Guide to the Human Genome
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Search of human proteins with 239746922

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239746922 PREDICTED: similar to cancer/testis antigen family
147, member B1 isoform 2 [Homo sapiens]
         (294 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239746922 PREDICTED: similar to cancer/testis antigen family ...   579   e-166
gi|113430055 PREDICTED: similar to cancer/testis antigen family ...   548   e-156
gi|239752405 PREDICTED: similar to cancer/testis antigen family ...   528   e-150
gi|224591404 cancer/testis antigen family 147, member B1 [Homo s...   365   e-101
gi|121949802 cancer/testis antigen family 47, member A1 [Homo sa...   338   3e-93
gi|121949798 cancer/testis antigen family 47, member A2 [Homo sa...   338   3e-93
gi|121949773 cancer/testis antigen family 47, member A3 [Homo sa...   338   3e-93
gi|121949771 cancer/testis antigen family 47, member A4 [Homo sa...   338   3e-93
gi|121949796 cancer/testis antigen family 47, member A5 [Homo sa...   338   3e-93
gi|121949794 cancer/testis antigen family 47, member A6 [Homo sa...   338   3e-93
gi|121949792 cancer/testis antigen family 47, member A7 [Homo sa...   338   3e-93
gi|121949790 cancer/testis antigen family 47, member A8 [Homo sa...   338   3e-93
gi|121949788 cancer/testis antigen family 47, member A9 [Homo sa...   338   3e-93
gi|121949786 cancer/testis antigen family 47, member A10 [Homo s...   338   3e-93
gi|122114660 cancer/testis antigen family 47, member A11 [Homo s...   338   3e-93
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    64   2e-10
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     57   1e-08
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    57   1e-08
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    57   1e-08
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              57   3e-08
gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]     56   3e-08
gi|23503317 coiled-coil domain containing 96 [Homo sapiens]            53   3e-07
gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sap...    51   1e-06
gi|156071476 hypothetical protein LOC401137 [Homo sapiens]             51   1e-06
gi|17975763 myelin transcription factor 1 [Homo sapiens]               51   1e-06
gi|221219020 NYD-SP11 protein [Homo sapiens]                           50   2e-06
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    50   2e-06
gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo sap...    50   2e-06
gi|21361639 DIPB protein [Homo sapiens]                                48   1e-05
gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sa...    48   1e-05

>gi|239746922 PREDICTED: similar to cancer/testis antigen family
           147, member B1 isoform 2 [Homo sapiens]
          Length = 294

 Score =  579 bits (1493), Expect = e-166
 Identities = 294/294 (100%), Positives = 294/294 (100%)

Query: 1   MSATGDQDLIQEDQEAPVNQEGAQAEAVGDREGGDSGPDSGNTVAGVAGPMRGLGEEEGE 60
           MSATGDQDLIQEDQEAPVNQEGAQAEAVGDREGGDSGPDSGNTVAGVAGPMRGLGEEEGE
Sbjct: 1   MSATGDQDLIQEDQEAPVNQEGAQAEAVGDREGGDSGPDSGNTVAGVAGPMRGLGEEEGE 60

Query: 61  QAAGLAAAPGGGNAEEDSEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGFRMEFLDM 120
           QAAGLAAAPGGGNAEEDSEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGFRMEFLDM
Sbjct: 61  QAAGLAAAPGGGNAEEDSEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGFRMEFLDM 120

Query: 121 VHSLLLRIYHNDHILIRMRGGRLMRRRRTAAPSGSEEPRLLLVHERLGVGAAGPEGEGLG 180
           VHSLLLRIYHNDHILIRMRGGRLMRRRRTAAPSGSEEPRLLLVHERLGVGAAGPEGEGLG
Sbjct: 121 VHSLLLRIYHNDHILIRMRGGRLMRRRRTAAPSGSEEPRLLLVHERLGVGAAGPEGEGLG 180

Query: 181 LLQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEE 240
           LLQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEE
Sbjct: 181 LLQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEE 240

Query: 241 SAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVKNSKGT 294
           SAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVKNSKGT
Sbjct: 241 SAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVKNSKGT 294


>gi|113430055 PREDICTED: similar to cancer/testis antigen family
           147, member B1 isoform 1 [Homo sapiens]
          Length = 284

 Score =  548 bits (1411), Expect = e-156
 Identities = 284/294 (96%), Positives = 284/294 (96%), Gaps = 10/294 (3%)

Query: 1   MSATGDQDLIQEDQEAPVNQEGAQAEAVGDREGGDSGPDSGNTVAGVAGPMRGLGEEEGE 60
           MSATGDQDLIQEDQEAPVNQEGAQAEAVGDREGGDSGPDSGNTVAGVAGPMRGLGEEEGE
Sbjct: 1   MSATGDQDLIQEDQEAPVNQEGAQAEAVGDREGGDSGPDSGNTVAGVAGPMRGLGEEEGE 60

Query: 61  QAAGLAAAPGGGNAEEDSEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGFRMEFLDM 120
           QAAGLAAAPGGGNAEEDSEIRIVEEEEEEEE RNEADNFDLVAAARRYPIRGFRMEFLDM
Sbjct: 61  QAAGLAAAPGGGNAEEDSEIRIVEEEEEEEE-RNEADNFDLVAAARRYPIRGFRMEFLDM 119

Query: 121 VHSLLLRIYHNDHILIRMRGGRLMRRRRTAAPSGSEEPRLLLVHERLGVGAAGPEGEGLG 180
           VHSLLLRIYHNDHILIRMRGGRLMRRRRTAAPSGSEEPRLLLVHERLGVGAAGPEGEGLG
Sbjct: 120 VHSLLLRIYHNDHILIRMRGGRLMRRRRTAAPSGSEEPRLLLVHERLGVGAAGPEGEGLG 179

