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Search of human proteins with 117938750
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|117938750 constitutive androstane receptor isoform 10 [Homo
sapiens]
(319 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|117938750 constitutive androstane receptor isoform 10 [Homo s... 638 0.0
gi|117938736 constitutive androstane receptor isoform 9 [Homo sa... 632 0.0
gi|4826661 constitutive androstane receptor isoform 3 [Homo sapi... 626 e-180
gi|117938752 constitutive androstane receptor isoform 2 [Homo sa... 620 e-178
gi|117938756 constitutive androstane receptor isoform 1 [Homo sa... 614 e-176
gi|117938748 constitutive androstane receptor isoform 14 [Homo s... 557 e-159
gi|117938744 constitutive androstane receptor isoform 13 [Homo s... 551 e-157
gi|117938738 constitutive androstane receptor isoform 12 [Homo s... 545 e-155
gi|117938732 constitutive androstane receptor isoform 11 [Homo s... 542 e-154
gi|117938746 constitutive androstane receptor isoform 7 [Homo sa... 540 e-154
gi|117938729 constitutive androstane receptor isoform 6 [Homo sa... 539 e-153
gi|117938754 constitutive androstane receptor isoform 4 [Homo sa... 533 e-152
gi|117938734 constitutive androstane receptor isoform 5 [Homo sa... 531 e-151
gi|117938742 constitutive androstane receptor isoform 15 [Homo s... 461 e-130
gi|117938740 constitutive androstane receptor isoform 8 [Homo sa... 450 e-127
gi|14702164 nuclear receptor subfamily 1, group I, member 2 isof... 248 7e-66
gi|11863132 nuclear receptor subfamily 1, group I, member 2 isof... 236 2e-62
gi|34398348 nuclear receptor subfamily 1, group I, member 2 isof... 236 2e-62
gi|194294519 nuclear receptor subfamily 1, group H, member 3 iso... 141 7e-34
gi|194294517 nuclear receptor subfamily 1, group H, member 3 iso... 141 7e-34
gi|63054845 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo ... 130 1e-30
gi|4507883 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo s... 130 1e-30
gi|85362735 nuclear receptor subfamily 1, group H, member 2 [Hom... 125 5e-29
gi|189491771 thyroid hormone receptor, beta [Homo sapiens] 118 8e-27
gi|189491769 thyroid hormone receptor, beta [Homo sapiens] 118 8e-27
gi|40806162 thyroid hormone receptor, beta [Homo sapiens] 118 8e-27
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 112 4e-25
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens] 112 4e-25
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 112 4e-25
gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens] 111 1e-24
>gi|117938750 constitutive androstane receptor isoform 10 [Homo
sapiens]
Length = 319
Score = 638 bits (1645), Expect = 0.0
Identities = 319/319 (100%), Positives = 319/319 (100%)
Query: 1 MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1 MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
Query: 61 RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61 RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
Query: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240
FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240
Query: 241 PDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQ 300
PDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQ
Sbjct: 241 PDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQ 300
Query: 301 IQHIQGLSAMMPLLQEICS 319
IQHIQGLSAMMPLLQEICS
Sbjct: 301 IQHIQGLSAMMPLLQEICS 319
>gi|117938736 constitutive androstane receptor isoform 9 [Homo
sapiens]
Length = 324
Score = 632 bits (1629), Expect = 0.0
Identities = 319/324 (98%), Positives = 319/324 (98%), Gaps = 5/324 (1%)
Query: 1 MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1 MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
Query: 61 RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61 RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
Query: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240
FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240
Query: 241 P-----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINE 295
P DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINE
Sbjct: 241 PAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINE 300
Query: 296 AYGYQIQHIQGLSAMMPLLQEICS 319
AYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 301 AYGYQIQHIQGLSAMMPLLQEICS 324
>gi|4826661 constitutive androstane receptor isoform 3 [Homo
