Search of human proteins with 117938736

Search of human proteins with 117938736

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|117938736 constitutive androstane receptor isoform 9 [Homo
sapiens]
         (324 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|117938736 constitutive androstane receptor isoform 9 [Homo sa...   648   0.0  
gi|117938750 constitutive androstane receptor isoform 10 [Homo s...   632   0.0  
gi|117938756 constitutive androstane receptor isoform 1 [Homo sa...   631   0.0  
gi|4826661 constitutive androstane receptor isoform 3 [Homo sapi...   620   e-178
gi|117938752 constitutive androstane receptor isoform 2 [Homo sa...   614   e-176
gi|117938744 constitutive androstane receptor isoform 13 [Homo s...   567   e-162
gi|117938738 constitutive androstane receptor isoform 12 [Homo s...   561   e-160
gi|117938729 constitutive androstane receptor isoform 6 [Homo sa...   556   e-158
gi|117938748 constitutive androstane receptor isoform 14 [Homo s...   551   e-157
gi|117938754 constitutive androstane receptor isoform 4 [Homo sa...   541   e-154
gi|117938732 constitutive androstane receptor isoform 11 [Homo s...   540   e-154
gi|117938746 constitutive androstane receptor isoform 7 [Homo sa...   533   e-152
gi|117938734 constitutive androstane receptor isoform 5 [Homo sa...   529   e-150
gi|117938742 constitutive androstane receptor isoform 15 [Homo s...   459   e-129
gi|117938740 constitutive androstane receptor isoform 8 [Homo sa...   448   e-126
gi|14702164 nuclear receptor subfamily 1, group I, member 2 isof...   241   5e-64
gi|11863132 nuclear receptor subfamily 1, group I, member 2 isof...   230   1e-60
gi|34398348 nuclear receptor subfamily 1, group I, member 2 isof...   230   1e-60
gi|194294519 nuclear receptor subfamily 1, group H, member 3 iso...   135   4e-32
gi|194294517 nuclear receptor subfamily 1, group H, member 3 iso...   135   4e-32
gi|63054845 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo ...   124   9e-29
gi|4507883 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo s...   124   9e-29
gi|85362735 nuclear receptor subfamily 1, group H, member 2 [Hom...   119   3e-27
gi|189491771 thyroid hormone receptor, beta [Homo sapiens]            112   3e-25
gi|189491769 thyroid hormone receptor, beta [Homo sapiens]            112   3e-25
gi|40806162 thyroid hormone receptor, beta [Homo sapiens]             112   3e-25
gi|40806160 thyroid hormone receptor, alpha isoform 1 [Homo sapi...   107   2e-23
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]   106   3e-23
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]    106   3e-23
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]     106   3e-23

>gi|117938736 constitutive androstane receptor isoform 9 [Homo
           sapiens]
          Length = 324

 Score =  648 bits (1672), Expect = 0.0
 Identities = 324/324 (100%), Positives = 324/324 (100%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240
           FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240

Query: 241 PAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINE 300
           PAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINE
Sbjct: 241 PAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINE 300

Query: 301 AYGYQIQHIQGLSAMMPLLQEICS 324
           AYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 301 AYGYQIQHIQGLSAMMPLLQEICS 324


>gi|117938750 constitutive androstane receptor isoform 10 [Homo
           sapiens]
          Length = 319

 Score =  632 bits (1629), Expect = 0.0
 Identities = 319/324 (98%), Positives = 319/324 (98%), Gaps = 5/324 (1%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240
           FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240

Query: 241 PAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINE 300
           P     DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINE
Sbjct: 241 P-----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINE 295

Query: 301 AYGYQIQHIQGLSAMMPLLQEICS 324
           AYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 296 AYGYQIQHIQGLSAMMPLLQEICS 319


>gi|117938756 constitutive androstane receptor isoform 1 [Homo
           sapiens]
          Length = 357

 Score =  631 bits (1627), Expect = 0.0
 Identities = 318/322 (98%), Positives = 318/322 (98%), Gaps = 4/322 (1%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGAR----VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 242
           NFLCGPLRYTIEDGAR    VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA
Sbjct: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 275

Query: 243 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAY 302
           PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAY
Sbjct: 276 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAY 335

Query: 303 GYQIQHIQGLSAMMPLLQEICS 324
           GYQIQHIQGLSAMMPLLQEICS
Sbjct: 336 GYQIQHIQGLSAMMPLLQEICS 357


>gi|4826661 constitutive androstane receptor isoform 3 [Homo
           sapiens]
          Length = 348

