Guide to the Human Genome
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Search of human proteins with 117938732

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|117938732 constitutive androstane receptor isoform 11 [Homo
sapiens]
         (280 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|117938732 constitutive androstane receptor isoform 11 [Homo s...   561   e-160
gi|117938734 constitutive androstane receptor isoform 5 [Homo sa...   550   e-157
gi|117938754 constitutive androstane receptor isoform 4 [Homo sa...   544   e-155
gi|117938750 constitutive androstane receptor isoform 10 [Homo s...   542   e-154
gi|117938736 constitutive androstane receptor isoform 9 [Homo sa...   540   e-154
gi|4826661 constitutive androstane receptor isoform 3 [Homo sapi...   531   e-151
gi|117938752 constitutive androstane receptor isoform 2 [Homo sa...   529   e-151
gi|117938756 constitutive androstane receptor isoform 1 [Homo sa...   527   e-150
gi|117938742 constitutive androstane receptor isoform 15 [Homo s...   481   e-136
gi|117938740 constitutive androstane receptor isoform 8 [Homo sa...   469   e-132
gi|117938748 constitutive androstane receptor isoform 14 [Homo s...   461   e-130
gi|117938744 constitutive androstane receptor isoform 13 [Homo s...   459   e-130
gi|117938738 constitutive androstane receptor isoform 12 [Homo s...   458   e-129
gi|117938746 constitutive androstane receptor isoform 7 [Homo sa...   448   e-126
gi|117938729 constitutive androstane receptor isoform 6 [Homo sa...   448   e-126
gi|14702164 nuclear receptor subfamily 1, group I, member 2 isof...   193   2e-49
gi|11863132 nuclear receptor subfamily 1, group I, member 2 isof...   181   5e-46
gi|34398348 nuclear receptor subfamily 1, group I, member 2 isof...   181   5e-46
gi|189491771 thyroid hormone receptor, beta [Homo sapiens]             94   1e-19
gi|189491769 thyroid hormone receptor, beta [Homo sapiens]             94   1e-19
gi|40806162 thyroid hormone receptor, beta [Homo sapiens]              94   1e-19
gi|194294519 nuclear receptor subfamily 1, group H, member 3 iso...    90   3e-18
gi|194294517 nuclear receptor subfamily 1, group H, member 3 iso...    90   3e-18
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]    88   1e-17
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]     88   1e-17
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]      88   1e-17
gi|63054845 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo ...    87   1e-17
gi|4507883 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo s...    87   1e-17
gi|40806160 thyroid hormone receptor, alpha isoform 1 [Homo sapi...    86   3e-17
gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]    84   1e-16

>gi|117938732 constitutive androstane receptor isoform 11 [Homo
           sapiens]
          Length = 280

 Score =  561 bits (1447), Expect = e-160
 Identities = 280/280 (100%), Positives = 280/280 (100%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFL 240
           FCLQTQNFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFL
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFL 240

Query: 241 YAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 280
           YAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 241 YAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 280


>gi|117938734 constitutive androstane receptor isoform 5 [Homo
           sapiens]
          Length = 309

 Score =  550 bits (1417), Expect = e-157
 Identities = 274/274 (100%), Positives = 274/274 (100%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLG 246
           NFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLG
Sbjct: 216 NFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLG 275

Query: 247 LLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 280
           LLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 276 LLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 309


>gi|117938754 constitutive androstane receptor isoform 4 [Homo
           sapiens]
          Length = 314

 Score =  544 bits (1401), Expect = e-155
 Identities = 274/279 (98%), Positives = 274/279 (98%), Gaps = 5/279 (1%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGAR-----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLY 241
           NFLCGPLRYTIEDGAR     DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLY
Sbjct: 216 NFLCGPLRYTIEDGARAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLY 275

Query: 242 AKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 280
           AKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 276 AKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 314


>gi|117938750 constitutive androstane receptor isoform 10 [Homo
           sapiens]
          Length = 319

