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Search of human proteins with 117676384
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|117676384 splicing factor, arginine/serine-rich 2,
interacting protein [Homo sapiens]
(1463 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|117676384 splicing factor, arginine/serine-rich 2, interactin... 2961 0.0
gi|221139764 PHD and ring finger domains 1 [Homo sapiens] 128 5e-29
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 124 7e-28
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 89 4e-17
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 88 5e-17
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 87 9e-17
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 87 9e-17
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 86 2e-16
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 84 8e-16
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 83 2e-15
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 82 4e-15
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 80 1e-14
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 80 1e-14
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 78 7e-14
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 76 2e-13
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 76 2e-13
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 76 2e-13
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 76 3e-13
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 75 4e-13
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 75 4e-13
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 75 5e-13
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 75 5e-13
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 75 5e-13
gi|52426743 cisplatin resistance-associated overexpressed protei... 74 1e-12
gi|19923485 cisplatin resistance-associated overexpressed protei... 74 1e-12
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] 73 2e-12
gi|153251865 hypothetical protein LOC84226 [Homo sapiens] 73 2e-12
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 73 2e-12
gi|150170670 piccolo isoform 2 [Homo sapiens] 71 7e-12
gi|150378539 piccolo isoform 1 [Homo sapiens] 71 7e-12
>gi|117676384 splicing factor, arginine/serine-rich 2, interacting
protein [Homo sapiens]
Length = 1463
Score = 2961 bits (7677), Expect = 0.0
Identities = 1463/1463 (100%), Positives = 1463/1463 (100%)
Query: 1 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN 60
MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN
Sbjct: 1 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN 60
Query: 61 HVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETKDKKNENSFEK 120
HVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETKDKKNENSFEK
Sbjct: 61 HVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETKDKKNENSFEK 120
Query: 121 QVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAIKINKPQRSNW 180
QVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAIKINKPQRSNW
Sbjct: 121 QVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAIKINKPQRSNW 180
Query: 181 STNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHELELSWFPDTL 240
STNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHELELSWFPDTL
Sbjct: 181 STNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHELELSWFPDTL 240
Query: 241 PGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALAHTQEGEEKKQ 300
PGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALAHTQEGEEKKQ
Sbjct: 241 PGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALAHTQEGEEKKQ 300
Query: 301 TSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNSNPSLSVPS 360
TSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNSNPSLSVPS
Sbjct: 301 TSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNSNPSLSVPS 360
Query: 361 SAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAESDTSPVLE 420
SAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAESDTSPVLE
Sbjct: 361 SAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAESDTSPVLE 420
Query: 421 KEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERVGSSSSESCAQ 480
KEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERVGSSSSESCAQ
Sbjct: 421 KEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERVGSSSSESCAQ 480
Query: 481 DLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQISGLSQSEVKTD 540
DLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQISGLSQSEVKTD
Sbjct: 481 DLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQISGLSQSEVKTD 540
Query: 541 VCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLVEITEHKDFTL 600
VCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLVEITEHKDFTL
Sbjct: 541 VCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLVEITEHKDFTL 600
Query: 601 KTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCDTFGNEDFNNI 660
KTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCDTFGNEDFNNI
Sbjct: 601 KTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCDTFGNEDFNNI 660
Query: 661 QDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIPME 720
QDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIPME
Sbjct: 661 QDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIPME 720
Query: 721 CDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDT 780
CDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDT
Sbjct: 721 CDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDT 780
Query: 781 IDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESA 840
IDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESA
Sbjct: 781 IDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESA 840
Query: 841 RGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKD 900
RGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKD
Sbjct: 841 RGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKD 900
Query: 901 SSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRD 960
SSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRD
Sbjct: 901 SSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRD 960
Query: 961 SYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDC 1020
SYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDC
Sbjct: 961 SYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDC 1020
Query: 1021 PNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGR 1080
PNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGR
Sbjct: 1021 PNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGR 1080
Query: 1081 GTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFDTPADRS 1140
GTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFDTPADRS
Sbjct: 1081 GTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFDTPADRS 1140
Query: 1141 GWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSLKDQTNQQVDG 1200
GWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSLKDQTNQQVDG
Sbjct: 1141 GWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSLKDQTNQQVDG 1200
Query: 1201 SQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIHPQLPLHLHTG 1260
SQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIHPQLPLHLHTG
Sbjct: 1201 SQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIHPQLPLHLHTG 1260
Query: 1261 VPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHVSNNMSTPVLP 1320
VPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHVSNNMSTPVLP
Sbjct: 1261 VPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHVSNNMSTPVLP 1320
Query: 1321 APTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADSSKTDKKLQIQ 1380
APTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADSSKTDKKLQIQ
Sbjct: 1321 APTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADSSKTDKKLQIQ 1380
Query: 1381 EKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVANLVKAYVDKY 1440
EKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVANLVKAYVDKY
Sbjct: 1381 EKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVANLVKAYVDKY 1440
Query: 1441 KYSRKGSQKKTLEEPVSTEKNIG 1463
KYSRKGSQKKTLEEPVSTEKNIG
Sbjct: 1441 KYSRKGSQKKTLEEPVSTEKNIG 1463
>gi|221139764 PHD and ring finger domains 1 [Homo sapiens]
Length = 1648
Score = 128 bits (321), Expect = 5e-29
Identities = 85/222 (38%), Positives = 111/222 (50%), Gaps = 17/222 (7%)
Query: 1251 PQLPLHL----HTGVPLMQVATPTSVSQG----------LPPPPPPPPPSQQVNYIASQP 1296
P+ PLH G M+ PT V Q LP P P QV P
Sbjct: 1420 PRAPLHRPQKPREGAWDMEDVAPTGVRQVFSELPFPSHVLPEPGFPDTDPSQVYSPGLPP 1479
Query: 1297 DGKQLQGIPSSSHVSNNMSTPVLPAPTAAPG-NTGMVQGPSSGNTSSSSHSKASNAAVKL 1355
Q IP + VS +L G P + +S + A
Sbjct: 1480 APAQPSSIPPCALVSQPTVQFILQGSLPLVGCGAAQTLAPVPAALTPASEPASQATAASN 1539
Query: 1356 AESKVSVAVEASADSSKTD--KKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAV 1413
+E K A+ + K + KKL +QE+A +EVKLAIKPFYQ +++TKEEYK+I+RKAV
Sbjct: 1540 SEEKTPAPRLAAEKTKKEEYMKKLHMQERAVEEVKLAIKPFYQKREVTKEEYKDILRKAV 1599
Query: 1414 DKVCHSKSGEVNSTKVANLVKAYVDKYKYSRKGSQKKTLEEP 1455
K+CHSKSGE+N KVANLVKAYVDKY++ R+ + + EEP
Sbjct: 1600 QKICHSKSGEINPVKVANLVKAYVDKYRHMRRHKKPEAGEEP 1641
Score = 68.2 bits (165), Expect = 6e-11
Identities = 26/82 (31%), Positives = 50/82 (60%)
Query: 37 EADRCPICLNCLLEKEVGFPESCNHVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEG 96
+A+ CPICLN ++ VG PE+C H FC+ CI++W++ SCP+DR F+ + + G
Sbjct: 104 DAESCPICLNAFRDQAVGTPENCAHYFCLDCIVEWSKNANSCPVDRTLFKCICIRAQFGG 163
Query: 97 YVKVQVKKQLRETKDKKNENSF 118
+ ++ + + +++ + +F
Sbjct: 164 KILRKIPVENTKASEEEEDPTF 185
Score = 62.4 bits (150), Expect = 3e-09
Identities = 97/425 (22%), Positives = 159/425 (37%), Gaps = 47/425 (11%)
Query: 549 DFPTCLTSESKVYQPVSC----PLSDLSENVE--SVVNEEKITESSLVEITEHKDFTLKT 602
+ P + S++ P C P+ D + E S + K T+ E+ + D T
Sbjct: 779 NIPGNMAHSSQLSSPGFCNTFRPVDDKEQRKENPSPLFSIKKTKQLRSEVYDPSDPTGSD 838
Query: 603 EELIESPKLESSEG----EIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCDTFGNEDFN 658
S S G EI +T+ S K+ VQ + V + VE I FG E
Sbjct: 839 SSAPGSSPERSGPGLLPSEITRTISINSPKAQTVQAVRCVTSYTVESI-----FGTEPEP 893
Query: 659 NIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIP 718
+ S +KL ++ + S TE TE + E +E
Sbjct: 894 PLGPSS--------AMSKLRGAVAAEGASDTEREEPTESQGLAARLRRPSPPEPWDEEDG 945
Query: 719 MECDSFCSDQNES-------EVEPSVNADLKQMNENSVTHC---SENNMPSSDLADEKVE 768
C +F + + E E + D+ Q + V S + SS + +K +
Sbjct: 946 ASCSTFFGSEERTVTCVTVVEPEAPPSPDVLQAATHRVVELRPPSRSRSTSSSRSRKKAK 1005
Query: 769 TVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESR 828
E + + R R SR SPS + + K +S S R + + ++
Sbjct: 1006 RKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRSSSRERAK 1065
Query: 829 KSQSPSPKNESARG-----RKKSRSQSPKKDIA-----RERRQSQSRSPKRDTTRESRRS 878
+ ++ E RG R+ SRS+S + R++ + RS R RE +
Sbjct: 1066 RKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPT 1125
Query: 879 ESLSP--RRETSRENKRSQPRVKDSS--PGEKSRSQSRERESDRDGQRRERERRTRKWSR 934
SL R + RE +P K+S P ++ + +SR S+ + R R KW +
Sbjct: 1126 SSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPSSEHRAREHRRPRSREKWPQ 1185
Query: 935 SRSHS 939
+RSHS
Sbjct: 1186 TRSHS 1190
Score = 58.9 bits (141), Expect = 3e-08
Identities = 55/231 (23%), Positives = 96/231 (41%), Gaps = 22/231 (9%)
Query: 833 PSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENK 892
PSP A + + P + + +S+ ++ ++ +RE R+ S + R ++
Sbjct: 971 PSPDVLQAATHRVVELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSR 1030
Query: 893 RSQPRVKDSSPG-EKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSP---SRCRTK 948
+ P V + P ++S+++SR SDR R ER +R + +SR H R P SR ++
Sbjct: 1031 SASPSVGEERPRRQRSKAKSRRSSSDRSSSR-ERAKRKKAKDKSREHRRGPWGHSRRTSR 1089
Query: 949 SKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDAD 1008
S+S S G + Y R K + R R R+ P E + K+ +
Sbjct: 1090 SRSGSPGSSSYEHYESRKKKK------RRSASRPRGRECSPTSSLERLCRHKHQRERSHE 1143
Query: 1009 DPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSW 1059
P+ R + W ++ R+R+P E E+R S W
Sbjct: 1144 RPD-----RKESVAWPRDRRKR----RSRSPS--SEHRAREHRRPRSREKW 1183
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 124 bits (311), Expect = 7e-28
Identities = 72/151 (47%), Positives = 93/151 (61%), Gaps = 12/151 (7%)
Query: 1308 SHVSNNMSTPVLPAPTAAPGNTGMVQGPSS---------GNTSSSSHSKASNAAVKLAES 1358
SH S + PAP P + G+ GPSS G S+ + AA +
Sbjct: 1136 SHRKPPSSLGMTPAPV--PTSLGLPPGPSSYLLPGSLPLGGCGSTPPTPTGLAATS-DKR 1192
Query: 1359 KVSVAVEASADSSKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCH 1418
+ S + E D+ K KKL QE+A +EVKLAIKP+YQ KDITKEEYK+I+RKAV K+CH
Sbjct: 1193 EGSSSSEGRGDTDKYLKKLHTQERAVEEVKLAIKPYYQKKDITKEEYKDILRKAVHKICH 1252
Query: 1419 SKSGEVNSTKVANLVKAYVDKYKYSRKGSQK 1449
SKSGE+N KV+NLV+AYV +Y+Y RK +K
Sbjct: 1253 SKSGEINPVKVSNLVRAYVQRYRYFRKHGRK 1283
Score = 60.1 bits (144), Expect = 2e-08
Identities = 60/193 (31%), Positives = 87/193 (45%), Gaps = 21/193 (10%)
Query: 788 RTRRSRFHSPSTTWSPNKDT---PQEKKRPQSPSPRRETGKESRKSQS------PSPKNE 838
R R R SPS +P P +K+ + R KE+ S S P+P +
Sbjct: 490 RRERYRQRSPSPAPAPAPAAAAGPPTRKKSRRERKRSGEAKEAASSSSGTQPAPPAPASP 549
Query: 839 SARGRKKSRSQSPKKDIARE-RRQSQSRSPKRDTTRESRRSESL--SPRRETSRENKRSQ 895
+ +SR + P + RR+S+SRS R T R SR ++ RR SRE +R +
Sbjct: 550 WDSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRRR 609
Query: 896 PRVKDSSPGEKSRSQS---RERESDRDG---QRRERERRTRKWSRSRSHS-RSPSRCRTK 948
R P S S S R R RDG +++++ R+R RS S ++P+
Sbjct: 610 RRSASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPP 669
Query: 949 SKSSSFGRIDRDS 961
S S+S G DRDS
Sbjct: 670 SGSTSCG--DRDS 680
Score = 46.6 bits (109), Expect = 2e-04
Identities = 96/436 (22%), Positives = 152/436 (34%), Gaps = 94/436 (21%)
Query: 757 MPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQS 816
+P D E+ E V QP E P+ + + P R +R P+ S TP + PQ
Sbjct: 384 LPPGDSEIEEGEIV-QPEEEPRLALSLFR-PGGRAAR---PTPAASA---TPTAQPLPQP 435
Query: 817 PSP---------------------------------------------------RRETGK 825
P+P RRE +
Sbjct: 436 PAPRAPEGDDFLSLHAESDGEGALQVDLGEPAPAPPAADSRWGGLDLRRKILTQRRERYR 495
Query: 826 ESRKSQSPSPKNESARG---RKKSRSQSPKKDIARERRQSQS------RSPKRDTTRESR 876
+ S +P+P +A G RKKSR + + A+E S S +P +
Sbjct: 496 QRSPSPAPAPAPAAAAGPPTRKKSRRERKRSGEAKEAASSSSGTQPAPPAPASPWDSKKH 555
Query: 877 RSESLSP-RRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSR- 934
RS P +S +RS+ R + S +SRS R R R + RE+ RR R+ +
Sbjct: 556 RSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRSASP 615
Query: 935 --SRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQ 992
+ S S S R R + K G + R +G R G+++ P
Sbjct: 616 PPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGE-----KRSGDGSEKAPAPAPPPS 670
Query: 993 NENTRKEKNDIHLDADDPNSADKHRND---CPNWITEKINSGPDPRTRNPEKLKESHWE- 1048
+ +++ A P+ D +D IT DPR +P E
Sbjct: 671 GSTSCGDRDSRRRGAVPPSIQDLTDHDLFAIKRTITVGRLDKSDPRGPSPAPASSPKREV 730
Query: 1049 ---------ENRNENSGNSWNKNFGSGWVSNRGRGRGNRGR---GTYRSSFAYKDQNENR 1096
E R S + G+ S+ R +G+R + G R +D++ +R
Sbjct: 731 LYDSEGLSGEERGGKSSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDRDRDRDR 790
Query: 1097 WQNR-KPLSGNSNSSG 1111
+ +P ++ SSG
Sbjct: 791 SSKKARPPKESAPSSG 806
Score = 34.7 bits (78), Expect = 0.69
Identities = 46/219 (21%), Positives = 79/219 (36%), Gaps = 48/219 (21%)
Query: 783 KTKKPRTRRSRFHSPSTTWSPNK-------------DTPQEKKRPQSPSPRRE-TGKESR 828
+ K+ R RRS P+T+ S + + ++KKR +S +R G E
Sbjct: 603 REKRRRRRRSASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKA 662
Query: 829 KSQSPSPKNESARGRKKSRSQSP-------------------------KKDIARERRQSQ 863
+ +P P ++ G + SR + K R +
Sbjct: 663 PAPAPPPSGSTSCGDRDSRRRGAVPPSIQDLTDHDLFAIKRTITVGRLDKSDPRGPSPAP 722
Query: 864 SRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQ---------SRER 914
+ SPKR+ +S ++S++++R SS + S+ R+R
Sbjct: 723 ASSPKREVLYDSEGLSGEERGGKSSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDR 782
Query: 915 ESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSS 953
+ DRD R ++ R K S S + S SSS
Sbjct: 783 DRDRDRDRSSKKARPPKESAPSSGPPPKPPVSSGSGSSS 821
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 88.6 bits (218), Expect = 4e-17
Identities = 90/419 (21%), Positives = 168/419 (40%), Gaps = 30/419 (7%)
Query: 736 SVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFH 795
S N++ E ++ + P D D+ ++ + +D D ++ + S
Sbjct: 587 SSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIR 646
Query: 796 SPSTTWSPNKDTPQEKKRPQSPSPRR-ETGKESRKSQSPSPKNESARGRKKSRSQSPKKD 854
+D +E++R RR E +E + + + E R R++ R + +++
Sbjct: 647 HQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERE 706
Query: 855 IARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQ---- 910
+ RER + + R +++ RE R RE RE R + R ++ E+ R +
Sbjct: 707 LERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERER 766
Query: 911 --SRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPR-WK 967
RERE +R +R + R R W + R K + R RD + R K
Sbjct: 767 ERERERERERARERDKERERQRDW---EDKDKGRDDRREKREEIREDRNPRDGHDERKSK 823
Query: 968 GRWANDGWRCPRGN-DRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDCPNWITE 1026
R+ N+G PR + R R++ P+ N+ +KN+ H + R+ P+ +TE
Sbjct: 824 KRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTE 883
Query: 1027 KINSGPDPRTRNPEKLKES-HWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGRGTYRS 1085
R PE+ + S +EE + +S +K + R R G ++S
Sbjct: 884 DRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQS 943
Query: 1086 -----SFAYKDQNENRWQ-NRKPLS-----------GNSNSSGSESFKFVEQQSYKRKS 1127
S D+N+ + + +KP+ GN ++ + F ++ K+KS
Sbjct: 944 EDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKS 1002
Score = 84.0 bits (206), Expect = 1e-15
Identities = 142/592 (23%), Positives = 240/592 (40%), Gaps = 100/592 (16%)
Query: 602 TEELIESPKLESSEGEIIQTVDRQSVK--SPEVQLLGHVETEDVEIIATCDTFGNEDFNN 659
TEE + ESS G + D + K +PE E E+VE D N D N
Sbjct: 105 TEESSSPVRKESSRGRHREKEDIKITKERTPES------EEENVEWETNRDDSDNGDINY 158
Query: 660 IQDSENNL-LKNNLLNTKLEK----SLEEKNESLTEHPRSTELPKTHIE---QIQKHFSE 711
E +L +K + +L K ++E++ E + + S E+ ++ + ++K
Sbjct: 159 DYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKS 218
Query: 712 DNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSS---------DL 762
+ P + D+ S +V++ L NS T+ S+ P + D+
Sbjct: 219 PKRKSSPKSSSASKKDRKTS----AVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDI 274
Query: 763 A-----DEKVETVSQPSESPKDTID----------KTKKPRTRR----------SRFHSP 797
A EK + + E +D D K KPR+ SR HS
Sbjct: 275 ALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSS 334
Query: 798 STTW--SPNKDTPQ-EKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKD 854
S+ S + +P +KR SPS +R R+S SP P + + ++K QSP +
Sbjct: 335 SSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRK---QSPPR- 390
Query: 855 IARERRQSQSRSPKRDTTR--ESRRSESLSPRRETSRENKRSQPRVKDSSPG---EKSRS 909
RSP R+ R R S+S R E + + + R KDS E+ +S
Sbjct: 391 ---------HRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQS 441
Query: 910 QSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPR--WK 967
SR+ DR+ R R+RR + +R R R R + + R ++S PR
Sbjct: 442 SSRDHRDDRE-PRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRS 500
Query: 968 GRWANDGWRCPRGNDRYRKND--PEKQNENTRKEKNDIHLDADDPNSADKHRNDCPNWIT 1025
R A+D +R G D +RK D PE+ R HL + +S + RN+ N
Sbjct: 501 TRDAHD-YRDREGRDTHRKEDTYPEESRSYGRN-----HL--REESSRTEIRNESRNESR 552
Query: 1026 EKINSGPDPRTRN--PEKLKESHWEENRNENSGNSWNKNFGSGWVS-------NRGRGRG 1076
+I + R+R PE ++ ++ +S N N+ W + +R R
Sbjct: 553 SEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERD 612
Query: 1077 NRGR---GTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKR 1125
NR + ++ +D+ +NR ++++P S + ++ + E++ +R
Sbjct: 613 NRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERR 664
Score = 52.8 bits (125), Expect = 2e-06
Identities = 71/286 (24%), Positives = 117/286 (40%), Gaps = 37/286 (12%)
Query: 767 VETVSQPSESPKDTI----DKTKKPRTRRSRFHSPSTTWSPNKDT-PQEKKRPQSPSPRR 821
+ T + P+ + +T K RTR + +P T + P ++KR S R
Sbjct: 1137 ISTSATPTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNR 1196
Query: 822 ETGKESRKSQSPSPKNESARGRKKSRSQSPKKDI----ARERRQSQS------RSPKRDT 871
+ + + SP N+SA + QS +K + +R+R +++S R + D
Sbjct: 1197 -SNRSHTSGRLRSPSNDSAH--RSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQ 1253
Query: 872 TRESRRSESLSPRRETSREN--KRSQP----RVKDSSPGEKSRSQSRERESDRDGQRRER 925
+ S S S R+ SR + +RS P +V S SR + +ER+ + RER
Sbjct: 1254 LKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERER 1313
Query: 926 ER---RTRKWSR--SRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRG 980
ER R R+W R + R+ R R + + R D+ R + R +D R
Sbjct: 1314 ERRDTRQREWDRDADKDWPRNRDRDRLRERERERER-DKRRDLDRERERLISDSVERDRD 1372
Query: 981 NDRYRKNDPEKQNENTRKE-------KNDIHLDADDPNSADKHRND 1019
DR R + + R E + D+ + D + DK R D
Sbjct: 1373 RDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMD 1418
Score = 52.0 bits (123), Expect = 4e-06
Identities = 104/487 (21%), Positives = 181/487 (37%), Gaps = 73/487 (14%)
Query: 594 EHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCDTFG 653
E K+ + + EE K+ S + + QT +S + ++GH ++ED E T D
Sbjct: 897 ERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRE---TSDRAH 953
Query: 654 NEDFNNIQDSENNLLKNNLLNTKLEK-SLEEKNESLTEHPRSTELPKTHIEQIQKHFSED 712
+E+ + + + K + +E+ ++E +E K IE+ +K D
Sbjct: 954 DENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGD 1013
Query: 713 NNEMIPMECDSFCSDQNESEVEP-----SVNADLKQM--NENSVTHCSENNMPS--SDLA 763
++ D + Q++ + P + +L +M +N + S+ + SD +
Sbjct: 1014 SD-----ISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWS 1068
Query: 764 DEKV------------ETVSQPSESPKD------------TIDKTKKPRTRRSRFHSPST 799
DE V T + P +P T T P T + + +T
Sbjct: 1069 DEDVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAAT 1128
Query: 800 TWSPNKDTPQEKKRPQSPSPRRETGKES---------RKSQSPSPKNESARGRK----KS 846
++S + T P + + ++S K ++P E A+ RK K
Sbjct: 1129 SFSTSAITISTSATPTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKR 1188
Query: 847 RSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEK 906
S R + RSP D+ S +S R S R + + + + K
Sbjct: 1189 SSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERK 1248
Query: 907 SR-------SQSRERESDRDGQRRERERRTRKWSRSRSHSRS---PSRCRTKSK-----S 951
SR SR SDR R RR+ S + HSRS SR R + +
Sbjct: 1249 SRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHD 1308
Query: 952 SSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPN 1011
R RD+ W R A+ W PR DR R + E++ E ++ D + +
Sbjct: 1309 RERERERRDTRQREW-DRDADKDW--PRNRDRDRLRERERERERDKRRDLDRERERLISD 1365
Query: 1012 SADKHRN 1018
S ++ R+
Sbjct: 1366 SVERDRD 1372
Score = 49.3 bits (116), Expect = 3e-05
Identities = 41/163 (25%), Positives = 69/163 (42%), Gaps = 6/163 (3%)
Query: 803 PNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQS 862
P++ T +++ +S S RR + + R+ S S +S ++ ++ RERR +
Sbjct: 1259 PSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDT 1318
Query: 863 QSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQR 922
+ R RD ++ R+ RE RE +R + R D E+ S S ER+ DRD R
Sbjct: 1319 RQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRE-RERLISDSVERDRDRDRDR 1377
Query: 923 RERERRTRKWSRSRS-----HSRSPSRCRTKSKSSSFGRIDRD 960
+ R + H R S + R+D+D
Sbjct: 1378 TFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKD 1420
Score = 38.5 bits (88), Expect = 0.048
Identities = 99/471 (21%), Positives = 174/471 (36%), Gaps = 94/471 (19%)
Query: 778 KDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKK-RPQSPSPRRETGKESRKSQSPSPK 836
K T++ TK SR S P+ + E + R + G R PSP+
Sbjct: 7 KVTVENTKTISDSTSRRPSVFERLGPSTGSTAETQCRNWLKTGNCLYGNTCRFVHGPSPR 66
Query: 837 NESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSE-SLSP-RRETSRENKRS 894
+G + +SP++ R + +++ DT + R +E S SP R+E+SR R
Sbjct: 67 G---KGYSSNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHRE 123
Query: 895 QPRVK-DSSPGEKSRSQSRERESDRDG------------------QRRERERRTRKWSRS 935
+ +K +S ++ E E++RD +R++ +R K +
Sbjct: 124 KEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQE 183
Query: 936 RSHSRSPSRCR-------TKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKND 988
R + +SK S + + S SP+ RK+
Sbjct: 184 NMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPK-------------------RKSS 224
Query: 989 PEKQNENTRKEKNDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPE------KL 1042
P+ + + K D A D+ RN N +K P P PE K
Sbjct: 225 PKSSSAS----KKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKY 280
Query: 1043 KESHWEENRNE---NSGNSWNKNFGSGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQN 1099
KE + ++R E G ++F R R + ++ R T + Q+
Sbjct: 281 KEKYKVKDRIEEKTRDGKDRGRDF------ERQREKRDKPRSTSPAG-----------QH 323
Query: 1100 RKPLSGNSNSSGSESFKFVEQQ--SYKRKSEQEFSFD---TPADRSGWTSASSWAV---- 1150
P+S +SS S+S +++ S +RK S+ TP R + S ++
Sbjct: 324 HSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQ 383
Query: 1151 RKTLPADVQNYYSRRGRN----SSGPQSGWMKQEEETSGQDSSLKDQTNQQ 1197
RK P ++ +GR+ +S ++ E+T G+ KD ++
Sbjct: 384 RKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREER 434
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 88.2 bits (217), Expect = 5e-17
Identities = 102/418 (24%), Positives = 168/418 (40%), Gaps = 45/418 (10%)
Query: 731 SEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTR 790
S E + D ++NE EN + + K+ SESP +K KK +
Sbjct: 375 SSGERWIKGDKSELNE-----IKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDH 429
Query: 791 RSRFHSPSTTWSPNKDTPQEKK-RPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQ 849
+S + KD + K + ++ S R KE KS+ K+ + K+ RS+
Sbjct: 430 KSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKH-NRNEEKRMRSR 488
Query: 850 SPKKD---IARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEK 906
S +D + + +QS S+ ++ +R +S+ L + S E+ S+ + KD
Sbjct: 489 SKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESK---SNEHDHSKSKEKD------ 539
Query: 907 SRSQSRERESDRDGQRRERERRTRKWSRSRSHS---RSPSRCRTKSKSSSFGRIDRDSYS 963
R+QSR RE D + RTR+ SRSR S RS + R +S+S + R Y
Sbjct: 540 RRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEY- 598
Query: 964 PRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDCPNW 1023
R +GR + R P G R K R++ + + DK+RN
Sbjct: 599 -RRRGRSRSRERRTPPGRSR------SKDRRRRRRDSRSSEREESQSRNKDKYRNQ---- 647
Query: 1024 ITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGRGTY 1083
S R N E K + ++R+ NS N+ + S + + +
Sbjct: 648 -----ESKSSHRKENSESEKRM-YSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNEL 701
Query: 1084 RSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFDTPADRSG 1141
+SS ++E + + N S G E+ E+ +K + E S T D+SG
Sbjct: 702 KSSMLKNKEDEKIRSSVE--KENQKSKGQENDHVHEK---NKKFDHESSPGTDEDKSG 754
Score = 75.1 bits (183), Expect = 5e-13
Identities = 78/392 (19%), Positives = 151/392 (38%), Gaps = 50/392 (12%)
Query: 761 DLADEKVETVSQPSESPK-----DTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQ 815
++ ++K + S+P + + I K+K + + R S S++ S + D+
Sbjct: 153 EIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDS-------- 204
Query: 816 SPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSR-SPKRDTTRE 874
++ +S+ S S + + K R + +K+ + +++ + R K+ + E
Sbjct: 205 ------DSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSE 258
Query: 875 SR------------RSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQR 922
