BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo sapiens] (410 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens] 868 0.0 gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo ... 868 0.0 gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo ... 868 0.0 gi|239753543 PREDICTED: similar to hCG2041108 [Homo sapiens] 216 4e-56 gi|239748119 PREDICTED: similar to hCG2041108 [Homo sapiens] 216 4e-56 gi|239742018 PREDICTED: similar to hCG2041108 [Homo sapiens] 216 4e-56 gi|33186882 testis serine protease 2 [Homo sapiens] 202 3e-52 gi|21614531 testisin isoform 2 [Homo sapiens] 191 1e-48 gi|5803197 testisin isoform 1 [Homo sapiens] 190 2e-48 gi|205360905 testis-specific serine protease 1 [Homo sapiens] 183 2e-46 gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 182 4e-46 gi|58218970 protease, serine, 36 [Homo sapiens] 182 4e-46 gi|116256363 transmembrane protease, serine 13 [Homo sapiens] 180 2e-45 gi|13994276 marapsin [Homo sapiens] 178 7e-45 gi|34098976 marapsin 2 [Homo sapiens] 174 2e-43 gi|148806900 epidermis-specific serine protease-like protein [Ho... 173 3e-43 gi|23957702 transmembrane protease, serine 6 [Homo sapiens] 172 5e-43 gi|21614533 testisin isoform 3 [Homo sapiens] 171 8e-43 gi|11545839 protease, serine, 22 [Homo sapiens] 171 8e-43 gi|156938340 transmembrane tryptase preproprotein [Homo sapiens] 171 8e-43 gi|68508970 tryptase beta 2 precursor [Homo sapiens] 171 1e-42 gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens] 171 1e-42 gi|4506153 prostasin preproprotein [Homo sapiens] 167 2e-41 gi|4503627 coagulation factor XI precursor [Homo sapiens] 166 4e-41 gi|32698940 transmembrane protease, serine 12 [Homo sapiens] 164 2e-40 gi|117956391 protease, serine, 33 [Homo sapiens] 160 1e-39 gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa... 159 6e-39 gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa... 159 6e-39 gi|4758508 transmembrane protease, serine 11D [Homo sapiens] 159 6e-39 gi|187761337 transmembrane protease, serine 11B [Homo sapiens] 157 1e-38 >gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens] Length = 410 Score = 868 bits (2243), Expect = 0.0 Identities = 410/410 (100%), Positives = 410/410 (100%) Query: 1 MASQDGLRRGRGGTRLSLHLLIWLQFLQPLLSEAGSGQGGAGLHPRWVWGGSGGAVGTGR 60 MASQDGLRRGRGGTRLSLHLLIWLQFLQPLLSEAGSGQGGAGLHPRWVWGGSGGAVGTGR Sbjct: 1 MASQDGLRRGRGGTRLSLHLLIWLQFLQPLLSEAGSGQGGAGLHPRWVWGGSGGAVGTGR 60 Query: 61 RGGGAARPAPVRRGSPSSPGEPYRPEEDSRMTPASPEARTSPVHPKFPKIPETSVAPGSP 120 RGGGAARPAPVRRGSPSSPGEPYRPEEDSRMTPASPEARTSPVHPKFPKIPETSVAPGSP Sbjct: 61 RGGGAARPAPVRRGSPSSPGEPYRPEEDSRMTPASPEARTSPVHPKFPKIPETSVAPGSP 120 Query: 121 ATAGPPGSWVTSASTVGEALESDGISDLGRQFSQACGHRVSRMIGGLPAPNKKWPWQVSL 180 ATAGPPGSWVTSASTVGEALESDGISDLGRQFSQACGHRVSRMIGGLPAPNKKWPWQVSL Sbjct: 121 ATAGPPGSWVTSASTVGEALESDGISDLGRQFSQACGHRVSRMIGGLPAPNKKWPWQVSL 180 Query: 181 QTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIGRWDQAWKHLEDIIFPSNF 240 QTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIGRWDQAWKHLEDIIFPSNF Sbjct: 181 QTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIGRWDQAWKHLEDIIFPSNF 240 Query: 241 DFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGTECWVTGWGQVSESVSGPMPL 300 DFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGTECWVTGWGQVSESVSGPMPL Sbjct: 241 DFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGTECWVTGWGQVSESVSGPMPL 300 Query: 301 VLQETELNIMRHEKCCEMLKNKNISKSKMVTRGTVCGYNDQGKDACQGDSGGPLVCELNG 360 VLQETELNIMRHEKCCEMLKNKNISKSKMVTRGTVCGYNDQGKDACQGDSGGPLVCELNG Sbjct: 301 VLQETELNIMRHEKCCEMLKNKNISKSKMVTRGTVCGYNDQGKDACQGDSGGPLVCELNG 360 Query: 361 TWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKWIIDHLRQASCLNSKTSSS 410 TWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKWIIDHLRQASCLNSKTSSS Sbjct: 361 TWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKWIIDHLRQASCLNSKTSSS 410 >gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo sapiens] Length = 410 Score = 868 bits (2243), Expect = 0.0 Identities = 410/410 (100%), Positives = 410/410 (100%) Query: 1 MASQDGLRRGRGGTRLSLHLLIWLQFLQPLLSEAGSGQGGAGLHPRWVWGGSGGAVGTGR 60 MASQDGLRRGRGGTRLSLHLLIWLQFLQPLLSEAGSGQGGAGLHPRWVWGGSGGAVGTGR Sbjct: 1 MASQDGLRRGRGGTRLSLHLLIWLQFLQPLLSEAGSGQGGAGLHPRWVWGGSGGAVGTGR 60 Query: 61 RGGGAARPAPVRRGSPSSPGEPYRPEEDSRMTPASPEARTSPVHPKFPKIPETSVAPGSP 120 RGGGAARPAPVRRGSPSSPGEPYRPEEDSRMTPASPEARTSPVHPKFPKIPETSVAPGSP Sbjct: 61 RGGGAARPAPVRRGSPSSPGEPYRPEEDSRMTPASPEARTSPVHPKFPKIPETSVAPGSP 120 Query: 121 ATAGPPGSWVTSASTVGEALESDGISDLGRQFSQACGHRVSRMIGGLPAPNKKWPWQVSL 180 ATAGPPGSWVTSASTVGEALESDGISDLGRQFSQACGHRVSRMIGGLPAPNKKWPWQVSL Sbjct: 121 ATAGPPGSWVTSASTVGEALESDGISDLGRQFSQACGHRVSRMIGGLPAPNKKWPWQVSL 180 Query: 181 QTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIGRWDQAWKHLEDIIFPSNF 240 QTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIGRWDQAWKHLEDIIFPSNF Sbjct: 181 QTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIGRWDQAWKHLEDIIFPSNF 240 Query: 241 DFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGTECWVTGWGQVSESVSGPMPL 300 DFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGTECWVTGWGQVSESVSGPMPL Sbjct: 241 DFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGTECWVTGWGQVSESVSGPMPL 300 Query: 301 VLQETELNIMRHEKCCEMLKNKNISKSKMVTRGTVCGYNDQGKDACQGDSGGPLVCELNG 360 VLQETELNIMRHEKCCEMLKNKNISKSKMVTRGTVCGYNDQGKDACQGDSGGPLVCELNG Sbjct: 301 VLQETELNIMRHEKCCEMLKNKNISKSKMVTRGTVCGYNDQGKDACQGDSGGPLVCELNG 360 Query: 361 TWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKWIIDHLRQASCLNSKTSSS 410 TWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKWIIDHLRQASCLNSKTSSS Sbjct: 361 TWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKWIIDHLRQASCLNSKTSSS 410 >gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo sapiens] Length = 410 Score = 868 bits (2243), Expect = 0.0 Identities = 410/410 (100%), Positives = 410/410 (100%) Query: 1 MASQDGLRRGRGGTRLSLHLLIWLQFLQPLLSEAGSGQGGAGLHPRWVWGGSGGAVGTGR 60 MASQDGLRRGRGGTRLSLHLLIWLQFLQPLLSEAGSGQGGAGLHPRWVWGGSGGAVGTGR Sbjct: 1 MASQDGLRRGRGGTRLSLHLLIWLQFLQPLLSEAGSGQGGAGLHPRWVWGGSGGAVGTGR 60 Query: 61 RGGGAARPAPVRRGSPSSPGEPYRPEEDSRMTPASPEARTSPVHPKFPKIPETSVAPGSP 120 RGGGAARPAPVRRGSPSSPGEPYRPEEDSRMTPASPEARTSPVHPKFPKIPETSVAPGSP Sbjct: 61 RGGGAARPAPVRRGSPSSPGEPYRPEEDSRMTPASPEARTSPVHPKFPKIPETSVAPGSP 120 Query: 121 ATAGPPGSWVTSASTVGEALESDGISDLGRQFSQACGHRVSRMIGGLPAPNKKWPWQVSL 180 ATAGPPGSWVTSASTVGEALESDGISDLGRQFSQACGHRVSRMIGGLPAPNKKWPWQVSL Sbjct: 121 ATAGPPGSWVTSASTVGEALESDGISDLGRQFSQACGHRVSRMIGGLPAPNKKWPWQVSL 180 Query: 181 QTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIGRWDQAWKHLEDIIFPSNF 240 QTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIGRWDQAWKHLEDIIFPSNF Sbjct: 181 QTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIGRWDQAWKHLEDIIFPSNF 240 Query: 241 DFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGTECWVTGWGQVSESVSGPMPL 300 DFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGTECWVTGWGQVSESVSGPMPL Sbjct: 241 DFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGTECWVTGWGQVSESVSGPMPL 300 Query: 301 VLQETELNIMRHEKCCEMLKNKNISKSKMVTRGTVCGYNDQGKDACQGDSGGPLVCELNG 360 VLQETELNIMRHEKCCEMLKNKNISKSKMVTRGTVCGYNDQGKDACQGDSGGPLVCELNG Sbjct: 301 VLQETELNIMRHEKCCEMLKNKNISKSKMVTRGTVCGYNDQGKDACQGDSGGPLVCELNG 360 Query: 361 TWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKWIIDHLRQASCLNSKTSSS 410 TWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKWIIDHLRQASCLNSKTSSS Sbjct: 361 TWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKWIIDHLRQASCLNSKTSSS 410 >gi|239753543 PREDICTED: similar to hCG2041108 [Homo sapiens] Length = 299 Score = 216 bits (549), Expect = 4e-56 Identities = 152/380 (40%), Positives = 184/380 (48%), Gaps = 112/380 (29%) Query: 1 MASQDGLRRGRGGTRLSLHLLIWLQFLQPLLSEAGSGQGGAGLHPRWVWGGSGGAVGTGR 60 MASQ G SL LL W LQP L EA +G+ GA Sbjct: 1 MASQSGS---------SLGLLAWFLLLQPWLEEARAGRVGAQ------------------ 33 Query: 61 RGGGAARPAPVRRGSPSSPGEPYRPEEDSRMTPASPEARTSPVHPKFPKIPETSVAPGSP 120 GG A P PS PG P + PV APGSP Sbjct: 34 --GGVALLFP--SALPSGPGG---------QDPGASGWEPPPVG-----------APGSP 69 Query: 121 ATAGPPGSWVTSASTVGEALESDGISDLGRQFSQACGHRVSRMIGGLPAPNKKWPWQVSL 180 A G+ V AS + ACG R SR+ GGLPAP++KWPWQVSL Sbjct: 70 AAPQSRGNAVRPASVL---------------LPSACGQRTSRITGGLPAPDRKWPWQVSL 114 Query: 181 QTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIGRWDQAWKHLE-------- 232 QTSN H CGGSLI R WVLTAAHC+ +G+ + HLE Sbjct: 115 QTSNRHICGGSLIARHWVLTAAHCI-------------SGVDPGGSSCSHLEYTVKLGDT 161 Query: 233 ---------------DIIFPSNFDF-ATLTSDIALALLAYSVNYSSHIQPACLPEKLFEV 276 D++ F + +DIALALL + VNYS+HIQ CLPE+ F V Sbjct: 162 NVHHRSKTALVVPVRDVVIHRYFTSPGIIENDIALALLDFPVNYSTHIQLVCLPEQAFMV 221 Query: 277 EAGTECWVTGWGQVSES---VSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTRG 333 +AGT CWVTGWG+V+E+ V+ P QE EL+I+ H+KC E+LK K +S+MV +G Sbjct: 222 QAGTNCWVTGWGKVNETEKIVTEP-----QEAELSIILHDKCNEVLKEKIRMRSEMVKKG 276 Query: 334 TVCGYNDQGKDACQGDSGGP 353 T+CGYNDQGKDACQ GGP Sbjct: 277 TICGYNDQGKDACQ-ILGGP 295 >gi|239748119 PREDICTED: similar to hCG2041108 [Homo sapiens] Length = 299 Score = 216 bits (549), Expect = 4e-56 Identities = 152/380 (40%), Positives = 184/380 (48%), Gaps = 112/380 (29%) Query: 1 MASQDGLRRGRGGTRLSLHLLIWLQFLQPLLSEAGSGQGGAGLHPRWVWGGSGGAVGTGR 60 MASQ G SL LL W LQP L EA +G+ GA Sbjct: 1 MASQSGS---------SLGLLAWFLLLQPWLEEARAGRVGAQ------------------ 33 Query: 61 RGGGAARPAPVRRGSPSSPGEPYRPEEDSRMTPASPEARTSPVHPKFPKIPETSVAPGSP 120 GG A P PS PG P + PV APGSP Sbjct: 34 --GGVALLFP--SALPSGPGG---------QDPGASGWEPPPVG-----------APGSP 69 Query: 121 ATAGPPGSWVTSASTVGEALESDGISDLGRQFSQACGHRVSRMIGGLPAPNKKWPWQVSL 180 A G+ V AS + ACG R SR+ GGLPAP++KWPWQVSL Sbjct: 70 AAPQSRGNAVRPASVL---------------LPSACGQRTSRITGGLPAPDRKWPWQVSL 114 Query: 181 QTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIGRWDQAWKHLE-------- 232 QTSN H CGGSLI R WVLTAAHC+ +G+ + HLE Sbjct: 115 QTSNRHICGGSLIARHWVLTAAHCI-------------SGVDPGGSSCSHLEYTVKLGDT 161 Query: 233 ---------------DIIFPSNFDF-ATLTSDIALALLAYSVNYSSHIQPACLPEKLFEV 276 D++ F + +DIALALL + VNYS+HIQ CLPE+ F V Sbjct: 162 NVHHRSKTALVVPVRDVVIHRYFTSPGIIENDIALALLDFPVNYSTHIQLVCLPEQAFMV 221 Query: 277 EAGTECWVTGWGQVSES---VSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTRG 333 +AGT CWVTGWG+V+E+ V+ P QE EL+I+ H+KC E+LK K +S+MV +G Sbjct: 222 