 Score =  542 bits (1397), Expect = e-154
 Identities = 280/319 (87%), Positives = 280/319 (87%), Gaps = 39/319 (12%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGAR-------------------------------------- 202
           FCLQTQNFLCGPLRYTIEDGAR                                      
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240

Query: 203 -DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQ 261
            DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQ
Sbjct: 241 PDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQ 300

Query: 262 IQHIQGLSAMMPLLQEICS 280
           IQHIQGLSAMMPLLQEICS
Sbjct: 301 IQHIQGLSAMMPLLQEICS 319


>gi|117938736 constitutive androstane receptor isoform 9 [Homo
           sapiens]
          Length = 324

 Score =  540 bits (1392), Expect = e-154
 Identities = 280/324 (86%), Positives = 280/324 (86%), Gaps = 44/324 (13%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGAR-------------------------------------- 202
           FCLQTQNFLCGPLRYTIEDGAR                                      
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240

Query: 203 ------DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINE 256
                 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINE
Sbjct: 241 PAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINE 300

Query: 257 AYGYQIQHIQGLSAMMPLLQEICS 280
           AYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 301 AYGYQIQHIQGLSAMMPLLQEICS 324


>gi|4826661 constitutive androstane receptor isoform 3 [Homo
           sapiens]
          Length = 348

 Score =  531 bits (1367), Expect = e-151
 Identities = 274/313 (87%), Positives = 274/313 (87%), Gaps = 39/313 (12%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGAR---------------------------------------DRPGV 207
           NFLCGPLRYTIEDGAR                                       DRPGV
Sbjct: 216 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGV 275

Query: 208 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQG 267
           TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQG
Sbjct: 276 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQG 335

Query: 268 LSAMMPLLQEICS 280
           LSAMMPLLQEICS
Sbjct: 336 LSAMMPLLQEICS 348


>gi|117938752 constitutive androstane receptor isoform 2 [Homo
           sapiens]
          Length = 352

 Score =  529 bits (1363), Expect = e-151
 Identities = 274/317 (86%), Positives = 274/317 (86%), Gaps = 43/317 (13%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGAR-------------------------------------------D 203
           NFLCGPLRYTIEDGAR                                           D
Sbjct: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD 275

Query: 204 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQ 263
           RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQ
Sbjct: 276 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQ 335

Query: 264 HIQGLSAMMPLLQEICS 280
           HIQGLSAMMPLLQEICS
Sbjct: 336 HIQGLSAMMPLLQEICS 352


>gi|117938756 constitutive androstane receptor isoform 1 [Homo
           sapiens]
          Length = 357

 Score =  527 bits (1358), Expect = e-150
 Identities = 274/322 (85%), Positives = 274/322 (85%), Gaps = 48/322 (14%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGAR-------------------------------------------- 202
           NFLCGPLRYTIEDGAR                                            
Sbjct: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 275

Query: 203 ----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAY 258
               DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAY
Sbjct: 276 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAY 335

Query: 259 GYQIQHIQGLSAMMPLLQEICS 280
           GYQIQHIQGLSAMMPLLQEICS
Sbjct: 336 GYQIQHIQGLSAMMPLLQEICS 357


>gi|117938742 constitutive androstane receptor isoform 15 [Homo
           sapiens]
          Length = 267

 Score =  481 bits (1237), Expect = e-136
 Identities = 238/238 (100%), Positives = 238/238 (100%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238
           FCLQTQNFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238


>gi|117938740 constitutive androstane receptor isoform 8 [Homo
           sapiens]
          Length = 296

 Score =  469 bits (1207), Expect = e-132
 Identities = 232/232 (100%), Positives = 232/232 (100%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238
           NFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 216 NFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 267


>gi|117938748 constitutive androstane receptor isoform 14 [Homo
           sapiens]
          Length = 306

 Score =  461 bits (1187), Expect = e-130
 Identities = 238/277 (85%), Positives = 238/277 (85%), Gaps = 39/277 (14%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGAR-------------------------------------- 202
           FCLQTQNFLCGPLRYTIEDGAR                                      
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240

