Search of human proteins with 117938748

Search of human proteins with 117938748

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|117938748 constitutive androstane receptor isoform 14 [Homo
sapiens]
         (306 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|117938748 constitutive androstane receptor isoform 14 [Homo s...   623   e-179
gi|117938744 constitutive androstane receptor isoform 13 [Homo s...   617   e-177
gi|117938738 constitutive androstane receptor isoform 12 [Homo s...   611   e-175
gi|117938746 constitutive androstane receptor isoform 7 [Homo sa...   606   e-174
gi|117938729 constitutive androstane receptor isoform 6 [Homo sa...   605   e-173
gi|117938750 constitutive androstane receptor isoform 10 [Homo s...   557   e-159
gi|117938736 constitutive androstane receptor isoform 9 [Homo sa...   551   e-157
gi|4826661 constitutive androstane receptor isoform 3 [Homo sapi...   545   e-155
gi|117938752 constitutive androstane receptor isoform 2 [Homo sa...   540   e-154
gi|117938756 constitutive androstane receptor isoform 1 [Homo sa...   533   e-152
gi|117938742 constitutive androstane receptor isoform 15 [Homo s...   528   e-150
gi|117938740 constitutive androstane receptor isoform 8 [Homo sa...   516   e-147
gi|117938732 constitutive androstane receptor isoform 11 [Homo s...   461   e-130
gi|117938754 constitutive androstane receptor isoform 4 [Homo sa...   452   e-127
gi|117938734 constitutive androstane receptor isoform 5 [Homo sa...   450   e-127
gi|14702164 nuclear receptor subfamily 1, group I, member 2 isof...   219   2e-57
gi|11863132 nuclear receptor subfamily 1, group I, member 2 isof...   208   5e-54
gi|34398348 nuclear receptor subfamily 1, group I, member 2 isof...   208   5e-54
gi|194294519 nuclear receptor subfamily 1, group H, member 3 iso...   127   9e-30
gi|194294517 nuclear receptor subfamily 1, group H, member 3 iso...   127   9e-30
gi|85362735 nuclear receptor subfamily 1, group H, member 2 [Hom...   113   2e-25
gi|189491771 thyroid hormone receptor, beta [Homo sapiens]            111   9e-25
gi|189491769 thyroid hormone receptor, beta [Homo sapiens]            111   9e-25
gi|40806162 thyroid hormone receptor, beta [Homo sapiens]             111   9e-25
gi|63054845 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo ...   108   6e-24
gi|4507883 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo s...   108   6e-24
gi|40806160 thyroid hormone receptor, alpha isoform 1 [Homo sapi...   103   1e-22
gi|20127452 thyroid hormone receptor, alpha isoform 2 [Homo sapi...   103   1e-22
gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]   101   7e-22
gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]     101   7e-22

>gi|117938748 constitutive androstane receptor isoform 14 [Homo
           sapiens]
          Length = 306

 Score =  623 bits (1607), Expect = e-179
 Identities = 306/306 (100%), Positives = 306/306 (100%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240
           FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240

Query: 241 PDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSK 300
           PDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSK
Sbjct: 241 PDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSK 300

Query: 301 GAQWLQ 306
           GAQWLQ
Sbjct: 301 GAQWLQ 306


>gi|117938744 constitutive androstane receptor isoform 13 [Homo
           sapiens]
          Length = 311

 Score =  617 bits (1591), Expect = e-177
 Identities = 306/311 (98%), Positives = 306/311 (98%), Gaps = 5/311 (1%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240
           FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240

Query: 241 P-----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKI 295
           P     DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKI
Sbjct: 241 PAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKI 300

Query: 296 GPGSKGAQWLQ 306
           GPGSKGAQWLQ
Sbjct: 301 GPGSKGAQWLQ 311


>gi|117938738 constitutive androstane receptor isoform 12 [Homo
           sapiens]
          Length = 315

 Score =  611 bits (1576), Expect = e-175
 Identities = 306/315 (97%), Positives = 306/315 (97%), Gaps = 9/315 (2%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGAR----VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAM 236
           FCLQTQNFLCGPLRYTIEDGAR    VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAM
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAM 240

Query: 237 ALFSP-----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKML 291
           ALFSP     DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKML
Sbjct: 241 ALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKML 300