QAGTNCWVTGWGKVNETEKIVTEP-----QEAELSIILHDKCNEVLKEKIRMRSEMVKKG 276 Query: 334 TVCGYNDQGKDACQGDSGGP 353 T+CGYNDQGKDACQ GGP Sbjct: 277 TICGYNDQGKDACQ-ILGGP 295 >gi|239742018 PREDICTED: similar to hCG2041108 [Homo sapiens] Length = 299 Score = 216 bits (549), Expect = 4e-56 Identities = 152/380 (40%), Positives = 184/380 (48%), Gaps = 112/380 (29%) Query: 1 MASQDGLRRGRGGTRLSLHLLIWLQFLQPLLSEAGSGQGGAGLHPRWVWGGSGGAVGTGR 60 MASQ G SL LL W LQP L EA +G+ GA Sbjct: 1 MASQSGS---------SLGLLAWFLLLQPWLEEARAGRVGAQ------------------ 33 Query: 61 RGGGAARPAPVRRGSPSSPGEPYRPEEDSRMTPASPEARTSPVHPKFPKIPETSVAPGSP 120 GG A P PS PG P + PV APGSP Sbjct: 34 --GGVALLFP--SALPSGPGG---------QDPGASGWEPPPVG-----------APGSP 69 Query: 121 ATAGPPGSWVTSASTVGEALESDGISDLGRQFSQACGHRVSRMIGGLPAPNKKWPWQVSL 180 A G+ V AS + ACG R SR+ GGLPAP++KWPWQVSL Sbjct: 70 AAPQSRGNAVRPASVL---------------LPSACGQRTSRITGGLPAPDRKWPWQVSL 114 Query: 181 QTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIGRWDQAWKHLE-------- 232 QTSN H CGGSLI R WVLTAAHC+ +G+ + HLE Sbjct: 115 QTSNRHICGGSLIARHWVLTAAHCI-------------SGVDPGGSSCSHLEYTVKLGDT 161 Query: 233 ---------------DIIFPSNFDF-ATLTSDIALALLAYSVNYSSHIQPACLPEKLFEV 276 D++ F + +DIALALL + VNYS+HIQ CLPE+ F V Sbjct: 162 NVHHRSKTALVVPVRDVVIHRYFTSPGIIENDIALALLDFPVNYSTHIQLVCLPEQAFMV 221 Query: 277 EAGTECWVTGWGQVSES---VSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTRG 333 +AGT CWVTGWG+V+E+ V+ P QE EL+I+ H+KC E+LK K +S+MV +G Sbjct: 222 QAGTNCWVTGWGKVNETEKIVTEP-----QEAELSIILHDKCNEVLKEKIRMRSEMVKKG 276 Query: 334 TVCGYNDQGKDACQGDSGGP 353 T+CGYNDQGKDACQ GGP Sbjct: 277 TICGYNDQGKDACQ-ILGGP 295 >gi|33186882 testis serine protease 2 [Homo sapiens] Length = 293 Score = 202 bits (515), Expect = 3e-52 Identities = 113/273 (41%), Positives = 156/273 (57%), Gaps = 32/273 (11%) Query: 111 PETSVAPGSPATAGPPGSWVTSASTVGEALESDGISDLGRQFSQACGHRVSRMIGGLPAP 170 PE S APG A GPP + TS G++L CG R++GG+ A Sbjct: 46 PEASPAPGPEA--GPPLNLFTSFP--GDSL--------------LCGRTPLRIVGGVDAE 87 Query: 171 NKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCV---FRGCGWEGGRWLL----AGIGR 223 +WPWQVS++T H CGG+L+ WVLTA HC+ F G R + + + Sbjct: 88 EGRWPWQVSVRTKGRHICGGTLVTATWVLTAGHCISSRFHYSVKMGDRSVYNENTSVVVS 147 Query: 224 WDQAWKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGTECW 283 +A+ H P T+ +D+AL L + VN++S+IQP C+P++ F+VE T CW Sbjct: 148 VQRAFVH------PKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCW 201 Query: 284 VTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTRGTVCGYNDQGK 343 VTGWG+ E +LQ+ + IM +E+C ++++ S ++ +G VCGY +QGK Sbjct: 202 VTGWGKTPEREKLASE-ILQDVDQYIMCYEECNKIIQKALSSTKDVIIKGMVCGYKEQGK 260 Query: 344 DACQGDSGGPLVCELNGTWVQVGIVSWGIGCGR 376 D+CQGDSGG L CE N TWVQVGIVSWGIGCGR Sbjct: 261 DSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR 293 >gi|21614531 testisin isoform 2 [Homo sapiens] Length = 312 Score = 191 bits (485), Expect = 1e-48 Identities = 105/252 (41%), Positives = 134/252 (53%), Gaps = 13/252 (5%) Query: 153 SQACGHRV--SRMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCVFRGCG 210 S CG RV SR++GG A +WPWQ SL+ + H CG SL+ RW LTAAHC Sbjct: 30 SGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETDLS 89 Query: 211 WEGGRWLLAG-IGRWDQAW-------KHLEDIIFPSNFDFATLTSDIALALLAYSVNYSS 262 G + G + W ++ I+ S DIAL L+ V Y+ Sbjct: 90 DPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTK 149 Query: 263 HIQPACLPEKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNK 322 HIQP CL FE E T+CWVTGWG + E + P P LQE ++ I+ + C + Sbjct: 150 HIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKY 209 Query: 323 NISKSKMVTRGTVCGYNDQG-KDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPG 381 + K + VC N QG KDAC GDSGGPL C NG W Q+G+VSWG+GCGR PG Sbjct: 210 SFRKD--IFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPG 267 Query: 382 VYTEVSFYKKWI 393 VYT +S + +WI Sbjct: 268 VYTNISHHFEWI 279 >gi|5803197 testisin isoform 1 [Homo sapiens] Length = 314 Score = 190 bits (483), Expect = 2e-48 Identities = 108/254 (42%), Positives = 138/254 (54%), Gaps = 15/254 (5%) Query: 153 SQACGHRV--SRMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHC------ 204 S CG RV SR++GG A +WPWQ SL+ + H CG SL+ RW LTAAHC Sbjct: 30 SGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSD 89 Query: 205 VFRGCGWEGGRWLLAGIGR-WD-QAW--KHLEDIIFPSNFDFATLTSDIALALLAYSVNY 260 + GW L + W QA+ ++ I+ S DIAL L+ V Y Sbjct: 90 LSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTY 149 Query: 261 SSHIQPACLPEKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLK 320 + HIQP CL FE E T+CWVTGWG + E + P P LQE ++ I+ + C + Sbjct: 150 TKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFL 209 Query: 321 NKNISKSKMVTRGTVCGYNDQG-KDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGY 379 + K + VC N QG KDAC GDSGGPL C NG W Q+G+VSWG+GCGR Sbjct: 210 KYSFRKD--IFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNR 267 Query: 380 PGVYTEVSFYKKWI 393 PGVYT +S + +WI Sbjct: 268 PGVYTNISHHFEWI 281 >gi|205360905 testis-specific serine protease 1 [Homo sapiens] Length = 318 Score = 183 bits (465), Expect = 2e-46 Identities = 108/288 (37%), Positives = 149/288 (51%), Gaps = 26/288 (9%) Query: 121 