 Score =  620 bits (1599), Expect = e-178
 Identities = 313/318 (98%), Positives = 313/318 (98%), Gaps = 5/318 (1%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLT 246
           NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP     
Sbjct: 216 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP----- 270

Query: 247 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQI 306
           DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQI
Sbjct: 271 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQI 330

Query: 307 QHIQGLSAMMPLLQEICS 324
           QHIQGLSAMMPLLQEICS
Sbjct: 331 QHIQGLSAMMPLLQEICS 348


>gi|117938752 constitutive androstane receptor isoform 2 [Homo
           sapiens]
          Length = 352

 Score =  614 bits (1584), Expect = e-176
 Identities = 313/322 (97%), Positives = 313/322 (97%), Gaps = 9/322 (2%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGAR----VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 242
           NFLCGPLRYTIEDGAR    VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP 
Sbjct: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP- 274

Query: 243 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAY 302
               DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAY
Sbjct: 275 ----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAY 330

Query: 303 GYQIQHIQGLSAMMPLLQEICS 324
           GYQIQHIQGLSAMMPLLQEICS
Sbjct: 331 GYQIQHIQGLSAMMPLLQEICS 352


>gi|117938744 constitutive androstane receptor isoform 13 [Homo
           sapiens]
          Length = 311

 Score =  567 bits (1462), Expect = e-162
 Identities = 282/282 (100%), Positives = 282/282 (100%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240
           FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240

Query: 241 PAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 282
           PAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 241 PAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 282


>gi|117938738 constitutive androstane receptor isoform 12 [Homo
           sapiens]
          Length = 315

 Score =  561 bits (1447), Expect = e-160
 Identities = 282/286 (98%), Positives = 282/286 (98%), Gaps = 4/286 (1%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGAR----VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAM 236
           FCLQTQNFLCGPLRYTIEDGAR    VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAM
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAM 240

Query: 237 ALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 282
           ALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 241 ALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 286


>gi|117938729 constitutive androstane receptor isoform 6 [Homo
           sapiens]
          Length = 340

 Score =  556 bits (1432), Expect = e-158
 Identities = 276/276 (100%), Positives = 276/276 (100%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLT 246
           NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLT
Sbjct: 216 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLT 275

Query: 247 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 282
           DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 276 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 311


>gi|117938748 constitutive androstane receptor isoform 14 [Homo
           sapiens]
          Length = 306

 Score =  551 bits (1419), Expect = e-157
 Identities = 277/282 (98%), Positives = 277/282 (98%), Gaps = 5/282 (1%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240
           FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240

Query: 241 PAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 282
           P     DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 241 P-----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277


>gi|117938754 constitutive androstane receptor isoform 4 [Homo
           sapiens]
          Length = 314

 Score =  541 bits (1394), Expect = e-154
 Identities = 279/318 (87%), Positives = 279/318 (87%), Gaps = 39/318 (12%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLT 246
           NFLCGPLRYTIEDGAR                                       APYLT
Sbjct: 216 NFLCGPLRYTIEDGAR---------------------------------------APYLT 236

Query: 247 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQI 306
           DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQI
Sbjct: 237 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQI 296

Query: 307 QHIQGLSAMMPLLQEICS 324
           QHIQGLSAMMPLLQEICS
Sbjct: 297 QHIQGLSAMMPLLQEICS 314


>gi|117938732 constitutive androstane receptor isoform 11 [Homo
           sapiens]
          Length = 280

 Score =  540 bits (1392), Expect = e-154
 Identities = 280/324 (86%), Positives = 280/324 (86%), Gaps = 44/324 (13%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240
           FCLQTQNFLCGPLRYTIEDGAR                                      
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGAR-------------------------------------- 202

Query: 241 PAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINE 300
                 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINE
Sbjct: 203 ------DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINE 256

Query: 301 AYGYQIQHIQGLSAMMPLLQEICS 324
           AYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 257 AYGYQIQHIQGLSAMMPLLQEICS 280


>gi|117938746 constitutive androstane receptor isoform 7 [Homo
           sapiens]
          Length = 339

 Score =  533 bits (1374), Expect = e-152
 Identities = 271/280 (96%), Positives = 271/280 (96%), Gaps = 9/280 (3%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGAR----VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 242
           NFLCGPLRYTIEDGAR    VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP 
Sbjct: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP- 274

