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Search of human proteins with 239747244
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239747244 PREDICTED: hypothetical protein [Homo sapiens]
(719 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239747244 PREDICTED: hypothetical protein [Homo sapiens] 1510 0.0
gi|169161033 PREDICTED: hypothetical protein [Homo sapiens] 1261 0.0
gi|239741065 PREDICTED: hypothetical protein [Homo sapiens] 1013 0.0
gi|145207958 transmembrane protein 16G isoform NGEP long [Homo s... 178 2e-44
gi|218084958 anoctamin 4 [Homo sapiens] 100 5e-21
gi|209862785 anoctamin 2 [Homo sapiens] 92 2e-18
gi|156766084 transmembrane protein 16C [Homo sapiens] 87 4e-17
gi|194306539 anoctamin 1, calcium activated chloride channel [Ho... 78 3e-14
gi|218156307 anoctamin 6 isoform c [Homo sapiens] 69 1e-11
gi|218156305 anoctamin 6 isoform c [Homo sapiens] 69 1e-11
gi|218156303 anoctamin 6 isoform b [Homo sapiens] 69 1e-11
gi|218156299 anoctamin 6 isoform a [Homo sapiens] 69 1e-11
gi|218081589 anoctamin 5 isoform b [Homo sapiens] 66 1e-10
gi|47106048 anoctamin 5 isoform a [Homo sapiens] 66 1e-10
gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens] 63 8e-10
gi|55741655 anoctamin 8 [Homo sapiens] 42 0.002
gi|94536803 transmembrane protein 16K [Homo sapiens] 38 0.037
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 37 0.064
gi|169168296 PREDICTED: hypothetical protein [Homo sapiens] 35 0.32
gi|169168044 PREDICTED: hypothetical protein [Homo sapiens] 35 0.32
gi|169167512 PREDICTED: hypothetical protein [Homo sapiens] 35 0.32
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 35 0.32
gi|32490559 low density lipoprotein receptor-related protein 10 ... 34 0.41
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] 33 0.92
gi|239755599 PREDICTED: hypothetical protein XP_002344618 [Homo ... 33 0.92
gi|239750090 PREDICTED: hypothetical protein XP_002347290 [Homo ... 33 0.92
gi|239744399 PREDICTED: hypothetical protein XP_002343154 [Homo ... 33 0.92
gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo... 32 1.6
gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo... 32 1.6
gi|12965180 taste receptor, type 2, member 10 [Homo sapiens] 32 2.1
>gi|239747244 PREDICTED: hypothetical protein [Homo sapiens]
Length = 719
Score = 1510 bits (3909), Expect = 0.0
Identities = 719/719 (100%), Positives = 719/719 (100%)
Query: 1 MTPPTGRRLCLAPCGGIYVPDSRGTFSETGKPALIKVGQSGVRPLLTVPLTPRWVRLRAR 60
MTPPTGRRLCLAPCGGIYVPDSRGTFSETGKPALIKVGQSGVRPLLTVPLTPRWVRLRAR
Sbjct: 1 MTPPTGRRLCLAPCGGIYVPDSRGTFSETGKPALIKVGQSGVRPLLTVPLTPRWVRLRAR 60
Query: 61 LGGEAATPAAAGERRLRQRRWRENFQRNLEEVSTEPAGCETRGRAQTPLASSETRTRAFS 120
LGGEAATPAAAGERRLRQRRWRENFQRNLEEVSTEPAGCETRGRAQTPLASSETRTRAFS
Sbjct: 61 LGGEAATPAAAGERRLRQRRWRENFQRNLEEVSTEPAGCETRGRAQTPLASSETRTRAFS 120
Query: 121 SSSVKWIWPPGPTPTLRARRSHGDACACATLCSSRCPAGRRIRAPSAARSRTTGTLSGQL 180
SSSVKWIWPPGPTPTLRARRSHGDACACATLCSSRCPAGRRIRAPSAARSRTTGTLSGQL
Sbjct: 121 SSSVKWIWPPGPTPTLRARRSHGDACACATLCSSRCPAGRRIRAPSAARSRTTGTLSGQL 180
Query: 181 TRGLLWQVAEILDRTISRKKKHTEMGIAHLLGLFELPGYQVPGSDLNSCQLLYPYWACWG 240
TRGLLWQVAEILDRTISRKKKHTEMGIAHLLGLFELPGYQVPGSDLNSCQLLYPYWACWG
Sbjct: 181 TRGLLWQVAEILDRTISRKKKHTEMGIAHLLGLFELPGYQVPGSDLNSCQLLYPYWACWG 240
Query: 241 YWHKYQPLDQPLDKLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQD 300
YWHKYQPLDQPLDKLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQD
Sbjct: 241 YWHKYQPLDQPLDKLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQD 300
Query: 301 QEAMPSSAPHHWDCSDFQDQEVMPSSALHHWDCSDFQDQEECPHLQFAALALQMTQNPVT 360
QEAMPSSAPHHWDCSDFQDQEVMPSSALHHWDCSDFQDQEECPHLQFAALALQMTQNPVT
Sbjct: 301 QEAMPSSAPHHWDCSDFQDQEVMPSSALHHWDCSDFQDQEECPHLQFAALALQMTQNPVT 360
Query: 361 GLKEPYFQPHSCLSHLLTSSAAILTVLCVVMIFLVSVIIYHGIISIAMFHTGNSVLMTQA 420
GLKEPYFQPHSCLSHLLTSSAAILTVLCVVMIFLVSVIIYHGIISIAMFHTGNSVLMTQA
Sbjct: 361 GLKEPYFQPHSCLSHLLTSSAAILTVLCVVMIFLVSVIIYHGIISIAMFHTGNSVLMTQA 420
Query: 421 NVLWGNGGDASMKMPSLSFSVCQFLFFSLLHGILQRQCGPGGCHIQVTQQLIIIMVGKQL 480
NVLWGNGGDASMKMPSLSFSVCQFLFFSLLHGILQRQCGPGGCHIQVTQQLIIIMVGKQL
Sbjct: 421 NVLWGNGGDASMKMPSLSFSVCQFLFFSLLHGILQRQCGPGGCHIQVTQQLIIIMVGKQL 480
Query: 481 LNHMEEFVGLGGGPGPDTPCLPELQFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFLC 540
LNHMEEFVGLGGGPGPDTPCLPELQFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFLC
Sbjct: 481 LNHMEEFVGLGGGPGPDTPCLPELQFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFLC 540
Query: 541 KYQRPMAGRGWTSGSDCSCWRPCELILPRTNARSRLGYWLNGQGQILGRRRGGNAGFGVE 600
KYQRPMAGRGWTSGSDCSCWRPCELILPRTNARSRLGYWLNGQGQILGRRRGGNAGFGVE
Sbjct: 541 KYQRPMAGRGWTSGSDCSCWRPCELILPRTNARSRLGYWLNGQGQILGRRRGGNAGFGVE 600
Query: 601 IREPLQTPQPRYKASRDVGVNLALFYWKLLAVHVHLGFIIAFENVVFFFLCPNDRLVPDV 660
IREPLQTPQPRYKASRDVGVNLALFYWKLLAVHVHLGFIIAFENVVFFFLCPNDRLVPDV
Sbjct: 601 IREPLQTPQPRYKASRDVGVNLALFYWKLLAVHVHLGFIIAFENVVFFFLCPNDRLVPDV 660
Query: 661 PALATKITARALPGQAGGGRQPGDAVSVSKAGGPRPHPQHNDHNDHAPWPALKLQLSPL 719
PALATKITARALPGQAGGGRQPGDAVSVSKAGGPRPHPQHNDHNDHAPWPALKLQLSPL
Sbjct: 661 PALATKITARALPGQAGGGRQPGDAVSVSKAGGPRPHPQHNDHNDHAPWPALKLQLSPL 719