sapiens]
Length = 348
Score = 626 bits (1615), Expect = e-180
Identities = 313/313 (100%), Positives = 313/313 (100%)
Query: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
Query: 67 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
Query: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGV 246
NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGV
Sbjct: 216 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGV 275
Query: 247 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQG 306
TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQG
Sbjct: 276 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQG 335
Query: 307 LSAMMPLLQEICS 319
LSAMMPLLQEICS
Sbjct: 336 LSAMMPLLQEICS 348
>gi|117938752 constitutive androstane receptor isoform 2 [Homo
sapiens]
Length = 352
Score = 620 bits (1600), Expect = e-178
Identities = 313/317 (98%), Positives = 313/317 (98%), Gaps = 4/317 (1%)
Query: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
Query: 67 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
Query: 187 NFLCGPLRYTIEDGAR----VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD 242
NFLCGPLRYTIEDGAR VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD
Sbjct: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD 275
Query: 243 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQ 302
RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQ
Sbjct: 276 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQ 335
Query: 303 HIQGLSAMMPLLQEICS 319
HIQGLSAMMPLLQEICS
Sbjct: 336 HIQGLSAMMPLLQEICS 352
>gi|117938756 constitutive androstane receptor isoform 1 [Homo
sapiens]
Length = 357
Score = 614 bits (1584), Expect = e-176
Identities = 313/322 (97%), Positives = 313/322 (97%), Gaps = 9/322 (2%)
Query: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
Query: 67 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
Query: 187 NFLCGPLRYTIEDGAR----VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP- 241
NFLCGPLRYTIEDGAR VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP
Sbjct: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 275
Query: 242 ----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAY 297
DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAY
Sbjct: 276 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAY 335
Query: 298 GYQIQHIQGLSAMMPLLQEICS 319
GYQIQHIQGLSAMMPLLQEICS
Sbjct: 336 GYQIQHIQGLSAMMPLLQEICS 357
>gi|117938748 constitutive androstane receptor isoform 14 [Homo
sapiens]
Length = 306
Score = 557 bits (1435), Expect = e-159
Identities = 277/277 (100%), Positives = 277/277 (100%)
Query: 1 MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1 MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
Query: 61 RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61 RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
Query: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240
FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240
Query: 241 PDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277
PDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 241 PDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277
>gi|117938744 constitutive androstane receptor isoform 13 [Homo
sapiens]
Length = 311
Score = 551 bits (1419), Expect = e-157
Identities = 277/282 (98%), Positives = 277/282 (98%), Gaps = 5/282 (1%)
Query: 1 MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1 MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
Query: 61 RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61 RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
Query: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240
FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240
Query: 241 P-----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277
P DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 241 PAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 282
>gi|117938738 constitutive androstane receptor isoform 12 [Homo
sapiens]
Length = 315
Score = 545 bits (1404), Expect = e-155
Identities = 277/286 (96%), Positives = 277/286 (96%), Gaps = 9/286 (3%)
Query: 1 MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1 MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
Query: 61 RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61 RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