Query: 181 LLQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEE 240
           LLQEAALVPEPEVPADLAEMAREPAEEP         AEEELAEEAAEEPAKEEPAAEEE
Sbjct: 180 LLQEAALVPEPEVPADLAEMAREPAEEP---------AEEELAEEAAEEPAKEEPAAEEE 230

Query: 241 SAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVKNSKGT 294
           SAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVKNSKGT
Sbjct: 231 SAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVKNSKGT 284


>gi|239752405 PREDICTED: similar to cancer/testis antigen family
           147, member B1 [Homo sapiens]
          Length = 290

 Score =  528 bits (1359), Expect = e-150
 Identities = 278/297 (93%), Positives = 281/297 (94%), Gaps = 10/297 (3%)

Query: 1   MSATGDQDLIQEDQEAPVNQEGAQAEAVGDREGGDSGPDSGNTVAGVAGPMRGLGEEEGE 60
           MSATGDQDLIQEDQEAPVNQEGAQAEA GDREGGDSGPDSGNTVAGVAGPMRGLGEEEGE
Sbjct: 1   MSATGDQDLIQEDQEAPVNQEGAQAEAGGDREGGDSGPDSGNTVAGVAGPMRGLGEEEGE 60

Query: 61  QAAGLAAAPGGGNAEEDSEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGFRMEFLDM 120
           QAAGLAAAPGGGNAEEDSEIRIV EEEEEEEERNEADNFDLVAAARRYPIRGFRMEFLDM
Sbjct: 61  QAAGLAAAPGGGNAEEDSEIRIV-EEEEEEEERNEADNFDLVAAARRYPIRGFRMEFLDM 119

Query: 121 VHSLLLRIYHNDHILIRMRGGRLMRRRRTAAPSGSEEPRLLLVHERLGVGAAGPEGEGLG 180
           VHSLLLRIYHNDHILIRMRGGRLM R  TAAPSGSEEPRLLLVHERLGVGAAGPEGEGLG
Sbjct: 120 VHSLLLRIYHNDHILIRMRGGRLM-RGXTAAPSGSEEPRLLLVHERLGVGAAGPEGEGLG 178

Query: 181 LLQEAALVPEPEVPADLAEMAREPAEEPAE---EKPTEEAAEEELAEEAAEEPAKEEPAA 237
           LLQEAALVPEPEVPADLAEMAREPAEEP E   EKPTEEAAEEEL+EEAAEEP KEE AA
Sbjct: 179 LLQEAALVPEPEVPADLAEMAREPAEEPTEEASEKPTEEAAEEELSEEAAEEPRKEESAA 238

Query: 238 EEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVKNSKGT 294
           EEESA+EPAT+     EEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVKNSKGT
Sbjct: 239 EEESAQEPATQ-----EEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVKNSKGT 290


>gi|224591404 cancer/testis antigen family 147, member B1 [Homo
           sapiens]
          Length = 299

 Score =  365 bits (937), Expect = e-101
 Identities = 208/309 (67%), Positives = 227/309 (73%), Gaps = 25/309 (8%)

Query: 1   MSATGDQDLIQEDQEAPVNQEGAQAEAVG--DREGGDSGPDSGNTV-----AGVAGPMRG 53
           MSATGD+   Q DQEAPV+QEGAQAEA G  ++EGGDSGPDS + V      GVAGP+ G
Sbjct: 1   MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDMVPAAEVVGVAGPVEG 60

Query: 54  LGEEEGEQAAGLAAAPGGGNAEEDSEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGF 113
           LGEEEGEQAAGLAA P GG+AEEDS+I    EEEEEEEE NEA NFDL  A RRYP  G 
Sbjct: 61  LGEEEGEQAAGLAAVPQGGSAEEDSDIGPATEEEEEEEEGNEAANFDLAVATRRYPAAGI 120

Query: 114 RMEFLDMVHSLLLRIYHNDHILIRMRG-GRLMRRRRTAAPSGSEEPRLLLVHERLGVGAA 172
              FL +VHSLL R+YHNDHI I  R   RLM     A P+  + P LLL+ +RLG GAA
Sbjct: 121 GFVFLYLVHSLLRRLYHNDHIQIANRHLSRLMVGPHAAVPNLWDNPPLLLLSQRLGAGAA 180

Query: 173 GPEGEGLGLL------QEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEA 226
            PEGEGLGL+      QEAA VPEP VPADLAEMAREPAEE A+EKP EEAAEE+L EEA
Sbjct: 181 APEGEGLGLIQEAASVQEAASVPEPAVPADLAEMAREPAEEAADEKPPEEAAEEKLTEEA 240

Query: 227 AEEPAKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKE-EKEKDAE 285
            EEPA          AEEP +EEA APEEVTK Q EKWDEEAQDAAG+EEKE EKEKD E
Sbjct: 241 TEEPA----------AEEPTSEEAVAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDVE 290

Query: 286 NKVKNSKGT 294
           NKVKNSKGT
Sbjct: 291 NKVKNSKGT 299


>gi|121949802 cancer/testis antigen family 47, member A1 [Homo
           sapiens]
          Length = 288

 Score =  338 bits (867), Expect = 3e-93
 Identities = 202/305 (66%), Positives = 220/305 (72%), Gaps = 28/305 (9%)