Query: 243 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 282
               DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 275 ----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 310


>gi|117938734 constitutive androstane receptor isoform 5 [Homo
           sapiens]
          Length = 309

 Score =  529 bits (1362), Expect = e-150
 Identities = 274/318 (86%), Positives = 274/318 (86%), Gaps = 44/318 (13%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLT 246
           NFLCGPLRYTIEDGAR                                            
Sbjct: 216 NFLCGPLRYTIEDGAR-------------------------------------------- 231

Query: 247 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQI 306
           DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQI
Sbjct: 232 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQI 291

Query: 307 QHIQGLSAMMPLLQEICS 324
           QHIQGLSAMMPLLQEICS
Sbjct: 292 QHIQGLSAMMPLLQEICS 309


>gi|117938742 constitutive androstane receptor isoform 15 [Homo
           sapiens]
          Length = 267

 Score =  459 bits (1182), Expect = e-129
 Identities = 238/282 (84%), Positives = 238/282 (84%), Gaps = 44/282 (15%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240
           FCLQTQNFLCGPLRYTIEDGAR                                      
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGAR-------------------------------------- 202

Query: 241 PAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 282
                 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 203 ------DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238


>gi|117938740 constitutive androstane receptor isoform 8 [Homo
           sapiens]
          Length = 296

 Score =  448 bits (1152), Expect = e-126
 Identities = 232/276 (84%), Positives = 232/276 (84%), Gaps = 44/276 (15%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLT 246
           NFLCGPLRYTIEDGAR                                            
Sbjct: 216 NFLCGPLRYTIEDGAR-------------------------------------------- 231

Query: 247 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 282
           DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 232 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 267


>gi|14702164 nuclear receptor subfamily 1, group I, member 2 isoform
           3 [Homo sapiens]
          Length = 397

 Score =  241 bits (616), Expect = 5e-64
 Identities = 140/332 (42%), Positives = 200/332 (60%), Gaps = 22/332 (6%)

Query: 7   RRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQ 65
           RR + ++    CPF  G+CE+++  RR C ACRL+KCL++GM+K+MI+S EA+  RRA  
Sbjct: 66  RRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALI 125

Query: 66  AQRRAQQTPVQ------LSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPL 119
            ++++++T  Q      L++EQ  +IR L+ A  +   T F  F  FR    L      +
Sbjct: 126 KRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRVSLQLRGEDGSV 185

Query: 120 PTLAP--------VLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVE 171
               P        +  L+ H AD++T+M   +I F K +  FR LPIEDQISLLKGAA E
Sbjct: 186 WNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFE 245

Query: 172 ICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYV 231
           +C +  NT F  +T  + CG L Y +ED A  GFQ   LE +  FH  L+KLQL E EYV
Sbjct: 246 LCQLRFNTVFNAETGTWECGRLSYCLEDTAG-GFQQLLLEPMLKFHYMLKKLQLHEEEYV 304

Query: 232 LLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGL 291
           L+ A++LFSP     DRPGV Q   +DQLQE+ A+TL+SYI+  + +P  RFL+ K++ +
Sbjct: 305 LMQAISLFSP-----DRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAM 359

Query: 292 LAELRSINEAYGYQIQHIQGLSAM-MPLLQEI 322
           L ELRSIN  +  ++  IQ +     PL+QE+
Sbjct: 360 LTELRSINAQHTQRLLRIQDIHPFATPLMQEL 391


>gi|11863132 nuclear receptor subfamily 1, group I, member 2 isoform
           2 [Homo sapiens]
          Length = 473

 Score =  230 bits (586), Expect = 1e-60
 Identities = 143/369 (38%), Positives = 203/369 (55%), Gaps = 59/369 (15%)

Query: 7   RRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQ 65
           RR + ++    CPF  G+CE+++  RR C ACRL+KCL++GM+K+MI+S EA+  RRA  
Sbjct: 105 RRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALI 164

Query: 66  AQRRAQQTPVQ------LSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQ-P 118
            ++++++T  Q      L++EQ  +IR L+ A  +   T F  F  FR P  L    + P
Sbjct: 165 KRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGCELP 224

Query: 119 LPTLAP--------------------------------------------VLPLVTHFAD 134
               AP                                            +  L+ H AD
Sbjct: 225 ESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMAD 284