Query: 181 FCLQTQNFLCGPLRYTIEDGAR----VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAM 236
FCLQTQNFLCGPLRYTIEDGAR VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAM
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAM 240
Query: 237 ALFSP-----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277
ALFSP DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 241 ALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 286
>gi|117938732 constitutive androstane receptor isoform 11 [Homo
sapiens]
Length = 280
Score = 542 bits (1397), Expect = e-154
Identities = 280/319 (87%), Positives = 280/319 (87%), Gaps = 39/319 (12%)
Query: 1 MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1 MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
Query: 61 RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61 RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
Query: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240
FCLQTQNFLCGPLRYTIEDGAR
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGAR-------------------------------------- 202
Query: 241 PDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQ 300
DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQ
Sbjct: 203 -DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQ 261
Query: 301 IQHIQGLSAMMPLLQEICS 319
IQHIQGLSAMMPLLQEICS
Sbjct: 262 IQHIQGLSAMMPLLQEICS 280
>gi|117938746 constitutive androstane receptor isoform 7 [Homo
sapiens]
Length = 339
Score = 540 bits (1390), Expect = e-154
Identities = 271/275 (98%), Positives = 271/275 (98%), Gaps = 4/275 (1%)
Query: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
Query: 67 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
Query: 187 NFLCGPLRYTIEDGAR----VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD 242
NFLCGPLRYTIEDGAR VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD
Sbjct: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD 275
Query: 243 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277
RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 276 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 310
>gi|117938729 constitutive androstane receptor isoform 6 [Homo
sapiens]
Length = 340
Score = 539 bits (1389), Expect = e-153
Identities = 271/276 (98%), Positives = 271/276 (98%), Gaps = 5/276 (1%)
Query: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
Query: 67 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
Query: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP----- 241
NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP
Sbjct: 216 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLT 275
Query: 242 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277
DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 276 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 311
>gi|117938754 constitutive androstane receptor isoform 4 [Homo
sapiens]
Length = 314
Score = 533 bits (1373), Expect = e-152
Identities = 275/313 (87%), Positives = 276/313 (88%), Gaps = 34/313 (10%)
Query: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
Query: 67 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
Query: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGV 246
NFLCGPLRYTIEDGAR A + DRPGV
Sbjct: 216 NFLCGPLRYTIEDGAR----------------------------------APYLTDRPGV 241
Query: 247 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQG 306
TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQG
Sbjct: 242 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQG 301
Query: 307 LSAMMPLLQEICS 319
LSAMMPLLQEICS
Sbjct: 302 LSAMMPLLQEICS 314
>gi|117938734 constitutive androstane receptor isoform 5 [Homo
sapiens]
Length = 309
Score = 531 bits (1367), Expect = e-151
Identities = 274/313 (87%), Positives = 274/313 (87%), Gaps = 39/313 (12%)
Query: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
Query: 67 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
Query: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGV 246
NFLCGPLRYTIEDGAR DRPGV
Sbjct: 216 NFLCGPLRYTIEDGAR---------------------------------------DRPGV 236
Query: 247 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQG 306
TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQG
Sbjct: 237 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQG 296
Query: 307 LSAMMPLLQEICS 319
LSAMMPLLQEICS
Sbjct: 297 LSAMMPLLQEICS 309