ATAGPPGSWVTSASTVGEALESDGISDLGRQFSQACGHRVSRMI--GGLPAPNKKWPWQV 178 A G PG + G A G GR+ +ACGHR + GG+ + +WPWQ Sbjct: 16 AGLGKPGELGALQAGPGAARRPGGG---GRE--EACGHREIHALVAGGVESARGRWPWQA 70 Query: 179 SLQTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLA-----------GIGRWDQA 227 SL+ H CGGSL+ RRWVL+AAHC + + W + + + Sbjct: 71 SLRLRRRHRCGGSLLSRRWVLSAAHCFQKH--YYPSEWTVQLGELTSRPTPWNLRAYSSR 128 Query: 228 WKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGTECWVTGW 287 +K + I+ P L +DIAL LA SV Y+++IQP C+ F +CWVTGW Sbjct: 129 YKVQDIIVNPDAL--GVLRNDIALLRLASSVTYNAYIQPICIESSTFNFVHRPDCWVTGW 186 Query: 288 GQVSESVSG-PMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTRGTVC-GYNDQGKDA 345 G +S S + P P L+E ++ I+ + +C + + S M+ C G D D Sbjct: 187 GLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQP--SSRSMIWDSMFCAGAEDGSVDT 244 Query: 346 CQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKWI 393 C+GDSGGPLVC+ +G W QVGIVSWG+ CG+ PGVYT +S Y WI Sbjct: 245 CKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNISVYFHWI 292 >gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] Length = 638 Score = 182 bits (463), Expect = 4e-46 Identities = 101/243 (41%), Positives = 137/243 (56%), Gaps = 16/243 (6%) Query: 161 SRMIGGLPAPNKKWPWQVSLQ---TSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWL 217 +R++GG + +WPWQVSLQ T+ H CGGSLI +WVLTAAHC F G + + Sbjct: 389 TRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHC-FDGLPLQDVWRI 447 Query: 218 LAGIGRW-----DQAWKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEK 272 +GI D + +++II N+ + DIAL L +NY+ +P CLP K Sbjct: 448 YSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSK 507 Query: 273 LFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTR 332 T CWVTGWG E G + +LQ+ + ++ +E+C K K+ R Sbjct: 508 GDTSTIYTNCWVTGWGFSKEK--GEIQNILQKVNIPLVTNEEC-----QKRYQDYKITQR 560 Query: 333 GTVCGYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKW 392 GY + GKDAC+GDSGGPLVC+ NG W VGI SWG GC R+ PGVYT+V+ Y W Sbjct: 561 MVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDW 620 Query: 393 IID 395 I++ Sbjct: 621 ILE 623 >gi|58218970 protease, serine, 36 [Homo sapiens] Length = 855 Score = 182 bits (463), Expect = 4e-46 Identities = 101/242 (41%), Positives = 132/242 (54%), Gaps = 9/242 (3%) Query: 161 SRMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWE-GGRW-LL 218 +R++GG A WPWQVSL H CGGSLI WVL+AAHC E W +L Sbjct: 45 ARIVGGSNAQPGTWPWQVSLHHGGGHICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVL 104 Query: 219 AGI----GRWDQAW-KHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEKL 273 G+ G D A + + I+ P+N+ L +D+AL LA + + P CLP Sbjct: 105 LGVHSQDGPLDGAHTRAVAAIVVPANYSQVELGADLALLRLASPASLGPAVWPVCLPRAS 164 Query: 274 FEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKC-CEMLKNKNISKSKMVTR 332 GT CW TGWG V E+ P+P VLQE EL ++ C C + + + + Sbjct: 165 HRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCLYSQPGPFNLTLQILP 224 Query: 333 GTVC-GYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYKK 391 G +C GY + +D CQGDSGGPLVCE G W Q GI S+G GCGR+ PGV+T V+ Y+ Sbjct: 225 GMLCAGYPEGRRDTCQGDSGGPLVCEEGGRWFQAGITSFGFGCGRRNRPGVFTAVATYEA 284 Query: 392 WI 393 WI Sbjct: 285 WI 286 Score = 62.4 bits (150), Expect = 7e-10 Identities = 68/263 (25%), Positives = 104/263 (39%), Gaps = 32/263 (12%) Query: 122 TAGPPGSWVTSASTVGEALESDGISDLGRQFSQACGHRVSRMIGGL---PAP-NKKWPWQ 177 T GP S VT + + + L D D +Q C GL AP WPW Sbjct: 545 THGPWISHVTRGAYLEDQLAWDWGPDGEETETQTCPPHTEHGACGLRLEAAPVGVLWPWL 604 Query: 178 VSLQTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEG-------GRWLLAGIGRWDQAWKH 230 + + C G L+ WVL A HCV R GR + + + Q + Sbjct: 605 AEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLPQGHQVSRL 664 Query: 231 LEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGTECWVTGWGQV 290 + I P + L +AL L+ V S P CL + G CWV GW + Sbjct: 665 VISIRLPQHLG---LRPPLALLELSSRVEPSPSALPICLHPA--GIPPGASCWVLGWKEP 719 Query: 291 SESVSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTRGTVCGYNDQGKD-ACQGD 349 + V P+ + L ++ C+ L ++ GT+C +G++ C+ Sbjct: 720 QDRV----PVAAAVSILT----QRICDCL------YQGILPPGTLCVLYAEGQENRCEMT 765 Query: 350 SGGPLVCEL-NGTWVQVGIVSWG 371 S PL+C++ G+W+ VG+ G Sbjct: 766 SAPPLLCQMTEGSWILVGMAVQG 788 Score = 60.8 bits (146), Expect = 2e-09 Identities = 63/250 (25%), Positives = 99/250 (39%), Gaps = 21/250 (8%) Query: 165 GGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCVFRGCG-------WEGGRWL 217 G P P WPW+ + C G+L+ WVL A C + R L Sbjct: 326 GKAPRPGA-WPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRVL 384 Query: 218 LAGIGRWDQAWKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVE 277 L R ++ + ++ +++D A SD+AL L VN S+ +P CLP Sbjct: 385 LPSRPRAERVARLVQH--ENASWDNA---SDLALLQLRTPVNLSAASRPVCLPHPEHYFL 439 Query: 278 AGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTRGTVCG 337 G+ C + WG+ E GP L+ E EL C + + Sbjct: 440 PGSRCRLARWGR-GEPALGPGALL--EAELLGGWWCHCLYGRQGAAVPLPGDPPHALCPA 496 Query: 338 YNDQGK-DACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKWIIDH 396 Y ++ + +C DS L+C+ GTW GI + GC R P + + + W I H Sbjct: 497 YQEKEEVGSCWNDSRWSLLCQEEGTWFLAGIRDFPSGCLR---PRAFFPLQTHGPW-ISH 552 Query: 397 