>gi|169161033 PREDICTED: hypothetical protein [Homo sapiens]
Length = 723
Score = 1261 bits (3262), Expect = 0.0
Identities = 637/741 (85%), Positives = 643/741 (86%), Gaps = 40/741 (5%)
Query: 1 MTPPTGRRLCLAPCGGIYVPDSRGTFSETGKPALIKVGQSGVRPLLTVPLTPRWVRLRAR 60
MTPPTGRRLCLAPCGGIYVPDSRGTFSETGKPALIKVGQSGVRPLLTVPLTPRWVRLRAR
Sbjct: 1 MTPPTGRRLCLAPCGGIYVPDSRGTFSETGKPALIKVGQSGVRPLLTVPLTPRWVRLRAR 60
Query: 61 LGGEAATPAAAGERRLRQRRWRENFQRNLEEVSTEPAGCETRGRAQTPLASSETRTRAFS 120
LGGEAATPAAAGERRLRQRRWRENFQRNLEEVSTEPAGCETRGRAQTPLASSETRTRAFS
Sbjct: 61 LGGEAATPAAAGERRLRQRRWRENFQRNLEEVSTEPAGCETRGRAQTPLASSETRTRAFS 120
Query: 121 SSSVKWIWPPGPTPTLRARRSHGDACACATLCSSRCPAGRRIRAPSAARSRTTGTLSGQL 180
SSSVKWIWPPGPTPTLRARRSHGDACACATLCSSRC P+ R R S
Sbjct: 121 SSSVKWIWPPGPTPTLRARRSHGDACACATLCSSRC--------PAGRRIRAP---SAAR 169
Query: 181 TRGLLWQVAEILDRTISRKKKHTEMGIAHLLGLFELPGYQVPGSDLNSCQLLYPYWACWG 240
+R W AEI S TE + LG Y V S L +C G
Sbjct: 170 SRTNSW--AEIPMAPTSLTCGCTEWASLNCLGT----RYPVQISTLANCCTHTGLAGDTG 223
Query: 241 YWHKYQPLDQPLDKLSCLF----------------------DHPGTVFFSIFMSFWGHGL 278
Y P+ + L D GTVFFSIFMSFWGHGL
Sbjct: 224 TSF-YMACLLPVTLVGTLLFISSLVTVGTNTLVWVAVEGLGDGLGTVFFSIFMSFWGHGL 282
Query: 279 PGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHWDCSDFQDQEVMPSSALHHWDCSDFQD 338
PGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHWDCSDFQDQEVMPSSALHHWDCSDFQD
Sbjct: 283 PGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHWDCSDFQDQEVMPSSALHHWDCSDFQD 342
Query: 339 QEECPHLQFAALALQMTQNPVTGLKEPYFQPHSCLSHLLTSSAAILTVLCVVMIFLVSVI 398
QEECPHLQFAALALQMTQNPVTGLKEPYFQPHSCLSHLLTSSAAILTVLCVVMIFLVSVI
Sbjct: 343 QEECPHLQFAALALQMTQNPVTGLKEPYFQPHSCLSHLLTSSAAILTVLCVVMIFLVSVI 402
Query: 399 IYHGIISIAMFHTGNSVLMTQANVLWGNGGDASMKMPSLSFSVCQFLFFSLLHGILQRQC 458
IYHGIISIAMFHTGNSVLMTQANVLWGNGGDASMKMPSLSFSVCQFLFFSLLHGILQRQC
Sbjct: 403 IYHGIISIAMFHTGNSVLMTQANVLWGNGGDASMKMPSLSFSVCQFLFFSLLHGILQRQC 462
Query: 459 GPGGCHIQVTQQLIIIMVGKQLLNHMEEFVGLGGGPGPDTPCLPELQFGFITIFVGAFLL 518
GPGGCHIQVTQQLIIIMVGKQLLNHMEEFVGLGGGPGPDTPCLPELQFGFITIFVGAFLL
Sbjct: 463 GPGGCHIQVTQQLIIIMVGKQLLNHMEEFVGLGGGPGPDTPCLPELQFGFITIFVGAFLL 522
Query: 519 APLFTLLNNRVEIGLDAHKFLCKYQRPMAGRGWTSGSDCSCWRPCELILPRTNARSRLGY 578
APLFTLLNNRVEIGLDAHKFLCKYQRPMAGRGWTSGSDCSCWRPCELILPRTNARSRLGY
Sbjct: 523 APLFTLLNNRVEIGLDAHKFLCKYQRPMAGRGWTSGSDCSCWRPCELILPRTNARSRLGY 582
Query: 579 WLNGQGQILGRRRGGNAGFGVEIREPLQTPQPRYKASRDVGVNLALFYWKLLAVHVHLGF 638
WLNGQGQILGRRRGGNAGFGVEIREPLQTPQPRYKASRDVGVNLALFYWKLLAVHVHLGF
Sbjct: 583 WLNGQGQILGRRRGGNAGFGVEIREPLQTPQPRYKASRDVGVNLALFYWKLLAVHVHLGF 642
Query: 639 IIAFENVVFFFLCPNDRLVPDVPALATKITARALPGQAGGGRQPGDAVSVSKAGGPRPHP 698
IIAFENVVFFFLCPNDRLVPDVPALATKITARALPGQAGGGRQPGDAVSVSKAGGPRPHP
Sbjct: 643 IIAFENVVFFFLCPNDRLVPDVPALATKITARALPGQAGGGRQPGDAVSVSKAGGPRPHP 702
Query: 699 QHNDHNDHAPWPALKLQLSPL 719
QHNDHNDHAPWPALKLQLSPL
Sbjct: 703 QHNDHNDHAPWPALKLQLSPL 723
>gi|239741065 PREDICTED: hypothetical protein [Homo sapiens]
Length = 494
Score = 1013 bits (2619), Expect = 0.0
Identities = 485/515 (94%), Positives = 489/515 (94%), Gaps = 21/515 (4%)
Query: 205 MGIAHLLGLFELPGYQVPGSDLNSCQLLYPYWACWGYWHKYQPLDQPLDKLSCLFDHPGT 264
MGIAHLLGLFELPGYQVPGSDLNSCQLLYPYWACWGYWHKYQPLDQPLDKLSCLFDHPGT
Sbjct: 1 MGIAHLLGLFELPGYQVPGSDLNSCQLLYPYWACWGYWHKYQPLDQPLDKLSCLFDHPGT 60
Query: 265 VFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHWDCSDFQDQEVMP 324
VFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHWDCSDFQDQEVMP
Sbjct: 61 VFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHWDCSDFQDQEVMP 120
Query: 325 SSALHHWDCSDFQDQEECPHLQFAALALQMTQNPVTGLKEPYFQPHSCLSHLLTSSAAIL 384
SSALHHWDCSDFQDQE FAALALQMTQNPVTGLKEPYFQPHSCLSHLLTSSAAIL
Sbjct: 121 SSALHHWDCSDFQDQE------FAALALQMTQNPVTGLKEPYFQPHSCLSHLLTSSAAIL 174
Query: 385 TVLCVVMIFLVSVIIYHGIISIAMFHTGNSVLMTQANVLWGNGGDASMKMPSLSFSVCQF 444
TVLCVVMIFLVSVIIYHGIISIAMFHTGNSVLMTQANVLWGNGG + LS +C
Sbjct: 175 TVLCVVMIFLVSVIIYHGIISIAMFHTGNSVLMTQANVLWGNGGPKA-----LSKVLC-- 227
Query: 445 LFFSLLHGILQRQCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFVGLGGGPGPDTPCLPEL 504
+ Q+QCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFVGLGGGPGPDTPCLPEL
Sbjct: 228 --------VCQQQCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFVGLGGGPGPDTPCLPEL 279
Query: 505 QFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFLCKYQRPMAGRGWTSGSDCSCWRPCE 564
QFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFLCKYQRPMAGRGWTSGSDCSCWRPCE
Sbjct: 280 QFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFLCKYQRPMAGRGWTSGSDCSCWRPCE 339
Query: 565 LILPRTNARSRLGYWLNGQGQILGRRRGGNAGFGVEIREPLQTPQPRYKASRDVGVNLAL 624
LILPRTNARSRLGYWLNGQGQILGRRRGGNAGFGVEIREPLQTPQPRYKASRDVGVNLAL
Sbjct: 340 LILPRTNARSRLGYWLNGQGQILGRRRGGNAGFGVEIREPLQTPQPRYKASRDVGVNLAL 399
Query: 625 FYWKLLAVHVHLGFIIAFENVVFFFLCPNDRLVPDVPALATKITARALPGQAGGGRQPGD 684
FYWKLLAVHVHLGFIIAFENVVFFFLCPNDRLVPDVPALATKITARALPGQAGGGRQPGD
Sbjct: 400 FYWKLLAVHVHLGFIIAFENVVFFFLCPNDRLVPDVPALATKITARALPGQAGGGRQPGD 459
Query: 685 AVSVSKAGGPRPHPQHNDHNDHAPWPALKLQLSPL 719
AVSVSKAGGPRPHPQHNDHNDHAPWPALKLQLSPL
Sbjct: 460 AVSVSKAGGPRPHPQHNDHNDHAPWPALKLQLSPL 494