>gi|117938742 constitutive androstane receptor isoform 15 [Homo
sapiens]
Length = 267
Score = 461 bits (1187), Expect = e-130
Identities = 238/277 (85%), Positives = 238/277 (85%), Gaps = 39/277 (14%)
Query: 1 MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1 MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
Query: 61 RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61 RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
Query: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240
FCLQTQNFLCGPLRYTIEDGAR
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGAR-------------------------------------- 202
Query: 241 PDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277
DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 203 -DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238
>gi|117938740 constitutive androstane receptor isoform 8 [Homo
sapiens]
Length = 296
Score = 450 bits (1157), Expect = e-127
Identities = 232/271 (85%), Positives = 232/271 (85%), Gaps = 39/271 (14%)
Query: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
Query: 67 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
Query: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGV 246
NFLCGPLRYTIEDGAR DRPGV
Sbjct: 216 NFLCGPLRYTIEDGAR---------------------------------------DRPGV 236
Query: 247 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277
TQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 237 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 267
>gi|14702164 nuclear receptor subfamily 1, group I, member 2 isoform
3 [Homo sapiens]
Length = 397
Score = 248 bits (632), Expect = 7e-66
Identities = 140/327 (42%), Positives = 200/327 (61%), Gaps = 17/327 (5%)
Query: 7 RRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQ 65
RR + ++ CPF G+CE+++ RR C ACRL+KCL++GM+K+MI+S EA+ RRA
Sbjct: 66 RRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALI 125
Query: 66 AQRRAQQTPVQ------LSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPL 119
++++++T Q L++EQ +IR L+ A + T F F FR L +
Sbjct: 126 KRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRVSLQLRGEDGSV 185
Query: 120 PTLAP--------VLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVE 171
P + L+ H AD++T+M +I F K + FR LPIEDQISLLKGAA E
Sbjct: 186 WNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFE 245
Query: 172 ICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYV 231
+C + NT F +T + CG L Y +ED A GFQ LE + FH L+KLQL E EYV
Sbjct: 246 LCQLRFNTVFNAETGTWECGRLSYCLEDTAG-GFQQLLLEPMLKFHYMLKKLQLHEEEYV 304
Query: 232 LLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELR 291
L+ A++LFSPDRPGV Q +DQLQE+ A+TL+SYI+ + +P RFL+ K++ +L ELR
Sbjct: 305 LMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELR 364
Query: 292 SINEAYGYQIQHIQGLSAM-MPLLQEI 317
SIN + ++ IQ + PL+QE+
Sbjct: 365 SINAQHTQRLLRIQDIHPFATPLMQEL 391
>gi|11863132 nuclear receptor subfamily 1, group I, member 2 isoform
2 [Homo sapiens]
Length = 473
Score = 236 bits (602), Expect = 2e-62
Identities = 143/364 (39%), Positives = 203/364 (55%), Gaps = 54/364 (14%)
Query: 7 RRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQ 65
RR + ++ CPF G+CE+++ RR C ACRL+KCL++GM+K+MI+S EA+ RRA
Sbjct: 105 RRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALI 164
Query: 66 AQRRAQQTPVQ------LSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQ-P 118
++++++T Q L++EQ +IR L+ A + T F F FR P L + P
Sbjct: 165 KRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGCELP 224
Query: 119 LPTLAP--------------------------------------------VLPLVTHFAD 134
AP + L+ H AD
Sbjct: 225 ESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMAD 284
Query: 135 INTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLR 194
++T+M +I F K + FR LPIEDQISLLKGAA E+C + NT F +T + CG L
Sbjct: 285 MSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLS 344
Query: 195 YTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQ 254
Y +ED A GFQ LE + FH L+KLQL E EYVL+ A++LFSPDRPGV Q +DQ
Sbjct: 345 YCLEDTAG-GFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQ 403
Query: 255 LQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAM-MPL 313
LQE+ A+TL+SYI+ + +P RFL+ K++ +L ELRSIN + ++ IQ + PL
Sbjct: 404 LQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPFATPL 463
Query: 314 LQEI 317
+QE+
Sbjct: 464 MQEL 467
>gi|34398348 nuclear receptor subfamily 1, group I, member 2 isoform