Query: 203 -DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238
            DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 241 PDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277


>gi|117938744 constitutive androstane receptor isoform 13 [Homo
           sapiens]
          Length = 311

 Score =  459 bits (1182), Expect = e-130
 Identities = 238/282 (84%), Positives = 238/282 (84%), Gaps = 44/282 (15%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGAR-------------------------------------- 202
           FCLQTQNFLCGPLRYTIEDGAR                                      
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240

Query: 203 ------DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238
                 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 241 PAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 282


>gi|117938738 constitutive androstane receptor isoform 12 [Homo
           sapiens]
          Length = 315

 Score =  458 bits (1178), Expect = e-129
 Identities = 238/286 (83%), Positives = 238/286 (83%), Gaps = 48/286 (16%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGAR-------------------------------------- 202
           FCLQTQNFLCGPLRYTIEDGAR                                      
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAM 240

Query: 203 ----------DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238
                     DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 241 ALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 286


>gi|117938746 constitutive androstane receptor isoform 7 [Homo
           sapiens]
          Length = 339

 Score =  448 bits (1153), Expect = e-126
 Identities = 232/275 (84%), Positives = 232/275 (84%), Gaps = 43/275 (15%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGAR-------------------------------------------D 203
           NFLCGPLRYTIEDGAR                                           D
Sbjct: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD 275

Query: 204 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238
           RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 276 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 310


>gi|117938729 constitutive androstane receptor isoform 6 [Homo
           sapiens]
          Length = 340

 Score =  448 bits (1152), Expect = e-126
 Identities = 232/276 (84%), Positives = 232/276 (84%), Gaps = 44/276 (15%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGAR-------------------------------------------- 202
           NFLCGPLRYTIEDGAR                                            
Sbjct: 216 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLT 275

Query: 203 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238
           DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 276 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 311


>gi|14702164 nuclear receptor subfamily 1, group I, member 2 isoform
           3 [Homo sapiens]
          Length = 397

 Score =  193 bits (490), Expect = 2e-49
 Identities = 118/326 (36%), Positives = 173/326 (53%), Gaps = 54/326 (16%)

Query: 7   RRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQ 65
           RR + ++    CPF  G+CE+++  RR C ACRL+KCL++GM+K+MI+S EA+  RRA  
Sbjct: 66  RRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALI 125

Query: 66  AQRRAQQTPVQ------LSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPL 119
            ++++++T  Q      L++EQ  +IR L+ A  +   T F  F  FR    L      +
Sbjct: 126 KRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRVSLQLRGEDGSV 185

Query: 120 PTLAP--------VLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVE 171
               P        +  L+ H AD++T+M   +I F K +  FR LPIEDQISLLKGAA E
Sbjct: 186 WNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFE 245

Query: 172 ICHIVLNTTFCLQTQNFLCGPLRYTIEDGA------------------------------ 201
           +C +  NT F  +T  + CG L Y +ED A                              
Sbjct: 246 LCQLRFNTVFNAETGTWECGRLSYCLEDTAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVL 305

Query: 202 --------RDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRS 253
                    DRPGV Q   +DQLQE+ A+TL+SYI+  + +P  RFL+ K++ +L ELRS
Sbjct: 306 MQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRS 365

Query: 254 INEAYGYQIQHIQGLSAM-MPLLQEI 278
           IN  +  ++  IQ +     PL+QE+
Sbjct: 366 INAQHTQRLLRIQDIHPFATPLMQEL 391


>gi|11863132 nuclear receptor subfamily 1, group I, member 2 isoform
           2 [Homo sapiens]
          Length = 473

 Score =  181 bits (460), Expect = 5e-46
 Identities = 121/363 (33%), Positives = 176/363 (48%), Gaps = 91/363 (25%)

Query: 7   RRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQ 65
           RR + ++    CPF  G+CE+++  RR C ACRL+KCL++GM+K+MI+S EA+  RRA  
Sbjct: 105 RRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALI 164