Query: 135 INTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLR 194
           ++T+M   +I F K +  FR LPIEDQISLLKGAA E+C +  NT F  +T  + CG L 
Sbjct: 285 MSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLS 344

Query: 195 YTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQR 254
           Y +ED A  GFQ   LE +  FH  L+KLQL E EYVL+ A++LFSP     DRPGV Q 
Sbjct: 345 YCLEDTAG-GFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSP-----DRPGVLQH 398

Query: 255 DEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSA 314
             +DQLQE+ A+TL+SYI+  + +P  RFL+ K++ +L ELRSIN  +  ++  IQ +  
Sbjct: 399 RVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHP 458

Query: 315 M-MPLLQEI 322
              PL+QE+
Sbjct: 459 FATPLMQEL 467


>gi|34398348 nuclear receptor subfamily 1, group I, member 2 isoform
           1 [Homo sapiens]
          Length = 434

 Score =  230 bits (586), Expect = 1e-60
 Identities = 143/369 (38%), Positives = 203/369 (55%), Gaps = 59/369 (15%)

Query: 7   RRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQ 65
           RR + ++    CPF  G+CE+++  RR C ACRL+KCL++GM+K+MI+S EA+  RRA  
Sbjct: 66  RRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALI 125

Query: 66  AQRRAQQTPVQ------LSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQ-P 118
            ++++++T  Q      L++EQ  +IR L+ A  +   T F  F  FR P  L    + P
Sbjct: 126 KRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGCELP 185

Query: 119 LPTLAP--------------------------------------------VLPLVTHFAD 134
               AP                                            +  L+ H AD
Sbjct: 186 ESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMAD 245

Query: 135 INTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLR 194
           ++T+M   +I F K +  FR LPIEDQISLLKGAA E+C +  NT F  +T  + CG L 
Sbjct: 246 MSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLS 305

Query: 195 YTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQR 254
           Y +ED A  GFQ   LE +  FH  L+KLQL E EYVL+ A++LFSP     DRPGV Q 
Sbjct: 306 YCLEDTAG-GFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSP-----DRPGVLQH 359

Query: 255 DEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSA 314
             +DQLQE+ A+TL+SYI+  + +P  RFL+ K++ +L ELRSIN  +  ++  IQ +  
Sbjct: 360 RVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHP 419

Query: 315 M-MPLLQEI 322
              PL+QE+
Sbjct: 420 FATPLMQEL 428


>gi|194294519 nuclear receptor subfamily 1, group H, member 3
           isoform c [Homo sapiens]
          Length = 402

 Score =  135 bits (341), Expect = 4e-32
 Identities = 98/332 (29%), Positives = 159/332 (47%), Gaps = 28/332 (8%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR+V K     C   G C +    RR C  CRL+KC  AGMR++ +LS E + L++ K+ 
Sbjct: 78  RRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQ 137

Query: 67  QR----------RAQQTP---VQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRP-PAHL 112
           +           RA   P    QLS EQ  +I  L+ A  +     F   ++  P P   
Sbjct: 138 EEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAP 197

Query: 113 FIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEI 172
             H +             HF ++    V +++ F K LP F  L  EDQI+LLK +A+E+
Sbjct: 198 DPHSREARQ-----QRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEV 252

Query: 173 CHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYV 231
             +  +  +   +++        Y  ED A+ G QVEF+  +F F   + +LQL + E+ 
Sbjct: 253 MLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFA 312

Query: 232 LLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGL 291
           LL A+++FS      DRP V  + ++++LQ      L +Y+      P DR ++ ++L  
Sbjct: 313 LLIAISIFS-----ADRPNVQDQLQVERLQHTYVEALHAYV--SIHHPHDRLMFPRMLMK 365

Query: 292 LAELRSINEAYGYQIQHIQGLSAMM-PLLQEI 322
           L  LR+++  +  Q+  ++     + PLL EI
Sbjct: 366 LVSLRTLSSVHSEQVFALRLQDKKLPPLLSEI 397


>gi|194294517 nuclear receptor subfamily 1, group H, member 3
           isoform a [Homo sapiens]
          Length = 447

 Score =  135 bits (341), Expect = 4e-32
 Identities = 98/332 (29%), Positives = 159/332 (47%), Gaps = 28/332 (8%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR+V K     C   G C +    RR C  CRL+KC  AGMR++ +LS E + L++ K+ 
Sbjct: 123 RRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQ 182