1 [Homo sapiens]
Length = 434
Score = 236 bits (602), Expect = 2e-62
Identities = 143/364 (39%), Positives = 203/364 (55%), Gaps = 54/364 (14%)
Query: 7 RRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQ 65
RR + ++ CPF G+CE+++ RR C ACRL+KCL++GM+K+MI+S EA+ RRA
Sbjct: 66 RRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALI 125
Query: 66 AQRRAQQTPVQ------LSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQ-P 118
++++++T Q L++EQ +IR L+ A + T F F FR P L + P
Sbjct: 126 KRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGCELP 185
Query: 119 LPTLAP--------------------------------------------VLPLVTHFAD 134
AP + L+ H AD
Sbjct: 186 ESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMAD 245
Query: 135 INTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLR 194
++T+M +I F K + FR LPIEDQISLLKGAA E+C + NT F +T + CG L
Sbjct: 246 MSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLS 305
Query: 195 YTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQ 254
Y +ED A GFQ LE + FH L+KLQL E EYVL+ A++LFSPDRPGV Q +DQ
Sbjct: 306 YCLEDTAG-GFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQ 364
Query: 255 LQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAM-MPL 313
LQE+ A+TL+SYI+ + +P RFL+ K++ +L ELRSIN + ++ IQ + PL
Sbjct: 365 LQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPFATPL 424
Query: 314 LQEI 317
+QE+
Sbjct: 425 MQEL 428
>gi|194294519 nuclear receptor subfamily 1, group H, member 3
isoform c [Homo sapiens]
Length = 402
Score = 141 bits (356), Expect = 7e-34
Identities = 98/327 (29%), Positives = 159/327 (48%), Gaps = 23/327 (7%)
Query: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
RR+V K C G C + RR C CRL+KC AGMR++ +LS E + L++ K+
Sbjct: 78 RRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQ 137
Query: 67 QR----------RAQQTPV---QLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRP-PAHL 112
+ RA P QLS EQ +I L+ A + F ++ P P
Sbjct: 138 EEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAP 197
Query: 113 FIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEI 172
H + HF ++ V +++ F K LP F L EDQI+LLK +A+E+
Sbjct: 198 DPHSREARQQR-----FAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEV 252
Query: 173 CHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYV 231
+ + + +++ Y ED A+ G QVEF+ +F F + +LQL + E+
Sbjct: 253 MLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFA 312
Query: 232 LLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELR 291
LL A+++FS DRP V + ++++LQ L +Y+ P DR ++ ++L L LR
Sbjct: 313 LLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYV--SIHHPHDRLMFPRMLMKLVSLR 370
Query: 292 SINEAYGYQIQHIQGLSAMM-PLLQEI 317
+++ + Q+ ++ + PLL EI
Sbjct: 371 TLSSVHSEQVFALRLQDKKLPPLLSEI 397
>gi|194294517 nuclear receptor subfamily 1, group H, member 3
isoform a [Homo sapiens]
Length = 447
Score = 141 bits (356), Expect = 7e-34
Identities = 98/327 (29%), Positives = 159/327 (48%), Gaps = 23/327 (7%)
Query: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
RR+V K C G C + RR C CRL+KC AGMR++ +LS E + L++ K+
Sbjct: 123 RRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQ 182
Query: 67 QR----------RAQQTPV---QLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRP-PAHL 112
+ RA P QLS EQ +I L+ A + F ++ P P
Sbjct: 183 EEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAP 242
Query: 113 FIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEI 172
H + HF ++ V +++ F K LP F L EDQI+LLK +A+E+
Sbjct: 243 DPHSREARQQR-----FAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEV 297
Query: 173 CHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYV 231
+ + + +++ Y ED A+ G QVEF+ +F F + +LQL + E+
Sbjct: 298 MLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFA 357
Query: 232 LLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELR 291
LL A+++FS DRP V + ++++LQ L +Y+ P DR ++ ++L L LR
Sbjct: 358 LLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYV--SIHHPHDRLMFPRMLMKLVSLR 415
Query: 292 SINEAYGYQIQHIQGLSAMM-PLLQEI 317
+++ + Q+ ++ + PLL EI
Sbjct: 416 TLSSVHSEQVFALRLQDKKLPPLLSEI 442
>gi|63054845 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo
sapiens]
Length = 427
Score = 130 bits (328), Expect = 1e-30
Identities = 69/177 (38%), Positives = 107/177 (60%), Gaps = 2/177 (1%)
Query: 126 LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQT 185