Query: 292 GPKIGPGSKGAQWLQ 306
           GPKIGPGSKGAQWLQ
Sbjct: 301 GPKIGPGSKGAQWLQ 315


>gi|117938746 constitutive androstane receptor isoform 7 [Homo
           sapiens]
          Length = 339

 Score =  606 bits (1562), Expect = e-174
 Identities = 300/304 (98%), Positives = 300/304 (98%), Gaps = 4/304 (1%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGAR----VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD 242
           NFLCGPLRYTIEDGAR    VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD
Sbjct: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD 275

Query: 243 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGA 302
           RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGA
Sbjct: 276 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGA 335

Query: 303 QWLQ 306
           QWLQ
Sbjct: 336 QWLQ 339


>gi|117938729 constitutive androstane receptor isoform 6 [Homo
           sapiens]
          Length = 340

 Score =  605 bits (1561), Expect = e-173
 Identities = 300/305 (98%), Positives = 300/305 (98%), Gaps = 5/305 (1%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP----- 241
           NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP     
Sbjct: 216 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLT 275

Query: 242 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKG 301
           DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKG
Sbjct: 276 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKG 335

Query: 302 AQWLQ 306
           AQWLQ
Sbjct: 336 AQWLQ 340


>gi|117938750 constitutive androstane receptor isoform 10 [Homo
           sapiens]
          Length = 319

 Score =  557 bits (1435), Expect = e-159
 Identities = 277/277 (100%), Positives = 277/277 (100%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240
           FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240

Query: 241 PDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277
           PDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 241 PDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277


>gi|117938736 constitutive androstane receptor isoform 9 [Homo
           sapiens]
          Length = 324

 Score =  551 bits (1419), Expect = e-157
 Identities = 277/282 (98%), Positives = 277/282 (98%), Gaps = 5/282 (1%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240
           FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240

Query: 241 P-----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277
           P     DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 241 PAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 282


>gi|4826661 constitutive androstane receptor isoform 3 [Homo
           sapiens]
          Length = 348

 Score =  545 bits (1405), Expect = e-155
 Identities = 271/271 (100%), Positives = 271/271 (100%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGV 246
           NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGV
Sbjct: 216 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGV 275

Query: 247 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277
           TQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 276 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 306


>gi|117938752 constitutive androstane receptor isoform 2 [Homo
           sapiens]
          Length = 352

 Score =  540 bits (1390), Expect = e-154
 Identities = 271/275 (98%), Positives = 271/275 (98%), Gaps = 4/275 (1%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGAR----VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD 242
           NFLCGPLRYTIEDGAR    VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD
Sbjct: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD 275

Query: 243 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277
           RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 276 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 310


>gi|117938756 constitutive androstane receptor isoform 1 [Homo
           sapiens]
          Length = 357

 Score =  533 bits (1374), Expect = e-152
 Identities = 271/280 (96%), Positives = 271/280 (96%), Gaps = 9/280 (3%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGAR----VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP- 241
           NFLCGPLRYTIEDGAR    VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP 
Sbjct: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 275

Query: 242 ----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277
               DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 276 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 315


>gi|117938742 constitutive androstane receptor isoform 15 [Homo
           sapiens]
          Length = 267

 Score =  528 bits (1359), Expect = e-150
 Identities = 267/306 (87%), Positives = 267/306 (87%), Gaps = 39/306 (12%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240
           FCLQTQNFLCGPLRYTIEDGAR                                      
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGAR-------------------------------------- 202

Query: 241 PDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSK 300
            DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSK
Sbjct: 203 -DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSK 261

Query: 301 GAQWLQ 306
           GAQWLQ
Sbjct: 262 GAQWLQ 267


>gi|117938740 constitutive androstane receptor isoform 8 [Homo
           sapiens]
          Length = 296

 Score =  516 bits (1329), Expect = e-147
 Identities = 261/300 (87%), Positives = 261/300 (87%), Gaps = 39/300 (13%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGV 246
           NFLCGPLRYTIEDGAR                                       DRPGV
Sbjct: 216 NFLCGPLRYTIEDGAR---------------------------------------DRPGV 236

Query: 247 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ 306
           TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ
Sbjct: 237 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ 296


>gi|117938732 constitutive androstane receptor isoform 11 [Homo
           sapiens]
          Length = 280

 Score =  461 bits (1187), Expect = e-130
 Identities = 238/277 (85%), Positives = 238/277 (85%), Gaps = 39/277 (14%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240
           FCLQTQNFLCGPLRYTIEDGAR                                      
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGAR-------------------------------------- 202