S R E + P E ++S P+ + K+R + RERE + +
Sbjct: 259 SEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKE--RKNRERERERECNPPNSQ 316
Query: 923 RERERRTRKWSRS--RSHSRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRG 980
+R +RS + R P R RT S+S S R R P W+
Sbjct: 317 PASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSS 376
Query: 981 NDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPE 1040
+R+ K D + NE +++ + + HRN ++ P+ + +
Sbjct: 377 GERWIKGDKSELNEIKENQRSPVRV---KERKITDHRN---------VSESPNRKNEKEK 424
Query: 1041 KLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNR 1100
K+K+ + NS + V R + + +R + +S +D NR
Sbjct: 425 KVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSK-SRSKSKEKSKSKERDSKHNR-NEE 482
Query: 1101 KPLSGNSNSSGSESFKFVEQQSYKRKSEQEFS 1132
K + S E+ K E+QS + +QE S
Sbjct: 483 KRMRSRSKGRDHENVKEKEKQSDSKGKDQERS 514
Score = 67.8 bits (164), Expect = 7e-11
Identities = 116/594 (19%), Positives = 222/594 (37%), Gaps = 100/594 (16%)
Query: 328 RAETASQSQRSPISDNSGCDAPGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLK 387
R +++S S S +S D+ +S+ S S S+ E + + R+ RK+ R+ +K K
Sbjct: 190 RHKSSSSSSSSSSDSDSSSDSQSSSDSSDS-ESATEEKSKKRKKKHRKNSRKHKKE---K 245
Query: 388 KKLRSSVAAPEKSSSNDSVDEETAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCL 447
KK + S +KS+S++S + E E+ + E P + + +
Sbjct: 246 KKRKKS----KKSASSES-EAENLEAQPQSTVRPEEIPPIPENRFL-------------M 287
Query: 448 KSCNEQIEESEKHTANYDTEERVGSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCL 507
+ + +E E+ + E +S+ + +LV G +K++ G
Sbjct: 288 RKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSG--RKIKGRGPRRYRTPS 345
Query: 508 ESEISENILEKGGDPLEKQDQISGLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCP 567
S S + + P + ++ + V +S + +
Sbjct: 346 RSR-SRDRFRRSETPPHWRQEMQRAQRMRV-----------------SSGERWIKGDKSE 387
Query: 568 LSDLSENVESVVN--EEKITESSLVEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQ 625
L+++ EN S V E KIT+ ++E + + E+ ++ K S E +I + ++
Sbjct: 388 LNEIKENQRSPVRVKERKITDHR--NVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKD 445
Query: 626 SVKSPEVQLLGHVETEDVEIIATCDTFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKN 685
D N +K + KS +EK+
Sbjct: 446 ------------------------------------DKYKNKVKKRAKSKSRSKS-KEKS 468
Query: 686 ESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMN 745
+S + + + K +N + + DS DQ S + + N
Sbjct: 469 KSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSN 528
Query: 746 ENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNK 805
E+ + E + + + E T + S + + + R+RR R S T ++
Sbjct: 529 EHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVR----SRTHDRDR 584
Query: 806 DTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSR 865
+E R + RR SR+ ++P R R K R + + + ER +SQSR
Sbjct: 585 SRSKEYHRYREQEYRRRGRSRSRERRTP-----PGRSRSKDRRRRRRDSRSSEREESQSR 639
Query: 866 SPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRD 919
+ + +ES+ S +EN S+ R+ S S + SRE+++DRD
Sbjct: 640 NKDKYRNQESKSSH--------RKENSESEKRMYSKSRDHNSSNNSREKKADRD 685
Score = 67.0 bits (162), Expect = 1e-10
Identities = 113/582 (19%), Positives = 221/582 (37%), Gaps = 87/582 (14%)
Query: 697 LPKTHI--EQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSE 754
+PK+ + E+ ++H S ++ + DS Q+ S+ S +A ++ + H
Sbjct: 178 IPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKN 237
Query: 755 NNMPSSDLADEKVETVSQPSES--------PKDTIDKTKKPRTRRSRF----HSPSTTWS 802
+ + K S SES P+ T+ + P +RF P
Sbjct: 238 SRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEK 297
Query: 803 PNKDTPQEKKRPQSP----------------SPRRETGKESRKSQSPSPKNESARGRKKS 846
K+ +E++R +P S R+ G+ R+ ++PS R R+
Sbjct: 298 ERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSE 357
Query: 847 RSQSPKKDIARERRQSQS--------------------RSPKRDTTRE--SRRSESLSPR 884
++++ R +R S RSP R R+ R+ S SP
Sbjct: 358 TPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPN 417
Query: 885 RETSRENK----RSQPRVKDSSPGE--------------KSRSQSRERESDRDGQRRERE 926
R+ +E K +S + +D KS+S+S+ +E + +R +
Sbjct: 418 RKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKH 477
Query: 927 RRT-RKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYR 985
R K RSRS R + K K S D++ + K + + N+
Sbjct: 478 NRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLES-----KSNEHDH 532
Query: 986 KNDPEK-QNENTRKEKNDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKE 1044
EK + +R + DI NS + R+ + + ++ S R R+ + KE
Sbjct: 533 SKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRD-RSRRVRSRTHDRDRS--RSKE 589
Query: 1045 SH-WEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPL 1103
H + E G S ++ + +R + R R R + RSS + Q+ N+ + R
Sbjct: 590 YHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDS-RSSEREESQSRNKDKYRNQE 648
Query: 1104 SGNSN-SSGSESFKFVEQQSYKRKSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQNYY 1162
S +S+ SES E++ Y + + S ++ ++ + ++++ +
Sbjct: 649 SKSSHRKENSES----EKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSS 704
Query: 1163 SRRGRNSSGPQSGWMKQEEETSGQDSSLKDQTNQQVDGSQLP 1204
+ + +S K+ +++ GQ++ + N++ D P
Sbjct: 705 MLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHESSP 746
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo
sapiens]
Length = 624
Score = 87.4 bits (215), Expect = 9e-17
Identities = 76/319 (23%), Positives = 148/319 (46%), Gaps = 23/319 (7%)
Query: 758 PSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSP 817
P S ++E+ S+ K R +RS+ S + + ++ ++++R +SP
Sbjct: 295 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSP 354
Query: 818 SPRRETGKESRKSQSPS---PKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRE 874
+R +E RKS+S S K + R + K + + +KD +ER + + R +++ +
Sbjct: 355 HKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN 414
Query: 875 SRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQR-----RERERRT 929
R + RE +E R + R K+ EK R + +E+E D++ +R +E + +
Sbjct: 415 KDRDKEREKDREKDKEKDREREREKEH---EKDRDKEKEKEQDKEKEREKDRSKEIDEKR 471
Query: 930 RKWSRSRSHSRSPSRCRTKSKSSSFGRIDR----DSYSPRWKGRWANDGWRCP---RGND 982
+K +SR+ RS + R +S+SSS R R S SPR R P N
Sbjct: 472 KKDKKSRTPPRSYNASR-RSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 530
Query: 983 RYRKNDPEKQNENTRKEK---NDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNP 1039
+ +K + E+ + + R+E+ + ++D + +K + + ++ N PD
Sbjct: 531 KDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 590
Query: 1040 EKLKES-HWEENRNENSGN 1057
K++ EEN+ +++GN
Sbjct: 591 VDDKDAPRTEENKIQHNGN 609
Score = 80.5 bits (197), Expect = 1e-14
Identities = 80/306 (26%), Positives = 126/306 (41%), Gaps = 32/306 (10%)
Query: 773 PSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQS 832
P + K+ + K+ R +S S P E+K +S S R + S KS S
Sbjct: 268 PQAAAKELEEVMKRVREAQSFI---SAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHS 324
Query: 833 PSPKNESA-RGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLS---PRRETS 888
+++S R R +RS+S +KD RR+S+S KR +RE R+S S S +R+ +
Sbjct: 325 RRKRSQSKHRSRSHNRSRSRQKD----RRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDT 380
Query: 889 RENKRSQPRVKDSSPGEKSRSQSRERE--------SDRDGQRRERERRTRKWSRSRSHSR 940
RE + + RVK+ EK R + +ERE DRD +R + + ++ R R +
Sbjct: 381 REKIKEKERVKEKD-REKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREK 439
Query: 941 SPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEK 1000
+ R K K ++D R K R + R D+ + P N + R
Sbjct: 440 EHEKDRDKEKEK-----EQDKEKEREKDRSKEIDEK--RKKDKKSRTPPRSYNASRRSRS 492
Query: 1001 NDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLK----ESHWEENRNENSG 1056
+ S+ + I K + P PR+RN + K H E R
Sbjct: 493 SSRERRRRRSRSSSRSPRTSKT-IKRKSSRSPSPRSRNKKDKKREKERDHISERRERERS 551
Query: 1057 NSWNKN 1062
S K+
Sbjct: 552 TSMRKS 557
Score = 52.0 bits (123), Expect = 4e-06
Identities = 41/198 (20%), Positives = 85/198 (42%), Gaps = 14/198 (7%)
Query: 730 ESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRT 789
E E + + + + E H + + D++ E S+ + K KK RT
Sbjct: 420 EREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRT 479
Query: 790 RRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQ 849
+++ + S +++ + + R S SPR + + S+SPSP++ + KK + +
Sbjct: 480 PPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRN----KKDKKR 535
Query: 850 SPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRS 909
++D ERR+ + + R ++ + E L + +E + ++ E S
Sbjct: 536 EKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNK---------EPDSS 586
Query: 910 QSRERESDRDGQRRERER 927
S+E + D+D R E +
Sbjct: 587 VSKEVD-DKDAPRTEENK 603
Score = 42.7 bits (99), Expect = 0.003
Identities = 49/240 (20%), Positives = 95/240 (39%), Gaps = 15/240 (6%)
Query: 679 KSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVN 738
K E E E R E + ++ K+ D E D + E E E +
Sbjct: 385 KEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKD 444
Query: 739 ADLKQMNENSVTHCSENN----MPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRF 794
D ++ E E + + D+K T + + + + +++ R RRSR
Sbjct: 445 RDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSR- 503
Query: 795 HSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKD 854
S++ SP ++K +SPSPR K+ ++ + ++ + R++ RS S +K
Sbjct: 504 ---SSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKE---RDHISERRERERSTSMRK- 556
Query: 855 IARERRQSQSRSPKRDTTRESRRSESLSPRRETSRE-NKRSQPRVKDSSPGEKSRSQSRE 913
+ R + + K T+ + + + P S+E + + PR +++ Q E
Sbjct: 557 -SSNDRDGKEKLEKNSTSLK-EKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNE 614
Score = 41.6 bits (96), Expect = 0.006
Identities = 43/186 (23%), Positives = 80/186 (43%), Gaps = 18/186 (9%)
Query: 293 QEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNS 352
+E E +K S + + + K + T P RS +R +S +R S +P S
Sbjct: 455 KEKEREKDRSKEIDEKRKKDKKSRTPP--RSYNASRRSRSSSRERRRRRSRSSSRSPRTS 512
Query: 353 NPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAE 412
S + S + + K++ R +++ +S+ + SSND +E E
Sbjct: 513 KTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSM----RKSSNDRDGKEKLE 568
Query: 413 SDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESE-KHTANYDTEERVG 471
+++ + EKEH + DSS V V+++ A + EE++ +H N E
Sbjct: 569 KNSTSLKEKEHNKEPDSS----VSKEVDDKDA-------PRTEENKIQHNGNCQLNEENL 617
Query: 472 SSSSES 477
S+ +E+
Sbjct: 618 STKTEA 623
Score = 35.0 bits (79), Expect = 0.53
Identities = 46/205 (22%), Positives = 71/205 (34%), Gaps = 29/205 (14%)
Query: 294 EGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNS- 352
+ E+K S+TR R + + R+ +++ + RS D +P
Sbjct: 299 KSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKR 358
Query: 353 ------NPSLSVPSSAESEKQTRQAPKRK--------SVRRGRKPPLLKKKLRSSVAAPE 398
S S S + K TR+ K K R R+ K+K R +
Sbjct: 359 SKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRD 418
Query: 399 KSSSNDSVDEETAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESE 458
K D E+ E D EKEH+ D D E + K +++I+E
Sbjct: 419 KEREKDR--EKDKEKDREREREKEHEKDRDKEKEKEQDKEKERE-----KDRSKEIDEKR 471
Query: 459 KH-------TANYDTEERVGSSSSE 476
K +Y+ R SSS E
Sbjct: 472 KKDKKSRTPPRSYNASRRSRSSSRE 496
Score = 32.7 bits (73), Expect = 2.6
Identities = 38/176 (21%), Positives = 63/176 (35%), Gaps = 7/176 (3%)
Query: 302 SGTSNTR-GSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNSNPSLSVPS 360
SG SN R G R + + +R S+++ SQS+ S N + S S P
Sbjct: 297 SGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKS-PH 355
Query: 361 SAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAESDTSPVLE 420
S+ + R+ + +S R + +K R + E+ D E E + E
Sbjct: 356 KKRSKSRERRKSRSRSHSRDK-----RKDTREKIKEKERVKEKDREKEREREKEREKEKE 410
Query: 421 KEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERVGSSSSE 476
+ D D + E + +E+ + EK +ER S E
Sbjct: 411 RGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKE 466
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo
sapiens]
Length = 508
Score = 87.4 bits (215), Expect = 9e-17
Identities = 76/319 (23%), Positives = 148/319 (46%), Gaps = 23/319 (7%)
Query: 758 PSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSP 817
P S ++E+ S+ K R +RS+ S + + ++ ++++R +SP
Sbjct: 179 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSP 238
Query: 818 SPRRETGKESRKSQSPS---PKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRE 874
+R +E RKS+S S K + R + K + + +KD +ER + + R +++ +
Sbjct: 239 HKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN 298
Query: 875 SRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQR-----RERERRT 929
R + RE +E R + R K+ EK R + +E+E D++ +R +E + +
Sbjct: 299 KDRDKEREKDREKDKEKDREREREKEH---EKDRDKEKEKEQDKEKEREKDRSKEIDEKR 355
Query: 930 RKWSRSRSHSRSPSRCRTKSKSSSFGRIDR----DSYSPRWKGRWANDGWRCP---RGND 982
+K +SR+ RS + R +S+SSS R R S SPR R P N
Sbjct: 356 KKDKKSRTPPRSYNASR-RSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 414
Query: 983 RYRKNDPEKQNENTRKEK---NDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNP 1039
+ +K + E+ + + R+E+ + ++D + +K + + ++ N PD
Sbjct: 415 KDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 474
Query: 1040 EKLKES-HWEENRNENSGN 1057
K++ EEN+ +++GN
Sbjct: 475 VDDKDAPRTEENKIQHNGN 493
Score = 80.5 bits (197), Expect = 1e-14
Identities = 80/306 (26%), Positives = 126/306 (41%), Gaps = 32/306 (10%)
Query: 773 PSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQS 832
P + K+ + K+ R +S S P E+K +S S R + S KS S
Sbjct: 152 PQAAAKELEEVMKRVREAQSFI---SAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHS 208
Query: 833 PSPKNESA-RGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLS---PRRETS 888
+++S R R +RS+S +KD RR+S+S KR +RE R+S S S +R+ +
Sbjct: 209 RRKRSQSKHRSRSHNRSRSRQKD----RRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDT 264
Query: 889 RENKRSQPRVKDSSPGEKSRSQSRERE--------SDRDGQRRERERRTRKWSRSRSHSR 940
RE + + RVK+ EK R + +ERE DRD +R + + ++ R R +
Sbjct: 265 REKIKEKERVKEKD-REKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREK 323
Query: 941 SPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEK 1000
+ R K K ++D R K R + R D+ + P N + R
Sbjct: 324 EHEKDRDKEKEK-----EQDKEKEREKDRSKEIDEK--RKKDKKSRTPPRSYNASRRSRS 376
Query: 1001 NDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLK----ESHWEENRNENSG 1056
+ S+ + I K + P PR+RN + K H E R
Sbjct: 377 SSRERRRRRSRSSSRSPRTSKT-IKRKSSRSPSPRSRNKKDKKREKERDHISERRERERS 435
Query: 1057 NSWNKN 1062
S K+
Sbjct: 436 TSMRKS 441
Score = 52.0 bits (123), Expect = 4e-06
Identities = 41/198 (20%), Positives = 85/198 (42%), Gaps = 14/198 (7%)
Query: 730 ESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRT 789
E E + + + + E H + + D++ E S+ + K KK RT
Sbjct: 304 EREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRT 363
Query: 790 RRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQ 849
+++ + S +++ + + R S SPR + + S+SPSP++ + KK + +
Sbjct: 364 PPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRN----KKDKKR 419
Query: 850 SPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRS 909
++D ERR+ + + R ++ + E L + +E + ++ E S
Sbjct: 420 EKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNK---------EPDSS 470
Query: 910 QSRERESDRDGQRRERER 927
S+E + D+D R E +
Sbjct: 471 VSKEVD-DKDAPRTEENK 487
Score = 42.7 bits (99), Expect = 0.003
Identities = 49/240 (20%), Positives = 95/240 (39%), Gaps = 15/240 (6%)
Query: 679 KSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVN 738
K E E E R E + ++ K+ D E D + E E E +
Sbjct: 269 KEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKD 328
Query: 739 ADLKQMNENSVTHCSENN----MPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRF 794
D ++ E E + + D+K T + + + + +++ R RRSR
Sbjct: 329 RDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSR- 387
Query: 795 HSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKD 854
S++ SP ++K +SPSPR K+ ++ + ++ + R++ RS S +K
Sbjct: 388 ---SSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKE---RDHISERRERERSTSMRK- 440
Query: 855 IARERRQSQSRSPKRDTTRESRRSESLSPRRETSRE-NKRSQPRVKDSSPGEKSRSQSRE 913
+ R + + K T+ + + + P S+E + + PR +++ Q E
Sbjct: 441 -SSNDRDGKEKLEKNSTSLK-EKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNE 498
Score = 41.6 bits (96), Expect = 0.006
Identities = 43/186 (23%), Positives = 80/186 (43%), Gaps = 18/186 (9%)
Query: 293 QEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNS 352
+E E +K S + + + K + T P RS +R +S +R S +P S
Sbjct: 339 KEKEREKDRSKEIDEKRKKDKKSRTPP--RSYNASRRSRSSSRERRRRRSRSSSRSPRTS 396
Query: 353 NPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAE 412
S + S + + K++ R +++ +S+ + SSND +E E
Sbjct: 397 KTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSM----RKSSNDRDGKEKLE 452
Query: 413 SDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESE-KHTANYDTEERVG 471
+++ + EKEH + DSS V V+++ A + EE++ +H N E
Sbjct: 453 KNSTSLKEKEHNKEPDSS----VSKEVDDKDA-------PRTEENKIQHNGNCQLNEENL 501
Query: 472 SSSSES 477
S+ +E+
Sbjct: 502 STKTEA 507
Score = 35.0 bits (79), Expect = 0.53
Identities = 46/205 (22%), Positives = 71/205 (34%), Gaps = 29/205 (14%)
Query: 294 EGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNS- 352
+ E+K S+TR R + + R+ +++ + RS D +P
Sbjct: 183 KSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKR 242
Query: 353 ------NPSLSVPSSAESEKQTRQAPKRK--------SVRRGRKPPLLKKKLRSSVAAPE 398
S S S + K TR+ K K R R+ K+K R +
Sbjct: 243 SKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRD 302
Query: 399 KSSSNDSVDEETAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESE 458
K D E+ E D EKEH+ D D E + K +++I+E
Sbjct: 303 KEREKDR--EKDKEKDREREREKEHEKDRDKEKEKEQDKEKERE-----KDRSKEIDEKR 355
Query: 459 KH-------TANYDTEERVGSSSSE 476
K +Y+ R SSS E
Sbjct: 356 KKDKKSRTPPRSYNASRRSRSSSRE 380
Score = 32.7 bits (73), Expect = 2.6
Identities = 38/176 (21%), Positives = 63/176 (35%), Gaps = 7/176 (3%)
Query: 302 SGTSNTR-GSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNSNPSLSVPS 360
SG SN R G R + + +R S+++ SQS+ S N + S S P
Sbjct: 181 SGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKS-PH 239
Query: 361 SAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAESDTSPVLE 420
S+ + R+ + +S R + +K R + E+ D E E + E
Sbjct: 240 KKRSKSRERRKSRSRSHSRDK-----RKDTREKIKEKERVKEKDREKEREREKEREKEKE 294
Query: 421 KEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERVGSSSSE 476
+ D D + E + +E+ + EK +ER S E
Sbjct: 295 RGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKE 350
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 86.3 bits (212), Expect = 2e-16
Identities = 75/273 (27%), Positives = 116/273 (42%), Gaps = 21/273 (7%)
Query: 753 SENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEK- 811
S + S + K + SQ K ++ RSR HS + S +KD +EK
Sbjct: 218 SRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKI 277
Query: 812 ------KRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSR 865
+P+S SP R K +S+S + E + SR +S +K + + R +S+S+
Sbjct: 278 QNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSK 337
Query: 866 SPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRER 925
R +R +S+ R+ SRE RS+ R + S E+SR + +R+S ++++
Sbjct: 338 GGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKS--ERSRKRGSKRDSKAGSSKKKK 395
Query: 926 ERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYR 985
+ T + S+SRS SRS S+ R +KS S R R G N G R R
Sbjct: 396 KEDTDR-SQSRSPSRSVSKEREHAKSESSQREGR--------GESENAG---TNQETRSR 443
Query: 986 KNDPEKQNENTRKEKNDIHLDADDPNSADKHRN 1018
K N E A S K R+
Sbjct: 444 SRSNSKSKPNLPSESRSRSKSASKTRSRSKSRS 476
Score = 79.7 bits (195), Expect = 2e-14
Identities = 82/332 (24%), Positives = 137/332 (41%), Gaps = 35/332 (10%)
Query: 786 KPRTRRSRFHSPSTTWSPNKDTPQE--KKRPQSPSPRRETGKESRKSQSPSPKNESARGR 843
KP +RR R +S S + S ++ + K R +S S + K +S+S S +R R
Sbjct: 176 KPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSR 235
Query: 844 -------KKSRSQSPKKDIARERRQS--QSRSPKRDTTRESRRS-------ESLSPRRET 887
KK +S+SP K+ +R R S +SRS +D E ++ +S SP R
Sbjct: 236 SQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHK 295
Query: 888 SRENKRSQP---RVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSR 944
S+ RS+ RV++ G SR +S+E+ + R + +R SRSRS S+ +
Sbjct: 296 SKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRK 355
Query: 945 CRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIH 1004
R +S+ S R S S R + R + R + +K + +R +
Sbjct: 356 GRKRSREESRSRSRSRSKSERSRKRGSK---RDSKAGSSKKKKKEDTDRSQSRSPSRSVS 412
Query: 1005 LDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFG 1064
+ + S R N R+R+ K K + E+R+ + S
Sbjct: 413 KEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSAS------ 466
Query: 1065 SGWVSNRGRGRGNRGRGTYRSSFAYKDQNENR 1096
R R + +R R RS + ++ +R
Sbjct: 467 ----KTRSRSK-SRSRSASRSPSRSRSRSHSR 493
Score = 79.3 bits (194), Expect = 2e-14
Identities = 59/223 (26%), Positives = 100/223 (44%), Gaps = 19/223 (8%)
Query: 742 KQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTW 801
K+ + + ++ S D A+EK++ D + K K R + S S +
Sbjct: 252 KEKSRSRSHSAGKSRSKSKDQAEEKIQN--------NDNVGKPKSRSPSRHKSKSKSRSR 303
Query: 802 SPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQ 861
S + +EK+ S +E +S+S S +R R +S+S+ +K R R +
Sbjct: 304 SQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREE 363
Query: 862 SQSRSPKRDTTRESRR------SESLSPRRETSRENKRSQPRVKDSSPGE-----KSRSQ 910
S+SRS R + SR+ S++ S +++ + RSQ R S + KS S
Sbjct: 364 SRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESS 423
Query: 911 SRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSS 953
RE + + +E R+R S S+S PS R++SKS+S
Sbjct: 424 QREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSAS 466
Score = 75.1 bits (183), Expect = 5e-13
Identities = 81/302 (26%), Positives = 127/302 (42%), Gaps = 34/302 (11%)
Query: 774 SESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKD-TPQEKKRPQSPSPRRETGKESRKSQS 832
S S K + K++ SR S S + S ++ + +EK R S R + KS+S
Sbjct: 208 SGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRS 267
Query: 833 PSP-------KNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRR 885
S +N G+ KSRS S K + +S+SRS +R E R S S +
Sbjct: 268 KSKDQAEEKIQNNDNVGKPKSRSPSRHK----SKSKSRSRSQERRVEEEKRGSVSRGRSQ 323
Query: 886 ETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSP--- 942
E S RS+ R S G +SRS+SR + D +R+ +R+R+ SRSRS SRS
Sbjct: 324 EKSLRQSRSRSR---SKGGSRSRSRSRSKSKD----KRKGRKRSREESRSRSRSRSKSER 376
Query: 943 SRCRTKSKSSSFG------RIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENT 996
SR R + S G + D D R R + + R+ E +N T
Sbjct: 377 SRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGT 436
Query: 997 RKEKNDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSG 1056
+E S K + + P+ + S R+R+ + + + +R+ +
Sbjct: 437 NQETR------SRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRS 490
Query: 1057 NS 1058
+S
Sbjct: 491 HS 492
Score = 72.8 bits (177), Expect = 2e-12
Identities = 85/363 (23%), Positives = 147/363 (40%), Gaps = 46/363 (12%)
Query: 835 PKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRS 894
P + R +SRS S + +R R+S+SRS ++ RS S S R S+ RS
Sbjct: 177 PGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRS 236
Query: 895 QPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSF 954
Q R + S EKSRS S+E+ SRSRSHS S R+KSK +
Sbjct: 237 QSRSR--SKKEKSRSPSKEK------------------SRSRSHSAGKS--RSKSKDQAE 274
Query: 955 GRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSAD 1014
+I + N G R R++ + R+ + + S +
Sbjct: 275 EKIQNND----------NVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQE 324
Query: 1015 KHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRG 1074
K + K S R+R+ K K + +R E+ S +++ S R R
Sbjct: 325 KSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRS-----KSERSRK 379
Query: 1075 RGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFD 1134
RG++ SS K ++ +R Q+R P + S S+ + + +S +R+ E
Sbjct: 380 RGSKRDSKAGSSKKKKKEDTDRSQSRSP-----SRSVSKEREHAKSESSQREGRGESENA 434
Query: 1135 TPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSLKDQT 1194
+ S S+ + LP++ ++ R +++S +S + S S + ++
Sbjct: 435 GTNQETRSRSRSNSKSKPNLPSESRS----RSKSASKTRSRSKSRSRSASRSPSRSRSRS 490
Query: 1195 NQQ 1197
+ +
Sbjct: 491 HSR 493
Score = 70.1 bits (170), Expect = 1e-11
Identities = 79/322 (24%), Positives = 132/322 (40%), Gaps = 45/322 (13%)
Query: 824 GKESRKSQSPSPKNESARGR----KKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSE 879
G R+S S S + +R R +KSRS+S + + +S+SRS R ++ RS+
Sbjct: 178 GSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQ 237
Query: 880 SLS-PRRETSRENKRSQPRVKDSSPGE---KSRSQSRERESDRDGQRRERERR-TRKWSR 934
S S ++E SR + + R + S G+ KS+ Q+ E+ + D + + R +R S+
Sbjct: 238 SRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSK 297
Query: 935 SRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRW-KGRWANDGWRCPRGNDRYRKNDPEKQN 993
S+S SRS R + K S R S R + R + G R R + D K
Sbjct: 298 SKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGR 357
Query: 994 ENTRKE---------------KNDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRN 1038
+ +R+E K D+ +S K + D T++ S R+ +
Sbjct: 358 KRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKED-----TDRSQSRSPSRSVS 412
Query: 1039 PEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGN-----------RGRGTYRSSF 1087
E+ H + ++ G ++N G+ R R R N R R S
Sbjct: 413 KER---EHAKSESSQREGRGESENAGTN-QETRSRSRSNSKSKPNLPSESRSRSKSASKT 468
Query: 1088 AYKDQNENRWQNRKPLSGNSNS 1109
+ ++ +R +R P S S
Sbjct: 469 RSRSKSRSRSASRSPSRSRSRS 490
Score = 55.1 bits (131), Expect = 5e-07
Identities = 39/132 (29%), Positives = 58/132 (43%), Gaps = 12/132 (9%)
Query: 775 ESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPS 834
ES + ++K R+R+ S S K ++ R QS SP R KE ++S S
Sbjct: 363 ESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSES 422
Query: 835 PK------------NESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLS 882
+ N+ R R +S S+S + R +S+S S R ++ RS S S
Sbjct: 423 SQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRS 482
Query: 883 PRRETSRENKRS 894
P R SR + RS
Sbjct: 483 PSRSRSRSHSRS 494
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 84.3 bits (207), Expect = 8e-16
Identities = 70/264 (26%), Positives = 117/264 (44%), Gaps = 22/264 (8%)
Query: 774 SESPKDTIDKTKKPRTRRSRFHSPSTTWSPN--KDTPQEKKRPQSPSPRRETGKESRKSQ 831
S SP+ ++ + PR RSR H S + ++ +EK+R + +E KE R+S+
Sbjct: 260 SRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSR 319
Query: 832 SPSPKNESARGRKKSRSQS---------PKKDIARERRQSQSRSPKRDTTRESRRSESLS 882
S E R R + R +S ++D RER + R +RD + R
Sbjct: 320 SIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNERE 379
Query: 883 PRRETSREN---KRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTR---KWSRSR 936
RE SRE +RS+ V++ E + R R+ RD ++ ++ R+R + RSR
Sbjct: 380 KERERSRERSKEQRSRGEVEEKKHKE-DKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSR 438
Query: 937 SHSRSPS-RCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNEN 995
S SR+ R R++SK S + + R + G + R++ P K+
Sbjct: 439 SRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSR 498
Query: 996 TR---KEKNDIHLDADDPNSADKH 1016
R KE++ +D + +DKH
Sbjct: 499 KRSRSKERSHKRDHSDSKDQSDKH 522
Score = 77.8 bits (190), Expect = 7e-14
Identities = 66/255 (25%), Positives = 111/255 (43%), Gaps = 25/255 (9%)
Query: 826 ESRKSQSP----SPKNESARGRKKSR------SQSPKKDIARERRQSQSRSPKRDTTRES 875