Query: 1   MSATGDQDLIQEDQEAPVNQEGAQAEAVG--DREGGDSGPDSGNTV-----AGVAGPMRG 53
           MSATGD+   Q DQEAPV+QEGAQAEA G  ++EGGDSGPDS + V      GVAGP+ G
Sbjct: 1   MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEG 60

Query: 54  LGEEEGEQAAGLAAAPGGGNAEEDSEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGF 113
           LGEEEGEQAAGLAA P GG+AEEDS+I    EEEEEEE  NEA NFDL   ARRYP  G 
Sbjct: 61  LGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEG-NEAANFDLAVVARRYPASGI 119

Query: 114 RMEFLDMVHSLLLRIYHNDHILIRMRG-GRLMRRRRTAAPS--GSEEPRLLLVHERLGVG 170
               LDMVHSLL R+ HNDHILI  R   RLM     AA +  G+  P  LL+ +RLG G
Sbjct: 120 HFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPP--LLLPQRLGAG 177

Query: 171 AAGPEGEGLGLLQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEP 230
           AA   GEGLGL+QEAA VPEP VPADLAEMAREPA         EEAAEE+L+EEA EEP
Sbjct: 178 AAARAGEGLGLIQEAASVPEPAVPADLAEMAREPA---------EEAAEEKLSEEATEEP 228

Query: 231 AKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKE-EKEKDAENKVK 289
             EEPA      EEP  +EA APEEVTK Q EKWDEEAQDAAG+EEKE EKEKDAENKVK
Sbjct: 229 DAEEPA-----TEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVK 283

Query: 290 NSKGT 294
           NSKGT
Sbjct: 284 NSKGT 288


>gi|121949798 cancer/testis antigen family 47, member A2 [Homo
           sapiens]
          Length = 288

 Score =  338 bits (867), Expect = 3e-93
 Identities = 202/305 (66%), Positives = 220/305 (72%), Gaps = 28/305 (9%)

Query: 1   MSATGDQDLIQEDQEAPVNQEGAQAEAVG--DREGGDSGPDSGNTV-----AGVAGPMRG 53
           MSATGD+   Q DQEAPV+QEGAQAEA G  ++EGGDSGPDS + V      GVAGP+ G
Sbjct: 1   MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEG 60

Query: 54  LGEEEGEQAAGLAAAPGGGNAEEDSEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGF 113
           LGEEEGEQAAGLAA P GG+AEEDS+I    EEEEEEE  NEA NFDL   ARRYP  G 
Sbjct: 61  LGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEG-NEAANFDLAVVARRYPASGI 119

Query: 114 RMEFLDMVHSLLLRIYHNDHILIRMRG-GRLMRRRRTAAPS--GSEEPRLLLVHERLGVG 170
               LDMVHSLL R+ HNDHILI  R   RLM     AA +  G+  P  LL+ +RLG G
Sbjct: 120 HFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPP--LLLPQRLGAG 177

Query: 171 AAGPEGEGLGLLQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEP 230
           AA   GEGLGL+QEAA VPEP VPADLAEMAREPA         EEAAEE+L+EEA EEP
Sbjct: 178 AAARAGEGLGLIQEAASVPEPAVPADLAEMAREPA---------EEAAEEKLSEEATEEP 228

Query: 231 AKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKE-EKEKDAENKVK 289
             EEPA      EEP  +EA APEEVTK Q EKWDEEAQDAAG+EEKE EKEKDAENKVK
Sbjct: 229 DAEEPA-----TEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVK 283

Query: 290 NSKGT 294
           NSKGT
Sbjct: 284 NSKGT 288


>gi|121949773 cancer/testis antigen family 47, member A3 [Homo
           sapiens]
          Length = 288

 Score =  338 bits (867), Expect = 3e-93
 Identities = 202/305 (66%), Positives = 220/305 (72%), Gaps = 28/305 (9%)

Query: 1   MSATGDQDLIQEDQEAPVNQEGAQAEAVG--DREGGDSGPDSGNTV-----AGVAGPMRG 53
           MSATGD+   Q DQEAPV+QEGAQAEA G  ++EGGDSGPDS + V      GVAGP+ G
Sbjct: 1   MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEG 60

Query: 54  LGEEEGEQAAGLAAAPGGGNAEEDSEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGF 113
           LGEEEGEQAAGLAA P GG+AEEDS+I    EEEEEEE  NEA NFDL   ARRYP  G 
Sbjct: 61  LGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEG-NEAANFDLAVVARRYPASGI 119

Query: 114 RMEFLDMVHSLLLRIYHNDHILIRMRG-GRLMRRRRTAAPS--GSEEPRLLLVHERLGVG 170
               LDMVHSLL R+ HNDHILI  R   RLM     AA +  G+  P  LL+ +RLG G
Sbjct: 120 HFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPP--LLLPQRLGAG 177

Query: 171 AAGPEGEGLGLLQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEP 230
           AA   GEGLGL+QEAA VPEP VPADLAEMAREPA         EEAAEE+L+EEA EEP
Sbjct: 178 AAARAGEGLGLIQEAASVPEPAVPADLAEMAREPA---------EEAAEEKLSEEATEEP 228

Query: 231 AKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKE-EKEKDAENKVK 289
             EEPA      EEP  +EA APEEVTK Q EKWDEEAQDAAG+EEKE EKEKDAENKVK
Sbjct: 229 DAEEPA-----TEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVK 283

Query: 290 NSKGT 294
           NSKGT
Sbjct: 284 NSKGT 288


>gi|121949771 cancer/testis antigen family 47, member A4 [Homo
           sapiens]
          Length = 288

