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Search of human proteins with 239747891
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
(202 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 409 e-115
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 233 6e-62
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 206 8e-54
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 190 8e-49
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 181 5e-46
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 180 6e-46
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 170 9e-43
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 148 3e-36
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 145 2e-35
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 140 7e-34
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 140 7e-34
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 129 2e-30
gi|148746195 trichohyalin [Homo sapiens] 126 1e-29
gi|52426743 cisplatin resistance-associated overexpressed protei... 121 5e-28
gi|19923485 cisplatin resistance-associated overexpressed protei... 121 5e-28
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 111 4e-25
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 110 1e-24
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 108 3e-24
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 107 9e-24
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 104 4e-23
gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi... 104 4e-23
gi|213385278 TNF receptor-associated factor 3 interacting protei... 103 1e-22
gi|20070262 TNF receptor-associated factor 3 interacting protein... 103 1e-22
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 102 3e-22
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 100 8e-22
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 100 1e-21
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 100 1e-21
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 100 1e-21
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 98 5e-21
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 97 1e-20
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 409 bits (1051), Expect = e-115
Identities = 202/202 (100%), Positives = 202/202 (100%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK
Sbjct: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
Query: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR
Sbjct: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
Query: 121 ERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERK 180
ERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERK
Sbjct: 121 ERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERK 180
Query: 181 EKKKEEKRREDKKRKWGEGISP 202
EKKKEEKRREDKKRKWGEGISP
Sbjct: 181 EKKKEEKRREDKKRKWGEGISP 202
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 233 bits (595), Expect = 6e-62
Identities = 116/216 (53%), Positives = 166/216 (76%), Gaps = 16/216 (7%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHR----ERDRQTDREKERE 57
+RQRER R ++ E ER+RDR+R+RE + + + +R RDR + ERDR+ +++K RE
Sbjct: 76 DRQRERDRVREK-TEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRE 134
Query: 58 RQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRK 117
R+++R R+R+R+R+ E+E ERQ E+ R +R+ +T+RERD++R+++++RET+R+R+R R
Sbjct: 135 RERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRD 194
Query: 118 GGRERDKQTERERDRER----ERQRQRERERQRQRERKRETDRERQRWAER-------EE 166
+ER++QT+RERDR+R ERQR+ +RE +R+ +R+RE R+R R ER EE
Sbjct: 195 TEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEE 254
Query: 167 RKKERKKERKKERKEKKKEEKRREDKKRKWGEGISP 202
RKKERKKERKKERKEKKKEEKRREDKKRKWGEGISP
Sbjct: 255 RKKERKKERKKERKEKKKEEKRREDKKRKWGEGISP 290
Score = 50.1 bits (118), Expect = 1e-06
Identities = 31/91 (34%), Positives = 56/91 (61%), Gaps = 13/91 (14%)
Query: 114 RNRKGGRERDK-----QTERERDRERERQRQRERERQRQR-ERKRETDRERQRWAEREER 167
R R G +E + Q ++ D + RQRER+R R++ E++R+ DR+R +RE R
Sbjct: 51 RGRLGSQESPRSWGLGQAHKDADGD---DRQRERDRVREKTEKERDRDRKR----DRERR 103
Query: 168 KKERKKERKKERKEKKKEEKRREDKKRKWGE 198
+KE++ R ++R+++ + E+ RE +K+K E
Sbjct: 104 RKEKETNRNRDREKQTEIERDREREKQKGRE 134
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 206 bits (525), Expect = 8e-54
Identities = 102/211 (48%), Positives = 159/211 (75%), Gaps = 17/211 (8%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQ----TDREKERE 57
ER+RE++ E +R E E ERD++RERE +R+ RQ++R R+ DR+ T+R++E E
Sbjct: 239 EREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETE 298
Query: 58 RQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRK 117
R++ER R+R+RERE R+ ER+RER+R+RER+R+T+R+R+K+R+R+RKR+T+ +RERNR+
Sbjct: 299 RKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQ 358
Query: 118 GGRERDKQTERERDRERERQRQ-----------RERERQRQRERKRETDRERQRWAERE- 165
GRE +Q ERER+RERER RQ R+R+RQ++RER+ E DR+ QR E++
Sbjct: 359 TGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQR 418
Query: 166 ERKKERKKERKKER-KEKKKEEKRREDKKRK 195
ER+K+R+ ER +ER +E++K++ R D++R+
Sbjct: 419 EREKDRESERGRERGREREKQKGRERDRERQ 449
Score = 203 bits (516), Expect = 9e-53
Identities = 110/227 (48%), Positives = 158/227 (69%), Gaps = 34/227 (14%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTEREN---RHRQRDRHRERDRQTDREKERER 58
E++RER+ + +R ++ E+ER+RQ+ERE +TERE R RQ D RER+RQ D EKERER
Sbjct: 102 EKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERER 161
Query: 59 QKERDRQRQRERETERETERQRERQRQRERKRQTDRE-----------RDKDRDRE---- 103
Q +R+RQRQ ER ++E ER++ RQ +RER+RQ ++E R+++R+RE
Sbjct: 162 QTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETE 221
Query: 104 --RKRETDRNRERNRKGGRERDKQTERER----------DRERERQRQRERERQRQRERK 151
RKR+TDR R+R RK RER+KQ ERER +RERER R R+R+R RQ+ER+
Sbjct: 222 TERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDR-RQKERE 280
Query: 152 RETDRERQRWAERE---ERKKERKKERKKERKEKKKEEKRREDKKRK 195
R+TDR+RQR ER+ ERK+ER++ER++ER+ +K E+ RE ++ +
Sbjct: 281 RQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERER 327
Score = 202 bits (515), Expect = 1e-52
Identities = 99/201 (49%), Positives = 148/201 (73%), Gaps = 4/201 (1%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
+R+R+R+ E +R KE ERE++RQ RE + +RE ++ DRH ER R+ +RE+E E + E
Sbjct: 164 DRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETE 223
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNR---ERNRKG 118
R RQ RER+ +R+TER+RE+Q +RER + + ERDK+R+RER R+ DR+R ER R+
Sbjct: 224 RKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQT 283
Query: 119 GRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKE 178
R+R ++TER+R+ ER+R+RQRERER+R+R RKRE +RER+R ER +R+ ER +E+++E
Sbjct: 284 DRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERER-QRETERDREKERE 342
Query: 179 RKEKKKEEKRREDKKRKWGEG 199
RK K++ E RE ++ EG
Sbjct: 343 RKRKRQTEMDRERNRQTGREG 363
Score = 200 bits (509), Expect = 6e-52
Identities = 103/207 (49%), Positives = 153/207 (73%), Gaps = 13/207 (6%)
Query: 2 ERQRERKRETDRGKETERERDRQR----ERENQTEREN---RHRQRDRHRERDRQTDREK 54
ER+RE + ET+R ++T+RERDRQR ERE Q ERE R +RD+ RER+R DR++
Sbjct: 213 ERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDR 272
Query: 55 ER---ERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRN 111
+R ER+++ DR+RQR E +RETER+RERQR+RER+R+ +R+R+++R+RER+RE R
Sbjct: 273 DRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRE 332
Query: 112 RERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKER 171
ER+R+ RER ++ + E DRER RQ RE RQ +RER+RE +R+RQ EREER+++R
Sbjct: 333 TERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDR 392
Query: 172 KKERKKERK---EKKKEEKRREDKKRK 195
++R+KER+ EK ++ +R +K+R+
Sbjct: 393 DRDRQKERERQTEKDRDGQRETEKQRE 419
Score = 198 bits (504), Expect = 2e-51
Identities = 109/228 (47%), Positives = 163/228 (71%), Gaps = 34/228 (14%)
Query: 2 ERQRERKRETDRGK-ETERERDRQRERENQTERE-----NRHRQRDRHRERDRQTDREKE 55
ER R+++RE R K +TERE DR+RER + +R +R RQRDR +ER+RQTDRE++
Sbjct: 55 ERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERD 114
Query: 56 RERQKERDRQRQRERETERETERQRERQ----RQRERKRQTDRERDKDRDRERKRETDRN 111
R+R+KER+RQ++RERETERE ER R+RQ R+RER+R ++ER++ DRER+R+T+RN
Sbjct: 115 RQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERN 174
Query: 112 R------ERNRKGGRERDKQTERE-----------RDRERERQRQRERERQRQ----RER 150
R E+NR+ RER++Q E+E R+RERER+ + E ER+RQ R+R
Sbjct: 175 RQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDR 234
Query: 151 KRETDRERQRWAERE---ERKKERKKERKKERKEKKKEEKRREDKKRK 195
+R+T+RER++ AERE ER+ ER KER++ER + ++R+++++R+
Sbjct: 235 QRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQ 282
Score = 197 bits (501), Expect = 5e-51
Identities = 96/194 (49%), Positives = 149/194 (76%), Gaps = 3/194 (1%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
R+RER+RET+ E +R+ DR+R+R+ +TERE R +Q +R R +R+T+R+KERER+++R
Sbjct: 210 RERERERETETETERKRQTDRERDRQRKTERE-REKQAERERASERETERDKERERERDR 268
Query: 63 DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRER 122
DR R R R+ ERE + R+RQR+ ER R+T+R+R++ R+RER+RE +R RER R+ RER
Sbjct: 269 DRDRDR-RQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERER 327
Query: 123 DKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAERE-ERKKERKKERKKERKE 181
++Q E ERDRE+ER+R+R+R+ + RER R+T RE +R AERE ER++ER ++ +ER+E
Sbjct: 328 ERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREE 387
Query: 182 KKKEEKRREDKKRK 195
++++ R K+R+
Sbjct: 388 RERDRDRDRQKERE 401
Score = 196 bits (498), Expect = 1e-50
Identities = 107/221 (48%), Positives = 159/221 (71%), Gaps = 24/221 (10%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTEREN-RHRQRDRHRERDRQTDR-EKERERQ 59
ER+R+ RE DR ++TERER++Q ERE +ERE R ++R+R R+RDR DR +KERERQ
Sbjct: 223 ERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQ 282
Query: 60 KERDRQR--QRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRK 117
+R RQR +R+RETER+ ERQRER+R+RER R+ +RER+++R+RER+RET+R+RE+ R+
Sbjct: 283 TDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERE 342
Query: 118 GGRERDKQTERERDR----ERERQRQRERERQRQRER-------KRETDRERQRWAERE- 165
R+R + +RER+R E RQ +RERER+R+R+R +RE DR+R R ERE
Sbjct: 343 RKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERER 402
Query: 166 --------ERKKERKKERKKERKEKKKEEKRREDKKRKWGE 198
+R+ E+++ER+K+R+ ++ E+ RE +K+K E
Sbjct: 403 QTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRE 443
Score = 178 bits (452), Expect = 2e-45
Identities = 82/185 (44%), Positives = 136/185 (73%), Gaps = 7/185 (3%)
Query: 18 ERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER--DRQRQRERETERE 75
+RER+RQ+ERE + E+ R+ DR RER R+ DR ++R+R +ER DR+++RER+T+RE
Sbjct: 53 DRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRE 112
Query: 76 TERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERE 135
+RQRE++R R+++R+ + ER+ +R R+R+ + R RER R +ER++QT+RER R+ E
Sbjct: 113 RDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTE 172
Query: 136 RQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERK-----EKKKEEKRRE 190
R RQ+ERER++ R+ +RE +R+R++ + E+R ER +ER++ER+ E+K++ R
Sbjct: 173 RNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRER 232
Query: 191 DKKRK 195
D++RK
Sbjct: 233 DRQRK 237
Score = 174 bits (441), Expect = 5e-44
Identities = 93/184 (50%), Positives = 134/184 (72%), Gaps = 20/184 (10%)
Query: 2 ERQRERKRE--TDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQ 59
ERQ +RKR+ T+R +ETER+R+RQRERE + ER NR R+R+R RER+R+ RE ER+R+
Sbjct: 280 ERQTDRKRQRRTERDRETERKRERQRERERERER-NRKRERERERERERERQRETERDRE 338
Query: 60 KERDRQRQRERETERETERQ----------RERQRQRERKRQT-----DRERDKDRDRER 104
KER+R+R+R+ E +RE RQ RER+R+RER RQ+ +RERD+DRDR++
Sbjct: 339 KERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQK 398
Query: 105 KRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAER 164
+RE R E++R G RE +KQ ERE+DRE ER R+R RER++Q+ R+R+ +R+ R A R
Sbjct: 399 ERE--RQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGR 456
Query: 165 EERK 168
+ ++
Sbjct: 457 QRKR 460
Score = 155 bits (393), Expect = 2e-38
Identities = 87/195 (44%), Positives = 121/195 (62%), Gaps = 8/195 (4%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERE-NRHRQRDRHRERDRQTDR------EK 54
ER+R RKRE +R +E ERER R+ ER+ + ERE R RQ + RER+RQT R E+
Sbjct: 310 ERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAER 369
Query: 55 ERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRER 114
ERER++ERDRQ RERE ERE +R R+RQ++RER+ + DR+ ++ +++R+RE DR ER
Sbjct: 370 ERERERERDRQSARERE-ERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESER 428
Query: 115 NRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKE 174
R+ GRER+KQ RERDRER+ RQ R+R+R R + + + + +
Sbjct: 429 GRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGI 488
Query: 175 RKKERKEKKKEEKRR 189
R K E K R
Sbjct: 489 RWKSSPEDPKAASTR 503
Score = 154 bits (390), Expect = 4e-38
Identities = 82/189 (43%), Positives = 130/189 (68%), Gaps = 17/189 (8%)
Query: 22 DRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRE 81
D R R E R H++ D ++ER RQKER+R+R++ R+TERET+R+RE
Sbjct: 25 DFSRRRPGSQESPRRRGLGQAHKDADGD---DRERNRQKERERRREK-RQTERETDRKRE 80
Query: 82 RQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQR--- 138
R+R+++R R+ DR R++ RDRE++RE +RER+R+ +ER++Q ERER+ ERE +R
Sbjct: 81 RRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRD 140
Query: 139 -----QRERERQR--QRERKRETDRERQRWAER---EERKKERKKERKKERKEKKKEEKR 188
QRERERQR ++ER+R+TDRERQR ER +ER++E+ ++ ++ER+ ++++E +
Sbjct: 141 RQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENK 200
Query: 189 REDKKRKWG 197
ED+ + G
Sbjct: 201 TEDRHSERG 209
Score = 122 bits (307), Expect = 2e-28
Identities = 63/154 (40%), Positives = 104/154 (67%), Gaps = 6/154 (3%)
Query: 51 DREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDR---ERDKDRDRERKRE 107
D + R +E R+R + + RER RQ+ER+R+ ++ ER+ DR RER+RE
Sbjct: 25 DFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRRE 84
Query: 108 TDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAERE-- 165
DR+R+R+R R+RD++ ERER +RER RQRE+ER RQ+ER+RET+RE +R +R+
Sbjct: 85 KDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTD 144
Query: 166 -ERKKERKKERKKERKEKKKEEKRREDKKRKWGE 198
+R++ER+++ +KER+ + E++R+ ++ + E
Sbjct: 145 GQRERERQRDAEKERERQTDRERQRQTERNRQKE 178
Score = 114 bits (285), Expect = 6e-26
Identities = 76/206 (36%), Positives = 107/206 (51%), Gaps = 20/206 (9%)
Query: 2 ERQRERKRETDRG--KETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQ 59
E RER R+T R ++ ERER+R+RER+ Q+ RE R+RDR R DR+KERERQ
Sbjct: 350 EMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDR------DRQKERERQ 403
Query: 60 KERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
E+DR QRE E +RE E+ RE +R RER R +RE+ K R+R+R+R+TDR R RK
Sbjct: 404 TEKDRDGQRETEKQREREKDRESERGRERGR--EREKQKGRERDRERQTDRQAGRQRKRS 461
Query: 120 R---ERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERK 176
+T R + + R R + + R W + + R R
Sbjct: 462 TLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGR- 520
Query: 177 KERKEKKKEEKRREDKKRKWGEGISP 202
++ E R +K+ + GEG P
Sbjct: 521 ------RRWEPRLGEKRGQGGEGRRP 540
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 190 bits (482), Expect = 8e-49
Identities = 100/205 (48%), Positives = 145/205 (70%), Gaps = 19/205 (9%)
Query: 1 MERQRERKRETDRGKETERE---RDRQRERENQTERENRHRQRDRHRERDRQTDREKERE 57
M+RQRER+RETDR ++ +E DR ER+ Q +RE R+R+RDR RER++QTDRE ER+
Sbjct: 17 MDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRE-RNRERDRDREREKQTDREGERQ 75
Query: 58 RQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRK 117
R++ERDR RQ RETER+R+++R+ +R +TDRER K ++RE +R DR RE+ ++
Sbjct: 76 RERERDRDRQ------RETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKE 129
Query: 118 GGRERDKQTERERDRERERQRQRERE-------RQRQRERKRETDRERQRWAEREERKKE 170
GRER QT+RE DRERERQ +RERE R RER+RE RER+R E +ER++
Sbjct: 130 MGRER--QTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERH 187
Query: 171 RKKERKKERKEKKKEEKRREDKKRK 195
ER+++R+ +K +++RE ++ +
Sbjct: 188 TDMERERQRETDRKRDRQRESERER 212
Score = 155 bits (393), Expect = 2e-38
Identities = 83/161 (51%), Positives = 115/161 (71%), Gaps = 13/161 (8%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERE-NRHRQRDRHRERDRQTDREKERERQK 60
+R RER+++TDR E +RER+R R+R+ +TERE ++ R+ DRH E DR+ ++KERE ++
Sbjct: 59 DRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMER 118
Query: 61 ERDRQRQ------RERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRER 114
RDR+R+ RER+T+RET+R+RERQ +RE R+T RER K DR R+RE +R RER
Sbjct: 119 VRDREREKQKEMGRERQTDRETDRERERQAERE--RETGRER-KTEDRHRERERERKRER 175
Query: 115 NRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETD 155
RK K+ ER D ERERQR+ +R+R RQRE +RE D
Sbjct: 176 ERK---RETKERERHTDMERERQRETDRKRDRQRESERERD 213
Score = 105 bits (261), Expect = 3e-23
Identities = 56/127 (44%), Positives = 89/127 (70%), Gaps = 11/127 (8%)
Query: 70 RETERETERQRERQRQRERKRQTDRERDKDRDRERK-RETDRNRERNRKGGRERDKQTER 128
R T ETE RQRER+R+TDRERD+ ++ + + R ++R+R+R+R+ RERD+ ER
Sbjct: 8 RHTHTETETM---DRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRER 64
Query: 129 ERDRERERQRQRERERQRQRERKRETDRERQRWAERE-----ERKKERKKERKKERKEKK 183
E+ +RE +RQRERER R +R+RET+RER + E + +R+++++KER+ ER +
Sbjct: 65 EKQTDREGERQRERERDR--DRQRETERERDKERETDRHTETDRERQKQKEREMERVRDR 122
Query: 184 KEEKRRE 190
+ EK++E
Sbjct: 123 EREKQKE 129
Score = 50.1 bits (118), Expect = 1e-06
Identities = 25/55 (45%), Positives = 36/55 (65%), Gaps = 2/55 (3%)
Query: 146 RQRERKRETDRERQRWAE--REERKKERKKERKKERKEKKKEEKRREDKKRKWGE 198
RQRER+RETDRER R E E+R ER ++R +ER ++ ++ RE + + GE
Sbjct: 19 RQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGE 73
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 181 bits (458), Expect = 5e-46
Identities = 88/191 (46%), Positives = 138/191 (72%), Gaps = 9/191 (4%)
Query: 5 RERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDR 64
RE + D K+ E E+ ++ + + E+E R R+R+R RER+R RER++ER+R
Sbjct: 279 REISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERER-------RERERERER 331
Query: 65 QRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDK 124
+R+RE+E ERE ER+R+R R R ++R DR+R++DRDR+R+R +DRN++R+R + RD+
Sbjct: 332 EREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDR 391
Query: 125 QTERERDRERERQRQRERERQRQRERKRETDRERQ--RWAEREERKKERKKERKKERKEK 182
+ ERER+RERER+R+RERER+R+RER+RE +RER+ + +REE +++ + RK ERK +
Sbjct: 392 EREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLR 451
Query: 183 KKEEKRREDKK 193
+KE +E K
Sbjct: 452 EKEAAYQERLK 462
Score = 179 bits (454), Expect = 1e-45
Identities = 91/207 (43%), Positives = 139/207 (67%), Gaps = 16/207 (7%)
Query: 3 RQRERKRETDRGK-ETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
R +K E ++GK E ER+ + RE + ERE +R+R RER+R+ +REKE+ER++E
Sbjct: 285 RDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERE 344
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
R+R R R+R ER+ +R RER R R+R+R +DR +D+ R RE+ R+ +R RER R+ RE
Sbjct: 345 RERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERE 404
Query: 122 RDKQTERERDRERERQRQRERERQRQRERKR-ETDRERQRWAEREERKK----------- 169
R+++ ERER+RERER+R+RERE+ ++R+R+ E D +R ER+ R+K
Sbjct: 405 REREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNW 464
Query: 170 ---ERKKERKKERKEKKKEEKRREDKK 193
ERKK R+ E++ +++EE+RRE K
Sbjct: 465 EIRERKKTREYEKEAEREEERRREMAK 491
Score = 173 bits (438), Expect = 1e-43
Identities = 82/184 (44%), Positives = 130/184 (70%), Gaps = 3/184 (1%)
Query: 15 KETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETER 74
+E + RD ++ E + ++ + RQ R+R+ +RE+ERER R+R+R+RERE ER
Sbjct: 279 REISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERER---RERERERERERER 335
Query: 75 ETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRER 134
E E++RER+R+R+R R +ERD+DRDRER R+ DR R +R R R ++ R+R+RER
Sbjct: 336 EKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERER 395
Query: 135 ERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKR 194
ER+R+RERER+R+RER+RE +RER+R ERE+ KK ++E +++ E++K E++ +K+
Sbjct: 396 EREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEA 455
Query: 195 KWGE 198
+ E
Sbjct: 456 AYQE 459
Score = 172 bits (435), Expect = 2e-43
Identities = 88/194 (45%), Positives = 138/194 (71%), Gaps = 7/194 (3%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
ER+RER+RE +R +E ERER+R+RERE + ERE R R+RDR R+R ++ DR+++RER ++
Sbjct: 311 ERERERERERER-REREREREREREREKEKERE-RERERDRDRDRTKERDRDRDRERDRD 368
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
RDR+R +R +R R++ R R+RER+R+ +RER+++R+RER+RE +R RER R+ RE
Sbjct: 369 RDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERERE--RE 426
Query: 122 RDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKE 181
+DK+ +RE D E +R R+ +R+ K +ER + E ERKK R+ E++ ER+E
Sbjct: 427 KDKKRDREEDEEDAYER---RKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREE 483
Query: 182 KKKEEKRREDKKRK 195
+++ E +E K+ K
Sbjct: 484 ERRREMAKEAKRLK 497
Score = 171 bits (432), Expect = 5e-43
Identities = 86/190 (45%), Positives = 135/190 (71%), Gaps = 8/190 (4%)
Query: 10 ETDRGKETERERDRQRERENQTERENRHRQRDRHR-ERDRQTDREKERERQKERDRQRQR 68
E D+ RE + R+ + E E ++++R E++R RE+ERER++ER+R R+R
Sbjct: 270 EEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKER---RERERERERERER-RER 325
Query: 69 ERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTER 128
ERE ERE ER++E++R+RER+R DR+R K+RDR+R RE DR+R+R R R +D+ R
Sbjct: 326 EREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSR 385
Query: 129 ERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKR 188
E+ R+RER+R+RERER+R+RER+RE +RER+R ER++ER+K++K++R+E +++
Sbjct: 386 EKSRDRERERERERERERERERERERERERER---EREREREREKDKKRDREEDEEDAYE 442
Query: 189 REDKKRKWGE 198
R +RK E
Sbjct: 443 RRKLERKLRE 452
Score = 158 bits (400), Expect = 3e-39
Identities = 88/229 (38%), Positives = 146/229 (63%), Gaps = 31/229 (13%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERE-NRHRQRDRHRERDRQTDREKER---- 56
ER+RER+RE ++ KE ERER+R R+R+ ER+ +R R+RDR R+R+R +DR K+R
Sbjct: 326 EREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSR 385
Query: 57 ------ERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRE---RKRE 107
ER++ER+R+R+RERE ERE ER+RER+R+RER+R+ D++RD++ D E +R+
Sbjct: 386 EKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRK 445
Query: 108 TDRNRERNRKGGRERDKQTE-RERDRERERQRQRERERQRQRERKRETDRERQ------- 159
+R +ER K E RER + RE +++ ERE +R+RE +E R ++
Sbjct: 446 LERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDD 505
Query: 160 --------RWAEREERKKERKKERKKERKEKKKEEKRRED-KKRKWGEG 199
R + ++R ++R+KE + + +++K+E++ E+ ++R EG
Sbjct: 506 DRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEG 554
Score = 143 bits (360), Expect = 1e-34
Identities = 75/173 (43%), Positives = 123/173 (71%), Gaps = 5/173 (2%)
Query: 25 RERENQTERENRHRQR-DRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQ 83
+E N E E R R + R T ++ E E+ K ++++RQ + RE ER+RER+
Sbjct: 261 KEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGK-KEKERQEIEKERRERERERERE 319
Query: 84 RQ-RERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRER 142
R+ RER+R+ +RER++++++ER+RE +R+R+R+R R+RD+ ER+RDR+RER R +
Sbjct: 320 RERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNK 379
Query: 143 ERQRQRERKRETDRERQRWAERE-ERKKERKKERKKERKEKKKEEKRREDKKR 194
+R R RE+ R+ +RER+R ERE ER++ER++ER++ER E+++E +R +DKKR
Sbjct: 380 DRSRSREKSRDRERERERERERERERERERERERERER-EREREREREKDKKR 431
Score = 121 bits (303), Expect = 5e-28
Identities = 73/213 (34%), Positives = 127/213 (59%), Gaps = 22/213 (10%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK-E 61
R RER+RE +R +E ERER+R+RERE + ERE R R+R++ ++RDR+ D E ER+K E
Sbjct: 389 RDRERERERERERERERERERERERERERERE-REREREKDKKRDREEDEEDAYERRKLE 447
Query: 62 RD-----------------RQRQRERETERETERQRERQRQ--RERKRQTDRERDKDRDR 102
R R+R++ RE E+E ER+ ER+R+ +E KR + D D DR
Sbjct: 448 RKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDR 507
Query: 103 ERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWA 162
+ + + + R RE++ + + ERDR+RE++ E ++ E + D E QR
Sbjct: 508 DDPKYYRGSALQKRLRDREKEMEAD-ERDRKREKEELEEIRQRLLAEGHPDPDAELQRME 566
Query: 163 EREERKKERKKERKKERKEKKKEEKRREDKKRK 195
+ ER+++ + +++ E +E+++E++ +E+K+ +
Sbjct: 567 QEAERRRQPQIKQEPESEEEEEEKQEKEEKREE 599
Score = 95.5 bits (236), Expect = 3e-20
Identities = 50/141 (35%), Positives = 92/141 (65%), Gaps = 12/141 (8%)
Query: 59 QKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKG 118
+ E D++ RE + + ++ + ++ +K + +E +K+R RER+RE +R RER
Sbjct: 268 EMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKER-RERERERERERER---- 322
Query: 119 GRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAERE-ERKKERKKERKK 177
R+++ ERER+RERE++++RERER+R R+R R +R+R R ER+ +R +ER +R K
Sbjct: 323 ---REREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNK 379
Query: 178 ER---KEKKKEEKRREDKKRK 195
+R +EK ++ +R +++R+
Sbjct: 380 DRSRSREKSRDRERERERERE 400
Score = 84.0 bits (206), Expect = 8e-17
Identities = 56/185 (30%), Positives = 104/185 (56%), Gaps = 28/185 (15%)
Query: 27 RENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQ-------------RQRERETE 73
RE +E ++ D H R+K++E++++ R+ ++ E
Sbjct: 216 REYSSELNAPSQESDSH-------PRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIE 268
Query: 74 RETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRE 133
E +++ R+ + R T ++ ++++ ++ K + +ER RER+++ ERER RE
Sbjct: 269 MEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRE---RERERERERER-RE 324
Query: 134 RERQRQRERER--QRQRERKRETDRERQRWAERE-ERKKERKKERKKER-KEKKKEEKRR 189
RER+R+RERER +++RER+RE DR+R R ER+ +R +ER ++R +ER ++ K+ R
Sbjct: 325 REREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRS 384
Query: 190 EDKKR 194
+K R
Sbjct: 385 REKSR 389
Score = 50.1 bits (118), Expect = 1e-06
Identities = 31/98 (31%), Positives = 56/98 (57%), Gaps = 7/98 (7%)
Query: 7 RKRETDRGKETER-ERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQ 65
+KR DR KE E ERDR+RE+E E R + H + D + R ++E +R+
Sbjct: 519 QKRLRDREKEMEADERDRKREKEELEEIRQR-LLAEGHPDPDAELQR-----MEQEAERR 572
Query: 66 RQRERETERETERQRERQRQRERKRQTDRERDKDRDRE 103
RQ + + E E+E + E ++++E KR+ E +++ +++
Sbjct: 573 RQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQK 610
Score = 39.3 bits (90), Expect = 0.002
Identities = 24/83 (28%), Positives = 43/83 (51%), Gaps = 8/83 (9%)
Query: 4 QRERKRETDRGKETERERDRQR---ERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
+R+RKRE + E E RQR E + E + +++ R R Q +E E E ++
Sbjct: 533 ERDRKREKE-----ELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEE 587
Query: 61 ERDRQRQRERETERETERQRERQ 83
E ++++ +RE E E + E++
Sbjct: 588 EEKQEKEEKREEPMEEEEEPEQK 610
Score = 29.3 bits (64), Expect = 2.4
Identities = 11/46 (23%), Positives = 26/46 (56%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRER 46
ME++ ER+R+ +E E E + + ++E + +RE + + ++
Sbjct: 565 MEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQK 610
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 180 bits (457), Expect = 6e-46
Identities = 94/204 (46%), Positives = 144/204 (70%), Gaps = 7/204 (3%)
Query: 2 ERQRERKRETD-RGKETERERDRQRERENQTERENRHRQR--DRHRERDRQTDREKERER 58
ER R RE D R R + R E E RE R R DR ER R+ DRE+ER+R
Sbjct: 628 ERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDR 687
Query: 59 QKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKG 118
++ER+R+R+R+RE E+E E +RER R+RER+R+ +R+R++DRDR+ RE +R RER+R+
Sbjct: 688 ERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREK 747
Query: 119 GRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQR-WAEREERKKERKKERKK 177
RER+++ ERER+RERER+R+RERER+R+R R+R+ +RERQR W ++++ + +R+++R++
Sbjct: 748 ERERERE-ERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREE 806
Query: 178 ERKEKKKEE--KRREDKKRKWGEG 199
R+++ + R+ KKR EG
Sbjct: 807 IREDRNPRDGHDERKSKKRYRNEG 830
Score = 163 bits (413), Expect = 8e-41
Identities = 83/187 (44%), Positives = 128/187 (68%), Gaps = 12/187 (6%)
Query: 21 RDRQRERENQTERENRHRQRD-----RHRERDRQTDREKERE------RQKERDRQRQRE 69
R ER+ ER+NR + RD RH ERDR+ +RE+++ Q D + E
Sbjct: 599 RSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDE 658
Query: 70 RETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERE 129
R ER +R +R+ +R R+R +RERD++R+RER+RE DR RE+ R+ RER ++ ERE
Sbjct: 659 RREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERERE 718
Query: 130 RDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKER-KEKKKEEKR 188
R++ER+R+R R+R+ R+RER+RE DRE++R EREER++ER++ER++ER +E+++E R
Sbjct: 719 REKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERAR 778
Query: 189 REDKKRK 195
DK+R+
Sbjct: 779 ERDKERE 785
Score = 161 bits (407), Expect = 4e-40
Identities = 87/201 (43%), Positives = 142/201 (70%), Gaps = 8/201 (3%)
Query: 2 ERQRERKRET-DRGKETERERDR-QRERENQTERENRHRQRDRHRERDRQTDREKERE-R 58
ER R +R+ D+ +++ ER +R+R + ER+ R RH+ R+ + +R++ RE R
Sbjct: 604 ERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREER 663
Query: 59 QKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKG 118
+ +R R+ ER ER+ ER+R+R+R+RER+R+ DRER+K+R+ ER+R +R RER ++
Sbjct: 664 RVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKER 723
Query: 119 GRERDKQTERERDRERERQRQRERERQRQR-ERKRETDRERQRWAEREERKKERKKERKK 177
RERD+ + +R+RERER+R RE+ER+R+R ER+RE +RER+R ER ER++ER +ER K
Sbjct: 724 DRERDRDRDHDRERERERERDREKEREREREERERERERERERERER-ERERERARERDK 782
Query: 178 ERKEKK---KEEKRREDKKRK 195
ER+ ++ ++K R+D++ K
Sbjct: 783 ERERQRDWEDKDKGRDDRREK 803
Score = 159 bits (403), Expect = 1e-39
Identities = 88/204 (43%), Positives = 142/204 (69%), Gaps = 12/204 (5%)
Query: 5 RERKRETD-RGKETERERDRQRERENQTERENRHRQRDRHRERD-RQTDREKERERQKER 62
R++ R++ + ER+R RER+ + RH+ R+ ERD R+ +R +R +
Sbjct: 614 RDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRD 673
Query: 63 DRQRQRERETERETERQRERQRQRERKRQTDR--ERDKDRDRERKRETDRNRERNRKGGR 120
+R R+R+RE ER+ ER+RER+R+R+R+R+ +R ER++ R+RER+RE +R+RER+R
Sbjct: 674 ERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDH 733
Query: 121 ERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAER-EERKKERKKERKKER 179
+R+++ ERERDRE+ER+R+RE ER+R+RER+RE +RER+R ER ER KER+++R E
Sbjct: 734 DRERERERERDREKERERERE-ERERERERERERERERERERERARERDKERERQRDWED 792
Query: 180 KEKKKEEKR------REDKKRKWG 197
K+K ++++R RED+ + G
Sbjct: 793 KDKGRDDRREKREEIREDRNPRDG 816
Score = 155 bits (393), Expect = 2e-38
Identities = 84/190 (44%), Positives = 129/190 (67%), Gaps = 12/190 (6%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
+R+ ER RE DR ERERDR+RERE + ER+ R+R++ RE +R+ RE+ERER+KE
Sbjct: 670 DRRDERARERDR----ERERDRERERERERERD---REREKERELERERAREREREREKE 722
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
RDR+R R+R+ +RE ER+RER R++ER+R+ + +++R+RER+RE +R RER R+ RE
Sbjct: 723 RDRERDRDRDHDRERERERERDREKERERERE---ERERERERERERERERERERERARE 779
Query: 122 RDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKE 181
RDK+ ER+RD E ++ + R+ +R+ +RE RE R ER+ +K+ R + R+
Sbjct: 780 RDKERERQRDWE-DKDKGRD-DRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQS 837
Query: 182 KKKEEKRRED 191
K+ + D
Sbjct: 838 PKRRREHSPD 847
Score = 148 bits (374), Expect = 3e-36
Identities = 90/250 (36%), Positives = 145/250 (58%), Gaps = 55/250 (22%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTEREN-----RHRQRDRHRERDRQTDREKER 56
ER RER+R+ +R +E ERERDR+RE+E + ERE R R+++R RERDR D ++ER
Sbjct: 678 ERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRER 737
Query: 57 ERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETD-RNRERN 115
ER++ERDR+++RERE E E ER+RER+R+RER+R+ +RER ++RD+ER+R+ D ++++
Sbjct: 738 ERERERDREKERERERE-ERERERERERERERERERERERARERDKERERQRDWEDKDKG 796
Query: 116 RKGGRERDKQTERER------DRERERQRQR-------ERERQRQRERKRETD------- 155
R RE+ ++ +R D + ++R R + +R+RE ++D
Sbjct: 797 RDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDD 856
Query: 156 --------------------------RERQ-RWAEREERKKERKKERKKERKEKKKEEKR 188
+RQ RW E E+RK ERK+ ++ +++ KE+
Sbjct: 857 KNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKE-EDRKPERKESSRRYEEQELKEKVS 915
Query: 189 REDKKRKWGE 198
DK+R+ E
Sbjct: 916 SVDKQREQTE 925
Score = 115 bits (289), Expect = 2e-26
Identities = 90/287 (31%), Positives = 134/287 (46%), Gaps = 89/287 (31%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERE---NRHRQRDRHRERDRQTDREKERER 58
ER+RER RE ++ +E ERER R+RERE + ER+ +R R DR RER+R+ DREKERER
Sbjct: 692 ERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERER 751
Query: 59 QKE---RDRQRQRERETERETERQRERQRQRERKRQTDRE-----RDKDRDRERKRETD- 109
++E R+R+R+RERE ERE ER+R R+R +ER+RQ D E RD R++ + D
Sbjct: 752 EREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDR 811
Query: 110 ---------RNRERNRKGGRERDKQTERER-------------DRERERQRQRERERQRQ 147
++++R R G +Q+ + R D + E+ R + + Q
Sbjct: 812 NPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQ 871
Query: 148 RERKRE----TDRERQRWAEREERKKERKKERKK-------------------------- 177
R T+ + RW E E+RK ERK+ ++
Sbjct: 872 ESRSLSPSHLTEDRQGRWKE-EDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESS 930
Query: 178 ------------------------ERKEKKKEEKRREDKKRKWGEGI 200
E K+K K +K+ KK++ GI
Sbjct: 931 RMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGI 977
Score = 91.7 bits (226), Expect = 4e-19
Identities = 66/194 (34%), Positives = 95/194 (48%), Gaps = 17/194 (8%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
+E ERK D+ K E R +R++ +R + R+ ++ R+R +
Sbjct: 1241 LEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQ 1300
Query: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
ERDR E RER+R+R RQ + +RD D+D R R+ DR RER R+ R
Sbjct: 1301 ERDRY-----------EHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERE--R 1347
Query: 121 ERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKE-- 178
ERDK+ R+ DRERER ER R R+R R + + +R E K E + ER E
Sbjct: 1348 ERDKR--RDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLEST 1405
Query: 179 RKEKKKEEKRREDK 192
++ +K R DK
Sbjct: 1406 SRDSLALDKERMDK 1419
Score = 84.0 bits (206), Expect = 8e-17
Identities = 60/194 (30%), Positives = 101/194 (52%), Gaps = 12/194 (6%)
Query: 4 QRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHR-ERDRQTDREKERERQKER 62
Q RKR G R+R++ + E ER++R Q R R +DR+ R R
Sbjct: 1221 QSGRKRVLHSGS---RDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRR 1277
Query: 63 DRQRQRERETERETERQRERQRQRERKR-QTDRERDKDRDRERKRETDRNRERNRKGGRE 121