E R+S+SP SP+ R R +S S S +++ RE+ + + ++ +E
Sbjct: 256 ERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKER 315
Query: 876 RRSES----LSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERE----- 926
RRS S L RR SRE RS+ R +D + R + RE+E++R G+RR+R+
Sbjct: 316 RRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENER-GRRRDRDYDKER 374
Query: 927 RRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRK 986
R+ R RS RS + + D+D R R + + R R RK
Sbjct: 375 GNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERK 434
Query: 987 NDPEKQNENTRKEKNDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESH 1046
+ ++ N K + + KH+N+ ++ SG RT + EK K+
Sbjct: 435 HRSRSRSRNAGKRSR-----SRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKRE 489
Query: 1047 WEENRNENSGNSWNK 1061
++ ++ S +K
Sbjct: 490 HSPSKEKSRKRSRSK 504
Score = 72.0 bits (175), Expect = 4e-12
Identities = 74/325 (22%), Positives = 139/325 (42%), Gaps = 31/325 (9%)
Query: 757 MPSSDLADEKVET----VSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKK 812
+P D++++T + + + + ID+ + R RS S S SP + +
Sbjct: 223 VPVQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHH 282
Query: 813 RPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTT 872
R S + E K + + R +++ RS+S + + R R +S+ R R +
Sbjct: 283 REGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRS 342
Query: 873 RESRRSESLSPRRETSRENKRSQPRVKD-----SSPGEKSRSQSRER------------- 914
R+ R+ + RE +EN+R + R +D + EK R +SRER
Sbjct: 343 RD-RKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEK 401
Query: 915 --ESDRDGQRRERERRTRKWSRSRSHSRSPSR-CRTKSKSSSFGRIDRDSYSPRWKGRWA 971
+ D+D +R ++R K + S SRS R R++S+S + G+ R S S +
Sbjct: 402 KHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSR-SRSKEKSSKHK 460
Query: 972 NDGWRCPRGNDRYRKNDPEKQN--ENTRKEKNDIHLDADDPNSADKHRNDCPNWITEKIN 1029
N+ + N R R + + E ++K ++ + S K R+ + K
Sbjct: 461 NESKE--KSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQ 518
Query: 1030 SGPDPRTRNPEKLKESHWEENRNEN 1054
S R R+ +ES ++++N++
Sbjct: 519 SDKHDRRRSQSIEQESQEKQHKNKD 543
Score = 50.4 bits (119), Expect = 1e-05
Identities = 42/156 (26%), Positives = 73/156 (46%), Gaps = 20/156 (12%)
Query: 775 ESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESR---KSQ 831
E D + K +++ + HS S + +++ +S S R GK SR K +
Sbjct: 405 EDKDDRRHRDDKRDSKKEKKHSRSRS---------RERKHRSRSRSRNAGKRSRSRSKEK 455
Query: 832 SPSPKNESA-RGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRE 890
S KNES + K+SRS S + + E+ + + SP ++ +R+ RS+ S +R+ S
Sbjct: 456 SSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDS 515
Query: 891 NKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERE 926
+S ++ RSQS E+ES + + E
Sbjct: 516 KDQSDKH-------DRRRSQSIEQESQEKQHKNKDE 544
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 82.8 bits (203), Expect = 2e-15
Identities = 96/422 (22%), Positives = 165/422 (39%), Gaps = 55/422 (13%)
Query: 809 QEKKRPQSPSPRRETGKESRKS-QSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSP 867
+E+ R + RRE + R++ + + E R RK+ R + ++D +ER + R
Sbjct: 54 RERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDR-- 111
Query: 868 KRDTTRESRRSESLSPRRETSRENKRSQPRVKDSS-PGEKSRSQSRERESDRDGQRRERE 926
+RD RE R+ RET RE +R + R D E+ R +ERE D +R+ +
Sbjct: 112 ERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQT 171
Query: 927 RRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGW------RCPRG 980
R R+ R R +R R R + + DR S R + R + R
Sbjct: 172 ERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRE 231
Query: 981 NDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRN-DCPNWITEKINSGPDPRTRNP 1039
DR RK + E++ + R+ ++ + D ++ R+ D E+ R R
Sbjct: 232 RDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRT 291
Query: 1040 EKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQN 1099
E+ +E+ + R +N R R R R R R +D+ + R +
Sbjct: 292 ERDRETERKRERQRERERERERN------RKRERER-ERERERERQRETERDREKERERK 344
Query: 1100 RKPLS----GNSNSSGSESFKFVE----------QQSYKRKSEQEFSFD----------T 1135
RK + + +G E + E +QS + + E+E D T
Sbjct: 345 RKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQT 404
Query: 1136 PADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSLKDQTN 1195
DR G R+ ++ S RGR ++ E+ G++ + QT+
Sbjct: 405 EKDRDGQRETEKQRERE------KDRESERGRERG-------REREKQKGRERDRERQTD 451
Query: 1196 QQ 1197
+Q
Sbjct: 452 RQ 453
Score = 82.4 bits (202), Expect = 3e-15
Identities = 78/347 (22%), Positives = 139/347 (40%), Gaps = 30/347 (8%)
Query: 768 ETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKES 827
+T Q + +K ++ +T R R ++ +E++R ++ RRE ++
Sbjct: 142 QTDGQRERERQRDAEKERERQTDRERQRQTE------RNRQKEREREKNRQERRERERQ- 194
Query: 828 RKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRET 887
R+ ++ + S RGR++ R + + + R+R+ + R +R T RE + E
Sbjct: 195 REKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASER 254
Query: 888 SRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRR-ERERRT-RKWSRSRSHSRSPSRC 945
E + + R +D R + RER++DR QRR ER+R T RK R R R R
Sbjct: 255 ETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERN 314
Query: 946 RTKSKSSSFGR---IDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKND 1002
R + + R R++ R K R + +R R+ E + + R+ + +
Sbjct: 315 RKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERE 374
Query: 1003 IHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKN 1062
D ++ D R R+ +K +E E++R+ +
Sbjct: 375 RERDRQSAREREERERD---------------RDRDRQKERERQTEKDRDGQRETEKQRE 419
Query: 1063 FGSGWVSNRGRGRG---NRGRGTYRSSFAYKDQNENRWQNRKPLSGN 1106
S RGR RG + +G R D+ R + R L N
Sbjct: 420 REKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVN 466
Score = 77.0 bits (188), Expect = 1e-13
Identities = 95/418 (22%), Positives = 164/418 (39%), Gaps = 59/418 (14%)
Query: 811 KKRPQSP-SPRRETGKESRKSQSPSPKN---ESARGRKKSRSQSPKK-DIARERRQSQSR 865
++RP S SPRR ++ K + + R R++ + Q+ ++ D RERR+ + R
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87
Query: 866 SPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQR--- 922
KRD RE +R R+T RE R + + E++R + RERE++R+G+R
Sbjct: 88 HRKRDRHRERQRDREKERERQTDRERDRQREK-------ERNRQKERERETEREGERGRD 140
Query: 923 ----------------RERERRT-RKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPR 965
+ERER+T R+ R +R R R K++ R+ R
Sbjct: 141 RQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQER-----RERERQR 195
Query: 966 WKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDCPNWIT 1025
K D R ++R R+ + E++ E + K + D ++ R
Sbjct: 196 EKENKTED-----RHSERGRERERERETETETERKRQTDRERDRQRKTERER-------- 242
Query: 1026 EKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGRGTYRS 1085
EK R E+ KE E +R+ + + + + R R R T R
Sbjct: 243 EKQAERERASERETERDKERERERDRDRDRDRRQKER--ERQTDRKRQRRTERDRETERK 300
Query: 1086 SFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYK---RKSEQEFSFDTPADRSGW 1142
+++ R +NRK E + E+ K RK +++ D +R
Sbjct: 301 RERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTG 360
Query: 1143 TSASSWAVR---KTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSLKDQTNQQ 1197
A R + D Q+ R R + ++E +T +D + +T +Q
Sbjct: 361 REGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTE-KDRDGQRETEKQ 417
Score = 73.6 bits (179), Expect = 1e-12
Identities = 68/297 (22%), Positives = 117/297 (39%), Gaps = 23/297 (7%)
Query: 678 EKSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSV 737
E+ E + E+ TE R T+ + + ++ + E ++ + E E +
Sbjct: 211 ERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDR 270
Query: 738 NADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTR-RSRFHS 796
+ D +Q T D E+ + E ++ K ++ R R R R
Sbjct: 271 DRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQ 330
Query: 797 PSTTWSPNKDTPQEKKR--PQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKD 854
T K+ +++KR R+TG+E R+ R++ R + +
Sbjct: 331 RETERDREKERERKRKRQTEMDRERNRQTGREGRRQAE----------RERERERERDRQ 380
Query: 855 IARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRER 914
ARER + R RD R+ R R+ RE ++ + R KD E+ R + RER
Sbjct: 381 SARER---EERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRE-SERGRERGRER 436
Query: 915 ESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSP----RWK 967
E + G+ R+RER+T + R RS +++ G + D P RWK
Sbjct: 437 EKQK-GRERDRERQTDR-QAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWK 491
Score = 72.4 bits (176), Expect = 3e-12
Identities = 64/306 (20%), Positives = 116/306 (37%), Gaps = 20/306 (6%)
Query: 765 EKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETG 824
E+ + E D + + R R+ + Q +K ++ E G
Sbjct: 150 ERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERG 209
Query: 825 KESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLS-- 882
+E + + + E R + R + K + RE++ + R+ +R+T R+ R
Sbjct: 210 RERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRD 269
Query: 883 ---PRRETSRENKRSQPRVKDSS-PGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSH 938
RR+ RE + + R + + E R + R+RE +R+ +R + R R+ R R
Sbjct: 270 RDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERER 329
Query: 939 SRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRK 998
R R R K + + R + R + R R +R R+ + ++Q+ R+
Sbjct: 330 QRETERDREKERER---KRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARERE 386
Query: 999 EKNDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNS 1058
E+ D D ++ R TEK G R ++ +E E R G
Sbjct: 387 ER---ERDRDRDRQKERERQ------TEKDRDG--QRETEKQREREKDRESERGRERGRE 435
Query: 1059 WNKNFG 1064
K G
Sbjct: 436 REKQKG 441
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 82.0 bits (201), Expect = 4e-15
Identities = 140/582 (24%), Positives = 226/582 (38%), Gaps = 89/582 (15%)
Query: 735 PSVNADLKQMNENSVTHCSENNMPSSDLADE-KVETVSQPSESPKDTIDKTKKPRTRRSR 793
PS +LK+ E + + S DE K + + ES ++ ++++ PR R+SR
Sbjct: 120 PSAFLELKK-EEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSR 178
Query: 794 FHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKK 853
SP SP + +E+KR S SPR T KS+SPSP E +K+ + P+
Sbjct: 179 SPSPRRRSSPVR---RERKRSHSRSPRHRT-----KSRSPSPAPE----KKEKTPELPEP 226
Query: 854 DIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRE 913
+ + Q + D + + P+ + +N + + + + P +SRS+SR
Sbjct: 227 SVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRS 286
Query: 914 RESDRDGQRRERERRTRKWSRSRSHSRSPS-------RCRTKSKSSSFGRIDRDSYSP-- 964
R R RR R SRS S R PS R RT + R S SP
Sbjct: 287 RTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVR 346
Query: 965 -RWKGRWANDGWRCPRGNDRYRK--NDPEKQNENTRKEKNDIHLDADDPNSADKHRNDCP 1021
R + + G + R R P K+ + ++ + A P +HR P
Sbjct: 347 RRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRR--RHRPSPP 404
Query: 1022 NWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGRG 1081
+ P P+TR+ ++S NR S S + SG V+ + +G R
Sbjct: 405 --------ATPPPKTRHSPTPQQS----NRTRKSRVSVSPGRTSGKVT---KHKGTEKRE 449
Query: 1082 TYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFDTPADRSG 1141
+ S A K + ++ + G ++ S V+Q+ R+ Q+ S D+
Sbjct: 450 S--PSPAPKPRKVELSESEEDKGGKMAAADS-----VQQRRQYRRQNQQSSSDS------ 496
Query: 1142 WTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGW---MKQEEETSGQD----SSLKDQT 1194
S+SS + + V+N R R S +S K+++ETS + S T
Sbjct: 497 -GSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPT 555
Query: 1195 NQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIHPQLP 1254
++ S P + ++ P P P P IQR P P
Sbjct: 556 RRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPP---IQR---RYSPSPP 609
Query: 1255 LHLHTGVPLMQVATPTSVSQGLPPPP-----PPPPPSQQVNY 1291
P + A+P PPPP P PPP ++V++
Sbjct: 610 -------PKRRTASP-------PPPPKRRASPSPPPKRRVSH 637
Score = 58.5 bits (140), Expect = 4e-08
Identities = 75/275 (27%), Positives = 104/275 (37%), Gaps = 49/275 (17%)
Query: 774 SESPKDTIDKTKKPRTRRSRFHSPSTTW---SPNKDTPQEKKRPQSPSPRRETGKESRKS 830
S SP+ K PR RR R SP T SP+ P ++R +P PRR T +
Sbjct: 530 SPSPRKR-QKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRR 588
Query: 831 QSPSPKNESAR-GRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSR 889
+SPSP+ S R+ S S PK+ R S PKR R S S P+R S
Sbjct: 589 RSPSPRRYSPPIQRRYSPSPPPKR-----RTASPPPPPKR------RASPSPPPKRRVSH 637
Query: 890 ENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKS 949
S P + SSP K RS S + R+ SRS +RSP + S
Sbjct: 638 ----SPPPKQRSSPVTKRRSPSLS----------SKHRKGSSPSRSTREARSPQPNKRHS 683
Query: 950 KSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADD 1009
S R + S SP R A+ + R+ P R+ +
Sbjct: 684 PSPR-PRAPQTSSSPPPVRRGAS--------SSPQRRQSPSPSTRPIRRVSR-----TPE 729
Query: 1010 PNSADKHRNDCPNWI-----TEKINSGPDPRTRNP 1039
P K + P + + ++ P+P + P
Sbjct: 730 PKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKP 764
Score = 55.5 bits (132), Expect = 4e-07
Identities = 58/218 (26%), Positives = 86/218 (39%), Gaps = 27/218 (12%)
Query: 754 ENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKR 813
+N SSD S SE + K R R HSPS + SP+ Q++
Sbjct: 488 QNQQSSSDSGS------SSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETS 541
Query: 814 PQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTR 873
P+ R + +R+ +SPSP R +++ + P++ + +S SP+R +
Sbjct: 542 PRGRRRRSPSPPPTRRRRSPSPAPPPRR--RRTPTPPPRRRTPSPPPRRRSPSPRRYSPP 599
Query: 874 ESRR-SESLSPRRETS-----------------RENKRSQPRVKDSSPGEKSRSQSRERE 915
RR S S P+R T+ R S P + SSP K RS S +
Sbjct: 600 IQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSK 659
Query: 916 SDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSS 953
+ R R ++ HS SP R R SSS
Sbjct: 660 HRKGSSPSRSTREARSPQPNKRHSPSP-RPRAPQTSSS 696
Score = 45.1 bits (105), Expect = 5e-04
Identities = 57/249 (22%), Positives = 87/249 (34%), Gaps = 10/249 (4%)
Query: 758 PSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSP 817
PS ++ PS PK P RR+ P + P+++ P +
Sbjct: 591 PSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTK 650
Query: 818 SPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSP---KRDTTRE 874
+ RK SPS AR + ++ SP R R S SP +R +
Sbjct: 651 RRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPS---PRPRAPQTSSSPPPVRRGASSS 707
Query: 875 SRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSR 934
+R +S SP R R+ P K QS R S E +K
Sbjct: 708 PQRRQSPSPSTRPIRRVSRT-PEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPA 766
Query: 935 SRS--HSRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPE-K 991
S S+SPS + + + S SP G + + D+ K D + K
Sbjct: 767 PPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHK 826
Query: 992 QNENTRKEK 1000
+++ +KEK
Sbjct: 827 KHKKHKKEK 835
Score = 36.6 bits (83), Expect = 0.18
Identities = 33/122 (27%), Positives = 50/122 (40%), Gaps = 11/122 (9%)
Query: 293 QEGEEKKQTSGTSNTRGSRRKPAMTTPTRRST--RNTRAETASQSQRSPISDNSGCDAP- 349
+ EK++ S + RRK +P RRS+ R R + S+S R S AP
Sbjct: 160 ESSREKRERSRSPR----RRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPE 215
Query: 350 -GNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDE 408
P L PS E ++A + + KP + + S PEK+S + E
Sbjct: 216 KKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPS---PEKNSKKEKEKE 272
Query: 409 ET 410
+T
Sbjct: 273 KT 274
Score = 33.9 bits (76), Expect = 1.2
Identities = 37/147 (25%), Positives = 57/147 (38%), Gaps = 24/147 (16%)
Query: 290 AHTQEGEEKKQTSGTSNTR---GSRRKPA--MTTPTRRSTRNTRAETASQSQRSPISDNS 344
+HT+ + S + + R RR+P+ TP RR R + RSP+
Sbjct: 294 SHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPR----HRRSRSPVRRRR 349
Query: 345 GCDAPGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSND 404
S+ SLS SS+ S ++R PK K +R PP ++L S + P +
Sbjct: 350 ------RSSASLSGSSSSSSSSRSRSPPK-KPPKRTSSPPRKTRRLSPSASPPRR----- 397
Query: 405 SVDEETAESDTSPVLEKEHQPDVDSSN 431
+P + H P SN
Sbjct: 398 ---RHRPSPPATPPPKTRHSPTPQQSN 421
Score = 33.5 bits (75), Expect = 1.5
Identities = 31/127 (24%), Positives = 52/127 (40%), Gaps = 21/127 (16%)
Query: 297 EKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNSNP-- 354
E K+ S N++ + K T P RS +R+ T S+S P ++ P
Sbjct: 255 EPKEPSPEKNSKKEKEKEK-TRPRSRSRSKSRSRTRSRS-------------PSHTRPRR 300
Query: 355 -----SLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEE 409
S S + R +P+R++ R PP ++ RS V +SS++ S
Sbjct: 301 RHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSS 360
Query: 410 TAESDTS 416
++ S S
Sbjct: 361 SSSSSRS 367
Score = 31.2 bits (69), Expect = 7.7
Identities = 31/117 (26%), Positives = 50/117 (42%), Gaps = 10/117 (8%)
Query: 311 RRKPAMTTPTRRSTRNTRA--ETASQSQRSPISDNSGCDAPGNSNPSLSVPSSAESEKQT 368
RR P++++ R+ + +R+ E S S + AP S+ V A S Q
Sbjct: 651 RRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQR 710
Query: 369 RQAPKR-----KSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVD---EETAESDTSP 417
RQ+P + V R +P +KK S + + SS+ SV E A+ +P
Sbjct: 711 RQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAP 767
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 80.1 bits (196), Expect = 1e-14
Identities = 88/315 (27%), Positives = 146/315 (46%), Gaps = 46/315 (14%)
Query: 774 SESPKDTIDKTKKPRTRRS----RFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRK 829
S S + ++++ PR RS R S + S ++ + +E+ S SPR+E+G+ +
Sbjct: 334 SHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRS--Q 391
Query: 830 SQSPSPKNESARGRK------KSRSQSPKKDIARERRQSQSRSPKRDTTRESR------R 877
S SP+ + + +R R +SRS+SP K AR+R +S+S + RD +R R
Sbjct: 392 SGSPNKQRDHSRSRSPNKARDRSRSRSPYK--ARDRSRSRSPNKARDCSRSRSPYKARDR 449
Query: 878 SESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERE--------SDRDGQR-----RE 924
S S SP + RS + +D S +SRS S+ER+ +RD +R +E
Sbjct: 450 SRSRSPNKARDHSRSRSPNKARDRS---RSRSPSKERDHSQLGSPSKERDHRRSRSPSKE 506
Query: 925 RE-RRTRKWSRSRSH--SRSPS--RCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPR 979
R+ R++R S+ R H SRSPS R R +S+S + R S SP + R +
Sbjct: 507 RQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPS-EEREHRQSRSPSK 565
Query: 980 GNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNP 1039
DR R P K+ E + + D +S + N + + +S +R+
Sbjct: 566 ERDRRRWRSPSKERERRQSRSSSEERD----HSRSRSPNKQSGYSRPRASSKEKAHSRSR 621
Query: 1040 EKLKESHWEENRNEN 1054
KE + ++R +
Sbjct: 622 TPSKEGNHSQSRTSS 636
Score = 77.4 bits (189), Expect = 9e-14
Identities = 72/226 (31%), Positives = 108/226 (47%), Gaps = 44/226 (19%)
Query: 774 SESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETG--------K 825
S SP D+++ ++R HS S SPNK +++ R +SPS R+ +
Sbjct: 440 SRSPYKARDRSRSRSPNKARDHSRSR--SPNK--ARDRSRSRSPSKERDHSQLGSPSKER 495
Query: 826 ESRKSQSPSPKNESARGRKKS------RSQSPKKDIARERRQSQS------RSPKRDTTR 873
+ R+S+SPS + + + R S RS+SP K+ R+RRQS+S RS R +
Sbjct: 496 DHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKE--RQRRQSRSPNKERDRSQSRSPSE 553
Query: 874 ESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERE--RRTRK 931
E +S SP +E R RS + ++ +SRS S ER+ R ++ R R
Sbjct: 554 EREHRQSRSPSKERDRRRWRSPSKERER---RQSRSSSEERDHSRSRSPNKQSGYSRPRA 610
Query: 932 WSRSRSHSRS--------PSRCRTKSKSS--SFGRIDRDSYSPRWK 967
S+ ++HSRS S+ RT SK S S + R SP WK
Sbjct: 611 SSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPR---SPDWK 653
Score = 74.3 bits (181), Expect = 8e-13
Identities = 97/416 (23%), Positives = 160/416 (38%), Gaps = 42/416 (10%)
Query: 716 MIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSE 775
+IP S+ + S V+ A + ++ S++ P + + T S+
Sbjct: 249 IIPSREKSYSPTEMSSRVKSYNQASTRSRPQSH----SQSRSPRRSRSGSQKRTHSRVRS 304
Query: 776 SPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSP 835
+ RTR+ S S ++ + K + QS +PRR G+ S++PS
Sbjct: 305 HSWKRNHSRARSRTRKGIL-SQMGRHSQSRSHSKGKSQNQSRTPRR--GRSHNWSRNPSK 361
Query: 836 KNESARGRKKSR------SQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSR 889
+ + R S+ S SP+K+ R SQS SP + RS + + R SR
Sbjct: 362 ERSHSHSRSSSKERDHRGSSSPRKESGR----SQSGSPNKQRDHSRSRSPNKARDRSRSR 417
Query: 890 ENKRSQPRVKDSSPGEK---SRSQSRERESDRDGQRRERERRTRKWSRS------RSHSR 940
+++ R + SP + SRS+S + DR R + R SRS RS SR
Sbjct: 418 SPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSR 477
Query: 941 SPSRCRTKSK--SSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRK 998
SPS+ R S+ S S R R S SP K R + D R P K+ + +
Sbjct: 478 SPSKERDHSQLGSPSKERDHRRSRSPS-KERQCRQSRSSSKERDHRRSRSPSKERQRRQS 536
Query: 999 EKNDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNS 1058
+ D S + R E S + R+ + + E R ++ +S
Sbjct: 537 RSPNKERDRSQSRSPSEER--------EHRQSRSPSKERDRRRWRSPSKERERRQSRSSS 588
Query: 1059 WNKNFGSGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSES 1114
++ N+ G R+S K + +R +++ S +S ES
Sbjct: 589 EERDHSRSRSPNK-----QSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKES 639
Score = 70.5 bits (171), Expect = 1e-11
Identities = 56/231 (24%), Positives = 104/231 (45%), Gaps = 9/231 (3%)
Query: 727 DQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKK 786
D++ S + + N S + PS + ++ + S+ + + +K+
Sbjct: 448 DRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSR-SPSKE 506
Query: 787 PRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKS 846
+ R+SR S ++ +E++R QS SP +E + +S S ++ +R K
Sbjct: 507 RQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKE 566
Query: 847 RSQSPKKDIARERRQSQSRSPKRD----TTRESRRSESLSPRRETSRENKRSQPRVKDSS 902
R + + ++ER + QSRS + +R + S R +S+E S+ R S
Sbjct: 567 RDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRT-PSK 625
Query: 903 PGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSS 953
G S+S++ +ESD + R+ W RS + + S S+ RT SK+SS
Sbjct: 626 EGNHSQSRTSSKESD---PSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSS 673
Score = 58.2 bits (139), Expect = 6e-08
Identities = 77/346 (22%), Positives = 135/346 (39%), Gaps = 36/346 (10%)
Query: 808 PQEKKRPQSPSPRRETGKESRKSQSPSP---KNESARGRKKSRSQSPKKDIARERRQSQS 864
P+ R +S S R K+S + S +E A ++ Q+P ++E+ + S
Sbjct: 176 PRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPS 235
Query: 865 RSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKD-SSPGEKSRSQSRERESDRDGQRR 923
S R + + + P RE S RVK + +SR QS + R
Sbjct: 236 PSSSR---KVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRS 292
Query: 924 ERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYS-PRWKGRWANDGWRCPRGND 982
++RT RS S R+ SR R++++ ++ R S S KG+ N RG
Sbjct: 293 GSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRS 352
Query: 983 RYRKNDPEKQNENTRKEKNDIHLD---------------ADDPNSADKH-RNDCPNWITE 1026
+P K+ ++ + D + PN H R+ PN +
Sbjct: 353 HNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARD 412
Query: 1027 KINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRG-NRGRGTYRS 1085
+ R+R+P K ++ +R+ N +++ +R R R N+ R RS
Sbjct: 413 R------SRSRSPYKARDR--SRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRS 464
Query: 1086 SFAYKDQNENRWQNRKPLSGNSNSS-GSESFKFVEQQSYKRKSEQE 1130
K ++ +R +R P +S GS S + ++S E++
Sbjct: 465 RSPNKARDRSR--SRSPSKERDHSQLGSPSKERDHRRSRSPSKERQ 508
Score = 46.6 bits (109), Expect = 2e-04
Identities = 45/167 (26%), Positives = 74/167 (44%), Gaps = 17/167 (10%)
Query: 768 ETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRE----- 822
E + S SP D+++ R H S SP+K+ ++++R +SPS RE
Sbjct: 530 ERQRRQSRSPNKERDRSQSRSPSEEREHRQSR--SPSKE--RDRRRWRSPSKERERRQSR 585
Query: 823 -TGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESL 881
+ +E S+S SP +S R ++ S+ +R + + S R +++ES S+S
Sbjct: 586 SSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQST 645
Query: 882 SPR-----RETSRENKRSQPRV--KDSSPGEKSRSQSRERESDRDGQ 921
PR R +R + SQ R K SS + + S D Q
Sbjct: 646 VPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQ 692
Score = 43.1 bits (100), Expect = 0.002
Identities = 89/407 (21%), Positives = 149/407 (36%), Gaps = 70/407 (17%)
Query: 796 SPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPK---NESARGRKKSRSQSPK 852
SP + P+ + P+ +S KS +P+ + A R S S
Sbjct: 3 SPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSS 62
Query: 853 KDIARERRQSQSRSPK-RDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQS 911
K + S R+P R ++R RS++ +P R ++ + D ++ + S
Sbjct: 63 KST---KSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHS 119
Query: 912 RERESDRDGQRRERERRTRKWS--RSRSHSRSP---SRCRTK------SKSSSFGR---- 956
R R R G R + +R + R R+H P SR RT S+ S+GR
Sbjct: 120 RGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTS 179
Query: 957 -IDRDSYSPRWKGRWANDGWRCPRGNDRYRKND----PEKQNENT-----RKEKNDIHLD 1006
+R PR + +R P G+ R ++ P T KEK+ D
Sbjct: 180 NRERSDSQPR---NLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKS----D 232
Query: 1007 ADDPNSADK------------HRNDCPNWITEKINSGPDPRTRN-PEKLKESHW-EENRN 1052
P+S+ K ++ P ++ ++ S TR+ P+ +S +R+
Sbjct: 233 NPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRS 292
Query: 1053 ENSGNSWNKNFGSGWVSNRGRGRGNRGRGTY---------RSSFAYKDQNENRWQNRKPL 1103
+ + ++ W N R R +G RS K QN Q+R P
Sbjct: 293 GSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQN----QSRTPR 348
Query: 1104 SGNSNSSGSESFKFVEQQSYKRKSEQEFSF---DTPADRSGWTSASS 1147
G S++ K S+ R S +E +P SG + + S
Sbjct: 349 RGRSHNWSRNPSK-ERSHSHSRSSSKERDHRGSSSPRKESGRSQSGS 394
Score = 37.7 bits (86), Expect = 0.082
Identities = 50/254 (19%), Positives = 92/254 (36%), Gaps = 30/254 (11%)
Query: 308 RGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNS----GCDAPGNSNPSLSVPSSAE 363
R R P RS +A S+S RSP + G + + PS
Sbjct: 449 RSRSRSPNKARDHSRSRSPNKARDRSRS-RSPSKERDHSQLGSPSKERDHRRSRSPSKER 507
Query: 364 SEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAESDTSPVLEKEH 423
+Q+R + K + RR R P K++ R +P K E SP E+EH
Sbjct: 508 QCRQSRSSSKERDHRRSRSPS--KERQRRQSRSPNK--------ERDRSQSRSPSEEREH 557
Query: 424 QPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERVGSSSSESCAQDLP 483
+ S + + +S +++ E + +++ + + S ++ P
Sbjct: 558 RQSRSPS---------KERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRP 608
Query: 484 VLVGEE-----GEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQISGLSQSEVK 538
+E E ++ ES+ S++ + + D + S LSQ+
Sbjct: 609 RASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTP 668
Query: 539 TDVCTVHLPNDFPT 552
+ + H P+ FP+
Sbjct: 669 SKTSS-HSPSTFPS 681
Score = 35.4 bits (80), Expect = 0.41
Identities = 41/173 (23%), Positives = 73/173 (42%), Gaps = 21/173 (12%)
Query: 753 SENNMPSSDLADEKVETVSQPSE-----SPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDT 807
S++ PS + + + S+ + SP ++ + + R HS S SPNK +
Sbjct: 546 SQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSR--SPNKQS 603
Query: 808 --------PQEKKRPQSPSPRRETG-KESRKSQSPSPKNESARGRKKSRSQSPKKDIARE 858
+EK +S +P +E +SR S S ++S R +SP R
Sbjct: 604 GYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSP----TRT 659
Query: 859 RRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQS 911
SQ+R+P + T+ S + + + +++ K + PGE+S S S
Sbjct: 660 SSLSQNRTPSK-TSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSS 711
Score = 35.0 bits (79), Expect = 0.53
Identities = 44/188 (23%), Positives = 73/188 (38%), Gaps = 18/188 (9%)
Query: 291 HTQEGEEKK-QTSGTSNTRGSRRKPA-MTTPTRRSTRNTRAETASQSQRSPISDNSGCDA 348
H + G + +T G +R S+R P+ +TP R T R AS+ R+P S G
Sbjct: 112 HQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASR-VRTPTSQQKGSRG 170
Query: 349 PGNSNPSLSVPSSAESE-----KQTRQAPKRKSVRRGRK----PPLLKKKLRSSVAAPEK 399
P S ++S+ K++ + P + R + P K + + + + EK
Sbjct: 171 KSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEK 230