Query: 66  AQRRAQQTPVQ------LSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQ-P 118
            ++++++T  Q      L++EQ  +IR L+ A  +   T F  F  FR P  L    + P
Sbjct: 165 KRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGCELP 224

Query: 119 LPTLAP--------------------------------------------VLPLVTHFAD 134
               AP                                            +  L+ H AD
Sbjct: 225 ESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMAD 284

Query: 135 INTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLR 194
           ++T+M   +I F K +  FR LPIEDQISLLKGAA E+C +  NT F  +T  + CG L 
Sbjct: 285 MSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLS 344

Query: 195 YTIEDGA--------------------------------------RDRPGVTQRDEIDQL 216
           Y +ED A                                       DRPGV Q   +DQL
Sbjct: 345 YCLEDTAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQL 404

Query: 217 QEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAM-MPLL 275
           QE+ A+TL+SYI+  + +P  RFL+ K++ +L ELRSIN  +  ++  IQ +     PL+
Sbjct: 405 QEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLM 464

Query: 276 QEI 278
           QE+
Sbjct: 465 QEL 467


>gi|34398348 nuclear receptor subfamily 1, group I, member 2 isoform
           1 [Homo sapiens]
          Length = 434

 Score =  181 bits (460), Expect = 5e-46
 Identities = 121/363 (33%), Positives = 176/363 (48%), Gaps = 91/363 (25%)

Query: 7   RRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQ 65
           RR + ++    CPF  G+CE+++  RR C ACRL+KCL++GM+K+MI+S EA+  RRA  
Sbjct: 66  RRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALI 125

Query: 66  AQRRAQQTPVQ------LSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQ-P 118
            ++++++T  Q      L++EQ  +IR L+ A  +   T F  F  FR P  L    + P
Sbjct: 126 KRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGCELP 185

Query: 119 LPTLAP--------------------------------------------VLPLVTHFAD 134
               AP                                            +  L+ H AD
Sbjct: 186 ESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMAD 245

Query: 135 INTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLR 194
           ++T+M   +I F K +  FR LPIEDQISLLKGAA E+C +  NT F  +T  + CG L 
Sbjct: 246 MSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLS 305

Query: 195 YTIEDGA--------------------------------------RDRPGVTQRDEIDQL 216
           Y +ED A                                       DRPGV Q   +DQL
Sbjct: 306 YCLEDTAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQL 365

Query: 217 QEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAM-MPLL 275
           QE+ A+TL+SYI+  + +P  RFL+ K++ +L ELRSIN  +  ++  IQ +     PL+
Sbjct: 366 QEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLM 425

Query: 276 QEI 278
           QE+
Sbjct: 426 QEL 428


>gi|189491771 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score = 94.0 bits (232), Expect = 1e-19
 Identities = 84/318 (26%), Positives = 133/318 (41%), Gaps = 64/318 (20%)

Query: 7   RRTVSKSIGPT--CPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAK 64
           RRT+ K++ P+  C + G C + K  R  C  CR +KC+  GM  D++L       +R  
Sbjct: 132 RRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKL 191

Query: 65  QAQRRAQQTPVQLSK----------EQEELIRTLLGAH--TRHMGTMFEQFVQFRPPAHL 112
             + R ++   +L K          E+ ELI+T+  AH  T   G+ ++Q  +F P    
Sbjct: 192 IEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPED-- 249

Query: 113 FIHHQPLPTLAPV-----LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKG 167
            I   P+   AP      L   +HF  I T  + +V+ F K LP+F  LP EDQI LLKG
Sbjct: 250 -IGQAPIVN-APEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKG 307

Query: 168 AAVEICH-------------IVLNTTFCLQTQNFLCGPL---------------RYTIED 199
             +EI               + LN    +       G L                + ++D
Sbjct: 308 CCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDD 367

Query: 200 G-----------ARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLL 248
                       + DRPG+   + I++ Q+   L  + YI    R+      + KLL  +
Sbjct: 368 TEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYI--NYRKHHVTHFWPKLLMKV 425