+ +R+ + R R +ER R + DRER+++R R+RE DR+ +++ R+
Sbjct: 1278 SSP-ESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRD 1336
Query: 122 RDKQTERERDRERERQRQRERERQRQR----ERKRETDRERQRWAEREERKKERKKERKK 177
RD+ RER+RERER ++R+ +R+R+R +R+ DR+R R E + + ++ E K
Sbjct: 1337 RDRL--RERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKL 1394
Query: 178 ERKEKKKEEKRRED 191
E + ++ E D
Sbjct: 1395 EGEHERDLESTSRD 1408
Score = 80.5 bits (197), Expect = 9e-16
Identities = 62/216 (28%), Positives = 100/216 (46%), Gaps = 32/216 (14%)
Query: 2 ERQRERKRETDRGK-ETERE----------RDRQRERENQTERENRHRQRDRHRERDRQT 50
+RQ R + R E++R+ RDR +ER+ +R R+R+R R R+
Sbjct: 1266 DRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRY--EHDRERERERRDTRQREW 1323
Query: 51 DREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDR 110
DR+ +++ + RDR R RERE ERE +++R+ R+RER ERD+DRDR+R E+
Sbjct: 1324 DRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFES-- 1381
Query: 111 NRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRER-QRWAEREERKK 169
Q E + E + + + ER+ + D+ER + + +
Sbjct: 1382 -------------SQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFE 1428
Query: 170 ERKKERKKERKEKKKEEKRREDKKRKW---GEGISP 202
E K + E E +E + +D GEG P
Sbjct: 1429 ETNKSERTESLEAGDDESKLDDAHSLGSGAGEGYEP 1464
Score = 75.1 bits (183), Expect = 4e-14
Identities = 72/292 (24%), Positives = 111/292 (38%), Gaps = 101/292 (34%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
ER+ E+ + + R +RE R+R + + +R RD RD + R+ R+ ++
Sbjct: 433 EREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKES 492
Query: 62 RD------------------RQRQRERETERETERQRERQRQRERKRQTD-RERDKDRDR 102
RD R R+ +T E R R RE +T+ R ++ R
Sbjct: 493 RDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESR 552
Query: 103 ERKRETDRNRERNR------KGGR------------------------------------ 120
R R R R KG R
Sbjct: 553 SEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERD 612
Query: 121 ---------------ERDKQTERERDR---------------ERERQRQRER-------- 142
ERD++ RERD+ ER+ +R+ R
Sbjct: 613 NRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRR 672
Query: 143 -ERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKK 193
ER R+R+R+RE DRER+R ER ER +ER+KER+ ER+ ++ E+ RE ++
Sbjct: 673 DERARERDRERERDRERERERER-ERDREREKERELERERAREREREREKER 723
Score = 70.9 bits (172), Expect = 7e-13
Identities = 53/195 (27%), Positives = 93/195 (47%), Gaps = 6/195 (3%)
Query: 5 RERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDR 64
R + T + R ++Q+ R+ R RE+ + + ER+ + ++ +
Sbjct: 1196 RSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLK 1255
Query: 65 QRQRERETERETERQRERQRQR---ERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
+ + R T + + R +R E RQ R+R +E DR E +R+ RE
Sbjct: 1256 RGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRY-EHDRERERE 1314
Query: 122 RDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAERE-ERKKERKKERKKER- 179
R +RE DR+ ++ R R+R R RER+RE +R+++R +RE ER ER ++R
Sbjct: 1315 RRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRD 1374
Query: 180 KEKKKEEKRREDKKR 194
+++ E + E KR
Sbjct: 1375 RDRTFESSQIESVKR 1389
Score = 70.5 bits (171), Expect = 9e-13
Identities = 50/186 (26%), Positives = 84/186 (45%), Gaps = 11/186 (5%)
Query: 6 ERKRETDRGKETERERDRQRERENQTERENRHRQRD-----RHRERDRQTDREKERERQK 60
+RK+ R + RE+ R + RH +R+ R RE+D + +RE E+++
Sbjct: 383 QRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSS 442
Query: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRE-RNRKGG 119
RD + RE R+ R+ + +RE + D RD R+ R+T +R+ R+ +
Sbjct: 443 SRDHRDDREPRDGRDRRDARDTRDRRELRDSRDM-RDSREMRDYSRDTKESRDPRDSRST 501
Query: 120 RERDKQTERE-RDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKE 178
R+ +RE RD R+ E R R RE E R R E + E + E + +
Sbjct: 502 RDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLRE---ESSRTEIRNESRNESRSEIRND 558
Query: 179 RKEKKK 184
R + +
Sbjct: 559 RMGRSR 564
Score = 68.6 bits (166), Expect = 4e-12
Identities = 58/232 (25%), Positives = 98/232 (42%), Gaps = 42/232 (18%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKE--RERQ 59
+R+ ER+ +T RGK +RE+D + ERE + ++ + RD RD + R+ R+R+
Sbjct: 411 DRRHERREDT-RGKR-DREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRR 468
Query: 60 KERDRQRQRE----RETERETERQRERQRQRERKRQTDRERDKDRDRERKRET--DRNRE 113
+ RD + R+ R+ R+T+ R+ + R + D + RD RK +T + +R
Sbjct: 469 ELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRS 528
Query: 114 RNRKGGRERDKQTE-RERDRERERQRQRERERQRQRER---------------------- 150
R RE +TE R R R R R R R
Sbjct: 529 YGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSS 588
Query: 151 ---------KRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKK 193
R + ER R+ ER+ R + R ++ E+ + + R D++
Sbjct: 589 NSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQR 640
Score = 68.2 bits (165), Expect = 5e-12
Identities = 54/201 (26%), Positives = 96/201 (47%), Gaps = 25/201 (12%)
Query: 6 ERKRETDRGKETERERDRQRERENQTERENRHRQRDR---------HRERDRQTDREKER 56
E T + + D++R + R NR R HR D Q+ R++
Sbjct: 1169 ETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVL 1228
Query: 57 ERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKR---ETDRNRE 113
RDR++ + E E + + ++ ++ E R T +R R +R E+DR +
Sbjct: 1229 H-SGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDR-QV 1286
Query: 114 RNRKGGRERDKQTERERDRERERQR-QRERERQRQRE--RKRETDRERQR-WAEREERKK 169
+R G + RDR +ER R + +RER+R+R R+RE DR+ + W +R +
Sbjct: 1287 HSRSGSFD-------SRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDR 1339
Query: 170 ERKKERKKERKEKKKEEKRRE 190
R++ER++ER +++ ++ RE
Sbjct: 1340 LRERERERERDKRRDLDRERE 1360
Score = 59.7 bits (143), Expect = 2e-09
Identities = 45/201 (22%), Positives = 88/201 (43%), Gaps = 16/201 (7%)
Query: 2 ERQRERKRE-TDRGKETERERDRQRERENQTERENRHRQ--RDRHRERDRQTDREKERER 58
+R E+ R+ DRG++ ER+R++ R++ T +H RH Q+ +R
Sbjct: 288 DRIEEKTRDGKDRGRDFERQREK-RDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHS 346
Query: 59 QKERDRQRQRERETERETERQRERQ---------RQRERKRQTDRERDKDRDRERKRETD 109
R R+R +R R +RK+ R R R++ R
Sbjct: 347 PSPR-RKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHER 405
Query: 110 RNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKK 169
++ +R+ ER + T +RDRE++ + +RE E+ + R DRE + +R + +
Sbjct: 406 TSQSHDRR--HERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARD 463
Query: 170 ERKKERKKERKEKKKEEKRRE 190
R + ++ ++ + + R+
Sbjct: 464 TRDRRELRDSRDMRDSREMRD 484
Score = 59.7 bits (143), Expect = 2e-09
Identities = 47/173 (27%), Positives = 77/173 (44%), Gaps = 12/173 (6%)
Query: 36 RHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRE 95
R + RHR R+ R + DR+ +R +T + R RE+ + ER+ + D+
Sbjct: 384 RKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGK--RDREKDSREEREYEQDQS 441
Query: 96 RDKDR--DRERKRETDRNRERNRKGGRE----RDKQTERE-RDRERERQRQRE-RERQRQ 147
+D DRE + DR R+ + RE RD + RE RD R+ + R+ R+ +
Sbjct: 442 SSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRST 501
Query: 148 RERKRETDRERQRWAEREERKKERKKE--RKKERKEKKKEEKRREDKKRKWGE 198
R+ DRE + +E+ E + R R+E + E R E + E
Sbjct: 502 RDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSE 554
Score = 55.5 bits (132), Expect = 3e-08
Identities = 42/163 (25%), Positives = 63/163 (38%), Gaps = 12/163 (7%)
Query: 39 QRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDK 98
QR + R R REK R + + R E +T +R+R E+ + +RE ++
Sbjct: 383 QRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDR----EKDSREEREYEQ 438
Query: 99 DRDRERKRETDRNRERNRKGGRERDKQTERE-------RDRERERQRQRERERQRQRERK 151
D+ R DR R RD + RE RD R R+ + R
Sbjct: 439 DQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDS 498
Query: 152 RETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKR 194
R T R+ + +RE R RK++ E RE+ R
Sbjct: 499 RST-RDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSR 540
Score = 50.8 bits (120), Expect = 8e-07
Identities = 41/203 (20%), Positives = 90/203 (44%), Gaps = 21/203 (10%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
+R+RE ++D + + ++ R + H DRQ R KE +R+ E
Sbjct: 839 KRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQ-GRWKEEDRKPE 897
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDR--DRERKRETD----RNRERN 115
R +E+ R+ E Q +E+ D++R++ + R R D E
Sbjct: 898 R-----------KESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDR 946
Query: 116 RKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKK---ERK 172
R D+ ++ + +++ ++++E + +R T + Q ++ ++ +KK E+K
Sbjct: 947 ETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKK 1006
Query: 173 KERKKERKEKKKEEKRREDKKRK 195
+++ K + EE ++ KK++
Sbjct: 1007 RKKSKGDSDISDEEAAQQSKKKR 1029
Score = 40.0 bits (92), Expect = 0.001
Identities = 35/162 (21%), Positives = 65/162 (40%), Gaps = 7/162 (4%)
Query: 33 RENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQT 92
R + R RER + ++ + E QK + E R RE++ + K +T
Sbjct: 75 RRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERT 134
Query: 93 DRERDKDRDRERKRETDRNRERNRKGGRERDKQTERER-DRERERQRQRERERQRQRERK 151
+++ + E R+ N + N E + +R++ RE + Q E++ + K
Sbjct: 135 PESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIK 194
Query: 152 RETDRERQRW------AEREERKKERKKERKKERKEKKKEEK 187
+E E R + R+ K ++K K KK+ K
Sbjct: 195 KEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRK 236
Score = 39.7 bits (91), Expect = 0.002
Identities = 37/172 (21%), Positives = 72/172 (41%), Gaps = 18/172 (10%)
Query: 34 ENRHRQRDRHRERDRQ-TDREKERERQKERDRQRQRERETERETERQR---ERQRQRERK 89
+ +++ +DR E+ R DR ++ ERQ+E+ R + R T + R +
Sbjct: 281 KEKYKVKDRIEEKTRDGKDRGRDFERQREK---RDKPRSTSPAGQHHSPISSRHHSSSSQ 337
Query: 90 RQTDRERDKDRDRERKRETDRNRERNRKGGRERD---------KQTERERDRERERQRQR 140
+ +R R RKR + +R R +R++ R R R
Sbjct: 338 SGSSIQRHSPSPR-RKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMR 396
Query: 141 ERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDK 192
E+ R + DR +R E K++R+K+ ++ER+ ++ + R+ +
Sbjct: 397 EKGRHDHERTSQSHDRRHER-REDTRGKRDREKDSREEREYEQDQSSSRDHR 447
Score = 37.7 bits (86), Expect = 0.007
Identities = 28/158 (17%), Positives = 63/158 (39%), Gaps = 14/158 (8%)
Query: 52 REKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRD--RERKRETD 109
R ER R+R + + ++ + E +++ + ++++ R R ++++ + K T
Sbjct: 76 RSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERTP 135
Query: 110 RNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKK 169
+ E N + RD + + + + E +RQ+ + + ++E E KK
Sbjct: 136 ESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKK 195
Query: 170 ERKKE------------RKKERKEKKKEEKRREDKKRK 195
E E RK + K+K + +K
Sbjct: 196 EVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKK 233
Score = 33.1 bits (74), Expect = 0.16
Identities = 43/206 (20%), Positives = 84/206 (40%), Gaps = 45/206 (21%)
Query: 8 KRETDRGKETERERDR-QRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQR 66
++E+ RG+ E+E + +ER ++E EN + +R + + + E E RQ+
Sbjct: 113 RKESSRGRHREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQK 172
Query: 67 -QRE-RETERETERQRE-----------------------RQRQRERKRQTDRERDKDRD 101
QRE + E+E +RE R+ + KR++ +
Sbjct: 173 IQRELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASK 232
Query: 102 RERKRETDRN----RERNRKGGRERDKQTERER------------DRERERQRQRERERQ 145
++RK + ++RN K + + K + +E+ + ++R +
Sbjct: 233 KDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEE 292
Query: 146 RQRERKRETDRERQRWAEREERKKER 171
+ R+ K DR R +RE+R K R
Sbjct: 293 KTRDGK---DRGRDFERQREKRDKPR 315
Score = 30.8 bits (68), Expect = 0.82
Identities = 21/78 (26%), Positives = 34/78 (43%), Gaps = 1/78 (1%)
Query: 115 NRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKE 174
N + ER RER + + + E +++ E +E R RE+ + KE
Sbjct: 73 NYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKE 132
Query: 175 RKKERKEKKKE-EKRRED 191
R E +E+ E E R+D
Sbjct: 133 RTPESEEENVEWETNRDD 150
>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
Length = 285
Score = 170 bits (430), Expect = 9e-43
Identities = 95/190 (50%), Positives = 138/190 (72%), Gaps = 20/190 (10%)
Query: 19 RERDRQRERENQTER-ENRHRQRDRHRERDRQTDREKERERQKERDRQRQRER----ETE 73
RER+RQRERE Q +R + RHR++DR E+DR R+++RERQ+ RDR R+RER + E
Sbjct: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
Query: 74 RETERQRERQRQRERKRQTDRERDKDR----DRERKRETDRNRERNRKGGRERDKQTERE 129
ETERQ ER+RQR+RKR+ DRER + R D++R+ ET+++R+R R+ G +TER
Sbjct: 118 TETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMG-----ETERY 172
Query: 130 RDRERERQRQRE----RERQRQRERK-RETDRERQRWAEREE-RKKERKKERKKERKEKK 183
RDRERERQ+QRE R+R+RQRE++ RE DR+RQ+ E++ R++E ++R KER ++
Sbjct: 173 RDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRER 232
Query: 184 KEEKRREDKK 193
+ EK R+ +K
Sbjct: 233 QREKDRDRQK 242
Score = 166 bits (419), Expect = 2e-41
Identities = 99/206 (48%), Positives = 135/206 (65%), Gaps = 37/206 (17%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
ERQRER+R+ R KE RE+DR+ E++ R RQR R RER R DR+++RER +
Sbjct: 61 ERQRERERQRKRAKERHREKDREIEKD-------RDRQRKRDRERQRWRDRDRKRERWGD 113
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDR----DRERKRETDRNRERNRK 117
RDR E ETERQ ER+RQR+RKR+ DRER + R D++R+ ET+++R+R R+
Sbjct: 114 RDR--------ETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDRERE 165
Query: 118 GGRERDKQTERERDRERERQRQRERERQRQRERKRE-TDRERQRWAEREERKKERKKERK 176
G +TER RDRERERQ+QRE R R RER+RE DRER R +R+KER+K+R
Sbjct: 166 MG-----ETERYRDRERERQKQRETRRDRDRERQREKEDRERDR-----DRQKEREKDRY 215
Query: 177 KER-------KEKKKEEKRREDKKRK 195
+ER KE+ +E +R +D+ R+
Sbjct: 216 RERETGRDRDKERDRERQREKDRDRQ 241
Score = 147 bits (370), Expect = 8e-36
Identities = 73/159 (45%), Positives = 120/159 (75%), Gaps = 11/159 (6%)
Query: 1 MERQRERKRETDRGKETERERDRQRER------ENQTER-ENRHRQRDRHRERDRQTDRE 53
+E+ R+R+R+ DR ++ R+RDR+RER E +TER E R RQRDR RE+DR+ R+
Sbjct: 84 IEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQ 143
Query: 54 KERERQKERDRQRQRERETER---ETERQRERQRQRERKRQTDRERDKDRDRERK-RETD 109
+E K+R+ + +++R+ ER ETER R+R+R+R+++R+T R+RD++R RE++ RE D
Sbjct: 144 REIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERD 203
Query: 110 RNRERNRKGGRERDKQTERERDRERERQRQRERERQRQR 148
R+R++ R+ R R+++T R+RD+ER+R+RQRE++R RQ+
Sbjct: 204 RDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQK 242
Score = 119 bits (298), Expect = 2e-27
Identities = 64/137 (46%), Positives = 99/137 (72%), Gaps = 15/137 (10%)
Query: 73 ERETERQRERQRQR--ERKRQTDRERDKDRDRERKRE------TDRNRERNRKGGRERDK 124
ERE +R+RERQR+R ER R+ DRE +KDRDR+RKR+ DR+R+R R G R+R+
Sbjct: 59 ERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRET 118
Query: 125 QTERERDRERERQRQRERERQRQRERK------RETDRERQRWAEREERKKERKKERKKE 178
+TER+ +RER+R R+RE++R+RQR+R+ RE + E+ R ERE + ER ++R++E
Sbjct: 119 ETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERE 178
Query: 179 RKEKKKEEKRREDKKRK 195
R +K++E +R D++R+
Sbjct: 179 R-QKQRETRRDRDRERQ 194
Score = 110 bits (275), Expect = 8e-25
Identities = 60/130 (46%), Positives = 90/130 (69%), Gaps = 11/130 (8%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERE-NRHRQRDRHRE-------RDRQTDRE 53
ERQ ER+R+ DR +E +RER RQRE +RE + RDR RE RDR+ +R+
Sbjct: 121 ERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQ 180
Query: 54 KERERQKERDRQRQRERET-ERETERQRERQRQRERKRQTDRERDK--DRDRERKRETDR 110
K+RE +++RDR+RQRE+E ER+ +RQ+ER++ R R+R+T R+RDK DR+R+R+++ DR
Sbjct: 181 KQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDR 240
Query: 111 NRERNRKGGR 120
+ + GR
Sbjct: 241 QKAIDCVPGR 250
Score = 98.6 bits (244), Expect = 3e-21
Identities = 53/129 (41%), Positives = 82/129 (63%), Gaps = 15/129 (11%)
Query: 80 RERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQ 139
RER+RQRER+RQ R+R K+R RE+ RE +++R+R RK RER + +R+R RER R
Sbjct: 58 RERERQRERERQ--RKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRD 115
Query: 140 RERERQRQRERKRETDRERQRWAERE-------------ERKKERKKERKKERKEKKKEE 186
RE E +RQ ER+R+ DR+R++ ER+ E +K+R +ER+ E+ ++
Sbjct: 116 RETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDR 175
Query: 187 KRREDKKRK 195
+R K+R+
Sbjct: 176 ERERQKQRE 184
Score = 94.7 bits (234), Expect = 5e-20
Identities = 52/101 (51%), Positives = 76/101 (75%), Gaps = 9/101 (8%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
+E +++R RE + G ETER RDR+RER+ Q RE R R RDR R+R+++ DRE++R+RQK
Sbjct: 154 IETEKDRDREREMG-ETERYRDRERERQKQ--RETR-RDRDRERQREKE-DRERDRDRQK 208
Query: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRD 101
ER++ R RERET R+ +++R+R+RQRE+ DR+R K D
Sbjct: 209 EREKDRYRERETGRDRDKERDRERQREK----DRDRQKAID 245
Score = 86.3 bits (212), Expect = 2e-17
Identities = 37/94 (39%), Positives = 67/94 (71%), Gaps = 4/94 (4%)
Query: 104 RKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAE 163
R+RE R RER RK +ER ++ +RE +++R+RQR+R+RERQR R+R DR+R+RW +
Sbjct: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDR----DRKRERWGD 113
Query: 164 REERKKERKKERKKERKEKKKEEKRREDKKRKWG 197
R+ + ++E ++ ++++K+E+ R ++R+ G
Sbjct: 114 RDRETETERQEERERQRDRKREKDRERQRQREIG 147
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 148 bits (374), Expect = 3e-36
Identities = 72/187 (38%), Positives = 135/187 (72%), Gaps = 8/187 (4%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
+R+ ERK+E ++ +RER+++R+RE + + + ++R+R +ER+R K +ER+K+
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERER-----KRKEREKQ 85
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
R +R++ER ++ +++RER+++ R+R+ +ER K+R+RE K+ +R R++ RK R
Sbjct: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKER-KERERENKQRRERKRKKRRKKKRR 144
Query: 122 RDKQTERER-DRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERK 180
++++ E+ER RER+R+++++ ER+++RER R+ ++ + ER ERKKERKKER+K +K
Sbjct: 145 KERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRK-KK 203
Query: 181 EKKKEEK 187
E+KK+ K
Sbjct: 204 ERKKDRK 210
Score = 147 bits (372), Expect = 5e-36
Identities = 71/183 (38%), Positives = 140/183 (76%), Gaps = 9/183 (4%)
Query: 17 TERERDRQRERENQTERENRHRQRDRHRERDR---QTDREKERERQKERDRQRQRERETE 73
T+RE +R++ER ERE R R+R++ R+R+R + + K+RER KER+R+R +ERE +
Sbjct: 30 TQRESERKKERR---EREKRKREREKERKRERGKKEKKKRKKRERGKERERKR-KEREKQ 85
Query: 74 RETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRE 133
R+ R++ER+++++ K++ +R++ R+R++K+E + RER K RER ++ R++ R
Sbjct: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKER-KERERENKQRRERKRKKRRKKKRR 144
Query: 134 RERQRQRER-ERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDK 192
+ER+R++ER +R+R+R+++++ +RE++R R+ERKKER+++ ++ERK+++K+E+R++ +
Sbjct: 145 KERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKE 204
Query: 193 KRK 195
++K
Sbjct: 205 RKK 207
Score = 147 bits (371), Expect = 6e-36
Identities = 78/190 (41%), Positives = 138/190 (72%), Gaps = 9/190 (4%)
Query: 8 KRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQ 67
+RE++R KE R+RERE + +RE +++ + ++R+R KERER K ++R++Q
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERG----KERER-KRKEREKQ 85
Query: 68 RERETERETERQRERQRQRERKRQTDRERDKDRDR-ERKRETDRNRERNRKGGRERDKQT 126
R+ E+E ++++ +++RERK++ RER K ++R ER+RE + RER RK R++ ++
Sbjct: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145
Query: 127 ERERDRER-ERQRQRERERQRQRERKRETDR-ERQRWAEREERKKERKKERKKERKEKKK 184
ER+R++ER +R+R+R++ ++ +RE+KRE +R ER++ ER+ER +ERKKERKKER++KK+
Sbjct: 146 ERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKER-RERKKERKKERRKKKE 204
Query: 185 EEKRREDKKR 194
+K R+ ++
Sbjct: 205 RKKDRKTDRQ 214
Score = 123 bits (308), Expect = 1e-28
Identities = 59/172 (34%), Positives = 122/172 (70%), Gaps = 10/172 (5%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
ER++ERKRE + KE ++ + R+R +E + +R+ R +QR RE++R+ ++++++R+++
Sbjct: 49 EREKERKRERGK-KEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERK 107
Query: 62 RDRQRQR-------ERETERETERQRERQRQRERKRQTDRERDKDRD-RERKRETDRNRE 113
+ +R+R ERE E + R+R+R+++R++KR+ +R+R+K+R RERKR+ + E
Sbjct: 108 QRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEE 167
Query: 114 RNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAERE 165
R +K R R K+ ++ER+R+ R+R++ER+++R+++++R+ DR+ R + +
Sbjct: 168 REKKRERNR-KERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
Score = 81.3 bits (199), Expect = 5e-16
Identities = 41/112 (36%), Positives = 79/112 (70%), Gaps = 6/112 (5%)
Query: 4 QRERKRETDRGKETERERDRQRERENQTERENRHR-QRDRHRER---DRQTDREKERERQ 59
+RERK++ +R KE ERE ++RER+ + R+ + R +R R +ER +R+ + K+ ER+
Sbjct: 111 RRERKKKKER-KERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEERE 169
Query: 60 KERDRQR-QRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDR 110
K+R+R R +R++E ER+ R+R+++R++ER+++ +R++D+ DR+ + R
Sbjct: 170 KKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFR 221
Score = 76.3 bits (186), Expect = 2e-14
Identities = 45/114 (39%), Positives = 79/114 (69%), Gaps = 8/114 (7%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERER-QK 60
ER+RE K+ +R ++ R++ R++ER + E+E +R+R R++ ++ +REK+RER +K
Sbjct: 122 ERERENKQRRERKRKKRRKKKRRKER--KREKE--RGKRERKRKKRKKEEREKKRERNRK 177
Query: 61 ERDRQRQRERETERETERQRERQRQRERK--RQTDRERDKDRDRERKRETDRNR 112
ER ++R+R+ ER+ ER++ER++++ERK R+TDR+ D R RE+ NR
Sbjct: 178 ERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRP-LRESAFNR 230
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 145 bits (366), Expect = 2e-35
Identities = 73/198 (36%), Positives = 141/198 (71%), Gaps = 8/198 (4%)
Query: 5 RERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDR 64
RER+RE + KE ++ER+ +R++E + ERE R R+R++ R+R+R +K +++ER+R
Sbjct: 39 REREREIETRKEGKKERESERKKERR-EREKRKREREKERKRERGKKEKKGERKKEERER 97
Query: 65 Q-RQRERETERETERQRERQRQRERKRQTDRE-RDKDRDRERKRETDRNRERNRKGGRER 122
+ R+RE+E + E+++ ++++++ + +T +E ++++R ERKRE + RER ++ ER
Sbjct: 98 KKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE---ER 154
Query: 123 DKQTERERDRERERQRQRERERQR-QRERKRETDRERQRWAEREERKKERKKERKKERKE 181
+K+ ER+ ++RER++ E+E +R ++ERK RER R ++ER+++ ++ERKKERK+
Sbjct: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKK 214
Query: 182 KKKEEK-RREDKKRKWGE 198
K++ +K R++D++ W E
Sbjct: 215 KEERKKERQKDRQTNWRE 232
Score = 138 bits (348), Expect = 3e-33
Identities = 73/188 (38%), Positives = 123/188 (65%), Gaps = 8/188 (4%)
Query: 2 ERQRERKRETDRGKETERERDRQR-ERENQTERENRHRQR-DRHRERDRQTDREKERER- 58
ER++ER+ R +E E+ER R+R ++E + ER+ R+R R RE++ + EKE+ +
Sbjct: 58 ERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKK 117
Query: 59 --QKERDRQRQRERETERETERQRERQRQRERK---RQTDRERDKDRDRERKRETDRNRE 113
+KER R + +E ER+ ER+RE +++RERK R+ +RER + + RERK+ ++ E
Sbjct: 118 KEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEE 177
Query: 114 RNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKK 173
R K +ER K+ ++R++ER+R+ RER+++R++K E +ERQ+ + R+KER K
Sbjct: 178 RKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGK 237
Query: 174 ERKKERKE 181
+KERK+
Sbjct: 238 RERKERKK 245
Score = 138 bits (347), Expect = 4e-33
Identities = 62/195 (31%), Positives = 137/195 (70%), Gaps = 5/195 (2%)
Query: 2 ERQRERKRETDRGKETERERDRQRERE-NQTERENRHRQRDRHRERDRQTDREKERERQK 60
ER+ ERK+E ++ +RER+++R+RE + E++ ++ +R R++ R+ KE E ++
Sbjct: 54 ERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKE 113
Query: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDK-DRDRERKRETDRNRERNRKGG 119
+R ++ ++ER + ++RER+ +R+R+ + +RER K +R++ER+R+ + RER + G
Sbjct: 114 KRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGE 173
Query: 120 RERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKER 179
+E +++ + ++R++ + ++ER+++R+R+ +RE +ER++ +EERKKER+K+R+
Sbjct: 174 KEEERKEKERKERKKRERNRKERKKERERKERRERKKERKK---KEERKKERQKDRQTNW 230
Query: 180 KEKKKEEKRREDKKR 194
+EK++ ++ R+++K+
Sbjct: 231 REKERGKRERKERKK 245
Score = 134 bits (337), Expect = 5e-32
Identities = 73/207 (35%), Positives = 138/207 (66%), Gaps = 17/207 (8%)
Query: 2 ERQRERKRETDRGKETERERDRQ----RERENQTERENRHRQRDRHRERDRQTDREKERE 57
ER+ E ++E + +E+ER+++R+ R+RE + ER+ ++++ ER ++ K+R
Sbjct: 42 EREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRR 101
Query: 58 RQKERDRQRQRERETERE-TERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNR 116
R+KE ++E+ ++E ER R + +ER+R+ +R+R++ ++RERK+E +R +ER R
Sbjct: 102 REKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE-EREKERER 160
Query: 117 KGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKK--E 174
K ++R+++ E++ ER+ + ++ER+++ + ++R+ +RER+ ER ERKKERKK E
Sbjct: 161 KERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERK---ERRERKKERKKKEE 217
Query: 175 RKKERKE------KKKEEKRREDKKRK 195
RKKER++ ++KE +RE K+RK
Sbjct: 218 RKKERQKDRQTNWREKERGKRERKERK 244
Score = 44.3 bits (103), Expect = 7e-05
Identities = 25/45 (55%), Positives = 33/45 (73%), Gaps = 2/45 (4%)
Query: 156 RERQRWAE-REERKKERKKERKKERKEKKKEEKRREDKKRKWGEG 199
RER+R E R+E KKER+ ERKKER+E++K KR +K+RK G
Sbjct: 39 REREREIETRKEGKKERESERKKERREREKR-KREREKERKRERG 82
Score = 29.3 bits (64), Expect = 2.4
Identities = 17/36 (47%), Positives = 26/36 (72%), Gaps = 3/36 (8%)
Query: 163 EREERKKERKKERKKE-RKEKKKEEK--RREDKKRK 195
+ E R++ER+ E +KE +KE++ E K RRE +KRK
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRK 70
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 140 bits (353), Expect = 7e-34
Identities = 71/206 (34%), Positives = 127/206 (61%), Gaps = 21/206 (10%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
R R R+++ R K ++R + RER R++R R R + +D + ++ KE+ER KE+
Sbjct: 340 RSRSRQKDRRRSKSPHKKRSKSRER-----RKSRSRSHSRDKRKDTR-EKIKEKERVKEK 393
Query: 63 DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRER 122
DR+++RERE ERE E++R + + R+++R+ DRE+DK++DRER+RE + ++R+++ +E+
Sbjct: 394 DREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQ 453
Query: 123 DKQTERERDRERERQRQRERER------------QRQRERKRETDRERQRWAEREERKK- 169
DK+ ERE+DR +E +R++++ +R R RE R R R + R R
Sbjct: 454 DKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSK 513
Query: 170 --ERKKERKKERKEKKKEEKRREDKK 193
+RK R + + K++K+RE ++
Sbjct: 514 TIKRKSSRSPSPRSRNKKDKKREKER 539
Score = 137 bits (344), Expect = 8e-33
Identities = 63/197 (31%), Positives = 121/197 (61%), Gaps = 8/197 (4%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
++R + RE + + RD++++ + + + R +++DR +ER+R+ +REKE+ER K +
Sbjct: 356 KKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNK 415
Query: 63 DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRER 122
DR ++RE++ E++ E+ RER+R++E ++ D+E++K++D+E++RE DR++E + K R++
Sbjct: 416 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK--RKK 473
Query: 123 DKQTE------RERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERK 176
DK++ R R R+R R R R R T + +R + R + R K+ K
Sbjct: 474 DKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDK 533
Query: 177 KERKEKKKEEKRREDKK 193
K KE+ +RRE ++
Sbjct: 534 KREKERDHISERRERER 550
Score = 133 bits (335), Expect = 9e-32
Identities = 61/195 (31%), Positives = 123/195 (63%), Gaps = 12/195 (6%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
ER+ R R R K + R + +Q++ +R R R R++DR+ + ++R K
Sbjct: 302 ERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKS 361
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
R+R++ R R R+ +R+ RE+ ++ +R ++KDR++ER+RE +R +E+ R ++
Sbjct: 362 RERRKSRSRSHSRD-----KRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKD 416
Query: 122 RDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKE 181
RDK ER+++RE+ ++++RER+R++E +++ D+E+++ ++++KER+K+R KE E
Sbjct: 417 RDK----EREKDREKDKEKDREREREKEHEKDRDKEKEK---EQDKEKEREKDRSKEIDE 469
Query: 182 KKKEEKRREDKKRKW 196
K+K++K+ R +
Sbjct: 470 KRKKDKKSRTPPRSY 484
Score = 133 bits (334), Expect = 1e-31
Identities = 64/212 (30%), Positives = 128/212 (60%), Gaps = 20/212 (9%)
Query: 4 QRERKRETDRGKETERERDRQRERE-NQTERENRHRQRDRHRERDRQTDREKERE-RQKE 61
+R+R + R + R R RQ++R +++ + R + R+R + R R R+K ++ R+K
Sbjct: 325 RRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKI 384
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
++++R +E++ E+E ER++ER++++ER + DR++++++DRE+ +E DR RER ++ ++
Sbjct: 385 KEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKD 444
Query: 122 RDKQTERERDRERERQRQRERERQRQRE----------------RKRETDRERQRWAERE 165
RDK+ E+E+D+E+ER++ R +E +R+ R R + RER+R R
Sbjct: 445 RDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRS 504
Query: 166 ERKKER--KKERKKERKEKKKEEKRREDKKRK 195
+ R K ++K + + ++DKKR+
Sbjct: 505 SSRSPRTSKTIKRKSSRSPSPRSRNKKDKKRE 536
Score = 128 bits (321), Expect = 4e-30
Identities = 68/206 (33%), Positives = 123/206 (59%), Gaps = 17/206 (8%)
Query: 1 MERQRERKR------ETDRGKETERE--RDRQRERENQTERENRHRQRDRHRERDRQTDR 52
M+R RE + E + GK ER+ R R R H +R R + + R
Sbjct: 279 MKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSH 338
Query: 53 EKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNR 112
+ R RQK+R R + ++ + ER++ R R R ++ D R+K +++ER +E DR +
Sbjct: 339 NRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDT-REKIKEKERVKEKDREK 397
Query: 113 ERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERK 172
ER R+ RE++K+ + +DR++ER++ RE+++++ RER+RE + E+ R +++KE++
Sbjct: 398 EREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDR-----DKEKEKE 452
Query: 173 KERKKER-KEKKKE--EKRREDKKRK 195
++++KER K++ KE EKR++DKK +
Sbjct: 453 QDKEKEREKDRSKEIDEKRKKDKKSR 478
Score = 122 bits (307), Expect = 2e-28
Identities = 65/203 (32%), Positives = 123/203 (60%), Gaps = 25/203 (12%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
+++ER +E DR KE ERE++R++E+E + + ++R ++R++ RE+D++ DRE+ERE++ E+
Sbjct: 385 KEKERVKEKDREKEREREKEREKEKE-RGKNKDRDKEREKDREKDKEKDREREREKEHEK 443
Query: 63 DRQRQRERETERETERQRERQRQRERKRQTDRE------------RDKDRDRERKRETDR 110
DR +++E+E ++E ER+++R ++ + KR+ D++ R + RER+R R
Sbjct: 444 DRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSR 503
Query: 111 NRERN--------RKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWA 162
+ R+ RK R ++ ++D++RE++R ER RER+R T R+
Sbjct: 504 SSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISER---RERERSTSM-RKSSN 559
Query: 163 EREERKKERKKERKKERKEKKKE 185
+R+ ++K K + KE KE
Sbjct: 560 DRDGKEKLEKNSTSLKEKEHNKE 582
Score = 120 bits (302), Expect = 6e-28
Identities = 60/198 (30%), Positives = 118/198 (59%), Gaps = 8/198 (4%)
Query: 5 RERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDR 64
RE+ +E +R KE +RE++R+RE+E + E+E R + +DR +ER++ +++KE++R++ER++
Sbjct: 381 REKIKEKERVKEKDREKEREREKEREKEKE-RGKNKDRDKEREKDREKDKEKDREREREK 439
Query: 65 QRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDK 124
+ +++R+ E+E E+ +E++R+++R ++ D +R KD+ + R+R RER +
Sbjct: 440 EHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRR 499
Query: 125 QTERERDRERERQRQRERERQR----QRERKRETDRERQRWAEREERKKERKKERKK--- 177
+ R R + +R+ R + K++ RE++R E R++ER +K
Sbjct: 500 RRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSN 559
Query: 178 ERKEKKKEEKRREDKKRK 195
+R K+K EK K K
Sbjct: 560 DRDGKEKLEKNSTSLKEK 577
Score = 115 bits (288), Expect = 3e-26
Identities = 51/191 (26%), Positives = 116/191 (60%), Gaps = 2/191 (1%)
Query: 8 KRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQ 67
KR+ R K E+ER ++++RE + ERE + R++++ R +++ D+E+E++R+K++++ R+
Sbjct: 376 KRKDTREKIKEKERVKEKDREKERERE-KEREKEKERGKNKDRDKEREKDREKDKEKDRE 434
Query: 68 RERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTE 127
RERE E E +R +E++++++++++ +++R K+ D +RK++ R + +
Sbjct: 435 REREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSS 494
Query: 128 RERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEK 187
RER R R R R + +RK + R ++++K+E++++ ER+E+++
Sbjct: 495 RERRRRRSRSSSRSPRTSKTIKRK-SSRSPSPRSRNKKDKKREKERDHISERRERERSTS 553
Query: 188 RREDKKRKWGE 198
R+ + G+
Sbjct: 554 MRKSSNDRDGK 564
Score = 100 bits (250), Expect = 6e-22
Identities = 58/193 (30%), Positives = 110/193 (56%), Gaps = 16/193 (8%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
+ R+++RE DR K+ E++R+R+RE+E++ +R+ + +++++ +E++R+ DR KE + ++++
Sbjct: 415 KDRDKEREKDREKDKEKDREREREKEHEKDRD-KEKEKEQDKEKEREKDRSKEIDEKRKK 473
Query: 63 DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRN---RERNRKGG 119
D++ + + + R R R+R R+R R + KR++ R+ R RN+K
Sbjct: 474 DKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKK-- 531
Query: 120 RERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKER 179
DK+ E+ERD ER RERER RK DR+ + E+ E+ KE++ +
Sbjct: 532 ---DKKREKERDHISER---RERERSTSM-RKSSNDRDGK---EKLEKNSTSLKEKEHNK 581
Query: 180 KEKKKEEKRREDK 192
+ K +DK
Sbjct: 582 EPDSSVSKEVDDK 594
Score = 76.6 bits (187), Expect = 1e-14
Identities = 44/146 (30%), Positives = 76/146 (52%), Gaps = 4/146 (2%)
Query: 52 REKERERQKERDRQRQRERETERETERQRERQ--RQRERKRQTDRERDKDRDRERKRETD 109
+E E ++ R+ Q E E+ + ER+ R R R R K R RKR
Sbjct: 273 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSR-RKRSQS 331
Query: 110 RNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKK 169
++R R+ R R K R + ++R + RER + R R R+ ++ + + +ER K
Sbjct: 332 KHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVK 391
Query: 170 ERKKERKKER-KEKKKEEKRREDKKR 194
E+ +E+++ER KE++KE++R ++K R
Sbjct: 392 EKDREKEREREKEREKEKERGKNKDR 417
Score = 74.7 bits (182), Expect = 5e-14
Identities = 46/150 (30%), Positives = 82/150 (54%), Gaps = 10/150 (6%)
Query: 54 KERERQKERDRQRQR------ERETERETERQRERQRQRERKRQTDRERDKDRDRERKRE 107
KE E +R R+ Q E E+ + ER+ R R R + + R R+R +
Sbjct: 273 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSR-RKRSQS 331
Query: 108 TDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRER-KRETDRERQRWAER-E 165
R+R NR R++D++ + ++R + R+R + R R R KR+ RE+ + ER +
Sbjct: 332 KHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVK 391
Query: 166 ERKKERKKERKKERKEKKKEEKRREDKKRK 195
E+ +E+++ER+KER EK+KE + +D+ ++
Sbjct: 392 EKDREKEREREKER-EKEKERGKNKDRDKE 420
Score = 65.5 bits (158), Expect = 3e-11
Identities = 49/207 (23%), Positives = 91/207 (43%), Gaps = 70/207 (33%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERE---- 57
E+++ER + DR KE E++R++ +E++ + ERE H ++DR +E++++ D+EKERE
Sbjct: 406 EKEKERGKNKDRDKEREKDREKDKEKDREREREKEH-EKDRDKEKEKEQDKEKEREKDRS 464
Query: 58 --------------------------RQKERDRQRQRERET------------------- 72
R R+R+R+R R +
Sbjct: 465 KEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPS 524
Query: 73 ---------ERETER-----QRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKG 118
+RE ER +RER+R ++ ++ DRD + K E + + ++
Sbjct: 525 PRSRNKKDKKREKERDHISERRERERSTSMRKSSN-----DRDGKEKLEKNSTSLKEKEH 579
Query: 119 GRERDKQTERERDRERERQRQRERERQ 145
+E D +E D +++ R E + Q
Sbjct: 580 NKEPDSSVSKEVD-DKDAPRTEENKIQ 605