Query: 400 SSSNDSVDEETAESDTS---PVLEKEHQPDVDSSNICT---VQTHVENQSANCLKSCNEQ 453
S + +S P EK + P SS + + T QS + +S
Sbjct: 231 SDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRS 290
Query: 454 IEESEKHT 461
S+K T
Sbjct: 291 RSGSQKRT 298
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 80.1 bits (196), Expect = 1e-14
Identities = 148/675 (21%), Positives = 252/675 (37%), Gaps = 100/675 (14%)
Query: 747 NSVTHCSENNMPSSDLADEKVETVSQPS---------ESPKDTIDKTKKPRTRRSRFHSP 797
+S T S + P S A + +P S + + + T+K R R +
Sbjct: 1652 SSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSAS 1711
Query: 798 STTWSPNKDTPQEKKRPQ--SPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDI 855
S+ + ++ P+ ++ P SP P ++ R+ + SP+ ++ R +S S P+
Sbjct: 1712 SSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPR--- 1768
Query: 856 ARERRQSQSRSPKRDTTRESRRS---ESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSR 912
+R +S+SR K TTR RS +S S RR+ SR R R + S G SRS +R
Sbjct: 1769 GLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGS-GYHSRSPAR 1827
Query: 913 ERESDRDGQRRERERRTRKWSRSRSHSRSP--------------------------SRCR 946
+ S +RR RT SR RS SR+ SR R
Sbjct: 1828 QESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRR 1887
Query: 947 TKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLD 1006
++S++S R R S S R + P R R P +R
Sbjct: 1888 SRSRTSPVSR--RRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSR------- 1938
Query: 1007 ADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSG 1066
P + + R+ P + S P TR + + S R+ + + +
Sbjct: 1939 --TPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRS 1996
Query: 1067 WVS--NRGRGRGNRGRGTYRSSFAYKDQN-ENRWQNRKPLSGNSNSSGSESFKFVEQQSY 1123
S R R R T R S + R ++R PL S S S + ++S
Sbjct: 1997 RTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSR-SRSPLAIRRRSR 2055
Query: 1124 KR-----KSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMK 1178
R + ++ + PA R S SS S R R+++ P +
Sbjct: 2056 SRTPRTARGKRSLTRSPPAIRRRSASGSS---------------SDRSRSATPPATRNHS 2100
Query: 1179 QEEETSGQDSSLKDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAP 1238
+S + + S P++ + M + + + PM++ G
Sbjct: 2101 GSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSP--GMLEPLGSSRTPMSVLQQAGG---- 2154
Query: 1239 LMNIQRNPFNIHPQLPLHLHTGVPLMQVATP-----TSVSQGLPPPPPPPPPSQQVNYIA 1293
++ P P++P H T VP + T++S G PPP + ++
Sbjct: 2155 --SMMDGP---GPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMS 2209
Query: 1294 SQPDGKQLQGIPSSSHVSNNMSTPVLPAPTAAPGNTGMVQGPS--SGNTSSSSHSKASNA 1351
P L + ++ + N+++ + PA +AA N + P+ + + S + A+ A
Sbjct: 2210 QVPAPVPLMSLRTAP--AANLASRI-PAASAAAMNLASARTPAIPTAVNLADSRTPAAAA 2266
Query: 1352 AVKLAESKVSVAVEA 1366
A+ LA + +VA A
Sbjct: 2267 AMNLASPRTAVAPSA 2281
Score = 75.5 bits (184), Expect = 4e-13
Identities = 108/433 (24%), Positives = 174/433 (40%), Gaps = 80/433 (18%)
Query: 783 KTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARG 842
+++ P+ RRSR + W ++ +PQ +R +S SP+R SR +Q + RG
Sbjct: 507 RSRSPQWRRSR---SAQRWGRSR-SPQ--RRGRSRSPQRPGWSRSRNTQRRGRSRSARRG 560
Query: 843 RKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSS 902
R SRS + R +S+SR+P R RS S +P R SR ++ R + +
Sbjct: 561 RSHSRSPA-------TRGRSRSRTPAR-----RGRSRSRTPARRRSRSRTPTRRRSRSRT 608
Query: 903 PGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSY 962
P + RS+SR R RTR R RS SRSP+R +S+S
Sbjct: 609 PARRGRSRSR--------TPARRRSRTRSPVRRRSRSRSPARRSGRSRSR---------- 650
Query: 963 SPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDCPN 1022
+P +GR + R P R R P +++ +R + + + R+ +
Sbjct: 651 TPARRGRSRS---RTPARRGRSRSRTPARRSGRSR-SRTPARRGRSRSRTPRRGRSRSRS 706
Query: 1023 WITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGRGT 1082
+ + P+ R + S +N++ S N +R R +R +
Sbjct: 707 LVRRGRSHSRTPQRRG--RSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSS 764
Query: 1083 YRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFDTPADRSGW 1142
RS + ++R R+ LSG+S K+KS+ TP RS
Sbjct: 765 PRS------KAKSRLSLRRSLSGSSPCP-------------KQKSQ------TPPRRSRS 799
Query: 1143 TSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSLKDQTNQQVDGSQ 1202
S+ A +T P RR R+SS P KQ+ +T + S + +V
Sbjct: 800 GSSQPKAKSRTPP--------RRSRSSSSPPP---KQKSKTPSRQSHSSSSPHPKVKSGT 848
Query: 1203 LPI--NMMQPQMN 1213
P ++ PQ N
Sbjct: 849 PPRQGSITSPQAN 861
Score = 72.0 bits (175), Expect = 4e-12
Identities = 176/799 (22%), Positives = 288/799 (36%), Gaps = 155/799 (19%)
Query: 302 SGTSNTRGSRRKPAMTTPTRRSTR---NTRAETASQSQRS--PISDNSGCDAPGNSN--- 353
SG S + + + + PT S +R ETA ++ P +++ P +
Sbjct: 1129 SGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFS 1188
Query: 354 --PSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETA 411
P P S+ K T + P R+ G ++PE N ++ +
Sbjct: 1189 PFPVQDRPESSLVFKDTLRTPPRERSGAG--------------SSPETKEQNSALPTSSQ 1234
Query: 412 ESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERVG 471
+ + V+EK +P + +H+ ++ S E E E+ A T ++
Sbjct: 1235 DEELMEVVEKSEEPAGQ------ILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQ 1288
Query: 472 SSSSESCAQDLPVLVGEEG------EVKKLENTGIEANVLCLESEISENILEKGGDPLEK 525
S +S A ++P + G E K+L N+ + N G PLE
Sbjct: 1289 SQASLE-AVEVPSMASSWGGPHFSPEHKELSNSPLRENSF--------------GSPLEF 1333
Query: 526 QDQISGLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKIT 585
++ SG +E+ T S+V + ++ P + E S+ +E+ T
Sbjct: 1334 RN--SGPLGTEMNTGF---------------SSEVKEDLNGPFLNQLETDPSLDMKEQST 1376
Query: 586 ESSLVEITEHKDFTLK-----TEELIESPKLESSEGEIIQTVDRQ---SVKSPEVQ---- 633
SS +E ++ + + I SP L++ + +T R+ S SPE++
Sbjct: 1377 RSSGHSSSELSPDAVEKAGMSSNQSISSPVLDA----VPRTPSRERSSSASSPEMKDGLP 1432
Query: 634 LLGHVETEDVEIIATCDTFGNEDFNNIQDSENNLL---------KNNLLNTKLEKSLEEK 684
+ D G +++ S + ++ ++ K+L +
Sbjct: 1433 RTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQT 1492
Query: 685 NESLTEHPRSTELP-KTHIEQIQKHFSEDNNEM-----IPMECDSFCSDQNESEVEPSVN 738
+ P S EL K Q ++ SE + + P+ S E +V+PS +
Sbjct: 1493 PRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSAS 1552
Query: 739 ADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPS 798
+ +++S ++ P + S+ SP+ +D + RRSR S
Sbjct: 1553 PQERSESDSSPDSKAKTRTP--------LRQRSRSGSSPE--VDSKSRLSPRRSRSGS-- 1600
Query: 799 TTWSPN-KDTPQEKKRPQSPS--------------PRRETGKESRKSQSPSPKNESA--- 840
SP KD P+ R QS S PRR S K + PSP+ S+
Sbjct: 1601 ---SPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTES 1657
Query: 841 ------------RGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETS 888
RG + S K RR S+S R SRRS S S ET
Sbjct: 1658 SPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETR 1717
Query: 889 RENK---RSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWS-RSRSHSRSPSR 944
R P V P EKSRS SR R S + + RR R S + R RS SR
Sbjct: 1718 SRTPPRHRRSPSVSSPEPAEKSRS-SRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSR 1776
Query: 945 CRTKSKSSSFGRIDRDSYSP-----RWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKE 999
R + K+ + R DR S R + R + R RG Y P +Q +
Sbjct: 1777 SR-REKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSS 1835
Query: 1000 KNDIHLDADDPNSADKHRN 1018
+ P S + R+
Sbjct: 1836 RRRRGRSRTPPTSRKRSRS 1854
Score = 71.6 bits (174), Expect = 5e-12
Identities = 74/281 (26%), Positives = 115/281 (40%), Gaps = 34/281 (12%)
Query: 774 SESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTP-QEKKRPQSPSPRRETGKE-SRKSQ 831
S +P +++ P RRSR +P+ TP + + R +SP RR + +R+S
Sbjct: 586 SRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSG 645
Query: 832 SPSPKNESARGRKKSRS-----QSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRE 886
+ + RGR +SR+ +S + AR +S+SR+P R RS S +PRR
Sbjct: 646 RSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPAR-----RGRSRSRTPRRG 700
Query: 887 TSREN---KRSQPRVKDSSPGEKSRSQSRERESDRDGQRRER-----ERRTRKWSRSRSH 938
SR +R + + +S S S + R QRR R E + + S RS
Sbjct: 701 RSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSR 760
Query: 939 SRSPSRCRTKSKSSSFGRIDRDSYSPRWKG----RWANDGWRCPRGNDRYRKNDPEKQNE 994
S S R + KS+ S + S P+ K R + G P+ R +
Sbjct: 761 SLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSS 820
Query: 995 NTRKEKNDIHLDADDPNSADKHRNDCPNWITEKINSGPDPR 1035
K+K+ S H + P+ K+ SG PR
Sbjct: 821 PPPKQKS-------KTPSRQSHSSSSPH---PKVKSGTPPR 851
Score = 62.8 bits (151), Expect = 2e-09
Identities = 63/229 (27%), Positives = 101/229 (44%), Gaps = 20/229 (8%)
Query: 726 SDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLA---DEKVETVSQPSESPKDTID 782
S + S S ++ + +S + S ++ S L + ++ V P+ +PK+ +
Sbjct: 2532 SSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVR 2591
Query: 783 KTKKP-------RTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSP 835
+ + P + R S S S++ S + + S S + S S SPSP
Sbjct: 2592 EGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSP 2651
Query: 836 KNESARGRKKSRSQSPKKDIARERRQSQSRSPKR--DTTRESRRSESLSPRRETSRENKR 893
+ K S PKK ERR SRSP++ D+ R+S RS S SP E R + +
Sbjct: 2652 AKPGPQALPKPAS--PKKPPPGERR---SRSPRKPIDSLRDS-RSLSYSP-VERRRPSPQ 2704
Query: 894 SQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSP 942
PR + SS E+ + + +S +R RE + + R RS SRSP
Sbjct: 2705 PSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRS-SRSP 2752
Score = 62.0 bits (149), Expect = 4e-09
Identities = 145/630 (23%), Positives = 222/630 (35%), Gaps = 138/630 (21%)
Query: 562 QPVSCPLSDLSENVESVVNEEKITESSLVEITEHKDFTLK---TEELIESPKLESSEGEI 618
Q + P S E + VV + +E +I H LK T SP++E
Sbjct: 1225 QNSALPTSSQDEELMEVVEK---SEEPAGQILSHLSSELKEMSTSNFESSPEVE------ 1275
Query: 619 IQTVDRQSVKSPEVQLLGHVETEDVEIIATCDTFGNEDFNNIQDSENNLLKNNLLNTKLE 678
+R +V Q E VE+ + ++G F+ E+ L N+ L E
Sbjct: 1276 ----ERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFS----PEHKELSNSPLR---E 1324
Query: 679 KSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVN 738
S E P TE+ +++ ED N N+ E +PS+
Sbjct: 1325 NSFGSPLEFRNSGPLGTEMNTGFSSEVK----EDLNGPF----------LNQLETDPSL- 1369
Query: 739 ADLKQMNENSVTHCSENNMP--------------SSDLADEKVETVSQPSESPKDTID-K 783
D+K+ + S H S P SS + D T S+ S + + K
Sbjct: 1370 -DMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMK 1428
Query: 784 TKKPRT--RRSRFHS-----------------------------PSTTWSPNKDTPQEKK 812
PRT RRSR S PS S +P+ K
Sbjct: 1429 DGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKA 1488
Query: 813 RPQSPSPRRETGKESRKSQSPSPKNE---SARGRKKSRSQSPKKDIARERRQSQSRSPKR 869
PQ+P PR SR SP N+ R R S S +K +AR +SRS
Sbjct: 1489 LPQTPRPR------SRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRS--- 1539
Query: 870 DTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRT 929
+++E S SP+ + DSSP K+++++ R+ R G E + ++
Sbjct: 1540 GSSQELDVKPSASPQERSE----------SDSSPDSKAKTRTPLRQRSRSGSSPEVDSKS 1589
Query: 930 RKWSRSRSHSRSPS-----RCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCP-RGNDR 983
R R SP R +++S S + + +PR R + G RG
Sbjct: 1590 RLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSP 1649
Query: 984 YRKNDPEKQNENTRKEKNDIHLDADDPNSADKHR--------NDCPNWITEK-------- 1027
+ E E+ K + P K R P +T K
Sbjct: 1650 EGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPE-LTRKARLSRRSR 1708
Query: 1028 -INSGPDPRTRNPEKLKESHWEENRN--ENSGNSWNKNFGSG----WVSNRGRGRGNRGR 1080
+S P+ R+R P + + S + E S +S + S S RGR + R
Sbjct: 1709 SASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPR 1768
Query: 1081 GTYRSSFAYKDQNENRWQNRKPLSGNSNSS 1110
G RS + + + R R+ SG+S S+
Sbjct: 1769 GLQRSR-SRSRREKTRTTRRRDRSGSSQST 1797
Score = 57.4 bits (137), Expect = 1e-07
Identities = 86/426 (20%), Positives = 157/426 (36%), Gaps = 85/426 (19%)
Query: 741 LKQMNENSVTHCSENNMPSSDLADEKVETVS-QPSESPKDTIDKTKKPRTRRSRFHSPST 799
L ++NE +E + ++D V+ S P ++ +P S S+
Sbjct: 124 LAELNEKK----NERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSS 179
Query: 800 TWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARER 859
+ SP TP++KK+ + +++ G R+S+S SP+ E + KK + +S + R+
Sbjct: 180 SRSP---TPKQKKKKK----KKDRG---RRSESSSPRRERKKSSKKKKHRSESESKKRKH 229
Query: 860 RQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERE---- 915
R +S ++ ++ +RS S +P ++ R ++ + SS +SRS+S +
Sbjct: 230 RSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTT 289
Query: 916 -------SDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRD-------- 960
S G+R E + + + + S TK SS + D+D
Sbjct: 290 ALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATR 349
Query: 961 -SYSPRWKGRW------------------------------ANDGWRCPRGNDRYRKNDP 989
S SP N DR P
Sbjct: 350 PSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSP 409
Query: 990 EKQNENTRKEKNDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTR-----NPEKLKE 1044
EK +++ E + + P +H + P E P P + +P
Sbjct: 410 EKLPQSSSSESSP---PSPQPTKVSRHASSSP----ESPKPAPAPGSHREISSSPTSKNR 462
Query: 1045 SHWEENRNENSGNSWNKNFG---SGWVSNRGRGRG----NRGRGTYRSSFAYKDQNENRW 1097
SH R+++ ++ ++ G S + RGR R RG RS + ++ RW
Sbjct: 463 SHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRW 522
Query: 1098 -QNRKP 1102
++R P
Sbjct: 523 GRSRSP 528
Score = 47.0 bits (110), Expect = 1e-04
Identities = 53/263 (20%), Positives = 93/263 (35%), Gaps = 22/263 (8%)
Query: 745 NENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPN 804
+ N + +P SD+ + T +Q S + K+ R+ S S S++ S +
Sbjct: 2489 DHNGMLSVPAPGVPHSDVGEPPASTGAQ-QPSALAALQPAKERRSSSSSSSSSSSSSSSS 2547
Query: 805 KDTPQEKKRPQSPSPRR--------ETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIA 856
+ S S E + S +P+PK GR + + +K +
Sbjct: 2548 SSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRS 2607
Query: 857 RERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERES 916
S S S ++ S S S S +S + S + PG ++ + +
Sbjct: 2608 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKK 2667
Query: 917 DRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWR 976
G+RR R R P S+S S+ ++R SP+ R
Sbjct: 2668 PPPGERRSRS------------PRKPIDSLRDSRSLSYSPVERRRPSPQPSPR-DQQSSS 2714
Query: 977 CPRGNDRYRKNDPEKQNENTRKE 999
RG+ R ++ D + R+E
Sbjct: 2715 SERGSRRGQRGDSRSPSHKRRRE 2737
Score = 46.2 bits (108), Expect = 2e-04
Identities = 37/149 (24%), Positives = 69/149 (46%), Gaps = 4/149 (2%)
Query: 272 TSTISFEHFGT-SCKGYALAHTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAE 330
T++ + +H G S + H+ GE T + + +PA + S+ ++ +
Sbjct: 2483 TTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSS 2542
Query: 331 TASQSQRSPISDNSGCDAPGNSNPSLSVPSSAESEKQTRQAP-KRKSVRRGR--KPPLLK 387
++S S S S +SG + + SL V ++ P +++VR GR +P K
Sbjct: 2543 SSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAK 2602
Query: 388 KKLRSSVAAPEKSSSNDSVDEETAESDTS 416
+K RSS ++ SSS+ S ++ S +S
Sbjct: 2603 RKRRSSSSSSSSSSSSSSSSSSSSSSSSS 2631
Score = 45.8 bits (107), Expect = 3e-04
Identities = 62/255 (24%), Positives = 95/255 (37%), Gaps = 29/255 (11%)
Query: 726 SDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTK 785
S S +P V A + + S ++ PS + S SP ++
Sbjct: 908 SPSRSSSPQPKVKAIISPRQRSH----SGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRL 963
Query: 786 KPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRET----GKESRKSQSPSPKNESAR 841
PR S SP T P Q SP P+ + G S+SP P+ +S
Sbjct: 964 LPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKS-- 1021
Query: 842 GRKKSRSQSPKKDIARERRQSQSRSP-------------KRDTTRESRRSESLSPR-RET 887
K S QS ++ S P + T RS++ SP R++
Sbjct: 1022 --KDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQS 1079
Query: 888 SRENKRSQPRVKDSSPGEKSRSQSRERE-SDRDGQRRERERRTRKWSRSRSHSRSPSRCR 946
E+ Q + + S G +SRS S E + R R++R + S SP + R
Sbjct: 1080 HSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSA--SPMLKSGMSPEQSR 1137
Query: 947 TKSKSSSFGRIDRDS 961
+S SSS+ +D +S
Sbjct: 1138 FQSDSSSYPTVDSNS 1152
Score = 39.7 bits (91), Expect = 0.022
Identities = 43/190 (22%), Positives = 75/190 (39%), Gaps = 20/190 (10%)
Query: 292 TQEGEEKKQTS---GTSNTRGSRRKPAMTTPTRRSTRNTRAETASQ-SQRSPISDNSGCD 347
+ E + K +TS SN+ +K +++ RS + R++ S+ S R +S +S C
Sbjct: 727 SSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCP 786
Query: 348 APGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVD 407
+ P S + K + P R+S PP K K P + S + S
Sbjct: 787 KQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSK------TPSRQSHSSSSP 840
Query: 408 EETAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEES---EKHTANY 464
+S T P P + + V Q +C +S + +S +H+ +
Sbjct: 841 HPKVKSGTPPRQGSITSPQANEQS-------VTPQRRSCFESSPDPELKSRTPSRHSCSG 893
Query: 465 DTEERVGSSS 474
+ RV SS+
Sbjct: 894 SSPPRVKSST 903
Score = 35.0 bits (79), Expect = 0.53
Identities = 51/185 (27%), Positives = 70/185 (37%), Gaps = 37/185 (20%)
Query: 766 KVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKK-------RPQSPS 818
K T + S S K K R S S TP + QS +
Sbjct: 807 KSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVT 866
Query: 819 PRRETGKESR-----KSQSPS-----------PKNESARGRKKSRSQSPKKDI------- 855
P+R + ES KS++PS K+ + + SRS SP+ +
Sbjct: 867 PQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPR 926
Query: 856 ARERRQSQSRSPKRDTTRES-RRSESLSPRRETSRENKRSQPRVK---DSSPGEKSRSQS 911
R S S SP R T+R + RRS S+SP S R PR SSP K + ++
Sbjct: 927 QRSHSGSSSPSPSRVTSRTTPRRSRSVSP---CSNVESRLLPRYSHSGSSSPDTKVKPET 983
Query: 912 RERES 916
R+S
Sbjct: 984 PPRQS 988
Score = 34.3 bits (77), Expect = 0.90
Identities = 61/291 (20%), Positives = 96/291 (32%), Gaps = 43/291 (14%)
Query: 1090 KDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFDTPADRSGWTSASSWA 1149
K + + + + R+ S + +S K + +S +++ TP +
Sbjct: 188 KKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKR 247
Query: 1150 VRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSLKDQTNQQVDGSQLPIN--- 1206
R T PA SRR S+ S + + ++ K T S P +
Sbjct: 248 SRSTTPAPK----SRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRR 303
Query: 1207 ------MMQPQMNVMQQQMN---AQHQPMNIFPYP--------VGVHAPLMNIQRNPFNI 1249
+P Q+ + A QP + PY P + +R+
Sbjct: 304 GEGDAPFSEPGTTSTQRPSSPETATKQPSS--PYEDKDKDKKEKSATRPSPSPERSSTGP 361
Query: 1250 HPQLPLHL----HTGVPLMQVATPTSVSQGLPPPP--------PPPPPSQQVNYIASQPD 1297
P P L H G P TP S PP PP P + +S+
Sbjct: 362 EPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESS 421
Query: 1298 GKQLQGIPSSSHVSNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKA 1348
Q S H S S+P P P APG+ + SS + + SH +A
Sbjct: 422 PPSPQPTKVSRHAS---SSPESPKPAPAPGSHREIS--SSPTSKNRSHGRA 467
Score = 33.1 bits (74), Expect = 2.0
Identities = 29/137 (21%), Positives = 50/137 (36%), Gaps = 10/137 (7%)
Query: 291 HTQEGEEKKQTSGTSNTRGSRR-------KPAMTTP---TRRSTRNTRAETASQSQRSPI 340
H E E KK+ + + R+ + TTP +RR+ R+T A++AS S S
Sbjct: 218 HRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRS 277
Query: 341 SDNSGCDAPGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKS 400
S + + PS A + AP + + P + ++P +
Sbjct: 278 RSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYED 337
Query: 401 SSNDSVDEETAESDTSP 417
D ++ SP
Sbjct: 338 KDKDKKEKSATRPSPSP 354
Score = 33.1 bits (74), Expect = 2.0
Identities = 25/108 (23%), Positives = 42/108 (38%), Gaps = 4/108 (3%)
Query: 293 QEGEEKKQTSGTSNTRG---SRRKPAMTTPTRRSTRNTRAETASQSQ-RSPISDNSGCDA 348
+ G + +T +R +RR+ TP RR +R +S+ RSP+ S +
Sbjct: 580 RRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRS 639
Query: 349 PGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAA 396
P + + A + + P R+ R R P + RS A
Sbjct: 640 PARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPA 687
Score = 32.7 bits (73), Expect = 2.6
Identities = 28/115 (24%), Positives = 47/115 (40%), Gaps = 10/115 (8%)
Query: 292 TQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGN 351
T + +T + R R P +T RS + S+S+ SP++
Sbjct: 1941 TTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRR-------R 1993
Query: 352 SNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRS-SVAAPEKSSSNDS 405
S S + S +T +R+S R R PP ++++ RS + P K S + S
Sbjct: 1994 SRSRTSPVTRRRSRSRTSPVTRRRS--RSRTPPAIRRRSRSRTPLLPRKRSRSRS 2046
Score = 32.0 bits (71), Expect = 4.5
Identities = 27/103 (26%), Positives = 49/103 (47%), Gaps = 10/103 (9%)
Query: 322 RSTRNTRAETASQSQRSPISDN---SGCDAPGNSNPSLSVP----SSAESEKQTRQAPKR 374
R + ++R+ T Q ++ D S +P S S +ES+K+ ++P
Sbjct: 175 RESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTP 234
Query: 375 KSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETA-ESDTS 416
KS R+ + +K+ RS+ AP+ ++ S ++A SDTS
Sbjct: 235 KSKRKSKDKK--RKRSRSTTPAPKSRRAHRSTSADSASSSDTS 275
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 77.8 bits (190), Expect = 7e-14
Identities = 78/257 (30%), Positives = 120/257 (46%), Gaps = 36/257 (14%)
Query: 765 EKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETG 824
+K + S+ S SP+ K RSR S + + + + R +S RR
Sbjct: 21 DKKKEQSEVSVSPR-----ASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHES 75
Query: 825 KES----RKSQSPSPKNESA-RGRKKSRSQSPKKDI--ARERRQSQSRSPKRDTTRESRR 877
K+ KS+ + K S+ +GR++ S +D +ER+ S+ RS R +RE R
Sbjct: 76 KDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRH 135
Query: 878 SESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQR-RERERRTRKWSRSR 936
R SRE K+S+ R ++ +KSRS+SRER+ R R R+R R+R SRSR
Sbjct: 136 -------RSRSRERKKSRSRSRER---KKSRSRSRERKKSRSRSRERKRRIRSRSRSRSR 185
Query: 937 SHSRSPSRCRTKSKSSS----------FGR-IDRDSYSPRWKGR-WANDGWRC-PRGNDR 983
R+ SR RT+S+S F R + R P ++GR A D R +R
Sbjct: 186 HRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLER 245
Query: 984 YRKNDPEKQNENTRKEK 1000
+K +++ E K+K
Sbjct: 246 AKKLQEQREKEMVEKQK 262
Score = 68.6 bits (166), Expect = 4e-11
Identities = 59/198 (29%), Positives = 93/198 (46%), Gaps = 16/198 (8%)
Query: 806 DTPQEKKRPQSPSPRRETGKE-SRKSQSP-SPKNESARGRKKSRSQSPKKDIARERRQSQ 863
DT ++ P+ SP R+ KE S S SP + K+ +R R +SR + K D + +S+
Sbjct: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSR 64
Query: 864 SRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRR 923
SRS +E RR ES + ++S+++K + K E S + RER + +
Sbjct: 65 SRS------KEGRRHES---KDKSSKKHKSEEHNDK-----EHSSDKGRERLNSSENGED 110
Query: 924 ERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDR 983
+R+ RK SR RSHSRS SR R S + R R K R + + R R
Sbjct: 111 RHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSR 170
Query: 984 YRKNDPEKQNENTRKEKN 1001
RK ++ + + ++
Sbjct: 171 ERKRRIRSRSRSRSRHRH 188
Score = 65.5 bits (158), Expect = 4e-10
Identities = 58/227 (25%), Positives = 94/227 (41%), Gaps = 20/227 (8%)
Query: 774 SESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQ-EKKRPQSPSPRRETGKESRKSQS 832
S++ +D + K R + + SP + R +S +R++ E RK +S
Sbjct: 4 SDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRS 63
Query: 833 PSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPK-RDTTRESRRSESLSPRRETSREN 891
S E R +S+ +S KK + E + S K R+ S E R+E
Sbjct: 64 RSRSKEGRR--HESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSR 121
Query: 892 KRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKS 951
RS R + +SRS+ R++ R +R++ R+R+ +SRS SR R R +S+S
Sbjct: 122 GRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR-RIRSRS 180
Query: 952 SSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRK 998
S R + S R R R D +K+ E R+
Sbjct: 181 RSRSRHRHRTRS---------------RSRTRSRSRDRKKRIEKPRR 212
Score = 47.8 bits (112), Expect = 8e-05
Identities = 47/191 (24%), Positives = 94/191 (49%), Gaps = 11/191 (5%)
Query: 745 NENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSP- 803
+++S H SE + +D+ E ++ SE+ +D K K+ ++ R R HS S +
Sbjct: 77 DKSSKKHKSEEHNDKEHSSDKGRERLNS-SENGEDR-HKRKERKSSRGRSHSRSRSRERR 134
Query: 804 NKDTPQEKKRPQSPS-PRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQS 862
++ +E+K+ +S S R+++ SR+ + ++ + R +SRS+S + R R +S
Sbjct: 135 HRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRS 194
Query: 863 QSRSPKRDTTR--ESRRSESLSPRRETSRENKRSQPRVKDSSPG-----EKSRSQSRERE 915
++RS RD + E R S S R S R + D+ E+++ +RE
Sbjct: 195 RTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQRE 254
Query: 916 SDRDGQRRERE 926
+ +++++E
Sbjct: 255 KEMVEKQKQQE 265
Score = 37.7 bits (86), Expect = 0.082
Identities = 47/225 (20%), Positives = 90/225 (40%), Gaps = 44/225 (19%)
Query: 901 SSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRD 960
+S E+ + DRD ++ + E + +SRS SR R + + S D +
Sbjct: 3 ASDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKS-----DNE 57
Query: 961 SYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDC 1020
R + R + +G R E ++++++K K++ H D + +S+DK R
Sbjct: 58 GRKHRSRSR-SKEGRR------------HESKDKSSKKHKSEEHNDKE--HSSDKGR--- 99
Query: 1021 PNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGR 1080
E++NS E ++ H + R + G S ++ +R R R +R R
Sbjct: 100 -----ERLNSS--------ENGEDRHKRKERKSSRGRSHSR--------SRSRERRHRSR 138
Query: 1081 GTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKR 1125
R + + + ++R S S E + + +S R
Sbjct: 139 SRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSR 183
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 76.3 bits (186), Expect = 2e-13
Identities = 94/362 (25%), Positives = 158/362 (43%), Gaps = 42/362 (11%)
Query: 639 ETEDVEIIATCDTFGNE----------DFNNIQDSENNLLKNNLLNTKLEKSLEEKNESL 688
+TE +I+T + G+E D + S NNL+ + T+ ++E +++L
Sbjct: 1636 DTEHDMVISTSPSGGSEADIEGPLPAKDIHLDLPSNNNLVSKD---TEEPLPVKESDQTL 1692
Query: 689 TE--HPRSTELPKTHIEQIQKHFSEDNNEMIPMECDSFCSDQNESE-VEPSVNADLKQMN 745
P+ + + + K D+ +E D NE++ V P + D++++
Sbjct: 1693 AALLSPKESSGGEKEVPPPPKETLPDSGFSANIE------DINEADLVRPLLPKDMERLT 1746
Query: 746 ENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSP-- 803
S+ E + +SD+ ++ S P+ + + + + F T
Sbjct: 1747 --SLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSK 1804
Query: 804 -NKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQS 862
NK+ + +K + S R K S+ S+ S K S R ++R +S K R + +S
Sbjct: 1805 KNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTS-ESRSRARKRSSKSKSHRSQTRS 1863
Query: 863 QSRSPKRDTTRESRRSESLSP-RRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQ 921
+SRS +R R S RS S S RR S+E ++ P+ + KSR + R+R S RD +
Sbjct: 1864 RSRSRRR---RRSSRSRSKSRGRRSVSKEKRKRSPKHRS-----KSRERKRKRSSSRDNR 1915
Query: 922 RRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGN 981
+ R R RSRSH+ PSR R +S S GR S SP + R + R P
Sbjct: 1916 KTVRARSRTPSRRSRSHT--PSRRR---RSRSVGRRRSFSISPSRRSRTPSRRSRTPSRR 1970
Query: 982 DR 983
R
Sbjct: 1971 SR 1972
Score = 68.2 bits (165), Expect = 6e-11
Identities = 56/221 (25%), Positives = 100/221 (45%), Gaps = 11/221 (4%)
Query: 727 DQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKK 786
++++ E E ++ L+ ++ S S + ++ + + S+S +
Sbjct: 1808 NRDKGEKEKKRDSSLRSRSKRSK---SSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSR 1864
Query: 787 PRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKS 846
R+RR R S S + S + + ++KR +SP R ++ + RK S ++ R R ++
Sbjct: 1865 SRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRT 1924
Query: 847 RSQSPKKDIARERRQSQSRSPKRD-TTRESRRSESLSPRRETSRENKRSQPRVKDSSPGE 905
S+ + RR+S+S +R + SRRS + S R T R+ R + +P
Sbjct: 1925 PSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSR-RSRTPSR 1983
Query: 906 KSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCR 946
+SR+ SR + R RR+R R RS S SP R R
Sbjct: 1984 RSRTPSRRSRTP------SRRRRSRSVVRRRSFSISPVRLR 2018
Score = 67.0 bits (162), Expect = 1e-10
Identities = 62/205 (30%), Positives = 100/205 (48%), Gaps = 21/205 (10%)
Query: 778 KDTIDKTKKPRTR-----RSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQS 832