LRQASCLNSK 406 + + + L + Sbjct: 553 VTRGAYLEDQ 562 >gi|116256363 transmembrane protease, serine 13 [Homo sapiens] Length = 567 Score = 180 bits (456), Expect = 2e-45 Identities = 106/269 (39%), Positives = 144/269 (53%), Gaps = 16/269 (5%) Query: 134 STVGEALESDGISDLGRQFSQACGH-----RVSRMIGGLPAPNKKWPWQVSLQTSNIHHC 188 ST+ E+L R S C H R++GG A + KWPWQVSL H C Sbjct: 293 STIQESLHRSECPSQ-RYISLQCSHCGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHIC 351 Query: 189 GGSLIDRRWVLTAAHCVF--RGCGWEGGRWLLAGIGRWDQAWK--HLEDIIFPSNFDFAT 244 GG+LID +WVLTAAHC F R EG + + AG Q + + +II SN+ Sbjct: 352 GGTLIDAQWVLTAAHCFFVTREKVLEGWK-VYAGTSNLHQLPEAASIAEIIINSNYTDEE 410 Query: 245 LTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQE 304 DIAL L+ + S+HI PACLP CW+TG+G+ E+ P L+E Sbjct: 411 DDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPF-LRE 469 Query: 305 TELNIMRHEKCCEMLKNKNISKSKMVTRGTVCGYNDQGKDACQGDSGGPLVCELNGTWVQ 364 ++N++ +KC + L + +M+ G + G G+D+CQGDSGGPLVCE N W Sbjct: 470 VQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRG----GRDSCQGDSGGPLVCEQNNRWYL 525 Query: 365 VGIVSWGIGCGRKGYPGVYTEVSFYKKWI 393 G+ SWG GCG++ PGVYT+V+ WI Sbjct: 526 AGVTSWGTGCGQRNKPGVYTKVTEVLPWI 554 Score = 30.0 bits (66), Expect = 4.0 Identities = 28/105 (26%), Positives = 37/105 (35%), Gaps = 7/105 (6%) Query: 51 GSGGAVGTGRRGGGAARPAPVRRGSPSSPGEPYRPEEDSRMTPASPEARTSPVHPKFPKI 110 G+ T G A+ +P G+P P + +P R SP Sbjct: 7 GNASPARTPSAGASPAQASPA--GTPPGRASPAQASPAQASPAGTPPGRASPAQASPAGT 64 Query: 111 PETSVAPG--SPATAGPPGSWVTSASTVGEALESDGISDLGRQFS 153 P +PG SPA A P + S + AL S S GR S Sbjct: 65 PPGRASPGRASPAQASPAQA---SPARASPALASLSRSSSGRSSS 106 >gi|13994276 marapsin [Homo sapiens] Length = 290 Score = 178 bits (452), Expect = 7e-45 Identities = 97/250 (38%), Positives = 138/250 (55%), Gaps = 13/250 (5%) Query: 155 ACGH--RVSRMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWE 212 ACG ++RM+GG +WPWQVS+Q + H CGGSLI +WVLTAAHC FR Sbjct: 25 ACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHC-FRNTSET 83 Query: 213 GGRWLLAGIGRWDQAWKH-----LEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPA 267 +L G + Q H + + + ++D+AL L V ++++I P Sbjct: 84 SLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPV 143 Query: 268 CLPEKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNIS-- 325 CLP+ E G CWVTGWG SE P P +LQ+ + I+ KC +L +K+ Sbjct: 144 CLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKC-NLLYSKDTEFG 202 Query: 326 -KSKMVTRGTVC-GYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVY 383 + K + +C G+ + KDAC+GDSGGPLVC + +W+Q G++SWG GC R+ PGVY Sbjct: 203 YQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVY 262 Query: 384 TEVSFYKKWI 393 V+ + WI Sbjct: 263 IRVTAHHNWI 272 >gi|34098976 marapsin 2 [Homo sapiens] Length = 326 Score = 174 bits (440), Expect = 2e-43 Identities = 100/272 (36%), Positives = 144/272 (52%), Gaps = 17/272 (6%) Query: 133 ASTVGEALESDGISDLGRQFSQACGH--RVSRMIGGLPAPNKKWPWQVSLQTSNIHHCGG 190 A+ V E+ GIS G S ACG +++GG+PAP +KWPWQVS+ + +H CGG Sbjct: 31 AALVHRQPENQGISLTG---SVACGRPSMEGKILGGVPAPERKWPWQVSVHYAGLHVCGG 87 Query: 191 SLIDRRWVLTAAHCVFRGCGWE-----GGRWLLAGIGRWDQAWKHLEDIIFPSNFDFATL 245 S+++ WVL+AAHC R + G L G Q ++ I+ P+ + + Sbjct: 88 SILNEYWVLSAAHCFHRDKNIKIYDMYVGLVNLRVAGNHTQWYEVNRVILHPTYEMYHPI 147 Query: 246 TSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQET 305 D+AL L + +S + P CL + + CW TGWG VS+ G LQE Sbjct: 148 GGDVALVQLKTRIVFSESVLPVCLATPEVNLTSAN-CWATGWGLVSKQ--GETSDELQEM 204 Query: 306 ELNIMRHEKCCEMLKNKNISKSKMVTRGTVCGYNDQGKDACQGDSGGPLVCELNGTWVQV 365 +L ++ C + + + M+ G + K C+GDSGGPLVCE N +W+Q+ Sbjct: 205 QLPLILEPWCHLLYGHMSYIMPDMLCAGDILN----AKTVCEGDSGGPLVCEFNRSWLQI 260 Query: 366 GIVSWGIGCGRKGYPGVYTEVSFYKKWIIDHL 397 GIVSWG GC YPGVY VS++ KWI D++ Sbjct: 261 GIVSWGRGCSNPLYPGVYASVSYFSKWICDNI 292 >gi|148806900 epidermis-specific serine protease-like protein [Homo sapiens] Length = 328 Score = 173 bits (438), Expect = 3e-43 Identities = 100/261 (38%), Positives = 142/261 (54%), Gaps = 18/261 (6%) Query: 156 CGHRV--SRMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCV------FR 207 CG V SR++GG A +WPWQVSL + CGGSL+ R +LTAAHC+ F Sbjct: 19 CGQPVYSSRVVGGQDAAAGRWPWQVSLHFDHNFICGGSLVSERLILTAAHCIQPTWTTFS 78 Query: 208 GCGWEGGRWLLAGIGRWDQAWKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPA 267 W G + G R + + +I P D T+D+AL L+ V ++S I P Sbjct: 79 YTVWLGS--ITVGDSRKRVKYYVSKIVIHPKYQD---TTADVALLKLSSQVTFTSAILPI 133 Query: 268 CLPEKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNI--- 324 CLP ++ CWVTGWG+V ES LQE E+ I+ + C ++ I Sbjct: 134 CLPSVTKQLAIPPFCWVTGWGKVKESSDRDYHSALQEAEVPIIDRQACEQLYNPIGIFLP 193 Query: 325 SKSKMVTRGTVCGYNDQG-KDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVY 383 + ++ +C + Q KD+C+GDSGGPL C ++G W+Q G+VSWG+ CG K PGVY Sbjct: 194 ALEPVIKEDKICAGDTQNMKDSCKGDSGGPLSCHIDGVWIQTGVVSWGLECG-KSLPGVY 252 Query: 384 TEVSFYKKWIIDHLRQASCLN 404 T V +Y+KWI + +A+ L+ Sbjct: 253 TNVIYYQKWINATISRANNLD 273 >gi|23957702 transmembrane protease, serine 6 [Homo sapiens] Length = 811 Score = 172 bits (436), Expect = 5e-43 Identities = 94/247 (38%), Positives = 134/247 (54%), Gaps = 29/247 (11%) Query: 161 SRMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHC-------------VFR 207 SR++GG + +WPWQ SLQ H CGG+LI RWV+TAAHC VF Sbjct: 575 SRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFL 634 Query: 208 GCGWEGGRWLLAGIGRWDQAWKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPA 267 G W+ RW + ++K ++ P + + + D+AL L + V S+ ++P Sbjct: 635 GKVWQNSRW------PGEVSFKVSRLLLHPYH-EEDSHDYDVALLQLDHPVVRSAAVRPV 687 Query: 268 CLPEKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNISKS 327 CLP + E G CW+TGWG + E GP+ LQ+ ++ ++ + C E + + Sbjct: 688 CLPARSHFFEPGLHCWITGWGALRE--GGPISNALQKVDVQLIPQDLCSE------VYRY 739 Query: 328 KMVTRGTVCGYNDQGKDACQGDSGGPLVCE-LNGTWVQVGIVSWGIGCGRKGYPGVYTEV 386 ++ R GY KDACQGDSGGPLVC+ L+G W G+VSWG+GCGR Y GVYT + Sbjct: 740 QVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRI 799 Query: 387 SFYKKWI 393 + WI Sbjct: 800 TGVISWI 806 >gi|21614533 testisin isoform 3 [Homo sapiens] Length = 300 Score = 171 bits (434), Expect = 8e-43 Identities = 100/253 (39%), Positives = 130/253 (51%), Gaps = 27/253 (10%) Query: 153 SQACGHRV--SRMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHC------ 204 S CG RV SR++GG A +WPWQ SL+ + H CG SL+ RW LTAAHC Sbjct: 30 SGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSD 89 Query: 205 VFRGCGWEGGRWLLAGIGR-WD-QAW--KHLEDIIFPSNFDFATLTSDIALALLAYSVNY 260 + GW L + W QA+ ++ I+ S DIAL L+ V Y Sbjct: 90 LSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTY 149 Query: 261 SSHIQPACLPEKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLK 320 + HIQP CL FE E T+CWVTGWG + E + P P LQE ++ I+ + C + Sbjct: 150 TKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFL 209 Query: 321 NKNISKSKMVTRGTVCGYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYP 380 + K + D G DSGGPL C NG W Q+G+VSWG+GCGR P Sbjct: 210 KYSFRKDI---------FGDMG------DSGGPLACNKNGLWYQIGVVSWGVGCGRPNRP 254 Query: 381 GVYTEVSFYKKWI 393 GVYT +S + +WI Sbjct: 255 GVYTNISHHFEWI 267 >gi|11545839 protease, serine, 22 [Homo sapiens] Length = 317 Score = 171 bits (434), Expect = 8e-43 Identities = 89/252 (35%), Positives = 132/252 (52%), Gaps = 19/252 (7%) Query: 155 ACG--HRVSRMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWE 212 ACG +++R++GG + + +WPW VS+Q + HHC GSL+ RWV+TAAHC Sbjct: 40 ACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKP 99 Query: 213 G------GRWLLAGIGRWDQ----AWKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSS 262 G W L G Q AW + A DIAL L S+ +S Sbjct: 100 YLFSVLLGAWQLGNPGSRSQKVGVAWVEPHPVYSWKEGACA----DIALVRLERSIQFSE 155 Query: 263 HIQPACLPEKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNK 322 + P CLP+ + T CW++GWG + + V P P LQ+ ++ I+ E C + Sbjct: 156 RVLPICLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRG 215 Query: 323 NISKSKMVTRGTVC-GYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPG 381 + +T +C GY + +DAC GDSGGPL+C+++G W+ GI+SWG GC + PG Sbjct: 216 --AGQGPITEDMLCAGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPG 273 Query: 382 VYTEVSFYKKWI 393 VY +S ++ W+ Sbjct: 274 VYISLSAHRSWV 285 >gi|156938340 transmembrane tryptase preproprotein [Homo sapiens] Length = 321 Score = 171 bits (434), Expect = 8e-43 Identities = 99/241 (41%), Positives = 123/241 (51%), Gaps = 13/241 (5%) Query: 162 RMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGI 221 R++GG AP WPWQ SL+ +H CGGSL+ +WVLTAAHC + L + Sbjct: 37 RIVGGHAAPAGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLNSSDYQVHLGEL 96 Query: 222 G-RWDQAWKHLEDIIFPSNFDFATLTS-DIALALLAYSVNYSSHIQPACLPEKLFEVEAG 279 + + II S+ TS DIAL L+ V SS I P CLPE + G Sbjct: 97 EITLSPHFSTVRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPG 156 Query: 280 TECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKN---ISKSKMVTRGTVC 336 CWVTGWG E P P L+E +++++ E C + + RG Sbjct: 157 IRCWVTGWGYTREGEPLPPPYSLREVKVSVVDTETCRRDYPGPGGSILQPDMLCARGP-- 214 Query: 337 GYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKWIIDH 396 DACQ DSGGPLVC++NG WVQ GIVSWG GCGR PGVYT V Y WI H Sbjct: 215 ------GDACQDDSGGPLVCQVNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRH 268 Query: 397 L 397 + Sbjct: 269 I 269 >gi|68508970 tryptase beta 2 precursor [Homo sapiens] Length = 275 Score = 171 bits (433), Expect = 1e-42 Identities = 97/243 (39%), Positives = 132/243 (54%), Gaps = 18/243 (7%) Query: 163 MIGGLPAPNKKWPWQVSLQTSN---IHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLA 219 ++GG AP KWPWQVSL+ + +H CGGSLI +WVLTAAHCV + L A Sbjct: 31 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCVGPDV-----KDLAA 85 Query: 220 GIGRWDQAWKHLEDIIFPSN-------FDFATLTSDIALALLAYSVNYSSHIQPACLPEK 272 + + + +D + P + F A + +DIAL L VN SSH+ LP Sbjct: 86 LRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPA 145 Query: 273 LFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEM--LKNKNISKSKMV 330 G CWVTGWG V P P L++ ++ IM + C L ++V Sbjct: 146 SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 205 Query: 331 TRGTVCGYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYK 390 +C N + +D+CQGDSGGPLVC++NGTW+Q G+VSWG GC + PG+YT V++Y Sbjct: 206 RDDMLCAGNTR-RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264 Query: 391 KWI 393 WI Sbjct: 265 DWI 267 >gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens] Length = 275 Score = 171 bits (432), Expect = 1e-42 Identities = 97/243 (39%), Positives = 131/243 (53%), Gaps = 18/243 (7%) Query: 163 MIGGLPAPNKKWPWQVSLQTSN---IHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLA 219 ++GG AP KWPWQVSL+ +H CGGSLI +WVLTAAHCV + L A Sbjct: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDV-----KDLAA 85 Query: 220 GIGRWDQAWKHLEDIIFPSN-------FDFATLTSDIALALLAYSVNYSSHIQPACLPEK 272 + + + +D + P + F A + +DIAL L VN SSH+ LP Sbjct: 86 LRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPA 145 Query: 273 LFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEM--LKNKNISKSKMV 330 G CWVTGWG V P P L++ ++ IM + C L ++V Sbjct: 146 SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 205 Query: 331 TRGTVCGYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYK 390 +C N + +D+CQGDSGGPLVC++NGTW+Q G+VSWG GC + PG+YT V++Y Sbjct: 206 RDDMLCAGNTR-RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264 Query: 391 KWI 393 WI Sbjct: 265 DWI 267 >gi|4506153 prostasin preproprotein [Homo sapiens] Length = 343 Score = 167 bits (423), Expect = 2e-41 Identities = 97/240 (40%), Positives = 127/240 (52%), Gaps = 8/240 (3%) Query: 161 SRMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAG 220 +R+ GG A +WPWQVS+ +H CGGSL+ +WVL+AAHC F + + G Sbjct: 43 ARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHC-FPSEHHKEAYEVKLG 101 Query: 221 IGRWDQAWKH-----LEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEKLFE 275 + D + L+DII ++ DIAL L+ + +S +I+P CLP Sbjct: 102 AHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANAS 161 Query: 276 VEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKC-CEMLKNKNISKSKMVTRGT 334 G C VTGWG V+ SVS P LQ+ E+ ++ E C C + + V Sbjct: 162 FPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDM 221 Query: 335 VC-GYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKWI 393 VC GY + GKDACQGDSGGPL C + G W GIVSWG CG + PGVYT S Y WI Sbjct: 222 VCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWI 281 >gi|4503627 coagulation factor XI precursor [Homo sapiens] Length = 625 Score = 166 bits (420), Expect = 4e-41 Identities = 93/244 (38%), Positives = 136/244 (55%), Gaps = 20/244 (8%) Query: 162 RMIGGLPAPNKKWPWQVSLQTSNI---HHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLL 218 R++GG + +WPWQV+L T++ H CGGS+I +W+LTAAHC + G E + L Sbjct: 387 RIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFY---GVESPKILR 443 Query: 219 AGIG-------RWDQAWKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPE 271 G + D ++ +++II + A DIAL L +VNY+ +P CLP Sbjct: 444 VYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPS 503 Query: 272 KLFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVT 331 K T+CWVTGWG + + LQ+ ++ ++ +E+C + + I+ KM+ Sbjct: 504 KGDRNVIYTDCWVTGWGY--RKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITH-KMIC 560 Query: 332 RGTVCGYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYKK 391 GY + GKDAC+GDSGGPL C+ N W VGI SWG GC ++ PGVYT V Y Sbjct: 561 ----AGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVD 616 Query: 392 WIID 395 WI++ Sbjct: 617 WILE 620 >gi|32698940 transmembrane protease, serine 12 [Homo sapiens] Length = 348 Score = 164 bits (414), Expect = 2e-40 Identities = 97/253 (38%), Positives = 138/253 (54%), Gaps = 19/253 (7%) Query: 161 SRMIGGLPAPNKKWPWQVSLQTSN----IHHCGGSLIDRRWVLTAAHCVFRGCG---WEG 213 SR+IGG A WPW VSLQ +H CGG+L+ RWVLTAAHC W Sbjct: 76 SRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDASDPLMWTA 135 Query: 214 GRWLLAGIGRWDQAWK-HLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEK 272 GR+ K ++ II NF + +DIAL L +V Y+ +IQP CLP Sbjct: 136 VIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFD 195 Query: 273 LFEV-EAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVT 331 +F++ + T+C+++GWG+ E G +LQ+ E++ + E C N S ++ Sbjct: 196 VFQILDGNTKCFISGWGRTKEE--GNATNILQDAEVHYISREMC-----NSERSYGGIIP 248 Query: 332 RGTVCGYNDQGK-DACQGDSGGPLVCELNG--TWVQVGIVSWGIGCGRKGYPGVYTEVSF 388 + C ++ G D C+GDSGGPL+C L + +GI S+G GCGR+G+PGVY SF Sbjct: 249 NTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSF 308 Query: 389 YKKWIIDHLRQAS 401 Y+KW+ +H AS Sbjct: 309 YQKWLTEHFFHAS 321 >gi|117956391 protease, serine, 33 [Homo sapiens] Length = 280 Score = 160 bits (406), Expect = 1e-39 Identities = 97/251 (38%), Positives = 128/251 (50%), Gaps = 11/251 (4%) Query: 153 SQACGH--RVSRMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCVFRGCG 210 S ACG SR++GG + +WPWQ S+Q H CGGSLI +WVLTAAHC R Sbjct: 25 SAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRAL 84 Query: 211 WEGGRWLLAGIGRWDQAWKHLE----DIIFPSNFDFATLTSDIALALLAYSVNYSSHIQP 266 R L + + + L ++ P ++ D+AL L V S+ +QP Sbjct: 85 PAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARVQP 144 Query: 267 ACLPEKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNIS- 325 CLP GT C VTGWG + V P LQ + ++ + C+ L + Sbjct: 145 VCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLL-DSRTCDGLYHVGADV 203 Query: 326 --KSKMVTRGTVC-GYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGV 382 ++V G++C GY KDACQGDSGGPL C +G+WV VG+VSWG GC PGV Sbjct: 204 PQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPGV 263 Query: 383 YTEVSFYKKWI 393 YT V+ Y WI Sbjct: 264 YTSVATYSPWI 274 >gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sapiens] Length = 529 Score = 159 bits (401), Expect = 6e-39 Identities = 88/254 (34%), Positives = 125/254 (49%), Gaps = 17/254 (6%) Query: 155 ACG-----HRVSRMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCVFRGC 209 ACG R SR++GG A WPWQVSL N+H CGGS+I W++TAAHCV + Sbjct: 280 ACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPL 339 Query: 210 G----WEGGRWLLAGIGRWDQAWKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQ 265 W +L + A +E +I N+D T +DIAL L + ++ ++ Sbjct: 340 NNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVK 399 Query: 266 PACLPEKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNIS 325 P CLP ++ CW++GWG E G VL ++ ++ ++C N Sbjct: 400 PVCLPNPGMMLQPEQLCWISGWGATEE--KGKTSEVLNAAKVLLIETQRC-----NSRYV 452 Query: 326 KSKMVTRGTVC-GYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYT 384 ++T +C G+ D+CQGDSGGPLV N W +G SWG GC + PGVY Sbjct: 453 YDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYG 512 Query: 385 EVSFYKKWIIDHLR 398 V + WI +R Sbjct: 513 NVMVFTDWIYRQMR 526 >gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sapiens] Length = 492 Score = 159 bits (401), Expect = 6e-39 Identities = 88/254 (34%), Positives = 125/254 (49%), Gaps = 17/254 (6%) Query: 155 ACG-----HRVSRMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCVFRGC 209 ACG R SR++GG A WPWQVSL N+H CGGS+I W++TAAHCV + Sbjct: 243 ACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPL 302 Query: 210 G----WEGGRWLLAGIGRWDQAWKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQ 265 W +L + A +E +I N+D T +DIAL L + ++ ++ Sbjct: 303 NNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVK 362 Query: 266 PACLPEKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNIS 325 P CLP ++ CW++GWG E G VL ++ ++ ++C N Sbjct: 363 PVCLPNPGMMLQPEQLCWISGWGATEE--KGKTSEVLNAAKVLLIETQRC-----NSRYV 415 Query: 326 KSKMVTRGTVC-GYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYT 384 ++T +C G+ D+CQGDSGGPLV N W +G SWG GC + PGVY Sbjct: 416 YDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYG 475 Query: 385 EVSFYKKWIIDHLR 398 V + WI +R Sbjct: 476 NVMVFTDWIYRQMR 489 >gi|4758508 transmembrane protease, serine 11D [Homo sapiens] Length = 418 Score = 159 bits (401), Expect = 6e-39 Identities = 94/235 (40%), Positives = 128/235 (54%), Gaps = 11/235 (4%) Query: 162 RMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGI 221 R++GG A WPWQVSL+ +N HHCGGSLI+ W+LTAAHC FR +GI Sbjct: 186 RILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHC-FRSNSNPRDWIATSGI 244 Query: 222 G-RWDQAWKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGT 280 + + + +I+ +N+ AT +DIAL L SV ++ I CLP + G+ Sbjct: 245 STTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNIPPGS 304 Query: 281 ECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTRGTVC-GYN 339 +VTGWG ++ +G L++ ++ I+ ++ C N S + + G +C G Sbjct: 305 TAYVTGWG--AQEYAGHTVPELRQGQVRIISNDVC-----NAPHSYNGAILSGMLCAGVP 357 Query: 340 DQGKDACQGDSGGPLVCE-LNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKWI 393 G DACQGDSGGPLV E W VGIVSWG CG PGVYT V+ Y WI Sbjct: 358 QGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWI 412 >gi|187761337 transmembrane protease, serine 11B [Homo sapiens] Length = 416 Score = 157 bits (398), Expect = 1e-38 Identities = 90/250 (36%), Positives = 132/250 (52%), Gaps = 16/250 (6%) Query: 153 SQACGHRVS-------RMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCV 205 + CG +V+ +++ G + WPWQ S+Q H+CG SLI RW+L+AAHC Sbjct: 168 NNCCGRQVANSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCF 227 Query: 206 FRGCGWEGGRWLLAGIGRWDQAWKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQ 265 + + + + +++IIF N+ L DIAL LA V+++ +I+ Sbjct: 228 AKKNNSKDWTVNFGIVVNKPYMTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIR 287 Query: 266 PACLPEKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNIS 325 CLPE ++ VTGWG + ++G P++LQE L I+ ++ C N + + Sbjct: 288 KICLPEAKMKLSENDNVVVTGWGTL--YMNGSFPVILQEDFLKIIDNKIC-----NASYA 340 Query: 326 KSKMVTRGTVC-GYNDQGKDACQGDSGGPLVC-ELNGTWVQVGIVSWGIGCGRKGYPGVY 383 S VT +C G+ DACQ DSGGPL + W VGIVSWG GCG+K PGVY Sbjct: 341 YSGFVTDTMLCAGFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVY 400 Query: 384 TEVSFYKKWI 393 T V+ Y+ WI Sbjct: 401 TRVTSYRNWI 410 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.135 0.445 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,801,993 Number of Sequences: 37866 Number of extensions: 1118459 Number of successful extensions: 11362 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 295 Number of HSP's successfully gapped in prelim test: 595 Number of HSP's that attempted gapping in prelim test: 7539 Number of HSP's gapped (non-prelim): 3124 length of query: 410 length of database: 18,247,518 effective HSP length: 105 effective length of query: 305 effective length of database: 14,271,588 effective search space: 4352834340 effective search space used: 4352834340 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.