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 140 bits (353), Expect = 7e-34
Identities = 71/206 (34%), Positives = 127/206 (61%), Gaps = 21/206 (10%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
R R R+++ R K ++R + RER R++R R R + +D + ++ KE+ER KE+
Sbjct: 224 RSRSRQKDRRRSKSPHKKRSKSRER-----RKSRSRSHSRDKRKDTR-EKIKEKERVKEK 277
Query: 63 DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRER 122
DR+++RERE ERE E++R + + R+++R+ DRE+DK++DRER+RE + ++R+++ +E+
Sbjct: 278 DREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQ 337
Query: 123 DKQTERERDRERERQRQRERER------------QRQRERKRETDRERQRWAEREERKK- 169
DK+ ERE+DR +E +R++++ +R R RE R R R + R R
Sbjct: 338 DKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSK 397
Query: 170 --ERKKERKKERKEKKKEEKRREDKK 193
+RK R + + K++K+RE ++
Sbjct: 398 TIKRKSSRSPSPRSRNKKDKKREKER 423
Score = 137 bits (344), Expect = 8e-33
Identities = 63/197 (31%), Positives = 121/197 (61%), Gaps = 8/197 (4%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
++R + RE + + RD++++ + + + R +++DR +ER+R+ +REKE+ER K +
Sbjct: 240 KKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNK 299
Query: 63 DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRER 122
DR ++RE++ E++ E+ RER+R++E ++ D+E++K++D+E++RE DR++E + K R++
Sbjct: 300 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK--RKK 357
Query: 123 DKQTE------RERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERK 176
DK++ R R R+R R R R R T + +R + R + R K+ K
Sbjct: 358 DKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDK 417
Query: 177 KERKEKKKEEKRREDKK 193
K KE+ +RRE ++
Sbjct: 418 KREKERDHISERRERER 434
Score = 133 bits (335), Expect = 9e-32
Identities = 61/195 (31%), Positives = 123/195 (63%), Gaps = 12/195 (6%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
ER+ R R R K + R + +Q++ +R R R R++DR+ + ++R K
Sbjct: 186 ERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKS 245
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
R+R++ R R R+ +R+ RE+ ++ +R ++KDR++ER+RE +R +E+ R ++
Sbjct: 246 RERRKSRSRSHSRD-----KRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKD 300
Query: 122 RDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKE 181
RDK ER+++RE+ ++++RER+R++E +++ D+E+++ ++++KER+K+R KE E
Sbjct: 301 RDK----EREKDREKDKEKDREREREKEHEKDRDKEKEK---EQDKEKEREKDRSKEIDE 353
Query: 182 KKKEEKRREDKKRKW 196
K+K++K+ R +
Sbjct: 354 KRKKDKKSRTPPRSY 368
Score = 133 bits (334), Expect = 1e-31
Identities = 64/212 (30%), Positives = 128/212 (60%), Gaps = 20/212 (9%)
Query: 4 QRERKRETDRGKETERERDRQRERE-NQTERENRHRQRDRHRERDRQTDREKERE-RQKE 61
+R+R + R + R R RQ++R +++ + R + R+R + R R R+K ++ R+K
Sbjct: 209 RRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKI 268
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
++++R +E++ E+E ER++ER++++ER + DR++++++DRE+ +E DR RER ++ ++
Sbjct: 269 KEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKD 328
Query: 122 RDKQTERERDRERERQRQRERERQRQRE----------------RKRETDRERQRWAERE 165
RDK+ E+E+D+E+ER++ R +E +R+ R R + RER+R R
Sbjct: 329 RDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRS 388
Query: 166 ERKKER--KKERKKERKEKKKEEKRREDKKRK 195
+ R K ++K + + ++DKKR+
Sbjct: 389 SSRSPRTSKTIKRKSSRSPSPRSRNKKDKKRE 420
Score = 128 bits (321), Expect = 4e-30
Identities = 68/206 (33%), Positives = 123/206 (59%), Gaps = 17/206 (8%)
Query: 1 MERQRERKR------ETDRGKETERE--RDRQRERENQTERENRHRQRDRHRERDRQTDR 52
M+R RE + E + GK ER+ R R R H +R R + + R
Sbjct: 163 MKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSH 222
Query: 53 EKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNR 112
+ R RQK+R R + ++ + ER++ R R R ++ D R+K +++ER +E DR +
Sbjct: 223 NRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDT-REKIKEKERVKEKDREK 281
Query: 113 ERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERK 172
ER R+ RE++K+ + +DR++ER++ RE+++++ RER+RE + E+ R +++KE++
Sbjct: 282 EREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDR-----DKEKEKE 336
Query: 173 KERKKER-KEKKKE--EKRREDKKRK 195
++++KER K++ KE EKR++DKK +
Sbjct: 337 QDKEKEREKDRSKEIDEKRKKDKKSR 362
Score = 122 bits (307), Expect = 2e-28
Identities = 65/203 (32%), Positives = 123/203 (60%), Gaps = 25/203 (12%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
+++ER +E DR KE ERE++R++E+E + + ++R ++R++ RE+D++ DRE+ERE++ E+
Sbjct: 269 KEKERVKEKDREKEREREKEREKEKE-RGKNKDRDKEREKDREKDKEKDREREREKEHEK 327
Query: 63 DRQRQRERETERETERQRERQRQRERKRQTDRE------------RDKDRDRERKRETDR 110
DR +++E+E ++E ER+++R ++ + KR+ D++ R + RER+R R
Sbjct: 328 DRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSR 387
Query: 111 NRERN--------RKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWA 162
+ R+ RK R ++ ++D++RE++R ER RER+R T R+
Sbjct: 388 SSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISER---RERERSTSM-RKSSN 443
Query: 163 EREERKKERKKERKKERKEKKKE 185
+R+ ++K K + KE KE
Sbjct: 444 DRDGKEKLEKNSTSLKEKEHNKE 466
Score = 120 bits (302), Expect = 6e-28
Identities = 60/198 (30%), Positives = 118/198 (59%), Gaps = 8/198 (4%)
Query: 5 RERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDR 64
RE+ +E +R KE +RE++R+RE+E + E+E R + +DR +ER++ +++KE++R++ER++
Sbjct: 265 REKIKEKERVKEKDREKEREREKEREKEKE-RGKNKDRDKEREKDREKDKEKDREREREK 323
Query: 65 QRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDK 124
+ +++R+ E+E E+ +E++R+++R ++ D +R KD+ + R+R RER +
Sbjct: 324 EHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRR 383
Query: 125 QTERERDRERERQRQRERERQR----QRERKRETDRERQRWAEREERKKERKKERKK--- 177
+ R R + +R+ R + K++ RE++R E R++ER +K
Sbjct: 384 RRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSN 443
Query: 178 ERKEKKKEEKRREDKKRK 195
+R K+K EK K K
Sbjct: 444 DRDGKEKLEKNSTSLKEK 461
Score = 115 bits (288), Expect = 3e-26
Identities = 51/191 (26%), Positives = 116/191 (60%), Gaps = 2/191 (1%)
Query: 8 KRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQ 67
KR+ R K E+ER ++++RE + ERE + R++++ R +++ D+E+E++R+K++++ R+
Sbjct: 260 KRKDTREKIKEKERVKEKDREKERERE-KEREKEKERGKNKDRDKEREKDREKDKEKDRE 318
Query: 68 RERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTE 127
RERE E E +R +E++++++++++ +++R K+ D +RK++ R + +
Sbjct: 319 REREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSS 378
Query: 128 RERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEK 187
RER R R R R + +RK + R ++++K+E++++ ER+E+++
Sbjct: 379 RERRRRRSRSSSRSPRTSKTIKRK-SSRSPSPRSRNKKDKKREKERDHISERRERERSTS 437
Query: 188 RREDKKRKWGE 198
R+ + G+
Sbjct: 438 MRKSSNDRDGK 448
Score = 100 bits (250), Expect = 6e-22
Identities = 58/193 (30%), Positives = 110/193 (56%), Gaps = 16/193 (8%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
+ R+++RE DR K+ E++R+R+RE+E++ +R+ + +++++ +E++R+ DR KE + ++++
Sbjct: 299 KDRDKEREKDREKDKEKDREREREKEHEKDRD-KEKEKEQDKEKEREKDRSKEIDEKRKK 357
Query: 63 DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRN---RERNRKGG 119
D++ + + + R R R+R R+R R + KR++ R+ R RN+K
Sbjct: 358 DKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKK-- 415
Query: 120 RERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKER 179
DK+ E+ERD ER RERER RK DR+ + E+ E+ KE++ +
Sbjct: 416 ---DKKREKERDHISER---RERERSTSM-RKSSNDRDGK---EKLEKNSTSLKEKEHNK 465
Query: 180 KEKKKEEKRREDK 192
+ K +DK
Sbjct: 466 EPDSSVSKEVDDK 478
Score = 76.6 bits (187), Expect = 1e-14
Identities = 44/146 (30%), Positives = 76/146 (52%), Gaps = 4/146 (2%)
Query: 52 REKERERQKERDRQRQRERETERETERQRERQ--RQRERKRQTDRERDKDRDRERKRETD 109
+E E ++ R+ Q E E+ + ER+ R R R R K R RKR
Sbjct: 157 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSR-RKRSQS 215
Query: 110 RNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKK 169
++R R+ R R K R + ++R + RER + R R R+ ++ + + +ER K
Sbjct: 216 KHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVK 275
Query: 170 ERKKERKKER-KEKKKEEKRREDKKR 194
E+ +E+++ER KE++KE++R ++K R
Sbjct: 276 EKDREKEREREKEREKEKERGKNKDR 301
Score = 74.7 bits (182), Expect = 5e-14
Identities = 46/150 (30%), Positives = 82/150 (54%), Gaps = 10/150 (6%)
Query: 54 KERERQKERDRQRQR------ERETERETERQRERQRQRERKRQTDRERDKDRDRERKRE 107
KE E +R R+ Q E E+ + ER+ R R R + + R R+R +
Sbjct: 157 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSR-RKRSQS 215
Query: 108 TDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRER-KRETDRERQRWAER-E 165
R+R NR R++D++ + ++R + R+R + R R R KR+ RE+ + ER +
Sbjct: 216 KHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVK 275
Query: 166 ERKKERKKERKKERKEKKKEEKRREDKKRK 195
E+ +E+++ER+KER EK+KE + +D+ ++
Sbjct: 276 EKDREKEREREKER-EKEKERGKNKDRDKE 304
Score = 65.5 bits (158), Expect = 3e-11
Identities = 49/207 (23%), Positives = 91/207 (43%), Gaps = 70/207 (33%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERE---- 57
E+++ER + DR KE E++R++ +E++ + ERE H ++DR +E++++ D+EKERE
Sbjct: 290 EKEKERGKNKDRDKEREKDREKDKEKDREREREKEH-EKDRDKEKEKEQDKEKEREKDRS 348
Query: 58 --------------------------RQKERDRQRQRERET------------------- 72
R R+R+R+R R +
Sbjct: 349 KEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPS 408
Query: 73 ---------ERETER-----QRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKG 118
+RE ER +RER+R ++ ++ DRD + K E + + ++
Sbjct: 409 PRSRNKKDKKREKERDHISERRERERSTSMRKSSN-----DRDGKEKLEKNSTSLKEKEH 463
Query: 119 GRERDKQTERERDRERERQRQRERERQ 145
+E D +E D +++ R E + Q
Sbjct: 464 NKEPDSSVSKEVD-DKDAPRTEENKIQ 489
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 129 bits (323), Expect = 2e-30
Identities = 69/204 (33%), Positives = 113/204 (55%), Gaps = 13/204 (6%)
Query: 3 RQRERKRETDRGKE-----TERERDRQRERENQTERE-NRHRQRDRHRER------DRQT 50
R R+ K++ G E ER R R R R R R R HRE DR+
Sbjct: 236 RPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDREL 295
Query: 51 DREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDR 110
+REKER+R + ++R++ER R +R ER+R R R+R R R +DR +R R+ DR
Sbjct: 296 EREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDR-RDRDR 354
Query: 111 NRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKE 170
RE+ + GR RD+ ++ER ERE++R+R RER +++ + E + ++ + + + R ++
Sbjct: 355 EREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRD 414
Query: 171 RKKERKKERKEKKKEEKRREDKKR 194
K++ KKE+K + + R+ + R
Sbjct: 415 DKRDSKKEKKHSRSRSRERKHRSR 438
Score = 125 bits (314), Expect = 2e-29
Identities = 70/203 (34%), Positives = 112/203 (55%), Gaps = 12/203 (5%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRER--DRQTDREKERERQK 60
R R RE +RE +R++ER+ + ERE + R+++R R R DR +R + R R++
Sbjct: 277 RSRSHHREGHGSSSFDRELEREKERQ-RLEREAKEREKERRRSRSIDRGLERRRSRSRER 335
Query: 61 ERDRQRQRERE---TERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRK 117
R R R R+R+ +R+ ER++E +R R R R D+ER +R++ER+R +R++E+ +
Sbjct: 336 HRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSR 395
Query: 118 GGRE-----RDKQTERERDRERERQRQRERERQRQRERK-RETDRERQRWAEREERKKER 171
G E DK R RD +R+ +++++ R R RERK R R R R KE+
Sbjct: 396 GEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEK 455
Query: 172 KKERKKERKEKKKEEKRREDKKR 194
+ K E KEK + R + R
Sbjct: 456 SSKHKNESKEKSNKRSRSGSQGR 478
Score = 118 bits (296), Expect = 3e-27
Identities = 66/201 (32%), Positives = 109/201 (54%), Gaps = 11/201 (5%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
E++R R R DRG E R R R+R R R+ + +RDR RER+++ +R + R+R +
Sbjct: 312 EKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYD 371
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKD--RDRERKRETDRNRERNRKGG 119
++R +RE+E ER ER +E QR R + + DKD R R+ KR++ + ++ +R
Sbjct: 372 KERGNEREKERERSRERSKE-QRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRS 430
Query: 120 RERDKQTERERDR---ERERQRQRERERQRQRERKRETDRE----RQRWAEREERKKERK 172
RER K R R R +R R R +E+ + + E K ++++ Q + E+ K+R+
Sbjct: 431 RER-KHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKRE 489
Query: 173 KERKKERKEKKKEEKRREDKK 193
KE+ K+ K R K+
Sbjct: 490 HSPSKEKSRKRSRSKERSHKR 510
Score = 114 bits (286), Expect = 4e-26
Identities = 65/200 (32%), Positives = 113/200 (56%), Gaps = 14/200 (7%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
ER R R R DR K R+RDR+RE+EN+ R R+RDR +++R +REKERER +E
Sbjct: 334 ERHRSRSRSRDR-KGDRRDRDREREKENE-----RGRRRDRDYDKERGNEREKERERSRE 387
Query: 62 RDR-QRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
R + QR R E++ + ++ +R R+ KR + +E+ R R R+R+ R+R R+R G+
Sbjct: 388 RSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERK-HRSRSRSRNAGK 446
Query: 121 ERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAERE-ERKKERKKERKKER 179
+++ + + + +++ +R R + R E+ + E ++K RK+ R KER
Sbjct: 447 RSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKER 506
Query: 180 KEKK-----KEEKRREDKKR 194
K+ K++ + D++R
Sbjct: 507 SHKRDHSDSKDQSDKHDRRR 526
Score = 109 bits (273), Expect = 1e-24
Identities = 63/184 (34%), Positives = 100/184 (54%), Gaps = 13/184 (7%)
Query: 23 RQRERENQTERENRHRQRDRH--RERDRQTDREKERERQKERDRQRQRERETERETERQR 80
+ R R+ + + + + DRH R R R R R R R R RE + R
Sbjct: 234 KTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDR 293
Query: 81 ERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQ-RQ 139
E +R++ER+R ++++++R R R DR ER R RER + R RDR+ +R+ R
Sbjct: 294 ELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRD 353
Query: 140 RERERQRQRERKRETDRERQRWAERE---ERKKERKKERK-------KERKEKKKEEKRR 189
RERE++ +R R+R+ D +++R ERE ER +ER KE++ K+ KE K + + R
Sbjct: 354 REREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHR 413
Query: 190 EDKK 193
+DK+
Sbjct: 414 DDKR 417
Score = 103 bits (257), Expect = 1e-22
Identities = 58/204 (28%), Positives = 115/204 (56%), Gaps = 20/204 (9%)
Query: 3 RQRERK---RETDRGKETERERDRQRERENQTEREN-RHRQRDRHRERDR-QTDREKERE 57
R R+RK R+ DR +E E ER R+R+R+ ER N R ++R+R RER + Q R + E
Sbjct: 341 RSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEE 400
Query: 58 RQKERDRQRQRERETERETERQRERQRQRERKR------------QTDRERDKDRDRERK 105
++ + D+ +R R+ +R+++++++ R R R+R + R R K++ + K
Sbjct: 401 KKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHK 460
Query: 106 RET-DRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRER--KRETDRERQRWA 162
E+ +++ +R+R G + R E+ + RE +++ R+R R +ER KR+ + +
Sbjct: 461 NESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSD 520
Query: 163 EREERKKERKKERKKERKEKKKEE 186
+ + R+ + ++ +E++ K K+E
Sbjct: 521 KHDRRRSQSIEQESQEKQHKNKDE 544
Score = 94.4 bits (233), Expect = 6e-20
Identities = 62/180 (34%), Positives = 96/180 (53%), Gaps = 15/180 (8%)
Query: 30 QTERENRHRQRDRHRERDRQTDREK-ERERQKERDRQRQRERETERETERQRERQRQRER 88
Q + + + R R ++D + E+ +R ++ R R +R R R R R RE
Sbjct: 226 QKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREG 285
Query: 89 KRQT--DRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQR 146
+ DRE +++++R+R + RE+ R+ R D+ ER R R RER R R R R R
Sbjct: 286 HGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDR 345
Query: 147 QRERKRETDRERQRWAEREERK-----KERKKERKKER---KEKKKEEKRR---EDKKRK 195
+ +R R+ DRER++ ER R+ KER ER+KER +E+ KE++ R E+KK K
Sbjct: 346 KGDR-RDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHK 404
Score = 51.2 bits (121), Expect = 6e-07
Identities = 35/122 (28%), Positives = 56/122 (45%), Gaps = 5/122 (4%)
Query: 83 QRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRER 142
Q+ +++ +T + K +E E DR+ ER R R R R R R RE
Sbjct: 226 QKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREG 285
Query: 143 ERQRQRERKRETDRERQRWA----ERE-ERKKERKKERKKERKEKKKEEKRREDKKRKWG 197
+R+ E ++ERQR ERE ER++ R +R ER+ + E+ R + +
Sbjct: 286 HGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDR 345
Query: 198 EG 199
+G
Sbjct: 346 KG 347
Score = 35.8 bits (81), Expect = 0.025
Identities = 19/81 (23%), Positives = 38/81 (46%), Gaps = 6/81 (7%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTEREN-RHRQRDRHRERDR-----QTDREKE 55
E+ +R R +G+ E+ ++RE E+ R R ++R +RD Q+D+
Sbjct: 465 EKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDR 524
Query: 56 RERQKERDRQRQRERETERET 76
R Q ++++ + + ET
Sbjct: 525 RRSQSIEQESQEKQHKNKDET 545
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 126 bits (317), Expect = 1e-29
Identities = 65/189 (34%), Positives = 120/189 (63%), Gaps = 5/189 (2%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
E+Q RK+E +R ++ E R++Q RE Q ER + +R++ R++Q RE+E ER
Sbjct: 303 EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEER--- 359
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
R++Q +RE+E ER E+Q R++Q R++Q RE+ R+++ +RE RE+ + ++
Sbjct: 360 REQQLRREQEEERR-EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 418
Query: 122 RDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKE 181
++ + R++E ER Q+ + +R++ KRE + ER+ W +REE + ++ER+K++ +
Sbjct: 419 LRREQQLRREQEEERHEQKHEQERREQRLKREQE-ERRDWLKREEETERHEQERRKQQLK 477
Query: 182 KKKEEKRRE 190
+ +EE+RRE
Sbjct: 478 RDQEEERRE 486
Score = 122 bits (305), Expect = 3e-28
Identities = 63/207 (30%), Positives = 126/207 (60%), Gaps = 13/207 (6%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
E+Q ER+ + +R ++ E R++Q RE + RE + R+ R++Q RE+E ER+++
Sbjct: 316 EQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQ 375
Query: 62 ---RDRQRQRERETERETERQRERQRQRE----RKRQTDRERDKDRDRERKRETDRNRER 114
R++Q +RE++ RE + +RE+Q +RE R++Q RE+ R+++ +RE + R
Sbjct: 376 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHE 435
Query: 115 NRKGGRERDKQTERERDRERE-RQRQRERERQRQRERKRETDRE-----RQRWAEREERK 168
+ R+++ +RE++ R+ +R+ E ER Q RK++ R+ R+RW + EE +
Sbjct: 436 QKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEE 495
Query: 169 KERKKERKKERKEKKKEEKRREDKKRK 195
+ ++ER++++ +++EE+R + KR+
Sbjct: 496 RREQQERREQQLRREQEERREQRLKRQ 522
Score = 120 bits (300), Expect = 1e-27
Identities = 66/207 (31%), Positives = 132/207 (63%), Gaps = 13/207 (6%)
Query: 2 ERQRERKRETDRGKETERE--RDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQ 59
+RQRE + E ++ ++ ER+ R ++E E Q +R R +Q R +E +R+ +E+ RE+Q
Sbjct: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQ 325
Query: 60 KERDRQRQR-ERETERETERQRERQRQRE-----RKRQTDRERDKDRDRE---RKRETDR 110
+ R++Q +R E++ RE E +RE+Q +RE R++Q RE++++R + R+++ R
Sbjct: 326 ERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRR 385
Query: 111 NRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKE 170
++ R+ R++Q RE+ RE+Q +RE++ +R+++ +RE + ER +ER+++
Sbjct: 386 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQ 445
Query: 171 RKKERKKERKE--KKKEEKRREDKKRK 195
R K ++ER++ K++EE R +++R+
Sbjct: 446 RLKREQEERRDWLKREEETERHEQERR 472
Score = 118 bits (295), Expect = 4e-27
Identities = 71/226 (31%), Positives = 133/226 (58%), Gaps = 31/226 (13%)
Query: 1 MERQRERKRETDRGKETERER-DRQRERENQTERENRHRQRDRHRERDRQTDREKE--RE 57
+ R++E +RE +E E ER ++Q RE + ER + +R++ R++Q RE++ RE
Sbjct: 339 LRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRRE 398
Query: 58 RQKERDRQRQRERETERETERQRERQRQRE--------------RKRQTDRERDKDRD-R 102
+Q R++Q +RE++ RE + +RE+Q +RE R+++ RE+++ RD
Sbjct: 399 QQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWL 458
Query: 103 ERKRETDRNRERNRKGGRERDKQTE-------------RERDRERERQRQRERERQRQRE 149
+R+ ET+R+ + RK +RD++ E RE+ RE+Q +RE+E +R++
Sbjct: 459 KREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQR 518
Query: 150 RKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRK 195
KR+ + ER + R E++ R++E ++E+ K++EEKR E ++R+
Sbjct: 519 LKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERRE 564
Score = 115 bits (287), Expect = 3e-26
Identities = 69/213 (32%), Positives = 127/213 (59%), Gaps = 20/213 (9%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
+ R+++ +RE +E + R++Q RE Q RE + R R++ R++Q RE+E ER +
Sbjct: 377 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR-REQQLRREQQLRREQEEERHE 435
Query: 61 ERDRQRQRERETERETERQR---------ERQRQRERKRQTDRERDKDRDRERKRETDRN 111
++ Q +RE+ +RE E +R ER Q RK+Q R+++++R RER + +
Sbjct: 436 QKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEER-RERWLKLEEE 494
Query: 112 RERNRKGGRERDKQTERERDRERERQRQRERERQRQRER-----KRETDRERQRWAEREE 166
R ++ RE+ + E+E RE+ +RQ E ER +QR R +RE + R++ +REE
Sbjct: 495 ERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREE 554
Query: 167 RKK---ERKKER-KKERKEKKKEEKRREDKKRK 195
K+ ER+++R K+E++E++ + +RE+++R+
Sbjct: 555 EKRLEQERREQRLKREQEERRDQLLKREEERRQ 587
Score = 114 bits (285), Expect = 6e-26
Identities = 68/211 (32%), Positives = 123/211 (58%), Gaps = 20/211 (9%)
Query: 2 ERQRERKRETDRGKETER--ERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQ 59
E + RKRET KE E+ E + QR+RE Q E E + + R+RQ E+E+++Q
Sbjct: 242 EEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQ---EEEQQQQ 298
Query: 60 KERDRQRQRERETERETERQRERQRQRERKRQTDRERDKD--RDRERKRETDRNRE---- 113
+ R Q+ R ++ E E+Q ER+ Q+ER+ Q + R++ R++E +RE RE
Sbjct: 299 RLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEE 358
Query: 114 ------RNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREE- 166
R + R++Q RE+ RE+Q +RE++ +R+++ +RE R++ RE+
Sbjct: 359 RREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 418
Query: 167 --RKKERKKERKKERKEKKKEEKRREDKKRK 195
R+++ ++E+++ER E+K E++RRE + ++
Sbjct: 419 LRREQQLRREQEEERHEQKHEQERREQRLKR 449
Score = 112 bits (279), Expect = 3e-25
Identities = 64/201 (31%), Positives = 123/201 (61%), Gaps = 8/201 (3%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
E + +R+RE +E R+ +RQ R + E E + +QR R ++ R+ E+ RE+Q+E
Sbjct: 262 EEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQ-QQRLRREQQLRRKQEEERREQQEE 320
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
R Q++R + E E+Q R+++ R++Q RE++++R ++ R R ++ RE
Sbjct: 321 RREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRRE 380
Query: 122 ----RDKQTERERDRERERQRQRERERQRQRERKRETD--RERQRWAEREERKKERKKER 175
R++Q RE+ RE+Q +RE++ +R+++ +RE RE+Q E+EE + E+K E+
Sbjct: 381 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQ 440
Query: 176 -KKERKEKKKEEKRREDKKRK 195
++E++ K+++E+RR+ KR+
Sbjct: 441 ERREQRLKREQEERRDWLKRE 461
Score = 108 bits (271), Expect = 2e-24
Identities = 59/210 (28%), Positives = 132/210 (62%), Gaps = 16/210 (7%)
Query: 1 MERQRERKRE-TDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQ 59
++R++E +R+ R +ETER +R+++ + ++E R+R E + + ++++ RE+Q
Sbjct: 447 LKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ 506
Query: 60 KERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
R+++ +RE+ +R+ E +R +QR R ++Q RE+++ R++ KRE ++ E+ R+
Sbjct: 507 LRREQEERREQRLKRQEEEERLQQRLRS-EQQLRREQEERREQLLKREEEKRLEQERREQ 565
Query: 120 R-------ERDKQTERERDRERERQRQRERERQRQRERKRETDR-----ERQRWAEREER 167
R RD+ +RE +R ++R ++ + ER QR ++ E +R R++ +REE
Sbjct: 566 RLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEP 625
Query: 168 KKERKKE--RKKERKEKKKEEKRREDKKRK 195
++ER+++ + +E++E+++++ RRE ++R+
Sbjct: 626 EEERRQQLLKSEEQEERRQQQLRREQQERR 655
Score = 108 bits (269), Expect = 4e-24
Identities = 57/199 (28%), Positives = 123/199 (61%), Gaps = 6/199 (3%)
Query: 3 RQRERKRETDRGKETERERDRQRE-RENQTERENRHRQRD----RHRERDRQTDREKERE 57
R+RE +G+E ++++ R+R+ R Q E E R+R+ + E+ ++ + +++RE
Sbjct: 211 RRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE 270
Query: 58 RQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRK 117
Q+E ++ R+ ER+ R ++ E+Q+QR R+ Q R + ++ RE++ E +ER +
Sbjct: 271 LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQ 330
Query: 118 GGRERDKQTERERDRERERQRQRERERQRQRER-KRETDRERQRWAEREERKKERKKERK 176
R++Q RE++ RE+Q +RE+E +R+ ++ +RE + ER+ R E++ R+++ +
Sbjct: 331 QEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLR 390
Query: 177 KERKEKKKEEKRREDKKRK 195
+E++ +++++ RRE + R+
Sbjct: 391 REQQLRREQQLRREQQLRR 409
Score = 108 bits (269), Expect = 4e-24
Identities = 64/202 (31%), Positives = 119/202 (58%), Gaps = 18/202 (8%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHR--------QRDRHRERDRQTDRE 53
E++ E++R R K + ER +RE +TER + R Q + RER + + E
Sbjct: 435 EQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEE 494
Query: 54 KERERQKERDRQRQRERETERET--ERQRERQRQRERKR---QTDRERDKDRDRERKRET 108
+ RE+Q+ R++Q +RE+E RE +RQ E +R ++R R Q RE+++ R++ KRE
Sbjct: 495 ERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREE 554
Query: 109 DRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERK 168
++ E+ R R+++ +RE++ R++ +RE ER++QR ++ + +R QR E +
Sbjct: 555 EKRLEQER-----REQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVER 609
Query: 169 KERKKERKKERKEKKKEEKRRE 190
E+++ R++ K ++ EE+RR+
Sbjct: 610 LEQEERREQRLKREEPEEERRQ 631
Score = 107 bits (266), Expect = 9e-24
Identities = 62/210 (29%), Positives = 123/210 (58%), Gaps = 15/210 (7%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDR----QTDREKER 56
+ R+++ +RE +E + R+++ ER Q + R QR + + +R + + E ER
Sbjct: 407 LRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETER 466
Query: 57 ERQKERDRQRQRERETER-------ETERQRERQRQRERKRQTDRERDKDRDRERKRETD 109
Q+ R +Q +R++E ER E E +RE+Q +RE++ + ++E +++ +R+ E +
Sbjct: 467 HEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEE 526
Query: 110 RNRERNRKGGRERDKQTE-RERDRERERQRQRERERQRQRERKRETDRERQRWAEREERK 168
R ++R R + R +Q E RE+ +RE +++ E+ER+ QR ++ + +R Q EER+
Sbjct: 527 RLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERR 586
Query: 169 KERKKERKKERKE---KKKEEKRREDKKRK 195
++R K ++ER E K++E +R E ++R+
Sbjct: 587 QQRLKREQEERLEQRLKREEVERLEQEERR 616
Score = 105 bits (262), Expect = 3e-23
Identities = 72/218 (33%), Positives = 124/218 (56%), Gaps = 28/218 (12%)
Query: 5 RERKRETDRGKETERERDRQR----ERENQTERENRHRQRDRHRE-----RDRQTDREKE 55
R+R+ E + G+ ++R Q E E Q+E++ R QRDR R R RQ +E+E
Sbjct: 125 RDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQERE 184
Query: 56 RERQKERDRQRQRERETE----RETERQRE----RQRQRERKRQTDRER------DKDRD 101
R +E Q + ETE E R+RE R++ RE K+Q RER +++
Sbjct: 185 ERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEK 244
Query: 102 RERKRETDRNRERNR----KGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRE 157
RKRET +E + + R+R+ Q E E+ R+ ERQ R RERQ + ++++ RE
Sbjct: 245 EWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELR-RERQEEEQQQQRLRRE 303
Query: 158 RQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRK 195
+Q ++EE ++E+++ER+++++ ++++E+RRE + R+
Sbjct: 304 QQLRRKQEEERREQQEERREQQERREQQEERREQQLRR 341
Score = 105 bits (262), Expect = 3e-23
Identities = 63/210 (30%), Positives = 126/210 (60%), Gaps = 14/210 (6%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTEREN---RHRQRDRHRERDRQTDREKERE 57
+ R+++ +RE +E + R++Q RE Q RE R ++ +RH ++ Q RE+ +
Sbjct: 389 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLK 448
Query: 58 RQKERDRQ-RQRERETERETERQRERQ----RQRERK-RQTDRERDKDRDRERKRETDRN 111
R++E R +RE ETER + +R++Q ++ ER+ R E ++ R+++ +RE
Sbjct: 449 REQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLR 508
Query: 112 RERNRKGGRERDKQTERERDRER---ERQRQRERERQRQRERKRETDRERQRWAEREERK 168
RE+ + + +Q E ER ++R E+Q +RE+E +R++ KRE ++ ++ ER E++
Sbjct: 509 REQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQ--ERREQR 566
Query: 169 KERKKERKKERKEKKKEEKRREDKKRKWGE 198
+R++E ++++ K++EE+R++ KR+ E
Sbjct: 567 LKREQEERRDQLLKREEERRQQRLKREQEE 596
Score = 105 bits (262), Expect = 3e-23
Identities = 66/206 (32%), Positives = 125/206 (60%), Gaps = 18/206 (8%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRE--RDRQTDREKERER 58
+ R++E +R + ++ RE+ +RE+E + + R + +RH + R +Q R++E ER
Sbjct: 425 LRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEER 484
Query: 59 QK-----ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDR---DRERKRETDR 110
++ E + +R+++ E++ R++E +R++ KRQ + ER + R +++ +RE +
Sbjct: 485 RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEE 544
Query: 111 NRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRW-AEREERKK 169
RE+ K RE +K+ E+ER RE++ +RE+E +R + KRE +R +QR E+EER +
Sbjct: 545 RREQLLK--REEEKRLEQER---REQRLKREQEERRDQLLKREEERRQQRLKREQEERLE 599
Query: 170 ERKKERKKERKEKKKEEKRREDKKRK 195
+R K + ER E +EE+R + KR+
Sbjct: 600 QRLKREEVERLE--QEERREQRLKRE 623
Score = 105 bits (261), Expect = 3e-23
Identities = 63/201 (31%), Positives = 122/201 (60%), Gaps = 10/201 (4%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQT---ERENRHRQRDRHRER-DRQTDREKERE- 57
R E + ++ +G ETE D ++ R + R+ R ++ + RER DR E+E+E
Sbjct: 187 RAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEW 246
Query: 58 RQKERDRQRQRERETERETERQRERQRQRERKRQTDRE---RDKDRDRERKRETDRNRER 114
R++E +++ E+ E E +RQRE Q + E+ R+ +R+ R++ + ++++ R ++
Sbjct: 247 RKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQL 306
Query: 115 NRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKE 174
RK ER +Q E ER ++ER+ Q+E R++Q R++E RE+Q E+EE ++E++
Sbjct: 307 RRKQEEERREQQE-ERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLR 365
Query: 175 RKKERKEKKKEEKRREDKKRK 195
R++E +E+++++ RRE + R+
Sbjct: 366 REQE-EERREQQLRREQQLRR 385
Score = 104 bits (260), Expect = 4e-23
Identities = 54/194 (27%), Positives = 120/194 (61%), Gaps = 8/194 (4%)
Query: 4 QRERKRETDRGKETERERDRQRERENQT--ERENRHRQRDRHRERDRQTDREKERERQKE 61
Q E +RE E E R++Q RE Q E+E R QR + +E + + + E+Q
Sbjct: 480 QEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLR 539
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
R+++ +RE+ +RE E++ E++R+ +R + RE+++ RD+ KRE +R ++R + RE
Sbjct: 540 REQEERREQLLKREEEKRLEQERREQRLK---REQEERRDQLLKREEERRQQRLK---RE 593
Query: 122 RDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKE 181
++++ E+ RE + ++E R+++ +R+ + RQ+ + EE+++ R+++ ++E++E
Sbjct: 594 QEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQE 653
Query: 182 KKKEEKRREDKKRK 195
++++ +RE+++ +
Sbjct: 654 RREQRLKREEEEER 667
Score = 103 bits (257), Expect = 1e-22
Identities = 60/217 (27%), Positives = 125/217 (57%), Gaps = 20/217 (9%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDRE-KERERQK 60
ER+++ + E + +E E+ +RE+ + E E ++R++D ++ + Q RE +E+ R +
Sbjct: 985 EREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQ 1044
Query: 61 ERDRQRQRERETERETER----QRERQRQRERKRQTDRERDKDRDRER----KRETDRNR 112
ER+RQ + E E ++E E+ +RE +R++E +RQ +E + ++ E+ + E R +
Sbjct: 1045 ERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQ 1104
Query: 113 ERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERK 172
ER R+ E + Q E E+ ER+++R +E +RQ + E +E ++ E K+ R+
Sbjct: 1105 ERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQ 1164
Query: 173 KERKKERKE-----------KKKEEKRREDKKRKWGE 198
+ ++ R+E ++++EKRR++++R++ E
Sbjct: 1165 ELERQYREEEELQQEEEQLLREEQEKRRQERERQYRE 1201
Score = 103 bits (256), Expect = 1e-22
Identities = 61/217 (28%), Positives = 124/217 (57%), Gaps = 23/217 (10%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQR-DRHRERDRQTDREKE---RE 57
ER++ R++E +R E E ++ E+ + E E R RQ +R + + +E+E RE
Sbjct: 1127 EREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLRE 1186
Query: 58 RQKERDRQRQRERETERETERQRERQRQRERKRQTDRE-----------RD-----KDRD 101
Q++R ++R+R+ E E +RQ+ +QR R+ +++D + RD K R+
Sbjct: 1187 EQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRE 1246
Query: 102 RERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRW 161
E+ R+ + ++ R+R+ ++ +++R+RE++R+R ++R R + + +RE Q+
Sbjct: 1247 NEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKE 1306
Query: 162 AEREERKKERKKERKKERKEKKKEEKRREDKKRKWGE 198
A+R +RK + +K+ +E +E E++RR++ RK+ E
Sbjct: 1307 AKRRDRKSQEEKQLLREERE---EKRRRQETDRKFRE 1340
Score = 102 bits (255), Expect = 2e-22
Identities = 65/215 (30%), Positives = 124/215 (57%), Gaps = 27/215 (12%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
R R+ +++ ++ERDR++ER R +QRDRH + Q +RE+++E K R
Sbjct: 1259 RDRQSQQDLQHLLGEQQERDREQERR-------RWQQRDRHFPEEEQLEREEQKEA-KRR 1310
Query: 63 DRQRQRERETERETERQRERQRQRERK----------RQTDRERDKDRDRERKRETDRNR 112
DR+ Q E++ RE ++ R+++ +RK R+ R ++RDR+ + E R++
Sbjct: 1311 DRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQ 1370
Query: 113 ERNRKGGRERDKQTERERDR----ERERQRQRERERQRQRERKRETDRERQRWAEREERK 168
E+ RK E + +ER+R E ++ R +ERE+Q +++R R+ E Q+ + +E +
Sbjct: 1371 EQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDR 1430
Query: 169 KERKKE-----RKKERKEKKKEEKRREDKKRKWGE 198
K R++E +++ERK ++E++ R+++ RK+ E
Sbjct: 1431 KFREEEQQVRRQERERKFLEEEQQLRQERHRKFRE 1465
Score = 101 bits (252), Expect = 4e-22
Identities = 56/199 (28%), Positives = 117/199 (58%), Gaps = 4/199 (2%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
+ R++E +RE ++ E ER +QR R Q R + +R++ +R+ + E+ER Q+
Sbjct: 507 LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQR 566
Query: 61 -ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
+R+++ +R++ +RE ER+++R ++ + +R R + ++ +R + E R + +
Sbjct: 567 LKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPE 626
Query: 120 RERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKER 179
ER +Q + ++E RQ+Q RE+Q +RE++ + + E +R +R +R+ E ++ R++E
Sbjct: 627 EERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEER-REQEL 685
Query: 180 KEKKKEEKRREDKKR--KW 196
E+++E+ R K R KW
Sbjct: 686 AEEEQEQARERIKSRIPKW 704
Score = 101 bits (251), Expect = 5e-22
Identities = 53/221 (23%), Positives = 123/221 (55%), Gaps = 27/221 (12%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKE------ 55
++++E++RE G+E +++R +R+ Q E RQR +ER+ + E++
Sbjct: 139 QKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKG 198
Query: 56 --------------------RERQKERDRQRQRERETERETERQRERQRQRERKRQTDRE 95
R + +E +Q++RER+ E + + R+RE + + E
Sbjct: 199 HETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEE 258
Query: 96 RDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETD 155
+ ++ + +R+RE E+ RK R+ ++ +E +++++R R+ ++ R++Q E +RE
Sbjct: 259 KLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ 318
Query: 156 RERQRWAEREERKKERKKER-KKERKEKKKEEKRREDKKRK 195
ER+ ER E+++ER++++ ++E++E+++++ RRE ++ +
Sbjct: 319 EERREQQERREQQEERREQQLRREQEERREQQLRREQEEER 359
Score = 101 bits (251), Expect = 5e-22
Identities = 61/212 (28%), Positives = 119/212 (56%), Gaps = 18/212 (8%)
Query: 2 ERQRERKRETDRGKET----ERERDRQRERENQTERENRHRQRDRH---RERDRQTDREK 54
ERQ +K E + +E ERE+ R +ERE Q E +Q + ER+ + +E
Sbjct: 1017 ERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQEL 1076
Query: 55 ERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRER 114
ER+ +KE + Q++ E+ E E++R ++R+R+ + + + ++++++ +RE R +E
Sbjct: 1077 ERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQEL 1136
Query: 115 NRKGGRERDKQTERE----------RDRERERQRQRERERQRQRERKRETDRERQRWAER 164
R+ E + Q E E R +E ERQ + E E Q++ E+ ++E++R ER
Sbjct: 1137 ERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRR-QER 1195
Query: 165 EERKKERKKERKKERKEKKKEEKRREDKKRKW 196