KDT +K+KK + R + S + S + + K R ++ R K S KS+S
Sbjct: 1797 KDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKS 1856
Query: 833 ----PSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPK-RDTTRESRRSESLSPRRET 887
++ S R R+ SRS+S + ++ + RSPK R +RE +R +R +
Sbjct: 1857 HRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKR------KRSS 1910
Query: 888 SRENKRSQPRVKDSSPGEKSRSQ--SRERESDRDGQRRERERRTRKWSRSRS-HSRSPSR 944
SR+N+++ R + +P +SRS SR R S G+RR + SR+ S SR+PSR
Sbjct: 1911 SRDNRKTV-RARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSR 1969
Query: 945 CRTKSKSSSFGRIDRDSYSPRWKGR 969
R+++ S R S +P + R
Sbjct: 1970 -RSRTPSRRSRTPSRRSRTPSRRSR 1993
Score = 59.7 bits (143), Expect = 2e-08
Identities = 61/232 (26%), Positives = 103/232 (44%), Gaps = 21/232 (9%)
Query: 729 NESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPR 788
+E + + + +K +E S + + + D + + S+ S+S + K
Sbjct: 1784 SEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSES 1843
Query: 789 TRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRS 848
R+R S + ++ + + R + S R + R+S S + S + R KSR
Sbjct: 1844 RSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRE 1903
Query: 849 QSPKKDIARERRQS---QSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGE 905
+ K+ +R+ R++ +SR+P SRRS S +P R R + R SP
Sbjct: 1904 RKRKRSSSRDNRKTVRARSRTP-------SRRSRSHTPSRRR-RSRSVGRRRSFSISPSR 1955
Query: 906 KSRSQSRERES----DRDGQRRER--ERRTRKWSRSRSHSRSPSRCRTKSKS 951
+SR+ SR + R RR R RR+R SR SR+PSR R +S+S
Sbjct: 1956 RSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR---RSRTPSR-RRRSRS 2003
Score = 58.2 bits (139), Expect = 6e-08
Identities = 97/384 (25%), Positives = 144/384 (37%), Gaps = 63/384 (16%)
Query: 580 NEEKITESSLVEITEHKDFTLKTEEL--IESPKLESSEGEIIQTVDRQSVKSPEVQLL-- 635
N E I E+ LV KD T IE P L S G DR S SP V +
Sbjct: 1724 NIEDINEADLVRPLLPKDMERLTSLRAGIEGPLLASDVGR-----DR-SAASPVVSSMPE 1777
Query: 636 -----GHVETEDVEI-IATCDTFGNEDFNNIQDS-ENNLLKNNLLNTKLEKSLEEKNESL 688
E +D EI + DT N +D E +++ L ++ ++S +++S
Sbjct: 1778 RASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSR 1837
Query: 689 TEHPRSTELPKTHIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENS 748
S + + + H S+ + +++S SV+ + ++ +
Sbjct: 1838 KRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKH 1897
Query: 749 VTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTP 808
+ E S D + +TV S +P +RRSR H+PS
Sbjct: 1898 RSKSRERKRKRSSSRDNR-KTVRARSRTP-----------SRRSRSHTPSRR-------- 1937
Query: 809 QEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPK 868
RR R+S S SP S ++SR+ S +SR+P
Sbjct: 1938 -----------RRSRSVGRRRSFSISPSRRSRTPSRRSRTPS-----------RRSRTPS 1975
Query: 869 RDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRR-ERER 927
R + SRRS + S R T +RS+ V+ S S S R R S +RR R
Sbjct: 1976 RRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRS---FSISPVRLRRSRTPLRRRFSRSP 2032
Query: 928 RTRKWSRSRSHSRSPSRCRTKSKS 951
RK SRS RSP R K+
Sbjct: 2033 IRRKRSRSSERGRSPKRLTDLDKA 2056
Score = 47.0 bits (110), Expect = 1e-04
Identities = 76/367 (20%), Positives = 139/367 (37%), Gaps = 26/367 (7%)
Query: 726 SDQNESEVE-----PSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDT 780
S +E+++E ++ DL N N V+ +E +P + +D+ + + P ES
Sbjct: 1648 SGGSEADIEGPLPAKDIHLDLPS-NNNLVSKDTEEPLPVKE-SDQTLAALLSPKESSGGE 1705
Query: 781 IDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESA 840
+ P+ P + +S N + E + P+ S ++ P S
Sbjct: 1706 KEVPPPPKETL-----PDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGPLLASD 1760
Query: 841 RGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKD 900
GR +S + SP ER S K D + ++ ++ +K + + +D
Sbjct: 1761 VGRDRSAA-SPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRD 1819
Query: 901 SSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRD 960
SS +S+ R + S+ ++R E R+R +R RS R +T+S+S S R
Sbjct: 1820 SSLRSRSK---RSKSSEHKSRKRTSESRSR--ARKRSSKSKSHRSQTRSRSRSRRRRRSS 1874
Query: 961 SYSPRWKGRWA---NDGWRCP----RGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSA 1013
+ +GR + R P + +R RK + N T + ++ ++
Sbjct: 1875 RSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTP 1934
Query: 1014 DKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGR 1073
+ R + P R+R P + + +R S S + S S R R
Sbjct: 1935 SRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTP-SRRSRTPSRRSRTPSRRSR 1993
Query: 1074 GRGNRGR 1080
R R
Sbjct: 1994 TPSRRRR 2000
Score = 32.3 bits (72), Expect = 3.4
Identities = 32/155 (20%), Positives = 64/155 (41%), Gaps = 28/155 (18%)
Query: 815 QSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSR------SPK 868
Q S R G+ + ++ +P N++ +RS P ++I ++ + S K
Sbjct: 22 QELSSGRNEGQLNGETNTPIEGNQAGDAAASARSL-PNEEIVQKIEEVLSGVLDTELRYK 80
Query: 869 RDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERR 928
D SR+S +S + + + D P +KS+ + + +++
Sbjct: 81 PDLKEGSRKSRCVSVQTDPT-----------DEIPTKKSKKHKKHKN----------KKK 119
Query: 929 TRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYS 963
+K + + + R P +K+KS G ID +S S
Sbjct: 120 KKKKEKEKKYKRQPEESESKTKSHDDGNIDLESDS 154
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 76.3 bits (186), Expect = 2e-13
Identities = 94/362 (25%), Positives = 158/362 (43%), Gaps = 42/362 (11%)
Query: 639 ETEDVEIIATCDTFGNE----------DFNNIQDSENNLLKNNLLNTKLEKSLEEKNESL 688
+TE +I+T + G+E D + S NNL+ + T+ ++E +++L
Sbjct: 1636 DTEHDMVISTSPSGGSEADIEGPLPAKDIHLDLPSNNNLVSKD---TEEPLPVKESDQTL 1692
Query: 689 TE--HPRSTELPKTHIEQIQKHFSEDNNEMIPMECDSFCSDQNESE-VEPSVNADLKQMN 745
P+ + + + K D+ +E D NE++ V P + D++++
Sbjct: 1693 AALLSPKESSGGEKEVPPPPKETLPDSGFSANIE------DINEADLVRPLLPKDMERLT 1746
Query: 746 ENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSP-- 803
S+ E + +SD+ ++ S P+ + + + + F T
Sbjct: 1747 --SLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSK 1804
Query: 804 -NKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQS 862
NK+ + +K + S R K S+ S+ S K S R ++R +S K R + +S
Sbjct: 1805 KNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTS-ESRSRARKRSSKSKSHRSQTRS 1863
Query: 863 QSRSPKRDTTRESRRSESLSP-RRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQ 921
+SRS +R R S RS S S RR S+E ++ P+ + KSR + R+R S RD +
Sbjct: 1864 RSRSRRR---RRSSRSRSKSRGRRSVSKEKRKRSPKHRS-----KSRERKRKRSSSRDNR 1915
Query: 922 RRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGN 981
+ R R RSRSH+ PSR R +S S GR S SP + R + R P
Sbjct: 1916 KTVRARSRTPSRRSRSHT--PSRRR---RSRSVGRRRSFSISPSRRSRTPSRRSRTPSRR 1970
Query: 982 DR 983
R
Sbjct: 1971 SR 1972
Score = 68.2 bits (165), Expect = 6e-11
Identities = 56/221 (25%), Positives = 100/221 (45%), Gaps = 11/221 (4%)
Query: 727 DQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKK 786
++++ E E ++ L+ ++ S S + ++ + + S+S +
Sbjct: 1808 NRDKGEKEKKRDSSLRSRSKRSK---SSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSR 1864
Query: 787 PRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKS 846
R+RR R S S + S + + ++KR +SP R ++ + RK S ++ R R ++
Sbjct: 1865 SRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRT 1924
Query: 847 RSQSPKKDIARERRQSQSRSPKRD-TTRESRRSESLSPRRETSRENKRSQPRVKDSSPGE 905
S+ + RR+S+S +R + SRRS + S R T R+ R + +P
Sbjct: 1925 PSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSR-RSRTPSR 1983
Query: 906 KSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCR 946
+SR+ SR + R RR+R R RS S SP R R
Sbjct: 1984 RSRTPSRRSRTP------SRRRRSRSVVRRRSFSISPVRLR 2018
Score = 67.0 bits (162), Expect = 1e-10
Identities = 62/205 (30%), Positives = 100/205 (48%), Gaps = 21/205 (10%)
Query: 778 KDTIDKTKKPRTR-----RSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQS 832
KDT +K+KK + R + S + S + + K R ++ R K S KS+S
Sbjct: 1797 KDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKS 1856
Query: 833 ----PSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPK-RDTTRESRRSESLSPRRET 887
++ S R R+ SRS+S + ++ + RSPK R +RE +R +R +
Sbjct: 1857 HRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKR------KRSS 1910
Query: 888 SRENKRSQPRVKDSSPGEKSRSQ--SRERESDRDGQRRERERRTRKWSRSRS-HSRSPSR 944
SR+N+++ R + +P +SRS SR R S G+RR + SR+ S SR+PSR
Sbjct: 1911 SRDNRKTV-RARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSR 1969
Query: 945 CRTKSKSSSFGRIDRDSYSPRWKGR 969
R+++ S R S +P + R
Sbjct: 1970 -RSRTPSRRSRTPSRRSRTPSRRSR 1993
Score = 59.7 bits (143), Expect = 2e-08
Identities = 61/232 (26%), Positives = 103/232 (44%), Gaps = 21/232 (9%)
Query: 729 NESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPR 788
+E + + + +K +E S + + + D + + S+ S+S + K
Sbjct: 1784 SEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSES 1843
Query: 789 TRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRS 848
R+R S + ++ + + R + S R + R+S S + S + R KSR
Sbjct: 1844 RSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRE 1903
Query: 849 QSPKKDIARERRQS---QSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGE 905
+ K+ +R+ R++ +SR+P SRRS S +P R R + R SP
Sbjct: 1904 RKRKRSSSRDNRKTVRARSRTP-------SRRSRSHTPSRRR-RSRSVGRRRSFSISPSR 1955
Query: 906 KSRSQSRERES----DRDGQRRER--ERRTRKWSRSRSHSRSPSRCRTKSKS 951
+SR+ SR + R RR R RR+R SR SR+PSR R +S+S
Sbjct: 1956 RSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR---RSRTPSR-RRRSRS 2003
Score = 58.2 bits (139), Expect = 6e-08
Identities = 97/384 (25%), Positives = 144/384 (37%), Gaps = 63/384 (16%)
Query: 580 NEEKITESSLVEITEHKDFTLKTEEL--IESPKLESSEGEIIQTVDRQSVKSPEVQLL-- 635
N E I E+ LV KD T IE P L S G DR S SP V +
Sbjct: 1724 NIEDINEADLVRPLLPKDMERLTSLRAGIEGPLLASDVGR-----DR-SAASPVVSSMPE 1777
Query: 636 -----GHVETEDVEI-IATCDTFGNEDFNNIQDS-ENNLLKNNLLNTKLEKSLEEKNESL 688
E +D EI + DT N +D E +++ L ++ ++S +++S
Sbjct: 1778 RASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSR 1837
Query: 689 TEHPRSTELPKTHIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENS 748
S + + + H S+ + +++S SV+ + ++ +
Sbjct: 1838 KRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKH 1897
Query: 749 VTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTP 808
+ E S D + +TV S +P +RRSR H+PS
Sbjct: 1898 RSKSRERKRKRSSSRDNR-KTVRARSRTP-----------SRRSRSHTPSRR-------- 1937
Query: 809 QEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPK 868
RR R+S S SP S ++SR+ S +SR+P
Sbjct: 1938 -----------RRSRSVGRRRSFSISPSRRSRTPSRRSRTPS-----------RRSRTPS 1975
Query: 869 RDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRR-ERER 927
R + SRRS + S R T +RS+ V+ S S S R R S +RR R
Sbjct: 1976 RRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRS---FSISPVRLRRSRTPLRRRFSRSP 2032
Query: 928 RTRKWSRSRSHSRSPSRCRTKSKS 951
RK SRS RSP R K+
Sbjct: 2033 IRRKRSRSSERGRSPKRLTDLDKA 2056
Score = 47.0 bits (110), Expect = 1e-04
Identities = 76/367 (20%), Positives = 139/367 (37%), Gaps = 26/367 (7%)
Query: 726 SDQNESEVE-----PSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDT 780
S +E+++E ++ DL N N V+ +E +P + +D+ + + P ES
Sbjct: 1648 SGGSEADIEGPLPAKDIHLDLPS-NNNLVSKDTEEPLPVKE-SDQTLAALLSPKESSGGE 1705
Query: 781 IDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESA 840
+ P+ P + +S N + E + P+ S ++ P S
Sbjct: 1706 KEVPPPPKETL-----PDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGPLLASD 1760
Query: 841 RGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKD 900
GR +S + SP ER S K D + ++ ++ +K + + +D
Sbjct: 1761 VGRDRSAA-SPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRD 1819
Query: 901 SSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRD 960
SS +S+ R + S+ ++R E R+R +R RS R +T+S+S S R
Sbjct: 1820 SSLRSRSK---RSKSSEHKSRKRTSESRSR--ARKRSSKSKSHRSQTRSRSRSRRRRRSS 1874
Query: 961 SYSPRWKGRWA---NDGWRCP----RGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSA 1013
+ +GR + R P + +R RK + N T + ++ ++
Sbjct: 1875 RSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTP 1934
Query: 1014 DKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGR 1073
+ R + P R+R P + + +R S S + S S R R
Sbjct: 1935 SRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTP-SRRSRTPSRRSRTPSRRSR 1993
Query: 1074 GRGNRGR 1080
R R
Sbjct: 1994 TPSRRRR 2000
Score = 32.3 bits (72), Expect = 3.4
Identities = 32/155 (20%), Positives = 64/155 (41%), Gaps = 28/155 (18%)
Query: 815 QSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSR------SPK 868
Q S R G+ + ++ +P N++ +RS P ++I ++ + S K
Sbjct: 22 QELSSGRNEGQLNGETNTPIEGNQAGDAAASARSL-PNEEIVQKIEEVLSGVLDTELRYK 80
Query: 869 RDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERR 928
D SR+S +S + + + D P +KS+ + + +++
Sbjct: 81 PDLKEGSRKSRCVSVQTDPT-----------DEIPTKKSKKHKKHKN----------KKK 119
Query: 929 TRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYS 963
+K + + + R P +K+KS G ID +S S
Sbjct: 120 KKKKEKEKKYKRQPEESESKTKSHDDGNIDLESDS 154
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 76.3 bits (186), Expect = 2e-13
Identities = 170/831 (20%), Positives = 313/831 (37%), Gaps = 104/831 (12%)
Query: 255 TEVLPLISSVLPRTIFPT-STISFEHFGTSCKGYALAHTQEGEEKKQTSGTSNTRGSRRK 313
T +LP+ S+ I T S+ S+ + + +++ + ++S S +R SR +
Sbjct: 641 THLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSR 700
Query: 314 PAMTTPTR-RSTRNTRAETASQSQRS----PISDNSGCDAPGNSNPSLSVPSSAESEKQT 368
+ TR RS ++ + + S S RS SD+S C +S S+S ++++
Sbjct: 701 SYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSR-SSSYTSISSDDGRRAKRRL 759
Query: 369 RQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAESDTSPVLEKEHQPDVD 428
R + K+ SV + +K L S K S + +ES +S ++ D +
Sbjct: 760 RSSGKKNSVSHKKHSSSSEKTLHSKYV---KGRDRSSCVRKYSESRSS----LDYSSDSE 812
Query: 429 SSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERVGSSSSESCAQDLPVLVGE 488
S++ Q+ E + ++ + + +E + +E S + ++L +
Sbjct: 813 QSSVQATQSAQEKEKQGQMERTHNK-QEKNRGEEKSKSERECPHSKKRTLKENLSDHLRN 871
Query: 489 EGEVKKLENTGIEANVLCLESEISENILEKG-GDPLEKQDQISGLSQSEVKTDVCTVH-- 545
+ K+ G + + ES ++ + D D+ G + S+ +++V +H
Sbjct: 872 GSKPKRKNYAGSKWDS---ESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIK 928
Query: 546 ------------LPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLVEIT 593
LP+D +S+ + S SEN + K ++
Sbjct: 929 VKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLK-- 986
Query: 594 EHKDFTLKTEELIES------------------PKLESSEGEIIQTVDRQ-SVKSPEVQL 634
++ T K +E ++ P LE E E + D+Q + +S E ++
Sbjct: 987 --REHTKKVKEKLKGKKDKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQVTQESKEKKV 1044
Query: 635 LGHVETEDVEIIATC-----DTFGNEDFNNIQDSENNLLKNN--LLNTKLEKSLEEKNES 687
+ ET I+ T D G D + + K++ L + + EE
Sbjct: 1045 SENNETIKDNILKTEKSSEEDLSGKHDTVTVSSDLDQFTKDDSKLSISPTALNTEENVAC 1104
Query: 688 LTEHPRSTELPKTHIEQIQKHFSEDNNEMIPMECDSFCSDQNESEV------EPSVNADL 741
L E +E + + ++DN E+ + S + S + P +N L
Sbjct: 1105 LQNIQHVEESVPNGVEDVLQ--TDDNMEICTPDRSSPAKVEETSPLGNARLDTPDINIVL 1162
Query: 742 KQ-----------------MNENSVT-HCSENNMPSSDLADEKVETVSQP--SESPKDTI 781
KQ M+E+ V + + S+ LA T + +S + I
Sbjct: 1163 KQDMATEHPQAEVVKQESSMSESKVLGEVGKQDSSSASLASAGESTGKKEVAEKSQINLI 1222
Query: 782 DKTKKPRTRRSRFHSPSTTWSPNKD----TPQEKKRPQSPSPRRETGKESRKSQSPSPKN 837
DK KP +P+ S + T + +PQ ++ + R
Sbjct: 1223 DKKWKPLQGVGNLAAPNAATSSAVEVKVLTTVPEMKPQGLRIEIKSKNKVRPGSLFDEVR 1282
Query: 838 ESARGRKKSRSQSPKKDIARERRQ--SQSRSPKRDTTRESRRSESLSPRRETSRENKRSQ 895
++AR ++ R+Q D R SQSRSP R ++ +S + R S + RS+
Sbjct: 1283 KTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRT--RSVSYSHSRSR 1340
Query: 896 PRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFG 955
R SS +S S+SR R G+ R R R + R+ SRS SR + S
Sbjct: 1341 SRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSR 1400
Query: 956 RIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLD 1006
DSY R + R R R + +R +++ + R +D D
Sbjct: 1401 SYTYDSYYSRSRSR-----SRSQRSDSYHRGRSYNRRSRSCRSYGSDSESD 1446
Score = 73.6 bits (179), Expect = 1e-12
Identities = 147/666 (22%), Positives = 254/666 (38%), Gaps = 91/666 (13%)
Query: 319 PTRRSTRNTRAETASQSQRSPISDNSGCDAPGNSNPSLSVPSSAESEKQTRQAPKRKSVR 378
P R++ ++ ++ S S+R ++ NS D S+PS S E + T + S
Sbjct: 875 PKRKNYAGSKWDSESNSERD-VTKNSKND----SHPS----SDKEEGEATSDSESEVSEI 925
Query: 379 RGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAESDTSPVLEKEHQPDVDSSNICTVQTH 438
+ P K +S+ P+ + + S + T+ SD+ E +N Q H
Sbjct: 926 HIKVKPTTKSSTNTSL--PDDNGAWKSSKQRTSTSDS------EGSCSNSENNRGKPQKH 977
Query: 439 VENQSANCLKSCNEQIEESEKHTANYDTEERVGSSSSESCAQDLPVLVGEEGEV----KK 494
N + ++++E K + ++ ++ P+ GEE E K+
Sbjct: 978 KHGSKENLKREHTKKVKEKLKGKKD---KKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQ 1034
Query: 495 LENTGIEANVLCLESEISENILEKGGDPLEKQDQISGLSQSEVKTDVCTVHLPNDFPTCL 554
+ E V I +NIL+ ++ +SG K D TV + +D
Sbjct: 1035 VTQESKEKKVSENNETIKDNILK---TEKSSEEDLSG------KHD--TVTVSSDLDQFT 1083
Query: 555 TSESKVYQPVSCPLSDLSENVESVVNEEKITESSLVEITEHKDFTLKTEELIESPKLESS 614
+SK+ +S + ENV + N + + ES + + L+T++ +E
Sbjct: 1084 KDDSKL--SISPTALNTEENVACLQNIQHVEES----VPNGVEDVLQTDDNME------- 1130
Query: 615 EGEIIQTVDRQS-VKSPEVQLLGH--VETEDVEIIATCDTFGNEDFNNIQDSENNLLKNN 671
I T DR S K E LG+ ++T D+ I+ D + E+++ ++
Sbjct: 1131 ----ICTPDRSSPAKVEETSPLGNARLDTPDINIVLKQDMATEHPQAEVVKQESSMSESK 1186
Query: 672 LL-----NTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIPMECDSFCS 726
+L SL ES + + + I++ K N P S
Sbjct: 1187 VLGEVGKQDSSSASLASAGESTGKKEVAEKSQINLIDKKWKPLQGVGNLAAPNAATS--- 1243
Query: 727 DQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKK 786
S VE V + +M + ++E S+ P D+ +K
Sbjct: 1244 ----SAVEVKVLTTVPEMKPQGL----------------RIEIKSKNKVRPGSLFDEVRK 1283
Query: 787 PRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKS 846
T R + S ++ TP QS SP R K KS+ + + R +S
Sbjct: 1284 --TARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRS 1341
Query: 847 RSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRR-ETSRENKRSQPRVKDSSPGE 905
RS + R R S+SRS + +R RS S S R ++ R + RS+ R P
Sbjct: 1342 RSSTSS---YRSRSYSRSRS-RGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHS 1397
Query: 906 KSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPR 965
+SRS + + R + R R +R+ + R RS++R CR+ S R SP
Sbjct: 1398 RSRSYTYDSYYSR-SRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPS 1456
Query: 966 WKGRWA 971
R++
Sbjct: 1457 ESSRYS 1462
Score = 52.8 bits (125), Expect = 2e-06
Identities = 69/247 (27%), Positives = 100/247 (40%), Gaps = 41/247 (16%)
Query: 727 DQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKK 786
D + SE P +++++ P S K + +S P S D +++
Sbjct: 355 DDDSSETPPHWKEEMQRLRAYR---------PPSGEKWSKGDKLSDPCSSRWD--ERSLS 403
Query: 787 PRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKS 846
R+R ++ + S + + KKR R+ K K + K+ + K
Sbjct: 404 QRSRSWSYNGYYSDLSTARHSGHHKKR-------RKEKKVKHKKKGKKQKHCRRHKQTKK 456
Query: 847 RSQSPKKDIARERRQSQSRSPKRDTTRE-SRRSESLSPRRETSRENKRSQPRVKDS---- 901
R DI E +S +R K RE S RS SLS + R+ +S V+ S
Sbjct: 457 RRILIPSDI--ESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHS 514
Query: 902 ---SPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRID 958
S KS SQS R S R+R S+S SHSRS S+ R+ SKS G
Sbjct: 515 SRDSYRSKSHSQSYSRGSS----------RSRTASKSSSHSRSRSKSRSSSKS---GHRK 561
Query: 959 RDSYSPR 965
R S SPR
Sbjct: 562 RASKSPR 568
Score = 51.2 bits (121), Expect = 7e-06
Identities = 98/484 (20%), Positives = 173/484 (35%), Gaps = 72/484 (14%)
Query: 746 ENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRF--HSPSTTWSP 803
++S+TH S ++ S + S+ + K + + ++R S H + SP
Sbjct: 508 QSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSP 567
Query: 804 NKDTPQ-EKKRPQSPSPRRETGKESRK----------------SQSPSPKNESARGRKKS 846
K Q + +P P R T ++ S SP P S
Sbjct: 568 RKTASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPP----------S 617
Query: 847 RSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEK 906
R + +K + Q K + + SL+ +ET + + R K+S +
Sbjct: 618 RWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHK-REKNSESDQS 676
Query: 907 SRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPR- 965
+ S+ +R S+ + R R R+R +SRS + SRS + ++S+S S R+ YS
Sbjct: 677 TYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHS 736
Query: 966 -------WKGRWANDGWRCPRG-NDRYRKNDPEKQNENTRKEK----------------- 1000
+ ++DG R R +KN + ++ EK
Sbjct: 737 QCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVR 796
Query: 1001 --NDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNS 1058
++ D + +++ EK G RT N ++ K E++++E
Sbjct: 797 KYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQE-KNRGEEKSKSERECPH 855
Query: 1059 WNKNFGSGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSG------- 1111
K +S+ R R Y S + N R + + + SS
Sbjct: 856 SKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEAT 915
Query: 1112 SESFKFVEQQSYKRKSEQEFSFDT--PADRSGWTSASSWAVRKTLPADVQNYYSRRGRNS 1169
S+S V + K K + S +T P D W S+ ++T +D + S N
Sbjct: 916 SDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSK----QRTSTSDSEGSCSNSENNR 971
Query: 1170 SGPQ 1173
PQ
Sbjct: 972 GKPQ 975
Score = 49.3 bits (116), Expect = 3e-05
Identities = 116/558 (20%), Positives = 202/558 (36%), Gaps = 96/558 (17%)
Query: 662 DSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFSED--NNEMIPM 719
DS +N ++ + E LE + +H R ++ ++ + + SE+ N +
Sbjct: 199 DSSSNSSSSS--ESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSEEPRNKHAMNP 256
Query: 720 ECDSFCSDQNESE-VEPSVNADLKQMNENSVTHCSEN------NMPSSDLADE-KVETVS 771
+ S SD NE V+ S + + + EN +MP E K+ V+
Sbjct: 257 KGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLRRDMPVVTAEPEPKIPDVA 316
Query: 772 QPSESPKDTIDKTKKPRTRRS--RFHSPSTTWS-------PNKDTP------QEKKRPQS 816
K ++ K+ + R R+H+P + S + +TP ++ R
Sbjct: 317 PIVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDSSETPPHWKEEMQRLRAYR 376
Query: 817 PSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPK---KDIARERRQSQSRSPKRDTT- 872
P + K + S S + + ++SRS S D++ R + +++
Sbjct: 377 PPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKV 436
Query: 873 ---------RESRRSESLSPRR-------ETSRENKRSQPRVKDSSPGEKSRSQSRERES 916
+ RR + RR E+S+ + R D +S S S S
Sbjct: 437 KHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSS 496
Query: 917 DRDGQRRERERRT----------RKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRW 966
RD + +++ ++ R S S+S+SR SR RT SKSSS R S S
Sbjct: 497 KRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSK 556
Query: 967 KGRWANDGWRCPRGNDRYRKNDPEK---------QNENTRKE----KNDIHLDADDPNSA 1013
G + + +N P K QNEN + +N + D
Sbjct: 557 SGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPP 616
Query: 1014 DKHRNDCPNW--ITEKINSG--------PDPRTRNPEKLKES------HWEENRNENSGN 1057
+ + W E+I P T + +KE+ H E +E+ +
Sbjct: 617 SRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQS 676
Query: 1058 SWNK-NFGSGWVSNRGRGRGNRGRGTYR---------SSFAYKDQNENRWQNRKPLSGNS 1107
+++K + S S R R R +R R R SS + +R +R S +S
Sbjct: 677 TYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHS 736
Query: 1108 NSSGSESFKFVEQQSYKR 1125
S S S+ + +R
Sbjct: 737 QCSRSSSYTSISSDDGRR 754
Score = 47.0 bits (110), Expect = 1e-04
Identities = 93/480 (19%), Positives = 171/480 (35%), Gaps = 60/480 (12%)
Query: 751 HCSENNMPSSD--LADEKVETVSQPSESPKDTIDKTKKPRTRR-SRFHSPSTTWS-PNKD 806
HC + L +E+ + K + D+ + R+ S HS WS +KD
Sbjct: 447 HCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKD 506
Query: 807 -----TPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQ 861
T + +S S + + S +S++ S + +R R KSRS S R+
Sbjct: 507 VQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKS-----GHRK 561
Query: 862 SQSRSPKRDTTRES-RRSESLSPRRETSRENKR--SQPRVKDS---------------SP 903
S+SP++ ++ S + P R T +N+ QP V ++ P
Sbjct: 562 RASKSPRKTASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKP 621
Query: 904 GEKSRSQSRERESDRDGQRRERERRTRKWSRSR-SHSRSPSRCRTKSKSSSFGRIDRDSY 962
G+K S ER + + +S + + S S + K+S + Y
Sbjct: 622 GQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKY 681
Query: 963 SPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRN---- 1018
S R PR R ++ ++ + H + P+S RN
Sbjct: 682 SDR-------SSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSD 734
Query: 1019 --DCPNWITEKINSGPDPRTRNPEKLKESHWEEN-RNENSGNSWNKNFGSGWVSNRGRGR 1075
C + S D R R +L+ S + + ++ +S K S +V R R
Sbjct: 735 HSQCSRSSSYTSISSDDGR-RAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSS 793
Query: 1076 GNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFDT 1135
R RSS Y +E S+ ++S + E+Q ++ + +
Sbjct: 794 CVRKYSESRSSLDYSSDSE-----------QSSVQATQSAQEKEKQGQMERTHNKQEKNR 842
Query: 1136 PADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSLKDQTN 1195
++S + ++TL ++ ++ R G K + E++ + K+ N
Sbjct: 843 GEEKSKSERECPHSKKRTLKENLSDHL-RNGSKPKRKNYAGSKWDSESNSERDVTKNSKN 901
Score = 45.8 bits (107), Expect = 3e-04
Identities = 77/379 (20%), Positives = 132/379 (34%), Gaps = 83/379 (21%)
Query: 739 ADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPS 798
A++K+ +S H E N S K S S SP+ R+R SR S S
Sbjct: 653 ANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSES-SPRS--------RSRSSRSRSYS 703
Query: 799 TTWSPNKDTPQEKKRPQSPSPRRETGKE-------SRKSQSPSPKNESARGRKKSRSQSP 851
+++ ++ R +SPS R + + SR S S ++ R K+ S
Sbjct: 704 RSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSG 763
Query: 852 KKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQS 911
KK+ ++ S S + R S R+ + E++ S DS +QS
Sbjct: 764 KKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYS--ESRSSLDYSSDSEQSSVQATQS 821
Query: 912 RERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRID---RDSYSPRWKG 968
+ E ++ GQ ER ++ +R S+S C K + + R+ P+ K
Sbjct: 822 AQ-EKEKQGQM-ERTHNKQEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKN 879
Query: 969 RWANDGWRCPRGNDR----YRKNDPEKQNE--------NTRKEKNDIHLDAD-------- 1008
+A W ++R KND ++ ++ E ++IH+
Sbjct: 880 -YAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTN 938
Query: 1009 ----DPNSADKH----------RNDCPNW-------------------------ITEKIN 1029
D N A K C N + EK+
Sbjct: 939 TSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLKREHTKKVKEKLK 998
Query: 1030 SGPDPRTRNPEKLKESHWE 1048
D + + P++ + HW+
Sbjct: 999 GKKDKKHKAPKRKQAFHWQ 1017
Score = 43.1 bits (100), Expect = 0.002
Identities = 91/459 (19%), Positives = 170/459 (37%), Gaps = 70/459 (15%)
Query: 805 KDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNE--SARGRKKSRSQSPKKDIARERRQS 862
KD ++K++ + S ++ S S S ++E R R++ + PK +++RR+
Sbjct: 182 KDVFEKKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKE 241
Query: 863 QSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRE---RESDRD 919
S S E R +++P+ + R + + V S+ EK + E +R
Sbjct: 242 ASSS------EEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRF 295
Query: 920 GQRRERERRT----------------RKWSRSRS----HSRSPSRCRTKSKSSSFGRIDR 959
RR+ T +K S S+S R R T +S S D
Sbjct: 296 LLRRDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDD 355
Query: 960 DSYS---PRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKH 1016
D S P WK P +++ K D ++R ++ + S
Sbjct: 356 DDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSL-----SQRSRSWS 410
Query: 1017 RNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKN---------FGSGW 1067
N + ++ +SG + R +K+K + + + K S
Sbjct: 411 YNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKS 470
Query: 1068 VSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKS 1127
+ R + +R R + SS + ++ W S+ S + SY+ KS