 Score =  338 bits (867), Expect = 3e-93
 Identities = 202/305 (66%), Positives = 220/305 (72%), Gaps = 28/305 (9%)

Query: 1   MSATGDQDLIQEDQEAPVNQEGAQAEAVG--DREGGDSGPDSGNTV-----AGVAGPMRG 53
           MSATGD+   Q DQEAPV+QEGAQAEA G  ++EGGDSGPDS + V      GVAGP+ G
Sbjct: 1   MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEG 60

Query: 54  LGEEEGEQAAGLAAAPGGGNAEEDSEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGF 113
           LGEEEGEQAAGLAA P GG+AEEDS+I    EEEEEEE  NEA NFDL   ARRYP  G 
Sbjct: 61  LGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEG-NEAANFDLAVVARRYPASGI 119

Query: 114 RMEFLDMVHSLLLRIYHNDHILIRMRG-GRLMRRRRTAAPS--GSEEPRLLLVHERLGVG 170
               LDMVHSLL R+ HNDHILI  R   RLM     AA +  G+  P  LL+ +RLG G
Sbjct: 120 HFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPP--LLLPQRLGAG 177

Query: 171 AAGPEGEGLGLLQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEP 230
           AA   GEGLGL+QEAA VPEP VPADLAEMAREPA         EEAAEE+L+EEA EEP
Sbjct: 178 AAARAGEGLGLIQEAASVPEPAVPADLAEMAREPA---------EEAAEEKLSEEATEEP 228

Query: 231 AKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKE-EKEKDAENKVK 289
             EEPA      EEP  +EA APEEVTK Q EKWDEEAQDAAG+EEKE EKEKDAENKVK
Sbjct: 229 DAEEPA-----TEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVK 283

Query: 290 NSKGT 294
           NSKGT
Sbjct: 284 NSKGT 288


>gi|121949796 cancer/testis antigen family 47, member A5 [Homo
           sapiens]
          Length = 288

 Score =  338 bits (867), Expect = 3e-93
 Identities = 202/305 (66%), Positives = 220/305 (72%), Gaps = 28/305 (9%)

Query: 1   MSATGDQDLIQEDQEAPVNQEGAQAEAVG--DREGGDSGPDSGNTV-----AGVAGPMRG 53
           MSATGD+   Q DQEAPV+QEGAQAEA G  ++EGGDSGPDS + V      GVAGP+ G
Sbjct: 1   MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEG 60

Query: 54  LGEEEGEQAAGLAAAPGGGNAEEDSEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGF 113
           LGEEEGEQAAGLAA P GG+AEEDS+I    EEEEEEE  NEA NFDL   ARRYP  G 
Sbjct: 61  LGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEG-NEAANFDLAVVARRYPASGI 119

Query: 114 RMEFLDMVHSLLLRIYHNDHILIRMRG-GRLMRRRRTAAPS--GSEEPRLLLVHERLGVG 170
               LDMVHSLL R+ HNDHILI  R   RLM     AA +  G+  P  LL+ +RLG G
Sbjct: 120 HFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPP--LLLPQRLGAG 177

Query: 171 AAGPEGEGLGLLQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEP 230
           AA   GEGLGL+QEAA VPEP VPADLAEMAREPA         EEAAEE+L+EEA EEP
Sbjct: 178 AAARAGEGLGLIQEAASVPEPAVPADLAEMAREPA---------EEAAEEKLSEEATEEP 228

Query: 231 AKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKE-EKEKDAENKVK 289
             EEPA      EEP  +EA APEEVTK Q EKWDEEAQDAAG+EEKE EKEKDAENKVK
Sbjct: 229 DAEEPA-----TEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVK 283

Query: 290 NSKGT 294
           NSKGT
Sbjct: 284 NSKGT 288


>gi|121949794 cancer/testis antigen family 47, member A6 [Homo
           sapiens]
          Length = 288

 Score =  338 bits (867), Expect = 3e-93
 Identities = 202/305 (66%), Positives = 220/305 (72%), Gaps = 28/305 (9%)

Query: 1   MSATGDQDLIQEDQEAPVNQEGAQAEAVG--DREGGDSGPDSGNTV-----AGVAGPMRG 53
           MSATGD+   Q DQEAPV+QEGAQAEA G  ++EGGDSGPDS + V      GVAGP+ G
Sbjct: 1   MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEG 60

Query: 54  LGEEEGEQAAGLAAAPGGGNAEEDSEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGF 113
           LGEEEGEQAAGLAA P GG+AEEDS+I    EEEEEEE  NEA NFDL   ARRYP  G 
Sbjct: 61  LGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEG-NEAANFDLAVVARRYPASGI 119

Query: 114 RMEFLDMVHSLLLRIYHNDHILIRMRG-GRLMRRRRTAAPS--GSEEPRLLLVHERLGVG 170
               LDMVHSLL R+ HNDHILI  R   RLM     AA +  G+  P  LL+ +RLG G
Sbjct: 120 HFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPP--LLLPQRLGAG 177

Query: 171 AAGPEGEGLGLLQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEP 230
           AA   GEGLGL+QEAA VPEP VPADLAEMAREPA         EEAAEE+L+EEA EEP
Sbjct: 178 AAARAGEGLGLIQEAASVPEPAVPADLAEMAREPA---------EEAAEEKLSEEATEEP 228

Query: 231 AKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKE-EKEKDAENKVK 289
             EEPA      EEP  +EA APEEVTK Q EKWDEEAQDAAG+EEKE EKEKDAENKVK
Sbjct: 229 DAEEPA-----TEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVK 283