E + +E ++ ++++RK++ ++E +R D K +W
Sbjct: 1196 ERQYREEEELQRQKRKQRYRDEDQRSDLKWQW 1227
Score = 99.8 bits (247), Expect = 1e-21
Identities = 61/215 (28%), Positives = 130/215 (60%), Gaps = 21/215 (9%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQ-RDRHRERDRQTDR-------- 52
ER++ R++E +R E + ++ E+ + ERE R RQ R+R +D++ +
Sbjct: 917 EREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGE 976
Query: 53 EKERERQKERDRQRQRERETERETER----QRERQRQRERKRQTDRERDKDRDRER---- 104
E E+ R++ER+++ + E E ++E E+ +RE++R++E +RQ ++ + ++ E+
Sbjct: 977 EPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLRE 1036
Query: 105 KRETDRNRERNRKGGRERDKQTERER--DRERERQRQRERERQRQRERKRETDRERQRWA 162
+RE R +ER R+ E + Q E E+ ERE +R++E ERQ ++E + + + E+
Sbjct: 1037 EREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLRE 1096
Query: 163 EREERKKERKKERKKERKEKKKEEKR--REDKKRK 195
E E+R+++ ++ + +E +E ++EE++ RE+++++
Sbjct: 1097 EPEKRRRQERERQCREEEELQQEEEQLLREEREKR 1131
Score = 99.4 bits (246), Expect = 2e-21
Identities = 62/210 (29%), Positives = 128/210 (60%), Gaps = 16/210 (7%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERE-NRHRQRDRHRERDRQTDREKERERQK 60
E + ++ E +E + +R ++RER+ + E E R +++ R+R+ D+++D + + E +K
Sbjct: 1172 EEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEK 1231
Query: 61 E---RDRQ-----RQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNR 112
E RD + R+ E+ + E + R+RQ Q++ + ++++DR++ER+R R+R
Sbjct: 1232 ENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDR 1291
Query: 113 ERNRKGGRERDKQTE-RERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKER 171
+ ER++Q E + RDR+ + ++Q RE + ++ R++ETDR ++ E E+ +ER
Sbjct: 1292 HFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDR---KFREEEQLLQER 1348
Query: 172 KKE--RKKERKEK-KKEEKRREDKKRKWGE 198
+++ R++ER K ++EE R +++ RK+ E
Sbjct: 1349 EEQPLRRQERDRKFREEELRHQEQGRKFLE 1378
Score = 99.0 bits (245), Expect = 2e-21
Identities = 63/211 (29%), Positives = 121/211 (57%), Gaps = 17/211 (8%)
Query: 5 RERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDR 64
R RK+E R ++ + E+ R+RE E Q + E R ++ + E+ R + + E + ER R
Sbjct: 722 RPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGR 781
Query: 65 QR---------QRERETERETERQRER-----QRQRERKRQTDRERDKDRDRERKRETDR 110
QR QRER+ E +QRE+ + ++E++R+ RER+K+ + E +
Sbjct: 782 QRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQ 841
Query: 111 NRERNRKGGRERD-KQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKK 169
RER ++ E D Q ++ER R +E++R ++ Q + ERKR + A +E+ +K
Sbjct: 842 RRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRK 901
Query: 170 ERK--KERKKERKEKKKEEKRREDKKRKWGE 198
E++ +E ++E + +++E++RR++++R++ E
Sbjct: 902 EQQLLQEEEEELQREEREKRRRQEQERQYRE 932
Score = 99.0 bits (245), Expect = 2e-21
Identities = 64/227 (28%), Positives = 129/227 (56%), Gaps = 32/227 (14%)
Query: 1 MERQRERKRETDRGKETERERDRQ------------------RERENQTERENRHRQRDR 42
++++ E+ +R K +ER+RQ E+ + ERE ++R+ +
Sbjct: 936 LQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEE 995
Query: 43 HRERDRQTDR-EKERERQKERDRQRQRERETERETER----QRERQRQRERKRQTDRERD 97
++ + Q R E+E+ R++E +RQ +++ E ++E E+ +RE++R +ER+RQ E +
Sbjct: 996 LQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEE 1055
Query: 98 KDRDRER----KRETDRNRERNRKGGRERDKQTERER--DRERERQRQRERERQRQRERK 151
++ E+ +RET R +E R+ +E + Q E E+ E E++R++ERERQ + E +
Sbjct: 1056 LQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEE 1115
Query: 152 RETDRERQRWAEREERKKERKKERKKERKEKKKEEK---RREDKKRK 195
+ + E+ ERE+R+++ + + +E +E ++EE+ R E +KR+
Sbjct: 1116 LQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRR 1162
Score = 98.6 bits (244), Expect = 3e-21
Identities = 62/209 (29%), Positives = 124/209 (59%), Gaps = 17/209 (8%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
+ QRER+ + ER++ QR + E+E R RQR R RE++ Q E+E+ +++
Sbjct: 790 LREQRERQLRAE-----ERQQREQRFLPEEEEKEQRRRQR-REREKELQFLEEEEQLQRR 843
Query: 61 ERDRQRQRERE-TERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
ER +Q Q E + + + ER+R ++++R++K + E ++ R R +E+ RK
Sbjct: 844 ERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQ 903
Query: 120 RERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKK-ERKKERKKE 178
+ ++ E + ERE++R++E+ERQ + E + + + E+ ERE+R++ ER+++ +K+
Sbjct: 904 QLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKD 963
Query: 179 RKEKKKEE---------KRREDKKRKWGE 198
+K ++KEE +RR+++++K+ E
Sbjct: 964 KKLQQKEEQLLGEEPEKRRRQEREKKYRE 992
Score = 97.4 bits (241), Expect = 7e-21
Identities = 55/198 (27%), Positives = 119/198 (60%), Gaps = 8/198 (4%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
E + E +RE +R K +E++RQ E Q ++E R+ +R RQ E+ER+ +K+
Sbjct: 908 EEEEELQRE-EREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQ---ERERQYRKD 963
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
+ Q++ E+ E E++R ++R+++ + + + ++++++ +RE R +E R+ ++
Sbjct: 964 KKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKK 1023
Query: 122 RDKQTERER--DRERERQRQRERERQRQRERKRETDRERQRWAEREERKKE--RKKERKK 177
+ Q E E+ ERE++R +ERERQ + E + + + E+ ERE R+++ ++ RK+
Sbjct: 1024 DELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKE 1083
Query: 178 ERKEKKKEEKRREDKKRK 195
E ++++E+ RE+ +++
Sbjct: 1084 EELQQEEEQLLREEPEKR 1101
Score = 97.4 bits (241), Expect = 7e-21
Identities = 59/233 (25%), Positives = 130/233 (55%), Gaps = 39/233 (16%)
Query: 2 ERQRERKRETDRGKETERERD------RQRERENQTERENRHRQRDRHRERDRQTDREK- 54
E++R ++RE +E E +++ +RE+ + E E ++R+ + ++ + Q RE+
Sbjct: 1099 EKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEP 1158
Query: 55 ERERQKERDRQRQRERETERETE---RQRERQRQRERKRQTDRERDKDRDRERKRETDRN 111
E+ R++E +RQ + E E ++E E R+ + +R++ER+RQ E + R + ++R D +
Sbjct: 1159 EKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDED 1218
Query: 112 RERNRK------------------GGRERDKQTERERDRERERQRQRERERQRQRERKRE 153
+ + K GRE ++ + E + R+RQ Q++ + +++R+
Sbjct: 1219 QRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERD 1278
Query: 154 TDRERQRWAER-----EERKKERKKERKKERKEKKKEEKR------REDKKRK 195
++ER+RW +R EE + ER+++++ +R+++K +E++ RE+K+R+
Sbjct: 1279 REQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRR 1331
Score = 97.1 bits (240), Expect = 9e-21
Identities = 54/202 (26%), Positives = 116/202 (57%), Gaps = 5/202 (2%)
Query: 2 ERQRERKRETDRGKETERER--DRQRERENQTERENRHRQRDRHRERDRQTDREKERERQ 59
E+Q R+++ R +E RE+ RQ E E +R +Q R +E R+ ++E E++
Sbjct: 498 EQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKR 557
Query: 60 KERDRQRQR-ERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKG 118
E++R+ QR +RE E ++ +R+ +R ++R + ++ R ++ E +R + R+
Sbjct: 558 LEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERR- 616
Query: 119 GRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKE 178
+R K+ E E +R ++ + E+E +RQ++ +RE R++ +REE ++ ++ K+E
Sbjct: 617 -EQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKRE 675
Query: 179 RKEKKKEEKRREDKKRKWGEGI 200
+E+++E++ E+++ + E I
Sbjct: 676 HEEERREQELAEEEQEQARERI 697
Score = 97.1 bits (240), Expect = 9e-21
Identities = 65/223 (29%), Positives = 132/223 (59%), Gaps = 28/223 (12%)
Query: 2 ERQRERKRETDRG--KETERERDRQRERENQTERENRHRQRDRH---RERDRQTDREKER 56
E QR R++E +R KE ++ R ++RE++ + +R+ + R+ ++ +ERDR+ E+++
Sbjct: 1379 EEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQ 1438
Query: 57 ERQKERDR---------QRQRERETERETERQRERQRQRERKRQTDRE--------RDKD 99
R++ER+R +++R R+ E + +ER+ Q+ +++ DR+ R ++
Sbjct: 1439 VRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQE 1498
Query: 100 RDRERKRETDRNRERNRKGGRERDKQTERERDR----ERERQRQRERERQRQRERKRETD 155
RDR+ + + R++E RK E + ++R R E ++ R++ER +QR+++R R+
Sbjct: 1499 RDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFR 1558
Query: 156 RERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGE 198
E Q EREE++ R++ +K R E++K RR++++RK+ E
Sbjct: 1559 EEEQLRQEREEQQLSRQERDRKFRLEEQK--VRRQEQERKFME 1599
Score = 96.3 bits (238), Expect = 2e-20
Identities = 55/203 (27%), Positives = 119/203 (58%), Gaps = 12/203 (5%)
Query: 2 ERQRER----KRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERE 57
E +RER + E R ++ RE+ +RE+E + E+ + ++ + ++ +++++ RE
Sbjct: 482 EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRRE 541
Query: 58 RQKERDR--QRQRERETERETERQRERQRQRERKRQ-TDRERDKDRDRERKRETDRNRER 114
+++ R++ +R+ E+ E+E QR ++ Q ER+ Q RE ++ + R ++ + +R +R
Sbjct: 542 QEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQR 601
Query: 115 NRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREER-----KK 169
++ ER +Q ER R + + + ER +Q + ++E R++Q E++ER K+
Sbjct: 602 LKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKR 661
Query: 170 ERKKERKKERKEKKKEEKRREDK 192
E ++ER ++R +++ EE+RRE +
Sbjct: 662 EEEEERLEQRLKREHEEERREQE 684
Score = 96.3 bits (238), Expect = 2e-20
Identities = 62/222 (27%), Positives = 117/222 (52%), Gaps = 27/222 (12%)
Query: 1 MERQRERKRETDRGKETERERDRQRE---RENQTERENRHRQRDRHRERDRQTDREKERE 57
+ER + +R R K E E +R+++ E Q ER + +R++ R+++ RE+E E
Sbjct: 607 VERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEE 666
Query: 58 RQKER-DRQRQRERETERETERQRERQRQRERKR----------QTDRERDKDRDRERKR 106
R ++R R+ + ER + E ++E+ R+R + R + D + K R RK+
Sbjct: 667 RLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQ 726
Query: 107 ETDRNRERNRKGGRERDKQTERERDRERERQRQRERER-----QRQRERKRETDRER--Q 159
E R R+ + R R+ + + + + RQ+Q E +R Q Q E K E R+R
Sbjct: 727 EGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSA 786
Query: 160 RWAEREERKKERKKERKKER------KEKKKEEKRREDKKRK 195
R RE+R+++ + E +++R +E++KE++RR+ ++R+
Sbjct: 787 RPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRERE 828
Score = 96.3 bits (238), Expect = 2e-20
Identities = 52/200 (26%), Positives = 120/200 (60%), Gaps = 8/200 (4%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
++ ++ R +RG++ ++RDR+ E Q +E +Q R +ERDR+ E+++ R++E+
Sbjct: 1535 QEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSR-QERDRKFRLEEQKVRRQEQ 1593
Query: 63 DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNR----ERNRKG 118
+R+ + + R E Q++ +++R+RK + D + ++R+ ++ +R+R E +
Sbjct: 1594 ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLR 1653
Query: 119 GRERDKQTERERDRERERQRQRERERQRQRERKRETD---RERQRWAEREERKKERKKER 175
+ER++Q +RDR+ + Q +E + Q+ R++E D RE ++ R+ER+++ +E
Sbjct: 1654 RQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEE 1713
Query: 176 KKERKEKKKEEKRREDKKRK 195
++ R+++ + + R E++ R+
Sbjct: 1714 QQLRRQELERKFREEEQLRQ 1733
Score = 95.5 bits (236), Expect = 3e-20
Identities = 59/213 (27%), Positives = 121/213 (56%), Gaps = 20/213 (9%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRE-------------RDR 48
ER ++ + E D +E + R Q +R +Q R +R R R +++
Sbjct: 844 ERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQ 903
Query: 49 QTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRET 108
Q +E+E E Q+E +R+++R +E ER + + E Q Q+E ++ ER+K R +ER+R+
Sbjct: 904 QLLQEEEEELQRE-EREKRRRQEQER--QYREEEQLQQEEEQLLREEREKRRRQERERQY 960
Query: 109 DRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRE---RKRETDRERQRWAERE 165
++++ +K + ++ E+ R +ERE++ + E E Q++ E R+ R RQ W ER+
Sbjct: 961 RKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEW-ERQ 1019
Query: 166 ERKKERKKERKKERKEKKKEEKRREDKKRKWGE 198
RKK+ ++ +++ +++E++R ++++R++ E
Sbjct: 1020 YRKKDELQQEEEQLLREEREKRRLQERERQYRE 1052
Score = 95.1 bits (235), Expect = 4e-20
Identities = 51/210 (24%), Positives = 124/210 (59%), Gaps = 13/210 (6%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQ-------RDRHRERDRQTDREK 54
+++ ++K E G+E E+ R ++RE++ + E E + + R++ R ++ + K
Sbjct: 963 DKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRK 1022
Query: 55 ERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRER 114
+ E Q+E ++ + ERE R ER+R+ + + E +++ ++ ++R+ R++E +R +
Sbjct: 1023 KDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRK 1082
Query: 115 NRKGGRERD----KQTERERDRERERQRQRERERQRQRER--KRETDRERQRWAEREERK 168
+ +E + ++ E+ R +ERERQ + E E Q++ E+ + E ++ R++ ER+ R+
Sbjct: 1083 EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYRE 1142
Query: 169 KERKKERKKERKEKKKEEKRREDKKRKWGE 198
+E ++ +++ ++ E++RR++ +R++ E
Sbjct: 1143 EEEVQQEEEQLLREEPEKRRRQELERQYRE 1172
Score = 94.4 bits (233), Expect = 6e-20
Identities = 59/210 (28%), Positives = 116/210 (55%), Gaps = 17/210 (8%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
ER+R +++ D+ + E +R+R R + Q + ++ ++ + E +RE +++
Sbjct: 861 ERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREK 920
Query: 62 RDRQRQRERETERETERQRERQ---RQRERKRQTDRERDKDRDRERKR----------ET 108
R RQ Q + E E +Q E Q +RE++R+ +RER +D++ ++ E
Sbjct: 921 RRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEK 980
Query: 109 DRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERK 168
R +ER +K E + Q E E+ ER+++R +E +RQ +K E +E ++ REER+
Sbjct: 981 RRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLL-REERE 1039
Query: 169 KERKKERKKERKEKKKEEKRREDKKRKWGE 198
K R +ER+++ +E EE+ ++++++ GE
Sbjct: 1040 KRRLQERERQYRE---EEELQQEEEQLLGE 1066
Score = 94.4 bits (233), Expect = 6e-20
Identities = 64/211 (30%), Positives = 127/211 (60%), Gaps = 17/211 (8%)
Query: 2 ERQRERKR-ETDRGKETERERDRQRERE--NQTERENRHRQRD-RHRERDRQTDREKERE 57
ER+ +R+R ETDR E + ++RE + + ER+ + R+ + RH+E+ R+ E++R
Sbjct: 1324 EREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRL 1383
Query: 58 RQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERK-RETD---RNRE 113
R++ER+R+ +E + R ER+++ ++ R+RK + + ++ ++R+RK RE + R +E
Sbjct: 1384 RRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQE 1443
Query: 114 RNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDR----ERQRWAEREERKK 169
R RK E ++Q +ER R+ + Q +ER+ Q+ ++E DR E Q+ +E +K
Sbjct: 1444 RERK-FLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRK 1502
Query: 170 ERKKERKKERKEKK----KEEKRREDKKRKW 196
R++E + + E+K +++ R+ ++RK+
Sbjct: 1503 FREQELRSQEPERKFLEEEQQLHRQQRQRKF 1533
Score = 94.0 bits (232), Expect = 8e-20
Identities = 50/203 (24%), Positives = 122/203 (60%), Gaps = 7/203 (3%)
Query: 1 MERQRERKRETDRGKETERERDRQ-----RERENQTERENRHRQRDRHRERDRQTDREKE 55
+E +R+R+R T K +E+ R+ +E E + +RE R ++R + +ER + + + +
Sbjct: 878 LEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQ 937
Query: 56 RERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERN 115
+E ++ +R++ R ERE + +++++ Q++ ++ E +K R +ER+++ E
Sbjct: 938 QEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQ 997
Query: 116 RKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKER 175
++ + ++ E+ R +E ERQ +++ E Q++ E+ +RE++R ERE + +E ++ +
Sbjct: 998 QEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQ 1057
Query: 176 KKERK--EKKKEEKRREDKKRKW 196
++E + +++E +RR++ +R++
Sbjct: 1058 QEEEQLLGEERETRRRQELERQY 1080
Score = 93.6 bits (231), Expect = 1e-19
Identities = 60/211 (28%), Positives = 126/211 (59%), Gaps = 18/211 (8%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQT---ERENRHRQRDRHRERDRQTDR-EKERE 57
ERQ+ +R +E E+ R ++RERE + E E + ++R+R ++ + D ++++E
Sbjct: 802 ERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQE 861
Query: 58 RQKERDRQRQRERETERETERQRER---------QRQRERKRQTDRERDKDRDRERKRET 108
R++ ++++R ++ + E ER+R R Q Q +++Q +E +++ RE +RE
Sbjct: 862 RRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQRE-EREK 920
Query: 109 DRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQ-RERKRETDRERQRWAEREER 167
R +E+ R+ E Q E E+ ER+++R +ER+RQ R+ K+ +E Q E E+
Sbjct: 921 RRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEK 980
Query: 168 KKERKKERK-KERKEKKKEEKR--REDKKRK 195
++ +++E+K +E +E ++EE++ RE+++++
Sbjct: 981 RRRQEREKKYREEEELQQEEEQLLREEREKR 1011
Score = 93.6 bits (231), Expect = 1e-19
Identities = 59/210 (28%), Positives = 121/210 (57%), Gaps = 17/210 (8%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQ-RDRHRERDRQTDREKER--ER 58
E Q+ R++E DR + R ++ ER+ E + HRQ R R ++ Q R +ER +R
Sbjct: 1490 EEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQR 1549
Query: 59 QKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKG 118
+++RDR+ + E + +E E Q+ +++R+RK + + ++ + +++ERK D + R ++G
Sbjct: 1550 RQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEG 1609
Query: 119 GRERDKQTERERDRERERQRQRERERQRQRERKRETDR---ERQRWAEREERKKERKKER 175
+Q +ERDR+ Q +ER+ Q+ ++E DR E + R+ER+++ + +R
Sbjct: 1610 ----QQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDR 1665
Query: 176 KKERKEK-------KKEEKRREDKKRKWGE 198
++ +E+ ++++ RR+++ RK+ E
Sbjct: 1666 DRKFREEEQLLQEGEEQQLRRQERDRKFRE 1695
Score = 93.6 bits (231), Expect = 1e-19
Identities = 58/204 (28%), Positives = 121/204 (59%), Gaps = 8/204 (3%)
Query: 2 ERQRERKRETDRGKETERERDRQREREN---QTERENRHRQRDRHRERDRQTDREKERE- 57
E Q+ R++E DR E ++ R++ERE Q E++ R ++ +R + Q +E E+E
Sbjct: 1680 EEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQ 1739
Query: 58 -RQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRE--RKRETDRNRER 114
R++ER R+ E + E E Q+ R+++R+RK + + + ++R+ + R +E+DR
Sbjct: 1740 LRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFRE 1799
Query: 115 NRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKE 174
+ +ER++Q R + R+ + + + E+ + ++E++ +R+RQ AE E+ + K
Sbjct: 1800 EEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAE-EQFATQEKSR 1858
Query: 175 RKKERKEKKKEEKRREDKKRKWGE 198
R+++ +++E+KRR++++RK E
Sbjct: 1859 REEQELWQEEEQKRRQERERKLRE 1882
Score = 93.2 bits (230), Expect = 1e-19
Identities = 51/204 (25%), Positives = 113/204 (55%), Gaps = 10/204 (4%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
E+Q R++E R + +RE +++ E+E + +R R ++ R + R+ +R ++R ++++
Sbjct: 535 EQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQ 594
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
+R QR + E E Q ER+ QR ++ + + ER + + ++E R ++ R+
Sbjct: 595 EERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQER 654
Query: 122 RDKQTERERDRERERQR-QRERERQRQRERKRETDRERQR---------WAEREERKKER 171
R+++ +RE + ER QR +RE E +R+ + E ++E+ R W + E + +
Sbjct: 655 REQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADA 714
Query: 172 KKERKKERKEKKKEEKRREDKKRK 195
++ + R K++ ++RR++++ K
Sbjct: 715 RQSKVYSRPRKQEGQRRRQEQEEK 738
Score = 93.2 bits (230), Expect = 1e-19
Identities = 54/221 (24%), Positives = 113/221 (51%), Gaps = 27/221 (12%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK- 60
E + ER+++ + +E E R +Q RE Q RE R ++ + +++ RE E ER++
Sbjct: 624 EPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQ 683
Query: 61 ---ERDRQRQRER----------ETERETERQRERQRQRERKRQTDRERDKDRDRERKRE 107
E ++++ RER + E E + ++ + R RK++ R R + ++ R+RE
Sbjct: 684 ELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRE 743
Query: 108 TDRNRERNRKGGRERDKQTER-------------ERDRERERQRQRERERQRQRERKRET 154
++ + + R++ ++ +R ER R+R R RE++ ++ R E
Sbjct: 744 SELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEER 803
Query: 155 DRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRK 195
+ QR+ EE K++R+++R++ KE + E+ + ++R+
Sbjct: 804 QQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRE 844
Score = 93.2 bits (230), Expect = 1e-19
Identities = 66/226 (29%), Positives = 121/226 (53%), Gaps = 31/226 (13%)
Query: 2 ERQRERKRETDRGKETERERDRQRE---------RENQTERENRHRQRDRH--------- 43
ER+R ++R+ +E + ER+ Q+E E Q RE R +R R
Sbjct: 1282 ERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREE 1341
Query: 44 ----RERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKD 99
+ER+ Q R +ER+R+ + R +E+ + E QR R+++RERK + ++ +
Sbjct: 1342 EQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRC 1401
Query: 100 RDRERKRETDRNR----ERNRKGGRERDKQTERERDRERERQRQR---ERERQRQRERKR 152
++RE++ DR+R E + +ERD++ E + R ++R+R E E+Q ++ER R
Sbjct: 1402 QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHR 1461
Query: 153 ETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGE 198
+ E Q EREE++ R++ +K +E +++ RR+++ RK+ E
Sbjct: 1462 KFREEEQLLQEREEQQLHRQERDRKFLEE--EQQLRRQERDRKFRE 1505
Score = 92.8 bits (229), Expect = 2e-19
Identities = 51/197 (25%), Positives = 113/197 (57%), Gaps = 3/197 (1%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
E Q+ ++E DR E + R++ERE Q + R R E + E+++ R++E
Sbjct: 1632 EEQQLHRQERDRKFLEEEPQLRRQEREQQLRHD---RDRKFREEEQLLQEGEEQQLRRQE 1688
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
RDR+ + E + R ER+R+ ++ ++ R+ + ER + + ++ET++ + R ++ R+
Sbjct: 1689 RDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRK 1748
Query: 122 RDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKE 181
++ + +RE ++ R++ER+R+ + E + +RE Q+ +E +K R++E+ ++ +E
Sbjct: 1749 ILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQERE 1808
Query: 182 KKKEEKRREDKKRKWGE 198
+++ ++ D K +W E
Sbjct: 1809 EQQLRPQQRDGKYRWEE 1825
Score = 91.3 bits (225), Expect = 5e-19
Identities = 67/217 (30%), Positives = 117/217 (53%), Gaps = 22/217 (10%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTE--------RENRH-RQRDRHRERDRQTD 51
++RQ+ ++R D + ++ + + E+EN REN RQ + + RDRQ+
Sbjct: 1205 LQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQ 1264
Query: 52 REKER--ERQKERDRQRQRERETERE----TERQRERQRQRERKRQTDRERDKDRD--RE 103
++ + Q+ERDR+++R R +R+ E Q ER+ Q+E KR+ DR+ +++ RE
Sbjct: 1265 QDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRR-DRKSQEEKQLLRE 1323
Query: 104 RKRETDRNRERNRKGGRERDKQTERERD--RERERQRQRERERQRQRERKRETDRERQRW 161
+ E R +E +RK E ERE R +ER R+ E R +E+ R+ E QR
Sbjct: 1324 EREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRL 1383
Query: 162 AEREERKKERKKERKKERKEKKKEEKRREDKKRKWGE 198
+E +K K+E++ +E +E++ R+D+ RK+ E
Sbjct: 1384 RRQERERKFLKEEQQLRCQE--REQQLRQDRDRKFRE 1418
Score = 90.9 bits (224), Expect = 7e-19
Identities = 70/235 (29%), Positives = 135/235 (57%), Gaps = 41/235 (17%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHR------QRDRHRERDRQ------ 49
ER ++R+++ DR K E E+ RQ E Q R+ R R Q+ R +E++R+
Sbjct: 1544 ERGQQRRQDRDR-KFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQ 1602
Query: 50 --TDREKERERQKERDRQRQRERETERETERQRERQRQRERK--------RQTDRERDKD 99
+E +++ ++ERDR+ + + + +E E Q+ +++R+RK R+ +RE+
Sbjct: 1603 QLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLR 1662
Query: 100 RDRERK-RETD-----------RNRERNRKGGRERDKQTERERDRERERQRQRERERQRQ 147
DR+RK RE + R +ER+RK RE ++Q R+ +RER+ ++ ++ R+++
Sbjct: 1663 HDRDRKFREEEQLLQEGEEQQLRRQERDRK-FREEEQQLRRQ-ERERKFLQEEQQLRRQE 1720
Query: 148 RERK-RETDRERQRWAEREERKKERKK---ERKKERKEKKKEEKRREDKKRKWGE 198
ERK RE ++ RQ + + R++ER + E ++ R E+++++ RR+++ RK+ E
Sbjct: 1721 LERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFRE 1775
Score = 90.5 bits (223), Expect = 9e-19
Identities = 55/213 (25%), Positives = 111/213 (52%), Gaps = 15/213 (7%)
Query: 1 MERQRERKRE----TDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKER 56
+ R++E +RE + K E+ER QR + Q ER ++ +R+ R + R ++ER
Sbjct: 538 LRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEER 597
Query: 57 ERQKERDRQRQRERETERETERQRERQRQRERKRQ--TDRERDKDRDRERKRETDRNRER 114
Q+ + + +R + ER +R + + + ER++Q E+++ R ++ +RE RE+
Sbjct: 598 LEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQ 657
Query: 115 NRKGGRERDK---QTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKER 171
K E ++ + +RE + ER Q E E+++ RER + + Q E E ++
Sbjct: 658 RLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQS 717
Query: 172 K------KERKKERKEKKKEEKRREDKKRKWGE 198
K K+ + R+++++E++RR + + +W E
Sbjct: 718 KVYSRPRKQEGQRRRQEQEEKRRRRESELQWQE 750
Score = 90.1 bits (222), Expect = 1e-18
Identities = 62/214 (28%), Positives = 124/214 (57%), Gaps = 21/214 (9%)
Query: 2 ERQRERKRETDRGKETER---ERDRQREREN------QTERENRHRQRDRHRERDRQTDR 52
ER R+ + + R +E ER E ++Q R+ Q E++ R ++R + R +DR
Sbjct: 1498 ERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKF 1557
Query: 53 EKERERQKERDRQR--QRERETERETERQRERQRQRERKRQTDRE--RDKDRDRERKRET 108
+E + ++ER+ Q+ ++ER+ + E Q+ R++++ERK D + R ++ ++ ++E
Sbjct: 1558 REEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQER 1617
Query: 109 DRNRERNRKGGRERDKQT--ERERDR----ERERQRQRERERQRQRERKRETDRERQRWA 162
DR + + +ER++Q +ERDR E + R++ERE+Q + +R R+ E Q
Sbjct: 1618 DRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQ 1677
Query: 163 EREERKKERKKERKKERKEKKKEEKRREDKKRKW 196
E EE++ R++ +K R+E +++ RR++++RK+
Sbjct: 1678 EGEEQQLRRQERDRKFREE--EQQLRRQERERKF 1709
Score = 89.7 bits (221), Expect = 1e-18
Identities = 52/194 (26%), Positives = 116/194 (59%), Gaps = 2/194 (1%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
ME +++ +R+ + ++ +ERDR+ + Q +E +Q R +ERDR+ E+ + R++
Sbjct: 1598 MEDEQQLRRQEGQ-QQLRQERDRKFREDEQLLQEREEQQLHR-QERDRKFLEEEPQLRRQ 1655
Query: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
ER++Q + +R+ + E Q ++ + ++ R+ +R+R + ++ R +R R+ ++ +
Sbjct: 1656 EREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQ 1715
Query: 121 ERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERK 180
R ++ ER+ E + +++ E+E+ R++ER R+ E Q EREE++ R++ +K R+
Sbjct: 1716 LRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFRE 1775
Query: 181 EKKKEEKRREDKKR 194
E++ ++R E + R
Sbjct: 1776 EEQLRQEREEQQLR 1789
Score = 89.4 bits (220), Expect = 2e-18
Identities = 58/221 (26%), Positives = 116/221 (52%), Gaps = 28/221 (12%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQT----DREKERER 58
RQ+ KRE + E +R+ E + RE R ++ + ER +Q ++E+ R++
Sbjct: 586 RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQ 645
Query: 59 QKERDRQRQRERETERETERQR-----ERQRQRERKRQTDRERDKDRDRERKR------- 106
Q R++Q +RE+ +RE E +R +R+ + ER+ Q E ++++ RER +
Sbjct: 646 QLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQ 705
Query: 107 ---ETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERK--RETDRERQRW 161
E++ + +++ R R ++ +R R + E++R+RE E Q Q E + R+ E QR
Sbjct: 706 WQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRR 765
Query: 162 AEREERKKERKKERKKER-------KEKKKEEKRREDKKRK 195
+ + E K ER ++R +E+++ + R E+++++
Sbjct: 766 DFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQR 806
Score = 89.4 bits (220), Expect = 2e-18
Identities = 63/229 (27%), Positives = 129/229 (56%), Gaps = 32/229 (13%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHR----------------- 44
E Q+ ++E DR E ++ R++ERE + E + +++RHR
Sbjct: 1419 EEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQL 1478
Query: 45 ---ERDRQTDREKERERQKERDR----QRQRERETER---ETERQRER-QRQRERKRQTD 93
ERDR+ E+++ R++ERDR Q R +E ER E E+Q R QRQR+ ++
Sbjct: 1479 HRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQ 1538
Query: 94 RERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRE 153
+ R ++R ++R+++ DR + +ER++Q ++R+R+ + + ++ R++++ERK
Sbjct: 1539 QLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFM 1598
Query: 154 TDRERQRWAEREE--RKKERKKERKKER--KEKKKEEKRREDKKRKWGE 198
D ++ R E ++ R++ +K R+ E+ +E+++++ R+++ RK+ E
Sbjct: 1599 EDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLE 1647
Score = 89.4 bits (220), Expect = 2e-18
Identities = 64/212 (30%), Positives = 125/212 (58%), Gaps = 18/212 (8%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENR--HRQ-RDRHRERDRQTDREKERER 58
+ Q+ R++E + ER+R + + + ERE + HRQ RDR + R +ERE+
Sbjct: 1600 DEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQ 1659
Query: 59 Q--KERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERK----RETDRNR 112
Q +RDR+ + E + +E E Q+ R+++R+RK + + ++ + ++RERK + R +
Sbjct: 1660 QLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQ 1719
Query: 113 ERNRKGGRERD--KQTERERDRERERQR------QRERERQRQRERKRETDRE-RQRWAE 163
E RK E ++TE+E+ R +ER R Q ER+ Q+ R++E DR+ R+
Sbjct: 1720 ELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQL 1779
Query: 164 REERKKERKKERKKERKEKKKEEKRREDKKRK 195
R+ER++++ + ++ +RK +++E+ R+E ++++
Sbjct: 1780 RQEREEQQLRSQESDRKFREEEQLRQEREEQQ 1811
Score = 89.0 bits (219), Expect = 3e-18
Identities = 59/203 (29%), Positives = 114/203 (56%), Gaps = 13/203 (6%)
Query: 1 MERQRERKRETDRGKETERERDR-QRERENQTERENRHRQRDRHRERDRQTDREKERERQ 59
++R++E +R+ +E ER + R +RE+E + E+ + + +R + +R+ R K E +
Sbjct: 567 LKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPE 626
Query: 60 KERDRQRQRERETERETERQRERQRQRERKRQ-TDRERDKDRDRER-KRETDRNRERNRK 117
+ER RQ+ + E + E +Q+ R+ Q+ER+ Q RE +++R +R KRE + R
Sbjct: 627 EER-RQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQEL 685
Query: 118 GGRERDKQTERERDRERERQRQRERERQRQ------RERKRETDRERQRWAEREERKKER 171
E+++ ER + R + Q Q E E + R RK+E R RQ E+EE+++ R
Sbjct: 686 AEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQ---EQEEKRRRR 742
Query: 172 KKERKKERKEKKKEEKRREDKKR 194
+ E + + +E+ +++ E+++R
Sbjct: 743 ESELQWQEEERAHRQQQEEEQRR 765
Score = 87.8 bits (216), Expect = 6e-18
Identities = 66/241 (27%), Positives = 131/241 (54%), Gaps = 47/241 (19%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
E Q ER+++ R ++ ER R+++ +RE + ER + +R+ ER Q E+E+E+ +E
Sbjct: 637 EEQEERRQQQLRREQQER-REQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARE 695
Query: 62 RDRQR------QRERETE----------RETERQRERQRQRERKRQTDRE---RDKDRDR 102
R + R Q E E + R+ E QR RQ Q E++R+ + E ++++R
Sbjct: 696 RIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAH 755
Query: 103 ERKRETDRNR--------ERNRKGGRER-----DKQTERERD-RERERQRQRER------ 142
+++E ++ R E + GR+R + +RER R ERQ++ +R
Sbjct: 756 RQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEE 815
Query: 143 ERQRQRERKRETDRERQRWAEREE-RKKERKKERKKER------KEKKKEEKRREDKKRK 195
E++++R ++RE ++E Q E E+ +++ER ++ ++E +E+++ +++R D+K +
Sbjct: 816 EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWR 875
Query: 196 W 196
W
Sbjct: 876 W 876
Score = 87.4 bits (215), Expect = 7e-18
Identities = 53/199 (26%), Positives = 118/199 (59%), Gaps = 10/199 (5%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
E Q+ R++E +R K E E+ RQ + Q R+ R+R+ E + +RE+++ R++E
Sbjct: 1712 EEQQLRRQELER-KFREEEQLRQETEQEQLRRQERYRKI--LEEEQLRPEREEQQLRRQE 1768
Query: 62 RDRQRQRERETERETERQRERQRQRERK----RQTDRERDKDRDRERKRETDRNRERNRK 117
RDR+ + E + +E E Q+ R ++ +RK Q +ER++ + R ++R+ E +
Sbjct: 1769 RDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQL 1828
Query: 118 GGRERDKQTERERDRERERQRQ---RERERQRQRERKRETDRERQRWAEREERKKERKKE 174
E++++ +ERDR+ + Q +E+ R+ ++E +E +++R++ ER+ R++ +++
Sbjct: 1829 QLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQ 1888
Query: 175 RKKERKEKKKEEKRREDKK 193
+K+E++ ++ E + ++ K
Sbjct: 1889 QKEEQRHRQVGEIKSQEGK 1907
Score = 84.3 bits (207), Expect = 6e-17
Identities = 57/230 (24%), Positives = 121/230 (52%), Gaps = 35/230 (15%)
Query: 3 RQRERK--------RETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREK 54
++R+RK R +R ++ +RDR+ E Q +E +Q R +ERDR+ E+
Sbjct: 1639 QERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQL-RRQERDRKFREEE 1697
Query: 55 ERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERK----RETDR 110
++ R++ER+R+ +E + R E +R+ + + + +++T++E+ + ++R RK +
Sbjct: 1698 QQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRP 1757
Query: 111 NRERNRKGGRERDKQTERE----RDRERERQRQRERERQRQRERKRETDRERQ------- 159
RE + +ERD++ E ++RE ++ R +E +R+ + E + +RE Q
Sbjct: 1758 EREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQR 1817
Query: 160 ----RWAEREERKKERKKERKKERKEKKK-------EEKRREDKKRKWGE 198
RW E + + +E+++ ++ER + + +EK R +++ W E
Sbjct: 1818 DGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQE 1867
Score = 82.8 bits (203), Expect = 2e-16
Identities = 62/208 (29%), Positives = 112/208 (53%), Gaps = 31/208 (14%)
Query: 18 ERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETE 77
E +R R +E+ + + + R RDRQ + E + R+++R Q + E E ++E
Sbjct: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE 156
Query: 78 RQRERQRQRERKRQTD---RERDKDRDRERKR------------ETD--------RNRE- 113
+Q ER QR+R+R+ + R+R + ++RE +R ET+ R RE
Sbjct: 157 KQ-ERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRREL 215
Query: 114 -RNRKGGRERDKQTERERD----RERERQRQRERERQRQRERKRETDRERQRWAE-REER 167
R+ GRE +Q RER +E E + R+RE ++E ++ + E QR E +EE
Sbjct: 216 LELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEE 275
Query: 168 KKERKKERKKERKEKKKEEKRREDKKRK 195
++ RK ER++ R+E+++EE++++ +R+
Sbjct: 276 EQLRKLERQELRRERQEEEQQQQRLRRE 303
Score = 81.3 bits (199), Expect = 5e-16
Identities = 59/213 (27%), Positives = 108/213 (50%), Gaps = 24/213 (11%)
Query: 1 MERQRERKRETDRGKETERERDRQREREN------QTERENRHRQ-----RDRHRERDRQ 49
++R+ E +R E E+E+ R+R + Q E E RQ R R +E R+
Sbjct: 672 LKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRR 731
Query: 50 TDREKERERQKERDRQRQRERETERETERQRER-----QRQRERKRQTDRERDKDRD--R 102
++E+ R++E + Q Q E R+ + + +R Q Q E K + R+R R R
Sbjct: 732 RQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLR 791
Query: 103 ERKRETDRNRERNRKGGR----ERDKQTERERDRERERQRQ--RERERQRQRERKRETDR 156
E++ R ER ++ R E +K+ R + RERE++ Q E E+ ++RER ++
Sbjct: 792 EQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQE 851
Query: 157 ERQRWAEREERKKERKKERKKERKEKKKEEKRR 189
E E +ER++ +++ R ++ + + +EE++R
Sbjct: 852 EEDGLQEDQERRRSQEQRRDQKWRWQLEEERKR 884
Score = 76.6 bits (187), Expect = 1e-14
Identities = 52/165 (31%), Positives = 96/165 (58%), Gaps = 11/165 (6%)
Query: 40 RDRHRERDRQTDREKERERQKERDRQRQRER--ETERETERQRERQRQRERKRQTDRERD 97
+DR +E D++ ++R+ ++E QR+R++ E ERE E+ ++ER Q DR+R
Sbjct: 111 QDRRQEEDQRRFEPRDRQLEEEPG-QRRRQKRQEQERELAEGEEQSEKQERLEQRDRQR- 168
Query: 98 KDRDRERKRETDRNRERNRKGGRE----RDKQTERERDRERERQRQRERERQRQRERKRE 153
+D + R+R+ + RE R + + +TE D E+ R+R+ R++ RE K++
Sbjct: 169 RDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQ 228
Query: 154 TDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGE 198
RERQ +R +++E K+ RK+E +K+EEK +E++ ++ E
Sbjct: 229 QRRERQ---DRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE 270
Score = 54.7 bits (130), Expect = 5e-08
Identities = 37/132 (28%), Positives = 74/132 (56%), Gaps = 18/132 (13%)
Query: 4 QRERKRETDRGKETERE-RDRQRERENQTERENRHRQRD---RHRERDRQTDREKERERQ 59
++ER+ + R +E++R+ R+ ++ R+ + E++ R +QRD R E Q + +++R RQ
Sbjct: 1780 RQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQ 1839
Query: 60 KERDRQ-------------RQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKR 106
ERDRQ R+ E+E +E E++R ++R+R+ + + R + K+ R R+
Sbjct: 1840 -ERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQV 1898
Query: 107 ETDRNRERNRKG 118
+++E G
Sbjct: 1899 GEIKSQEGKGHG 1910
Score = 44.7 bits (104), Expect = 5e-05
Identities = 28/103 (27%), Positives = 58/103 (56%), Gaps = 7/103 (6%)
Query: 93 DRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKR 152
D E+ D + DR +E +++ RD+Q E E +R RQ+++E+ER+ ++
Sbjct: 96 DEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPG-QRRRQKRQEQERELAEGEEQ 154