Query: 67  QR----------RAQQTP---VQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRP-PAHL 112
           +           RA   P    QLS EQ  +I  L+ A  +     F   ++  P P   
Sbjct: 183 EEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAP 242

Query: 113 FIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEI 172
             H +             HF ++    V +++ F K LP F  L  EDQI+LLK +A+E+
Sbjct: 243 DPHSREARQ-----QRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEV 297

Query: 173 CHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYV 231
             +  +  +   +++        Y  ED A+ G QVEF+  +F F   + +LQL + E+ 
Sbjct: 298 MLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFA 357

Query: 232 LLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGL 291
           LL A+++FS      DRP V  + ++++LQ      L +Y+      P DR ++ ++L  
Sbjct: 358 LLIAISIFS-----ADRPNVQDQLQVERLQHTYVEALHAYV--SIHHPHDRLMFPRMLMK 410

Query: 292 LAELRSINEAYGYQIQHIQGLSAMM-PLLQEI 322
           L  LR+++  +  Q+  ++     + PLL EI
Sbjct: 411 LVSLRTLSSVHSEQVFALRLQDKKLPPLLSEI 442


>gi|63054845 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo
           sapiens]
          Length = 427

 Score =  124 bits (312), Expect = 9e-29
 Identities = 69/182 (37%), Positives = 107/182 (58%), Gaps = 7/182 (3%)

Query: 126 LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQT 185
           L ++ H AD+ ++ + +VI F K +P FR L  EDQI LLK +A+E+  +  N +F +  
Sbjct: 224 LSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDD 283

Query: 186 QNFLCG--PLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAP 243
            ++ CG    +Y + D  + G  +E +E L  F   L+KL L E E+VLL A+ + SP  
Sbjct: 284 MSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSP-- 341

Query: 244 YLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYG 303
              DRPGV     I+ +Q+ ++ TLQ+YI+ +   P    LYAK++  LA+LRS+NE + 
Sbjct: 342 ---DRPGVQDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHS 398

Query: 304 YQ 305
            Q
Sbjct: 399 KQ 400



 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 42/111 (37%), Positives = 65/111 (58%), Gaps = 5/111 (4%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR++ +    TCPF G C ++K  RRHC ACRL++C+D GM K+ IL+ E +  +R    
Sbjct: 49  RRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMIL 108

Query: 67  QRRAQQT-----PVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHL 112
           +R+ ++        +LS+EQ+ +I  LL AH +     +  F QFRPP  +
Sbjct: 109 KRKEEEALKDSLRPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRV 159


>gi|4507883 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo
           sapiens]
          Length = 427

 Score =  124 bits (312), Expect = 9e-29
 Identities = 69/182 (37%), Positives = 107/182 (58%), Gaps = 7/182 (3%)

Query: 126 LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQT 185
           L ++ H AD+ ++ + +VI F K +P FR L  EDQI LLK +A+E+  +  N +F +  
Sbjct: 224 LSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDD 283

Query: 186 QNFLCG--PLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAP 243
            ++ CG    +Y + D  + G  +E +E L  F   L+KL L E E+VLL A+ + SP  
Sbjct: 284 MSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSP-- 341

Query: 244 YLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYG 303
              DRPGV     I+ +Q+ ++ TLQ+YI+ +   P    LYAK++  LA+LRS+NE + 
Sbjct: 342 ---DRPGVQDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHS 398

Query: 304 YQ 305
            Q
Sbjct: 399 KQ 400



 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 42/111 (37%), Positives = 65/111 (58%), Gaps = 5/111 (4%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR++ +    TCPF G C ++K  RRHC ACRL++C+D GM K+ IL+ E +  +R    
Sbjct: 49  RRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMIL 108

Query: 67  QRRAQQT-----PVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHL 112
           +R+ ++        +LS+EQ+ +I  LL AH +     +  F QFRPP  +
Sbjct: 109 KRKEEEALKDSLRPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRV 159


>gi|85362735 nuclear receptor subfamily 1, group H, member 2 [Homo
           sapiens]
          Length = 461

 Score =  119 bits (299), Expect = 3e-27
 Identities = 94/350 (26%), Positives = 156/350 (44%), Gaps = 63/350 (18%)

Query: 18  CPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTP--- 74
           C   G+C++    RR C  CRL+KC +AGMR+  +LS E +  ++ ++ Q++  Q+    
Sbjct: 125 CRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQQESQSQSQS 184