>gi|145207958 transmembrane protein 16G isoform NGEP long [Homo
sapiens]
Length = 933
Score = 178 bits (451), Expect = 2e-44
Identities = 155/508 (30%), Positives = 209/508 (41%), Gaps = 152/508 (29%)
Query: 258 LFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHWDCSDF 317
LFDH GTVFFS+FM+ W L + SATLA+ W
Sbjct: 417 LFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRW------------------------ 452
Query: 318 QDQEVMPSSALHHWDCSDFQDQEECPHLQFAALALQMTQNPVTGLKEPYFQPHSCLSHLL 377
DCSD++D EE P QFAA A NP+TG EPYF S +L
Sbjct: 453 --------------DCSDYEDTEERPRPQFAASAPMTAPNPITGEDEPYFPERSRARRML 498
Query: 378 TSSAAILTVLCVVMIFLVSVIIYHGIISIAMFHTGNS----------------------- 414
S I+ ++ VV++ LVS+I+Y I++I + +GN+
Sbjct: 499 AGSVVIVVMVAVVVMCLVSIILYRAIMAIVVSRSGNTLLAAWASRIASLTGSVVNLVFIL 558
Query: 415 ----VLMTQANVL--WGNGGDASMKMPSLSFSVCQFLF---------------------- 446
+ ++ A+VL W + + + V F F
Sbjct: 559 ILSKIYVSLAHVLTRWEMHRTQTKFEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPG 618
Query: 447 -FSLLHGILQRQCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFV----------------- 488
+ L G+ +C GGC I++ Q+L++IMVGKQ++N+M+E +
Sbjct: 619 NYHTLFGVRNEECAAGGCLIELAQELLVIMVGKQVINNMQEVLIPKLKGWWQKFRLRSKK 678
Query: 489 -------GLGGGPGPD----TPCLP--------ELQFGFITIFVGAFLLAPLFTLLNNRV 529
G GP D PC LQFGF+TIFV A LAPLF LLNN V
Sbjct: 679 RKAGASAGASQGPWEDDYELVPCEGLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWV 738
Query: 530 EIGLDAHKFLCKYQRPMAGRGWTSG---------------SDCSCWRPCELILPRTNARS 574
EI LDA KF+C+Y+RP+A R G S+ LPR R
Sbjct: 739 EIRLDARKFVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRAYYRW 798
Query: 575 RLGYWLNG-QGQILGRRRGGNAGFGVEIREPLQTPQPRYKASRDVGVNLALFYWKLLAVH 633
+ L G L R A RY+A RD + + YW LLA
Sbjct: 799 TRAHDLRGFLNFTLARAPSSFAA--------AHNRTCRYRAFRDDDGHYSQTYWNLLA-- 848
Query: 634 VHLGFIIAFENVVFFFLCPNDRLVPDVP 661
+ L F+I FE+VVF D LVPD+P
Sbjct: 849 IRLAFVIVFEHVVFSVGRLLDLLVPDIP 876
Score = 102 bits (253), Expect = 2e-21
Identities = 90/321 (28%), Positives = 133/321 (41%), Gaps = 75/321 (23%)
Query: 190 EILDRTISRKKKHTEMGIAHLL-------------GLFELPGYQVPGSDLNSCQLLYPYW 236
EIL +T +K +GI LL G F+ P LN Q+L+ +W
Sbjct: 261 EILAKTPYGHEKKNLLGIHQLLAEGVLSAAFPLHDGPFKTPPEGPQAPRLNQRQVLFQHW 320
Query: 237 ACWGYWHKYQPLDQPLDKLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDC- 295
A WG W+KYQPLD + F ++F+ + G LP A+ TL C
Sbjct: 321 ARWGKWNKYQPLDH----VRRYFGEKVALYFAWLGFYTGWLLPAAV---VGTLVFLVGCF 373
Query: 296 ---SDFQDQEAMPSS-----APHHWDCSDF------------------------------ 317
SD QE S P DC +
Sbjct: 374 LVFSDIPTQELCGSKDSFEMCPLCLDCPFWLLSSACALAQAGRLFDHGGTVFFSLFMALW 433
Query: 318 -----QDQEVMPSSALHHWDCSDFQDQEECPHLQFAALALQMTQNPVTGLKEPYFQPHSC 372
+ + ++ + WDCSD++D EE P QFAA A NP+TG EPYF S
Sbjct: 434 AVLLLEYWKRKSATLAYRWDCSDYEDTEERPRPQFAASAPMTAPNPITGEDEPYFPERSR 493
Query: 373 LSHLLTSSAAILTVLCVVMIFLVSVIIYHGIISIAMFHTGNSVLMTQANVLWGNGGDASM 432
+L S I+ ++ VV++ LVS+I+Y I++I + +GN++L A+
Sbjct: 494 ARRMLAGSVVIVVMVAVVVMCLVSIILYRAIMAIVVSRSGNTLLAAWAS----------- 542
Query: 433 KMPSLSFSVCQFLFFSLLHGI 453
++ SL+ SV +F +L I
Sbjct: 543 RIASLTGSVVNLVFILILSKI 563
>gi|218084958 anoctamin 4 [Homo sapiens]
Length = 920
Score = 100 bits (249), Expect = 5e-21
Identities = 135/539 (25%), Positives = 203/539 (37%), Gaps = 176/539 (32%)
Query: 254 KLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHWD 313
K++ LFD+ TVFF++FM+ W + A +A+ W
Sbjct: 382 KVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDW-------------------- 421
Query: 314 CSDFQDQEVMPSSALHHWDCSDFQDQEECPHLQFAA-LALQMTQNPVTGLKEPYFQPHSC 372
D D++++EE QF A + + NP++G EPY
Sbjct: 422 ------------------DLIDWEEEEEEIRPQFEAKYSKKERMNPISGKPEPYQAFTDK 463
Query: 373 LSHLLTSSAAILTVLCVVMIFLVSVIIYHGIISIAMFH---------------TGNSV-- 415
S L+ S++ I ++CVV+ + ++IY +++++ F TG +V
Sbjct: 464 CSRLIVSASGIFFMICVVIAAVFGIVIYR-VVTVSTFAAFKWALIRNNSQVATTGTAVCI 522
Query: 416 ---LMTQANVL-------------------WGNGGDASM------KMPSLSFSVCQFL-- 445
++ NVL W N M + S +F + FL
Sbjct: 523 NFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGR 582
Query: 446 -------FFSLLHGILQRQCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFVGLGGGP---- 494
+ L++ +C P GC I + Q+ IIMV KQ N+ E G P
Sbjct: 583 FTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMEL----GYPLIQN 638
Query: 495 -----------GPDTPC-LPE-----------------------LQFGFITIFVGAFLLA 519
GP+ P+ LQFGF TIFV AF LA
Sbjct: 639 WWTRRKVRQEHGPERKISFPQWEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLA 698
Query: 520 PLFTLLNNRVEIGLDAHKFLCKYQRPMAGRGWTSGSDCSCWRPCELILPRTNA------- 572
PL LLNN +EI LDA+KF+ +++RP+A R G ++ TNA
Sbjct: 699 PLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITS 758
Query: 573 --RSRLGYWLN-----GQGQ-----ILGRRRGGNAGFGVEIREPLQTPQP---------- 610
RL Y GQG+ ++G + F + E P+
Sbjct: 759 DFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPL 818
Query: 611 ---RYKASRD-----VGVNLALFYWKLLAVHVHLGFIIAFENVVFFFLCPNDRLVPDVP 661
RY+ RD V L +W +LA L FII FE++VF L+PD+P
Sbjct: 819 KYCRYRDYRDPPHSLVPYGYTLQFWHVLA--ARLAFIIVFEHLVFCIKHLISYLIPDLP 875
Score = 39.7 bits (91), Expect = 0.010
Identities = 15/23 (65%), Positives = 16/23 (69%)
Query: 227 NSCQLLYPYWACWGYWHKYQPLD 249