Query: 153 ETDRERQRWAEREERKKERKKERK-KERKEKKKEEKRREDKKR 194
+ER E+R ++R+ E ++R+E ++ E+RR ++++
Sbjct: 155 SEKQERL-----EQRDRQRRDEELWRQRQEWQEREERRAEEEQ 192
Score = 40.8 bits (94), Expect = 8e-04
Identities = 29/90 (32%), Positives = 56/90 (62%), Gaps = 10/90 (11%)
Query: 113 ERNRKGGRE---RDKQTERERDRERERQRQRERER-QRQRERKRETDRERQRWAEREERK 168
+R R G+E +D++ E ++ R R RQ E E QR+R++++E +RE AE EE+
Sbjct: 99 KRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQEREL---AEGEEQS 155
Query: 169 KERKKERKKERKEKKKEEKRREDKKRKWGE 198
+ K+ER ++R ++++E+ ++++W E
Sbjct: 156 E--KQERLEQRDRQRRDEELWR-QRQEWQE 182
Score = 40.8 bits (94), Expect = 8e-04
Identities = 19/75 (25%), Positives = 45/75 (60%), Gaps = 7/75 (9%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
+E Q +R R+ ER+R + E + T+ ++R +++ +E +++ +E+ER+ ++
Sbjct: 1830 LEEQEQRLRQ-------ERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLRE 1882
Query: 61 ERDRQRQRERETERE 75
E R++Q+E + R+
Sbjct: 1883 EHIRRQQKEEQRHRQ 1897
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 121 bits (303), Expect = 5e-28
Identities = 70/194 (36%), Positives = 105/194 (54%), Gaps = 18/194 (9%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
E+ R+R E DR + ++E+ + ERE + ERE R+R R RE + +REKER R +E
Sbjct: 232 EKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEE---EREKERARDRE 288
Query: 62 -RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
R R R R R + R ++R+ R R +R R +R R + RDR R R DR+ ++R
Sbjct: 289 RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHR---- 344
Query: 121 ERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKER-KKER 179
R RDR R + R R+ + R + R RE DR+ + E+E+R + KK K
Sbjct: 345 ------SRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSK---EKEKRGSDDKKSSVKSGS 395
Query: 180 KEKKKEEKRREDKK 193
+EK+ E+ E K+
Sbjct: 396 REKQSEDTNTESKE 409
Score = 115 bits (287), Expect = 3e-26
Identities = 63/166 (37%), Positives = 104/166 (62%), Gaps = 6/166 (3%)
Query: 31 TERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKR 90
T E + + R R E DR +KE++ ++ER+++R+RERE ERE +R+RE + +RE++R
Sbjct: 226 TVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERERERE-ERERKRRRE-EEEREKER 283
Query: 91 QTDRERDKDRDRERKRETDRNRER--NRKGGRERDKQTERERDRERERQRQRERERQRQR 148
DRER K R R R R + R +R +R +R + ER R R R+R+R R +R ++
Sbjct: 284 ARDRERRK-RSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERK 342
Query: 149 ERKRETDRERQRWAEREERK-KERKKERKKERKEKKKEEKRREDKK 193
R R DR R + +R+ K + + ++R+++RK K+KE++ +DKK
Sbjct: 343 HRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKK 388
Score = 114 bits (286), Expect = 4e-26
Identities = 65/180 (36%), Positives = 106/180 (58%), Gaps = 11/180 (6%)
Query: 18 ERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETE 77
E +++ R+R + +R+ R ++ + RE +R+ +RE+ERE ER+R+R+RE E ERE E
Sbjct: 228 EELKEKLRKRTEEPDRDERLKKEKQERE-EREKERERERE---ERERKRRREEE-EREKE 282
Query: 78 RQRERQ-RQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERER 136
R R+R+ R+R R R R DR R R+ R+R R R+ R RD++ R DR +
Sbjct: 283 RARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERK 342
Query: 137 QRQRERERQRQRERKRETDRERQRWAEREERKKERKKER-----KKERKEKKKEEKRRED 191
R R R+R+R + R R++ + R + +RE+ +K ++KE+ KK + EK+ ED
Sbjct: 343 HRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSED 402
Score = 110 bits (274), Expect = 1e-24
Identities = 56/189 (29%), Positives = 98/189 (51%), Gaps = 2/189 (1%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
E R+ + + ++ + ERE++R+RERE + ER+ R + +R +ER R +R K R R +
Sbjct: 240 EPDRDERLKKEKQEREEREKEREREREER-ERKRRREEEEREKERARDRERRK-RSRSRS 297
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
R R +R R + +R R R+R R R DR R + DR ++ R+R+R R R+
Sbjct: 298 RHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRD 357
Query: 122 RDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKE 181
R R + R+RE+ R+ + + +R + K+ + + R + E+ E K+ K
Sbjct: 358 RKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVN 417
Query: 182 KKKEEKRRE 190
E+ + E
Sbjct: 418 GTSEDIKSE 426
Score = 73.6 bits (179), Expect = 1e-13
Identities = 41/141 (29%), Positives = 73/141 (51%), Gaps = 10/141 (7%)
Query: 64 RQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERD 123
+Q + + E +E+ R+R + D K++ +RE +R RER + + R
Sbjct: 215 KQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRR 274
Query: 124 KQTERERDRERERQRQRERERQRQRERKRETDR--------ERQRWAE-REERKKERKKE 174
++ ERE++R R+R+R R+R R R R R +DR +R R E R R ++R++
Sbjct: 275 EEEEREKERARDRER-RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRS 333
Query: 175 RKKERKEKKKEEKRREDKKRK 195
R +R E+K + R+ ++ K
Sbjct: 334 RSHDRSERKHRSRSRDRRRSK 354
Score = 65.5 bits (158), Expect = 3e-11
Identities = 31/118 (26%), Positives = 64/118 (54%), Gaps = 1/118 (0%)
Query: 3 RQRERKRETDRGKETERERDRQREREN-QTERENRHRQRDRHRERDRQTDREKERERQKE 61
R R+ KR R + R RDR+R R + ++ER++R R RDR R + R K R + ++
Sbjct: 310 RSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRD 369
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
R++ R+ + + +R ++ ++ + R++Q++ + ++ + K E + E + G
Sbjct: 370 REQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEG 427
Score = 52.4 bits (124), Expect = 3e-07
Identities = 22/92 (23%), Positives = 54/92 (58%)
Query: 104 RKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAE 163
+ R D + G + E +++ R+R + +R+ + ++E++ +RE++R E
Sbjct: 205 QSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERERE 264
Query: 164 REERKKERKKERKKERKEKKKEEKRREDKKRK 195
REER+++R++E ++ KE+ ++ +RR+ + +
Sbjct: 265 REERERKRRREEEEREKERARDRERRKRSRSR 296
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 121 bits (303), Expect = 5e-28
Identities = 70/194 (36%), Positives = 105/194 (54%), Gaps = 18/194 (9%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
E+ R+R E DR + ++E+ + ERE + ERE R+R R RE + +REKER R +E
Sbjct: 232 EKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEE---EREKERARDRE 288
Query: 62 -RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
R R R R R + R ++R+ R R +R R +R R + RDR R R DR+ ++R
Sbjct: 289 RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHR---- 344
Query: 121 ERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKER-KKER 179
R RDR R + R R+ + R + R RE DR+ + E+E+R + KK K
Sbjct: 345 ------SRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSK---EKEKRGSDDKKSSVKSGS 395
Query: 180 KEKKKEEKRREDKK 193
+EK+ E+ E K+
Sbjct: 396 REKQSEDTNTESKE 409
Score = 115 bits (287), Expect = 3e-26
Identities = 63/166 (37%), Positives = 104/166 (62%), Gaps = 6/166 (3%)
Query: 31 TERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKR 90
T E + + R R E DR +KE++ ++ER+++R+RERE ERE +R+RE + +RE++R
Sbjct: 226 TVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERERERE-ERERKRRRE-EEEREKER 283
Query: 91 QTDRERDKDRDRERKRETDRNRER--NRKGGRERDKQTERERDRERERQRQRERERQRQR 148
DRER K R R R R + R +R +R +R + ER R R R+R+R R +R ++
Sbjct: 284 ARDRERRK-RSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERK 342
Query: 149 ERKRETDRERQRWAEREERK-KERKKERKKERKEKKKEEKRREDKK 193
R R DR R + +R+ K + + ++R+++RK K+KE++ +DKK
Sbjct: 343 HRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKK 388
Score = 114 bits (286), Expect = 4e-26
Identities = 65/180 (36%), Positives = 106/180 (58%), Gaps = 11/180 (6%)
Query: 18 ERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETE 77
E +++ R+R + +R+ R ++ + RE +R+ +RE+ERE ER+R+R+RE E ERE E
Sbjct: 228 EELKEKLRKRTEEPDRDERLKKEKQERE-EREKERERERE---ERERKRRREEE-EREKE 282
Query: 78 RQRERQ-RQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERER 136
R R+R+ R+R R R R DR R R+ R+R R R+ R RD++ R DR +
Sbjct: 283 RARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERK 342
Query: 137 QRQRERERQRQRERKRETDRERQRWAEREERKKERKKER-----KKERKEKKKEEKRRED 191
R R R+R+R + R R++ + R + +RE+ +K ++KE+ KK + EK+ ED
Sbjct: 343 HRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSED 402
Score = 110 bits (274), Expect = 1e-24
Identities = 56/189 (29%), Positives = 98/189 (51%), Gaps = 2/189 (1%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
E R+ + + ++ + ERE++R+RERE + ER+ R + +R +ER R +R K R R +
Sbjct: 240 EPDRDERLKKEKQEREEREKEREREREER-ERKRRREEEEREKERARDRERRK-RSRSRS 297
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
R R +R R + +R R R+R R R DR R + DR ++ R+R+R R R+
Sbjct: 298 RHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRD 357
Query: 122 RDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKE 181
R R + R+RE+ R+ + + +R + K+ + + R + E+ E K+ K
Sbjct: 358 RKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVN 417
Query: 182 KKKEEKRRE 190
E+ + E
Sbjct: 418 GTSEDIKSE 426
Score = 73.6 bits (179), Expect = 1e-13
Identities = 41/141 (29%), Positives = 73/141 (51%), Gaps = 10/141 (7%)
Query: 64 RQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERD 123
+Q + + E +E+ R+R + D K++ +RE +R RER + + R
Sbjct: 215 KQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRR 274
Query: 124 KQTERERDRERERQRQRERERQRQRERKRETDR--------ERQRWAE-REERKKERKKE 174
++ ERE++R R+R+R R+R R R R R +DR +R R E R R ++R++
Sbjct: 275 EEEEREKERARDRER-RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRS 333
Query: 175 RKKERKEKKKEEKRREDKKRK 195
R +R E+K + R+ ++ K
Sbjct: 334 RSHDRSERKHRSRSRDRRRSK 354
Score = 65.5 bits (158), Expect = 3e-11
Identities = 31/118 (26%), Positives = 64/118 (54%), Gaps = 1/118 (0%)
Query: 3 RQRERKRETDRGKETERERDRQREREN-QTERENRHRQRDRHRERDRQTDREKERERQKE 61
R R+ KR R + R RDR+R R + ++ER++R R RDR R + R K R + ++
Sbjct: 310 RSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRD 369
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
R++ R+ + + +R ++ ++ + R++Q++ + ++ + K E + E + G
Sbjct: 370 REQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEG 427
Score = 52.4 bits (124), Expect = 3e-07
Identities = 22/92 (23%), Positives = 54/92 (58%)
Query: 104 RKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAE 163
+ R D + G + E +++ R+R + +R+ + ++E++ +RE++R E
Sbjct: 205 QSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERERE 264
Query: 164 REERKKERKKERKKERKEKKKEEKRREDKKRK 195
REER+++R++E ++ KE+ ++ +RR+ + +
Sbjct: 265 REERERKRRREEEEREKERARDRERRKRSRSR 296
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 111 bits (278), Expect = 4e-25
Identities = 68/221 (30%), Positives = 109/221 (49%), Gaps = 37/221 (16%)
Query: 3 RQRERKRETDRGKETERERDRQRE--RENQTERENRHRQRDRHRERDRQTDREKERERQK 60
R RERKR++D R R R +E R ++ ++ + + H +++ +D+ +ER
Sbjct: 46 RSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSS 105
Query: 61 ER--DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKG 118
E DR +++ER++ R R R R+R R R RER K R R R+R+ R+R R RK
Sbjct: 106 ENGEDRHKRKERKSSRGRSHSRSRSRER-RHRSRSRERKKSRSRSRERKKSRSRSRERKK 164
Query: 119 GRERDKQTERE-------RDRERERQRQRERERQRQRERKRETDRER------------- 158
R R ++ +R R R R R R R R R R R+RK+ ++ R
Sbjct: 165 SRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPP 224
Query: 159 ------------QRWAEREERKKERKKERKKERKEKKKEEK 187
+ A R ER K+ +++R+KE EK+K+++
Sbjct: 225 PFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 265
Score = 104 bits (259), Expect = 6e-23
Identities = 58/208 (27%), Positives = 109/208 (52%), Gaps = 24/208 (11%)
Query: 15 KETERERDRQRERE--NQTERENRH---RQRDRHRERDRQTDREKERERQKERDRQRQRE 69
++T +RD+++E+ + + R ++H R R R RER R++D E + R + R ++ +R
Sbjct: 14 EKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRH 73
Query: 70 RETERETERQR-------ERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRER 122
++ +++ + E + R+R E +DR + ++R++ R R +R RER
Sbjct: 74 ESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER 133
Query: 123 DKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKER--- 179
R R RER++ R R RER++ R R RE + R R ER+ R + R + R + R
Sbjct: 134 ---RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRT 190
Query: 180 ------KEKKKEEKRREDKKRKWGEGIS 201
+ + ++ K+R +K R++ +S
Sbjct: 191 RSRSRTRSRSRDRKKRIEKPRRFSRSLS 218
Score = 84.0 bits (206), Expect = 8e-17
Identities = 53/170 (31%), Positives = 79/170 (46%), Gaps = 21/170 (12%)
Query: 45 ERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRER 104
ERD + +R K++++ + R R R RERKR++D E K R R R
Sbjct: 7 ERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSR 66
Query: 105 KRETDRNRERNRKG-----------------GRERDKQTERERDRERERQRQRERERQRQ 147
+E R+ +++ GRER +E DR + ++R+ R R
Sbjct: 67 SKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 126
Query: 148 RERKRETDRERQRWAEREE---RKKERKKERKKERKEKKKEEKRREDKKR 194
R R RE R R R ER++ R +ERKK R + R+ KK + RE K+R
Sbjct: 127 RSRSRER-RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRR 175
Score = 70.9 bits (172), Expect = 7e-13
Identities = 42/161 (26%), Positives = 74/161 (45%), Gaps = 16/161 (9%)
Query: 50 TDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETD 109
+D E++ ++ R +++E + R + R R RER + D E ++
Sbjct: 4 SDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRS 63
Query: 110 RNRERNRKGGRERDK-----QTERERDRERERQRQRER--------ERQRQRERKRETDR 156
R+R + + +DK ++E D+E + RER +R +++ERK R
Sbjct: 64 RSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR 123
Query: 157 ERQRWAEREERKKERKKERKKER---KEKKKEEKRREDKKR 194
R RE R + R +ERKK R +E+KK R ++K+
Sbjct: 124 SHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKK 164
Score = 47.4 bits (111), Expect = 8e-06
Identities = 30/118 (25%), Positives = 53/118 (44%), Gaps = 3/118 (2%)
Query: 87 ERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQR 146
ER + DRD+++++ R K R + RER R+ + + ++ R R R
Sbjct: 7 ERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSR 66
Query: 147 QRERKR--ETDRERQRWAEREERKKERKKERKKER-KEKKKEEKRREDKKRKWGEGIS 201
+E +R D+ ++ E KE ++ +ER + E R + K+RK G S
Sbjct: 67 SKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRS 124
>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
Length = 2240
Score = 110 bits (274), Expect = 1e-24
Identities = 65/182 (35%), Positives = 95/182 (52%), Gaps = 8/182 (4%)
Query: 13 RGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREK---ERERQKERDRQRQRE 69
+G E + + RE + R RER +EK E + Q R+RE
Sbjct: 2057 QGPEADGQWASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRE 2116
Query: 70 RETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERE 129
RE R R+R+ R RE R D++ +D DR R+R +R+RER G+E D+ ER
Sbjct: 2117 RERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERS 2176
Query: 130 RDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRR 189
R+RERER R+R+R+R R RER R+ R+R+R +R++R K K+ ++ K E R
Sbjct: 2177 RNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKS-----KESARDPKPEASRA 2231
Query: 190 ED 191
D
Sbjct: 2232 SD 2233
Score = 103 bits (258), Expect = 8e-23
Identities = 56/159 (35%), Positives = 92/159 (57%), Gaps = 5/159 (3%)
Query: 6 ERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQ 65
E + +T G++ ER +E+ + DR RER+R + +ER+ + R+
Sbjct: 2077 EYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWD 2136
Query: 66 RQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQ 125
R R++++ R+ +R RER R+R+R+ DR ++ DR RER RNRER R R+RD+
Sbjct: 2137 RHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRER----SRNRERERDRRRDRDRS 2192
Query: 126 TERERDRERERQRQRERERQRQRERKRETDRERQRWAER 164
RERDR++ R R+R R+R + R + +E+ R+ + A R
Sbjct: 2193 RSRERDRDKARDRERGRDR-KDRSKSKESARDPKPEASR 2230
Score = 101 bits (252), Expect = 4e-22
Identities = 62/158 (39%), Positives = 91/158 (57%), Gaps = 5/158 (3%)
Query: 38 RQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERD 97
R+ H R+ QT ++RER +++ E E + + +R+R+RER R RERD
Sbjct: 2071 REGKGHEYRN-QTFEGRQRERFDVGPKEKPLE-EPDAQGRASEDRRRERERGRNWSRERD 2128
Query: 98 KDRDRE--RKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETD 155
DR RE R R+ D +R+ +R R ++ ERE DR +E R RER R R+RER R D
Sbjct: 2129 WDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRD 2188
Query: 156 RERQRWAEREERKKERKKERKKERKEKKKEEKRREDKK 193
R+R R ER +R K R +ER ++RK++ K ++ D K
Sbjct: 2189 RDRSRSRER-DRDKARDRERGRDRKDRSKSKESARDPK 2225
Score = 95.5 bits (236), Expect = 3e-20
Identities = 57/154 (37%), Positives = 85/154 (55%), Gaps = 9/154 (5%)
Query: 5 RERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE--R 62
R+R+R KE E + R ++ R R R R+ RERD RE +R R K+ R
Sbjct: 2086 RQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSR 2145
Query: 63 DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRER 122
D R RER R+ ER+ +R ++ +R R+ R R+++RDR R R+ R+RE R+R
Sbjct: 2146 DWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRE------RDR 2199
Query: 123 DKQTERERDRER-ERQRQRERERQRQRERKRETD 155
DK +RER R+R +R + +E R + E R +D
Sbjct: 2200 DKARDRERGRDRKDRSKSKESARDPKPEASRASD 2233
Score = 89.7 bits (221), Expect = 1e-18
Identities = 48/129 (37%), Positives = 73/129 (56%), Gaps = 16/129 (12%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
R R+R+ DR +E +R RD+ R+ DR+RER DRE+E +R KE
Sbjct: 2121 RNWSRERDWDRPREWDRHRDKDSSRD-----------WDRNRERSANRDREREADRGKEW 2169
Query: 63 DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRER 122
DR R+R R ERE +R+R+R R R R+R D+ RD++R R+RK +R ++++ R+
Sbjct: 2170 DRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRK-----DRSKSKESARDP 2224
Query: 123 DKQTERERD 131
+ R D
Sbjct: 2225 KPEASRASD 2233
Score = 78.6 bits (192), Expect = 3e-15
Identities = 44/109 (40%), Positives = 65/109 (59%), Gaps = 8/109 (7%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
+R RE R D K++ R+ DR RER +RE R+ DR +E DR +R + RER+++
Sbjct: 2130 DRPREWDRHRD--KDSSRDWDRNRERSANRDRE---READRGKEWDRSRERSRNRERERD 2184
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDR 110
R R R R R ER+ ++ R+R+R R+RK DR + K+ R+ K E R
Sbjct: 2185 RRRDRDRSRSRERDRDKARDRERGRDRK---DRSKSKESARDPKPEASR 2230
Score = 50.4 bits (119), Expect = 1e-06
Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 19/114 (16%)
Query: 100 RDRERKRETDRNRERNRKGGRERDKQTE-----------RERDRERERQRQRERERQRQR 148
+ E + +T R+R R ++K E R R+RER R RER+ R R
Sbjct: 2074 KGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPR 2133
Query: 149 ERKRETDRERQR-WAEREERKKERKKERKKER-------KEKKKEEKRREDKKR 194
E R D++ R W ER R +ER+ +R +E+ + +R D++R
Sbjct: 2134 EWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRR 2187
Score = 50.1 bits (118), Expect = 1e-06
Identities = 30/77 (38%), Positives = 44/77 (57%), Gaps = 4/77 (5%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
++ +R RE R +E ER+R R R+R ER+ R + RDR R RDR+ DR K +E R
Sbjct: 2167 KEWDRSRERSRNRERERDRRRDRDRSRSRERD-RDKARDRERGRDRK-DRSKSKE--SAR 2222
Query: 63 DRQRQRERETERETERQ 79
D + + R ++ T Q
Sbjct: 2223 DPKPEASRASDAGTASQ 2239
Score = 47.4 bits (111), Expect = 8e-06
Identities = 20/60 (33%), Positives = 35/60 (58%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
ER R R+RE DR ++ +R R R+R+R+ +RE ++DR + ++ D + E R +
Sbjct: 2174 ERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRASD 2233
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 108 bits (270), Expect = 3e-24
Identities = 55/194 (28%), Positives = 118/194 (60%), Gaps = 7/194 (3%)
Query: 4 QRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERD 63
++ R+++++ ER R R+ E E + E + + ++ + D + E++ E
Sbjct: 446 KQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGI-LEKQPSPEEI 504
Query: 64 RQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERD 123
R+R+RE+E ERE E ++E++++RE++R+ DRER +++++E ++E ++ RE ++ +E++
Sbjct: 505 REREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKE 564
Query: 124 KQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKK 183
K+ ER++++E+E Q+ +E+E++ + E++RE E+ E E E E+++
Sbjct: 565 KELERQKEKEKELQKMKEQEKECELEKEREKLEEK---IEPREPNLEPMVEKQESENSCN 621
Query: 184 KEEK---RREDKKR 194
KEE+ R+D R
Sbjct: 622 KEEEPVFTRQDSNR 635
Score = 100 bits (249), Expect = 8e-22
Identities = 48/187 (25%), Positives = 115/187 (61%), Gaps = 4/187 (2%)
Query: 18 ERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQR----ERETE 73
E E +QR R+ R R R E +R+ + +++ ++ R ++ E++
Sbjct: 441 EDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPS 500
Query: 74 RETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRE 133
E R+RER+++RER+++ ++E++++R++ER+++ +R +E+ ++ +E++KQ E E++R+
Sbjct: 501 PEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERK 560
Query: 134 RERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKK 193
+E++++ ER++++++E ++ ++E++ E+E K E K E ++ E E++ E+
Sbjct: 561 QEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSC 620
Query: 194 RKWGEGI 200
K E +
Sbjct: 621 NKEEEPV 627
Score = 99.4 bits (246), Expect = 2e-21
Identities = 48/188 (25%), Positives = 114/188 (60%), Gaps = 9/188 (4%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTEREN-RHRQRDRHRERDRQTDREKERERQ 59
+ER R+R+ E +R E +R+ + + E+ +Q R+R+ ++E+ERE++
Sbjct: 459 VERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKE 518
Query: 60 KERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
E++++++RE+E E++ ERQ+E++++ E++++ RE +K+R +E+++E +R
Sbjct: 519 LEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQ-------- 570
Query: 120 RERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKER 179
+E++K+ ++ +++E+E + ++ERE+ ++ RE + E + E +++E R
Sbjct: 571 KEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTR 630
Query: 180 KEKKKEEK 187
++ + EK
Sbjct: 631 QDSNRSEK 638
Score = 98.2 bits (243), Expect = 4e-21
Identities = 50/170 (29%), Positives = 104/170 (61%), Gaps = 2/170 (1%)
Query: 16 ETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERE 75
E E + R+R++ + R R+R ER + R+ + +R ++ E +
Sbjct: 441 EDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPS 500
Query: 76 TERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERE 135
E RER+R++ER+R+ + E++++++RE++RE DR R++ ++ +E +K+ E++R+ E+E
Sbjct: 501 PEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKE--KELEKEQEKQREMEKE 558
Query: 136 RQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKE 185
R++++E+E +RQ+E+++E + +++ E E K+ K E K E +E E
Sbjct: 559 RKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLE 608
Score = 92.4 bits (228), Expect = 2e-19
Identities = 54/206 (26%), Positives = 125/206 (60%), Gaps = 19/206 (9%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
R+RER++E +R KE E+E++++RE+E R++ RER ++ ++E E+E++K+R
Sbjct: 505 REREREKEREREKELEKEQEQEREKE-----------REKDRERQQEKEKELEKEQEKQR 553
Query: 63 DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRER 122
+ +++R++E E+E ERQ+E++++ ++ ++ ++E + +++RE+ E RE N + E+
Sbjct: 554 EMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEK 613
Query: 123 DKQTERERDRERERQRQRERERQRQRERK---RETDRE---RQRWAEREERKKERKKERK 176
+++E ++E E R+ + ++E ET+ E + R A K+ +K
Sbjct: 614 -QESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKS-L 671
Query: 177 KERKEKKKEEKRREDKKRKWGEGISP 202
R ++++E+ +++ +++ +G+ P
Sbjct: 672 PPRFQRQQEQMKQQQWQQQQQQGVLP 697
Score = 86.3 bits (212), Expect = 2e-17
Identities = 45/185 (24%), Positives = 107/185 (57%), Gaps = 4/185 (2%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERE---NRHRQRDRHRERDRQTDREKERER 58
E++RER++E ++ +E ERE++R+++RE Q E+E + +++ R E++R+ ++EKE ER
Sbjct: 510 EKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELER 569
Query: 59 QKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKG 118
QKE++++ Q+ +E E+E E ++ER++ E+ + + +++ + E N+E
Sbjct: 570 QKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQ-ESENSCNKEEEPVF 628
Query: 119 GRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKE 178
R+ ++E+E + R + ++ R +R++E+ K+++ +
Sbjct: 629 TRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQ 688
Query: 179 RKEKK 183
+++++
Sbjct: 689 QQQQQ 693
Score = 52.0 bits (123), Expect = 3e-07
Identities = 34/160 (21%), Positives = 86/160 (53%), Gaps = 19/160 (11%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
+E+++E++RE ++ ++ E+E++ +R++E + E + + +E++++ + EKERE+ +
Sbjct: 545 LEKEQEKQREMEKERKQEKEKELERQKEKEKELQ-------KMKEQEKECELEKEREKLE 597
Query: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
E+ R+ E E +++ E +E + R+ D +R K T E + G
Sbjct: 598 EKIEPREPNLEPMVE-KQESENSCNKEEEPVFTRQ---DSNRSEKEATPVVHETEPESGS 653
Query: 121 ERD--------KQTERERDRERERQRQRERERQRQRERKR 152
+ KQ ++ +RQ+++ +++Q Q+++++
Sbjct: 654 QPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQ 693
Score = 43.1 bits (100), Expect = 2e-04
Identities = 35/140 (25%), Positives = 64/140 (45%), Gaps = 53/140 (37%)
Query: 109 DRNRERNRKGGRERDKQTERERDRERERQRQRE--------------------------- 141
DR R G +Q E + ++R+RQ+
Sbjct: 421 DRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAA 480
Query: 142 ------------------------RERQRQRERKRETDRERQRWAERE-ERKKERKKERK 176
RER+R++ER+RE + E+++ ERE ER+K+R+++++
Sbjct: 481 CAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQE 540
Query: 177 KERKEKKKEEKRRE-DKKRK 195
KE++ +K++EK+RE +K+RK
Sbjct: 541 KEKELEKEQEKQREMEKERK 560
Score = 37.0 bits (84), Expect = 0.011
Identities = 31/163 (19%), Positives = 64/163 (39%), Gaps = 9/163 (5%)
Query: 40 RDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDK- 98
R H + + Q+ + +++ Q +R E + R+R ++ D +R +
Sbjct: 883 RPHHTDANNQSACFEAPDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEP 942
Query: 99 --------DRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRER 150
R + K +R E+ +K G R + + + + R R R
Sbjct: 943 SAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRR 1002
Query: 151 KRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKK 193
+ DR +R ++ KE +++RKEK+ E+ + +K
Sbjct: 1003 EEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEK 1045
Score = 35.8 bits (81), Expect = 0.025
Identities = 42/201 (20%), Positives = 80/201 (39%), Gaps = 15/201 (7%)
Query: 3 RQRERKRETDRGKETE--RERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
RQRE + E +R RQR E T+ E D +D + + + ++
Sbjct: 1237 RQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESASD----KDSLSKGKLPKREER 1292
Query: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERN-RKGG 119
+++ + + + R R E+ D ++ K + T R R R+GG
Sbjct: 1293 PENKKPVKPHSSFKPDNHVRIDNRLLEKPYVRDDDKAKPGFLPKGEPTRRGRGGTFRRGG 1352
Query: 120 RERDKQTERERDRERERQRQRE---RERQRQRERKRETDRERQRW----AEREERKKERK 172
R+ + R R R + R+ + + E R +++ A++ K ERK
Sbjct: 1353 RDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPEDGEPPRRHEQFIPIAADKRPPKFERK 1412
Query: 173 KERKKERKEKKKEEK-RREDK 192
+ +ER +++ + R+DK
Sbjct: 1413 FDPARERPRRQRPTRPPRQDK 1433
Score = 33.9 bits (76), Expect = 0.097
Identities = 42/167 (25%), Positives = 66/167 (39%), Gaps = 33/167 (19%)
Query: 53 EKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRD---RERKRETD 109
EK+ E+ +D +R R R ++ R ++ RERD D R R R
Sbjct: 1135 EKQPEKVISKDLVIERPRPDSRPAVKKESTLPPRTYWKEA-RERDWFPDQGYRGRGRGEY 1193
Query: 110 RNRERNRKG--------GRERDKQTERERD-------------RERERQRQRER------ 142
+R R+ +G GR + + RD R+RE R
Sbjct: 1194 YSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKPRAEHIPSGPLRQREESETRSESSDFEV 1253
Query: 143 --ERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEK 187
+R+RQR + +TD E A ++ + K +++ER E KK K
Sbjct: 1254 VPKRRRQRGSETDTDSEIHESASDKDSLSKGKLPKREERPENKKPVK 1300
Score = 33.5 bits (75), Expect = 0.13
Identities = 30/136 (22%), Positives = 54/136 (39%), Gaps = 13/136 (9%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREK------ 54
+E Q RKR G ++ D QR + + R D +R ++ K
Sbjct: 915 VESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIR 974
Query: 55 --ERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNR 112
E + ++ + + R R + +RE R +R ++ RD + +RE
Sbjct: 975 SSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEERE----- 1029
Query: 113 ERNRKGGRERDKQTER 128
+R K G + +K TE+
Sbjct: 1030 QRKEKEGEKAEKVTEK 1045
Score = 32.3 bits (72), Expect = 0.28
Identities = 32/162 (19%), Positives = 64/162 (39%), Gaps = 12/162 (7%)
Query: 24 QRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQ 83
Q ER + E + ++ H Q E+ E + R +++ ER E+
Sbjct: 908 QEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKP 967
Query: 84 RQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERE 143
++ R ++ + + + +++ R G R + E DR R ++
Sbjct: 968 KKEGFIRSSEGPKPE--------KVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKP 1019
Query: 144 RQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKE 185
R + +RE +E+ E E+ +K +K K K +KK+
Sbjct: 1020 VLRDMKEEREQRKEK----EGEKAEKVTEKVVVKPEKTEKKD 1057
Score = 32.0 bits (71), Expect = 0.37
Identities = 33/157 (21%), Positives = 57/157 (36%), Gaps = 20/157 (12%)
Query: 47 DRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERK-----RQTDRERDKDRD 101
D++T + ER + Q R+R + ++ QR + T R D
Sbjct: 900 DQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEP 959
Query: 102 RERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERK---------- 151
ER E + R + ++ + + R R R+ +R
Sbjct: 960 IERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKP 1019
Query: 152 --RETDRERQRWAEREERKKERKKER---KKERKEKK 183
R+ ER++ E+E K E+ E+ K E+ EKK
Sbjct: 1020 VLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKK 1056
Score = 27.7 bits (60), Expect = 6.9
Identities = 14/63 (22%), Positives = 32/63 (50%)
Query: 123 DKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEK 182
D Q+ D E +++++R + ER+++ ++ Q W ++ +K R + K +
Sbjct: 1671 DPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEKGRSQTSKLPPRFA 1730
Query: 183 KKE 185
KK+
Sbjct: 1731 KKQ 1733
Score = 27.3 bits (59), Expect = 9.0
Identities = 11/41 (26%), Positives = 27/41 (65%)
Query: 158 RQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGE 198
+Q+ A+ +E K+R++++ + ++ KRRE+++R+ E
Sbjct: 435 KQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEE 475
>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
sapiens]
Length = 375
Score = 107 bits (266), Expect = 9e-24
Identities = 63/197 (31%), Positives = 107/197 (54%), Gaps = 14/197 (7%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQ-RDRHRERDRQTDREKERERQKE 61
R+ E K ++ + ++E D++ + ER N DRH+ ++R++ R + R +
Sbjct: 12 RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
R+R R R R ER+ R R R+R++ R R +R++ + R RERKR R+R R+R R
Sbjct: 72 RER-RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRI-RSRSRSRSRHRH 129
Query: 122 RDKQTERERDRERERQRQRERERQRQRE----------RKRETDRERQR-WAEREERKKE 170
R + R R R R+R+++ E+ R+ R R R T + Q A R ER K+
Sbjct: 130 RTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKK 189
Query: 171 RKKERKKERKEKKKEEK 187
+++R+KE EK+K+++
Sbjct: 190 LQEQREKEMVEKQKQQE 206
Score = 89.7 bits (221), Expect = 1e-18
Identities = 51/152 (33%), Positives = 78/152 (51%), Gaps = 8/152 (5%)
Query: 38 RQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERD 97
+Q RH +D+ + + K E +++ + RE +E +R +++ERK R
Sbjct: 9 KQGRRHESKDKSSKKHKSEEHN-DKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 67
Query: 98 KDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRE 157
+ R RER R R+RER + R R+++ R R RER++ R R RER+R R R R R
Sbjct: 68 RSRSRER-RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR-RIRSRSRSRS 125
Query: 158 RQRWAEREERKKERKKERKKERKEKKKEEKRR 189
R R R + R + R + R KK+ EK R
Sbjct: 126 RHR-----HRTRSRSRTRSRSRDRKKRIEKPR 152
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
Length = 1341
Score = 104 bits (260), Expect = 4e-23
Identities = 64/200 (32%), Positives = 113/200 (56%), Gaps = 18/200 (9%)
Query: 13 RGKETERERDRQRERENQTERENRHRQRDR-HRERDRQTDREKERERQKERDRQR-QRER 70
R ++ E+ER RE+ + ERE R+R R RE DR RE R R + RDR+R +R +
Sbjct: 1132 RAEQREQER-AVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAK 1190
Query: 71 ETERETERQRERQRQRERKRQTDRER--------------DKDRDRERKRETDRNRERN- 115
E+++E++ + Q + K D R D ++ +R +ER
Sbjct: 1191 SKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREK 1250
Query: 116 RKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKER 175
R+ +E ++Q ERE++ ERER RQ ERE++R+ R+R+ +RER+R +R +R ++R+++R
Sbjct: 1251 RRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDR 1310
Query: 176 KKERKEKKKEEKRREDKKRK 195
++ R+ +++ KR + +
Sbjct: 1311 ERGRERDRRDTKRHSRSRSR 1330
Score = 103 bits (256), Expect = 1e-22
Identities = 65/214 (30%), Positives = 111/214 (51%), Gaps = 38/214 (17%)
Query: 2 ERQRERKRETDRG-KETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
+ R +RE +R +E ER+R+ ER +T R R RD+ RE R R ++R R+K
Sbjct: 1129 QHPRAEQREQERAVREQWAEREREMERRERT-RSEREWDRDKVREGPRSRSRSRDR-RRK 1186
Query: 61 ERDRQRQRERETERETER-------------------------------QRERQRQRERK 89
ER + ++++ E + + + Q+E +R K
Sbjct: 1187 ERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAK 1246
Query: 90 RQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRER-ERQRQR 148
+ R ++++ + +++RE + RERNR+ RE+ ++ RERDRERER+R+R+R +R R R
Sbjct: 1247 EREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDR 1306
Query: 149 ERKRETDRERQRWAEREERKKERKKERKKERKEK 182
ER RE RER R R+ ++ R + R +++
Sbjct: 1307 ERDRERGRERDR---RDTKRHSRSRSRSTPVRDR 1337
Score = 99.8 bits (247), Expect = 1e-21
Identities = 64/204 (31%), Positives = 107/204 (52%), Gaps = 36/204 (17%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
E+ ER+RE +R + T ER+ R++ + R +R R RDR R+ +R K +E++ E
Sbjct: 1144 EQWAEREREMERRERTRSEREWDRDKVREGPR-SRSRSRDRRRK-----ERAKSKEKKSE 1197
Query: 62 RDRQRQRE----------RET-----------------ERETERQRERQRQRERKRQTDR 94
+ + Q E R+T ++E ER + + +R+++ +
Sbjct: 1198 KKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEE 1257
Query: 95 ERDKDRDRERKRETDR--NRERNRKGGRERDKQTERERDRER-ERQRQRERERQRQRERK 151
E K+R++E +RE +R RE+ R+ RERD++ ERER+R+R +R R RER+R+R RER
Sbjct: 1258 EEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRERGRERD 1317
Query: 152 RETDRERQRWAEREERKKERKKER 175
R + R R ++R R
Sbjct: 1318 RRDTKRHSRSRSRSTPVRDRGGRR 1341
Score = 73.6 bits (179), Expect = 1e-13
Identities = 49/170 (28%), Positives = 91/170 (53%), Gaps = 34/170 (20%)
Query: 59 QKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKG 118
Q R QR++ER RE +RER+ +R + +++RE D+D+ RE R R+R+R RK
Sbjct: 1129 QHPRAEQREQERAV-REQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKE 1187
Query: 119 -GRERDKQTERERDRERER-----------------------------QRQRER-ERQRQ 147
+ ++K++E++ + E Q++ ER ER ++
Sbjct: 1188 RAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKE 1247
Query: 148 RERKR-ETDRERQRWAERE-ERKKERKKERKKERKEKKKEEKRREDKKRK 195
RE++R E + E Q+ E+E ER++ R+ ER+K R+ ++ ++ RE ++ +
Sbjct: 1248 REKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERER 1297
Score = 55.1 bits (131), Expect = 4e-08