Query: 249 AELRSINEAYGYQIQHIQ 266
            +LR I   +  +  H++
Sbjct: 426 TDLRMIGACHASRFLHMK 443


>gi|189491769 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score = 94.0 bits (232), Expect = 1e-19
 Identities = 84/318 (26%), Positives = 133/318 (41%), Gaps = 64/318 (20%)

Query: 7   RRTVSKSIGPT--CPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAK 64
           RRT+ K++ P+  C + G C + K  R  C  CR +KC+  GM  D++L       +R  
Sbjct: 132 RRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKL 191

Query: 65  QAQRRAQQTPVQLSK----------EQEELIRTLLGAH--TRHMGTMFEQFVQFRPPAHL 112
             + R ++   +L K          E+ ELI+T+  AH  T   G+ ++Q  +F P    
Sbjct: 192 IEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPED-- 249

Query: 113 FIHHQPLPTLAPV-----LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKG 167
            I   P+   AP      L   +HF  I T  + +V+ F K LP+F  LP EDQI LLKG
Sbjct: 250 -IGQAPIVN-APEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKG 307

Query: 168 AAVEICH-------------IVLNTTFCLQTQNFLCGPL---------------RYTIED 199
             +EI               + LN    +       G L                + ++D
Sbjct: 308 CCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDD 367

Query: 200 G-----------ARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLL 248
                       + DRPG+   + I++ Q+   L  + YI    R+      + KLL  +
Sbjct: 368 TEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYI--NYRKHHVTHFWPKLLMKV 425

Query: 249 AELRSINEAYGYQIQHIQ 266
            +LR I   +  +  H++
Sbjct: 426 TDLRMIGACHASRFLHMK 443


>gi|40806162 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score = 94.0 bits (232), Expect = 1e-19
 Identities = 84/318 (26%), Positives = 133/318 (41%), Gaps = 64/318 (20%)

Query: 7   RRTVSKSIGPT--CPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAK 64
           RRT+ K++ P+  C + G C + K  R  C  CR +KC+  GM  D++L       +R  
Sbjct: 132 RRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKL 191

Query: 65  QAQRRAQQTPVQLSK----------EQEELIRTLLGAH--TRHMGTMFEQFVQFRPPAHL 112
             + R ++   +L K          E+ ELI+T+  AH  T   G+ ++Q  +F P    
Sbjct: 192 IEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPED-- 249

Query: 113 FIHHQPLPTLAPV-----LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKG 167
            I   P+   AP      L   +HF  I T  + +V+ F K LP+F  LP EDQI LLKG
Sbjct: 250 -IGQAPIVN-APEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKG 307

Query: 168 AAVEICH-------------IVLNTTFCLQTQNFLCGPL---------------RYTIED 199
             +EI               + LN    +       G L                + ++D
Sbjct: 308 CCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDD 367

Query: 200 G-----------ARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLL 248
                       + DRPG+   + I++ Q+   L  + YI    R+      + KLL  +
Sbjct: 368 TEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYI--NYRKHHVTHFWPKLLMKV 425

Query: 249 AELRSINEAYGYQIQHIQ 266
            +LR I   +  +  H++
Sbjct: 426 TDLRMIGACHASRFLHMK 443


>gi|194294519 nuclear receptor subfamily 1, group H, member 3
           isoform c [Homo sapiens]
          Length = 402

 Score = 89.7 bits (221), Expect = 3e-18
 Identities = 82/327 (25%), Positives = 134/327 (40%), Gaps = 62/327 (18%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR+V K     C   G C +    RR C  CRL+KC  AGMR++ +LS E + L++ K+ 
Sbjct: 78  RRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQ 137

Query: 67  QR----------RAQQTP---VQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRP-PAHL 112
           +           RA   P    QLS EQ  +I  L+ A  +     F   ++  P P   
Sbjct: 138 EEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAP 197

Query: 113 FIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEI 172
             H +             HF ++    V +++ F K LP F  L  EDQI+LLK +A+E+
Sbjct: 198 DPHSREARQ-----QRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEV 252