Query: 241 PDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277
            DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 203 -DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238


>gi|117938754 constitutive androstane receptor isoform 4 [Homo
           sapiens]
          Length = 314

 Score =  452 bits (1163), Expect = e-127
 Identities = 233/271 (85%), Positives = 234/271 (86%), Gaps = 34/271 (12%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGV 246
           NFLCGPLRYTIEDGAR                                  A +  DRPGV
Sbjct: 216 NFLCGPLRYTIEDGAR----------------------------------APYLTDRPGV 241

Query: 247 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277
           TQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 242 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 272


>gi|117938734 constitutive androstane receptor isoform 5 [Homo
           sapiens]
          Length = 309

 Score =  450 bits (1157), Expect = e-127
 Identities = 232/271 (85%), Positives = 232/271 (85%), Gaps = 39/271 (14%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGV 246
           NFLCGPLRYTIEDGAR                                       DRPGV
Sbjct: 216 NFLCGPLRYTIEDGAR---------------------------------------DRPGV 236

Query: 247 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277
           TQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 237 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 267


>gi|14702164 nuclear receptor subfamily 1, group I, member 2 isoform
           3 [Homo sapiens]
          Length = 397

 Score =  219 bits (559), Expect = 2e-57
 Identities = 124/286 (43%), Positives = 174/286 (60%), Gaps = 16/286 (5%)

Query: 7   RRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQ 65
           RR + ++    CPF  G+CE+++  RR C ACRL+KCL++GM+K+MI+S EA+  RRA  
Sbjct: 66  RRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALI 125

Query: 66  AQRRAQQTPVQ------LSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPL 119
            ++++++T  Q      L++EQ  +IR L+ A  +   T F  F  FR    L      +
Sbjct: 126 KRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRVSLQLRGEDGSV 185

Query: 120 PTLAP--------VLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVE 171
               P        +  L+ H AD++T+M   +I F K +  FR LPIEDQISLLKGAA E
Sbjct: 186 WNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFE 245

Query: 172 ICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYV 231
           +C +  NT F  +T  + CG L Y +ED A  GFQ   LE +  FH  L+KLQL E EYV
Sbjct: 246 LCQLRFNTVFNAETGTWECGRLSYCLEDTAG-GFQQLLLEPMLKFHYMLKKLQLHEEEYV 304

Query: 232 LLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277
           L+ A++LFSPDRPGV Q   +DQLQE+ A+TL+SYI+  + +P  R
Sbjct: 305 LMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHR 350


>gi|11863132 nuclear receptor subfamily 1, group I, member 2 isoform
           2 [Homo sapiens]
          Length = 473

 Score =  208 bits (529), Expect = 5e-54
 Identities = 127/323 (39%), Positives = 177/323 (54%), Gaps = 53/323 (16%)

Query: 7   RRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQ 65
           RR + ++    CPF  G+CE+++  RR C ACRL+KCL++GM+K+MI+S EA+  RRA  
Sbjct: 105 RRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALI 164

Query: 66  AQRRAQQTPVQ------LSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQ-P 118
            ++++++T  Q      L++EQ  +IR L+ A  +   T F  F  FR P  L    + P
Sbjct: 165 KRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGCELP 224

Query: 119 LPTLAP--------------------------------------------VLPLVTHFAD 134
               AP                                            +  L+ H AD
Sbjct: 225 ESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMAD 284

Query: 135 INTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLR 194
           ++T+M   +I F K +  FR LPIEDQISLLKGAA E+C +  NT F  +T  + CG L 
Sbjct: 285 MSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLS 344

Query: 195 YTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQ 254
           Y +ED A  GFQ   LE +  FH  L+KLQL E EYVL+ A++LFSPDRPGV Q   +DQ
Sbjct: 345 YCLEDTAG-GFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQ 403

Query: 255 LQEEMALTLQSYIKGQQRRPRDR 277
           LQE+ A+TL+SYI+  + +P  R
Sbjct: 404 LQEQFAITLKSYIECNRPQPAHR 426


>gi|34398348 nuclear receptor subfamily 1, group I, member 2 isoform
           1 [Homo sapiens]
          Length = 434

 Score =  208 bits (529), Expect = 5e-54
 Identities = 127/323 (39%), Positives = 177/323 (54%), Gaps = 53/323 (16%)