Identities = 44/192 (22%), Positives = 84/192 (43%), Gaps = 21/192 (10%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
ER+ R R+ K +E + + E + +T N + DR+ + T+ E+E E ++E
Sbjct: 225 ERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLK----TEEEEEEEEEEE 280
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTD---RERDKDRDRERKRETDRNRERNRKG 118
D E E + E ++ RE +E K + + R + ++ ER + + +E +G
Sbjct: 281 ED---DEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERG 337
Query: 119 GRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKE 178
GR Q E + +Q+++E + E + ERE + + KE+ K
Sbjct: 338 GRFTRSQEEARKSHLARQQQEKEMKTTSPLEEE-----------EREIKSSQGLKEKSKS 386
Query: 179 RKEKKKEEKRRE 190
+ E R++
Sbjct: 387 PSPPRLTEDRKK 398
Score = 49.7 bits (117), Expect = 2e-06
Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 12/68 (17%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
+ER++ R+ +R +E ERER+R R RDR RERDR+ RE++R K
Sbjct: 1275 LEREKRREHSRERDRERERERERDR------------GDRDRDRERDRERGRERDRRDTK 1322
Query: 61 ERDRQRQR 68
R R R
Sbjct: 1323 RHSRSRSR 1330
Score = 48.9 bits (115), Expect = 3e-06
Identities = 45/198 (22%), Positives = 90/198 (45%), Gaps = 13/198 (6%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHR--ERDRQTDREKERER 58
+E R R++ E + + D ++ R+ + R +R RQ + E + + E+++E
Sbjct: 196 LELSRHSPRKSSSISEEKGDSDDEKPRKGE-RRSSRVRQARAAKLSEGSQPAEEEEDQET 254
Query: 59 QKERDRQR-QRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRK 117
R R R +TE E E + E + + D E + D + ++ RE +E +
Sbjct: 255 PSRNLRVRADRNLKTEEEEEEEEEEE-------EDDEEEEGDDEGQKSREAPILKEFKEE 307
Query: 118 GGR-ERDKQTERERDRERERQRQRE-RERQRQRERKRETDRERQRWAEREERKKERKKER 175
G R K E +R + R +++E ER + R +E R+ +++E++ +
Sbjct: 308 GEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPL 367
Query: 176 KKERKEKKKEEKRREDKK 193
++E +E K + +E K
Sbjct: 368 EEEEREIKSSQGLKEKSK 385
Score = 46.6 bits (109), Expect = 1e-05
Identities = 41/194 (21%), Positives = 82/194 (42%), Gaps = 11/194 (5%)
Query: 6 ERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQ----KE 61
E K ++D K + ER R R+ + + + Q E D++T R R K
Sbjct: 211 EEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQ-PAEEEEDQETPSRNLRVRADRNLKT 269
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
+ + + E E E + E + + + Q+ R+ +E +E E R + R
Sbjct: 270 EEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKE-----FKEEGEEIPRVKPEEMMDERP 324
Query: 122 RDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKE 181
+ + E+E R + + E ++ +++ ++E + + EE ++E K + + K
Sbjct: 325 KTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKS 384
Query: 182 KKKEEKR-REDKKR 194
K R ED+K+
Sbjct: 385 KSPSPPRLTEDRKK 398
Score = 45.8 bits (107), Expect = 2e-05
Identities = 39/191 (20%), Positives = 85/191 (44%), Gaps = 13/191 (6%)
Query: 18 ERERDRQRERENQTERENRHRQRD-RHRERDRQTDREKERERQKERDRQRQRERETERET 76
E E R R++ + E + D + R+ +R++ R ++ K + + E E ++ET
Sbjct: 195 ELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQET 254
Query: 77 ERQRERQRQ----RERKRQTDRERDKDRDRERKRETDRNRERN-------RKGGRERDKQ 125
+ R R + + + + E +++ D E + + + + R ++ G E +
Sbjct: 255 PSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRV 314
Query: 126 TERERDRERERQRQRERE-RQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKK 184
E ER + R +E+E +R R + R+ R++++KE K E +E++
Sbjct: 315 KPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREI 374
Query: 185 EEKRREDKKRK 195
+ + +K K
Sbjct: 375 KSSQGLKEKSK 385
Score = 38.1 bits (87), Expect = 0.005
Identities = 35/153 (22%), Positives = 63/153 (41%), Gaps = 12/153 (7%)
Query: 53 EKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNR 112
EK++E ++R + RE E + E + + D ER
Sbjct: 142 EKQQELLRQRLEREAREAAELEEASAESEDEMIHPEGVASLLPPDFQSSLERPE-----L 196
Query: 113 ERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKE-- 170
E +R R+ +E + D + E+ R+ ER R R+ + E + AE EE ++
Sbjct: 197 ELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPS 256
Query: 171 -----RKKERKKERKEKKKEEKRREDKKRKWGE 198
R K +E+++EE+ ED + + G+
Sbjct: 257 RNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGD 289
Score = 31.6 bits (70), Expect = 0.48
Identities = 18/84 (21%), Positives = 26/84 (30%)
Query: 89 KRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQR 148
K+ D + R+R + G R ++RD + R R R +
Sbjct: 571 KQSADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQARTHANPRGRPKMG 630
Query: 149 ERKRETDRERQRWAEREERKKERK 172
R R R R R RK
Sbjct: 631 SRSTSESRSRSRSRSRSASSNSRK 654
Score = 31.6 bits (70), Expect = 0.48
Identities = 19/76 (25%), Positives = 26/76 (34%)
Query: 59 QKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKG 118
++ D R + + R R R R R K RD + R R R + G
Sbjct: 571 KQSADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQARTHANPRGRPKMG 630
Query: 119 GRERDKQTERERDRER 134
R + R R R R
Sbjct: 631 SRSTSESRSRSRSRSR 646
Score = 30.8 bits (68), Expect = 0.82
Identities = 22/108 (20%), Positives = 36/108 (33%), Gaps = 3/108 (2%)
Query: 23 RQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRE- 81
+Q E + R H HR + + D R R R R + R
Sbjct: 548 KQPSLEQKEGRRASHTLLPSHRLK-QSADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSP 606
Query: 82 -RQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTER 128
R +QR+ + + R + R T +R R+R R + +
Sbjct: 607 LRSKQRDVAQARTHANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRK 654
>gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo
sapiens]
Length = 437
Score = 104 bits (260), Expect = 4e-23
Identities = 65/170 (38%), Positives = 93/170 (54%), Gaps = 37/170 (21%)
Query: 37 HRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRER 96
HR RDR RER+R RE+ RER KER+R+R R R+ R+R R R +E +R++ RER
Sbjct: 230 HRDRDRDRERER---RERSRERDKERERRRSRSRD-----RRRRSRSRDKEERRRS-RER 280
Query: 97 DKDRDRERKRETDRNRERNRK----------GGRERDKQTER------------------ 128
KD+DR+RKR + R+RER R+ GG + + +E
Sbjct: 281 SKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGP 340
Query: 129 ERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKE 178
+ E+ R R RER R + ER+R DR+R R +RE ++ ER ER ++
Sbjct: 341 DGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRD 390
Score = 99.4 bits (246), Expect = 2e-21
Identities = 61/183 (33%), Positives = 88/183 (48%), Gaps = 33/183 (18%)
Query: 20 ERDRQRERENQTERENRHRQRDRHRER---DRQTDREKERERQKERDRQRQRERETERET 76
+ R ER + +R R RDR RER R+ D+E+ER R + RDR+R+ + E
Sbjct: 215 DTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEER 274
Query: 77 ERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTE--------- 127
R RER + ++R DR+R R RER R +E R GG + + +E
Sbjct: 275 RRSRERSKDKDR----DRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDG 330
Query: 128 -----------------RERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKE 170
R+RDRER R + ERER+R R+R R+ DRE +R ER ++
Sbjct: 331 PPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRD 390
Query: 171 RKK 173
+
Sbjct: 391 EAR 393
Score = 93.6 bits (231), Expect = 1e-19
Identities = 61/166 (36%), Positives = 85/166 (51%), Gaps = 15/166 (9%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
R R+R RE +R +E RERD++RER R+ R R R R +E +R + RER K++
Sbjct: 231 RDRDRDRERER-RERSRERDKERERRRSRSRDRRRRSRSRDKE-----ERRRSRERSKDK 284
Query: 63 DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKG---- 118
DR R+R RE R RER+R+ E + + + + E G
Sbjct: 285 DRDRKRRSSRSRERAR-RERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGP 343
Query: 119 ---GRERDKQTERERDRERERQRQRERERQRQRERKR-ETDRERQR 160
GR+RD++ R ERER+R R+R+R R RE KR E ER R
Sbjct: 344 EEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGR 389
Score = 86.7 bits (213), Expect = 1e-17
Identities = 58/184 (31%), Positives = 89/184 (48%), Gaps = 45/184 (24%)
Query: 2 ERQRERK-RETDRGKETERERDRQRERENQTE-RENRHRQRDRHRERDRQTDREKERERQ 59
+R+RER+ R +R KE ER R R R+R ++ R+ R+R R R +D+ DR++ R
Sbjct: 236 DRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRS 295
Query: 60 KERDRQRQRERETE---------------------------------------RETERQR 80
+ER R R+RER+ E R+ +R+R
Sbjct: 296 RERAR-RERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRER 354
Query: 81 ERQRQRERKRQTDRERDKDRDRERK---RETDRNRERNRKGGRERDKQTERERDRERERQ 137
R + ER+R+ DR+RD+DRDRE K R ++R R+ R GG +D E + R+
Sbjct: 355 RRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEARGGGGGQDNGLEGLGNDSRDMY 414
Query: 138 RQRE 141
+ E
Sbjct: 415 MESE 418
Score = 79.0 bits (193), Expect = 3e-15
Identities = 51/166 (30%), Positives = 79/166 (47%), Gaps = 46/166 (27%)
Query: 78 RQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQ 137
R R+R R+RER R+ RERDK+R+R R R DR R + ER + ER +D++R+R+
Sbjct: 231 RDRDRDRERER-RERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRK 289
Query: 138 RQRERERQ---RQRERK-----------------------------------------RE 153
R+ R R+ R+RERK R+
Sbjct: 290 RRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRD 349
Query: 154 TDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGEG 199
DRER+R + R ER++ R ++R ++R + K +R ++ R G
Sbjct: 350 RDRERRR-SHRSERERRRDRDRDRDRDREHKRGERGSERGRDEARG 394
Score = 47.4 bits (111), Expect = 8e-06
Identities = 60/232 (25%), Positives = 93/232 (40%), Gaps = 53/232 (22%)
Query: 9 RETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKE----RERQKERDR 64
R R + ER+R + ER Q E E + D H + + Q D K R +
Sbjct: 59 RAETREERMERKRREKIERRQQ-EVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTES 117
Query: 65 QRQRERETERETER--------------------QRERQRQRERKRQTDRERDKDR---D 101
+ +RE E +R + ER K ++ D R D
Sbjct: 118 KLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVD 177
Query: 102 RERKRETDRNRERN--------RKGGRERDKQTERERDRERERQR-------QRERERQR 146
ER R R R R+GG + + + D R +R R+R+R R
Sbjct: 178 VERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDR 237
Query: 147 QRERKRETDRERQRWAERE---ERKKERKKERKKERKEKKKEEKRREDKKRK 195
+RER RER R ER+ ER++ R ++R++ + + KEE+RR ++ K
Sbjct: 238 ERER-----RERSR--ERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSK 282
>gi|213385278 TNF receptor-associated factor 3 interacting protein 1
isoform 2 [Homo sapiens]
Length = 625
Score = 103 bits (257), Expect = 1e-22
Identities = 57/188 (30%), Positives = 105/188 (55%), Gaps = 7/188 (3%)
Query: 5 RERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDR 64
R ++ + +E E + E E + R RDR ++ + + DR K RE+ K++++
Sbjct: 145 RSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDR-KPREKDKDKEK 203
Query: 65 QRQRERETERETERQRERQRQR-ERKRQTDR-ERDKDRDRERKRETDRNRERNRKGGRER 122
++ RE ER+R + R R + +RQ DR R++DRD ERK+ET+R E GG+E+
Sbjct: 204 AKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSE----GGKEK 259
Query: 123 DKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEK 182
++ +R+R+R+R++ + R+R R + E + DRE+ R ++ E+K E K+ +
Sbjct: 260 ERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDG 319
Query: 183 KKEEKRRE 190
++ + E
Sbjct: 320 TFKDSKAE 327
Score = 94.0 bits (232), Expect = 8e-20
Identities = 57/187 (30%), Positives = 98/187 (52%), Gaps = 14/187 (7%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
E R K DRG +ER R+R+ + E + + R++ +++++ + R R+ E
Sbjct: 157 EESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGE 216
Query: 62 RDRQRQRER-ETERETER-QRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
R+R + R R + ER+ +R RER R ERK++T+R+ + +++ER R DR+RER+R G
Sbjct: 217 RERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLR--DRDRERDRDKG 274
Query: 120 RERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKER 179
+DR+R R + E RE+ RE D+ ++ A E K+ K+
Sbjct: 275 ----------KDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDS 324
Query: 180 KEKKKEE 186
K + + E
Sbjct: 325 KAETETE 331
Score = 85.1 bits (209), Expect = 4e-17
Identities = 54/177 (30%), Positives = 91/177 (51%), Gaps = 15/177 (8%)
Query: 2 ERQRERK-RETDRGKETERERDRQRERENQTERENRHRQRDRHRERDR-QTDREKERERQ 59
E + +RK RE D+ KE +E R RE + ER + D R++DR +R+++ ER+
Sbjct: 187 ELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERK 246
Query: 60 KERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
K ETER++E +E++R R+R R+ DR++ KDRDR R + + + + +R+
Sbjct: 247 K----------ETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKN 296
Query: 120 RERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERK 176
RE DK E+ + ++ ++ K ET+ E A + K K+ K
Sbjct: 297 REHDKP---EKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSK 350
Score = 83.6 bits (205), Expect = 1e-16
Identities = 51/188 (27%), Positives = 102/188 (54%), Gaps = 15/188 (7%)
Query: 13 RGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERET 72
+G+ + R ++ + +N E E+R H+ + + D E +ER RDR+++ E +
Sbjct: 137 KGRASLTSRSQELDNKNVREEESRV-----HKNTEDRGDAEI-KERSTSRDRKQKEELKE 190
Query: 73 ERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDR 132
+R+ R++++ +++ ++ +R R+ +R+R + R N + +G RERD RD
Sbjct: 191 DRKP-REKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERD------RDS 243
Query: 133 ERERQRQRERERQRQRERKRETDRERQR--WAEREERKKERKKERKKERKEKKKEEKRRE 190
ER+++ +R+ E +++ER R+ DRER R +R+ R+ + + +EK +E + E
Sbjct: 244 ERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPE 303
Query: 191 DKKRKWGE 198
K GE
Sbjct: 304 KKSASSGE 311
Score = 79.7 bits (195), Expect = 2e-15
Identities = 52/176 (29%), Positives = 93/176 (52%), Gaps = 18/176 (10%)
Query: 32 ERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQ 91
E + R R +E D + RE+E K + + E + ER T R R +Q+E ++
Sbjct: 135 EVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIK-ERSTSRDR---KQKEELKE 190
Query: 92 TDRERDKDRDRERKRETDRNRERNRKGGRERDK------------QTERERDRERERQRQ 139
+ R+KD+D+E+ +E NR +R+G RER K + RERDR+ ER+++
Sbjct: 191 DRKPREKDKDKEKAKENGGNR--HREGERERAKARARPDNERQKDRGNRERDRDSERKKE 248
Query: 140 RERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRK 195
ER+ + +E++R DR+R+R ++ + + R+ + + + +E+ R DK K
Sbjct: 249 TERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEK 304
Score = 68.9 bits (167), Expect = 3e-12
Identities = 47/147 (31%), Positives = 77/147 (52%), Gaps = 16/147 (10%)
Query: 55 ERERQKERDRQRQRERETERETERQRERQRQRERKRQTD---RERDKDRDRERKRETDRN 111
E+ K R R +E + + R+ E + + + + D +ER RDR++K E +
Sbjct: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKED 191
Query: 112 RERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKER 171
R+ RE+DK E+ ++ R R+ ERER + R R D ERQ+ +R R+++R
Sbjct: 192 RKP-----REKDKDKEKAKENGGNRHREGERERAKARAR---PDNERQK--DRGNRERDR 241
Query: 172 KKERKKERKEKK---KEEKRREDKKRK 195
ERKKE + K KE++R D+ R+
Sbjct: 242 DSERKKETERKSEGGKEKERLRDRDRE 268
Score = 52.4 bits (124), Expect = 3e-07
Identities = 28/126 (22%), Positives = 63/126 (50%), Gaps = 8/126 (6%)
Query: 81 ERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE-RDKQTERERDRERE---- 135
E+ + R T R ++ D R+ E+ ++ +G E +++ T R+R ++ E
Sbjct: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKED 191
Query: 136 ---RQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDK 192
R++ +++E+ ++ R + ER+R R ER+K+R +++ E K+ ++
Sbjct: 192 RKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETER 251
Query: 193 KRKWGE 198
K + G+
Sbjct: 252 KSEGGK 257
Score = 42.0 bits (97), Expect = 4e-04
Identities = 24/104 (23%), Positives = 52/104 (50%), Gaps = 1/104 (0%)
Query: 97 DKDRDRERKRETDRNRERNRKGGRERDKQTERE-RDRERERQRQRERERQRQRERKRETD 155
+K + R T R++E + K RE + + + DR ++R R R+++ + + D
Sbjct: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKED 191
Query: 156 RERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGEG 199
R+ + + +E+ KE R +E + ++ + + R D +R+ G
Sbjct: 192 RKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRG 235
>gi|20070262 TNF receptor-associated factor 3 interacting protein 1
isoform 1 [Homo sapiens]
Length = 691
Score = 103 bits (257), Expect = 1e-22
Identities = 57/188 (30%), Positives = 105/188 (55%), Gaps = 7/188 (3%)
Query: 5 RERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDR 64
R ++ + +E E + E E + R RDR ++ + + DR K RE+ K++++
Sbjct: 145 RSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDR-KPREKDKDKEK 203
Query: 65 QRQRERETERETERQRERQRQR-ERKRQTDR-ERDKDRDRERKRETDRNRERNRKGGRER 122
++ RE ER+R + R R + +RQ DR R++DRD ERK+ET+R E GG+E+
Sbjct: 204 AKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSE----GGKEK 259
Query: 123 DKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEK 182
++ +R+R+R+R++ + R+R R + E + DRE+ R ++ E+K E K+ +
Sbjct: 260 ERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDG 319
Query: 183 KKEEKRRE 190
++ + E
Sbjct: 320 TFKDSKAE 327
Score = 95.5 bits (236), Expect = 3e-20
Identities = 55/205 (26%), Positives = 105/205 (51%), Gaps = 17/205 (8%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
E R K DRG +ER R+R+ + E + + R++ +++++ + R R+ E
Sbjct: 157 EESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGE 216
Query: 62 RDRQRQRER-ETERETER-QRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
R+R + R R + ER+ +R RER R ERK++T+R+ + +++ER R DR+RER+R G
Sbjct: 217 RERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLR--DRDRERDRDKG 274
Query: 120 RERDKQTERERDRERERQRQRERERQRQRERKRET-------------DRERQRWAEREE 166
++RD++ + + + R++ RE + ++ + D + + E
Sbjct: 275 KDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEIST 334
Query: 167 RKKERKKERKKERKEKKKEEKRRED 191
R + + +R+ K E R+ED
Sbjct: 335 RASKSLTTKTSKRRSKNSVEGRKED 359
Score = 90.1 bits (222), Expect = 1e-18
Identities = 51/186 (27%), Positives = 106/186 (56%), Gaps = 12/186 (6%)
Query: 13 RGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERET 72
+G+ + R ++ + +N E E+R H+ + + D E +ER RDR+++ E +
Sbjct: 137 KGRASLTSRSQELDNKNVREEESRV-----HKNTEDRGDAEI-KERSTSRDRKQKEELKE 190
Query: 73 ERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDR 132
+R+ R++++ +++ ++ +R R+ +R+R + R N + +G RERD+ +ER+++
Sbjct: 191 DRKP-REKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKET 249
Query: 133 ERE----RQRQRERERQRQRERKRETDRERQRWAEREER-KKERKKERKKERKEKKKEEK 187
ER+ ++++R R+R R+R+R + DR+R+R E +R+K R+ ++ EKK
Sbjct: 250 ERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASS 309
Query: 188 RREDKK 193
KK
Sbjct: 310 GEMSKK 315
Score = 79.7 bits (195), Expect = 2e-15
Identities = 52/176 (29%), Positives = 93/176 (52%), Gaps = 18/176 (10%)
Query: 32 ERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQ 91
E + R R +E D + RE+E K + + E + ER T R R +Q+E ++
Sbjct: 135 EVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIK-ERSTSRDR---KQKEELKE 190
Query: 92 TDRERDKDRDRERKRETDRNRERNRKGGRERDK------------QTERERDRERERQRQ 139
+ R+KD+D+E+ +E NR +R+G RER K + RERDR+ ER+++
Sbjct: 191 DRKPREKDKDKEKAKENGGNR--HREGERERAKARARPDNERQKDRGNRERDRDSERKKE 248
Query: 140 RERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRK 195
ER+ + +E++R DR+R+R ++ + + R+ + + + +E+ R DK K
Sbjct: 249 TERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEK 304
Score = 73.9 bits (180), Expect = 8e-14
Identities = 49/161 (30%), Positives = 89/161 (55%), Gaps = 12/161 (7%)
Query: 45 ERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRER---DKDRD 101
E+ R R +E D + RE E+ R + +R ++R T R+R ++ ++
Sbjct: 132 EKGEVKGRASLTSRSQELDNKNVREEES-RVHKNTEDRGDAEIKERSTSRDRKQKEELKE 190
Query: 102 RERKRETDRNRERNRKGGRERDKQTERERDRER-----ERQRQR-ERERQRQRERKRETD 155
+ RE D+++E+ ++ G R ++ ERER + R ERQ+ R RER R ERK+ET+
Sbjct: 191 DRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETE 250
Query: 156 RERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKW 196
R+ + E+ ER ++R +ER ++ K K ++ +R ++ + W
Sbjct: 251 RKSEGGKEK-ERLRDRDRERDRD-KGKDRDRRRVKNGEHSW 289
Score = 58.2 bits (139), Expect = 5e-09
Identities = 36/132 (27%), Positives = 68/132 (51%), Gaps = 10/132 (7%)
Query: 2 ERQRERKRETDRGKETER--ERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQ 59
ER++E +R+++ GKE ER +RDR+R+R+ +R+ R+R ++ E DREK RE
Sbjct: 244 ERKKETERKSEGGKEKERLRDRDRERDRDKGKDRD---RRRVKNGEHSWDLDREKNREHD 300
Query: 60 KERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
K +++ + E ++ ++ K +T+ E + +T + R +N G
Sbjct: 301 KP-----EKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEG 355
Query: 120 RERDKQTERERD 131
R+ D + + D
Sbjct: 356 RKEDNISAKSLD 367
Score = 52.4 bits (124), Expect = 3e-07
Identities = 28/126 (22%), Positives = 63/126 (50%), Gaps = 8/126 (6%)
Query: 81 ERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE-RDKQTERERDRERE---- 135
E+ + R T R ++ D R+ E+ ++ +G E +++ T R+R ++ E
Sbjct: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKED 191
Query: 136 ---RQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDK 192
R++ +++E+ ++ R + ER+R R ER+K+R +++ E K+ ++
Sbjct: 192 RKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETER 251
Query: 193 KRKWGE 198
K + G+
Sbjct: 252 KSEGGK 257
Score = 42.0 bits (97), Expect = 4e-04
Identities = 24/104 (23%), Positives = 52/104 (50%), Gaps = 1/104 (0%)
Query: 97 DKDRDRERKRETDRNRERNRKGGRERDKQTERE-RDRERERQRQRERERQRQRERKRETD 155
+K + R T R++E + K RE + + + DR ++R R R+++ + + D
Sbjct: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKED 191
Query: 156 RERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGEG 199
R+ + + +E+ KE R +E + ++ + + R D +R+ G
Sbjct: 192 RKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRG 235
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 102 bits (253), Expect = 3e-22
Identities = 66/195 (33%), Positives = 102/195 (52%), Gaps = 10/195 (5%)
Query: 2 ERQRERKRETDRGKETERERDRQ---RERENQTERENRHRQRDRHRERDRQTDREKERER 58
E + RKR RG+ R R R + + +R +R R RDR RER R D+ + R R
Sbjct: 4 ESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSR 63
Query: 59 QKER-DRQRQRERETERETERQRERQRQRERKRQTD-RERDKDRDRERKRETDRNRERNR 116
++R R R RER+ RE R R R R+R R R R R + K+ +R+R + +
Sbjct: 64 DRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEK 123
Query: 117 KGGRERDKQTERER-DRERERQRQRERERQRQRERKRETDRER-QRWAEREERKK--ERK 172
G E K+ ++++ D+E E+++ Q + E + +ER ++W E E+RKK E
Sbjct: 124 TDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWRE-EQRKKAMENI 182
Query: 173 KERKKERKEKKKEEK 187
E KKE +E K+ +K
Sbjct: 183 GELKKEIEEMKQGKK 197
Score = 96.3 bits (238), Expect = 2e-20
Identities = 58/185 (31%), Positives = 93/185 (50%), Gaps = 17/185 (9%)
Query: 14 GKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETE 73
G+E+ R R R R R R R + + + R + RDR R+RER
Sbjct: 2 GRESRHYRKRSASR-------GRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRS 54
Query: 74 RETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR--------ERDKQ 125
R+ R R R R+R R R RERD+ R+R R R DR R R+R GR + K+
Sbjct: 55 RDKRRSRSRDRKRLR-RSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKK 113
Query: 126 TERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKE 185
TE R R +E+ E +++++++ + D + + ++ K E + ++KER EK +E
Sbjct: 114 TE-NRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWRE 172
Query: 186 EKRRE 190
E+R++
Sbjct: 173 EQRKK 177
Score = 90.9 bits (224), Expect = 7e-19
Identities = 49/144 (34%), Positives = 77/144 (53%), Gaps = 8/144 (5%)
Query: 60 KERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
+E R+R R R R R +R ++ D R + RDR+R+RE R+R++ R
Sbjct: 3 RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRS 62
Query: 120 RERDK-QTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKE 178
R+R + + R R+R+R R+R+R R R R+R R R R + + + KK + R KE
Sbjct: 63 RDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKE 122
Query: 179 R-------KEKKKEEKRREDKKRK 195
+ KEKKK++ +ED+K K
Sbjct: 123 KTDGGESSKEKKKDKDDKEDEKEK 146
Score = 90.5 bits (223), Expect = 9e-19
Identities = 56/182 (30%), Positives = 95/182 (52%), Gaps = 16/182 (8%)
Query: 33 RENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQT 92
RE+RH R R R R R + R +R ++ R R+ +R+RER R R+++R
Sbjct: 3 RESRH-YRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSR 61
Query: 93 DRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRE-------RERQRQRERERQ 145
R+R + R R R RE DR+RER R R+R + R R R + ++ R R
Sbjct: 62 SRDRKRLR-RSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRS 120
Query: 146 RQRERKRETDRERQRWAEREERKKER-------KKERKKERKEKKKEEKRREDKKRKWGE 198
+++ E+ +E+++ + +E +KE+ K ++ RK K++ EK RE++++K E
Sbjct: 121 KEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAME 180
Query: 199 GI 200
I
Sbjct: 181 NI 182
Score = 87.8 bits (216), Expect = 6e-18
Identities = 54/192 (28%), Positives = 97/192 (50%), Gaps = 14/192 (7%)
Query: 4 QRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERD 63
+R R R+ DR +E R RD++R R R+ + +R R RERDR +R + R R + R
Sbjct: 38 RRSRSRDRDRRRERSRSRDKRRSRS----RDRKRLRRSRSRERDRSRERRRSRSRDRRRS 93
Query: 64 RQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERD 123
R R R R + R + + ++ R R ++ + +E+K++ D + K D
Sbjct: 94 RSRSRGRRS-RSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFD 152
Query: 124 KQTERERDRERERQRQRERERQRQR------ERKRETDRERQ--RWA-EREERKKERKKE 174
+ E R+R+ + ++ RE QR++ E K+E + +Q +W+ E ++ ++ E
Sbjct: 153 QNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAE 212
Query: 175 RKKERKEKKKEE 186
+KE E + EE
Sbjct: 213 AEKEGNEMEGEE 224
Score = 57.4 bits (137), Expect = 8e-09
Identities = 41/197 (20%), Positives = 86/197 (43%), Gaps = 17/197 (8%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
+ R R R+R+ R + R RDR+R R R +R ++ R KE+
Sbjct: 68 LRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGG 127
Query: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
E ++++++++ ++E E++++ D+ + ++ R+RK ++ RE RK
Sbjct: 128 ESSKEKKKDKD-DKEDEKEKD-------AGNFDQNKLEEEMRKRKERVEKWREEQRKKAM 179
Query: 121 ERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRW---------AEREERKKER 171
E + ++E + ++ ++ + + E ++E A EE K+E
Sbjct: 180 ENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELDPLDAYMEEVKEEV 239
Query: 172 KKERKKERKEKKKEEKR 188
KK + K EK+
Sbjct: 240 KKFNMRSVKGGGGNEKK 256
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 100 bits (249), Expect = 8e-22
Identities = 50/194 (25%), Positives = 110/194 (56%), Gaps = 1/194 (0%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
RQ E+ RE + K E+E R+ E E+E R+ ++ E+++ + EK +E++ +
Sbjct: 514 RQEEKIREQEE-KIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKM 572
Query: 63 DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRER 122
RQ ++ RE E + RQ E+ R++E KRQ E+ ++ + + + ++ +E+ K +
Sbjct: 573 WRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQE 632
Query: 123 DKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEK 182
+K E+E + + ++ E+E + + ++ ++E W + E+ +++ KK R++E K +
Sbjct: 633 EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIR 692
Query: 183 KKEEKRREDKKRKW 196
++EE +E +++ W
Sbjct: 693 EQEEMMQEQEEKMW 706
Score = 96.7 bits (239), Expect = 1e-20
Identities = 56/209 (26%), Positives = 119/209 (56%), Gaps = 12/209 (5%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRH-RERDRQTDREKERERQ 59
M RQ E+ RE + E RE ++ E+E E E R Q D+ R+ ++ ++E++ RQ
Sbjct: 533 MWRQEEKIREQE---EMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQ 589
Query: 60 KERDRQRQRER-ETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKG 118
+E+ R+++ +R E E + +Q E+ R++E K Q E+ ++++ + + + + +E+ K
Sbjct: 590 EEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKM 649
Query: 119 GRERDKQTERERDRERE-----RQRQRERERQRQRERKRETDRERQRWAEREERKKERKK 173
G + +K E+E + + RQ ++ RE++++ + E RE++ + +E K ++
Sbjct: 650 GEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE 709
Query: 174 ERKKERKEK--KKEEKRREDKKRKWGEGI 200
E+ E++EK ++EEK R +++ W + +
Sbjct: 710 EKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738
Score = 94.4 bits (233), Expect = 6e-20
Identities = 62/220 (28%), Positives = 122/220 (55%), Gaps = 25/220 (11%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
++ Q E+ RE + + E+ R++E + E RQ + E++ + R++E +K
Sbjct: 316 IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK 375
Query: 61 ERDRQRQRERETERETE--------RQRERQRQRERKRQTD---RERDKDRDRERK---- 105
E +RQ E E+E + ++E+ R++E KRQ + RE++K +++E K
Sbjct: 376 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 435
Query: 106 -----RETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETD---RE 157
+ ++ RE+ +K R+ +K E+E+ RE E+ RQ + E RQ E+ E + R+
Sbjct: 436 EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEK-RQEQEEMWRQEEKIHEQEEIWRQ 494
Query: 158 RQRWAEREER-KKERKKERKKERKEKKKEEKRREDKKRKW 196
+++ E+EE+ +K+ +K ++E K +++EEK RE +++ W
Sbjct: 495 KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMW 534
Score = 94.0 bits (232), Expect = 8e-20
Identities = 53/198 (26%), Positives = 118/198 (59%), Gaps = 7/198 (3%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDR-HRERDRQTDREKERERQK 60
E+ RE++++ R +E E+++ RE E + E+E RQ ++ H + + +EK E+++
Sbjct: 444 EKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEE 503
Query: 61 ERDRQRQRERETERETERQRERQRQRERK--RQTDRERDKD---RDRERKRETDRNRERN 115
+ +Q ++ E + Q E+ R++E K RQ ++ R+++ R+ E+ E ++ E
Sbjct: 504 KIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEE 563
Query: 116 RKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKER 175
++ +E + E+ RE+E + R+ E+ R++E KR+ ++E + W + E+ +++ +K +
Sbjct: 564 KRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQ-EQEEKMWKQEEKIREQEEKIQ 622
Query: 176 KKERKEKKKEEKRREDKK 193
++E K +++EEK RE ++
Sbjct: 623 EQEEKIREQEEKIREQEE 640
Score = 91.7 bits (226), Expect = 4e-19
Identities = 56/201 (27%), Positives = 120/201 (59%), Gaps = 10/201 (4%)
Query: 2 ERQRERK-RETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
+RQ E K RE ++ +E E + RQ E+ + E + R +++ R+ ++ ++EK RE +K
Sbjct: 412 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEK 471
Query: 61 ERDRQ---RQRERETERETE-RQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNR 116
++++ RQ E+ E+E RQ+E+ ++E K + E+ ++ + + + ++ RE+
Sbjct: 472 RQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEE 531
Query: 117 KGGRERDKQTERERD-RERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKER 175
K R+ +K E+E RE E+ ++E+ + E KR+ ++E + W + E+ +++ +K
Sbjct: 532 KMWRQEEKIREQEEMWREEEKMHEQEKIWE---EEKRQ-EQEDKMWRQEEKIREQEEKVW 587
Query: 176 KKERKEKKKEEKRREDKKRKW 196
++E K +++EEKR+E +++ W
Sbjct: 588 RQEEKIREQEEKRQEQEEKMW 608
Score = 89.7 bits (221), Expect = 1e-18
Identities = 53/212 (25%), Positives = 117/212 (55%), Gaps = 14/212 (6%)
Query: 1 MERQRE---RKRETDRGKET---ERERDRQRERENQTERENRHRQRDRHRERDRQTDREK 54
M RQ E K E R +E E+E +R+ E E+E + R+ + + ++
Sbjct: 351 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQE 410
Query: 55 ERERQKERDRQRQRERETERETERQRERQRQ-----RERKRQTDRERDKDRDRERKRETD 109
E+ +++E+ R++++ +E E + RQ E+ R+ RE++++ R+ +K ++E+ RE +
Sbjct: 411 EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE 470
Query: 110 RNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRE---RKRETDRERQRWAEREE 166
+ +E+ +E + E R++E+ ++E + ++Q E R+ E RE++ +E
Sbjct: 471 KRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQE 530
Query: 167 RKKERKKERKKERKEKKKEEKRREDKKRKWGE 198
K R++E+ +E++E +EE++ ++++ W E
Sbjct: 531 EKMWRQEEKIREQEEMWREEEKMHEQEKIWEE 562
Score = 88.2 bits (217), Expect = 4e-18
Identities = 62/213 (29%), Positives = 123/213 (57%), Gaps = 21/213 (9%)
Query: 1 MERQRERKRETDRG----KETERERDRQRERENQTERENRHRQRDRHRERD----RQTDR 52
M RQ E E + +E E+++ RE+E + + E + R++++ +E++ RQ ++
Sbjct: 379 MRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 438
Query: 53 EKERE---RQKERDRQRQRERETERETERQRE-RQRQRERKRQTDRERDKDRDRERKRET 108
+E+E R++E+ RQ E+ E+E R+ E RQ Q E RQ ++ +++ +K +
Sbjct: 439 IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKM 498
Query: 109 DRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAERE--- 165
E+ RK + +Q E+ R++E E+ R++E + RQ E+ RE + + W E E
Sbjct: 499 HEQEEKIRKQEEKVWRQEEKIREQE-EKIREQEEKMWRQEEKIRE---QEEMWREEEKMH 554
Query: 166 ERKKERKKERKKERKEK--KKEEKRREDKKRKW 196
E++K ++E+++E+++K ++EEK RE +++ W
Sbjct: 555 EQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVW 587
Score = 87.0 bits (214), Expect = 1e-17
Identities = 53/204 (25%), Positives = 112/204 (54%), Gaps = 13/204 (6%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
++ Q E +R + + E+ ++E + Q E Q ++ RE++ EK RE+++
Sbjct: 281 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE-----EKIREQEE 335
Query: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
+ RQ + E E + RQ E ++E K + E +++ + +R+ + E+ K
Sbjct: 336 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRE 395
Query: 121 ERDKQTERERDRERERQRQRE---RERQRQRERKRETDRERQRWAEREERKKERKK---- 173
+K E+E+ RE+E +RQ E RE+++++E++ + R+ ++ E+EE+ +E++K
Sbjct: 396 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWR 455
Query: 174 -ERKKERKEKKKEEKRREDKKRKW 196
E K +EK +EE++R++++ W
Sbjct: 456 QEEKIHEQEKIREEEKRQEQEEMW 479
Score = 86.7 bits (213), Expect = 1e-17
Identities = 54/214 (25%), Positives = 118/214 (55%), Gaps = 19/214 (8%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
E++ + +R+ + E E + RQ E + E + R + H + + EK +E +K
Sbjct: 360 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 419
Query: 62 RDRQRQRERETE--RETERQRERQRQ-RERKRQTDRERDKDRDRERKRETDRNRERNRKG 118
R++++++E+E + R+ E+ RE++ + RE++++ R+ +K ++E+ RE ++ +E+
Sbjct: 420 REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMW 479
Query: 119 GRERDKQTERERDRERERQRQRERERQRQRE---RKRETDRERQRWAEREERKKERKKER 175
+E + E R++E+ ++E + ++Q E R+ E RE++ +E K R++E+
Sbjct: 480 RQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEK 539
Query: 176 KKE-----RKEKK--------KEEKRREDKKRKW 196
+E R+E+K +EEKR+E + + W
Sbjct: 540 IREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMW 573
Score = 84.0 bits (206), Expect = 8e-17
Identities = 59/215 (27%), Positives = 127/215 (59%), Gaps = 22/215 (10%)
Query: 2 ERQRERKRETDRGKETERERD---RQRERENQTERENRH------RQRDRHRERDRQ-TD 51
E +R+ + E R +E E++ RQ+E+ ++ E + R RQ ++ RE++ + +
Sbjct: 469 EEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIRE 528
Query: 52 REKERERQKERDRQRQ---RERETERETERQRERQRQRERKRQTDRERDKDRDRERK--R 106
+E++ RQ+E+ R+++ RE E E E+ E ++++E++ + R+ +K R++E K R
Sbjct: 529 QEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWR 588
Query: 107 ETDRNRERNRKGGRERD---KQTERERDRERERQRQRERERQRQ---RERKRETDRERQR 160
+ ++ RE+ K + + KQ E+ R++E + Q Q E+ R+++ RE++ T + ++
Sbjct: 589 QEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEK 648
Query: 161 WAEREERK-KERKKERKKERKEKKKEEKRREDKKR 194
E+EE+ ++ +K +++E ++EEK RE +K+
Sbjct: 649 MGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKK 683
Score = 82.4 bits (202), Expect = 2e-16
Identities = 57/214 (26%), Positives = 113/214 (52%), Gaps = 17/214 (7%)
Query: 1 MERQRE---RKRETDRGKET---ERERDRQRERENQTERENRHRQRDRHRERDRQTDREK 54