Sbjct: 471 STRRMKSSCDRERSSRSSSLSSHHSSKRDW-------SKSDKDVQSSLTHSSRDSYRSKS 523
Query: 1128 EQEFSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQD 1187
+ S+ + RS S SS ++ R ++ S +SG K+ ++ +
Sbjct: 524 HSQ-SYSRGSSRSRTASKSS------------SHSRSRSKSRSSSKSGHRKRASKSPRKT 570
Query: 1188 SSLKDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPM 1226
+S + N+ V L M Q + NV+ Q + A++ P+
Sbjct: 571 ASQLSE-NKPVKTEPLRATMAQNE-NVVVQPVVAENIPV 607
Score = 37.7 bits (86), Expect = 0.082
Identities = 39/172 (22%), Positives = 69/172 (40%), Gaps = 10/172 (5%)
Query: 290 AHTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDN-SGCDA 348
+++ E S + R RRK +RS + + ++S+ R+ + N G
Sbjct: 202 SNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSEEPRNKHAMNPKGHSE 261
Query: 349 PGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDE 408
++N SV SSA+ EK + + V R LL++ + A PE D
Sbjct: 262 RSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRF--LLRRDMPVVTAEPEPKIP----DV 315
Query: 409 ETAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKH 460
SD P + K + T++ H +S +C +S ++ E+ H
Sbjct: 316 APIVSDQKPSVSKSGRKIKGRG---TIRYHTPPRSRSCSESDDDDSSETPPH 364
Score = 33.9 bits (76), Expect = 1.2
Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 8/97 (8%)
Query: 334 QSQRSPISDNSGCDAPGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSS 393
+ +R + + G D+ +SN S S SS+ESE + ++ +RK RR P + + K R
Sbjct: 186 EKKRKKPTHSEGSDS--SSNSSSSSESSSESELEHERSRRRKHKRR---PKVKRSKKRRK 240
Query: 394 VAAPEKSSSNDSVDEETAESDTSPVLEKEHQPDVDSS 430
A+ + N S+ S EK VDSS
Sbjct: 241 EASSSEEPRNKHAMNPKGHSERSDTNEKR---SVDSS 274
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapiens]
Length = 1031
Score = 75.9 bits (185), Expect = 3e-13
Identities = 71/269 (26%), Positives = 118/269 (43%), Gaps = 35/269 (13%)
Query: 802 SPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARER-R 860
S ++ + R +SPS +R + R+S+S + R R++SRS+ ++ +R+R R
Sbjct: 12 SASRGRSGSRSRSRSPSDKRSKRGDDRRSRS----RDRDRRRERSRSRDKRRSRSRDRKR 67
Query: 861 QSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKS-RSQSRERESDR- 918
+SRS +RD +RE RRS S RR SR R R + SSPG KS ++++R R ++
Sbjct: 68 LRRSRSRERDRSRERRRSRSRDRRRSRSRSRGR---RSRSSSPGNKSKKTENRSRSKEKT 124
Query: 919 DGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRWKGR------WAN 972
DG +E++ K + K G D++ + R W
Sbjct: 125 DGGESSKEKKKDKDDKE------------DEKEKDAGNFDQNKLEEEMRKRKERVEKWRE 172
Query: 973 DGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDCPNWITEKINSGP 1032
+ + N K + E+ + + D D DDP A+K N+ E++
Sbjct: 173 EQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEG---EEL---- 225
Query: 1033 DPRTRNPEKLKESHWEENRNENSGNSWNK 1061
DP E++KE + N G N+
Sbjct: 226 DPLDAYMEEVKEEVKKFNMRSVKGGGGNE 254
Score = 69.3 bits (168), Expect = 3e-11
Identities = 67/233 (28%), Positives = 94/233 (40%), Gaps = 51/233 (21%)
Query: 824 GKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSP 883
G+ESR + K ++RGR SRS+S R +R RS RD R RS S
Sbjct: 2 GRESRHYR----KRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDK 57
Query: 884 RRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPS 943
RR SR+ KR + +SR RE DR +RR R R+ SRSRS R
Sbjct: 58 RRSRSRDRKRLR--------------RSRSRERDRSRERRRSRSRDRRRSRSRSRGR--- 100
Query: 944 RCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDI 1003
+S+SSS G + + +R R + E+++++K
Sbjct: 101 ----RSRSSSPGN-------------------KSKKTENRSRSKEKTDGGESSKEKKK-- 135
Query: 1004 HLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSG 1056
D DD D+ D N+ K+ R EK +E + EN G
Sbjct: 136 --DKDD--KEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQ-RKKAMENIG 183
Score = 67.4 bits (163), Expect = 1e-10
Identities = 60/239 (25%), Positives = 102/239 (42%), Gaps = 45/239 (18%)
Query: 791 RSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKK-SRSQ 849
RSR SPS S D + + R + R ++ R+S+S R RK+ RS+
Sbjct: 21 RSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRS--------RDRKRLRRSR 72
Query: 850 SPKKDIARERRQSQSRSPKRDTTRE-SRRSESLSPRRETSRENKRSQPRVK----DSSPG 904
S ++D +RERR+S+SR +R +R RRS S SP ++ + RS+ + K +SS
Sbjct: 73 SRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKE 132
Query: 905 EKSRSQSRERESDRDG----------QRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSF 954
+K +E E ++D + R+R+ R KW + K +
Sbjct: 133 KKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREE----------QRKKAMENI 182
Query: 955 GRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSA 1013
G + ++ + +W+ + +D E KE N++ + DP A
Sbjct: 183 GELKKEIEEMKQGKKWSLED-----------DDDDEDDPAEAEKEGNEMEGEELDPLDA 230
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 75.5 bits (184), Expect = 4e-13
Identities = 142/828 (17%), Positives = 284/828 (34%), Gaps = 55/828 (6%)
Query: 294 EGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNSN 353
+G E + TS+T S + ++ + S S S SD+S +S+
Sbjct: 508 KGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSS 567
Query: 354 PSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEET--- 410
S S S++ S+ + + S S + + S S+DS D ++
Sbjct: 568 DSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSS 627
Query: 411 -AESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEER 469
+ESD+S + + + D SN + ++ ++ + ++ + S+ ++ ++
Sbjct: 628 KSESDSS---DSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSS 684
Query: 470 VGSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQI 529
S SS+S + + ++ ++ +S S N D D
Sbjct: 685 NSSDSSDS---------SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDS- 734
Query: 530 SGLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSL 589
S S S +D +D S + S SD S++ S + + S
Sbjct: 735 SDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDS 794
Query: 590 VEITEHKDFTLKTEELIESPKLESSEGEIIQTVD--RQSVKSPEVQLLGHVETEDVEIIA 647
+ + D + ++ S +SS+ + + D S S ++ D +
Sbjct: 795 SDSSNSSDSSNSSDS---SDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGS 851
Query: 648 TCDTFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQK 707
D+ D +N DS ++ ++ N+ + NES S + +
Sbjct: 852 DSDSSNRSDSSNSSDSSDS---SDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDS 908
Query: 708 HFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKV 767
S D+++ S SD +ES ++NS + S N+ SSD +D
Sbjct: 909 SNSSDSSD------SSNSSDSSESS----------NSSDNSNSSDSSNSSDSSDSSDSSN 952
Query: 768 ETVSQPSESPKDTIDKTKKPRTRRS-RFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKE 826
+ S S ++ D + + S +S ++ S + + + S ++
Sbjct: 953 SSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1012
Query: 827 SRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRE 886
S S S N S S S + + S S +++ S S+S
Sbjct: 1013 SDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1072
Query: 887 TSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCR 946
+ + DSS S S +S + + S S S S
Sbjct: 1073 SDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1132
Query: 947 TKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLD 1006
+ S SS DS ++ + + + N + + +D
Sbjct: 1133 SDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1192
Query: 1007 ADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSG 1066
+D +S+D + + ++ +S + + +S+ + +++S +S + N
Sbjct: 1193 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDS 1252
Query: 1067 WVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSES 1114
S+ SS + D N+ K +GN+N S S+S
Sbjct: 1253 SDSS-------------DSSDSTSDSNDESDSQSKSGNGNNNGSDSDS 1287
Score = 73.2 bits (178), Expect = 2e-12
Identities = 104/551 (18%), Positives = 205/551 (37%), Gaps = 12/551 (2%)
Query: 653 GNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFSED 712
GN+D N+ +S+NN + ++S + N S ++ + T S
Sbjct: 473 GNDDANS--ESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDST--SDTNNSDSNG 528
Query: 713 NNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQ 772
N + D S + +S+ S ++D +++S + S+++ +S + ++ S
Sbjct: 529 NGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSS 588
Query: 773 PSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQS 832
S S D+ D + + S S S+ S + D+ + + +S S ++ +S S S
Sbjct: 589 DS-SDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNS 647
Query: 833 PSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENK 892
+ S + S S + + S S S +++ S S+S S E+S +
Sbjct: 648 SDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDS-SNSSESSDSSD 706
Query: 893 RSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSS 952
S DSS S S + + D + S S + S S + + S
Sbjct: 707 SSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSD 766
Query: 953 SFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNS 1012
S D S +ND +D +D ++++ + D+D NS
Sbjct: 767 SSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSS---DSDSSNS 823
Query: 1013 ADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEE--NRNENSGNSWNKNFGSGWVSN 1070
+D + + + +S + + S+ + N +++S +S + N S+
Sbjct: 824 SDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSS 883
Query: 1071 RGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQE 1130
N + S+ + D +++ + S NS+ S S S + +
Sbjct: 884 DSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSD 943
Query: 1131 FSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSL 1190
S + + S +S SS + + +D + S NSS S + + DSS
Sbjct: 944 SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSS-DSSDSSDSSDSSDSSDSSN 1002
Query: 1191 KDQTNQQVDGS 1201
++ D S
Sbjct: 1003 SSDSSDSSDSS 1013
Score = 71.2 bits (173), Expect = 7e-12
Identities = 108/565 (19%), Positives = 192/565 (33%), Gaps = 27/565 (4%)
Query: 650 DTFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHF 709
D+ D NN DS N N N K + + + S ++ S+ +
Sbjct: 514 DSDSTSDTNN-SDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSN--SSDSSDSSDSD 570
Query: 710 SEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKV-- 767
S D+N DS SD + S+ S ++D +++S + S ++ SSD +D K
Sbjct: 571 SSDSNS----SSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDS 626
Query: 768 ---ETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETG 824
E+ S S+S D+ D + S S + + + + S S
Sbjct: 627 SKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNS 686
Query: 825 KESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPR 884
+S S S +ES+ S S S + S S S + +S S S
Sbjct: 687 SDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDS 746
Query: 885 RETSRENKRSQPR-------VKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRS 937
++S + S DSS S S +S+ + + S S
Sbjct: 747 SDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNS 806
Query: 938 HSRSPSRCRTKSKSSSFGRIDRDS-YSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENT 996
S S + S SS+ S S ++D G+D N + N +
Sbjct: 807 SDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSD 866
Query: 997 RKEKNDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSG 1056
+ +D +D +S+D + + + ++ NS + + S + + +
Sbjct: 867 SSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSES 926
Query: 1057 NSWNKNFGSGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFK 1116
++ + N S SN + S D + + + S +S+SS S
Sbjct: 927 SNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNS---- 982
Query: 1117 FVEQQSYKRKSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGW 1176
S + S + + S +S SS + + +D N + S S
Sbjct: 983 ---SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDS 1039
Query: 1177 MKQEEETSGQDSSLKDQTNQQVDGS 1201
+ + DSS ++ D S
Sbjct: 1040 SDSSDSSDSSDSSDSSNSSDSSDSS 1064
Score = 70.9 bits (172), Expect = 9e-12
Identities = 129/734 (17%), Positives = 251/734 (34%), Gaps = 43/734 (5%)
Query: 290 AHTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAET-ASQSQRSPISDNS-GCD 347
+++ + + +S +S++ S + ++ + + ++ +++ +S S S SDNS D
Sbjct: 599 SNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSD 658
Query: 348 APGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVD 407
+ +SN S S SS S+ + S S + E S S+DS D
Sbjct: 659 SSNSSNSSDSSDSSDSSDSSSSSDSSNSSD---------SSDSSDSSNSSESSDSSDSSD 709
Query: 408 EETAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTE 467
++++S S + D DSSN S++ S N ++N
Sbjct: 710 SDSSDSSDS---SNSNSSDSDSSN-----------SSDSSDSSNSSDSSDSSDSSNSSDS 755
Query: 468 ERVGSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQD 527
SS+ S + D + + ++N S+ S++
Sbjct: 756 SDSSDSSNSSDSSD-----SSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSS 810
Query: 528 QISGLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITES 587
S S S+ + + + + +S+S S S N N ++S
Sbjct: 811 DSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDS 870
Query: 588 SLVEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIA 647
S + + D + ++ S +SS+ D + ++ E
Sbjct: 871 S--DSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSN 928
Query: 648 TCDTFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQK 707
+ D + D +N DS ++ +N ++ ++S + + +
Sbjct: 929 SSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDS 988
Query: 708 HFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKV 767
S D+++ S SD ++S + S ++D +++S + S ++ SSD +D
Sbjct: 989 SDSSDSSDSSDSSNSSDSSDSSDSS-DSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSD 1047
Query: 768 ETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQS-----PSPRRE 822
+ S S + D+ D + + S S S+ S + D+ S S +
Sbjct: 1048 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSD 1107
Query: 823 TGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLS 882
+ S S S N S S S + + S S D++ S S+S
Sbjct: 1108 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSD 1167
Query: 883 PRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSP 942
+ + + DSS S S +S + + S S S
Sbjct: 1168 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1227
Query: 943 SRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKND 1002
S +S SS DS + ++ ND + + Q+++ N
Sbjct: 1228 SSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSND-----ESDSQSKSGNGNNNG 1282
Query: 1003 IHLDADDPNSADKH 1016
D+D S H
Sbjct: 1283 SDSDSDSEGSDSNH 1296
Score = 68.6 bits (166), Expect = 4e-11
Identities = 92/497 (18%), Positives = 169/497 (34%), Gaps = 30/497 (6%)
Query: 710 SEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVET 769
S+ ++ E DS SD ++S+ S ++D +++S + S N+ SSD +D +
Sbjct: 620 SDSKSDSSKSESDSSDSD-SKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSS 678
Query: 770 VSQPSESPKDTIDKTKKPRTRRSR-----FHSPSTTWSPNKDTPQEKKRPQSPSPRRETG 824
S S + D+ D + + S S S+ S + ++ + S ++
Sbjct: 679 SSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSS 738
Query: 825 KESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPR 884
S S S N S S S + + S S D+ S S+S
Sbjct: 739 NSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSS 798
Query: 885 RETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSR 944
+ N DSS + S S SD + S S S S +R
Sbjct: 799 NSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNR 858
Query: 945 CRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIH 1004
+ + S S D + S +N+ +D +D + + + + +D
Sbjct: 859 SDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSS 918
Query: 1005 LDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFG 1064
+D S++ N NS + N +S N +++S +S + N
Sbjct: 919 NSSDSSESSNSSDNS---------NSSD---SSNSSDSSDSSDSSNSSDSSNSSDSSNSS 966
Query: 1065 SGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYK 1124
SN + S D ++ S +S++S S S
Sbjct: 967 DSSDSNSSDSSDSSNSSDSSDSSDSSDSSD---------SSDSSNSSDSS---DSSDSSD 1014
Query: 1125 RKSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETS 1184
+ + S + + S +S SS + + +D + + S S + +
Sbjct: 1015 SSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD 1074
Query: 1185 GQDSSLKDQTNQQVDGS 1201
DSS +++ D S
Sbjct: 1075 SSDSSDSSESSDSSDSS 1091
Score = 65.9 bits (159), Expect = 3e-10
Identities = 122/674 (18%), Positives = 230/674 (34%), Gaps = 68/674 (10%)
Query: 292 TQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGN 351
+ + ++S +S++ S + + S+ + + ++ S S SD+S N
Sbjct: 692 SSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSN 751
Query: 352 SNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETA 411
S+ S S+ S + + S +S + + S+S+DS D +
Sbjct: 752 SSDSSDSSDSSNSSDSSDSSDSSDS-----------SDSSNSSDSNDSSNSSDSSDSSNS 800
Query: 412 --ESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEER 469
S++S + D DSSN + N S + S + +S + D++
Sbjct: 801 SDSSNSSDSSDSSDSSDSDSSN----SSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSS 856
Query: 470 VGSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQI 529
S SS S + + N+ ++ +S S N +
Sbjct: 857 NRSDSSNS---------SDSSDSSDSSNSSDSSD--SSDSNESSNSSDSSDSSNSSDSDS 905
Query: 530 SGLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSL 589
S S S +D S SD SE+ S N S+
Sbjct: 906 SDSSNSSDSSD------------------------SSNSSDSSESSNSSDNSNSSDSSNS 941
Query: 590 VEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATC 649
+ ++ D + ++ S SS+ + D + ++ + +
Sbjct: 942 SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSN---------SSDSSDSSDSS 992
Query: 650 DTFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHF 709
D+ + D +N DS ++ ++ N S + N S + + + +
Sbjct: 993 DSSDSSDSSNSSDSSDSSDSSDSSN-----SSDSSNSSDSSNSSDSSDSSDSSDSSDSSD 1047
Query: 710 SEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVET 769
S D+++ S SD ++S + S ++D +E+S + S N+ SSD +D +
Sbjct: 1048 SSDSSDSSNSSDSSDSSDSSDSS-DSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSS 1106
Query: 770 VSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRK 829
S S D+ D + + S S S+ S + D+ + S S ++ S
Sbjct: 1107 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDS-SDSSDSSDSSDS 1165
Query: 830 SQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSR 889
S S + S S S + + S S D++ S S+S +
Sbjct: 1166 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1225
Query: 890 ENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKS 949
+ DSS S S +S + + S S+S S + + + S
Sbjct: 1226 SDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDS 1285
Query: 950 KSSSFGRIDRDSYS 963
S S G S S
Sbjct: 1286 DSDSEGSDSNHSTS 1299
Score = 65.1 bits (157), Expect = 5e-10
Identities = 108/573 (18%), Positives = 198/573 (34%), Gaps = 33/573 (5%)
Query: 650 DTFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHF 709
D+ + D ++ DS ++ ++ ++K + S E + S ++ K+
Sbjct: 597 DSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDS-------KSDSSDSNSSD 649
Query: 710 SEDNNEMIPMECDSFCSDQNESE--VEPSVNADLKQMNENSVTHCSENNMPSSDLADEKV 767
S DN++ S SD ++S + S ++D +++S + S N+ SSD +D
Sbjct: 650 SSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSD 709
Query: 768 ETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSP--SPRRETGK 825
S S+S + + S S S+ S + D+ S S ++
Sbjct: 710 SDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSD 769
Query: 826 ESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRE--SRRSESLSP 883
S S S N S + S S + + S S D++ S S+S +
Sbjct: 770 SSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNS 829
Query: 884 RRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPS 943
+ N DSS G S S +R S+ + S S S S
Sbjct: 830 SDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESS 889
Query: 944 RCRTKSKSSSFGRIDR-DSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKND 1002
S SS+ D DS + +N N N + N + + +D
Sbjct: 890 NSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSD 949
Query: 1003 IH--------------LDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWE 1048
D+ D NS+D + + ++ +S + + +S
Sbjct: 950 SSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1009
Query: 1049 ENRNENSGNSWNKNFGSGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSN 1108
+ +++S +S + N S SN + S D +++ N S +S+
Sbjct: 1010 SDSSDSSNSSDSSN--SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS--SNSSDSSDSSD 1065
Query: 1109 SSGSESFKFVEQQSYKRKSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRN 1168
SS S S +S +D S +S SS + + +D + +
Sbjct: 1066 SSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSD-SSDSSDSSDSSDSSDSSDSSDSSNSS 1124
Query: 1169 SSGPQSGWMKQEEETSGQDSSLKDQTNQQVDGS 1201
S S + ++ DSS +++ D S
Sbjct: 1125 DSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSS 1157
Score = 49.3 bits (116), Expect = 3e-05
Identities = 94/522 (18%), Positives = 183/522 (35%), Gaps = 72/522 (13%)
Query: 710 SEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCS--------ENNMPSSD 761
+++ +E+I C + + N SE+ P +N+ E VT + + PS +
Sbjct: 193 TDNEDEIIENSCRN---EGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGN 249
Query: 762 LADEKVETVSQPSESPK--DTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSP 819
ADE + S E + + D + + + + H + + K P
Sbjct: 250 GADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPE- 308
Query: 820 RRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSE 879
GKE P NE G K S+S+ I + + ++ RES+R E
Sbjct: 309 ----GKED-------PHNE-VDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVE 356
Query: 880 S-LSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSH 938
+ ++ ET K ++ P +R+ ++E +G+ + + H
Sbjct: 357 NRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQ-----------H 405
Query: 939 SRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNEN--T 996
+ K++ G + GN N N +
Sbjct: 406 GMILGKGNVKTQGEVVNI--------------EGPGQKSEPGNKVGHSNTGSDSNSDGYD 451
Query: 997 RKEKNDIHLDADDPNSADKHR-NDCPNWITEKINSGPDPRTRNPEKLKE----------- 1044
+ +D + DDPNS+D+ ND N ++ +S + N ++ K+
Sbjct: 452 SYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAE 511
Query: 1045 -----SHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQN 1099
S + N ++++GN N N + S+ G+G+ + S D +++ +
Sbjct: 512 DDDSDSTSDTNNSDSNGNGNNGNDDND-KSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSD 570
Query: 1100 RKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQ 1159
+ +S+S S+S S S +D S + +S + K+ + +
Sbjct: 571 SSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSE 630
Query: 1160 NYYSRRGRNSSGPQSGWMKQEEETSGQDSSLKDQTNQQVDGS 1201
+ S S S + + DSS ++ D S
Sbjct: 631 SDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSS 672
Score = 32.7 bits (73), Expect = 2.6
Identities = 28/177 (15%), Positives = 70/177 (39%), Gaps = 2/177 (1%)
Query: 292 TQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGN 351
+ + + +S +SN+ S + + S + ++++ S S SD+S +
Sbjct: 1126 SSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1185
Query: 352 SNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETA 411
S+ S S++S + + S S + + + S+DS D +
Sbjct: 1186 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD--SSDSSDSSDSSDSNESSDSSDSSDS 1243
Query: 412 ESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEE 468
++ + DS++ ++ +++S N + ++ +SE +N+ T +
Sbjct: 1244 SDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSD 1300
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 75.5 bits (184), Expect = 4e-13
Identities = 74/292 (25%), Positives = 126/292 (43%), Gaps = 47/292 (16%)
Query: 733 VEPSVNA-DLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPK---DTIDKTKKPR 788
++P++ A L N NS + ++ + D K+ V+ SP DT K +
Sbjct: 163 LDPALAALGLPGANLNSQSLAADQLLKLMSTVDPKLNHVAAGLVSPSLKSDTSSKEIEEA 222
Query: 789 TRRSRFHSPSTTWSPNKDTPQEKKR---PQSPSPRRETGKESR--KSQSPSPKNESARGR 843
+R R + + D +EK+R +S S RR T SR +S+S S + ++ R
Sbjct: 223 MKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSR 282
Query: 844 KKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSP 903
+ RS+SP++ RS R+ R SR + +++ +E KRS+ K S
Sbjct: 283 SRRRSKSPRR----------RRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYST 332
Query: 904 GEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYS 963
+SRS SRER R RR+R +RS RSP R ++S S + ++
Sbjct: 333 ARRSRSASRER----------RRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEK---- 378
Query: 964 PRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADK 1015
+ D+ R D +++ + +K+ D D + + +DK
Sbjct: 379 --------------KKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDK 416
Score = 68.2 bits (165), Expect = 6e-11
Identities = 60/214 (28%), Positives = 93/214 (43%), Gaps = 16/214 (7%)
Query: 759 SSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKK--RPQS 816
SS +E ++ V + I+ KK RR HS S + S + TP + R +S
Sbjct: 215 SSKEIEEAMKRVREAQSLISAAIEPDKKEEKRR---HSRSRSRSRRRRTPSSSRHRRSRS 271
Query: 817 PSPRRETGKESRKSQSPSPKNESARGR---KKSRSQSPKKDIARERRQSQSRS--PKRDT 871
S RR K + +S SP+ + R ++SRS S +D +E ++ + PK +
Sbjct: 272 RSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYS 331
Query: 872 TRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQS-----RERESDRDGQRRERE 926
T RS S RR SR RS P+ S + SRS S +E++ D+D +R E
Sbjct: 332 TARRSRSASRERRRRRSRSGTRS-PKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDE 390
Query: 927 RRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRD 960
R + +S + R R ++ RD
Sbjct: 391 RERSTSKKKKSKDKEKDRERKSESDKDVKQVTRD 424
Score = 60.8 bits (146), Expect = 9e-09
Identities = 60/202 (29%), Positives = 91/202 (45%), Gaps = 22/202 (10%)
Query: 733 VEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRS 792
+EP + K+ + S + PSS + S S + ++K PR RRS
Sbjct: 237 IEPDKKEE-KRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRS 295
Query: 793 -------RFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKK 845
R S S T K+ +EKKR ++P T + SR S E R R +
Sbjct: 296 HSRERGRRSRSTSKTRDKKKED-KEKKRSKTPPKSYSTARRSR-----SASRERRRRRSR 349
Query: 846 SRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSR-ENKRSQPRVKDSSPG 904
S ++SPKK R ++ SRSP + R ++ + +E SR E +RS + K S
Sbjct: 350 SGTRSPKKP--RSPKRKLSRSP---SPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDK 404
Query: 905 EKSRSQSRERESDRDGQRRERE 926
EK R R+ ESD+D ++ R+
Sbjct: 405 EKDR--ERKSESDKDVKQVTRD 424
Score = 50.8 bits (120), Expect = 9e-06
Identities = 49/187 (26%), Positives = 78/187 (41%), Gaps = 15/187 (8%)
Query: 887 TSRENKRSQPRVKDS-SPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRC 945
+S+E + + RV+++ S + ++ E R + R R RR R S SR H RS R
Sbjct: 215 SSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSR-HRRS--RS 271
Query: 946 RTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHL 1005
R++ +S S R R S SPR + + + R R + R E + + K +
Sbjct: 272 RSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYS 331
Query: 1006 DADDPNSADKHRN-----------DCPNWITEKINSGPDPRTRNPEKLKESHWEENRNEN 1054
A SA + R P K++ P PR EK K+ E +R+E
Sbjct: 332 TARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDER 391
Query: 1055 SGNSWNK 1061
++ K
Sbjct: 392 ERSTSKK 398
Score = 39.3 bits (90), Expect = 0.028
Identities = 46/207 (22%), Positives = 85/207 (41%), Gaps = 15/207 (7%)
Query: 296 EEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQ-----RSPISDNSGCDAPG 350
+E+K+ S +R RR+ ++ RRS +R + S+S+ +SP S G
Sbjct: 242 KEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERG 301
Query: 351 NSNPSLSVPSSAESE----KQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSV 406
+ S S + E K+++ PK S R + +++ R S + S
Sbjct: 302 RRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSP 361
Query: 407 DEETAESDTSPVLEKEHQPDVDS--SNICTVQTHVENQSANCLKSCNEQIEESEKH---- 460
+ + S + +KE + D D S ++ + + + + E+ ES+K
Sbjct: 362 KRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQV 421
Query: 461 TANYDTEERVGSSSSESCAQDLPVLVG 487
T +YD EE+ S E + P+ G