Query: 7   RRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQ 65
           RR + ++    CPF  G+CE+++  RR C ACRL+KCL++GM+K+MI+S EA+  RRA  
Sbjct: 66  RRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALI 125

Query: 66  AQRRAQQTPVQ------LSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQ-P 118
            ++++++T  Q      L++EQ  +IR L+ A  +   T F  F  FR P  L    + P
Sbjct: 126 KRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGCELP 185

Query: 119 LPTLAP--------------------------------------------VLPLVTHFAD 134
               AP                                            +  L+ H AD
Sbjct: 186 ESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMAD 245

Query: 135 INTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLR 194
           ++T+M   +I F K +  FR LPIEDQISLLKGAA E+C +  NT F  +T  + CG L 
Sbjct: 246 MSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLS 305

Query: 195 YTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQ 254
           Y +ED A  GFQ   LE +  FH  L+KLQL E EYVL+ A++LFSPDRPGV Q   +DQ
Sbjct: 306 YCLEDTAG-GFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQ 364

Query: 255 LQEEMALTLQSYIKGQQRRPRDR 277
           LQE+ A+TL+SYI+  + +P  R
Sbjct: 365 LQEQFAITLKSYIECNRPQPAHR 387


>gi|194294519 nuclear receptor subfamily 1, group H, member 3
           isoform c [Homo sapiens]
          Length = 402

 Score =  127 bits (320), Expect = 9e-30
 Identities = 88/286 (30%), Positives = 137/286 (47%), Gaps = 22/286 (7%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR+V K     C   G C +    RR C  CRL+KC  AGMR++ +LS E + L++ K+ 
Sbjct: 78  RRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQ 137

Query: 67  QR----------RAQQTPV---QLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRP-PAHL 112
           +           RA   P    QLS EQ  +I  L+ A  +     F   ++  P P   
Sbjct: 138 EEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAP 197

Query: 113 FIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEI 172
             H +             HF ++    V +++ F K LP F  L  EDQI+LLK +A+E+
Sbjct: 198 DPHSREARQQR-----FAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEV 252

Query: 173 CHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYV 231
             +  +  +   +++        Y  ED A+ G QVEF+  +F F   + +LQL + E+ 
Sbjct: 253 MLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFA 312

Query: 232 LLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277
           LL A+++FS DRP V  + ++++LQ      L +Y+      P DR
Sbjct: 313 LLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYV--SIHHPHDR 356


>gi|194294517 nuclear receptor subfamily 1, group H, member 3
           isoform a [Homo sapiens]
          Length = 447

 Score =  127 bits (320), Expect = 9e-30
 Identities = 88/286 (30%), Positives = 137/286 (47%), Gaps = 22/286 (7%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR+V K     C   G C +    RR C  CRL+KC  AGMR++ +LS E + L++ K+ 
Sbjct: 123 RRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQ 182

Query: 67  QR----------RAQQTPV---QLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRP-PAHL 112
           +           RA   P    QLS EQ  +I  L+ A  +     F   ++  P P   
Sbjct: 183 EEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAP 242

Query: 113 FIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEI 172
             H +             HF ++    V +++ F K LP F  L  EDQI+LLK +A+E+
Sbjct: 243 DPHSREARQQR-----FAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEV 297

Query: 173 CHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYV 231
             +  +  +   +++        Y  ED A+ G QVEF+  +F F   + +LQL + E+ 
Sbjct: 298 MLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFA 357

Query: 232 LLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277
           LL A+++FS DRP V  + ++++LQ      L +Y+      P DR
Sbjct: 358 LLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYV--SIHHPHDR 401


>gi|85362735 nuclear receptor subfamily 1, group H, member 2 [Homo
           sapiens]
          Length = 461

 Score =  113 bits (282), Expect = 2e-25
 Identities = 84/304 (27%), Positives = 135/304 (44%), Gaps = 57/304 (18%)

Query: 18  CPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTP--- 74
           C   G+C++    RR C  CRL+KC +AGMR+  +LS E +  ++ ++ Q++  Q+    
Sbjct: 125 CRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQQESQSQSQS 184

Query: 75  ---------------------------------VQLSKEQEELIRTLLGAHTRHMGTMFE 101
                                            VQL+  QE +I+ L+ A  +     F 
Sbjct: 185 PVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFS 244

Query: 102 QFVQFRP------PAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRS 155
              +  P      P       Q             HF ++    V +++ F K +P F  
Sbjct: 245 DQPKVTPWPLGADPQSRDARQQRF----------AHFTELAIISVQEIVDFAKQVPGFLQ 294