Query: 75  ---------------------------------VQLSKEQEELIRTLLGAHTRHMGTMFE 101
                                            VQL+  QE +I+ L+ A  +     F 
Sbjct: 185 PVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFS 244

Query: 102 QFVQFRP------PAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRS 155
              +  P      P       Q             HF ++    V +++ F K +P F  
Sbjct: 245 DQPKVTPWPLGADPQSRDARQQRF----------AHFTELAIISVQEIVDFAKQVPGFLQ 294

Query: 156 LPIEDQISLLKGAAVEICHIVLNTTFCLQTQ--NFLCGPLRYTIEDGARVGFQVEFLELL 213
           L  EDQI+LLK + +EI  +     +  +T+   FL     Y+ +D  R G QVEF+  +
Sbjct: 295 LGREDQIALLKASTIEIMLLETARRYNHETECITFL-KDFTYSKDDFHRAGLQVEFINPI 353

Query: 214 FHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIK 273
           F F   +R+L L + EY LL A+ +FS      DRP V +   ++ LQ+     L SY +
Sbjct: 354 FEFSRAMRRLGLDDAEYALLIAINIFS-----ADRPNVQEPGRVEALQQPYVEALLSYTR 408

Query: 274 GQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMM-PLLQEI 322
              +RP+D+  + ++L  L  LR+++  +  Q+  ++     + PLL EI
Sbjct: 409 --IKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEI 456


>gi|189491771 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score =  112 bits (281), Expect = 3e-25
 Identities = 93/324 (28%), Positives = 148/324 (45%), Gaps = 32/324 (9%)

Query: 7   RRTVSKSIGPT--CPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAK 64
           RRT+ K++ P+  C + G C + K  R  C  CR +KC+  GM  D++L       +R  
Sbjct: 132 RRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKL 191

Query: 65  QAQRRAQQTPVQLSK----------EQEELIRTLLGAH--TRHMGTMFEQFVQFRPPAHL 112
             + R ++   +L K          E+ ELI+T+  AH  T   G+ ++Q  +F P    
Sbjct: 192 IEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPED-- 249

Query: 113 FIHHQPLPTLAPV-----LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKG 167
            I   P+   AP      L   +HF  I T  + +V+ F K LP+F  LP EDQI LLKG
Sbjct: 250 -IGQAPIVN-APEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKG 307

Query: 168 AAVEICHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQ 226
             +EI  +     +  +++   L G +  T       G  V   + +F    +L    L 
Sbjct: 308 CCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGV-VSDAIFDLGMSLSSFNLD 366

Query: 227 EPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYA 286
           + E  LL A+ L S     +DRPG+   + I++ Q+   L  + YI    R+      + 
Sbjct: 367 DTEVALLQAVLLMS-----SDRPGLACVERIEKYQDSFLLAFEHYI--NYRKHHVTHFWP 419

Query: 287 KLLGLLAELRSINEAYGYQIQHIQ 310
           KLL  + +LR I   +  +  H++
Sbjct: 420 KLLMKVTDLRMIGACHASRFLHMK 443


>gi|189491769 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score =  112 bits (281), Expect = 3e-25
 Identities = 93/324 (28%), Positives = 148/324 (45%), Gaps = 32/324 (9%)

Query: 7   RRTVSKSIGPT--CPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAK 64
           RRT+ K++ P+  C + G C + K  R  C  CR +KC+  GM  D++L       +R  
Sbjct: 132 RRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKL 191

Query: 65  QAQRRAQQTPVQLSK----------EQEELIRTLLGAH--TRHMGTMFEQFVQFRPPAHL 112
             + R ++   +L K          E+ ELI+T+  AH  T   G+ ++Q  +F P    
Sbjct: 192 IEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPED-- 249

Query: 113 FIHHQPLPTLAPV-----LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKG 167
            I   P+   AP      L   +HF  I T  + +V+ F K LP+F  LP EDQI LLKG
Sbjct: 250 -IGQAPIVN-APEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKG 307

Query: 168 AAVEICHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQ 226
             +EI  +     +  +++   L G +  T       G  V   + +F    +L    L 
Sbjct: 308 CCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGV-VSDAIFDLGMSLSSFNLD 366

Query: 227 EPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYA 286
           + E  LL A+ L S     +DRPG+   + I++ Q+   L  + YI    R+      + 
Sbjct: 367 DTEVALLQAVLLMS-----SDRPGLACVERIEKYQDSFLLAFEHYI--NYRKHHVTHFWP 419

