Guide to the Human Genome
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Name: PFKFB1 Sequence: fasta or formatted (471aa) NCBI GI: 118582286
Description:

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

Referenced in:

Glycolysis

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.1         24           2
 C cysteine            2.1         10           1
 D aspartate           4.5         21           1
 E glutamate           9.1         43           2
 F phenylalanine       2.8         13           2
 G glycine             4.9         23           2
 H histidine           3.2         15           1
 I isoleucine          6.6         31           2
 K lysine              5.1         24           1
 L leucine             9.1         43           2
 M methionine          2.3         11           1
 N asparagine          4.0         19           1
 P proline             4.5         21           1
 Q glutamine           4.7         22           1
 R arginine            7.0         33           3
 S serine              6.2         29           2
 T threonine           5.1         24           2
 V valine              6.8         32           1
 W tryptophan          0.8          4           1
 Y tyrosine            6.2         29           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase... 
PFKFB4                0.749   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4...
PFKFB3                0.689   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3...
PFKFB3                0.672   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase...
PFKFB2                0.671   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase ...
PFKFB2                0.670   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase ...
C14orf174             0.013   hypothetical protein LOC161394 
ARF6                  0.010   ADP-ribosylation factor 6 
SCN3A                 0.009   sodium channel, voltage-gated, type III, alpha isof...
PGAM1                 0.009   bisphosphoglycerate mutase 1 
GPN1                  0.007   GPN-loop GTPase 1 isoform a 
MRRF                  0.007   mitochondrial ribosome recycling factor isoform 1 [H...
PRSS35                0.007   protease, serine, 35 
ARF1                  0.006   ADP-ribosylation factor 1 
ARF1                  0.006   ADP-ribosylation factor 1 
ARF1                  0.006   ADP-ribosylation factor 1 
ARF1                  0.006   ADP-ribosylation factor 1 
PGAM2                 0.006   bisphosphoglycerate mutase 2 
ARF3                  0.006   ADP-ribosylation factor 3 
ARF5                  0.005   ADP-ribosylation factor 5 
LOC100131531          0.005   PREDICTED: similar to hCG1644658 
LOC100131531          0.005   PREDICTED: similar to hCG1644658 
LOC100287833          0.005   PREDICTED: hypothetical protein XP_002342587 
CNP                   0.004   2',3'-cyclic nucleotide 3' phosphodiesterase 
ERC2                  0.004   cytomatrix protein p110 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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