Query: 156 LPIEDQISLLKGAAVEICHIVLNTTFCLQTQ--NFLCGPLRYTIEDGARVGFQVEFLELL 213
           L  EDQI+LLK + +EI  +     +  +T+   FL     Y+ +D  R G QVEF+  +
Sbjct: 295 LGREDQIALLKASTIEIMLLETARRYNHETECITFL-KDFTYSKDDFHRAGLQVEFINPI 353

Query: 214 FHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRR 273
           F F   +R+L L + EY LL A+ +FS DRP V +   ++ LQ+     L SY +   +R
Sbjct: 354 FEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTR--IKR 411

Query: 274 PRDR 277
           P+D+
Sbjct: 412 PQDQ 415


>gi|189491771 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score =  111 bits (277), Expect = 9e-25
 Identities = 85/281 (30%), Positives = 131/281 (46%), Gaps = 25/281 (8%)

Query: 7   RRTVSKSIGPT--CPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAK 64
           RRT+ K++ P+  C + G C + K  R  C  CR +KC+  GM  D++L       +R  
Sbjct: 132 RRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKL 191

Query: 65  QAQRRAQQTPVQLSK----------EQEELIRTLLGAH--TRHMGTMFEQFVQFRPPAHL 112
             + R ++   +L K          E+ ELI+T+  AH  T   G+ ++Q  +F P    
Sbjct: 192 IEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPED-- 249

Query: 113 FIHHQPLPTLAPV-----LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKG 167
            I   P+   AP      L   +HF  I T  + +V+ F K LP+F  LP EDQI LLKG
Sbjct: 250 -IGQAPIVN-APEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKG 307

Query: 168 AAVEICHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQ 226
             +EI  +     +  +++   L G +  T       G  V   + +F    +L    L 
Sbjct: 308 CCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGV-VSDAIFDLGMSLSSFNLD 366

Query: 227 EPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 267
           + E  LL A+ L S DRPG+   + I++ Q+   L  + YI
Sbjct: 367 DTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYI 407


>gi|189491769 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score =  111 bits (277), Expect = 9e-25
 Identities = 85/281 (30%), Positives = 131/281 (46%), Gaps = 25/281 (8%)

Query: 7   RRTVSKSIGPT--CPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAK 64
           RRT+ K++ P+  C + G C + K  R  C  CR +KC+  GM  D++L       +R  
Sbjct: 132 RRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKL 191

Query: 65  QAQRRAQQTPVQLSK----------EQEELIRTLLGAH--TRHMGTMFEQFVQFRPPAHL 112
             + R ++   +L K          E+ ELI+T+  AH  T   G+ ++Q  +F P    
Sbjct: 192 IEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPED-- 249

Query: 113 FIHHQPLPTLAPV-----LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKG 167
            I   P+   AP      L   +HF  I T  + +V+ F K LP+F  LP EDQI LLKG
Sbjct: 250 -IGQAPIVN-APEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKG 307

Query: 168 AAVEICHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQ 226
             +EI  +     +  +++   L G +  T       G  V   + +F    +L    L 
Sbjct: 308 CCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGV-VSDAIFDLGMSLSSFNLD 366

Query: 227 EPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 267
           + E  LL A+ L S DRPG+   + I++ Q+   L  + YI
Sbjct: 367 DTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYI 407


>gi|40806162 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score =  111 bits (277), Expect = 9e-25
 Identities = 85/281 (30%), Positives = 131/281 (46%), Gaps = 25/281 (8%)

Query: 7   RRTVSKSIGPT--CPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAK 64
           RRT+ K++ P+  C + G C + K  R  C  CR +KC+  GM  D++L       +R  
Sbjct: 132 RRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKL 191

Query: 65  QAQRRAQQTPVQLSK----------EQEELIRTLLGAH--TRHMGTMFEQFVQFRPPAHL 112
             + R ++   +L K          E+ ELI+T+  AH  T   G+ ++Q  +F P    
Sbjct: 192 IEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPED-- 249

Query: 113 FIHHQPLPTLAPV-----LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKG 167
            I   P+   AP      L   +HF  I T  + +V+ F K LP+F  LP EDQI LLKG
Sbjct: 250 -IGQAPIVN-APEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKG 307