Sbjct: 422 TRDYDEEEQGYDSEKEKKEEKKPIETG 448
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 75.1 bits (183), Expect = 5e-13
Identities = 56/216 (25%), Positives = 99/216 (45%), Gaps = 17/216 (7%)
Query: 809 QEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPK 868
+EK+R + RRE +E R+ + + E R R++ R + +++ RER + + R+ +
Sbjct: 298 KEKERQEIEKERRERERE-RERERERREREREREREREREKEKERERERERDRDRDRTKE 356
Query: 869 RDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERR 928
RD R+ R R + R RS+ R K S E+ R + RERE +R+ +R R
Sbjct: 357 RDRDRDRERDRDRDRERSSDRNKDRSRSREK-SRDRERERERERERERERERERERERER 415
Query: 929 TRKWSRSRSHSRSPSRCRTKSKSSSFGR--IDRD------SYSPRWKGRWANDGWRCPRG 980
R+ R R + R R + + ++ R ++R +Y R K W + R
Sbjct: 416 EREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLK-NWEIRERKKTRE 474
Query: 981 NDRYRKNDPEKQNENTRKEK------NDIHLDADDP 1010
++ + + E++ E ++ K D D DDP
Sbjct: 475 YEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDP 510
Score = 63.2 bits (152), Expect = 2e-09
Identities = 49/185 (26%), Positives = 83/185 (44%), Gaps = 24/185 (12%)
Query: 825 KESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPR 884
+E K + K E +G+K+ Q +I +ERR+ + + RE R
Sbjct: 279 REISKFRDTHKKLEEEKGKKEKERQ----EIEKERRERERERERERERRERERERERERE 334
Query: 885 RETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSR 944
RE +E +R + R +D + R++ R+R+ DR+ R+R+R R RS R+ R
Sbjct: 335 REKEKERERERERDRD-----RDRTKERDRDRDRE---RDRDR-----DRERSSDRNKDR 381
Query: 945 CRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIH 1004
R++ KS RD R + R R +R R+ + E++ E + +K D
Sbjct: 382 SRSREKS-------RDREREREREREREREREREREREREREREREREREREKDKKRDRE 434
Query: 1005 LDADD 1009
D +D
Sbjct: 435 EDEED 439
Score = 62.8 bits (151), Expect = 2e-09
Identities = 37/167 (22%), Positives = 76/167 (45%), Gaps = 3/167 (1%)
Query: 765 EKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETG 824
+K+E E + I+K ++ R R ++ +E+++ + RE
Sbjct: 289 KKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERD 348
Query: 825 KESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPR 884
++ +++ + R R + R +S ++ R R + +SR +R+ RE R
Sbjct: 349 RDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERE 408
Query: 885 RETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRK 931
RE RE +R + R ++ EK + + RE + + +RR+ ER+ R+
Sbjct: 409 RERERERERERERERER---EKDKKRDREEDEEDAYERRKLERKLRE 452
Score = 55.1 bits (131), Expect = 5e-07
Identities = 53/273 (19%), Positives = 106/273 (38%), Gaps = 32/273 (11%)
Query: 678 EKSLEEKNESLTEHPRSTELP-----KTHIEQIQKHFSEDNNEMIPMECDSFCSDQNESE 732
+K E+K + P + +P K I I+ ED ++I E F + E
Sbjct: 235 KKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIE--MEEDKRDLISREISKFRDTHKKLE 292
Query: 733 VEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRS 792
E +Q ++ E+ E + E ++ ++ ++ R
Sbjct: 293 EEKGKKEKERQ-----------------EIEKERRER-ERERERERERRERERERERERE 334
Query: 793 RFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPK 852
R +D +++ + + RE ++ + +S + +R R+KSR + +
Sbjct: 335 REKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERE 394
Query: 853 KDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSR 912
++ RER + + R +R+ RE R RE RE + + R +D + R R
Sbjct: 395 RERERERERERERERERERERERER------EREREREKDKKRDREEDEEDAYERRKLER 448
Query: 913 E-RESDRDGQRRERERRTRKWSRSRSHSRSPSR 944
+ RE + Q R + R+ ++R + + R
Sbjct: 449 KLREKEAAYQERLKNWEIRERKKTREYEKEAER 481
Score = 54.7 bits (130), Expect = 6e-07
Identities = 63/287 (21%), Positives = 112/287 (39%), Gaps = 12/287 (4%)
Query: 778 KDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQE--KKRPQSPSPRRETGKESRKSQSPSP 835
K +D+ K + + P T + +++ E K+R Q E S+ +P
Sbjct: 166 KAQLDEWKAKKKASNGNARPETVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAP 225
Query: 836 KNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRET-SRENKRS 894
ES +K + + K+DI R + T + E +R+ SRE +
Sbjct: 226 SQESDSHPRKKKKEK-KEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKF 284
Query: 895 QPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSF 954
+ K EK + + +E +++ + RERER + R R R R R K K
Sbjct: 285 RDTHKKLEE-EKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERER 343
Query: 955 GRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSAD 1014
R +RD R K R + R DR R +D K +R++ D + + +
Sbjct: 344 ER-ERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERE 402
Query: 1015 KHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNK 1061
+ R E+ R R E+ +E + +R E+ +++ +
Sbjct: 403 RERE------REREREREREREREREREREKDKKRDREEDEEDAYER 443
Score = 45.1 bits (105), Expect = 5e-04
Identities = 49/269 (18%), Positives = 104/269 (38%), Gaps = 30/269 (11%)
Query: 782 DKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESAR 841
D+ ++ + R++ S S S +D +E++R + RE +E + + + E R
Sbjct: 368 DRDRERSSDRNKDRSRSREKS--RDRERERERERERERERERERERERERERERERERER 425
Query: 842 GRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESR--------RSESLSPRRETSRENKR 893
+ K R + ++ A ERR+ + + +++ + R R ++ +E RE +R
Sbjct: 426 EKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEER 485
Query: 894 SQPRVKDSSPGEKSRSQSRERESDRDG---------QRRERERRTRKWSRSRSHSRSPSR 944
+ K++ ++ + + + DRD Q+R R+R + R R
Sbjct: 486 RREMAKEA---KRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEE 542
Query: 945 C-RTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDI 1003
+ + + G D D+ R + R K +PE + E K++ +
Sbjct: 543 LEEIRQRLLAEGHPDPDAELQRME-------QEAERRRQPQIKQEPESEEEEEEKQEKEE 595
Query: 1004 HLDADDPNSADKHRNDCPNWITEKINSGP 1032
+ + + C I+S P
Sbjct: 596 KREEPMEEEEEPEQKPCLKPTLRPISSAP 624
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sapiens]
Length = 805
Score = 75.1 bits (183), Expect = 5e-13
Identities = 115/510 (22%), Positives = 200/510 (39%), Gaps = 53/510 (10%)
Query: 577 SVVNEEKITESSLVEITEHKDFTLKTEELIESPKLESSEGEII---QTVDRQSVKSPEVQ 633
S V +E+ ++ + E + L T+ L+ L+ ++ EI + R++ K+P Q
Sbjct: 313 SPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQ 372
Query: 634 LLGHVETEDVEIIATCDTFGN---EDFNNIQDSENNLLKNNLLNTKLEKSLE-----EKN 685
L + + +G+ ED + + SE++ + L ++ + E EK
Sbjct: 373 LAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKE 432
Query: 686 ESLTEHPRSTELPKTHIEQIQKHFSE----DNNEMIPMECDSFCSD----------QNES 731
+ L H + E K E++ K +E + N + +E D + S
Sbjct: 433 QQLL-HDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTS 491
Query: 732 EVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVE-TVSQPSESPKDTIDKTKKPRTR 790
+EP K+ S + S + SS+ TVS S S +T +
Sbjct: 492 VLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSS 551
Query: 791 RSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQS 850
R S + SP + + R S + E+ + K + N ++ R++ R++S
Sbjct: 552 PKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRS 611
Query: 851 PKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQ 910
P +RERR+S+SRS R T R SR + + R N E+ R +
Sbjct: 612 P----SRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKK 667
Query: 911 SRERESDRDGQR----RERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRW 966
R R D+D ++ RERE+ RK + R + SS R+ R S R
Sbjct: 668 ERSRSIDKDRKKKDKEREREQDKRKEKQKREE-------KDFKFSSQDDRLKRKRESERT 720
Query: 967 KGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDCPNWITE 1026
R + + R + R D +K K+ H +D S+ + ++ P E
Sbjct: 721 FSRSGSISVKIIRHDSR---QDSKKSTTKDSKK----HSGSD---SSGRSSSESPGSSKE 770
Query: 1027 KINSGP-DPRTRNPEKLKESHWEENRNENS 1055
K P R+R+ EK + S + +R S
Sbjct: 771 KKAKKPKHSRSRSVEKSQRSGKKASRKHKS 800
Score = 40.4 bits (93), Expect = 0.013
Identities = 41/137 (29%), Positives = 64/137 (46%), Gaps = 22/137 (16%)
Query: 809 QEKKRPQSPSPRRETGKESRK-----SQSPSPKNESARGRKKSRSQSPKKDIAR-ERRQS 862
++K+R + R+E K K SQ K + R SRS S I R + RQ
Sbjct: 680 KDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQD 739
Query: 863 QSRSPKRDTTRESR-----RSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESD 917
+S +D+ + S RS S SP +S+E K +P+ SRS+S E+ S
Sbjct: 740 SKKSTTKDSKKHSGSDSSGRSSSESPG--SSKEKKAKKPK--------HSRSRSVEK-SQ 788
Query: 918 RDGQRRERERRTRKWSR 934
R G++ R+ +++ SR
Sbjct: 789 RSGKKASRKHKSKSRSR 805
Score = 36.6 bits (83), Expect = 0.18
Identities = 35/146 (23%), Positives = 60/146 (41%), Gaps = 4/146 (2%)
Query: 771 SQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKK-RPQSPSPRRETGKESRK 829
++ E K+ K R ++ + K +EK + S R + +ES +
Sbjct: 660 AKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESER 719
Query: 830 SQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRE---SRRSESLSPRRE 886
+ S S R SR S K ++ S S S R ++ S+ ++ P+
Sbjct: 720 TFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHS 779
Query: 887 TSRENKRSQPRVKDSSPGEKSRSQSR 912
SR ++SQ K +S KS+S+SR
Sbjct: 780 RSRSVEKSQRSGKKASRKHKSKSRSR 805
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sapiens]
Length = 805
Score = 75.1 bits (183), Expect = 5e-13
Identities = 115/510 (22%), Positives = 200/510 (39%), Gaps = 53/510 (10%)
Query: 577 SVVNEEKITESSLVEITEHKDFTLKTEELIESPKLESSEGEII---QTVDRQSVKSPEVQ 633
S V +E+ ++ + E + L T+ L+ L+ ++ EI + R++ K+P Q
Sbjct: 313 SPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQ 372
Query: 634 LLGHVETEDVEIIATCDTFGN---EDFNNIQDSENNLLKNNLLNTKLEKSLE-----EKN 685
L + + +G+ ED + + SE++ + L ++ + E EK
Sbjct: 373 LAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKE 432
Query: 686 ESLTEHPRSTELPKTHIEQIQKHFSE----DNNEMIPMECDSFCSD----------QNES 731
+ L H + E K E++ K +E + N + +E D + S
Sbjct: 433 QQLL-HDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTS 491
Query: 732 EVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVE-TVSQPSESPKDTIDKTKKPRTR 790
+EP K+ S + S + SS+ TVS S S +T +
Sbjct: 492 VLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSS 551
Query: 791 RSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQS 850
R S + SP + + R S + E+ + K + N ++ R++ R++S
Sbjct: 552 PKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRS 611
Query: 851 PKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQ 910
P +RERR+S+SRS R T R SR + + R N E+ R +
Sbjct: 612 P----SRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKK 667
Query: 911 SRERESDRDGQR----RERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRW 966
R R D+D ++ RERE+ RK + R + SS R+ R S R
Sbjct: 668 ERSRSIDKDRKKKDKEREREQDKRKEKQKREE-------KDFKFSSQDDRLKRKRESERT 720
Query: 967 KGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDCPNWITE 1026
R + + R + R D +K K+ H +D S+ + ++ P E
Sbjct: 721 FSRSGSISVKIIRHDSR---QDSKKSTTKDSKK----HSGSD---SSGRSSSESPGSSKE 770
Query: 1027 KINSGP-DPRTRNPEKLKESHWEENRNENS 1055
K P R+R+ EK + S + +R S
Sbjct: 771 KKAKKPKHSRSRSVEKSQRSGKKASRKHKS 800
Score = 40.4 bits (93), Expect = 0.013
Identities = 41/137 (29%), Positives = 64/137 (46%), Gaps = 22/137 (16%)
Query: 809 QEKKRPQSPSPRRETGKESRK-----SQSPSPKNESARGRKKSRSQSPKKDIAR-ERRQS 862
++K+R + R+E K K SQ K + R SRS S I R + RQ
Sbjct: 680 KDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQD 739
Query: 863 QSRSPKRDTTRESR-----RSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESD 917
+S +D+ + S RS S SP +S+E K +P+ SRS+S E+ S
Sbjct: 740 SKKSTTKDSKKHSGSDSSGRSSSESPG--SSKEKKAKKPK--------HSRSRSVEK-SQ 788
Query: 918 RDGQRRERERRTRKWSR 934
R G++ R+ +++ SR
Sbjct: 789 RSGKKASRKHKSKSRSR 805
Score = 36.6 bits (83), Expect = 0.18
Identities = 35/146 (23%), Positives = 60/146 (41%), Gaps = 4/146 (2%)
Query: 771 SQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKK-RPQSPSPRRETGKESRK 829
++ E K+ K R ++ + K +EK + S R + +ES +
Sbjct: 660 AKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESER 719
Query: 830 SQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRE---SRRSESLSPRRE 886
+ S S R SR S K ++ S S S R ++ S+ ++ P+
Sbjct: 720 TFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHS 779
Query: 887 TSRENKRSQPRVKDSSPGEKSRSQSR 912
SR ++SQ K +S KS+S+SR
Sbjct: 780 RSRSVEKSQRSGKKASRKHKSKSRSR 805
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 73.6 bits (179), Expect = 1e-12
Identities = 58/186 (31%), Positives = 87/186 (46%), Gaps = 14/186 (7%)
Query: 778 KDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKN 837
K T+++ K+ R R P K+ + ++R + RE + R+ + +
Sbjct: 224 KATVEELKEKL--RKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREK 281
Query: 838 ESARGR---KKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETS------ 888
E AR R K+SRS+S +RR S+SR KR +RE RRS S RR S
Sbjct: 282 ERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSER 341
Query: 889 RENKRSQPRVKDSSPGEKS---RSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRC 945
+ RS+ R + S KS RS+SR+RE DR + +E+ K S +S SR
Sbjct: 342 KHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSE 401
Query: 946 RTKSKS 951
T ++S
Sbjct: 402 DTNTES 407
Score = 70.1 bits (170), Expect = 1e-11
Identities = 49/205 (23%), Positives = 96/205 (46%), Gaps = 11/205 (5%)
Query: 809 QEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPK 868
+EK R ++ P R+ + K + + E R R++ + +++ RE+ +++ R +
Sbjct: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERR 290
Query: 869 RDTTRESRRSESLSPRR-ETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERER 927
+ + SR S S RR SR++KRS+ R + +SRS+ R R D R+
Sbjct: 291 KRSRSRSRHSSRTSDRRCSRSRDHKRSRSRER-----RRSRSRDRRRSRSHDRSERKHRS 345
Query: 928 RTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKN 987
R+R RS+S R + R+KS+ ++D S + R ++D + R +++
Sbjct: 346 RSRDRRRSKSRDRKSYKHRSKSRDR-----EQDRKSKEKEKRGSDDKKSSVKSGSREKQS 400
Query: 988 DPEKQNENTRKEKNDIHLDADDPNS 1012
+ KN+++ ++D S
Sbjct: 401 EDTNTESKESDTKNEVNGTSEDIKS 425
Score = 48.5 bits (114), Expect = 5e-05
Identities = 44/159 (27%), Positives = 72/159 (45%), Gaps = 20/159 (12%)
Query: 772 QPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQ 831
+ E K+ ++ + RSR S T ++ KR +S RR ++ R+S+
Sbjct: 275 EEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSR 334
Query: 832 SPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSREN 891
S R +K RS+S R+RR+S+SR R+S + S S RE R++
Sbjct: 335 SHD------RSERKHRSRS------RDRRRSKSRD------RKSYKHRSKSRDREQDRKS 376
Query: 892 KRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTR 930
K + R D +S SRE++S+ D +E T+
Sbjct: 377 KEKEKRGSDDKK-SSVKSGSREKQSE-DTNTESKESDTK 413
Score = 47.4 bits (111), Expect = 1e-04
Identities = 50/203 (24%), Positives = 75/203 (36%), Gaps = 24/203 (11%)
Query: 869 RDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERR 928
R T E R E L ++ E ++ + R ++ E+ R + RE E + R+RERR
Sbjct: 235 RKRTEEPDRDERLKKEKQEREEREKERERERE----ERERKRRREEEEREKERARDRERR 290
Query: 929 TRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKND 988
R SRS SR +++ R RD R + R R R DR R
Sbjct: 291 KR--------SRSRSRHSSRTSDRRCSR-SRDHKRSRSRER------RRSRSRDRRRSRS 335
Query: 989 PEKQNENTRKEKNDIHLDADDPNSADKHRN-----DCPNWITEKINSGPDPRTRNPEKLK 1043
++ R D + KHR+ + EK G D + + +
Sbjct: 336 HDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGS 395
Query: 1044 ESHWEENRNENSGNSWNKNFGSG 1066
E+ N S S KN +G
Sbjct: 396 REKQSEDTNTESKESDTKNEVNG 418
Score = 45.8 bits (107), Expect = 3e-04
Identities = 70/322 (21%), Positives = 135/322 (41%), Gaps = 31/322 (9%)
Query: 580 NEEKITESSLVEITEHKDFTLKT-EELIESPKLESSEG--EIIQTV--DRQSVKSPEVQL 634
NEEKI +T+ D L+ EEL K+E ++G ++++ + +R+ ++S +
Sbjct: 125 NEEKIQV-----LTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTI 179
Query: 635 LGHVETE-DVEIIATCDTFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESL---TE 690
E +E+ C F + ++ + K ++ K++ ++EE E L TE
Sbjct: 180 ESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTE 239
Query: 691 HPRSTELPKTHIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVT 750
P E K ++ ++ E E E ++ E E E + + + ++ + +
Sbjct: 240 EPDRDERLKKEKQEREEREKEREREREERERKRR-REEEEREKERARDRERRKRSRSRSR 298
Query: 751 HCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQE 810
H SS +D + S +++ RRSR H S K +
Sbjct: 299 H-------SSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDR----SERKHRSRS 347
Query: 811 KKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRD 870
+ R +S S R++ K KS+ ++ ++ ++K S K + R+ QS D
Sbjct: 348 RDRRRSKSRDRKSYKHRSKSRD-REQDRKSKEKEKRGSDDKKSSVKSGSREKQS----ED 402
Query: 871 TTRESRRSESLSPRRETSRENK 892
T ES+ S++ + TS + K
Sbjct: 403 TNTESKESDTKNEVNGTSEDIK 424
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 73.6 bits (179), Expect = 1e-12
Identities = 58/186 (31%), Positives = 87/186 (46%), Gaps = 14/186 (7%)
Query: 778 KDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKN 837
K T+++ K+ R R P K+ + ++R + RE + R+ + +
Sbjct: 224 KATVEELKEKL--RKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREK 281
Query: 838 ESARGR---KKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETS------ 888
E AR R K+SRS+S +RR S+SR KR +RE RRS S RR S
Sbjct: 282 ERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSER 341
Query: 889 RENKRSQPRVKDSSPGEKS---RSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRC 945
+ RS+ R + S KS RS+SR+RE DR + +E+ K S +S SR
Sbjct: 342 KHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSE 401
Query: 946 RTKSKS 951
T ++S
Sbjct: 402 DTNTES 407
Score = 70.1 bits (170), Expect = 1e-11
Identities = 49/205 (23%), Positives = 96/205 (46%), Gaps = 11/205 (5%)
Query: 809 QEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPK 868
+EK R ++ P R+ + K + + E R R++ + +++ RE+ +++ R +
Sbjct: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERR 290
Query: 869 RDTTRESRRSESLSPRR-ETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERER 927
+ + SR S S RR SR++KRS+ R + +SRS+ R R D R+
Sbjct: 291 KRSRSRSRHSSRTSDRRCSRSRDHKRSRSRER-----RRSRSRDRRRSRSHDRSERKHRS 345
Query: 928 RTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKN 987
R+R RS+S R + R+KS+ ++D S + R ++D + R +++
Sbjct: 346 RSRDRRRSKSRDRKSYKHRSKSRDR-----EQDRKSKEKEKRGSDDKKSSVKSGSREKQS 400
Query: 988 DPEKQNENTRKEKNDIHLDADDPNS 1012
+ KN+++ ++D S
Sbjct: 401 EDTNTESKESDTKNEVNGTSEDIKS 425
Score = 48.5 bits (114), Expect = 5e-05
Identities = 44/159 (27%), Positives = 72/159 (45%), Gaps = 20/159 (12%)
Query: 772 QPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQ 831
+ E K+ ++ + RSR S T ++ KR +S RR ++ R+S+
Sbjct: 275 EEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSR 334
Query: 832 SPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSREN 891
S R +K RS+S R+RR+S+SR R+S + S S RE R++
Sbjct: 335 SHD------RSERKHRSRS------RDRRRSKSRD------RKSYKHRSKSRDREQDRKS 376
Query: 892 KRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTR 930
K + R D +S SRE++S+ D +E T+
Sbjct: 377 KEKEKRGSDDKK-SSVKSGSREKQSE-DTNTESKESDTK 413
Score = 47.4 bits (111), Expect = 1e-04
Identities = 50/203 (24%), Positives = 75/203 (36%), Gaps = 24/203 (11%)
Query: 869 RDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERR 928
R T E R E L ++ E ++ + R ++ E+ R + RE E + R+RERR
Sbjct: 235 RKRTEEPDRDERLKKEKQEREEREKERERERE----ERERKRRREEEEREKERARDRERR 290
Query: 929 TRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKND 988
R SRS SR +++ R RD R + R R R DR R
Sbjct: 291 KR--------SRSRSRHSSRTSDRRCSR-SRDHKRSRSRER------RRSRSRDRRRSRS 335
Query: 989 PEKQNENTRKEKNDIHLDADDPNSADKHRN-----DCPNWITEKINSGPDPRTRNPEKLK 1043
++ R D + KHR+ + EK G D + + +
Sbjct: 336 HDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGS 395
Query: 1044 ESHWEENRNENSGNSWNKNFGSG 1066
E+ N S S KN +G
Sbjct: 396 REKQSEDTNTESKESDTKNEVNG 418
Score = 45.8 bits (107), Expect = 3e-04
Identities = 70/322 (21%), Positives = 135/322 (41%), Gaps = 31/322 (9%)
Query: 580 NEEKITESSLVEITEHKDFTLKT-EELIESPKLESSEG--EIIQTV--DRQSVKSPEVQL 634
NEEKI +T+ D L+ EEL K+E ++G ++++ + +R+ ++S +
Sbjct: 125 NEEKIQV-----LTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTI 179
Query: 635 LGHVETE-DVEIIATCDTFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESL---TE 690
E +E+ C F + ++ + K ++ K++ ++EE E L TE
Sbjct: 180 ESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTE 239
Query: 691 HPRSTELPKTHIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVT 750
P E K ++ ++ E E E ++ E E E + + + ++ + +
Sbjct: 240 EPDRDERLKKEKQEREEREKEREREREERERKRR-REEEEREKERARDRERRKRSRSRSR 298
Query: 751 HCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQE 810
H SS +D + S +++ RRSR H S K +
Sbjct: 299 H-------SSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDR----SERKHRSRS 347
Query: 811 KKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRD 870
+ R +S S R++ K KS+ ++ ++ ++K S K + R+ QS D
Sbjct: 348 RDRRRSKSRDRKSYKHRSKSRD-REQDRKSKEKEKRGSDDKKSSVKSGSREKQS----ED 402
Query: 871 TTRESRRSESLSPRRETSRENK 892
T ES+ S++ + TS + K
Sbjct: 403 TNTESKESDTKNEVNGTSEDIK 424
>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
Length = 1007
Score = 73.2 bits (178), Expect = 2e-12
Identities = 106/445 (23%), Positives = 173/445 (38%), Gaps = 110/445 (24%)
Query: 577 SVVNEEKITESSLVEITEHKDFTLKTE---ELIESPKLESSEGEIIQTVDRQSVKSPEVQ 633
S K+ + +L+E E + +K E EL+E K++S G I+Q + S + E+
Sbjct: 93 SPAKRTKLDDLALLEDLEKQRALIKAELDNELMEG-KVQSGMGLILQGYESGSEEEGEI- 150
Query: 634 LLGHVETEDVEIIATCDTFGNEDFNNIQDSENNL-LKNNLLNTKLEKSLEEKNESLTEHP 692
H + + GN ++ L L +N + TK K + +++ T H
Sbjct: 151 ---HEKARN----------GNRSSTRSSSTKGKLELVDNKITTK--KRSKSRSKERTRHR 195
Query: 693 RSTELPKTHIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHC 752
+ K IE +++ + ++ +++ + S + L++ ++ +
Sbjct: 196 SDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQARKSKSPTLRRRSQEKI--- 252
Query: 753 SENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKD------ 806
+ P+ D K+E S+ + K I + R R + SP +KD
Sbjct: 253 GKARSPTDDKV--KIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGKSKDRRSRSK 310
Query: 807 --------TPQEKKRPQSPSPRRETGKESR------------KSQSPSPKNESARGR--- 843
T +EKK +SPS +GKE+R +S SP P+++S R R
Sbjct: 311 ERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRSPKRRSLSPKPRDKSRRSRSPL 370
Query: 844 ------KKSRSQS--------------------------------PKKDIARERRQSQSR 865
K+S+S S P+ DI R +S+
Sbjct: 371 LNDRRSKQSKSPSRTLSPGRRAKSRSLERKRREPERRRLSSPRTRPRDDILSRRERSKDA 430
Query: 866 SPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRER 925
SP + RRS SP R SR SP +SRS R S R RR+R
Sbjct: 431 SPINRWSPTRRRSR--SPIRRRSR------------SPLRRSRSPRRRSRSPR---RRDR 473
Query: 926 ERRTRKWSRSRSHSRSPSRCRTKSK 950
RR+R R RS SR R R++SK
Sbjct: 474 GRRSRSRLRRRSRSRGGRRRRSRSK 498
Score = 68.6 bits (166), Expect = 4e-11
Identities = 99/424 (23%), Positives = 168/424 (39%), Gaps = 51/424 (12%)
Query: 728 QNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQP-SESPKDTIDKTKK 786
++ SE E ++ + N +S S + +L D K+ T + S S + T ++ K
Sbjct: 141 ESGSEEEGEIHEKARNGNRSSTR--SSSTKGKLELVDNKITTKKRSKSRSKERTRHRSDK 198
Query: 787 PRTRRS-RFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKK 845
+++ TT S +K E+K+ +SPS R ++ ++RKS+SP+ + S K
Sbjct: 199 KKSKGGIEIVKEKTTRSKSK----ERKKSKSPSKRSKSQDQARKSKSPTLRRRSQEKIGK 254
Query: 846 SRSQSPKKDIARERRQSQSR--------SPKRDTTRESR-----RSESLSPR-RETSREN 891
+RS + K ++ +S+ R S RD ++SR R +S R R R++
Sbjct: 255 ARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGKSKDRRSRSKERKS 314
Query: 892 KRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKS 951
KRS+ + EK +S +++ + R RR + + RS S P +S+S
Sbjct: 315 KRSE------TDKEKKPIKSPSKDASSGKENRSPSRRPGRSPKRRSLSPKPRDKSRRSRS 368
Query: 952 SSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQN-ENTRKEKNDIHLDADDP 1010
DR S + R + G R + ++ +PE++ + R D D
Sbjct: 369 PLLN--DRRSKQSKSPSRTLSPGRRAKSRSLERKRREPERRRLSSPRTRPRD---DILSR 423
Query: 1011 NSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSN 1070
K + W + S R R+ L+ S R+ S
Sbjct: 424 RERSKDASPINRWSPTRRRSRSPIRRRSRSPLRRSRSPRRRSR---------------SP 468
Query: 1071 RGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQE 1130
R R RG R R R + R K S SE K VEQ+S + ++
Sbjct: 469 RRRDRGRRSRSRLRRRSRSRGGRRRR-SRSKVKEDKFKGSLSEGMK-VEQESSSDDNLED 526
Query: 1131 FSFD 1134
F +
Sbjct: 527 FDVE 530
Score = 54.3 bits (129), Expect = 8e-07
Identities = 47/191 (24%), Positives = 84/191 (43%), Gaps = 8/191 (4%)
Query: 770 VSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRK 829
+S P P+D I R RS+ SP WSP + + R +S SP R + R+
Sbjct: 409 LSSPRTRPRDDI----LSRRERSKDASPINRWSPTRRRSRSPIRRRSRSPLRRSRSPRRR 464
Query: 830 SQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSR 889
S+SP ++ RGR +SRS+ ++ +R R+ +SRS ++ + SE + +E+S
Sbjct: 465 SRSPRRRD---RGR-RSRSRLRRRSRSRGGRRRRSRSKVKEDKFKGSLSEGMKVEQESSS 520
Query: 890 ENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKS 949
++ V++ + +R++ + E S +S +R R+ S
Sbjct: 521 DDNLEDFDVEEEDEEALIEQRRIQRQAIVQKYKYLAEDSNMSVPSEPSSPQSSTRTRSPS 580
Query: 950 KSSSFGRIDRD 960
R+ D
Sbjct: 581 PDDILERVAAD 591
>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
Length = 1984
Score = 73.2 bits (178), Expect = 2e-12
Identities = 75/267 (28%), Positives = 105/267 (39%), Gaps = 26/267 (9%)
Query: 723 SFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSE------- 775
S CS ++ PS + N HCS L++ + + SQ S
Sbjct: 1589 SHCSPSRKNHSSPSERSWRSPSQRN---HCSPPERSCHSLSERGLHSPSQRSHRGPSQRR 1645
Query: 776 --SPKDTIDKTKKPRTRRS----RFHSPSTTW----SPNKDTPQEKKRPQSPSPRRETGK 825
SP + ++ R+ RS R SPS S ++R +SPS R G
Sbjct: 1646 HHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGP 1705
Query: 826 ESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRR 885
R+ SPS ++ + R+ RS S + + R S S +R + R S S R
Sbjct: 1706 SERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERS 1765
Query: 886 ETSRENK--RSQPRVKDSSPGEKSRSQSRERESDRDGQRRERE--RRTRKWSRSRSHSRS 941
S + RS + SP EKS ER +RR R+R RSH RS
Sbjct: 1766 HCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSH-RS 1824
Query: 942 PSRCRT-KSKSSSFGRIDRDSYSPRWK 967
PS R+ +S S RI S+SP K
Sbjct: 1825 PSERRSHRSFERSHRRISERSHSPSEK 1851
Score = 62.8 bits (151), Expect = 2e-09
Identities = 66/281 (23%), Positives = 111/281 (39%), Gaps = 19/281 (6%)
Query: 782 DKTKKPRTRRSRFHSPSTTWSPNKDTPQEK--KRPQSPSPRRETGKESRKSQSPSPKNES 839
DK F+ T P++ T + +SPS R + R+ SPS ++
Sbjct: 1532 DKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHC 1591
Query: 840 ARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPR--RETSRENKRSQPR 897
+ RK S S R +S S + + R SLS R S+ + R +
Sbjct: 1592 SPSRKNHSSPS--------ERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQ 1643
Query: 898 VKDSSPGEKSRSQSRERESDRDGQRRER--ERRTRKWSRSRSH-SRSPSRCRTKSKSSSF 954
+ SP E+S ER +RR R +R+ + RSH S S R R+ S+ S
Sbjct: 1644 RRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHR 1703
Query: 955 GRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSAD 1014
G +R +SP K + R R + P +++ ++ E+ H ++ + +
Sbjct: 1704 GPSERRHHSPS-KRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRH-HSPSERSHCSP 1761
Query: 1015 KHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENS 1055
R+ C +E+ + P R + K H R+ +S
Sbjct: 1762 SERSHCSP--SERRHRSPSERRHHSPSEKSHHSPSERSHHS 1800
Score = 50.8 bits (120), Expect = 9e-06
Identities = 62/213 (29%), Positives = 84/213 (39%), Gaps = 26/213 (12%)
Query: 773 PSE----SPKDTIDKTKKPRTRRS----RFHSPSTTWSPNKDTPQEKKRPQSPSPRRETG 824
PSE SP ++ R+ RS HSPS + +P E+ R SPS R
Sbjct: 1705 PSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSER---SHHSPSER-RHHSPSERSHCS 1760
Query: 825 KESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPR 884