Query: 287 KLLGLLAELRSINEAYGYQIQHIQ 310
           KLL  + +LR I   +  +  H++
Sbjct: 420 KLLMKVTDLRMIGACHASRFLHMK 443


>gi|40806162 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score =  112 bits (281), Expect = 3e-25
 Identities = 93/324 (28%), Positives = 148/324 (45%), Gaps = 32/324 (9%)

Query: 7   RRTVSKSIGPT--CPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAK 64
           RRT+ K++ P+  C + G C + K  R  C  CR +KC+  GM  D++L       +R  
Sbjct: 132 RRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKL 191

Query: 65  QAQRRAQQTPVQLSK----------EQEELIRTLLGAH--TRHMGTMFEQFVQFRPPAHL 112
             + R ++   +L K          E+ ELI+T+  AH  T   G+ ++Q  +F P    
Sbjct: 192 IEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPED-- 249

Query: 113 FIHHQPLPTLAPV-----LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKG 167
            I   P+   AP      L   +HF  I T  + +V+ F K LP+F  LP EDQI LLKG
Sbjct: 250 -IGQAPIVN-APEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKG 307

Query: 168 AAVEICHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQ 226
             +EI  +     +  +++   L G +  T       G  V   + +F    +L    L 
Sbjct: 308 CCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGV-VSDAIFDLGMSLSSFNLD 366

Query: 227 EPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYA 286
           + E  LL A+ L S     +DRPG+   + I++ Q+   L  + YI    R+      + 
Sbjct: 367 DTEVALLQAVLLMS-----SDRPGLACVERIEKYQDSFLLAFEHYI--NYRKHHVTHFWP 419

Query: 287 KLLGLLAELRSINEAYGYQIQHIQ 310
           KLL  + +LR I   +  +  H++
Sbjct: 420 KLLMKVTDLRMIGACHASRFLHMK 443


>gi|40806160 thyroid hormone receptor, alpha isoform 1 [Homo
           sapiens]
          Length = 410

 Score =  107 bits (266), Expect = 2e-23
 Identities = 91/323 (28%), Positives = 143/323 (44%), Gaps = 30/323 (9%)

Query: 7   RRTVSKSIGPT--CPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILS---------- 54
           RRT+ K++ PT  C +   C + K  R  C  CR +KC+  GM  D++L           
Sbjct: 78  RRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRKL 137

Query: 55  AEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAH--TRHMGTMFEQFVQFRPPAHL 112
            E    RR K+   R+ Q   + + E+ +LI     AH  T   G+ ++Q  +F P    
Sbjct: 138 IEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNAQGSHWKQRRKFLPDD-- 195

Query: 113 FIHHQPLPTLAPV----LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGA 168
            I   P+ ++       L   + F  I T  + +V+ F K LP+F  LP EDQI LLKG 
Sbjct: 196 -IGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIILLKGC 254

Query: 169 AVEICHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQE 227
            +EI  +     +  ++    L G +    E     G  V   + +F    +L    L +
Sbjct: 255 CMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGV-VSDAIFELGKSLSAFNLDD 313

Query: 228 PEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAK 287
            E  LL A+ L S     TDR G+   D+I++ QE   L  + Y+    R+      + K
Sbjct: 314 TEVALLQAVLLMS-----TDRSGLLCVDKIEKSQEAYLLAFEHYV--NHRKHNIPHFWPK 366

Query: 288 LLGLLAELRSINEAYGYQIQHIQ 310
           LL  + +LR I   +  +  H++
Sbjct: 367 LLMKVTDLRMIGACHASRFLHMK 389


>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
          Length = 462

 Score =  106 bits (264), Expect = 3e-23
 Identities = 90/323 (27%), Positives = 154/323 (47%), Gaps = 29/323 (8%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR++ K++  TC    +C ++K  R  C  CRLQKC + GM K+ + +      ++ K+ 
Sbjct: 113 RRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRN---KKKKEV 169

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
            +        L+ E  ELI  +  AH        E F           ++     ++  +
Sbjct: 170 PKPECSESYTLTPEVGELIEKVRKAHQ-------ETFPALCQLGKYTTNNSSEQRVSLDI 222

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQ-- 184
            L   F++++T  +++ ++F K LP F +L I DQI+LLK A ++I  + + T +  +  
Sbjct: 223 DLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQD 282