Query: 173 CHIVLNTTFCLQTQNF-LCGPLRYTIEDGAR----------------------------- 202
             +  +  +   +++        Y  ED A+                             
Sbjct: 253 MLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFA 312

Query: 203 ----------DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELR 252
                     DRP V  + ++++LQ      L +Y+      P DR ++ ++L  L  LR
Sbjct: 313 LLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYV--SIHHPHDRLMFPRMLMKLVSLR 370

Query: 253 SINEAYGYQIQHIQGLSAMM-PLLQEI 278
           +++  +  Q+  ++     + PLL EI
Sbjct: 371 TLSSVHSEQVFALRLQDKKLPPLLSEI 397


>gi|194294517 nuclear receptor subfamily 1, group H, member 3
           isoform a [Homo sapiens]
          Length = 447

 Score = 89.7 bits (221), Expect = 3e-18
 Identities = 82/327 (25%), Positives = 134/327 (40%), Gaps = 62/327 (18%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR+V K     C   G C +    RR C  CRL+KC  AGMR++ +LS E + L++ K+ 
Sbjct: 123 RRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQ 182

Query: 67  QR----------RAQQTP---VQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRP-PAHL 112
           +           RA   P    QLS EQ  +I  L+ A  +     F   ++  P P   
Sbjct: 183 EEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAP 242

Query: 113 FIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEI 172
             H +             HF ++    V +++ F K LP F  L  EDQI+LLK +A+E+
Sbjct: 243 DPHSREARQ-----QRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEV 297

Query: 173 CHIVLNTTFCLQTQNF-LCGPLRYTIEDGAR----------------------------- 202
             +  +  +   +++        Y  ED A+                             
Sbjct: 298 MLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFA 357

Query: 203 ----------DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELR 252
                     DRP V  + ++++LQ      L +Y+      P DR ++ ++L  L  LR
Sbjct: 358 LLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYV--SIHHPHDRLMFPRMLMKLVSLR 415

Query: 253 SINEAYGYQIQHIQGLSAMM-PLLQEI 278
           +++  +  Q+  ++     + PLL EI
Sbjct: 416 TLSSVHSEQVFALRLQDKKLPPLLSEI 442


>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
          Length = 462

 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 80/315 (25%), Positives = 137/315 (43%), Gaps = 57/315 (18%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR++ K++  TC    +C ++K  R  C  CRLQKC + GM K+ + +      ++ K+ 
Sbjct: 113 RRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRN---KKKKEV 169

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
            +        L+ E  ELI  +  AH        E F           ++     ++  +
Sbjct: 170 PKPECSESYTLTPEVGELIEKVRKAHQ-------ETFPALCQLGKYTTNNSSEQRVSLDI 222

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFC---- 182
            L   F++++T  +++ ++F K LP F +L I DQI+LLK A ++I  + + T +     
Sbjct: 223 DLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQD 282

Query: 183 ------------LQTQNFLCGPLRYTI---------------EDG--------ARDRPGV 207
                        Q  N   GPL   +               E G          DR  +
Sbjct: 283 TMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDL 342

Query: 208 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQI----Q 263
            Q D +D LQE +   L+ Y++  +RRP    ++ K+L  + +LRSI+     ++     
Sbjct: 343 EQPDRVDMLQEPLLEALKVYVR--KRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKM 400

Query: 264 HIQGLSAMMPLLQEI 278
            I G  +M PL+QE+
Sbjct: 401 EIPG--SMPPLIQEM 413


>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
          Length = 457

 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 80/315 (25%), Positives = 137/315 (43%), Gaps = 57/315 (18%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR++ K++  TC    +C ++K  R  C  CRLQKC + GM K+ + +      ++ K+ 
Sbjct: 108 RRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRN---KKKKEV 164

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
            +        L+ E  ELI  +  AH        E F           ++     ++  +
Sbjct: 165 PKPECSESYTLTPEVGELIEKVRKAHQ-------ETFPALCQLGKYTTNNSSEQRVSLDI 217

