IFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNF 97
+++G L + +TE + +F +G+I NI L++D TG+SKG+ F+ + D A++
Sbjct: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324
Query: 98 NGIKIKGRTIRVDHVS 113
NG ++ GR +RV HV+
Sbjct: 325 NGFELAGRPMRVGHVT 340
Score = 43.9 bits (102), Expect = 2e-04
Identities = 33/112 (29%), Positives = 53/112 (47%), Gaps = 12/112 (10%)
Query: 205 HSSKNSERAQKSEPREGQKLPKSRTAYSG----GAEDLERELKKEKPKHEHKSSSRREAR 260
+ + E+ +K ++ S T+ SG G+ + KK++ + +KS R+ +R
Sbjct: 18 YKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSKKKRSRSHNKSRDRKRSR 77
Query: 261 EEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSHRHKRARRSRERE 312
+R RDR R ++ S RS GR R RSRS D+ H + R RE
Sbjct: 78 ---SRDRDRYRRRNSRS-----RSPGRQCRHRSRSWDRRHGSESRSRDHRRE 121
Score = 39.3 bits (90), Expect = 0.005
Identities = 27/151 (17%), Positives = 63/151 (41%), Gaps = 2/151 (1%)
Query: 115 YRAPKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEK 174
Y+ +D ++ +V + + + S + + S T K K+ + K + +++ +
Sbjct: 18 YKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSKKKRSRSHNKSRDRKRSR 77
Query: 175 A-DREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSG 233
+ DR+ + S S + + + + ++H S++ R + E R + P T Y
Sbjct: 78 SRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSPPLATGYRY 137
Query: 234 GAEDLERELKKEKPKHEHKSSSRREAREEKT 264
G +++ P E + E R+ +T
Sbjct: 138 G-HSKSPHFREKSPVREPVDNLSPEERDART 167
Score = 35.0 bits (79), Expect = 0.090
Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
Query: 236 EDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRS 295
E +E+KK+ P + S+S + E + G +S S + +S R RSRSR
Sbjct: 24 EQQRKEVKKDYPSNTTSSTSN--SGNETSGSSTIGETSKKKRSRSHNKSRDRK-RSRSRD 80
Query: 296 RDKSHRHKRARRSRERESSNPSDRW 320
RD+ R RS R+ + S W
Sbjct: 81 RDRYRRRNSRSRSPGRQCRHRSRSW 105
Score = 31.6 bits (70), Expect = 0.99
Identities = 15/64 (23%), Positives = 35/64 (54%)
Query: 31 EYKDSAWIFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRST 90
E +D+ +F L + D+ FS G++ ++ ++ D+ + +SKG ++ + + +S
Sbjct: 161 EERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSV 220
Query: 91 ILAV 94
LA+
Sbjct: 221 PLAI 224
>gi|116734694 RNA binding motif protein 23 isoform 2 [Homo sapiens]
Length = 423
Score = 62.4 bits (150), Expect = 5e-10
Identities = 27/76 (35%), Positives = 48/76 (63%)
Query: 38 IFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNF 97
+++G L + +TE + +F +G+I NI L++D TG+SKG+ F+ + D A++
Sbjct: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308
Query: 98 NGIKIKGRTIRVDHVS 113
NG ++ GR +RV HV+
Sbjct: 309 NGFELAGRPMRVGHVT 324
Score = 37.0 bits (84), Expect = 0.024
Identities = 28/85 (32%), Positives = 36/85 (42%), Gaps = 11/85 (12%)
Query: 236 EDLERELKKEKPKHEHKSSSRREAR--------EEKTRIRDRGRSSDAHSSWYNGRSEGR 287
E +E+KK+ P + S+S E R RDR R +S RS GR
Sbjct: 24 EQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSNRSRDRDRYRRRNS---RSRSPGR 80
Query: 288 SYRSRSRSRDKSHRHKRARRSRERE 312
R RSRS D+ H + R RE
Sbjct: 81 QCRHRSRSWDRRHGSESRSRDHRRE 105
Score = 34.7 bits (78), Expect = 0.12
Identities = 29/134 (21%), Positives = 55/134 (41%), Gaps = 11/134 (8%)
Query: 164 EKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQK 223
E KK+E E+ +EV+ + PS++ T + SS E + +S R+ +
Sbjct: 15 EAPYKKEEDEQQRKEVKKDYPSNT-----TSSTSNSGNETSGSSTIGETSNRSRDRDRYR 69
Query: 224 LPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGR 283
SR+ G R+ + + + S +R+ + R RS + + G
Sbjct: 70 RRNSRSRSPG------RQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSPPLATGYRYGH 123
Query: 284 SEGRSYRSRSRSRD 297
S+ +R +S R+
Sbjct: 124 SKSPHFREKSPVRE 137
Score = 31.6 bits (70), Expect = 0.99
Identities = 15/64 (23%), Positives = 35/64 (54%)
Query: 31 EYKDSAWIFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRST 90
E +D+ +F L + D+ FS G++ ++ ++ D+ + +SKG ++ + + +S
Sbjct: 145 EERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSV 204
Query: 91 ILAV 94
LA+
Sbjct: 205 PLAI 208
>gi|9558733 transformer-2 alpha [Homo sapiens]
Length = 282
Score = 61.6 bits (148), Expect = 9e-10
Identities = 31/76 (40%), Positives = 49/76 (64%)
Query: 42 GLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNFNGIK 101
GL TE D+ VFS+YG + +N+V D++TG+S+GF F+ +E + A++ NG++
Sbjct: 125 GLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGME 184
Query: 102 IKGRTIRVDHVSNYRA 117
+ GR IRVD+ RA
Sbjct: 185 LDGRRIRVDYSITKRA 200
Score = 37.4 bits (85), Expect = 0.018
Identities = 41/133 (30%), Positives = 52/133 (39%), Gaps = 32/133 (24%)
Query: 194 VKEKDDTGPKKHSSKNSERAQ----KSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKH 249