Query: 290 NSKGT 294
           NSKGT
Sbjct: 284 NSKGT 288


>gi|121949792 cancer/testis antigen family 47, member A7 [Homo
           sapiens]
          Length = 288

 Score =  338 bits (867), Expect = 3e-93
 Identities = 202/305 (66%), Positives = 220/305 (72%), Gaps = 28/305 (9%)

Query: 1   MSATGDQDLIQEDQEAPVNQEGAQAEAVG--DREGGDSGPDSGNTV-----AGVAGPMRG 53
           MSATGD+   Q DQEAPV+QEGAQAEA G  ++EGGDSGPDS + V      GVAGP+ G
Sbjct: 1   MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEG 60

Query: 54  LGEEEGEQAAGLAAAPGGGNAEEDSEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGF 113
           LGEEEGEQAAGLAA P GG+AEEDS+I    EEEEEEE  NEA NFDL   ARRYP  G 
Sbjct: 61  LGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEG-NEAANFDLAVVARRYPASGI 119

Query: 114 RMEFLDMVHSLLLRIYHNDHILIRMRG-GRLMRRRRTAAPS--GSEEPRLLLVHERLGVG 170
               LDMVHSLL R+ HNDHILI  R   RLM     AA +  G+  P  LL+ +RLG G
Sbjct: 120 HFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPP--LLLPQRLGAG 177

Query: 171 AAGPEGEGLGLLQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEP 230
           AA   GEGLGL+QEAA VPEP VPADLAEMAREPA         EEAAEE+L+EEA EEP
Sbjct: 178 AAARAGEGLGLIQEAASVPEPAVPADLAEMAREPA---------EEAAEEKLSEEATEEP 228

Query: 231 AKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKE-EKEKDAENKVK 289
             EEPA      EEP  +EA APEEVTK Q EKWDEEAQDAAG+EEKE EKEKDAENKVK
Sbjct: 229 DAEEPA-----TEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVK 283

Query: 290 NSKGT 294
           NSKGT
Sbjct: 284 NSKGT 288


>gi|121949790 cancer/testis antigen family 47, member A8 [Homo
           sapiens]
          Length = 288

 Score =  338 bits (867), Expect = 3e-93
 Identities = 202/305 (66%), Positives = 220/305 (72%), Gaps = 28/305 (9%)

Query: 1   MSATGDQDLIQEDQEAPVNQEGAQAEAVG--DREGGDSGPDSGNTV-----AGVAGPMRG 53
           MSATGD+   Q DQEAPV+QEGAQAEA G  ++EGGDSGPDS + V      GVAGP+ G
Sbjct: 1   MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEG 60

Query: 54  LGEEEGEQAAGLAAAPGGGNAEEDSEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGF 113
           LGEEEGEQAAGLAA P GG+AEEDS+I    EEEEEEE  NEA NFDL   ARRYP  G 
Sbjct: 61  LGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEG-NEAANFDLAVVARRYPASGI 119

Query: 114 RMEFLDMVHSLLLRIYHNDHILIRMRG-GRLMRRRRTAAPS--GSEEPRLLLVHERLGVG 170
               LDMVHSLL R+ HNDHILI  R   RLM     AA +  G+  P  LL+ +RLG G
Sbjct: 120 HFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPP--LLLPQRLGAG 177

Query: 171 AAGPEGEGLGLLQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEP 230
           AA   GEGLGL+QEAA VPEP VPADLAEMAREPA         EEAAEE+L+EEA EEP
Sbjct: 178 AAARAGEGLGLIQEAASVPEPAVPADLAEMAREPA---------EEAAEEKLSEEATEEP 228

Query: 231 AKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKE-EKEKDAENKVK 289
             EEPA      EEP  +EA APEEVTK Q EKWDEEAQDAAG+EEKE EKEKDAENKVK
Sbjct: 229 DAEEPA-----TEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVK 283

Query: 290 NSKGT 294
           NSKGT
Sbjct: 284 NSKGT 288


>gi|121949788 cancer/testis antigen family 47, member A9 [Homo
           sapiens]
          Length = 288

 Score =  338 bits (867), Expect = 3e-93
 Identities = 202/305 (66%), Positives = 220/305 (72%), Gaps = 28/305 (9%)

Query: 1   MSATGDQDLIQEDQEAPVNQEGAQAEAVG--DREGGDSGPDSGNTV-----AGVAGPMRG 53
           MSATGD+   Q DQEAPV+QEGAQAEA G  ++EGGDSGPDS + V      GVAGP+ G
Sbjct: 1   MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEG 60

Query: 54  LGEEEGEQAAGLAAAPGGGNAEEDSEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGF 113
           LGEEEGEQAAGLAA P GG+AEEDS+I    EEEEEEE  NEA NFDL   ARRYP  G 
Sbjct: 61  LGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEG-NEAANFDLAVVARRYPASGI 119

Query: 114 RMEFLDMVHSLLLRIYHNDHILIRMRG-GRLMRRRRTAAPS--GSEEPRLLLVHERLGVG 170
               LDMVHSLL R+ HNDHILI  R   RLM     AA +  G+  P  LL+ +RLG G
Sbjct: 120 HFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPP--LLLPQRLGAG 177

Query: 171 AAGPEGEGLGLLQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEP 230
           AA   GEGLGL+QEAA VPEP VPADLAEMAREPA         EEAAEE+L+EEA EEP
Sbjct: 178 AAARAGEGLGLIQEAASVPEPAVPADLAEMAREPA---------EEAAEEKLSEEATEEP 228