L ++ H AD+ ++ + +VI F K +P FR L EDQI LLK +A+E+ + N +F +
Sbjct: 224 LSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDD 283
Query: 186 QNFLCG--PLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDR 243
++ CG +Y + D + G +E +E L F L+KL L E E+VLL A+ + SPDR
Sbjct: 284 MSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDR 343
Query: 244 PGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQ 300
PGV I+ +Q+ ++ TLQ+YI+ + P LYAK++ LA+LRS+NE + Q
Sbjct: 344 PGVQDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQ 400
Score = 87.4 bits (215), Expect = 2e-17
Identities = 42/111 (37%), Positives = 65/111 (58%), Gaps = 5/111 (4%)
Query: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
RR++ + TCPF G C ++K RRHC ACRL++C+D GM K+ IL+ E + +R
Sbjct: 49 RRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMIL 108
Query: 67 QRRAQQT-----PVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHL 112
+R+ ++ +LS+EQ+ +I LL AH + + F QFRPP +
Sbjct: 109 KRKEEEALKDSLRPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRV 159
>gi|4507883 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo
sapiens]
Length = 427
Score = 130 bits (328), Expect = 1e-30
Identities = 69/177 (38%), Positives = 107/177 (60%), Gaps = 2/177 (1%)
Query: 126 LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQT 185
L ++ H AD+ ++ + +VI F K +P FR L EDQI LLK +A+E+ + N +F +
Sbjct: 224 LSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDD 283
Query: 186 QNFLCG--PLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDR 243
++ CG +Y + D + G +E +E L F L+KL L E E+VLL A+ + SPDR
Sbjct: 284 MSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDR 343
Query: 244 PGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQ 300
PGV I+ +Q+ ++ TLQ+YI+ + P LYAK++ LA+LRS+NE + Q
Sbjct: 344 PGVQDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQ 400
Score = 87.4 bits (215), Expect = 2e-17
Identities = 42/111 (37%), Positives = 65/111 (58%), Gaps = 5/111 (4%)
Query: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
RR++ + TCPF G C ++K RRHC ACRL++C+D GM K+ IL+ E + +R
Sbjct: 49 RRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMIL 108
Query: 67 QRRAQQT-----PVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHL 112
+R+ ++ +LS+EQ+ +I LL AH + + F QFRPP +
Sbjct: 109 KRKEEEALKDSLRPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRV 159
>gi|85362735 nuclear receptor subfamily 1, group H, member 2 [Homo
sapiens]
Length = 461
Score = 125 bits (314), Expect = 5e-29
Identities = 94/345 (27%), Positives = 156/345 (45%), Gaps = 58/345 (16%)
Query: 18 CPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTP--- 74
C G+C++ RR C CRL+KC +AGMR+ +LS E + ++ ++ Q++ Q+
Sbjct: 125 CRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQQESQSQSQS 184
Query: 75 ---------------------------------VQLSKEQEELIRTLLGAHTRHMGTMFE 101
VQL+ QE +I+ L+ A + F
Sbjct: 185 PVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFS 244
Query: 102 QFVQFRP------PAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRS 155
+ P P Q HF ++ V +++ F K +P F
Sbjct: 245 DQPKVTPWPLGADPQSRDARQQRF----------AHFTELAIISVQEIVDFAKQVPGFLQ 294
Query: 156 LPIEDQISLLKGAAVEICHIVLNTTFCLQTQ--NFLCGPLRYTIEDGARVGFQVEFLELL 213
L EDQI+LLK + +EI + + +T+ FL Y+ +D R G QVEF+ +
Sbjct: 295 LGREDQIALLKASTIEIMLLETARRYNHETECITFL-KDFTYSKDDFHRAGLQVEFINPI 353
Query: 214 FHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRR 273
F F +R+L L + EY LL A+ +FS DRP V + ++ LQ+ L SY + +R
Sbjct: 354 FEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTR--IKR 411
Query: 274 PRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMM-PLLQEI 317
P+D+ + ++L L LR+++ + Q+ ++ + PLL EI
Sbjct: 412 PQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEI 456
>gi|189491771 thyroid hormone receptor, beta [Homo sapiens]
Length = 461
Score = 118 bits (295), Expect = 8e-27
Identities = 93/319 (29%), Positives = 147/319 (46%), Gaps = 27/319 (8%)
Query: 7 RRTVSKSIGPT--CPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAK 64
RRT+ K++ P+ C + G C + K R C CR +KC+ GM D++L +R
Sbjct: 132 RRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKL 191
Query: 65 QAQRRAQQTPVQLSK----------EQEELIRTLLGAH--TRHMGTMFEQFVQFRPPAHL 112
+ R ++ +L K E+ ELI+T+ AH T G+ ++Q +F P
Sbjct: 192 IEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPED-- 249
Query: 113 FIHHQPLPTLAPV-----LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKG 167