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFC---- 182
            L   F++++T  +++ ++F K LP F +L I DQI+LLK A ++I  + + T +     
Sbjct: 218 DLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQD 277

Query: 183 ------------LQTQNFLCGPLRYTI---------------EDG--------ARDRPGV 207
                        Q  N   GPL   +               E G          DR  +
Sbjct: 278 TMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDL 337

Query: 208 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQI----Q 263
            Q D +D LQE +   L+ Y++  +RRP    ++ K+L  + +LRSI+     ++     
Sbjct: 338 EQPDRVDMLQEPLLEALKVYVR--KRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKM 395

Query: 264 HIQGLSAMMPLLQEI 278
            I G  +M PL+QE+
Sbjct: 396 EIPG--SMPPLIQEM 408


>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
          Length = 462

 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 80/315 (25%), Positives = 137/315 (43%), Gaps = 57/315 (18%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR++ K++  TC    +C ++K  R  C  CRLQKC + GM K+ + +      ++ K+ 
Sbjct: 113 RRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRN---KKKKEV 169

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
            +        L+ E  ELI  +  AH        E F           ++     ++  +
Sbjct: 170 PKPECSESYTLTPEVGELIEKVRKAHQ-------ETFPALCQLGKYTTNNSSEQRVSLDI 222

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFC---- 182
            L   F++++T  +++ ++F K LP F +L I DQI+LLK A ++I  + + T +     
Sbjct: 223 DLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQD 282

Query: 183 ------------LQTQNFLCGPLRYTI---------------EDG--------ARDRPGV 207
                        Q  N   GPL   +               E G          DR  +
Sbjct: 283 TMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDL 342

Query: 208 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQI----Q 263
            Q D +D LQE +   L+ Y++  +RRP    ++ K+L  + +LRSI+     ++     
Sbjct: 343 EQPDRVDMLQEPLLEALKVYVR--KRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKM 400

Query: 264 HIQGLSAMMPLLQEI 278
            I G  +M PL+QE+
Sbjct: 401 EIPG--SMPPLIQEM 413


>gi|63054845 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo
           sapiens]
          Length = 427

 Score = 87.4 bits (215), Expect = 1e-17
 Identities = 42/111 (37%), Positives = 65/111 (58%), Gaps = 5/111 (4%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR++ +    TCPF G C ++K  RRHC ACRL++C+D GM K+ IL+ E +  +R    
Sbjct: 49  RRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMIL 108

Query: 67  QRRAQQT-----PVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHL 112
           +R+ ++        +LS+EQ+ +I  LL AH +     +  F QFRPP  +
Sbjct: 109 KRKEEEALKDSLRPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRV 159



 Score = 82.0 bits (201), Expect = 5e-16
 Identities = 52/177 (29%), Positives = 84/177 (47%), Gaps = 41/177 (23%)

Query: 126 LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQT 185
           L ++ H AD+ ++ + +VI F K +P FR L  EDQI LLK +A+E+  +  N +F +  
Sbjct: 224 LSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDD 283

Query: 186 QNFLCG--PLRYTIEDGAR---------------------------------------DR 204
            ++ CG    +Y + D  +                                       DR
Sbjct: 284 MSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDR 343

Query: 205 PGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQ 261
           PGV     I+ +Q+ ++ TLQ+YI+ +   P    LYAK++  LA+LRS+NE +  Q
Sbjct: 344 PGVQDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQ 400


>gi|4507883 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo
           sapiens]
          Length = 427

 Score = 87.4 bits (215), Expect = 1e-17
 Identities = 42/111 (37%), Positives = 65/111 (58%), Gaps = 5/111 (4%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR++ +    TCPF G C ++K  RRHC ACRL++C+D GM K+ IL+ E +  +R    
Sbjct: 49  RRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMIL 108

Query: 67  QRRAQQT-----PVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHL 112
           +R+ ++        +LS+EQ+ +I  LL AH +     +  F QFRPP  +
Sbjct: 109 KRKEEEALKDSLRPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRV 159