Query: 231 AKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKE-EKEKDAENKVK 289
             EEPA      EEP  +EA APEEVTK Q EKWDEEAQDAAG+EEKE EKEKDAENKVK
Sbjct: 229 DAEEPA-----TEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVK 283

Query: 290 NSKGT 294
           NSKGT
Sbjct: 284 NSKGT 288


>gi|121949786 cancer/testis antigen family 47, member A10 [Homo
           sapiens]
          Length = 288

 Score =  338 bits (867), Expect = 3e-93
 Identities = 202/305 (66%), Positives = 220/305 (72%), Gaps = 28/305 (9%)

Query: 1   MSATGDQDLIQEDQEAPVNQEGAQAEAVG--DREGGDSGPDSGNTV-----AGVAGPMRG 53
           MSATGD+   Q DQEAPV+QEGAQAEA G  ++EGGDSGPDS + V      GVAGP+ G
Sbjct: 1   MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEG 60

Query: 54  LGEEEGEQAAGLAAAPGGGNAEEDSEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGF 113
           LGEEEGEQAAGLAA P GG+AEEDS+I    EEEEEEE  NEA NFDL   ARRYP  G 
Sbjct: 61  LGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEG-NEAANFDLAVVARRYPASGI 119

Query: 114 RMEFLDMVHSLLLRIYHNDHILIRMRG-GRLMRRRRTAAPS--GSEEPRLLLVHERLGVG 170
               LDMVHSLL R+ HNDHILI  R   RLM     AA +  G+  P  LL+ +RLG G
Sbjct: 120 HFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPP--LLLPQRLGAG 177

Query: 171 AAGPEGEGLGLLQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEP 230
           AA   GEGLGL+QEAA VPEP VPADLAEMAREPA         EEAAEE+L+EEA EEP
Sbjct: 178 AAARAGEGLGLIQEAASVPEPAVPADLAEMAREPA---------EEAAEEKLSEEATEEP 228

Query: 231 AKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKE-EKEKDAENKVK 289
             EEPA      EEP  +EA APEEVTK Q EKWDEEAQDAAG+EEKE EKEKDAENKVK
Sbjct: 229 DAEEPA-----TEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVK 283

Query: 290 NSKGT 294
           NSKGT
Sbjct: 284 NSKGT 288


>gi|122114660 cancer/testis antigen family 47, member A11 [Homo
           sapiens]
          Length = 288

 Score =  338 bits (867), Expect = 3e-93
 Identities = 202/305 (66%), Positives = 220/305 (72%), Gaps = 28/305 (9%)

Query: 1   MSATGDQDLIQEDQEAPVNQEGAQAEAVG--DREGGDSGPDSGNTV-----AGVAGPMRG 53
           MSATGD+   Q DQEAPV+QEGAQAEA G  ++EGGDSGPDS + V      GVAGP+ G
Sbjct: 1   MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEG 60

Query: 54  LGEEEGEQAAGLAAAPGGGNAEEDSEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGF 113
           LGEEEGEQAAGLAA P GG+AEEDS+I    EEEEEEE  NEA NFDL   ARRYP  G 
Sbjct: 61  LGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEG-NEAANFDLAVVARRYPASGI 119

Query: 114 RMEFLDMVHSLLLRIYHNDHILIRMRG-GRLMRRRRTAAPS--GSEEPRLLLVHERLGVG 170
               LDMVHSLL R+ HNDHILI  R   RLM     AA +  G+  P  LL+ +RLG G
Sbjct: 120 HFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPP--LLLPQRLGAG 177

Query: 171 AAGPEGEGLGLLQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEP 230
           AA   GEGLGL+QEAA VPEP VPADLAEMAREPA         EEAAEE+L+EEA EEP
Sbjct: 178 AAARAGEGLGLIQEAASVPEPAVPADLAEMAREPA---------EEAAEEKLSEEATEEP 228

Query: 231 AKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKE-EKEKDAENKVK 289
             EEPA      EEP  +EA APEEVTK Q EKWDEEAQDAAG+EEKE EKEKDAENKVK
Sbjct: 229 DAEEPA-----TEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVK 283

Query: 290 NSKGT 294
           NSKGT
Sbjct: 284 NSKGT 288


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
            sapiens]
          Length = 1152

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 76/282 (26%), Positives = 100/282 (35%), Gaps = 59/282 (20%)

Query: 12   EDQEAPVNQEGAQAEAVGDREGGDSGPDSGNTVAGVAGPMRGLGEEEGEQAAGLAAAPGG 71
            E +E     EG + E  G+ E G+   + G       G   G GEEEGE+  G      G
Sbjct: 825  EREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGE-EGEGEEEGEEGEGEGEEEEG 883

Query: 72   -GNAEEDSEIRIVEEE-----EEEEEERNEADNFDLVAAARRYPIRGFRMEFLDMVHSLL 125
             G  EE+ E    EEE     EEE E   E +  +                         
Sbjct: 884  EGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGE------------------------- 918

Query: 126  LRIYHNDHILIRMRGGRLMRRRRTAAPSGSEEPRLLLVHERLGVGAAGPEGEGLGLLQEA 185
                           G+           G EE          G G  G +GEG G  +E 
Sbjct: 919  ---------------GKGEEEGEEGEGEGEEEE---------GEGE-GEDGEGEGEEEEG 953

Query: 186  ALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEP 245
                E E      E   E   E  E +  EE  E E  EE  EE  +EE   EEE   E 
Sbjct: 954  EWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEG 1013