V+E + G + S S KSE R G + P SR + KH
Sbjct: 4 VEENNFEGRESRSQSKSPTGTPARVKSESRSGSRSP-SRVS-----------------KH 45
Query: 250 EHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSHRHKRARRSR 309
S R K+R R R S H + RS S+R RSRSR + + RR R
Sbjct: 46 SESHSRSR----SKSRSRSRRHS---HRRYTRSRSHSHSHRRRSRSRSYTPEY---RRRR 95
Query: 310 ERESSNPSDRWRH 322
R S S+R RH
Sbjct: 96 SRSHSPMSNRRRH 108
>gi|56699409 RNA binding motif protein, X-linked [Homo sapiens]
Length = 391
Score = 61.6 bits (148), Expect = 9e-10
Identities = 72/282 (25%), Positives = 103/282 (36%), Gaps = 38/282 (13%)
Query: 38 IFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNF 97
+F+GGL E E + VF +YG IV + L++D++T KS+GF F+ +E A +
Sbjct: 10 LFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDM 69
Query: 98 NGIKIKGRTIRVDHV------SNYRAPKDSEEIDDVTRQLQ--EKGCGARTPSPSLSESS 149
NG + G+ I+V+ S R P R L+ G G PS
Sbjct: 70 NGKSLDGKAIKVEQATKPSFESGRRGPPPPPRSRGPPRGLRGGRGGSGGTRGPPSRGGHM 129
Query: 150 EDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKN 209
+D + K + P S P K +GP + SS
Sbjct: 130 DDGGYSMNFNMSSSRGPLPVK---------RGPPPRSGGP---PPKRSAPSGPVRSSSGM 177
Query: 210 SERAQKSEPREG-------QKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREARE- 261
RA S R+ + LP R Y +D K ++ SS R+ R+
Sbjct: 178 GGRAPVSRGRDSYGGPPRREPLPSRRDVYLSPRDD-GYSTKDSYSSRDYPSS--RDTRDY 234
Query: 262 ----EKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKS 299
RD G SS G S+ Y R RD S
Sbjct: 235 APPPRDYTYRDYGHSSSRDDYPSRGYSDRDGY---GRDRDYS 273
>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
Length = 450
Score = 61.2 bits (147), Expect = 1e-09
Identities = 59/197 (29%), Positives = 80/197 (40%), Gaps = 26/197 (13%)
Query: 151 DEKPTKKHKKDKKEKK-KKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKN 209
D KK KKD+K+KK +K + K K + + SSSS E + K
Sbjct: 229 DRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKK 288
Query: 210 SERAQK----------SEPREGQKLPKSRTAYSGGAEDLERELKKEKP---KHEHK---- 252
+R ++ S+ E K K + + RE KEKP KHE
Sbjct: 289 IQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDS 348
Query: 253 ----SSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSR---SRDKSHRHKRA 305
S S +++R K RG SS +GR E RS RSRSR S + KRA
Sbjct: 349 KWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREE-RSRRSRSRSPGSYKQRETRKRA 407
Query: 306 RRSRERESSNPSDRWRH 322
+R+ E S +D H
Sbjct: 408 QRNPGEEQSRRNDSRSH 424
Score = 60.8 bits (146), Expect = 2e-09
Identities = 46/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Query: 148 SSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSS 207
+ + +K +K + +K+KKKK ++K+K + + SS + + SS
Sbjct: 218 TKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESS 277
Query: 208 KNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSS--RREAREEKTR 265
SE K + + +K K++ + ++ E++ K++ HE SSS RE +EK R
Sbjct: 278 SESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPR 337
Query: 266 IRDRGRSSDAHSSWYNGRSEGRS--------YRSRSRSRDKSHRHKRARRSRERESSNP 316
+ SS S W + S+ +S R R S H R RSR S +P
Sbjct: 338 FL-KHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSP 395
Score = 45.4 bits (106), Expect = 7e-05
Identities = 52/181 (28%), Positives = 72/181 (39%), Gaps = 47/181 (25%)
Query: 142 SPSLSESSEDEKPT--KKHKKDK--KEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEK 197
S S SES+ EK KK KK+K +EK+K+ + E+ SSS R+ KEK
Sbjct: 276 SSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEK 335
Query: 198 DDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRR 257
P+ ++S K + K KSRT H+H R
Sbjct: 336 ----PRFLKHESSREDSKWSHSDSDK--KSRT-------------------HKHSPEKRG 370
Query: 258 EAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSHRHKRARRSRERESSNPS 317
R+E + RS GR RSR RSR +S + R +R+R NP
Sbjct: 371 SERKEG-----------------SSRSHGREERSR-RSRSRSPGSYKQRETRKRAQRNPG 412
Query: 318 D 318
+
Sbjct: 413 E 413
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.125 0.354
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,483,118
Number of Sequences: 37866
Number of extensions: 689184
Number of successful extensions: 22749
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 876
Number of HSP's successfully gapped in prelim test: 973
Number of HSP's that attempted gapping in prelim test: 6934
Number of HSP's gapped (non-prelim): 8010
length of query: 322
length of database: 18,247,518
effective HSP length: 102
effective length of query: 220
effective length of database: 14,385,186
effective search space: 3164740920
effective search space used: 3164740920
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.