R SPS + + ++ S S K + R S S +R + R SL R
Sbjct: 1761 PSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLER 1820
Query: 885 -------RETSRENKRSQPRV--KDSSPGEKSRSQSRERESDRDGQRR--ERERRTRKWS 933
R + R +RS R+ + SP EKS ER +RR +T
Sbjct: 1821 SHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSP 1880
Query: 934 RSRSHSRSPSRCR--TKSKSSSFGRIDRDSYSP 964
RSH RSPS R S+ S +R +SP
Sbjct: 1881 SERSH-RSPSGMRQGRTSERSHRSSCERTRHSP 1912
Score = 47.4 bits (111), Expect = 1e-04
Identities = 94/432 (21%), Positives = 157/432 (36%), Gaps = 68/432 (15%)
Query: 777 PKDTIDKTKKPRTRRSRFHSPSTTW-SPNKDTP----QEKKRPQSPSPRRETGKESRKSQ 831
P T+ K R++++ + + +++ S N TP Q + R SP + T K +
Sbjct: 1474 PLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDK 1533
Query: 832 SPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRES--RRSESLSPRRETSR 889
++ ++ + P + RSP + R S RR S S R S
Sbjct: 1534 LTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSP 1593
Query: 890 ENK----------RSQPRVKDSSPGEKSRSQSRERESDRDGQRRER-----------ERR 928
K RS + SP E+S ER QR R ER
Sbjct: 1594 SRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERS 1653
Query: 929 TRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKND 988
R S S S R R+ S+ S G +R SP + R + R RG R +
Sbjct: 1654 HRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPS-ERRHRSPSQRSHRGPSERRHHS 1712
Query: 989 PEKQNENT---RKEKNDIHLDADDPNSADKH-----RNDCPNWITEKINSGPDPRTR-NP 1039
P K++ + R ++ P+ H R+ P +E+ + P R+ +P
Sbjct: 1713 PSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSP---SERSHCSPSERSHCSP 1769
Query: 1040 EKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQN 1099
+ + E R+ + S + S+ R RS + +++ +
Sbjct: 1770 SERRHRSPSERRHHSP--SEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERS-----H 1822
Query: 1100 RKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQ 1159
R P S+ S S + + ++S+ S E S +P +RS + P++
Sbjct: 1823 RSPSERRSHRSFERSHRRISERSH---SPSEKSHLSPLERS-----------RCSPSE-- 1866
Query: 1160 NYYSRRGRNSSG 1171
RRG +SSG
Sbjct: 1867 ----RRGHSSSG 1874
Score = 33.9 bits (76), Expect = 1.2
Identities = 37/152 (24%), Positives = 59/152 (38%), Gaps = 12/152 (7%)
Query: 763 ADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRE 822
+ K + +Q S+SP TID P + ++ EK + ++P
Sbjct: 1197 SQRKAKIYTQASKSPTSTIDLQSGPSQSPAPVQVYIRRGQRSRPDLVEKTKTRAPGHYEF 1256
Query: 823 TG----KESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRS 878
T ES + + K R +K S S+ P K I + R+ + TT ES
Sbjct: 1257 TQVHNLPESDSESTQNEKRAKVRTKKTSDSKYPMKRITKRLRKHRKFYTNSRTTIESPSR 1316
Query: 879 ESLSPRR-------ETSRENKRSQPRVKDSSP 903
E + R +TS + + QP+ K S P
Sbjct: 1317 ELAAHLRRKRIGATQTSTASLKRQPK-KPSQP 1347
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 72.8 bits (177), Expect = 2e-12
Identities = 50/194 (25%), Positives = 86/194 (44%), Gaps = 9/194 (4%)
Query: 809 QEKKRPQSPSPRRETGKE---SRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSR 865
++++R + +ET +E R+ ++ + + R R + R + + D +ER + + R
Sbjct: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
Query: 866 SPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRER 925
+R RE+ R R+ RE KR R +D K R + R+RE+DR+ +R +
Sbjct: 63 DRQRQRERETERETERQRERQRQRERKRQTDRERD-----KDRDRERKRETDRNRERNRK 117
Query: 926 ERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYR 985
R R R R R R + + R +R + R + RWA R +
Sbjct: 118 GGRERDKQTERERDRERERQRQRERERQRQR-ERKRETDRERQRWAEREERKKERKKERK 176
Query: 986 KNDPEKQNENTRKE 999
K EK+ E R+E
Sbjct: 177 KERKEKKKEEKRRE 190
Score = 65.5 bits (158), Expect = 4e-10
Identities = 43/179 (24%), Positives = 82/179 (45%), Gaps = 8/179 (4%)
Query: 774 SESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSP 833
+E +D + + R +R ++ T +EK+R R+ ++ ++ +
Sbjct: 17 TERERDRQRERENQTERENRHRQRDRHRERDRQTDREKER------ERQKERDRQRQRER 70
Query: 834 SPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKR 893
+ E+ R R++ R + K+ RER + + R KR+T R R+ R+ E +R
Sbjct: 71 ETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERER 130
Query: 894 SQPRVKD-SSPGEKSRSQSRERESDRDGQR-RERERRTRKWSRSRSHSRSPSRCRTKSK 950
+ R + E+ R + R+RE+DR+ QR ERE R ++ + R R + K +
Sbjct: 131 DRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRR 189
Score = 62.4 bits (150), Expect = 3e-09
Identities = 46/204 (22%), Positives = 75/204 (36%), Gaps = 7/204 (3%)
Query: 858 ERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESD 917
ER++ + R R E R +T REN+ Q + R + RER+ +
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 918 RDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRC 977
RD QR+ R+ R R R R R + DRD R R +
Sbjct: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERD---KDRDRERKRETDRNRERNRKG 118
Query: 978 PRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTR 1037
R D+ + + +++ E R+ + + + D+ R W + + R
Sbjct: 119 GRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQ---RWAEREERKKERKKER 175
Query: 1038 NPEKLKESHWEENRNENSGNSWNK 1061
E+ KE EE R E+ W +
Sbjct: 176 KKER-KEKKKEEKRREDKKRKWGE 198
Score = 61.2 bits (147), Expect = 7e-09
Identities = 36/159 (22%), Positives = 76/159 (47%), Gaps = 11/159 (6%)
Query: 782 DKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESAR 841
D+ K+ ++ R ++T ++++R + +R+T +E K + K E+ R
Sbjct: 51 DREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDR 110
Query: 842 GRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDS 901
R+++R ++D ER +RD RE +R +R+ R+ + + R + +
Sbjct: 111 NRERNRKGGRERDKQTER--------ERDRERERQRQRERERQRQRERKRETDRERQRWA 162
Query: 902 SPGEKSRSQSRERESDRDGQRRERERR---TRKWSRSRS 937
E+ + + +ER+ +R +++E +RR RKW S
Sbjct: 163 EREERKKERKKERKKERKEKKKEEKRREDKKRKWGEGIS 201
Score = 43.1 bits (100), Expect = 0.002
Identities = 42/212 (19%), Positives = 84/212 (39%), Gaps = 15/212 (7%)
Query: 677 LEKSLEEKNES----LTEHPRSTELPKTH-IEQIQKHFSEDNNEMIPMECDSFCSDQNES 731
+E+ E K E+ TE R + + + E+ +H D + + D E
Sbjct: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTD------REK 54
Query: 732 EVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRR 791
E E D ++ E +E + K +T E KD D+ +K T R
Sbjct: 55 ERERQKERDRQRQRERETERETERQRERQRQRERKRQT---DRERDKDR-DRERKRETDR 110
Query: 792 SRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSP 851
+R + +K T +E+ R + +RE ++ ++ + E R ++ +
Sbjct: 111 NRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKE 170
Query: 852 KKDIARERRQSQSRSPKRDTTRESRRSESLSP 883
+K ++ R+ + + KR ++ + E +SP
Sbjct: 171 RKKERKKERKEKKKEEKRREDKKRKWGEGISP 202
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 71.2 bits (173), Expect = 7e-12
Identities = 145/671 (21%), Positives = 258/671 (38%), Gaps = 95/671 (14%)
Query: 300 QTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNSNP---SL 356
Q S +T G + + P + SQ P S AP S P
Sbjct: 941 QASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKET 1000
Query: 357 SVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAESDTS 416
P++ + E + QAP K +KPP +K +S A P+K+ +++ T
Sbjct: 1001 KAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDS-KSLTAEPQKAVLPTKLEKSPKPESTC 1059
Query: 417 PVLEKE---HQPDVDSSNICTVQTHVENQSAN-CLKSCNEQIEESEKHTA-NYDTEERVG 471
P+ + E D + N C T +NQ N C + + E ++ N T+ +
Sbjct: 1060 PLCKTELNIGSKDPPNFNTC---TECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAIS 1116
Query: 472 SSSSESCAQDLPVLVGEEGEVKKL--ENTGIEANVLCLESEISENILEKGGDPLEKQDQI 529
G+ G+++K+ +G +A+ + + +E S +K P Q ++
Sbjct: 1117 ---------------GQLGDIRKMPPAPSGPKASPMPVPTESSS---QKTAVP--PQVKL 1156
Query: 530 SGLSQSEVKTDVCTVHLP--------NDFPTCLTS-----ESKVYQPVSCPLSD---LSE 573
+ EVKT+ V L P +T+ ESK+ + + L + L E
Sbjct: 1157 VKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPE 1216
Query: 574 NVESVVNEEKITESSLVEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQ 633
+ + EEKI + E K T + ++L+ K + E E + + V+ E +
Sbjct: 1217 EKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPE-EQKHDLLKSQVQIAEEK 1275
Query: 634 LLGHVETEDVEIIATCDTFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPR 693
L G V + +Q+ + K L + +SL ++++ T+ +
Sbjct: 1276 LEGRVAPK-----------------TVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIK 1318
Query: 694 STELPKTHIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCS 753
P + Q ++ E + D+ S Q +S P +D ++ +
Sbjct: 1319 EQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKS---PQGLSDTGYSSDGISSSLG 1375
Query: 754 ENNMPSSDLADE-------KVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKD 806
E +PS DE K ++ SQ S SP D K T S + ++T + K
Sbjct: 1376 E--IPSLIPTDEKDILKGLKKDSFSQES-SPSSPSDLAKLESTVLSILEAQASTLADEKS 1432
Query: 807 TPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKK-SRSQSPKKDIARERRQSQSR 865
++K +P SP E K+ K+QS S E ++ SQ +KD ++ Q
Sbjct: 1433 --EKKTQPHEVSP--EQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIP 1488
Query: 866 SPKRDTTRESRRSESLSPRRE--------TSRENKRSQPRVKDSSPGEKSRSQSRERESD 917
S K D +S + ++ RRE + EN R + +S G S + ++ +S
Sbjct: 1489 SSK-DHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQ 1547
Query: 918 RDGQRRERERR 928
G+ + R+
Sbjct: 1548 GSGEEEDFIRK 1558
Score = 42.7 bits (99), Expect = 0.003
Identities = 49/200 (24%), Positives = 66/200 (33%), Gaps = 30/200 (15%)
Query: 1179 QEEETSGQDSSLKDQTNQQVDGSQLPINMMQPQMNVMQQQ--------------MNAQHQ 1224
QEE T Q K+Q + G P QP + +QQ + Q
Sbjct: 186 QEETTKKQKVVQKEQGKPE--GIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQ 243
Query: 1225 PMNIFPYPVGVHAPLMNIQRNPFNIHPQLPLHLHTGVPLMQ---VATPTSVSQGLPPPPP 1281
P I P G P+ + P H +LPL P + + SV LP P
Sbjct: 244 PEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSK 303
Query: 1282 PP--------PPSQQVNYIASQPDGKQLQGIPSSSHVSNNMSTPVLPAPTAAPGNT---G 1330
PP PP+QQ + SQP + PS + P PG T
Sbjct: 304 PPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363
Query: 1331 MVQGPSSGNTSSSSHSKASN 1350
GP+ + K S+
Sbjct: 364 QPLGPAKPPAQQTGSEKPSS 383
Score = 42.4 bits (98), Expect = 0.003
Identities = 113/559 (20%), Positives = 209/559 (37%), Gaps = 81/559 (14%)
Query: 313 KPAMTTPTRRSTRNTRAETASQSQRSPIS----DNSGCDAPGNSNPSLSVPSSAES-EKQ 367
KP P + T ++ + S + P S ++G + G S+ +PS + EK
Sbjct: 1328 KPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKD 1387
Query: 368 TRQAPKRKSVRRGRKP--PLLKKKLRSSVAAPEKSSSNDSVDEETAESDTSPVLEKEHQP 425
+ K+ S + P P KL S+V + ++ ++ DE++ E T P QP
Sbjct: 1388 ILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKS-EKKTQPHEVSPEQP 1446
Query: 426 DVDSSNICTVQTHVENQSANCLKSCNEQIEESE---KHTANYDTEERVGSSSS-ESCAQD 481
D ++ +E + E+I+ES+ K T D+++ + SS + ++
Sbjct: 1447 K-DQEKTQSLSETLE------ITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEF 1499
Query: 482 LPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQD-QISGLSQSEVKTD 540
+ + +E + N + + ++ D +++D Q SG + ++
Sbjct: 1500 VDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQ 1559
Query: 541 VCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLVEITEHKDFTL 600
+ + D S S+ + + L ++S + ES EE + + +H+ T
Sbjct: 1560 IIEMSADED-----ASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITA-GKHRRLTR 1613
Query: 601 KTEELIESP--KLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCDTFGNEDFN 658
K+ I+ + S E + D +SPE++ E E++ T G
Sbjct: 1614 KSSTSIDEDAGRRHSWHDEDDEAFD----ESPELKYRETKSQESEELVVT----GGGGLR 1665
Query: 659 NIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIP 718
+ E N ST K E QK S +E
Sbjct: 1666 RFKTIELN---------------------------STIADKYSAESSQKKTSLYFDEEPE 1698
Query: 719 MECDSFC-SDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESP 777
+E +S S ++ S E S S H S +S + ++ S S S
Sbjct: 1699 LEMESLTDSPEDRSRGEGS-----------SSLHASSFTPGTSPTSVSSLDEDSDSSPSH 1747
Query: 778 KDTIDKTKKPRTRRSRFHSPSTTW----SPNKDTPQEKKRPQSPSPRRETGKESRKSQSP 833
K ++K+ R R R H P S ++ +E++ + +RE ++ RKS S
Sbjct: 1748 KK--GESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSK 1805
Query: 834 SPKNESARGRKKSRSQSPK 852
K + R + R + PK
Sbjct: 1806 KSKKDKDELRAQRRRERPK 1824
Score = 35.4 bits (80), Expect = 0.41
Identities = 26/105 (24%), Positives = 48/105 (45%), Gaps = 4/105 (3%)
Query: 802 SPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQ 861
+P +PQ K + + K S + Q SPK ++A + S++ PKK ++
Sbjct: 651 APVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQP 710
Query: 862 SQSRSPKRDTTRESRRSESLS---PRRETSRENKRSQPRVKDSSP 903
+ SP ++ ++SLS P +E S +++ + V D P
Sbjct: 711 TLHGSPSA-KAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKP 754
Score = 34.3 bits (77), Expect = 0.90
Identities = 24/81 (29%), Positives = 33/81 (40%), Gaps = 4/81 (4%)
Query: 763 ADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDT-PQEKKRPQSPSPRR 821
+D K+ +S P S + K P ++ T SP D P K P P PR
Sbjct: 826 SDSKI--ISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRP 883
Query: 822 ETGKE-SRKSQSPSPKNESAR 841
G+ QSP P+ +S R
Sbjct: 884 TAGQTVPTPQQSPKPQEQSRR 904
Score = 34.3 bits (77), Expect = 0.90
Identities = 42/179 (23%), Positives = 68/179 (37%), Gaps = 28/179 (15%)
Query: 763 ADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKD-----TPQEKKRPQSP 817
AD V+ P +SPK +SP + SP K P EK P
Sbjct: 3606 ADSTVQLAPSPPKSPKV--------------LYSPISPLSPGKALESAFVPYEKPLPDDI 3651
Query: 818 SPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRR 877
SP++ + K SPK + RS S K ++ +S SR+P + T + +
Sbjct: 3652 SPQKVLHPDMAKVPPASPKT----AKMMQRSMSDPKPLSPTADES-SRAPFQYTEGYTTK 3706
Query: 878 SESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSR 936
++ KR+ P + P E+ + ++ S R R RT +R++
Sbjct: 3707 GSQTMTSSGAQKKVKRTLP----NPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAK 3761
Score = 32.3 bits (72), Expect = 3.4
Identities = 28/149 (18%), Positives = 54/149 (36%), Gaps = 11/149 (7%)
Query: 773 PSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQS 832
P++ P + T KP ++ SP+ P K Q+ + P+ + GK S +
Sbjct: 407 PAKPPTQQVG-TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTG 465
Query: 833 PSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRET----- 887
P+ G K Q P ++ ++ P + + P + +
Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG 525
Query: 888 -----SRENKRSQPRVKDSSPGEKSRSQS 911
S++ ++P + SP + S QS
Sbjct: 526 STKPPSQQPGSAKPSAQQPSPAKPSAQQS 554
Score = 32.3 bits (72), Expect = 3.4
Identities = 21/78 (26%), Positives = 32/78 (41%), Gaps = 2/78 (2%)
Query: 773 PSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQS 832
P++ P K P + P P K +PQ+ + PS ++ G +Q
Sbjct: 486 PAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS--QQPGSAKPSAQQ 543
Query: 833 PSPKNESARGRKKSRSQS 850
PSP SA+ K SQ+
Sbjct: 544 PSPAKPSAQQSTKPVSQT 561
Score = 32.0 bits (71), Expect = 4.5
Identities = 47/213 (22%), Positives = 86/213 (40%), Gaps = 23/213 (10%)
Query: 722 DSFCSDQNESEVEPSV--------NADLKQMNENSVT--HCSENNMPSS-DLADEKVETV 770
D+F S+Q PS DLK+ +++S+ SE N S+ K
Sbjct: 117 DTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPF 176
Query: 771 SQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKS 830
S+S + TKK + + P P +++P P P+++
Sbjct: 177 DLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPL-----QQQPPKPIPKQQGPGRDPLQ 231
Query: 831 QSPSPKNESARGRKKSRSQSP--KKDIARERRQSQSRSPKRDTTRESRRSESLSP---RR 885
Q +PK+ S++ +K +SQ P K I + Q+ K R++ R ++ R
Sbjct: 232 QDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRG 291
Query: 886 ETSREN--KRSQPRVKDSSPGEKSRSQSRERES 916
E+ + + S+P ++ +PG+ Q +S
Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKS 324
Score = 32.0 bits (71), Expect = 4.5
Identities = 20/94 (21%), Positives = 42/94 (44%), Gaps = 2/94 (2%)
Query: 773 PSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQS 832
PS+ P ++P + P + P++ K PQ P P + + ++ ++
Sbjct: 470 PSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKP 529
Query: 833 PSPKNESARGRKKSRSQSPKKDIARERRQSQSRS 866
PS + SA + ++ SP K A++ + S++
Sbjct: 530 PSQQPGSA--KPSAQQPSPAKPSAQQSTKPVSQT 561
Score = 31.2 bits (69), Expect = 7.7
Identities = 17/71 (23%), Positives = 32/71 (45%), Gaps = 5/71 (7%)
Query: 773 PSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQS 832
PS+ P T ++P + P +T P++ K Q PSP + + ++S K
Sbjct: 500 PSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTK--- 556
Query: 833 PSPKNESARGR 843
P +++ G+
Sbjct: 557 --PVSQTGSGK 565
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 71.2 bits (173), Expect = 7e-12
Identities = 145/671 (21%), Positives = 258/671 (38%), Gaps = 95/671 (14%)
Query: 300 QTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNSNP---SL 356
Q S +T G + + P + SQ P S AP S P
Sbjct: 941 QASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKET 1000
Query: 357 SVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAESDTS 416
P++ + E + QAP K +KPP +K +S A P+K+ +++ T
Sbjct: 1001 KAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDS-KSLTAEPQKAVLPTKLEKSPKPESTC 1059
Query: 417 PVLEKE---HQPDVDSSNICTVQTHVENQSAN-CLKSCNEQIEESEKHTA-NYDTEERVG 471
P+ + E D + N C T +NQ N C + + E ++ N T+ +
Sbjct: 1060 PLCKTELNIGSKDPPNFNTC---TECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAIS 1116
Query: 472 SSSSESCAQDLPVLVGEEGEVKKL--ENTGIEANVLCLESEISENILEKGGDPLEKQDQI 529
G+ G+++K+ +G +A+ + + +E S +K P Q ++
Sbjct: 1117 ---------------GQLGDIRKMPPAPSGPKASPMPVPTESSS---QKTAVP--PQVKL 1156
Query: 530 SGLSQSEVKTDVCTVHLP--------NDFPTCLTS-----ESKVYQPVSCPLSD---LSE 573
+ EVKT+ V L P +T+ ESK+ + + L + L E
Sbjct: 1157 VKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPE 1216
Query: 574 NVESVVNEEKITESSLVEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQ 633
+ + EEKI + E K T + ++L+ K + E E + + V+ E +
Sbjct: 1217 EKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPE-EQKHDLLKSQVQIAEEK 1275
Query: 634 LLGHVETEDVEIIATCDTFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPR 693
L G V + +Q+ + K L + +SL ++++ T+ +
Sbjct: 1276 LEGRVAPK-----------------TVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIK 1318
Query: 694 STELPKTHIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCS 753
P + Q ++ E + D+ S Q +S P +D ++ +
Sbjct: 1319 EQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKS---PQGLSDTGYSSDGISSSLG 1375
Query: 754 ENNMPSSDLADE-------KVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKD 806
E +PS DE K ++ SQ S SP D K T S + ++T + K
Sbjct: 1376 E--IPSLIPTDEKDILKGLKKDSFSQES-SPSSPSDLAKLESTVLSILEAQASTLADEKS 1432
Query: 807 TPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKK-SRSQSPKKDIARERRQSQSR 865
++K +P SP E K+ K+QS S E ++ SQ +KD ++ Q
Sbjct: 1433 --EKKTQPHEVSP--EQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIP 1488
Query: 866 SPKRDTTRESRRSESLSPRRE--------TSRENKRSQPRVKDSSPGEKSRSQSRERESD 917
S K D +S + ++ RRE + EN R + +S G S + ++ +S
Sbjct: 1489 SSK-DHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQ 1547
Query: 918 RDGQRRERERR 928
G+ + R+
Sbjct: 1548 GSGEEEDFIRK 1558
Score = 42.7 bits (99), Expect = 0.003
Identities = 49/200 (24%), Positives = 66/200 (33%), Gaps = 30/200 (15%)
Query: 1179 QEEETSGQDSSLKDQTNQQVDGSQLPINMMQPQMNVMQQQ--------------MNAQHQ 1224
QEE T Q K+Q + G P QP + +QQ + Q
Sbjct: 186 QEETTKKQKVVQKEQGKPE--GIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQ 243
Query: 1225 PMNIFPYPVGVHAPLMNIQRNPFNIHPQLPLHLHTGVPLMQ---VATPTSVSQGLPPPPP 1281
P I P G P+ + P H +LPL P + + SV LP P
Sbjct: 244 PEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSK 303
Query: 1282 PP--------PPSQQVNYIASQPDGKQLQGIPSSSHVSNNMSTPVLPAPTAAPGNT---G 1330
PP PP+QQ + SQP + PS + P PG T
Sbjct: 304 PPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363
Query: 1331 MVQGPSSGNTSSSSHSKASN 1350
GP+ + K S+
Sbjct: 364 QPLGPAKPPAQQTGSEKPSS 383
Score = 42.4 bits (98), Expect = 0.003
Identities = 113/559 (20%), Positives = 209/559 (37%), Gaps = 81/559 (14%)
Query: 313 KPAMTTPTRRSTRNTRAETASQSQRSPIS----DNSGCDAPGNSNPSLSVPSSAES-EKQ 367
KP P + T ++ + S + P S ++G + G S+ +PS + EK
Sbjct: 1328 KPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKD 1387
Query: 368 TRQAPKRKSVRRGRKP--PLLKKKLRSSVAAPEKSSSNDSVDEETAESDTSPVLEKEHQP 425
+ K+ S + P P KL S+V + ++ ++ DE++ E T P QP
Sbjct: 1388 ILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKS-EKKTQPHEVSPEQP 1446
Query: 426 DVDSSNICTVQTHVENQSANCLKSCNEQIEESE---KHTANYDTEERVGSSSS-ESCAQD 481
D ++ +E + E+I+ES+ K T D+++ + SS + ++
Sbjct: 1447 K-DQEKTQSLSETLE------ITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEF 1499
Query: 482 LPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQD-QISGLSQSEVKTD 540
+ + +E + N + + ++ D +++D Q SG + ++
Sbjct: 1500 VDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQ 1559
Query: 541 VCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLVEITEHKDFTL 600
+ + D S S+ + + L ++S + ES EE + + +H+ T
Sbjct: 1560 IIEMSADED-----ASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITA-GKHRRLTR 1613
Query: 601 KTEELIESP--KLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCDTFGNEDFN 658
K+ I+ + S E + D +SPE++ E E++ T G
Sbjct: 1614 KSSTSIDEDAGRRHSWHDEDDEAFD----ESPELKYRETKSQESEELVVT----GGGGLR 1665
Query: 659 NIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIP 718
+ E N ST K E QK S +E
Sbjct: 1666 RFKTIELN---------------------------STIADKYSAESSQKKTSLYFDEEPE 1698
Query: 719 MECDSFC-SDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESP 777
+E +S S ++ S E S S H S +S + ++ S S S
Sbjct: 1699 LEMESLTDSPEDRSRGEGS-----------SSLHASSFTPGTSPTSVSSLDEDSDSSPSH 1747
Query: 778 KDTIDKTKKPRTRRSRFHSPSTTW----SPNKDTPQEKKRPQSPSPRRETGKESRKSQSP 833
K ++K+ R R R H P S ++ +E++ + +RE ++ RKS S
Sbjct: 1748 KK--GESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSK 1805
Query: 834 SPKNESARGRKKSRSQSPK 852
K + R + R + PK
Sbjct: 1806 KSKKDKDELRAQRRRERPK 1824
Score = 35.4 bits (80), Expect = 0.41
Identities = 26/105 (24%), Positives = 48/105 (45%), Gaps = 4/105 (3%)
Query: 802 SPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQ 861
+P +PQ K + + K S + Q SPK ++A + S++ PKK ++
Sbjct: 651 APVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQP 710
Query: 862 SQSRSPKRDTTRESRRSESLS---PRRETSRENKRSQPRVKDSSP 903
+ SP ++ ++SLS P +E S +++ + V D P
Sbjct: 711 TLHGSPSA-KAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKP 754
Score = 34.3 bits (77), Expect = 0.90
Identities = 24/81 (29%), Positives = 33/81 (40%), Gaps = 4/81 (4%)
Query: 763 ADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDT-PQEKKRPQSPSPRR 821
+D K+ +S P S + K P ++ T SP D P K P P PR
Sbjct: 826 SDSKI--ISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRP 883
Query: 822 ETGKE-SRKSQSPSPKNESAR 841
G+ QSP P+ +S R
Sbjct: 884 TAGQTVPTPQQSPKPQEQSRR 904
Score = 34.3 bits (77), Expect = 0.90
Identities = 42/179 (23%), Positives = 68/179 (37%), Gaps = 28/179 (15%)
Query: 763 ADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKD-----TPQEKKRPQSP 817
AD V+ P +SPK +SP + SP K P EK P
Sbjct: 3606 ADSTVQLAPSPPKSPKV--------------LYSPISPLSPGKALESAFVPYEKPLPDDI 3651
Query: 818 SPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRR 877
SP++ + K SPK + RS S K ++ +S SR+P + T + +
Sbjct: 3652 SPQKVLHPDMAKVPPASPKT----AKMMQRSMSDPKPLSPTADES-SRAPFQYTEGYTTK 3706
Query: 878 SESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSR 936
++ KR+ P + P E+ + ++ S R R RT +R++
Sbjct: 3707 GSQTMTSSGAQKKVKRTLP----NPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAK 3761
Score = 32.3 bits (72), Expect = 3.4
Identities = 28/149 (18%), Positives = 54/149 (36%), Gaps = 11/149 (7%)
Query: 773 PSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQS 832
P++ P + T KP ++ SP+ P K Q+ + P+ + GK S +
Sbjct: 407 PAKPPTQQVG-TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTG 465
Query: 833 PSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRET----- 887
P+ G K Q P ++ ++ P + + P + +
Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG 525
Query: 888 -----SRENKRSQPRVKDSSPGEKSRSQS 911
S++ ++P + SP + S QS
Sbjct: 526 STKPPSQQPGSAKPSAQQPSPAKPSAQQS 554
Score = 32.3 bits (72), Expect = 3.4
Identities = 21/78 (26%), Positives = 32/78 (41%), Gaps = 2/78 (2%)
Query: 773 PSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQS 832
P++ P K P + P P K +PQ+ + PS ++ G +Q
Sbjct: 486 PAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS--QQPGSAKPSAQQ 543
Query: 833 PSPKNESARGRKKSRSQS 850
PSP SA+ K SQ+
Sbjct: 544 PSPAKPSAQQSTKPVSQT 561
Score = 32.0 bits (71), Expect = 4.5
Identities = 47/213 (22%), Positives = 86/213 (40%), Gaps = 23/213 (10%)
Query: 722 DSFCSDQNESEVEPSV--------NADLKQMNENSVT--HCSENNMPSS-DLADEKVETV 770
D+F S+Q PS DLK+ +++S+ SE N S+ K
Sbjct: 117 DTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPF 176
Query: 771 SQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKS 830
S+S + TKK + + P P +++P P P+++
Sbjct: 177 DLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPL-----QQQPPKPIPKQQGPGRDPLQ 231
Query: 831 QSPSPKNESARGRKKSRSQSP--KKDIARERRQSQSRSPKRDTTRESRRSESLSP---RR 885
Q +PK+ S++ +K +SQ P K I + Q+ K R++ R ++ R
Sbjct: 232 QDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRG 291
Query: 886 ETSREN--KRSQPRVKDSSPGEKSRSQSRERES 916
E+ + + S+P ++ +PG+ Q +S
Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKS 324
Score = 32.0 bits (71), Expect = 4.5
Identities = 20/94 (21%), Positives = 42/94 (44%), Gaps = 2/94 (2%)
Query: 773 PSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQS 832
PS+ P ++P + P + P++ K PQ P P + + ++ ++
Sbjct: 470 PSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKP 529
Query: 833 PSPKNESARGRKKSRSQSPKKDIARERRQSQSRS 866
PS + SA + ++ SP K A++ + S++
Sbjct: 530 PSQQPGSA--KPSAQQPSPAKPSAQQSTKPVSQT 561
Score = 31.6 bits (70), Expect = 5.9
Identities = 41/185 (22%), Positives = 75/185 (40%), Gaps = 19/185 (10%)
Query: 362 AESEKQTRQAPKRKSVRRGRKPPLLKKKLRS-SVAAPEKSSSNDSVDEETAESDTSPVLE 420
+ S + ++Q+PK SV + R + + V EKS S+ + ++E
Sbjct: 4837 SHSSQSSQQSPK-PSVIKSRSHGIFPDPSKDMQVPTIEKSHSSPGSSKSSSEGHL----- 4890
Query: 421 KEHQPDVDSSNICTVQTHVENQSA--NCLKSCNEQIEESEKHTANYDTEERVGSSSSESC 478
+ H P S QTH+E+ A ++ +Q+ N+ E S+ S
Sbjct: 4891 RSHGPSRSQSKTSVTQTHLEDAGAAIAAAEAAVQQLRIQPTKPPNHRPAESSVSTGSSGS 4950
Query: 479 AQDLPVLVGEEGEVKKLENTGIEANVLCLE--SEISENILEKGGDPLEKQDQISGLSQSE 536
+ V EG +T E N+ + ++ +N G +P+++ GL+ +E
Sbjct: 4951 SFGSGYSVDSEGS----SSTAGETNLFPIPRIGKMGQN----GQEPVKQPGVGVGLADTE 5002
Query: 537 VKTDV 541
KT V
Sbjct: 5003 AKTQV 5007
Score = 31.2 bits (69), Expect = 7.7
Identities = 17/71 (23%), Positives = 32/71 (45%), Gaps = 5/71 (7%)
Query: 773 PSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQS 832
PS+ P T ++P + P +T P++ K Q PSP + + ++S K
Sbjct: 500 PSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTK--- 556
Query: 833 PSPKNESARGR 843
P +++ G+
Sbjct: 557 --PVSQTGSGK 565
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.124 0.353
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,241,494
Number of Sequences: 37866
Number of extensions: 3328844
Number of successful extensions: 40051
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 476
Number of HSP's successfully gapped in prelim test: 1346
Number of HSP's that attempted gapping in prelim test: 21142
Number of HSP's gapped (non-prelim): 11195
length of query: 1463
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1348
effective length of database: 13,892,928
effective search space: 18727666944
effective search space used: 18727666944
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.