N LLY WA WG W+KYQPLD
Sbjct: 280 NHRHLLYECWASWGVWYKYQPLD 302
>gi|209862785 anoctamin 2 [Homo sapiens]
Length = 998
Score = 92.0 bits (227), Expect = 2e-18
Identities = 127/512 (24%), Positives = 203/512 (39%), Gaps = 118/512 (23%)
Query: 256 SCLFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQE--AMPSSAPHHWD 313
S LFD+P TVFFSIFM+ W + L + WD + +++E A S P +
Sbjct: 428 SHLFDNPATVFFSIFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEHSRPEYET 487
Query: 314 -----CSDFQDQEVMPSSALHHWDCSDFQDQEECPH--------LQFAALA--LQMTQNP 358
+Q + + +C D D+++ + FA++ + +T +
Sbjct: 488 KVREKMLKESNQSAVQKLETNTTECGDEDDEDKLTWKDRFPGYLMNFASILFMIALTFSI 547
Query: 359 VTGLKEPYFQPHSCLS--HLLTSSAAILTVLCVVMIFLVSVIIYHGII-SIAMFHTGNSV 415
V G+ + LS S+ + V+I LV ++I I ++A + T V
Sbjct: 548 VFGVIVYRITTAAALSLNKATRSNVRVTVTATAVIINLVVILILDEIYGAVAKWLTKIEV 607
Query: 416 LMTQAN--------VLWGNGGDASMKMPSLSFSVCQFL-----FFSLLHGILQRQCGPGG 462
T+ +A + ++F +F+ + + G +C PGG
Sbjct: 608 PKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGG 667
Query: 463 CHIQVTQQLIIIMVGKQLLN---------------------------------HMEEFVG 489
C +++ QL IIM+GKQL+ H E++
Sbjct: 668 CLMELCIQLSIIMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQW-D 726
Query: 490 LGGGPGPDTPCLPE-----LQFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFLCKYQR 544
L P T PE +QFGF+T+FV +F LAP+F LLNN +E+ LDA KF+ + +R
Sbjct: 727 LDYSLEPYTGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTELRR 786
Query: 545 PMAGRGWTSG---------SDCSCWRPCELILPRTNARSRL----GYWLNGQ-------- 583
P A R G S +I ++ RL Y NG
Sbjct: 787 PDAVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGTLHGFVNHT 846
Query: 584 ------GQILGRRRGGNAGFGVEI--------REPLQTPQPRYKASRDVGVNLALFYWKL 629
Q+ + N+ F E+ REP P P Y+ S+ YW +
Sbjct: 847 LSFFNVSQLKEGTQPENSQFDQEVQFCRFKDYREPPWAPNP-YEFSKQ--------YWFI 897
Query: 630 LAVHVHLGFIIAFENVVFFFLCPNDRLVPDVP 661
L+ L F+I F+N+V F D ++PD+P
Sbjct: 898 LS--ARLAFVIIFQNLVMFLSVLVDWMIPDIP 927
Score = 40.8 bits (94), Expect = 0.004
Identities = 26/70 (37%), Positives = 38/70 (54%), Gaps = 9/70 (12%)
Query: 188 VAEILDRTISRKKKHTEMGIAHLLG--LFELP------GYQVPGSDLNSCQLLYPYWACW 239
V EIL RT + +T MGI L+ ++E Y P D+N +LLY WA +
Sbjct: 277 VHEILKRTACSRANNT-MGINSLIANNIYEAAYPLHDGEYDSPEDDMNDRKLLYQEWARY 335
Query: 240 GYWHKYQPLD 249
G ++K+QP+D
Sbjct: 336 GVFYKFQPID 345
>gi|156766084 transmembrane protein 16C [Homo sapiens]
Length = 981
Score = 87.4 bits (215), Expect = 4e-17
Identities = 122/522 (23%), Positives = 187/522 (35%), Gaps = 158/522 (30%)
Query: 254 KLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHWD 313
K++ LFD+ GTVFF+IFM+ W + W
Sbjct: 462 KVTYLFDNGGTVFFAIFMAIW-----------ATVFLEFW-------------------- 490
Query: 314 CSDFQDQEVMPSSALHHWDCSDFQDQEECPHLQFAALALQMT-QNPVTGLKEPYFQPHSC 372
+ S + WD +++++EE QF A +M NP+TG EP+
Sbjct: 491 -------KRRRSILTYTWDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPSSDK 543
Query: 373 LSHLLTSSAAILTVLCVVMIFLVSVIIYHGII--SIAMFHTG-----------------N 413
++ LL S + I ++ +V+ + V++Y ++ A F N
Sbjct: 544 VTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAAVCIN 603
Query: 414 SVLMTQANVL-------------------WGNGGDASM---KMPSLSFSVCQFLFF---- 447
+++ N+ W N M + +L+ S+ FF
Sbjct: 604 FIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRF 663
Query: 448 --------SLLHGILQRQCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFVGLGGGP----- 494
L +C P GC I + Q+ +IM KQ+ N+ E G P
Sbjct: 664 VGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMEL----GYPLIQNW 719
Query: 495 --------GPDTPCLPE-----------------------LQFGFITIFVGAFLLAPLFT 523
G +P+ LQFGF TIFV AF LAPL
Sbjct: 720 WSRHKIKRGIHDASIPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLA 779
Query: 524 LLNNRVEIGLDAHKFLCKYQRPMAGRGWTSGSDCSCWRPCELILPRTNA----------- 572
LLNN +EI LDA+KF+ +++RP+ R G ++ TNA
Sbjct: 780 LLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIP 839
Query: 573 ----RSRLGYWLN----GQGQILGRRRGGNAGFGVEIREPLQTPQPRYKASR-----DVG 619
+ G N + + G + F + ++ RY+ R
Sbjct: 840 RFVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKP 899
Query: 620 VNLALFYWKLLAVHVHLGFIIAFENVVFFFLCPNDRLVPDVP 661
L YW +LA L FII FE++VF L+PDVP
Sbjct: 900 YEFTLQYWHILA--ARLAFIIVFEHLVFGIKSFIAYLIPDVP 939
Score = 37.7 bits (86), Expect = 0.037
Identities = 14/23 (60%), Positives = 17/23 (73%)
Query: 227 NSCQLLYPYWACWGYWHKYQPLD 249
N+ LLY WA WG W+K+QPLD
Sbjct: 360 NNRHLLYERWARWGMWYKHQPLD 382
>gi|194306539 anoctamin 1, calcium activated chloride channel [Homo
sapiens]
Length = 986
Score = 78.2 bits (191), Expect = 3e-14
Identities = 77/269 (28%), Positives = 115/269 (42%), Gaps = 66/269 (24%)
Query: 457 QCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFVGLGG-------------GPGPDTPCL-- 501
+C PGGC +++ QL IIM+GKQL+ + +G+ P C+
Sbjct: 650 ECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKR 709
Query: 502 -----------------PE-----LQFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFL 539
PE +QFGF+T+FV +F LAPLF LLNN +EI LDA KF+
Sbjct: 710 KQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFV 769
Query: 540 CKYQRPMAGRGWTSGSDCSCWRPCELILPRTNA-----------RSRLGYWLNGQGQILG 588