Query: 168 AAVEICHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQ 226
             +EI  +     +  +++   L G +  T       G  V   + +F    +L    L 
Sbjct: 308 CCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGV-VSDAIFDLGMSLSSFNLD 366

Query: 227 EPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 267
           + E  LL A+ L S DRPG+   + I++ Q+   L  + YI
Sbjct: 367 DTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYI 407


>gi|63054845 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo
           sapiens]
          Length = 427

 Score =  108 bits (270), Expect = 6e-24
 Identities = 57/151 (37%), Positives = 90/151 (59%), Gaps = 2/151 (1%)

Query: 126 LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQT 185
           L ++ H AD+ ++ + +VI F K +P FR L  EDQI LLK +A+E+  +  N +F +  
Sbjct: 224 LSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDD 283

Query: 186 QNFLCG--PLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDR 243
            ++ CG    +Y + D  + G  +E +E L  F   L+KL L E E+VLL A+ + SPDR
Sbjct: 284 MSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDR 343

Query: 244 PGVTQRDEIDQLQEEMALTLQSYIKGQQRRP 274
           PGV     I+ +Q+ ++ TLQ+YI+ +   P
Sbjct: 344 PGVQDAALIEAIQDRLSNTLQTYIRCRHPPP 374



 Score = 87.4 bits (215), Expect = 1e-17
 Identities = 42/111 (37%), Positives = 65/111 (58%), Gaps = 5/111 (4%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR++ +    TCPF G C ++K  RRHC ACRL++C+D GM K+ IL+ E +  +R    
Sbjct: 49  RRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMIL 108

Query: 67  QRRAQQT-----PVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHL 112
           +R+ ++        +LS+EQ+ +I  LL AH +     +  F QFRPP  +
Sbjct: 109 KRKEEEALKDSLRPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRV 159


>gi|4507883 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo
           sapiens]
          Length = 427

 Score =  108 bits (270), Expect = 6e-24
 Identities = 57/151 (37%), Positives = 90/151 (59%), Gaps = 2/151 (1%)

Query: 126 LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQT 185
           L ++ H AD+ ++ + +VI F K +P FR L  EDQI LLK +A+E+  +  N +F +  
Sbjct: 224 LSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDD 283

Query: 186 QNFLCG--PLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDR 243
            ++ CG    +Y + D  + G  +E +E L  F   L+KL L E E+VLL A+ + SPDR
Sbjct: 284 MSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDR 343

Query: 244 PGVTQRDEIDQLQEEMALTLQSYIKGQQRRP 274
           PGV     I+ +Q+ ++ TLQ+YI+ +   P
Sbjct: 344 PGVQDAALIEAIQDRLSNTLQTYIRCRHPPP 374



 Score = 87.4 bits (215), Expect = 1e-17
 Identities = 42/111 (37%), Positives = 65/111 (58%), Gaps = 5/111 (4%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR++ +    TCPF G C ++K  RRHC ACRL++C+D GM K+ IL+ E +  +R    
Sbjct: 49  RRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMIL 108

Query: 67  QRRAQQT-----PVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHL 112
           +R+ ++        +LS+EQ+ +I  LL AH +     +  F QFRPP  +
Sbjct: 109 KRKEEEALKDSLRPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRV 159


>gi|40806160 thyroid hormone receptor, alpha isoform 1 [Homo
           sapiens]
          Length = 410

 Score =  103 bits (258), Expect = 1e-22
 Identities = 82/280 (29%), Positives = 126/280 (45%), Gaps = 23/280 (8%)

Query: 7   RRTVSKSIGPT--CPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILS---------- 54
           RRT+ K++ PT  C +   C + K  R  C  CR +KC+  GM  D++L           
Sbjct: 78  RRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRKL 137

Query: 55  AEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAH--TRHMGTMFEQFVQFRPPAHL 112
            E    RR K+   R+ Q   + + E+ +LI     AH  T   G+ ++Q  +F P    
Sbjct: 138 IEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNAQGSHWKQRRKFLPDD-- 195

Query: 113 FIHHQPLPTLAPV----LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGA 168
            I   P+ ++       L   + F  I T  + +V+ F K LP+F  LP EDQI LLKG 
Sbjct: 196 -IGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIILLKGC 254

Query: 169 AVEICHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQE 227
            +EI  +     +  ++    L G +    E     G  V   + +F    +L    L +
Sbjct: 255 CMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGV-VSDAIFELGKSLSAFNLDD 313