Query: 185 TQNFLCG-PLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAP 243
           T  F  G  L  T    A  G      +L+F F   L  L++ + E  LL+A+ L     
Sbjct: 283 TMTFSDGLTLNRTQMHNAGFG---PLTDLVFAFANQLLPLEMDDAETGLLSAICLI---- 335

Query: 244 YLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYG 303
              DR  + Q D +D LQE +   L+ Y++  +RRP    ++ K+L  + +LRSI+    
Sbjct: 336 -CGDRQDLEQPDRVDMLQEPLLEALKVYVR--KRRPSRPHMFPKMLMKITDLRSISAKGA 392

Query: 304 YQI----QHIQGLSAMMPLLQEI 322
            ++      I G  +M PL+QE+
Sbjct: 393 ERVITLKMEIPG--SMPPLIQEM 413


>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
          Length = 457

 Score =  106 bits (264), Expect = 3e-23
 Identities = 90/323 (27%), Positives = 154/323 (47%), Gaps = 29/323 (8%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR++ K++  TC    +C ++K  R  C  CRLQKC + GM K+ + +      ++ K+ 
Sbjct: 108 RRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRN---KKKKEV 164

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
            +        L+ E  ELI  +  AH        E F           ++     ++  +
Sbjct: 165 PKPECSESYTLTPEVGELIEKVRKAHQ-------ETFPALCQLGKYTTNNSSEQRVSLDI 217

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQ-- 184
            L   F++++T  +++ ++F K LP F +L I DQI+LLK A ++I  + + T +  +  
Sbjct: 218 DLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQD 277

Query: 185 TQNFLCG-PLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAP 243
           T  F  G  L  T    A  G      +L+F F   L  L++ + E  LL+A+ L     
Sbjct: 278 TMTFSDGLTLNRTQMHNAGFG---PLTDLVFAFANQLLPLEMDDAETGLLSAICLI---- 330

Query: 244 YLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYG 303
              DR  + Q D +D LQE +   L+ Y++  +RRP    ++ K+L  + +LRSI+    
Sbjct: 331 -CGDRQDLEQPDRVDMLQEPLLEALKVYVR--KRRPSRPHMFPKMLMKITDLRSISAKGA 387

Query: 304 YQI----QHIQGLSAMMPLLQEI 322
            ++      I G  +M PL+QE+
Sbjct: 388 ERVITLKMEIPG--SMPPLIQEM 408


>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
          Length = 462

 Score =  106 bits (264), Expect = 3e-23
 Identities = 90/323 (27%), Positives = 154/323 (47%), Gaps = 29/323 (8%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR++ K++  TC    +C ++K  R  C  CRLQKC + GM K+ + +      ++ K+ 
Sbjct: 113 RRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRN---KKKKEV 169

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
            +        L+ E  ELI  +  AH        E F           ++     ++  +
Sbjct: 170 PKPECSESYTLTPEVGELIEKVRKAHQ-------ETFPALCQLGKYTTNNSSEQRVSLDI 222

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQ-- 184
            L   F++++T  +++ ++F K LP F +L I DQI+LLK A ++I  + + T +  +  
Sbjct: 223 DLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQD 282

Query: 185 TQNFLCG-PLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAP 243
           T  F  G  L  T    A  G      +L+F F   L  L++ + E  LL+A+ L     
Sbjct: 283 TMTFSDGLTLNRTQMHNAGFG---PLTDLVFAFANQLLPLEMDDAETGLLSAICLI---- 335

Query: 244 YLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYG 303
              DR  + Q D +D LQE +   L+ Y++  +RRP    ++ K+L  + +LRSI+    
Sbjct: 336 -CGDRQDLEQPDRVDMLQEPLLEALKVYVR--KRRPSRPHMFPKMLMKITDLRSISAKGA 392

Query: 304 YQI----QHIQGLSAMMPLLQEI 322
            ++      I G  +M PL+QE+
Sbjct: 393 ERVITLKMEIPG--SMPPLIQEM 413


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.139    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,708,765
Number of Sequences: 37866
Number of extensions: 503236
Number of successful extensions: 2149
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 113
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 1827
Number of HSP's gapped (non-prelim): 200
length of query: 324
length of database: 18,247,518
effective HSP length: 102
effective length of query: 222
effective length of database: 14,385,186
effective search space: 3193511292
effective search space used: 3193511292
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.