+ +RP+A R G + R + NA R Y + G + G
Sbjct: 770 TELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHG 829
Query: 589 RRRGGNAGF-------GVEIREPL----QTPQPRYKASRDV-----GVNLALFYWKLLAV 632
+ F G +PL + RYK R+ +++ +W +LA
Sbjct: 830 FVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLA- 888
Query: 633 HVHLGFIIAFENVVFFFLCPNDRLVPDVP 661
L F+I F+N+V F D ++PD+P
Sbjct: 889 -ARLAFVIVFQNLVMFMSDFVDWVIPDIP 916
Score = 42.7 bits (99), Expect = 0.001
Identities = 19/56 (33%), Positives = 29/56 (51%)
Query: 254 KLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAP 309
+ S LFD+P TVFFS+FM+ W + L + WD + F+++E P
Sbjct: 399 RASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHP 454
Score = 40.0 bits (92), Expect = 0.008
Identities = 27/70 (38%), Positives = 37/70 (52%), Gaps = 9/70 (12%)
Query: 188 VAEILDRTISRKKKHTEMGIAHLL--GLFELP------GYQVPGSDLNSCQLLYPYWACW 239
V EIL RT K K++ MGI LL G++ Y + N +LLY WA +
Sbjct: 250 VYEILKRTTCTKAKYS-MGITSLLANGVYAAAYPLHDGDYNGENVEFNDRKLLYEEWARY 308
Query: 240 GYWHKYQPLD 249
G ++KYQP+D
Sbjct: 309 GVFYKYQPID 318
>gi|218156307 anoctamin 6 isoform c [Homo sapiens]
Length = 929
Score = 69.3 bits (168), Expect = 1e-11
Identities = 96/404 (23%), Positives = 158/404 (39%), Gaps = 98/404 (24%)
Query: 229 CQLLYPYWACWGYWHKYQPLDQPLDKLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSAT 288
C L P+W K + KL C+FD GT+ F++FM W + A
Sbjct: 351 CDRLCPFW-------KLNITCESSKKL-CIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAE 402
Query: 289 LAHHWDCSDFQ-DQEAMP---SSAPHHWDCSDFQDQEVMPSSALHHWDCSDFQDQEECPH 344
L + WD + Q +++A P + H Q++E +P +A W +C
Sbjct: 403 LEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPFTA---WG--------KCIR 451
Query: 345 LQFAALAL-----------------QMTQNPVTGLKEPY-FQPHSCLSHLLTSSAAILTV 386
+ A A+ +++ V K P + LT A ++
Sbjct: 452 ITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTAT-SI 510
Query: 387 LCVVMIFLVSVIIYHGIISIAMFHTGNSVLMTQANVLWGNGGDASMKMPSLSF----SVC 442
++ F++ +I+ +A+ T + TQ + +MKM F S C
Sbjct: 511 TASIISFIIIMILNTIYEKVAIMITNFELPRTQTDY----ENSLTMKMFLFQFVNYYSSC 566
Query: 443 QFLFFSL-------------LHGILQRQCGPGGCHIQVTQQLIIIMVGKQLLNHMEE--- 486
++ F L +C PGGC +++T QL IIM GK + N+++E
Sbjct: 567 FYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLL 626
Query: 487 --FVGLGG------GPGPDTPCLPE--------------------LQFGFITIFVGAFLL 518
+ L G G TP + +QFGF+T+FV +F L
Sbjct: 627 PWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPL 686
Query: 519 APLFTLLNNRVEIGLDAHKFLCKYQRPMAGRGWTSGSDCSCWRP 562
APL L+NN +EI +DA K +++R + + D W+P
Sbjct: 687 APLLALVNNILEIRVDAWKLTTQFRRLVPEK----AQDIGAWQP 726
>gi|218156305 anoctamin 6 isoform c [Homo sapiens]
Length = 929
Score = 69.3 bits (168), Expect = 1e-11
Identities = 96/404 (23%), Positives = 158/404 (39%), Gaps = 98/404 (24%)
Query: 229 CQLLYPYWACWGYWHKYQPLDQPLDKLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSAT 288
C L P+W K + KL C+FD GT+ F++FM W + A
Sbjct: 351 CDRLCPFW-------KLNITCESSKKL-CIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAE 402
Query: 289 LAHHWDCSDFQ-DQEAMP---SSAPHHWDCSDFQDQEVMPSSALHHWDCSDFQDQEECPH 344
L + WD + Q +++A P + H Q++E +P +A W +C
Sbjct: 403 LEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPFTA---WG--------KCIR 451
Query: 345 LQFAALAL-----------------QMTQNPVTGLKEPY-FQPHSCLSHLLTSSAAILTV 386
+ A A+ +++ V K P + LT A ++
Sbjct: 452 ITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTAT-SI 510
Query: 387 LCVVMIFLVSVIIYHGIISIAMFHTGNSVLMTQANVLWGNGGDASMKMPSLSF----SVC 442
++ F++ +I+ +A+ T + TQ + +MKM F S C
Sbjct: 511 TASIISFIIIMILNTIYEKVAIMITNFELPRTQTDY----ENSLTMKMFLFQFVNYYSSC 566
Query: 443 QFLFFSL-------------LHGILQRQCGPGGCHIQVTQQLIIIMVGKQLLNHMEE--- 486
++ F L +C PGGC +++T QL IIM GK + N+++E
Sbjct: 567 FYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLL 626
Query: 487 --FVGLGG------GPGPDTPCLPE--------------------LQFGFITIFVGAFLL 518
+ L G G TP + +QFGF+T+FV +F L
Sbjct: 627 PWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPL 686
Query: 519 APLFTLLNNRVEIGLDAHKFLCKYQRPMAGRGWTSGSDCSCWRP 562
APL L+NN +EI +DA K +++R + + D W+P
Sbjct: 687 APLLALVNNILEIRVDAWKLTTQFRRLVPEK----AQDIGAWQP 726
>gi|218156303 anoctamin 6 isoform b [Homo sapiens]
Length = 892
Score = 69.3 bits (168), Expect = 1e-11
Identities = 96/404 (23%), Positives = 158/404 (39%), Gaps = 98/404 (24%)
Query: 229 CQLLYPYWACWGYWHKYQPLDQPLDKLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSAT 288
C L P+W K + KL C+FD GT+ F++FM W + A
Sbjct: 333 CDRLCPFW-------KLNITCESSKKL-CIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAE 384
Query: 289 LAHHWDCSDFQ-DQEAMP---SSAPHHWDCSDFQDQEVMPSSALHHWDCSDFQDQEECPH 344
L + WD + Q +++A P + H Q++E +P +A W +C
Sbjct: 385 LEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPFTA---WG--------KCIR 433
Query: 345 LQFAALAL-----------------QMTQNPVTGLKEPY-FQPHSCLSHLLTSSAAILTV 386
+ A A+ +++ V K P + LT A ++
Sbjct: 434 ITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTAT-SI 492
Query: 387 LCVVMIFLVSVIIYHGIISIAMFHTGNSVLMTQANVLWGNGGDASMKMPSLSF----SVC 442
++ F++ +I+ +A+ T + TQ + +MKM F S C
Sbjct: 493 TASIISFIIIMILNTIYEKVAIMITNFELPRTQTDY----ENSLTMKMFLFQFVNYYSSC 548