 Score = 82.0 bits (201), Expect = 5e-16
 Identities = 52/177 (29%), Positives = 84/177 (47%), Gaps = 41/177 (23%)

Query: 126 LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQT 185
           L ++ H AD+ ++ + +VI F K +P FR L  EDQI LLK +A+E+  +  N +F +  
Sbjct: 224 LSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDD 283

Query: 186 QNFLCG--PLRYTIEDGAR---------------------------------------DR 204
            ++ CG    +Y + D  +                                       DR
Sbjct: 284 MSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDR 343

Query: 205 PGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQ 261
           PGV     I+ +Q+ ++ TLQ+YI+ +   P    LYAK++  LA+LRS+NE +  Q
Sbjct: 344 PGVQDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQ 400


>gi|40806160 thyroid hormone receptor, alpha isoform 1 [Homo
           sapiens]
          Length = 410

 Score = 86.3 bits (212), Expect = 3e-17
 Identities = 80/317 (25%), Positives = 131/317 (41%), Gaps = 62/317 (19%)

Query: 7   RRTVSKSIGPT--CPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILS---------- 54
           RRT+ K++ PT  C +   C + K  R  C  CR +KC+  GM  D++L           
Sbjct: 78  RRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRKL 137

Query: 55  AEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAH--TRHMGTMFEQFVQFRPPAHL 112
            E    RR K+   R+ Q   + + E+ +LI     AH  T   G+ ++Q  +F P    
Sbjct: 138 IEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNAQGSHWKQRRKFLPDD-- 195

Query: 113 FIHHQPLPTLAPV----LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGA 168
            I   P+ ++       L   + F  I T  + +V+ F K LP+F  LP EDQI LLKG 
Sbjct: 196 -IGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIILLKGC 254

Query: 169 AVEICH-------------IVLNTTFCLQTQNFLCGPL---------------RYTIEDG 200
            +EI               + L+    ++ +    G L                + ++D 
Sbjct: 255 CMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAIFELGKSLSAFNLDDT 314

Query: 201 -----------ARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLA 249
                      + DR G+   D+I++ QE   L  + Y+    R+      + KLL  + 
Sbjct: 315 EVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYV--NHRKHNIPHFWPKLLMKVT 372

Query: 250 ELRSINEAYGYQIQHIQ 266
           +LR I   +  +  H++
Sbjct: 373 DLRMIGACHASRFLHMK 389


>gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]
          Length = 443

 Score = 84.3 bits (207), Expect = 1e-16
 Identities = 71/288 (24%), Positives = 125/288 (43%), Gaps = 51/288 (17%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR++ K++  TC    +C ++K  R  C  CRLQKC + GM K+ + +      ++ K+ 
Sbjct: 104 RRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRN---KKKKEV 160

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           +        +LS + EELI  +  AH        E F           +      +   L
Sbjct: 161 KEEGSPDSYELSPQLEELITKVSKAHQ-------ETFPSLCQLGKYTTNSSADHRVQLDL 213

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFC---- 182
            L   F+++ T  ++++++F K LP F  L I DQI+LLK A ++I  + + T +     
Sbjct: 214 GLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQD 273

Query: 183 ------------LQTQNFLCGPLRYTI---------------EDG--------ARDRPGV 207
                        Q  N   GPL   +               E G          DR  +
Sbjct: 274 TMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDL 333

Query: 208 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSIN 255
            + +++D+LQE +   L+ Y   ++RRP   +++ ++L  + +LR I+
Sbjct: 334 EEPEKVDKLQEPLLEALRLY--ARRRRPSQPYMFPRMLMKITDLRGIS 379


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.138    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,112,548
Number of Sequences: 37866
Number of extensions: 431232
Number of successful extensions: 1967
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 117
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 1688
Number of HSP's gapped (non-prelim): 242
length of query: 280
length of database: 18,247,518
effective HSP length: 101
effective length of query: 179
effective length of database: 14,423,052
effective search space: 2581726308
effective search space used: 2581726308
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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