Query: 246  ATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENK 287
              EE    E   + + E+ + E ++  G+EE EE+EK+ E +
Sbjct: 1014 EEEEEGEVE--GEVEGEEGEGEGEEEEGEEEGEEREKEGEGE 1053



 Score = 55.8 bits (133), Expect = 4e-08
 Identities = 74/298 (24%), Positives = 94/298 (31%), Gaps = 77/298 (25%)

Query: 11   QEDQEAPVNQEGAQAEAVGDREGGDSGPDSGNTVAGVAGPMRGLGEEEGEQAAGLAAAPG 70
            +E +E    +EG + E  G+ E G+   +      G      G GEEEGE         G
Sbjct: 860  EEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEG--EEEEG 917

Query: 71   GGNAEEDSEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGFRMEFLDMVHSLLLRIYH 130
             G  EE+ E    E E E EEE  E +  D                              
Sbjct: 918  EGKGEEEGE----EGEGEGEEEEGEGEGED------------------------------ 943

Query: 131  NDHILIRMRGGRLMRRRRTAAPSGSEEPRLLLVHERLGVGAAGPEGEGLGLLQEAALVPE 190
                                   G EE       E  G G    EGEG G         E
Sbjct: 944  -------------------GEGEGEEEEGEWEGEEEEGEGEGEEEGEGEG--------EE 976

Query: 191  PEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEP-----------AKEEPAAEE 239
             E   +  E   E  EE  EE+  EE   EE  E   EE             + E   EE
Sbjct: 977  GEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEE 1036

Query: 240  ESAEEPATE---EAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVKNSKGT 294
            E  EE   E   E    E     + E+ +E      G+EE E ++ +   KV   KG+
Sbjct: 1037 EEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGS 1094



 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 67/293 (22%), Positives = 102/293 (34%), Gaps = 37/293 (12%)

Query: 5   GDQDLIQEDQEAPVNQEGAQAEAVGDREGGDSGPDSGNTVAGVAGPMRGLGEEEGEQAAG 64
           G++   +E ++    +   + E  G+ E G+   + G+          G  E EGE+  G
Sbjct: 707 GEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEG 766

Query: 65  LAAAPGGGNAEEDSEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGFRMEFLDMVHSL 124
                 G   +E+   +  EE+ EEE ++ E +  +          RG   E    V   
Sbjct: 767 EREKEEGERKKEERAGK--EEKGEEEGDQGEGEEEETEG-------RGEEKEEGGEVEGG 817

Query: 125 LLRIYHNDHILIRMRGGRLMRRRRTAAPSGSEEPRLLLVHERLGVGAAGPEGEGLGLLQE 184
                        +  G+  R        G EE               G E EG G  +E
Sbjct: 818 ------------EVEEGKGEREEEEEEGEGEEEE------------GEGEEEEGEGEEEE 853

Query: 185 AALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEE----PAKEEPAAEEE 240
                E E      E   E  E   EE+  E   EEE   E  EE      +EE   E E
Sbjct: 854 GEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGE 913

Query: 241 SAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVKNSKG 293
             E     E    E   + + E+ + E +D  G+ E+EE E + E +    +G
Sbjct: 914 EEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEG 966



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 29/97 (29%), Positives = 40/97 (41%), Gaps = 4/97 (4%)

Query: 5    GDQDLIQEDQEAPVNQEGAQAEAVGDREGGDS----GPDSGNTVAGVAGPMRGLGEEEGE 60
            G+ +  +E+ E    +EG + E  G+ E G+     G   G    G        GE EGE
Sbjct: 908  GEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGE 967

Query: 61   QAAGLAAAPGGGNAEEDSEIRIVEEEEEEEEERNEAD 97
            +        G G  EE+      EEEE EEE   E +
Sbjct: 968  EEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGE 1004



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 35/137 (25%), Positives = 58/137 (42%), Gaps = 11/137 (8%)

Query: 167 LGVGAAGPEGEGLGLLQEAALVPEP---------EVPADLAEMAR--EPAEEPAEEKPTE 215
           +G    GPEG G G  +E +   E          E      EM R  E  +E AE++  +
Sbjct: 644 VGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWK 703

Query: 216 EAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKE 275
           +   EE  ++  E+  ++E   E E   E    E    E   + + EK  E  ++  G+E
Sbjct: 704 KRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEE 763

Query: 276 EKEEKEKDAENKVKNSK 292
            + E+EK+   + K  +
Sbjct: 764 VEGEREKEEGERKKEER 780



 Score = 35.0 bits (79), Expect = 0.079
 Identities = 32/111 (28%), Positives = 48/111 (43%), Gaps = 14/111 (12%)

Query: 5    GDQDLIQEDQEAPVNQEGAQAEAVGDREG-GDSGPDSGNTVAGVAGPMRGLGE---EEGE 60
            G+++  + + E    +E  + E  G+ EG G+   +    V G      G GE   EEGE
Sbjct: 981  GEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGE 1040

Query: 61   QAAGLAAAPGGGNAEEDSEIRIVEEEEE--------EEEERNEADNFDLVA 103
            +        G G  EE+   R  EEEEE        EE ER + + +  V+
Sbjct: 1041 EEGEEREKEGEG--EENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVS 1089


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 42/120 (35%), Positives = 58/120 (48%), Gaps = 7/120 (5%)

Query: 171 AAGPEGEGLGLLQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEP 230
           A G E E      E A  PE E  + + E A+ PAE  + EK   ++  E  + E A+ P
Sbjct: 494 AEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSP 553