Query: 443 QFLFFSL-------------LHGILQRQCGPGGCHIQVTQQLIIIMVGKQLLNHMEE--- 486
++ F L +C PGGC +++T QL IIM GK + N+++E
Sbjct: 549 FYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLL 608
Query: 487 --FVGLGG------GPGPDTPCLPE--------------------LQFGFITIFVGAFLL 518
+ L G G TP + +QFGF+T+FV +F L
Sbjct: 609 PWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPL 668
Query: 519 APLFTLLNNRVEIGLDAHKFLCKYQRPMAGRGWTSGSDCSCWRP 562
APL L+NN +EI +DA K +++R + + D W+P
Sbjct: 669 APLLALVNNILEIRVDAWKLTTQFRRLVPEK----AQDIGAWQP 708
>gi|218156299 anoctamin 6 isoform a [Homo sapiens]
Length = 910
Score = 69.3 bits (168), Expect = 1e-11
Identities = 96/404 (23%), Positives = 158/404 (39%), Gaps = 98/404 (24%)
Query: 229 CQLLYPYWACWGYWHKYQPLDQPLDKLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSAT 288
C L P+W K + KL C+FD GT+ F++FM W + A
Sbjct: 351 CDRLCPFW-------KLNITCESSKKL-CIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAE 402
Query: 289 LAHHWDCSDFQ-DQEAMP---SSAPHHWDCSDFQDQEVMPSSALHHWDCSDFQDQEECPH 344
L + WD + Q +++A P + H Q++E +P +A W +C
Sbjct: 403 LEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPFTA---WG--------KCIR 451
Query: 345 LQFAALAL-----------------QMTQNPVTGLKEPY-FQPHSCLSHLLTSSAAILTV 386
+ A A+ +++ V K P + LT A ++
Sbjct: 452 ITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTAT-SI 510
Query: 387 LCVVMIFLVSVIIYHGIISIAMFHTGNSVLMTQANVLWGNGGDASMKMPSLSF----SVC 442
++ F++ +I+ +A+ T + TQ + +MKM F S C
Sbjct: 511 TASIISFIIIMILNTIYEKVAIMITNFELPRTQTDY----ENSLTMKMFLFQFVNYYSSC 566
Query: 443 QFLFFSL-------------LHGILQRQCGPGGCHIQVTQQLIIIMVGKQLLNHMEE--- 486
++ F L +C PGGC +++T QL IIM GK + N+++E
Sbjct: 567 FYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLL 626
Query: 487 --FVGLGG------GPGPDTPCLPE--------------------LQFGFITIFVGAFLL 518
+ L G G TP + +QFGF+T+FV +F L
Sbjct: 627 PWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPL 686
Query: 519 APLFTLLNNRVEIGLDAHKFLCKYQRPMAGRGWTSGSDCSCWRP 562
APL L+NN +EI +DA K +++R + + D W+P
Sbjct: 687 APLLALVNNILEIRVDAWKLTTQFRRLVPEK----AQDIGAWQP 726
>gi|218081589 anoctamin 5 isoform b [Homo sapiens]
Length = 912
Score = 66.2 bits (160), Expect = 1e-10
Identities = 44/129 (34%), Positives = 63/129 (48%), Gaps = 31/129 (24%)
Query: 457 QCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFV---------------------------- 488
+C PGGC I++T QL IIM GKQ+ +++E +
Sbjct: 599 ECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTNSEKLYSRWEQDH 658
Query: 489 --GLGGGPGPDTPCLPEL-QFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFLCKYQRP 545
G G L + QFGF+T+FV +F LAPL L+NN VEI +DA K +Y+R
Sbjct: 659 DLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRT 718
Query: 546 MAGRGWTSG 554
+A + + G
Sbjct: 719 VASKAHSIG 727
Score = 47.4 bits (111), Expect = 5e-05
Identities = 40/169 (23%), Positives = 69/169 (40%), Gaps = 40/169 (23%)
Query: 254 KLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHWD 313
K S LFD+ TVFF+IFM W + A L + WD DF++++
Sbjct: 372 KFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQ----------- 420
Query: 314 CSDFQDQEVMPSSALHHWDCSDFQDQEECPHLQFAALALQMTQNPVTGLKEPYFQPHSCL 373
Q ++ P +F A+ N VT EPY ++ +
Sbjct: 421 ----QQLQLRP---------------------EFEAMCKHRKLNAVTKEMEPYMPLYTRI 455
Query: 374 SHLLTSSAAILTVLCVVMIFLVSVIIYHGIISIAMFHTGNSVLMTQANV 422
S A + + +V+ +V+VI+Y +++F T S + + A++
Sbjct: 456 PWYFLSGATVTLWMSLVVTSMVAVIVYR----LSVFATFASFMESDASL 500
>gi|47106048 anoctamin 5 isoform a [Homo sapiens]
Length = 913
Score = 66.2 bits (160), Expect = 1e-10
Identities = 44/129 (34%), Positives = 63/129 (48%), Gaps = 31/129 (24%)
Query: 457 QCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFV---------------------------- 488
+C PGGC I++T QL IIM GKQ+ +++E +
Sbjct: 600 ECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTNSEKLYSRWEQDH 659
Query: 489 --GLGGGPGPDTPCLPEL-QFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFLCKYQRP 545
G G L + QFGF+T+FV +F LAPL L+NN VEI +DA K +Y+R
Sbjct: 660 DLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRT 719
Query: 546 MAGRGWTSG 554
+A + + G
Sbjct: 720 VASKAHSIG 728
Score = 47.4 bits (111), Expect = 5e-05
Identities = 40/169 (23%), Positives = 69/169 (40%), Gaps = 40/169 (23%)
Query: 254 KLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHWD 313
K S LFD+ TVFF+IFM W + A L + WD DF++++
Sbjct: 373 KFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQ----------- 421
Query: 314 CSDFQDQEVMPSSALHHWDCSDFQDQEECPHLQFAALALQMTQNPVTGLKEPYFQPHSCL 373
Q ++ P +F A+ N VT EPY ++ +
Sbjct: 422 ----QQLQLRP---------------------EFEAMCKHRKLNAVTKEMEPYMPLYTRI 456
Query: 374 SHLLTSSAAILTVLCVVMIFLVSVIIYHGIISIAMFHTGNSVLMTQANV 422
S A + + +V+ +V+VI+Y +++F T S + + A++
Sbjct: 457 PWYFLSGATVTLWMSLVVTSMVAVIVYR----LSVFATFASFMESDASL 501
>gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens]
Length = 782
Score = 63.2 bits (152), Expect = 8e-10
Identities = 134/554 (24%), Positives = 195/554 (35%), Gaps = 127/554 (22%)
Query: 244 KYQPLDQPLD--KLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQ 301
+YQ L + KL+ LFD+ GTV F+IFM+ W + A + HWD