I P+ AP L +HF I T + +V+ F K LP+F LP EDQI LLKG
Sbjct: 250 -IGQAPIVN-APEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKG 307
Query: 168 AAVEICHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQ 226
+EI + + +++ L G + T G V + +F +L L
Sbjct: 308 CCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGV-VSDAIFDLGMSLSSFNLD 366
Query: 227 EPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGL 286
+ E LL A+ L S DRPG+ + I++ Q+ L + YI R+ + KLL
Sbjct: 367 DTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYI--NYRKHHVTHFWPKLLMK 424
Query: 287 LAELRSINEAYGYQIQHIQ 305
+ +LR I + + H++
Sbjct: 425 VTDLRMIGACHASRFLHMK 443
>gi|189491769 thyroid hormone receptor, beta [Homo sapiens]
Length = 461
Score = 118 bits (295), Expect = 8e-27
Identities = 93/319 (29%), Positives = 147/319 (46%), Gaps = 27/319 (8%)
Query: 7 RRTVSKSIGPT--CPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAK 64
RRT+ K++ P+ C + G C + K R C CR +KC+ GM D++L +R
Sbjct: 132 RRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKL 191
Query: 65 QAQRRAQQTPVQLSK----------EQEELIRTLLGAH--TRHMGTMFEQFVQFRPPAHL 112
+ R ++ +L K E+ ELI+T+ AH T G+ ++Q +F P
Sbjct: 192 IEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPED-- 249
Query: 113 FIHHQPLPTLAPV-----LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKG 167
I P+ AP L +HF I T + +V+ F K LP+F LP EDQI LLKG
Sbjct: 250 -IGQAPIVN-APEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKG 307
Query: 168 AAVEICHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQ 226
+EI + + +++ L G + T G V + +F +L L
Sbjct: 308 CCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGV-VSDAIFDLGMSLSSFNLD 366
Query: 227 EPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGL 286
+ E LL A+ L S DRPG+ + I++ Q+ L + YI R+ + KLL
Sbjct: 367 DTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYI--NYRKHHVTHFWPKLLMK 424
Query: 287 LAELRSINEAYGYQIQHIQ 305
+ +LR I + + H++
Sbjct: 425 VTDLRMIGACHASRFLHMK 443
>gi|40806162 thyroid hormone receptor, beta [Homo sapiens]
Length = 461
Score = 118 bits (295), Expect = 8e-27
Identities = 93/319 (29%), Positives = 147/319 (46%), Gaps = 27/319 (8%)
Query: 7 RRTVSKSIGPT--CPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAK 64
RRT+ K++ P+ C + G C + K R C CR +KC+ GM D++L +R
Sbjct: 132 RRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKL 191
Query: 65 QAQRRAQQTPVQLSK----------EQEELIRTLLGAH--TRHMGTMFEQFVQFRPPAHL 112
+ R ++ +L K E+ ELI+T+ AH T G+ ++Q +F P
Sbjct: 192 IEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPED-- 249
Query: 113 FIHHQPLPTLAPV-----LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKG 167
I P+ AP L +HF I T + +V+ F K LP+F LP EDQI LLKG
Sbjct: 250 -IGQAPIVN-APEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKG 307
Query: 168 AAVEICHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQ 226
+EI + + +++ L G + T G V + +F +L L
Sbjct: 308 CCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGV-VSDAIFDLGMSLSSFNLD 366
Query: 227 EPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGL 286
+ E LL A+ L S DRPG+ + I++ Q+ L + YI R+ + KLL
Sbjct: 367 DTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYI--NYRKHHVTHFWPKLLMK 424
Query: 287 LAELRSINEAYGYQIQHIQ 305
+ +LR I + + H++
Sbjct: 425 VTDLRMIGACHASRFLHMK 443
>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 112 bits (280), Expect = 4e-25
Identities = 90/318 (28%), Positives = 154/318 (48%), Gaps = 24/318 (7%)
Query: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
RR++ K++ TC +C ++K R C CRLQKC + GM K+ + + ++ K+
Sbjct: 113 RRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRN---KKKKEV 169
Query: 67 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
+ L+ E ELI + AH E F ++ ++ +
Sbjct: 170 PKPECSESYTLTPEVGELIEKVRKAHQ-------ETFPALCQLGKYTTNNSSEQRVSLDI 222
Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQ-- 184
L F++++T +++ ++F K LP F +L I DQI+LLK A ++I + + T + +
Sbjct: 223 DLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQD 282
Query: 185 TQNFLCG-PLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDR 243
T F G L T A G +L+F F L L++ + E LL+A+ L DR
Sbjct: 283 TMTFSDGLTLNRTQMHNAGFG---PLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDR 339
Query: 244 PGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQI-- 301
+ Q D +D LQE + L+ Y++ +RRP ++ K+L + +LRSI+ ++
Sbjct: 340 QDLEQPDRVDMLQEPLLEALKVYVR--KRRPSRPHMFPKMLMKITDLRSISAKGAERVIT 397