M RQ E K E R +E E+E +R+ E E+E + R+++ + RE
Sbjct: 337 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 396
Query: 55 ERERQKERDRQRQRERETERETERQRERQRQRERK--RQTDRERDKD---RDRERKRETD 109
E + ++ + Q E+ E E R++E+++++E K RQ ++ R+++ R++E+K
Sbjct: 397 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQ 456
Query: 110 RNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETD-----RERQRWAER 164
+ ++ RE +K+ E+E +E + + E RQ+E+ E + +E + W +
Sbjct: 457 EEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQE 516
Query: 165 EERKKERKKERKKERKEKKKEEKRREDKKRKWGE 198
E+ +++ +K R++E K ++EEK RE ++ W E
Sbjct: 517 EKIREQEEKIREQEEKMWRQEEKIRE-QEEMWRE 549
Score = 80.1 bits (196), Expect = 1e-15
Identities = 42/196 (21%), Positives = 104/196 (53%), Gaps = 3/196 (1%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTEREN---RHRQRDRHRERDRQTDREKERER 58
E+ E+++ + K E+E R+ E E+E R ++ R +E RQ EK ++
Sbjct: 551 EKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ 610
Query: 59 QKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKG 118
+++ Q ++ +E E + Q E+ R++E Q E+ +++ + + ++ +E+
Sbjct: 611 EEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETM 670
Query: 119 GRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKE 178
R+ +K E+E+ + ++ RE+E Q + ++ ++E + + E+ +++ +K R++E
Sbjct: 671 WRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 730
Query: 179 RKEKKKEEKRREDKKR 194
K ++E + R+ +++
Sbjct: 731 EKMWEQEVRLRQQEEK 746
Score = 69.7 bits (169), Expect = 2e-12
Identities = 50/213 (23%), Positives = 106/213 (49%), Gaps = 24/213 (11%)
Query: 5 RERKRETDRGKETERERDRQRE-----RENQTERENRHRQRDRHRERDRQTDREKERERQ 59
+E KR+ +R K ++ Q E +E Q+ Q + + +R +++E+ +
Sbjct: 245 KELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWR 304
Query: 60 KERDRQRQRER--ETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRK 117
+E Q E+ E E + Q E+ R++E K + E +++ + +R+ + E+ K
Sbjct: 305 QEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 364
Query: 118 GGRERDKQTERERDRERERQRQRERERQ-RQRERKRETDRERQRWAEREERKKERKKERK 176
R+ + E+E R+ + E+E + R+ E K E+++ E+EE+++E +K R+
Sbjct: 365 MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH---EQEKIREQEEKRQEEEKIRE 421
Query: 177 KERKE-------------KKKEEKRREDKKRKW 196
+E+++ +++EEK RE +K+ W
Sbjct: 422 QEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW 454
Score = 57.4 bits (137), Expect = 8e-09
Identities = 38/182 (20%), Positives = 90/182 (49%), Gaps = 7/182 (3%)
Query: 19 RERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETER 78
+E R+ ER + + + H ++ Q+ K + + +E + + ++ E + R
Sbjct: 245 KELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWR 304
Query: 79 QRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQR 138
Q E+ ++ E K Q E+ ++++ ++ RE+ K R+ + E+E R+ +
Sbjct: 305 QEEKIQEWEEKIQEQEEKIREQE-------EKIREQEEKMRRQEEMMWEKEEKMRRQEEM 357
Query: 139 QRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGE 198
E+E + +R+ + ++E + + E ++ +K R+ E K ++E+ R +++KR+ E
Sbjct: 358 MWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEE 417
Query: 199 GI 200
I
Sbjct: 418 KI 419
Score = 51.6 bits (122), Expect = 4e-07
Identities = 44/200 (22%), Positives = 91/200 (45%), Gaps = 14/200 (7%)
Query: 6 ERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREK----ERERQKE 61
E R T +E + + + +E+ E E Q + +E R+ +R K +++ Q E
Sbjct: 208 ELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNV-KELKRKLERAKLLLPQQQLQAE 266
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRE---RDKDRDRERKRETDRNRERNRKG 118
D + + + + Q E R Q E R +++ +E + + E+ R+
Sbjct: 267 ADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQ 326
Query: 119 GRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQR-----WAEREERKKERKK 173
E+ ++ E + R+ E ++E + +RQ E E + + +R W + E+ +++ +
Sbjct: 327 -EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM 385
Query: 174 ERKKERKEKKKEEKRREDKK 193
+KE K ++ EEK E +K
Sbjct: 386 MWEKEEKIRELEEKMHEQEK 405
Score = 46.2 bits (108), Expect = 2e-05
Identities = 37/145 (25%), Positives = 72/145 (49%), Gaps = 7/145 (4%)
Query: 57 ERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNR 116
E KE++ + Q + + E+E+ + +E KR+ +R + ++ + E D + +
Sbjct: 217 EELKEKNAKLQEKLQLV-ESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ 275
Query: 117 KGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAE--REERKKERKKE 174
+ Q E E + +Q+E + RQ E+ +E + + Q E RE+ +K R++E
Sbjct: 276 SVSAKLQAQVE-ENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE 334
Query: 175 RKKERKEK---KKEEKRREDKKRKW 196
K R+E+ +KEEK R ++ W
Sbjct: 335 EKMRRQEEMMWEKEEKMRRQEEMMW 359
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 100 bits (248), Expect = 1e-21
Identities = 53/207 (25%), Positives = 94/207 (45%), Gaps = 7/207 (3%)
Query: 3 RQRERKRETDRGKETERERD-------RQRERENQTERENRHRQRDRHRERDRQTDREKE 55
R ++R + + +ERD R+ +Q+ N+ R R R ++ DR +
Sbjct: 357 RNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRS 416
Query: 56 RERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERN 115
R K RDR R R R+ R R + R+R R + +D R R R+R R+
Sbjct: 417 RSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRS 476
Query: 116 RKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKER 175
R +ERD +ER+ +R R ++RQ + R + +ER R K+ ++++
Sbjct: 477 RSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQS 536
Query: 176 KKERKEKKKEEKRREDKKRKWGEGISP 202
+ KE+ + + R ++R+ + SP
Sbjct: 537 RSPNKERDRSQSRSPSEEREHRQSRSP 563
Score = 97.8 bits (242), Expect = 5e-21
Identities = 53/198 (26%), Positives = 91/198 (45%), Gaps = 7/198 (3%)
Query: 3 RQRERKRETDRGKETERERDRQRERE-NQTERENRHRQRDRHRERDRQTDREKERERQ-- 59
R + R+ R + + RDR R R N+ +R R ++ R+R R KER+
Sbjct: 429 RSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQL 488
Query: 60 ----KERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERN 115
KERD +R R ER+ + R ++R+ +R +++ R + R +R+R ++
Sbjct: 489 GSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQS 548
Query: 116 RKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKER 175
R ER+ + R +ER+R+R R ++R+R + R + ER R K+
Sbjct: 549 RSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRP 608
Query: 176 KKERKEKKKEEKRREDKK 193
+ KEK R K+
Sbjct: 609 RASSKEKAHSRSRTPSKE 626
Score = 97.1 bits (240), Expect = 9e-21
Identities = 52/196 (26%), Positives = 90/196 (45%), Gaps = 6/196 (3%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERE-NRHRQRDRHRERDRQTDREKERERQKE 61
R R R R ++ ++ R R + R+ R N+ R R R ++ DR + R KE
Sbjct: 423 RDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKE 482
Query: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
RD + ER+ R R ++R+ ++ +++D R R +R R ++R +E
Sbjct: 483 RDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKE 542
Query: 122 RDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKE 181
RD+ R ERE ++ R ++R R R R +ER+R R+ R +++ + R
Sbjct: 543 RDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERER---RQSRSSSEERDHSRSRSP 599
Query: 182 KKKE--EKRREDKKRK 195
K+ + R K K
Sbjct: 600 NKQSGYSRPRASSKEK 615
Score = 96.3 bits (238), Expect = 2e-20
Identities = 49/202 (24%), Positives = 90/202 (44%), Gaps = 1/202 (0%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERE-NRHRQRDRHRERDRQTDREKERERQK 60
+R R R ++ ++ R R + R+ R N+ R R R + DR + R K
Sbjct: 398 QRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNK 457
Query: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
RD R R R+ R R ++R+ + +++D R R +R ++R +
Sbjct: 458 ARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSK 517
Query: 121 ERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERK 180
ERD + R +ER+R++ R ++R R + R ER+ R K+ ++ + K
Sbjct: 518 ERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSK 577
Query: 181 EKKKEEKRREDKKRKWGEGISP 202
E+++ + R ++R SP
Sbjct: 578 ERERRQSRSSSEERDHSRSRSP 599
Score = 92.0 bits (227), Expect = 3e-19
Identities = 53/199 (26%), Positives = 92/199 (46%), Gaps = 9/199 (4%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQT------DREKER 56
R + R+ R + + RD R R R+ R R R +ERD +R+ R
Sbjct: 441 RSPYKARDRSRSRSPNKARDHSRSRSPNKARD-RSRSRSPSKERDHSQLGSPSKERDHRR 499
Query: 57 ERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRE--R 114
R ++RQ ++ R + +E + +R R +ER+R+ R +K+RDR + R RE +
Sbjct: 500 SRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQ 559
Query: 115 NRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKE 174
+R +ERD++ R +ERER++ R +R R R +++ R K++
Sbjct: 560 SRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSR 619
Query: 175 RKKERKEKKKEEKRREDKK 193
+ KE + R K+
Sbjct: 620 SRTPSKEGNHSQSRTSSKE 638
Score = 83.2 bits (204), Expect = 1e-16
Identities = 42/149 (28%), Positives = 75/149 (50%), Gaps = 1/149 (0%)
Query: 7 RKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQR 66
++R+ R + +ER ++ R + ER++R R R +ER R+ R +ER + + R
Sbjct: 493 KERDHRRSRSPSKERQCRQSRSSSKERDHR-RSRSPSKERQRRQSRSPNKERDRSQSRSP 551
Query: 67 QRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQT 126
ERE + +ER R+R R +RER + R +R+ R+R N++ G R + +
Sbjct: 552 SEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRAS 611
Query: 127 ERERDRERERQRQRERERQRQRERKRETD 155
+E+ R R +E + R +E+D
Sbjct: 612 SKEKAHSRSRTPSKEGNHSQSRTSSKESD 640
Score = 79.0 bits (193), Expect = 3e-15
Identities = 49/197 (24%), Positives = 87/197 (44%), Gaps = 7/197 (3%)
Query: 3 RQRERKRETDRGK--ETERERDRQRERENQTERENRHRQRDRHRERDRQTDRE--KERER 58
R R +E D + +ERD +R R ER+ R + R +ERD + R KER+R
Sbjct: 475 RSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCR-QSRSSSKERDHRRSRSPSKERQR 533
Query: 59 QKERDRQRQRERETERETERQRERQRQRERKRQTDRER--DKDRDRERKRETDRNRERNR 116
++ R ++R+R R +RE ++ R ++ DR R ++RER++ + ER+
Sbjct: 534 RQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDH 593
Query: 117 KGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERK 176
R +KQ+ R R +++ R R +E R + ++ + R + K
Sbjct: 594 SRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWK 653
Query: 177 KERKEKKKEEKRREDKK 193
+ + R K
Sbjct: 654 RSPTRTSSLSQNRTPSK 670
Score = 78.2 bits (191), Expect = 4e-15
Identities = 52/212 (24%), Positives = 86/212 (40%), Gaps = 13/212 (6%)
Query: 4 QRERKRETDRGKETERERDRQRERENQTERE-NRHRQRDRHRERDRQTDREKERERQKER 62
+ + R +GK + R +R R + R ++ R R ++ D +KE
Sbjct: 328 RHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKES 387
Query: 63 DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRER 122
R + +R+ R R + R+R R + +DR R R R+ R+R + R
Sbjct: 388 GRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKAR 447
Query: 123 DKQTERERDRERERQRQRERERQRQRERKRETDRER---QRWAEREERKKERKKERKKER 179
D+ R ++ R+ R R + R R R R +ER Q + +ER R + KER
Sbjct: 448 DRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKER 507
Query: 180 ---------KEKKKEEKRREDKKRKWGEGISP 202
KE+ R K+R+ + SP
Sbjct: 508 QCRQSRSSSKERDHRRSRSPSKERQRRQSRSP 539
Score = 77.8 bits (190), Expect = 6e-15
Identities = 55/215 (25%), Positives = 89/215 (41%), Gaps = 15/215 (6%)
Query: 3 RQRERKRE---TDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQ 59
R R R R+ + G+ ++ + + +NQ+ R R + R ++ R
Sbjct: 313 RARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSS 372
Query: 60 KERDRQ--RQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRK 117
KERD + +E+ R +QR R R ++ RD+ R R + DR+R R+
Sbjct: 373 KERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPN 432
Query: 118 GGRE--RDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAERE-------ERK 168
R+ R + + RDR R R + R+ R R + DR R R +E
Sbjct: 433 KARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPS 492
Query: 169 KERKKERKKE-RKEKKKEEKRREDKKRKWGEGISP 202
KER R + KE++ + R K+R SP
Sbjct: 493 KERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSP 527
Score = 77.4 bits (189), Expect = 8e-15
Identities = 45/189 (23%), Positives = 84/189 (44%), Gaps = 11/189 (5%)
Query: 3 RQRERKRETDRGKETERERDRQ------RERENQTERE-NRHRQRDRHRERDRQTDREKE 55
R + R+ R + +ERD +ER+++ R ++ RQ + R ++ D +
Sbjct: 465 RSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRS 524
Query: 56 RERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERN 115
R KER R++ R ER+ + R +RE ++ +++DR R R +R R ++
Sbjct: 525 RSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQS 584
Query: 116 RKGGRERDKQTERERDRE----RERQRQRERERQRQRERKRETDRERQRWAEREERKKER 171
R ERD R +++ R R +E+ R R +E + + R + +E +
Sbjct: 585 RSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQS 644
Query: 172 KKERKKERK 180
R + K
Sbjct: 645 TVPRSPDWK 653
Score = 51.2 bits (121), Expect = 6e-07
Identities = 35/183 (19%), Positives = 66/183 (36%), Gaps = 6/183 (3%)
Query: 26 ERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQ 85
E ++ + N+ R R + + + R ++R R R +R R R R R+
Sbjct: 261 EMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRK 320
Query: 86 ----RERKRQTDRERDKDRDRERKRETDRNRERN--RKGGRERDKQTERERDRERERQRQ 139
+ + R K + + + R R R N R +ER R +ER+ +
Sbjct: 321 GILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGS 380
Query: 140 RERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGEG 199
++ R + +++R R K + + K + + R +K R
Sbjct: 381 SSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRS 440
Query: 200 ISP 202
SP
Sbjct: 441 RSP 443
Score = 50.8 bits (120), Expect = 8e-07
Identities = 35/195 (17%), Positives = 72/195 (36%), Gaps = 23/195 (11%)
Query: 24 QRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETE---------- 73
Q ++ + ++ R R R ++ + R +R+ R R R +
Sbjct: 271 QASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHS 330
Query: 74 ------RETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRER------NRKGGRE 121
+ + + R +R R R K+R R + + R+ ++ GR
Sbjct: 331 QSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRS 390
Query: 122 RDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAER-EERKKERKKERKKERK 180
+ ++RD R R + R+R R R + DR R R + + + R + ++R
Sbjct: 391 QSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRS 450
Query: 181 EKKKEEKRREDKKRK 195
+ K R+ + +
Sbjct: 451 RSRSPNKARDHSRSR 465
Score = 44.3 bits (103), Expect = 7e-05
Identities = 32/167 (19%), Positives = 57/167 (34%), Gaps = 4/167 (2%)
Query: 40 RDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKD 99
R++ + R K + R R + + R ++R R R +R+
Sbjct: 253 REKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHS 312
Query: 100 RDRERKRETDRNRERNRKGGRERDKQTERERDRERERQR----QRERERQRQRERKRETD 155
R R R R+ ++ R K + + R R R R ++R R +
Sbjct: 313 RARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSS 372
Query: 156 RERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGEGISP 202
+ER RK+ + + K++ R +K R SP
Sbjct: 373 KERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSP 419
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 100 bits (248), Expect = 1e-21
Identities = 66/218 (30%), Positives = 123/218 (56%), Gaps = 23/218 (10%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRH-RERDRQTDREKERERQ 59
M RQ ER RE + GK E+E +R+ + E+E R++++ RE+ + ++E++ + Q
Sbjct: 257 MWRQEERLREQE-GKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQ 315
Query: 60 KER-----DRQRQRERETERETER---QRERQRQRERKRQTDRERDKDRDRERKRETDRN 111
+E+ ++ R++E + R+ ER Q ++ R++E+K + ER ++D ER RE +
Sbjct: 316 EEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQD-ERLREKEER 374
Query: 112 RERNRKGGRERDKQTERERDRERERQRQRERERQRQRERK-----------RETDRERQR 160
K + +K E ER RERE++ + E E R++E K E + ++QR
Sbjct: 375 MREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQR 434
Query: 161 WAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGE 198
E++E+ E++K +++E K ++EEK R D++ WG+
Sbjct: 435 LPEQKEKLWEQEKMQEQEEKIWEQEEKIR-DQEEMWGQ 471
Score = 99.8 bits (247), Expect = 1e-21
Identities = 58/203 (28%), Positives = 120/203 (59%), Gaps = 9/203 (4%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
M Q ER E D + + +R RE+E E+E + ++ +R RER+++ E+E R++
Sbjct: 354 MRDQEERMWEQD--ERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQ 411
Query: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
E Q+Q E E+E + ++++ ++++ ++E+ ++++ + + ++ R++ G+
Sbjct: 412 EEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQ 471
Query: 121 ERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWA--EREERKKERKKERKK- 177
E+ K +E+ RE+E Q + E+ R +E+K D+E + W ER K+ER +E+KK
Sbjct: 472 EK-KMWRQEKMREQEDQMWEQEEKMRDQEQKM-WDQEERMWEQDERLREKEERMREQKKM 529
Query: 178 -ERKEKKKEEKR-REDKKRKWGE 198
+++EK +EEK+ +E +K+ W +
Sbjct: 530 WQQEEKMREEKKTQEQEKKTWDQ 552
Score = 95.5 bits (236), Expect = 3e-20
Identities = 63/222 (28%), Positives = 125/222 (56%), Gaps = 28/222 (12%)
Query: 2 ERQRERKRETDRGKETERERDR--QRERENQTERENRHRQRDRHRE-RDRQTDREKERER 58
ER RER+++ +ET RE++ Q++ EN E+E + Q+ R E +++ ++EK +E+
Sbjct: 392 ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 451
Query: 59 QKE--------RDRQ-----------RQRERETERETERQRERQRQRERKRQTDRERDKD 99
+++ RD++ +++ RE E + Q E+ R +E+K ER +
Sbjct: 452 EEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWE 511
Query: 100 RDRERKRETDRNRERNRKGGRERDKQTERERDRERER----QRQRERERQRQRERKRETD 155
+D ER RE + +K ++ +K E ++ +E+E+ Q ++ RE +R RER+++
Sbjct: 512 QD-ERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMR 570
Query: 156 RERQRWAEREERKKER-KKERKKERKEKKKEEKRREDKKRKW 196
E + E+EE+ +E+ +K R++E K ++EEK +E +++ W
Sbjct: 571 EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW 612
Score = 95.5 bits (236), Expect = 3e-20
Identities = 48/198 (24%), Positives = 118/198 (59%), Gaps = 5/198 (2%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
+++ R++E ++ E+ RD++++ +Q ER Q +R RE++ + +K+ +Q+E+
Sbjct: 478 QEKMREQEDQMWEQEEKMRDQEQKMWDQEER--MWEQDERLREKEERMREQKKMWQQEEK 535
Query: 63 DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRER 122
R+ ++ +E E++T Q E+ R+ ER R+ +++ ++ + R++E ++ +E+ K +
Sbjct: 536 MREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE-EKMQEQEEKMREQE 594
Query: 123 DKQTERERDRERERQRQRERERQ--RQRERKRETDRERQRWAEREERKKERKKERKKERK 180
+K E+E + + ++ E+E + Q E + ++E W + E+ +++ +K ++E K
Sbjct: 595 EKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK 654
Query: 181 EKKKEEKRREDKKRKWGE 198
+++EEK RE +++ G+
Sbjct: 655 MREQEEKMREQEEKMQGQ 672
Score = 95.1 bits (235), Expect = 4e-20
Identities = 50/204 (24%), Positives = 113/204 (55%), Gaps = 11/204 (5%)
Query: 1 MERQRERKRETDRGKETERER-----DRQRERENQT-ERENRHRQRDRHRERDRQTDREK 54
M Q E+ R+ ++ + ER +R RE+E + E++ +Q ++ RE + ++EK
Sbjct: 488 MWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEK 547
Query: 55 ERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRER 114
+ Q+E+ R+ +R RE E++ + E R++E K Q E+ ++++ + + ++ +E+
Sbjct: 548 KTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ 607
Query: 115 NRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKE 174
K + +K E+E E + +E+E + ++ ++E + W + E+ +++ +K
Sbjct: 608 EEKMWEQEEKMWEQE-----EEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKM 662
Query: 175 RKKERKEKKKEEKRREDKKRKWGE 198
R++E K + +EEK RE +++ G+
Sbjct: 663 REQEEKMQGQEEKMREQEEKMQGQ 686
Score = 95.1 bits (235), Expect = 4e-20
Identities = 50/201 (24%), Positives = 106/201 (52%), Gaps = 4/201 (1%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
ER RE+K+ + ++ E+ Q + + ++E + R+ +R RER+++ E+E R++E
Sbjct: 521 ERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 580
Query: 62 RDRQRQRE--RETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNR--ERNRK 117
Q Q E RE E + Q E+ +++E K E+ +++ E K + E+ K
Sbjct: 581 EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEK 640
Query: 118 GGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKK 177
+ +K E+E + ++ RE+E + Q + ++ ++E + + E+ +++ +K R +
Sbjct: 641 MQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQ 700
Query: 178 ERKEKKKEEKRREDKKRKWGE 198
E K +EEK +++ WG+
Sbjct: 701 EEKMWGQEEKMWGQEEKMWGQ 721
Score = 92.8 bits (229), Expect = 2e-19
Identities = 55/205 (26%), Positives = 120/205 (58%), Gaps = 16/205 (7%)
Query: 5 RERKRETDRGK---------ETERERDRQRERENQTERENRHRQRDRHRERDRQTDRE-K 54
+E KR+ +R K + E RQ E + E++ R ++ R+ +R ++E K
Sbjct: 211 KELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGK 270
Query: 55 ERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRER 114
RE++++ RQ +R RE E+E R++E++ + ++K + E+ ++++ + + ++ RE+
Sbjct: 271 MREQEEKMRRQEKRLREQEKEL-REQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQ 329
Query: 115 NRKGGRERDKQTERERDRERERQRQRERERQ--RQRERKRETD---RERQRWAEREERKK 169
K R+ ++ E+E+ + Q+ R++E + Q ER RE + RE+++ E+EE+ +
Sbjct: 330 EEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQ 389
Query: 170 ERKKERKKERKEKKKEEKRREDKKR 194
E ++ R++E+K +++EE RE +++
Sbjct: 390 EEERIREREKKMREEEETMREQEEK 414
Score = 92.8 bits (229), Expect = 2e-19
Identities = 53/208 (25%), Positives = 114/208 (54%), Gaps = 19/208 (9%)
Query: 1 MERQRERKRETDRGKETER----ERDRQRERENQTERENRHRQRDRHRERDRQTDREKER 56
+ Q+E+ E ++ +E E + ++ R++E +E + ++++ RE++ Q ++E+
Sbjct: 435 LPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 494
Query: 57 ERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNR 116
R +E+ Q ER E++ + + +R RE+K+ +E E+ RE + +E+ +
Sbjct: 495 MRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQE-------EKMREEKKTQEQEK 547
Query: 117 KGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQR------WAEREERKKE 170
K + +K E ER RERE++ + E E R++E K + E+ R W + E+ +++
Sbjct: 548 KTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ 607
Query: 171 RKKERKKERK--EKKKEEKRREDKKRKW 196
+K ++E K E+++E+K +E ++ W
Sbjct: 608 EEKMWEQEEKMWEQEEEDKMQEQEEMMW 635
Score = 92.0 bits (227), Expect = 3e-19
Identities = 53/206 (25%), Positives = 112/206 (54%), Gaps = 14/206 (6%)
Query: 4 QRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERD 63
Q ER E D + + +R RE++ ++E + R+ + +E++++T ++E+ R++ER
Sbjct: 505 QEERMWEQD--ERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERM 562
Query: 64 RQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDR---NRERNRKGGR 120
R+R+++ E E R++E + Q + ++ ++E E+ +E + +E
Sbjct: 563 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 622
Query: 121 ERDKQTERER---DRERERQRQRER-----ERQRQRERKRETDRERQRWAEREERKKERK 172
E DK E+E ++E + Q Q E+ E+ R++E K E+ + E + R++E K
Sbjct: 623 EEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEK 682
Query: 173 KERKKERKEKKKEEKRREDKKRKWGE 198
+ ++E K +++EEK R +++ WG+
Sbjct: 683 MQGQEE-KMREQEEKMRGQEEKMWGQ 707
Score = 91.7 bits (226), Expect = 4e-19
Identities = 56/199 (28%), Positives = 116/199 (58%), Gaps = 10/199 (5%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREK----ER 56
M Q ++ R+ + + ER R++E E E+E Q ++ +E +R +REK E
Sbjct: 347 MREQEQKMRDQEERMWEQDERLREKE-ERMREQEKMWEQEEKMQEEERIREREKKMREEE 405
Query: 57 ERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERK--RETDRNRER 114
E +E++ + Q++ E E E + +Q++ +++ E++K +++E K + ++ R++
Sbjct: 406 ETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ 465
Query: 115 NRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKE 174
G+E+ K +E+ RE+E Q + E+ R +E+K D+E + W E++ER +E+++
Sbjct: 466 EEMWGQEK-KMWRQEKMREQEDQMWEQEEKMRDQEQKM-WDQEERMW-EQDERLREKEER 522
Query: 175 RKKERKEKKKEEKRREDKK 193
++++K ++EEK RE+KK
Sbjct: 523 MREQKKMWQQEEKMREEKK 541
Score = 90.9 bits (224), Expect = 7e-19
Identities = 56/199 (28%), Positives = 113/199 (56%), Gaps = 7/199 (3%)
Query: 1 MERQRERKRETDRG-KETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQ 59
M RQ E RE ++ ++ E + RQ ER + E + R ++ R+ R ++EKE Q
Sbjct: 236 MWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQ 295
Query: 60 KERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
++ R++++ RE E + + Q E+ ++E K + ++E R ER E ++ +
Sbjct: 296 EKELREQKKLREQEEQMQEQEEKMWEQEEKMR-EQEEKMWRQEERLWEQEKQMREQEQKM 354
Query: 120 RERDKQTERERDRERERQ-RQRERERQRQRERKRETDRERQRWAEREERKKERKKE-RKK 177
R+++++ + +R RE++ R RE+E+ ++E K + E +R ERE++ +E ++ R++
Sbjct: 355 RDQEERMWEQDERLREKEERMREQEKMWEQEEKMQ---EEERIREREKKMREEEETMREQ 411
Query: 178 ERKEKKKEEKRREDKKRKW 196
E K +K+EE E ++++W
Sbjct: 412 EEKMQKQEENMWEQEEKEW 430
Score = 87.8 bits (216), Expect = 6e-18
Identities = 50/204 (24%), Positives = 121/204 (59%), Gaps = 8/204 (3%)
Query: 2 ERQRERKRETDRGKETERER-DRQRERENQTERENRHRQRDRHRERDRQTDREKER-ERQ 59
+ ++ R +E G+E + R ++ RE+E+Q E + RD+ ++ Q +R E+ ER
Sbjct: 458 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW-EQEEKMRDQEQKMWDQEERMWEQDERL 516
Query: 60 KERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
+E++ + + +++ ++ E+ RE ++ +E++++T + +K R+ ER RE ++ +
Sbjct: 517 REKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM 576
Query: 120 RERDKQTERERDRERERQRQR-ERERQRQRERKRETDRERQRWAEREERKKERKKERKKE 178
RE++++ + + ++ RE++ + E+E + Q + ++ ++E + W + EE K + ++E E
Sbjct: 577 REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWE 636
Query: 179 RKEKKKEEKRR----EDKKRKWGE 198
++EK +E++ + E+K R+ E
Sbjct: 637 QEEKMQEQEEKMWEQEEKMREQEE 660
Score = 87.0 bits (214), Expect = 1e-17
Identities = 50/204 (24%), Positives = 112/204 (54%), Gaps = 10/204 (4%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRH-RQRDRHRERDRQTDREKERERQK 60
ER RE++ K+ ++ ++ RE + E+E + Q ++ RE +R RE+E++ ++
Sbjct: 514 ERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERM--REREKKMRE 571
Query: 61 ERDRQRQRERETERETERQRERQR---QRERKRQTDRER--DKDRDRERKRETDRNRERN 115
E + R++E + + + E+ RE++ ++E K Q E+ +++ + E D+ +E+
Sbjct: 572 EEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQE 631
Query: 116 RKGGRERDKQTERERDR-ERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKE 174
+ +K E+E E+E + + + E+ R++E K + E+ R + E+ + + +K
Sbjct: 632 EMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR-EQEEKMQGQEEKM 690
Query: 175 RKKERKEKKKEEKRREDKKRKWGE 198
R++E K + +EEK +++ WG+
Sbjct: 691 REQEEKMRGQEEKMWGQEEKMWGQ 714
Score = 85.5 bits (210), Expect = 3e-17
Identities = 46/192 (23%), Positives = 110/192 (57%), Gaps = 11/192 (5%)
Query: 15 KETERERDRQR----ERENQTERENRHRQRDRHRERDRQTDREKERE-RQKERDRQRQRE 69
KE +R+ +R + + + T +E RQ + RE++++ +++E+ RQ+ER R+++ +
Sbjct: 211 KELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGK 270
Query: 70 RETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERE 129
+ E R++E++ + + K ++E++ ++ + + ++ +E+ K + +K E+E
Sbjct: 271 MREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQE 330
Query: 130 RDRERERQRQRERERQRQRERKRETDRERQRWA------EREERKKERKKERKKERKEKK 183
R+ +R E+E+Q + + ++ D+E + W E+EER +E++K ++E K ++
Sbjct: 331 EKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQE 390
Query: 184 KEEKRREDKKRK 195
+E R +KK +
Sbjct: 391 EERIREREKKMR 402
Score = 83.2 bits (204), Expect = 1e-16
Identities = 47/199 (23%), Positives = 105/199 (52%), Gaps = 11/199 (5%)
Query: 4 QRERKRETDRGKETERERDRQRERENQTERENR-HRQRDRHRERDRQTDREKERERQKER 62
Q E+ RE +R +E RE+ + E E E+E + Q ++ RE++ + ++E+ +++E
Sbjct: 552 QEEKMREEERMRE--REKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609
Query: 63 DRQRQRERETERETE----RQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKG 118
Q E+ E+E E Q E ++E K Q E+ +++ + + + ++ RE+ K
Sbjct: 610 KMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKM 669
Query: 119 GRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAERE----ERKKERKKE 174
+ +K E+E + + ++ RE+E + + + ++ +E + W + E + + K+E
Sbjct: 670 QGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEE 729
Query: 175 RKKERKEKKKEEKRREDKK 193
R +++KEK +E +++
Sbjct: 730 RIRDQKEKMQERLPEHEER 748
Score = 72.0 bits (175), Expect = 3e-13
Identities = 46/196 (23%), Positives = 101/196 (51%), Gaps = 9/196 (4%)
Query: 6 ERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREK-------ERER 58
E R T +E +++ +E+ E E Q + +E R+ +R K
Sbjct: 174 ELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNV-KELKRKLERAKFLLPQVQTNTL 232
Query: 59 QKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKG 118
Q+E RQ + RE E++ +Q E+ ++E + + + ++++ + +R+ R RE+ ++
Sbjct: 233 QEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKEL 292
Query: 119 GRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKE 178
+ + E+++ RE+E Q Q + E+ ++E K ++E + W + E ++ K+ R++E
Sbjct: 293 REQEKELREQKKLREQEEQMQEQEEKMWEQEEKMR-EQEEKMWRQEERLWEQEKQMREQE 351
Query: 179 RKEKKKEEKRREDKKR 194
+K + +EE+ E +R
Sbjct: 352 QKMRDQEERMWEQDER 367
Score = 63.5 bits (153), Expect = 1e-10
Identities = 45/158 (28%), Positives = 89/158 (56%), Gaps = 7/158 (4%)
Query: 46 RDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRER-KRQTDRERDKDRDRER 104
R+ T+ E +++ + +++ R E E +E +R+ ER K + + E
Sbjct: 177 RNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEM 236
Query: 105 KRETDRNRERNRKGGRERDKQ-TERERDRERE-RQRQRERERQRQRERKRETDRE-RQRW 161
R+ + RE+ +K ++ +K + ER RE+E + R++E + +RQ +R RE ++E R++
Sbjct: 237 WRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQE 296
Query: 162 AEREERKKERKKERKKERKEKK---KEEKRREDKKRKW 196
E E+KK R++E + + +E+K +EEK RE +++ W
Sbjct: 297 KELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMW 334
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 99.8 bits (247), Expect = 1e-21
Identities = 53/203 (26%), Positives = 109/203 (53%), Gaps = 13/203 (6%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERE----- 57
+ + +KR + + +E+ + +ER+++ R R R R + RD + +EKE++
Sbjct: 449 KNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKG 508
Query: 58 RQKERDRQRQRERETE-RETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNR 116
+ +ER R +++ ++ E + E + ++++R+ Q+ R R+ D + + R RER+R
Sbjct: 509 KDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQS-RSRECDITKGKHSYNSRTRERSR 567
Query: 117 ---KGGRERDKQTERERDRERERQRQRERE---RQRQRERKRETDRERQRWAEREERKKE 170
+ R R + +R+R R +E R RE+E R R R R+R T R R +R R+++
Sbjct: 568 SRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRD 627
Query: 171 RKKERKKERKEKKKEEKRREDKK 193
+ ++E + + K++ R ++ K
Sbjct: 628 SRSSEREESQSRNKDKYRNQESK 650
Score = 94.4 bits (233), Expect = 6e-20
Identities = 57/213 (26%), Positives = 105/213 (49%), Gaps = 23/213 (10%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE- 61
R+ E++++ K +ERD +R E + +N+ ++R + + R + ++ K +ER +
Sbjct: 418 RKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKH 477
Query: 62 --------RDRQRQRERETERETERQ-------RERQRQRERKRQTDRERDKDRDRERKR 106
R R + R+ E +E E+Q +ER R +E+ +Q + + + D + +
Sbjct: 478 NRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLE-SKSNEHDHSKSK 536
Query: 107 ETDRNRE-RNRKGGRERDKQTERERDRERERQRQRERE-RQRQRERKRETDRERQRWAER 164
E DR + R+R+ + K + R RER R R R R R R +R R +E R+ E+
Sbjct: 537 EKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQ 596
Query: 165 EERKKERKKERKKE----RKEKKKEEKRREDKK 193
E R++ R + R++ R K +RR D +
Sbjct: 597 EYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSR 629
Score = 92.4 bits (228), Expect = 2e-19
Identities = 60/207 (28%), Positives = 97/207 (46%), Gaps = 18/207 (8%)
Query: 3 RQRERKRETDRGKETE---RERDRQRERENQTERENRHRQRD----------RHRERDRQ 49
+ +ER R ++ K+ E E D + +E ++R R+ D R RER R
Sbjct: 509 KDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRS 568
Query: 50 TDREKE-RERQKERDRQRQRERETERETE-RQRERQRQRERKRQTDRERDKDRDRERKRE 107
DR + R R +RDR R +E RE E R+R R R RER+ R R K DR R+R
Sbjct: 569 RDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSK--DRRRRRR 626
Query: 108 TDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRER-KRETDRERQRWAEREE 166
R+ ER R +DK +E ++ +R + R ++ R++ A+R++
Sbjct: 627 DSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQ 686
Query: 167 RKKERKKERKKERKEKKKEEKRREDKK 193
+ K+ ++ + K K +ED+K
Sbjct: 687 SPFSKIKQSSQDNELKSSMLKNKEDEK 713
Score = 90.9 bits (224), Expect = 7e-19
Identities = 53/207 (25%), Positives = 97/207 (46%), Gaps = 8/207 (3%)
Query: 3 RQRERKRETD--RGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
R + R RE D +GK + R R+R R R R R DR R R ++ R +E+E +
Sbjct: 541 RAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQE-YR 599
Query: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
R R R RER T R ++R+R+R R ++RE + R++++ R + ++
Sbjct: 600 RRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSE 659
Query: 121 ERDKQTERERD-----RERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKER 175
+ + RD RE++ R++ + ++ + + + + +E +K R
Sbjct: 660 SEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVE 719
Query: 176 KKERKEKKKEEKRREDKKRKWGEGISP 202
K+ +K K +E +K +K+ SP
Sbjct: 720 KENQKSKGQENDHVHEKNKKFDHESSP 746
Score = 90.1 bits (222), Expect = 1e-18
Identities = 56/205 (27%), Positives = 101/205 (49%), Gaps = 16/205 (7%)
Query: 4 QRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTD---REKERERQK 60
+ E KR R K R+ + +E+E Q++ + + ++R R +E+ +Q + E + + K
Sbjct: 479 RNEEKRMRSRSKG--RDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSK 536
Query: 61 ERDRQRQ-RERETE------RETERQRERQRQRERKRQT---DRERDKDRDRERKRETDR 110
E+DR+ Q R RE + R RER R R+R R+ +RD+ R +E R ++
Sbjct: 537 EKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQ 596
Query: 111 N-RERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKK 169
R R R RER R R ++R R+R+ R +R+ + R D+ R + ++ RK+
Sbjct: 597 EYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKE 656
Query: 170 ERKKERKKERKEKKKEEKRREDKKR 194
+ E++ K + +K+
Sbjct: 657 NSESEKRMYSKSRDHNSSNNSREKK 681
Score = 88.6 bits (218), Expect = 3e-18
Identities = 53/212 (25%), Positives = 100/212 (47%), Gaps = 22/212 (10%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTD---------- 51
E +E+++++D K ++ER R +E+ Q E ++ + +E+DR+
Sbjct: 495 ENVKEKEKQSD-SKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITK 553
Query: 52 -----REKERERQKERDRQRQ-RERETERETERQRERQRQRERKRQTDRERDKDRDRERK 105
+ RER + RDR R+ R R +R+ R +E R RE Q R R + R RER+
Sbjct: 554 GKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYRE---QEYRRRGRSRSRERR 610
Query: 106 RETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAERE 165
R+R ++R+ R + +ERE + R + + R +E + ++ +R R+
Sbjct: 611 TPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRD 670
Query: 166 ERKKERKKERKKERKEK--KKEEKRREDKKRK 195
+E+K +R + K ++ +D + K
Sbjct: 671 HNSSNNSREKKADRDQSPFSKIKQSSQDNELK 702
Score = 82.0 bits (201), Expect = 3e-16
Identities = 57/219 (26%), Positives = 105/219 (47%), Gaps = 22/219 (10%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTEREN-RHRQRDRHRERD-RQTDREKERERQK 60
R +ERK R R ++E++ + + N + R R+ E+D + ++ K+R + K
Sbjct: 400 RVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSK 459
Query: 61 ERDRQRQRERETERETERQR-ERQRQRERKRQTDRER---------DKDRDRERKRETDR 110
R + +++ + ER+++ R E +R R R + D E K +D+ER R ++
Sbjct: 460 SRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEK 519