Sbjct: 245 RYQRLSETCTFAKLTHLFDNDGTVVFAIFMALWATVFLEIWKRQRARVVLHWDL------ 298
Query: 302 EAMPSSAPHHWDCSDFQDQEVMPSSALHHWDCSDFQDQEECPHLQFAALALQMTQNPVT- 360
+ WD ++QE M AL +C D++ + + + L +T +
Sbjct: 299 --------YVWD----EEQEEM---ALQLINCPDYKLRPYQHSYLRSTVILVLTLLMICL 343
Query: 361 --GLKEPYFQPHSCLSHLLTSSAAILTVLCVVMIFLVSVIIYHGIISIAMFHTGNSVLMT 418
G+ S L +SSA V +V+ + H + I M V +
Sbjct: 344 MIGMAHVLVVYRVLASALFSSSAVPFLEEQVTTAVVVTGALVHYVTIIIMTKINRCVALK 403
Query: 419 QANVLWGNGGDASMKMPSLSFSVCQFL--FFSLLH--GILQR------------------ 456
+ ++ F QF F SL++ IL R
Sbjct: 404 LCDFEMPRTFSERESRFTIRFFTLQFFTHFSSLIYIAFILGRINGHPGKSTRLAGLWKLE 463
Query: 457 QCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFV---------GLGGGPGPDTPCLPEL--- 504
+C GC + + Q+ IIM KQ L++ E++ L P PEL
Sbjct: 464 ECHASGCMMDLFVQMAIIMGLKQTLSNCVEYLVPWVTHKCRSLRASESGHLPRDPELRDW 523
Query: 505 -----------------------QFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFLCK 541
Q+GF TIFV AF LAPL L +N VEI LDA K +
Sbjct: 524 RRNYLLNPVNTFSLFDEFMEMMIQYGFTTIFVAAFPLAPLLALFSNLVEIRLDAIKMVW- 582
Query: 542 YQRPMAGRGWTSGSDCSCW-RPCELI------------------LPRTNARSRLGYWLNG 582
QR + R D W + E I +PR + R L
Sbjct: 583 LQRRLVPR---KAKDIGTWLQVLETIGVLAVIANGMVIAFTSEFIPRVVYKYRYSPCLKE 639
Query: 583 QGQILGRRRG-GNAGFGVEIREPLQTPQP----------RYKASRD-VGVNLALFYWKLL 630
+ +G N V + Q P RY+ R+ N + +W LL
Sbjct: 640 GNSTVDCLKGYVNHSLSVFHTKDFQDPDGIEGSENVTLCRYRDYRNPPDYNFSEQFWFLL 699
Query: 631 AVHVHLGFIIAFENVVFFFLCPNDRLVPDVPA----LATKITARALPGQAGGGRQPGDAV 686
A + L F+I FE+V VPD+P ++ + L + GRQ V
Sbjct: 700 A--IRLAFVILFEHVALCIKLIAAWFVPDIPQSVKNKVLEVKYQRLREKMWHGRQRLGGV 757
Query: 687 SVSKAGGPRPHPQH 700
AG P P H
Sbjct: 758 G---AGSRPPMPAH 768
>gi|55741655 anoctamin 8 [Homo sapiens]
Length = 1232
Score = 42.4 bits (98), Expect = 0.002
Identities = 21/46 (45%), Positives = 27/46 (58%)
Query: 504 LQFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFLCKYQRPMAGR 549
+QFG++ +F AF LA L L+NN +EI DA K QRP R
Sbjct: 753 VQFGYVVLFSSAFPLAALCALVNNLIEIRSDAFKLCTGLQRPFGQR 798
>gi|94536803 transmembrane protein 16K [Homo sapiens]
Length = 660
Score = 37.7 bits (86), Expect = 0.037
Identities = 17/44 (38%), Positives = 27/44 (61%)
Query: 504 LQFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFLCKYQRPMA 547
LQFG++++F + LA F +LNN E+ DA K ++RP +
Sbjct: 503 LQFGYVSLFSCVYPLAAAFAVLNNFTEVNSDALKMCRVFKRPFS 546
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 37.0 bits (84), Expect = 0.064
Identities = 40/123 (32%), Positives = 52/123 (42%), Gaps = 11/123 (8%)
Query: 53 RWVRLRA-RLGGEAATPAAAGERRLR--QRRWRENFQRNLEEVSTEPAGCETRGRAQTPL 109
RW R R+ + G + +P G R R QRR R R S PA R R++TP
Sbjct: 521 RWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPA-TRGRSRSRTPA 579
Query: 110 ASSETRTRAFSSSSVKWIWPPGPTPTLRARRSHGDACACATLCSSRCPAGRRIRAPSAAR 169
+R+R + + TPT R RS A + SR PA RR R S R
Sbjct: 580 RRGRSRSRTPARRRSR-----SRTPTRRRSRSRTPARRGRS--RSRTPARRRSRTRSPVR 632
Query: 170 SRT 172
R+
Sbjct: 633 RRS 635
Score = 32.0 bits (71), Expect = 2.1
Identities = 35/123 (28%), Positives = 43/123 (34%), Gaps = 21/123 (17%)
Query: 56 RLRARLGGEAATPAAAGERRLR---QRRWRENFQRNLEEVSTEPAGCETRGRAQTPLASS 112
R R + TPA G R R +RR R S PA R R++TP
Sbjct: 597 RTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRG 656
Query: 113 ETRTRAFSSSSVKWIWPPGPTPTLRARRSHGDACACATLCSSRCPAGR---RIRAPSAAR 169
+R+R TP R R + SR PA R R R P R
Sbjct: 657 RSRSR---------------TPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGR 701
Query: 170 SRT 172
SR+
Sbjct: 702 SRS 704
>gi|169168296 PREDICTED: hypothetical protein [Homo sapiens]
Length = 359
Score = 34.7 bits (78), Expect = 0.32
Identities = 36/135 (26%), Positives = 52/135 (38%), Gaps = 10/135 (7%)
Query: 50 LTPRWVRLRARLGGEAATPAAAGERRLRQRRWRENFQRNLEEVSTE-PAGCETRGRAQTP 108
L P W G E G RL + + R+ + E P ++RGR Q+P
Sbjct: 211 LPPGWSPRTTDPGQEVQADCGGG--RLASAQLPQGLPRSAGLPAREQPPPTQSRGRLQSP 268
Query: 109 LASSETRTRAFSSSSVKWIWPPGPTPTLRARRSHGDACACATLCSSRCPAGRRIRAPSAA 168
A + + A + S P GP R+ G +C+ + G R+R PSA
Sbjct: 269 CAREASTSPALTPRSQYPKRPQGPA------RNRG-SCSPPLSVTLAVTEGPRLRKPSAP 321
Query: 169 RSRTTGTLSGQLTRG 183
T+ Q TRG
Sbjct: 322 EENTSAPSPTQSTRG 336
>gi|169168044 PREDICTED: hypothetical protein [Homo sapiens]
Length = 359
Score = 34.7 bits (78), Expect = 0.32
Identities = 36/135 (26%), Positives = 52/135 (38%), Gaps = 10/135 (7%)
Query: 50 LTPRWVRLRARLGGEAATPAAAGERRLRQRRWRENFQRNLEEVSTE-PAGCETRGRAQTP 108
L P W G E G RL + + R+ + E P ++RGR Q+P
Sbjct: 211 LPPGWSPRTTDPGQEVQADCGGG--RLASAQLPQGLPRSAGLPAREQPPPTQSRGRLQSP 268
Query: 109 LASSETRTRAFSSSSVKWIWPPGPTPTLRARRSHGDACACATLCSSRCPAGRRIRAPSAA 168
A + + A + S P GP R+ G +C+ + G R+R PSA
Sbjct: 269 CAREASTSPALTPRSQYPKRPQGPA------RNRG-SCSPPLSVTLAVTEGPRLRKPSAP 321
Query: 169 RSRTTGTLSGQLTRG 183
T+ Q TRG
Sbjct: 322 EENTSAPSPTQSTRG 336
>gi|169167512 PREDICTED: hypothetical protein [Homo sapiens]
Length = 442
Score = 34.7 bits (78), Expect = 0.32
Identities = 36/135 (26%), Positives = 52/135 (38%), Gaps = 10/135 (7%)
Query: 50 LTPRWVRLRARLGGEAATPAAAGERRLRQRRWRENFQRNLEEVSTE-PAGCETRGRAQTP 108
L P W G E G RL + + R+ + E P ++RGR Q+P