Query: 302 --QHIQGLSAMMPLLQEI 317
I G +M PL+QE+
Sbjct: 398 LKMEIPG--SMPPLIQEM 413
>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
Length = 457
Score = 112 bits (280), Expect = 4e-25
Identities = 90/318 (28%), Positives = 154/318 (48%), Gaps = 24/318 (7%)
Query: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
RR++ K++ TC +C ++K R C CRLQKC + GM K+ + + ++ K+
Sbjct: 108 RRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRN---KKKKEV 164
Query: 67 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
+ L+ E ELI + AH E F ++ ++ +
Sbjct: 165 PKPECSESYTLTPEVGELIEKVRKAHQ-------ETFPALCQLGKYTTNNSSEQRVSLDI 217
Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQ-- 184
L F++++T +++ ++F K LP F +L I DQI+LLK A ++I + + T + +
Sbjct: 218 DLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQD 277
Query: 185 TQNFLCG-PLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDR 243
T F G L T A G +L+F F L L++ + E LL+A+ L DR
Sbjct: 278 TMTFSDGLTLNRTQMHNAGFG---PLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDR 334
Query: 244 PGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQI-- 301
+ Q D +D LQE + L+ Y++ +RRP ++ K+L + +LRSI+ ++
Sbjct: 335 QDLEQPDRVDMLQEPLLEALKVYVR--KRRPSRPHMFPKMLMKITDLRSISAKGAERVIT 392
Query: 302 --QHIQGLSAMMPLLQEI 317
I G +M PL+QE+
Sbjct: 393 LKMEIPG--SMPPLIQEM 408
>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 112 bits (280), Expect = 4e-25
Identities = 90/318 (28%), Positives = 154/318 (48%), Gaps = 24/318 (7%)
Query: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
RR++ K++ TC +C ++K R C CRLQKC + GM K+ + + ++ K+
Sbjct: 113 RRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRN---KKKKEV 169
Query: 67 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
+ L+ E ELI + AH E F ++ ++ +
Sbjct: 170 PKPECSESYTLTPEVGELIEKVRKAHQ-------ETFPALCQLGKYTTNNSSEQRVSLDI 222
Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQ-- 184
L F++++T +++ ++F K LP F +L I DQI+LLK A ++I + + T + +
Sbjct: 223 DLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQD 282
Query: 185 TQNFLCG-PLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDR 243
T F G L T A G +L+F F L L++ + E LL+A+ L DR
Sbjct: 283 TMTFSDGLTLNRTQMHNAGFG---PLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDR 339
Query: 244 PGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQI-- 301
+ Q D +D LQE + L+ Y++ +RRP ++ K+L + +LRSI+ ++
Sbjct: 340 QDLEQPDRVDMLQEPLLEALKVYVR--KRRPSRPHMFPKMLMKITDLRSISAKGAERVIT 397
Query: 302 --QHIQGLSAMMPLLQEI 317
I G +M PL+QE+
Sbjct: 398 LKMEIPG--SMPPLIQEM 413
>gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]
Length = 443
Score = 111 bits (277), Expect = 1e-24
Identities = 82/291 (28%), Positives = 143/291 (49%), Gaps = 18/291 (6%)
Query: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
RR++ K++ TC +C ++K R C CRLQKC + GM K+ + + ++ K+
Sbjct: 104 RRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRN---KKKKEV 160
Query: 67 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
+ +LS + EELI + AH E F + + L
Sbjct: 161 KEEGSPDSYELSPQLEELITKVSKAHQ-------ETFPSLCQLGKYTTNSSADHRVQLDL 213
Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQ-- 184
L F+++ T ++++++F K LP F L I DQI+LLK A ++I + + T + +
Sbjct: 214 GLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQD 273
Query: 185 TQNFLCG-PLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDR 243
T F G L T A G +L+F F G L L++ + E LL+A+ L DR
Sbjct: 274 TMTFSDGLTLNRTQMHNAGFG---PLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDR 330
Query: 244 PGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSIN 294
+ + +++D+LQE + L+ Y ++RRP +++ ++L + +LR I+
Sbjct: 331 MDLEEPEKVDKLQEPLLEALRLY--ARRRRPSQPYMFPRMLMKITDLRGIS 379
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.139 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,483,454
Number of Sequences: 37866
Number of extensions: 486777
Number of successful extensions: 2158
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 120
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1840
Number of HSP's gapped (non-prelim): 199
length of query: 319
length of database: 18,247,518
effective HSP length: 102
effective length of query: 217
effective length of database: 14,385,186
effective search space: 3121585362
effective search space used: 3121585362
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.