Query: 228 PEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 267
            E  LL A+ L S DR G+   D+I++ QE   L  + Y+
Sbjct: 314 TEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYV 353


>gi|20127452 thyroid hormone receptor, alpha isoform 2 [Homo
           sapiens]
          Length = 490

 Score =  103 bits (258), Expect = 1e-22
 Identities = 82/280 (29%), Positives = 126/280 (45%), Gaps = 23/280 (8%)

Query: 7   RRTVSKSIGPT--CPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILS---------- 54
           RRT+ K++ PT  C +   C + K  R  C  CR +KC+  GM  D++L           
Sbjct: 78  RRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRKL 137

Query: 55  AEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAH--TRHMGTMFEQFVQFRPPAHL 112
            E    RR K+   R+ Q   + + E+ +LI     AH  T   G+ ++Q  +F P    
Sbjct: 138 IEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNAQGSHWKQRRKFLPDD-- 195

Query: 113 FIHHQPLPTLAPV----LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGA 168
            I   P+ ++       L   + F  I T  + +V+ F K LP+F  LP EDQI LLKG 
Sbjct: 196 -IGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIILLKGC 254

Query: 169 AVEICHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQE 227
            +EI  +     +  ++    L G +    E     G  V   + +F    +L    L +
Sbjct: 255 CMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGV-VSDAIFELGKSLSAFNLDD 313

Query: 228 PEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 267
            E  LL A+ L S DR G+   D+I++ QE   L  + Y+
Sbjct: 314 TEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYV 353


>gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]
          Length = 443

 Score =  101 bits (252), Expect = 7e-22
 Identities = 78/271 (28%), Positives = 131/271 (48%), Gaps = 18/271 (6%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR++ K++  TC    +C ++K  R  C  CRLQKC + GM K+ + +      ++ K+ 
Sbjct: 104 RRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRN---KKKKEV 160

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           +        +LS + EELI  +  AH        E F           +      +   L
Sbjct: 161 KEEGSPDSYELSPQLEELITKVSKAHQ-------ETFPSLCQLGKYTTNSSADHRVQLDL 213

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQ-- 184
            L   F+++ T  ++++++F K LP F  L I DQI+LLK A ++I  + + T +  +  
Sbjct: 214 GLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQD 273

Query: 185 TQNFLCG-PLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDR 243
           T  F  G  L  T    A  G      +L+F F G L  L++ + E  LL+A+ L   DR
Sbjct: 274 TMTFSDGLTLNRTQMHNAGFG---PLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDR 330

Query: 244 PGVTQRDEIDQLQEEMALTLQSYIKGQQRRP 274
             + + +++D+LQE +   L+ Y   ++RRP
Sbjct: 331 MDLEEPEKVDKLQEPLLEALRLY--ARRRRP 359


>gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]
          Length = 454

 Score =  101 bits (252), Expect = 7e-22
 Identities = 78/271 (28%), Positives = 131/271 (48%), Gaps = 18/271 (6%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR++ K++  TC    +C ++K  R  C  CRLQKC + GM K+ + +      ++ K+ 
Sbjct: 115 RRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRN---KKKKEV 171

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           +        +LS + EELI  +  AH        E F           +      +   L
Sbjct: 172 KEEGSPDSYELSPQLEELITKVSKAHQ-------ETFPSLCQLGKYTTNSSADHRVQLDL 224

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQ-- 184
            L   F+++ T  ++++++F K LP F  L I DQI+LLK A ++I  + + T +  +  
Sbjct: 225 GLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQD 284

Query: 185 TQNFLCG-PLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDR 243
           T  F  G  L  T    A  G      +L+F F G L  L++ + E  LL+A+ L   DR
Sbjct: 285 TMTFSDGLTLNRTQMHNAGFG---PLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDR 341

Query: 244 PGVTQRDEIDQLQEEMALTLQSYIKGQQRRP 274
             + + +++D+LQE +   L+ Y   ++RRP
Sbjct: 342 MDLEEPEKVDKLQEPLLEALRLY--ARRRRP 370


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.138    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,115,997
Number of Sequences: 37866
Number of extensions: 542274
Number of successful extensions: 2351
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 121
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 2056
Number of HSP's gapped (non-prelim): 198
length of query: 306
length of database: 18,247,518
effective HSP length: 102
effective length of query: 204
effective length of database: 14,385,186
effective search space: 2934577944
effective search space used: 2934577944
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.