Sbjct: 294 LPPGWSPRTTDPGQEVQADCGGG--RLASAQLPQGLPRSAGLPAREQPPPTQSRGRLQSP 351
Query: 109 LASSETRTRAFSSSSVKWIWPPGPTPTLRARRSHGDACACATLCSSRCPAGRRIRAPSAA 168
A + + A + S P GP R+ G +C+ + G R+R PSA
Sbjct: 352 CAREASTSPALTPRSQYPKRPQGPA------RNRG-SCSPPLSVTLAVTEGPRLRKPSAP 404
Query: 169 RSRTTGTLSGQLTRG 183
T+ Q TRG
Sbjct: 405 EENTSAPSPTQSTRG 419
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 34.7 bits (78), Expect = 0.32
Identities = 30/83 (36%), Positives = 35/83 (42%), Gaps = 7/83 (8%)
Query: 62 GGEAATPAAAGERRLRQRRWRENFQRNLEEVSTEPAGCETRGRAQTPLASSETRTRAFSS 121
GG AA A RR R+RR R+ S R R P SS + +RA SS
Sbjct: 376 GGRAAGGAGRRRRRRRRRR------RSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSS 429
Query: 122 S-SVKWIWPPGPTPTLRARRSHG 143
S S PGP P + R HG
Sbjct: 430 SDSGSGRGAPGPGPEPGSERGHG 452
>gi|32490559 low density lipoprotein receptor-related protein 10
precursor [Homo sapiens]
Length = 713
Score = 34.3 bits (77), Expect = 0.41
Identities = 17/59 (28%), Positives = 26/59 (44%), Gaps = 5/59 (8%)
Query: 293 WDCSDFQDQEAMPSSAPHHWDCSDFQDQEV----MPSSALHHWD-CSDFQDQEECPHLQ 346
WDC+D D+E P P H+ C +P+ ++ C+D D+ C H Q
Sbjct: 342 WDCADGTDEEDCPGCPPGHFPCGAAGTSGATACYLPADRCNYQTFCADGADERRCRHCQ 400
>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
Length = 819
Score = 33.1 bits (74), Expect = 0.92
Identities = 36/150 (24%), Positives = 55/150 (36%), Gaps = 26/150 (17%)
Query: 52 PRWVRLRARLG-GEAATPAAAGERRLRQR---------------------RWRENFQRNL 89
PRW R R AA P G ++ R+R R + ++
Sbjct: 402 PRWQNPRRRAQKAPAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKARQKA 461
Query: 90 EEVSTEPAGCETRGRAQTPLASSETRTRAFSSSSVKWIWPPGPTPTLRARRSHGDACACA 149
E E G + +GR + A +++R S S K +W G +A + A A
Sbjct: 462 AEAGAESRGDKKQGRQKASAAGTKSRGGGLKSHSGKNLWRRGQ----KAEAAGEKATAAG 517
Query: 150 TLCSSRCPAGRRIRAPSAARSRTTGTLSGQ 179
R R+ A + A+SR G+ S Q
Sbjct: 518 AKSRGRKQPRRQKPAVAGAKSRVGGSKSRQ 547
>gi|239755599 PREDICTED: hypothetical protein XP_002344618 [Homo
sapiens]
Length = 109
Score = 33.1 bits (74), Expect = 0.92
Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Query: 20 PDSRGTFSETGKPALIKVGQSGVRPLLTVPLTPRWVRLRARLGGEAATPAAAGERRLRQR 79
P +RG S + ++ + ++ RP P R R + A+ AA+ R+R
Sbjct: 22 PATRGAAS-AWRTSVRQPRKAARRPCRWWPRRSRATRSTISVAASASPAAASRAPGARKR 80
Query: 80 RWRENFQRNLEEVSTEPAGCETR 102
RW+ + R E+S P C +R
Sbjct: 81 RWKRSSARTSSELSPPPCSCASR 103
>gi|239750090 PREDICTED: hypothetical protein XP_002347290 [Homo
sapiens]
Length = 109
Score = 33.1 bits (74), Expect = 0.92
Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Query: 20 PDSRGTFSETGKPALIKVGQSGVRPLLTVPLTPRWVRLRARLGGEAATPAAAGERRLRQR 79
P +RG S + ++ + ++ RP P R R + A+ AA+ R+R
Sbjct: 22 PATRGAAS-AWRTSVRQPRKAARRPCRWWPRRSRATRSTISVAASASPAAASRAPGARKR 80
Query: 80 RWRENFQRNLEEVSTEPAGCETR 102
RW+ + R E+S P C +R
Sbjct: 81 RWKRSSARTSSELSPPPCSCASR 103
>gi|239744399 PREDICTED: hypothetical protein XP_002343154 [Homo
sapiens]
Length = 109
Score = 33.1 bits (74), Expect = 0.92
Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Query: 20 PDSRGTFSETGKPALIKVGQSGVRPLLTVPLTPRWVRLRARLGGEAATPAAAGERRLRQR 79
P +RG S + ++ + ++ RP P R R + A+ AA+ R+R
Sbjct: 22 PATRGAAS-AWRTSVRQPRKAARRPCRWWPRRSRATRSTISVAASASPAAASRAPGARKR 80
Query: 80 RWRENFQRNLEEVSTEPAGCETR 102
RW+ + R E+S P C +R
Sbjct: 81 RWKRSSARTSSELSPPPCSCASR 103
>gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo
sapiens]
Length = 542
Score = 32.3 bits (72), Expect = 1.6
Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 2/59 (3%)
Query: 663 LATKITARALPGQAGGGRQPGDAVSVSKAGGPRPHPQHND--HNDHAPWPALKLQLSPL 719
+AT A + GQ GGG +P A +V AG PQ D ++ A KL L PL
Sbjct: 1 MATATIALQVNGQQGGGSEPAAAAAVVAAGDKWKPPQGTDSIKMENGQSTAAKLGLPPL 59
>gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo
sapiens]
Length = 559
Score = 32.3 bits (72), Expect = 1.6
Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 2/59 (3%)
Query: 663 LATKITARALPGQAGGGRQPGDAVSVSKAGGPRPHPQHND--HNDHAPWPALKLQLSPL 719
+AT A + GQ GGG +P A +V AG PQ D ++ A KL L PL
Sbjct: 1 MATATIALQVNGQQGGGSEPAAAAAVVAAGDKWKPPQGTDSIKMENGQSTAAKLGLPPL 59
>gi|12965180 taste receptor, type 2, member 10 [Homo sapiens]
Length = 307
Score = 32.0 bits (71), Expect = 2.1
Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 6/77 (7%)
Query: 372 CLSHLLTSSAAILTVLCVVMIFLVSVIIYHGIISI---AMFHTGNSVLMTQANVLWGNGG 428
C + L++ ILT L + IFL+ +II G I I ++ +GN L+ + W G
Sbjct: 35 CAKNKLSTIGFILTGLAISRIFLIWIIITDGFIQIFSPNIYASGN--LIEYISYFWVIGN 92
Query: 429 DASMKMPSLSFSVCQFL 445
+SM + S S+ FL
Sbjct: 93 QSSMWF-ATSLSIFYFL 108
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.139 0.457
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,392,009
Number of Sequences: 37866
Number of extensions: 1656989
Number of successful extensions: 4763
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 4637
Number of HSP's gapped (non-prelim): 133
length of query: 719
length of database: 18,247,518
effective HSP length: 110
effective length of query: 609
effective length of database: 14,082,258
effective search space: 8576095122
effective search space used: 8576095122
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.