Query: 111 NRERNRKGGRERDKQTERERDRERERQRQRERE--------RQRQRERKRETDRERQRWA 162
+++ K E D +E+DR R + R RE + R RER R DR R+ +
Sbjct: 520 SKQLESK-SNEHDHSKSKEKDR-RAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRS 577
Query: 163 EREERKKERKKERKKERKEKKKEEKRREDKKRKWGEGIS 201
+R + R KE + R+++ + R ++R+ G S
Sbjct: 578 RTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRS 616
Score = 75.1 bits (183), Expect = 4e-14
Identities = 49/199 (24%), Positives = 96/199 (48%), Gaps = 17/199 (8%)
Query: 13 RGKETERERDRQRERENQT----ERENRHRQRDRHRERDRQTDREKE-----RERQKERD 63
R + R R R R R ++T +E + QR R +R +K +E Q+
Sbjct: 340 RYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPV 399
Query: 64 RQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETD---RNRERNRKGGR 120
R ++R+ R R+ ++E+K + + K+RD R E D +N+ + R +
Sbjct: 400 RVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSK 459
Query: 121 ERDKQTERERDRERERQRQR-ERERQRQRERKRE----TDRERQRWAEREERKKERKKER 175
R K E+ + +ER+ + R E +R R R + R+ ++E+Q ++ +++++ R KE+
Sbjct: 460 SRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEK 519
Query: 176 KKERKEKKKEEKRREDKKR 194
K+ + K E + K++
Sbjct: 520 SKQLESKSNEHDHSKSKEK 538
Score = 72.4 bits (176), Expect = 2e-13
Identities = 46/212 (21%), Positives = 101/212 (47%), Gaps = 20/212 (9%)
Query: 2 ERQRERKRETDRG----KETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERE 57
E QR ++ G K + E + +E + R + D HR +R+ E+E
Sbjct: 365 EMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITD-HRNVSESPNRKNEKE 423
Query: 58 RQKERDRQRQRERETERETERQ---RERQRQRERKRQTDRERDKDRDRERKRETDRNRE- 113
++ + + +ER+ R +E+ + + ++R + + + ++K + +ER + +RN E
Sbjct: 424 KKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEK 483
Query: 114 --RNRKGGRERDKQTERERDRE---RERQRQRERERQRQRERKRETDRERQRWAEREERK 168
R+R GR+ + E+E+ + ++++R R +E+ +Q E K + + + E++ R
Sbjct: 484 RMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESK-SNEHDHSKSKEKDRRA 542
Query: 169 KERKKE-----RKKERKEKKKEEKRREDKKRK 195
+ R +E K + +E R D+ R+
Sbjct: 543 QSRSRECDITKGKHSYNSRTRERSRSRDRSRR 574
Score = 69.3 bits (168), Expect = 2e-12
Identities = 45/164 (27%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Query: 2 ERQRERKRETDRGKETE-RERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
+R R R +E R +E E R R R R RE +T R R +DR R R E+E + +
Sbjct: 581 DRDRSRSKEYHRYREQEYRRRGRSRSRERRTP-PGRSRSKDRRRRRRDSRSSEREESQSR 639
Query: 61 ERDRQRQRERETERETERQRERQRQRERKR-----QTDRERDKDRDRERKRETDRNRERN 115
+D+ R +E ++ E +R + R RE+ DRD+ + ++ + N
Sbjct: 640 NKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDN 699
Query: 116 R-KGGRERDKQTERERDR-ERERQRQRERERQRQRERKRETDRE 157
K ++K+ E+ R E+E Q+ + +E E+ ++ D E
Sbjct: 700 ELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHE 743
Score = 67.8 bits (164), Expect = 6e-12
Identities = 50/208 (24%), Positives = 94/208 (45%), Gaps = 18/208 (8%)
Query: 3 RQRERKRETDRGKETERERDRQRE-------RENQTERENRHRQRDRHRERDRQTDREKE 55
+ RER+RE + + QR R+ + R+R R R RDR E
Sbjct: 300 KNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETP 359
Query: 56 RERQKERDR-QRQRERETER-------ETERQRERQRQ--RERKRQTDRERDKDRDRERK 105
++E R QR R ER E +E QR R ++R+ R+ RK
Sbjct: 360 PHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRK 419
Query: 106 RETDRNRERNRKGGRERDKQTERERD-RERERQRQRERERQRQRERKRETDRERQRWAER 164
E ++ + ++ +ERD + E+D + + + ++R + + R + +++ +ER R
Sbjct: 420 NEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNR 479
Query: 165 EERKKERKKERKKERKEKKKEEKRREDK 192
E K+ R + + ++ + K++EK+ + K
Sbjct: 480 NEEKRMRSRSKGRDHENVKEKEKQSDSK 507
Score = 62.4 bits (150), Expect = 3e-10
Identities = 51/203 (25%), Positives = 93/203 (45%), Gaps = 13/203 (6%)
Query: 5 RERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTD-REKERERQKERD 63
R+ + D + RER+R+RE + +++R R+ R R R R
Sbjct: 288 RKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRS 347
Query: 64 RQRQRERETERETERQRERQR-QRERKRQTDRERDKDRD-----RERKRETDRNRER--- 114
R R R R +E ++E QR QR R +R D+ +E +R R +ER
Sbjct: 348 RSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKIT 407
Query: 115 -NRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKK 173
+R +++ E+E+ + + +ER+ +R E+ + + ++ A+ + R K ++K
Sbjct: 408 DHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEK 467
Query: 174 ERKKER--KEKKKEEKRREDKKR 194
+ KER K + EEKR + +
Sbjct: 468 SKSKERDSKHNRNEEKRMRSRSK 490
Score = 54.7 bits (130), Expect = 5e-08
Identities = 48/236 (20%), Positives = 99/236 (41%), Gaps = 53/236 (22%)
Query: 10 ETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRE 69
++D +++ D + E+ TE +++ R++ +HR+ R+ +EK++ ++ ++ + E
Sbjct: 203 DSDSSSDSQSSSDSS-DSESATEEKSKKRKK-KHRKNSRKHKKEKKKRKKSKKSASSESE 260
Query: 70 ---------------------------RETERETERQRERQRQRERKRQTDRERDKDRDR 102
R++ + + + + R+RER+R+ + +
Sbjct: 261 AENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASY 320
Query: 103 ERKRETDRNRERNRKGGRERDKQTERERDRERERQ-------RQRERERQRQR----ERK 151
+R+ R+ + + G R + R R R+R R+ RQ + QR R ER
Sbjct: 321 QRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERW 380
Query: 152 RETDRERQRWAEREERKKERKKERK-------------KERKEKKKEEKRREDKKR 194
+ D+ + +R R KERK K KEKK ++ + K+R
Sbjct: 381 IKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKER 436
Score = 44.3 bits (103), Expect = 7e-05
Identities = 25/135 (18%), Positives = 64/135 (47%), Gaps = 12/135 (8%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQT--ERENRHRQRDRHRERDRQTDREKERERQK 60
R+R R ++R + R +D+ R +E+++ +EN ++ + + RE++
Sbjct: 623 RRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKA 682
Query: 61 ERDRQ-----RQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERN 115
+RD+ +Q ++ E ++ + ++ ++ R +K+ + + +E D E+N
Sbjct: 683 DRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRS-----SVEKENQKSKGQENDHVHEKN 737
Query: 116 RKGGRERDKQTERER 130
+K E T+ ++
Sbjct: 738 KKFDHESSPGTDEDK 752
Score = 43.9 bits (102), Expect = 9e-05
Identities = 20/74 (27%), Positives = 37/74 (50%)
Query: 120 RERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKER 179
+ + K+ E++R + + + + +D A E+ KK +KK RK R
Sbjct: 180 KSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSR 239
Query: 180 KEKKKEEKRREDKK 193
K KK+++KR++ KK
Sbjct: 240 KHKKEKKKRKKSKK 253
Score = 43.9 bits (102), Expect = 9e-05
Identities = 35/150 (23%), Positives = 69/150 (46%), Gaps = 40/150 (26%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERE-NRHRQRDRHRERDRQTDREKE------ 55
R R R+R T G+ ++R R+R +ERE ++ R +D++R ++ ++ KE
Sbjct: 603 RSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEK 662
Query: 56 ---------------RERQKERDRQ-----RQRERETE--------RETERQR---ERQR 84
RE++ +RD+ +Q ++ E +E E+ R E++
Sbjct: 663 RMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKEN 722
Query: 85 QRERKRQTDR--ERDKDRDRERKRETDRNR 112
Q+ + ++ D E++K D E TD ++
Sbjct: 723 QKSKGQENDHVHEKNKKFDHESSPGTDEDK 752
Score = 33.9 bits (76), Expect = 0.097
Identities = 18/103 (17%), Positives = 42/103 (40%), Gaps = 3/103 (2%)
Query: 100 RDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQ 159
+ + +K E R++ + D + + + ++ ++RK+ + R+
Sbjct: 180 KSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKK---KHRK 236
Query: 160 RWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGEGISP 202
+ ++ KK+RKK +K E + E + + E I P
Sbjct: 237 NSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPP 279
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 97.8 bits (242), Expect = 5e-21
Identities = 65/213 (30%), Positives = 121/213 (56%), Gaps = 20/213 (9%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTER--ENRHRQRDRHRERDRQTDREKER--E 57
+R RE+++E ++ RE+ RE+E Q + E Q ++ RE++ + R++ER E
Sbjct: 321 KRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWE 380
Query: 58 RQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDR-ERKRETDRNRERNR 116
++K+ Q Q+ R+ E Q ER R++E + RE++K ++ E+ RE + +E+ +
Sbjct: 381 QEKQMREQEQKMRDQEERMWEQDERLREKEERM---REQEKMWEQVEKMREEKKMQEQEK 437
Query: 117 KGGRERDKQTERERDRERERQRQRERERQRQRERK-----------RETDRERQRWAERE 165
K + +K E ER RERE++ + E E R++E K E + ++QR E++
Sbjct: 438 KTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQK 497
Query: 166 ERKKERKKERKKERKEKKKEEKRREDKKRKWGE 198
E+ E++K +++E K ++EEK R D++ WG+
Sbjct: 498 EKLWEQEKMQEQEEKIWEQEEKIR-DQEEMWGQ 529
Score = 95.1 bits (235), Expect = 4e-20
Identities = 58/211 (27%), Positives = 116/211 (54%), Gaps = 16/211 (7%)
Query: 1 MERQRERKRETD-RGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQ 59
M RQ ER RE + + +E E + RQ +R + E+E R ++++ +++ + E+ +E++
Sbjct: 295 MWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQE 354
Query: 60 KERDRQRQRERETERETERQRER-------QRQRERKRQTDRERDKDRDRERKRETDRNR 112
++ Q ++ RE E + RQ ER R++E+K + ER ++D + + +R R
Sbjct: 355 EKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMR 414
Query: 113 ERNR-----KGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREER 167
E+ + + RE K E+E+ + ++ +E ER R+RE+K + E R +E
Sbjct: 415 EQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMR---EQEE 471
Query: 168 KKERKKERKKERKEKKKEEKRREDKKRKWGE 198
K ++++E E++EK+ +++R ++K K E
Sbjct: 472 KMQKQEENMWEQEEKEWQQQRLPEQKEKLWE 502
Score = 94.4 bits (233), Expect = 6e-20
Identities = 56/217 (25%), Positives = 123/217 (56%), Gaps = 22/217 (10%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
ER RE+++ ++ ++ E+ Q + + ++E + ++ +R RER+++ E+E R++E
Sbjct: 411 ERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQE 470
Query: 62 RDRQRQRE---RETERETERQR---------ERQRQRERKRQTDRERDKDRDRERKRETD 109
Q+Q E + E+E ++QR E+++ +E++ + + +K RD+E +
Sbjct: 471 EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQE 530
Query: 110 RNRERNRKGGRERD---KQTERERDRERERQRQRERERQRQRERKRET------DRERQR 160
+ R K + D +Q E+ RD+E++ Q ER ++ +E++++T RE +R
Sbjct: 531 KKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEER 590
Query: 161 WAEREER-KKERKKERKKERKEKKKEEKRREDKKRKW 196
ERE++ ++E + R++E K +++EEK +E +++ W
Sbjct: 591 MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMW 627
Score = 93.6 bits (231), Expect = 1e-19
Identities = 54/203 (26%), Positives = 114/203 (56%), Gaps = 8/203 (3%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQT-ERENRHRQRDRHRERDRQTDREKERERQK 60
+ ++ R +E + ER + +E+E +T ++E + R+ +R RER+++ E+E R++
Sbjct: 549 QEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ 608
Query: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
E Q Q E+ E+E + + ++ +E++ + + +K ++E K + ++
Sbjct: 609 EEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLW 668
Query: 121 ERDKQTERERDRERERQ--RQRERERQRQRERKRETDRERQRWAE--REERKKERKKE-- 174
E +K E+E+ +E+E + Q + E++ Q + K+ D+E+ R E RE KK R++E
Sbjct: 669 EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEM 728
Query: 175 -RKKERKEKKKEEKRREDKKRKW 196
R++E K +++EEK +E ++ W
Sbjct: 729 MREQEEKMQEQEEKMQEQEEEMW 751
Score = 93.2 bits (230), Expect = 1e-19
Identities = 54/212 (25%), Positives = 118/212 (55%), Gaps = 17/212 (8%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
M Q ER E D + + +R RE+E E+ + R+ + +E++++T ++E+ +++
Sbjct: 392 MRDQEERMWEQD--ERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEE 449
Query: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
ER R+R+++ E ET R++E + Q++ + ++E +K+ ++R E K
Sbjct: 450 ERIREREKKMREEEETMREQEEKMQKQEENMWEQE-EKEWQQQRLPEQKEKLWEQEKMQE 508
Query: 121 ERDK---QTERERDRER---------ERQRQRERERQRQRERKRETDRERQRWAEREERK 168
+ +K Q E+ RD+E +++ RE+E Q + ++ D+E++ W + E +
Sbjct: 509 QEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERME 568
Query: 169 KERKKERKK--ERKEKKKEEKRREDKKRKWGE 198
K+ +++ KK +++EK +EE+R ++++K E
Sbjct: 569 KKTQEQEKKTWDQEEKMREEERMREREKKMRE 600
Score = 92.8 bits (229), Expect = 2e-19
Identities = 52/200 (26%), Positives = 116/200 (58%), Gaps = 6/200 (3%)
Query: 3 RQRERK-RETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQT-DREKERERQK 60
R++E+K R+ + + ER R++E + + + E RQ R RE++++ ++EKE QK
Sbjct: 282 REQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQK 341
Query: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
E Q ++ +E E + Q E+ R++E K ER +++++ + + + R++ +
Sbjct: 342 ELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWE 401
Query: 121 ERDKQTERE-RDRERER---QRQRERERQRQRERKRETDRERQRWAEREERKKERKKERK 176
+ ++ E+E R RE+E+ Q ++ RE ++ +E++++T + ++ E E ++ KK R+
Sbjct: 402 QDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMRE 461
Query: 177 KERKEKKKEEKRREDKKRKW 196
+E +++EEK ++ ++ W
Sbjct: 462 EEETMREQEEKMQKQEENMW 481
Score = 91.7 bits (226), Expect = 4e-19
Identities = 58/208 (27%), Positives = 121/208 (58%), Gaps = 15/208 (7%)
Query: 2 ERQRERKRETDRGKETERERDR--QRERENQTERENRHRQRDRHRE-RDRQTDREKERER 58
ER RER+++ +ET RE++ Q++ EN E+E + Q+ R E +++ ++EK +E+
Sbjct: 450 ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 509
Query: 59 QKERDRQRQRERETERETERQRERQRQRERKRQTDR---ERDKDRDRERKRETDRNRERN 115
+++ Q ++ R+ E ++++ RQ + + Q D+ + +K RD+E+K ER
Sbjct: 510 EEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE--ERM 567
Query: 116 RKGGRERDKQT------ERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERK- 168
K +E++K+T RE +R RER+++ E + RE++ + + ++ E+EE+
Sbjct: 568 EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMW 627
Query: 169 KERKKERKKERKEKKKEEKRREDKKRKW 196
++ +K +++E K ++EEK E +++ W
Sbjct: 628 EQEEKMQEQEEKMWEQEEKMWEQEEKMW 655
Score = 90.1 bits (222), Expect = 1e-18
Identities = 48/178 (26%), Positives = 111/178 (62%), Gaps = 5/178 (2%)
Query: 18 ERERDRQRERENQTERENRHRQRDRHRERD-RQTDREKERERQKERDRQRQRE-RETERE 75
+ E R++E++ + + E RQ +R RE++ + ++E++ RQ++R R++++E RE E+E
Sbjct: 277 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKE 336
Query: 76 TERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERE 135
Q+E + Q E+ ++ + + + ++ R++E R+ R +E+ + + ++ R++E
Sbjct: 337 LREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE 396
Query: 136 RQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKK 193
+ + ER R++E E RE+++ E+ E+ +E KK +++E+K + +EEK +E+++
Sbjct: 397 ERMWEQDERLREKE---ERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEER 451
Score = 89.7 bits (221), Expect = 1e-18
Identities = 50/205 (24%), Positives = 116/205 (56%), Gaps = 12/205 (5%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRD---RHRERDRQTDREKERER 58
+ +R K+ ++ K+T + ++ RE E ERE + R+ + R +E Q EK +E+
Sbjct: 563 QEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQ 622
Query: 59 QKERDRQRQRERETERETERQRERQRQRERK----RQTDRERDKDRDRERKRETDRNRER 114
+++ Q ++ +E E + Q E+ ++E K ++ +++K + E+ +E ++ +E+
Sbjct: 623 EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQ 682
Query: 115 NRK--GGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERK 172
K + +K+T+ + + ++++ RE E R+RE+K + E R E+EE+ +E++
Sbjct: 683 EEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMR--EQEEKMQEQE 740
Query: 173 KERKKERKEK-KKEEKRREDKKRKW 196
++ +++ +E ++EEK E +++ W
Sbjct: 741 EKMQEQEEEMWEQEEKMWEQEEKMW 765
Score = 89.4 bits (220), Expect = 2e-18
Identities = 48/207 (23%), Positives = 111/207 (53%), Gaps = 15/207 (7%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKER------ 56
R+ ER RE ++ E E R++E + Q + E Q ++ E++ + ++E+
Sbjct: 586 REEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEE 645
Query: 57 ----ERQKERDRQR---QRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETD 109
+ +K ++QR Q+E+ E E +++E+ +++E K + +K + K+ D
Sbjct: 646 KMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWD 705
Query: 110 RNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKK 169
+ + R + RER+K+ E + RE++ + + + ++ +E++ E + ++ E+EE+
Sbjct: 706 QEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMW 765
Query: 170 ERKKERKKERKEKKKEEKRREDKKRKW 196
E ++R E+KEK E ++ +++++ W
Sbjct: 766 E--QQRLPEQKEKLWEHEKMQEQEKIW 790
Score = 89.0 bits (219), Expect = 3e-18
Identities = 56/228 (24%), Positives = 120/228 (52%), Gaps = 34/228 (14%)
Query: 1 MERQRERKRETDRGKET--------ERERDRQRERENQTERENRHRQRDRHRERDRQTDR 52
+E+ RE K+ ++ K+T E ER R+RE++ + E E Q ++ ++++
Sbjct: 423 VEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE 482
Query: 53 EKERE-------RQKERDRQRQRERETERETERQRER-----------------QRQRER 88
++E+E QKE+ ++++ +E E + Q E+ ++ RE+
Sbjct: 483 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 542
Query: 89 KRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQR 148
+ Q + +K RD+E+K ER K +E++K+T + ++ RE +R RERE++ +
Sbjct: 543 EDQMWEQEEKMRDQEQKMWD--QEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 600
Query: 149 ERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKW 196
E + ++E + + E+ +++ +K ++E K +++EEK E +++ W
Sbjct: 601 EEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMW 648
Score = 89.0 bits (219), Expect = 3e-18
Identities = 47/197 (23%), Positives = 117/197 (59%), Gaps = 9/197 (4%)
Query: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
+++ R++E ++ E+ RD++++ +Q ER + Q E++++T ++E+ R++ER
Sbjct: 536 QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQ-----EQEKKTWDQEEKMREEER 590
Query: 63 DRQRQRE-RETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
R+R+++ RE E Q E+ +++E K Q E+ +++ + + + ++ E+ K +
Sbjct: 591 MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 650
Query: 122 RDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKE 181
+K E++R E Q+++ E ++ +E+++ ++E + W + + KK +++E+K +E
Sbjct: 651 EEKMWEQQRLPE---QKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQE 707
Query: 182 KKKEEKRREDKKRKWGE 198
K +EE+ ++++K E
Sbjct: 708 KMREEESMREREKKMRE 724
Score = 88.6 bits (218), Expect = 3e-18
Identities = 58/214 (27%), Positives = 119/214 (55%), Gaps = 21/214 (9%)
Query: 5 RERKRETDRGK---------ETERERDRQRERENQTERENRHRQRDRHRERDRQTDRE-K 54
+E KR+ +R K + E RQ E + E++ R ++ R+ +R ++E K
Sbjct: 249 KELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGK 308
Query: 55 ERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRER 114
RE++++ RQ +R RE E+E Q + R+++ R+ + + + ++ ++E ++ RE+
Sbjct: 309 MREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQE-EKMREQ 367
Query: 115 NRKGGRERDKQTERERDRERERQRQRERERQ--RQRERKRETD---RERQRWAEREERKK 169
K R+ ++ E+E+ + Q+ R++E + Q ER RE + RE+++ E+ E+ +
Sbjct: 368 EEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMR 427
Query: 170 ERKKERKKERK-----EKKKEEKRREDKKRKWGE 198
E KK +++E+K EK +EE+R ++++K E
Sbjct: 428 EEKKMQEQEKKTRDQEEKMQEEERIREREKKMRE 461
Score = 87.0 bits (214), Expect = 1e-17
Identities = 44/202 (21%), Positives = 109/202 (53%), Gaps = 4/202 (1%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
M Q E+ +E + + + E+ ++E + Q + E Q ++ E++ + ++ QK
Sbjct: 605 MREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQK 664
Query: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
E+ + ++ +E E+ E++ + Q + +++T + K D+E+ RE + RER +K
Sbjct: 665 EKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMRE 724
Query: 121 ERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAERE--ERKKERKKERKKE 178
E + E+E + + ++ +E+E + + ++ ++E + W ++ E+K++ + K +
Sbjct: 725 EEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQ 784
Query: 179 RKEK--KKEEKRREDKKRKWGE 198
+EK ++EEK R+ +++ G+
Sbjct: 785 EQEKIWEQEEKMRDQEEKMRGQ 806
Score = 84.7 bits (208), Expect = 5e-17
Identities = 51/211 (24%), Positives = 116/211 (54%), Gaps = 17/211 (8%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
M Q E+ RE + + ER ++E++ + + + Q +R E+D + ++ER R++
Sbjct: 357 MWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQ 416
Query: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
E+ ++ + E++ + Q ++ R +E K Q + ER ++R+++ + E + RE+ K +
Sbjct: 417 EKMWEQVEKMREEKKMQEQEKKTRDQEEKMQ-EEERIREREKKMREEEETMREQEEKMQK 475
Query: 121 ERDKQTERERDRERERQRQR---------ERERQRQRERK----RETDRERQRWAEREER 167
+ + E+E E+E Q+QR E+E+ +++E K E R+++ +E++
Sbjct: 476 QEENMWEQE---EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKK 532
Query: 168 KKERKKERKKERKEKKKEEKRREDKKRKWGE 198
++K R++E + ++EEK R+ +++ W +
Sbjct: 533 MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 563
Score = 84.7 bits (208), Expect = 5e-17
Identities = 53/221 (23%), Positives = 122/221 (55%), Gaps = 25/221 (11%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHR---QRDRHRERDRQTDREKER-- 56
E+ RE++ + R +E E+++Q + Q R+ R Q +R RE++ + RE+E+
Sbjct: 362 EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM-REQEKMW 420
Query: 57 ---ERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERK--RETDRN 111
E+ +E + +++E++T + E+ +E +R RER+++ E + R++E K ++ +
Sbjct: 421 EQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 480
Query: 112 RERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETD----RERQRWAER--- 164
E+ K +++ ++E+ E+E+ +++E + Q E+ R+ + +E++ W +
Sbjct: 481 WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR 540
Query: 165 -------EERKKERKKERKKERKEKKKEEKRREDKKRKWGE 198
E+ +K R +E+K +E++ E+K +E +K+ W +
Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQ 581
Score = 84.3 bits (207), Expect = 6e-17
Identities = 42/200 (21%), Positives = 108/200 (54%), Gaps = 5/200 (2%)
Query: 4 QRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERD 63
++E K + K E+E + E E++ Q+++ E ++ ++EK +E++++
Sbjct: 628 EQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIW 687
Query: 64 RQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERD 123
Q + E++T+ + ++ ++++ RE + +RE+ + E RE + + + +E++
Sbjct: 688 EQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQE 747
Query: 124 ----KQTERERDRERERQRQRERERQRQRERKRETDRERQR-WAEREERKKERKKERKKE 178
+Q E+ ++E + Q+ Q+++ + E +E+++ W + E+ + + +K R +E
Sbjct: 748 EEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQE 807
Query: 179 RKEKKKEEKRREDKKRKWGE 198
K + +EEK R +++ WG+
Sbjct: 808 EKMRGQEEKMRGQEEKMWGQ 827
Score = 83.2 bits (204), Expect = 1e-16
Identities = 47/202 (23%), Positives = 107/202 (52%), Gaps = 5/202 (2%)
Query: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
M+ Q + + + ++ E E+ + +E+E +T + + R+ + RER+++ E+E R++
Sbjct: 673 MQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQ 732
Query: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
E Q Q E+ E+E E + ++ E++ + ++ +E+ E ++ +E+ + +
Sbjct: 733 EEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQ 792
Query: 121 ERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKK----ERK 176
E + + E+ R +E + + + E+ R +E K +E + W + E+ + +K E K
Sbjct: 793 EEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKM-WGQEEKMWGQEEKMWGQEEKMWGQEEK 851
Query: 177 KERKEKKKEEKRREDKKRKWGE 198
E K + +EEK RE +++ G+
Sbjct: 852 MEEKMQGQEEKMREQEEKMRGQ 873
Score = 81.3 bits (199), Expect = 5e-16
Identities = 45/216 (20%), Positives = 124/216 (57%), Gaps = 20/216 (9%)
Query: 1 MERQRERKRETDRGKETER----ERDRQRERENQTERENRHRQRDRHRERDRQTDREKER 56
+ Q+E+ E ++ +E E + ++ R++E +E + ++++ RE++ Q ++E+
Sbjct: 493 LPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 552
Query: 57 ERQKER---DRQRQRERETERETE---------RQRERQRQRERKRQTDRERDKDRDRER 104
R +E+ D++ + E++T+ + + R+ ER R+RE+K + + E ++++ +
Sbjct: 553 MRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKM 612
Query: 105 KRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAER 164
+ + ++ +E+ K + +K E+E + ++ E+E ++ E++R +++ + W E
Sbjct: 613 QEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE-EKMWEQQRLPEQKEKLW-EH 670
Query: 165 EERKKERKKERKKER--KEKKKEEKRREDKKRKWGE 198
E+ +++ K + ++E+ +++K E+K +E +K+ W +
Sbjct: 671 EKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQ 706
Score = 77.8 bits (190), Expect = 6e-15
Identities = 50/203 (24%), Positives = 116/203 (57%), Gaps = 9/203 (4%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDR-HRERDRQTDREKERERQK 60
E+++ K+ ++ K+T ++++ RE E+ ERE + R+ + RE++ + ++E+ +++
Sbjct: 688 EQEKMEKKTQEQEKKTW-DQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQ 746
Query: 61 ERDRQRQRERETERETERQRERQRQRERKRQT-DRERDKDRDRERKRETDRNRERNRKGG 119
E + Q E+ E+E E+ E+QR E+K + + E+ +++++ ++E + + G
Sbjct: 747 EEEMWEQEEKMWEQE-EKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRG 805
Query: 120 RERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAERE--ERKKERKKERKK 177
+E + + E+ R +E + + E+ +E K +E + W + E E K + ++E+ +
Sbjct: 806 QEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKM-WGQEEKMWGQEEKMEEKMQGQEEKMR 864
Query: 178 ERKEKKK--EEKRREDKKRKWGE 198
E++EK + EEK RE +++ G+
Sbjct: 865 EQEEKMRGQEEKMREQEEKMRGQ 887
Score = 74.7 bits (182), Expect = 5e-14
Identities = 46/200 (23%), Positives = 110/200 (55%), Gaps = 6/200 (3%)
Query: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREK-ERERQK 60
E+ E++R ++ KE E ++ +E+E E+E + ++++ ++ ++ +++ ++E+ +
Sbjct: 652 EKMWEQQRLPEQ-KEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMR 710
Query: 61 ERDRQRQRERETERETE--RQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKG 118
E + R+RE++ E E R++E + Q + ++ ++E + E+ E + ++
Sbjct: 711 EEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRL 770
Query: 119 GRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKE 178
+++K E E+ +E+E+ ++E E+ R +E K E+ R E + R +E K ++E
Sbjct: 771 PEQKEKLWEHEKMQEQEKIWEQE-EKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEE 829
Query: 179 RKEKKKEEKRREDKKRKWGE 198
K +EEK +++ WG+
Sbjct: 830 -KMWGQEEKMWGQEEKMWGQ 848
Score = 74.3 bits (181), Expect = 6e-14
Identities = 48/205 (23%), Positives = 105/205 (51%), Gaps = 9/205 (4%)
Query: 4 QRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERD 63
Q + K+ D+ K E E R+RE++ + E E Q ++ +E++ + ++E ++E
Sbjct: 697 QEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEK 756
Query: 64 RQRQRERETERET-ERQRERQRQRERKRQTDR---ERDKDRDRERKRETDRNRERNRKGG 119
Q E+ E++ Q+E+ + E+ ++ ++ + +K RD+E K R +E +G
Sbjct: 757 MWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKM---RGQEEKMRGQ 813
Query: 120 RERDKQTERERDRERERQRQRERERQRQRERK--RETDRERQRWAEREERKKERKKERKK 177
E+ + E + + E+ +E + Q E+ +E E + + E+ +++ +K R +
Sbjct: 814 EEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQ 873
Query: 178 ERKEKKKEEKRREDKKRKWGEGISP 202
E K +++EEK R +++ + G P
Sbjct: 874 EEKMREQEEKMRGQEEKIYCVGSPP 898
Score = 70.1 bits (170), Expect = 1e-12
Identities = 54/201 (26%), Positives = 104/201 (51%), Gaps = 19/201 (9%)
Query: 6 ERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREK-------ERER 58
E R T +E +++ +E+ E E Q + +E R+ +R K
Sbjct: 212 ELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNV-KELKRKLERAKFLLPQVQTNTL 270
Query: 59 QKERDRQRQRERETERETERQRERQ-RQRERKRQTD---RERDKDRDRERKRETDRNRER 114
Q+E RQ + RE E++ +Q E+ RQ ER R+ + RE+++ R+ KR ++ +E
Sbjct: 271 QEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKEL 330
Query: 115 NRKGGRERDKQTERERD-RERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKK 173
RE++K+ +++ RE+E Q Q + E+ ++E K ++E + W + E ++ K+
Sbjct: 331 -----REQEKELREQKELREQEEQMQEQEEKMWEQEEKMR-EQEEKMWRQEERLWEQEKQ 384
Query: 174 ERKKERKEKKKEEKRREDKKR 194
R++E+K + +EE+ E +R
Sbjct: 385 MREQEQKMRDQEERMWEQDER 405
Score = 56.2 bits (134), Expect = 2e-08
Identities = 49/209 (23%), Positives = 98/209 (46%), Gaps = 23/209 (11%)
Query: 2 ERQRERKRETDRGKETERE-RDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
E QR + R K+ +R + +ER+ + R+ + ++ +EK +
Sbjct: 180 ELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAES 239
Query: 61 ERDRQRQRERETERETER-------------QRERQRQRERKRQTDRERDKDRDRERKRE 107
E+ + +E +R+ ER Q E RQ E R+ ++ K R +E K
Sbjct: 240 EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEK---KIRKQEEKMW 296
Query: 108 TDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREER 167
R R ++G K E+E R+ +R RE+E++ RE+++E +++ + E+
Sbjct: 297 RQEERLREQEG-----KMREQEEKMWRQEKRLREQEKEL-REQEKELREQKELREQEEQM 350
Query: 168 KKERKKERKKERKEKKKEEKRREDKKRKW 196
+++ +K ++E K +++EEK ++R W
Sbjct: 351 QEQEEKMWEQEEKMREQEEKMWRQEERLW 379
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 96.7 bits (239), Expect = 1e-20
Identities = 65/178 (36%), Positives = 102/178 (57%), Gaps = 22/178 (12%)
Query: 30 QTERENRHRQRDRHRERDRQTD-----REKERERQKERDRQRQRERETERETERQRERQR 84
+ ER R Q + R + +T+ RE+ERER++E RQRERE ERE +R+RER R
Sbjct: 375 EIERFWRGGQYENFRVQYTETEPYHNYRERERERERE---NRQRERERERERDRERER-R 430
Query: 85 QRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERER 144
QRER+R+ + ERDK+R R RK E +R R + RD++ + RDR+RE++R++E+ +
Sbjct: 431 QREREREREHERDKERQR-RKEEWERERAK-------RDEKDRQHRDRDREKEREKEKGK 482
Query: 145 QRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGEGISP 202
+ R + + R AE +++ + K E K +R + K+K G +SP
Sbjct: 483 PKPR-----SPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSP 535
Score = 86.3 bits (212), Expect = 2e-17
Identities = 50/147 (34%), Positives = 88/147 (59%), Gaps = 8/147 (5%)
Query: 10 ETDRGKETERER-DRQRERENQTERENRHRQRDRHRERDRQTDR---EKERERQKERDRQ 65
E R + TE E RERE + ERENR R+R+R RERDR+ +R E+ERER+ ERD++
Sbjct: 386 ENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERERRQREREREREHERDKE 445
Query: 66 RQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQ 125
RQR +E E ER+R ++ +++R+ + DR+R+K+R++E+ + R+ + + K+
Sbjct: 446 RQRRKE---EWERERAKRDEKDRQHR-DRDREKEREKEKGKPKPRSPQPPSRQAEPPKKE 501
Query: 126 TERERDRERERQRQRERERQRQRERKR 152
+ + ++ R+ + +K+
Sbjct: 502 AATTGPQVKRADEWKDPWRRSKSPKKK 528
Score = 81.6 bits (200), Expect = 4e-16
Identities = 54/162 (33%), Positives = 83/162 (51%), Gaps = 12/162 (7%)
Query: 19 RERDRQRERENQTERENRHRQRDRHRER-DRQTDREKERERQKERDRQRQRERETERETE 77
RER+R+REREN+ R R+RDR RER R+ +RE+E ER KER R R+ E ERE
Sbjct: 402 RERERERERENRQRERERERERDRERERRQREREREREHERDKERQR---RKEEWERERA 458
Query: 78 RQRERQRQ-RERKRQTDRERDKDRDRERK-RETDRNRERNRKGGRERDKQTERERDRERE 135
++ E+ RQ R+R R+ +RE++K + + R + R E +K Q +R + +
Sbjct: 459 KRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDP 518
Query: 136 RQRQRERERQ------RQRERKRETDRERQRWAEREERKKER 171
+R + +++ R R+R A R R
Sbjct: 519 WRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSR 560
Score = 70.9 bits (172), Expect = 7e-13
Identities = 57/170 (33%), Positives = 85/170 (50%), Gaps = 10/170 (5%)
Query: 28 ENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRE 87
E+ ER RH +E ++ KE+E E R E ERE +++ E R
Sbjct: 298 ESAWERGLRHA-----KEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWN 352
Query: 88 RKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQ-- 145
+ D RD + D ER +GG+ + + + R+RERER+
Sbjct: 353 SRIPRD-VRDTVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERE 411
Query: 146 -RQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKR 194
RQRER+RE +R+R+R + ER++ER+ ER KER +++KEE RE KR
Sbjct: 412 NRQRERERERERDRERERRQREREREREHERDKER-QRRKEEWERERAKR 460
Score = 57.4 bits (137), Expect = 8e-09
Identities = 38/117 (32%), Positives = 62/117 (52%), Gaps = 6/117 (5%)
Query: 3 RQRERKRETDRGKETERERDRQREREN-QTERENRHRQRDRHRERDRQTDREKERERQKE 61
RQRER+RE +E ER+++RQR +E + ER R + +HR+RDR+ +REKE+ + K
Sbjct: 430 RQRERERE----REHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKP 485
Query: 62 RDRQ-RQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRK 117
R Q R+ E ++ Q +R + + R K ++ +R R R+
Sbjct: 486 RSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRR 542
Score = 37.4 bits (85), Expect = 0.009
Identities = 39/191 (20%), Positives = 68/191 (35%), Gaps = 12/191 (6%)
Query: 12 DRGKETERERDRQRERENQTERENRHRQRDRHRERD------RQTDREKERER-----QK 60
D + ER+ + E + RD ++D R +D E E Q+
Sbjct: 2 DVAESPERDPHSPEDEEQPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQE 61
Query: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
E D E + ++ + + T +++ D + T R+ R
Sbjct: 62 EEDNHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVTR 121
Query: 121 ERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERK 180
E D+ E + D E + + + E D E+ REE K + +KE
Sbjct: 122 ELDEH-ELDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESL 180
Query: 181 EKKKEEKRRED 191
E KE+K+ +D
Sbjct: 181 EAAKEKKKEDD 191
Score = 35.8 bits (81), Expect = 0.025
Identities = 36/176 (20%), Positives = 68/176 (38%), Gaps = 23/176 (13%)
Query: 2 ERQRERKRETDRGKETER-------------ERDRQ-RERENQTERENRHRQRDRHRERD 47
+R+RER+RE +R KE +R E+DRQ R+R+ + ERE +++ + + R
Sbjct: 431 QREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKERE---KEKGKPKPRS 487
Query: 48 RQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRE 107
Q R+ + + + +R E + +R + K++ R R R++
Sbjct: 488 PQ---PPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKT 544
Query: 108 TDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRET---DRERQR 160
+ + + + R R R R + + R R R
Sbjct: 545 SASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSR 600
Score = 30.0 bits (66), Expect = 1.4
Identities = 31/161 (19%), Positives = 62/161 (38%), Gaps = 7/161 (4%)
Query: 39 QRDRHRERDRQ-----TDREKERERQKERDRQRQRERETERETERQRER-QRQRERKRQT 92
+RD H D + +D + R+ ++D R ++ E E R Q E +
Sbjct: 8 ERDPHSPEDEEQPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQEEEDNHS 67
Query: 93 DRERDKDRDRERKRETDRNR-ERNRKGGRERDKQTERERDRERERQRQRERERQRQRERK 151
D E + + ++++ N R ++ E E DR + + + + E +
Sbjct: 68 DEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVTRELDEHE 127
Query: 152 RETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDK 192
+ D E ++ E +K ++ +EK + R E K
Sbjct: 128 LDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGK 168
Score = 27.3 bits (59), Expect = 9.0
Identities = 25/148 (16%), Positives = 63/148 (42%), Gaps = 3/148 (2%)
Query: 6 ERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQ 65
+ ++E + K+ + ++ +R+R++ T+ + + + + ++ Q ++
Sbjct: 751 QTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTF 810
Query: 66 RQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRK-GGRERDK 124
+E + + + R+R +D++R +R + R+RK GGR
Sbjct: 811 -VAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSP 869
Query: 125 QTERER-DRERERQRQRERERQRQRERK 151
+ ER+R + +R+RQ + K
Sbjct: 870 KPERQRGQNSKAPAAPADRKRQLSPQSK 897
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.125 0.332
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,246,971
Number of Sequences: 37866
Number of extensions: 519913
Number of successful extensions: 90563
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1774
Number of HSP's successfully gapped in prelim test: 613
Number of HSP's that attempted gapping in prelim test: 8690
Number of HSP's gapped (non-prelim): 28235
length of query: 202
length of database: 18,247,518
effective HSP length: 97
effective length of query: 105
effective length of database: 14,574,516
effective search space: 1530324180
effective search space used: 1530324180
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.