Query: 231 AKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVKN 290
           AKEE  +  E A+ P  EEA +P EV      K  E+A+  A +E K   E  +  K K+
Sbjct: 554 AKEEAKSPPE-AKSPEKEEAKSPAEV------KSPEKAKSPAKEEAKSPAEAKSPEKAKS 606



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 37/89 (41%), Positives = 46/89 (51%), Gaps = 9/89 (10%)

Query: 206 EEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAE-------EPATEEAAAPEEVTK 258
           E+  E + TEE  EEE  +EA EE  KEE   EEE AE        P  EEAA+PE+  K
Sbjct: 459 EQTEETQVTEEVTEEE-EKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAK 517

Query: 259 YQHEKWDEEAQDAAGKEEKEEKEKDAENK 287
               K + ++   A   EKEE +  AE K
Sbjct: 518 -SPVKEEAKSPAEAKSPEKEEAKSPAEVK 545



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 47/163 (28%), Positives = 73/163 (44%), Gaps = 29/163 (17%)

Query: 151 APSGSEEPRLLLVHERLGVGAAGPEGEGLGLLQEAALVP---------EPEVPADLA--E 199
           A  G EE +     E     AA PE E    ++E A  P         E + PA++   E
Sbjct: 494 AEGGEEETKSPPAEE-----AASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPE 548

Query: 200 MAREPAEEPAEEKPTEEAAEEELAE--------EAAEEPAKEEP-----AAEEESAEEPA 246
            A+ PA+E A+  P  ++ E+E A+        E A+ PAKEE      A   E A+ P 
Sbjct: 549 KAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPV 608

Query: 247 TEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVK 289
            EEA +P E      E+    A+  + ++ K   +++A++  K
Sbjct: 609 KEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEK 651



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 34/109 (31%), Positives = 53/109 (48%), Gaps = 5/109 (4%)

Query: 183 QEAALVPEPEVPADLAEMAREPAEEPA--EEKPTEEAAEEELAEEAAEE---PAKEEPAA 237
           +E  +V E      + E   E  E+ A  EE   EE  EEE AE   EE   P  EE A+
Sbjct: 452 KETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAAS 511

Query: 238 EEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAEN 286
            E+ A+ P  EEA +P E    + E+    A+  + ++ K   +++A++
Sbjct: 512 PEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKS 560



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 36/115 (31%), Positives = 54/115 (46%), Gaps = 9/115 (7%)

Query: 183 QEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEES- 241
           +EA   PE + P    E A+ PAE  + EK    A EE  +   A+ P K +   +EE+ 
Sbjct: 556 EEAKSPPEAKSPEK--EEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAK 613

Query: 242 ----AEEPATEEAAAPEEVTKYQHEK--WDEEAQDAAGKEEKEEKEKDAENKVKN 290
               A+ P  EEA +P EV   +  K    EEA+     +  E++E  +  K K+
Sbjct: 614 SPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKS 668



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 40/120 (33%), Positives = 57/120 (47%), Gaps = 5/120 (4%)

Query: 171 AAGPEGEGLGLLQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEP 230
           A  PE     + +EA    E + P  + E A+ PAE  + EK      EE  + E A+ P
Sbjct: 598 AKSPEKAKSPVKEEAKSPAEAKSP--VKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSP 655

Query: 231 AKEEPAAEEESAEEPATEEAAAPEEV-TKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVK 289
            KEE A   E A+ P   EA +PE+  +  + E    E   +  KEE +  EK A++ VK
Sbjct: 656 EKEE-AKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEK-AKSPVK 713



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 34/106 (32%), Positives = 48/106 (45%), Gaps = 5/106 (4%)

Query: 189 PEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPA---AEEESAEEP 245
           P+ E P    E  +EPA E  +E   E   EE   ++    P KE PA    +E++  + 
Sbjct: 865 PKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKE 924

Query: 246 ATEEAAAPEEVTKYQHEKWDEEAQDAAG--KEEKEEKEKDAENKVK 289
            TE A    +  K +      E ++AA   K+ KEEK K  E K K
Sbjct: 925 KTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPK 970



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 36/108 (33%), Positives = 58/108 (53%), Gaps = 8/108 (7%)

Query: 182 LQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEES 241
           L+E A  PE E+P    E  + P +E  EEKP +E   +E  ++A EE A   P  EE  
Sbjct: 803 LKEDAKAPEKEIPK--KEEVKSPVKE--EEKP-QEVKVKEPPKKAEEEKAPATPKTEE-- 855

Query: 242 AEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVK 289
            ++ + +E A  +E  K + E+  E A +   + + E K+++AE+K K
Sbjct: 856 -KKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKK 902



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 31/96 (32%), Positives = 44/96 (45%), Gaps = 3/96 (3%)

Query: 199 EMAREPAEEPAE--EKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAPEEV 256
           E A+ P +E A+  EK      EE  + E A+ P KEE A   E A+ P  EEA +PE+ 
Sbjct: 692 EKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEE-AKTPEKAKSPVKEEAKSPEKA 750

Query: 257 TKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVKNSK 292
              +  K  +     A    KEE    A+   + +K
Sbjct: 751 KSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAK 786



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 34/108 (31%), Positives = 50/108 (46%), Gaps = 8/108 (7%)

Query: 190 EPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEE---PAAE-EESAEEP 245
           E + P       +E A+ P + K  E+A   ++    A+ PAKEE   PA +  E A+ P
Sbjct: 729 EAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSP 788

Query: 246 ATEEAAAPEEVTKYQHEKWDEEAQDAAGKEE----KEEKEKDAENKVK 289
             EE  +PE+      E      ++   KEE     +E+EK  E KVK
Sbjct: 789 VKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVK 836



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 36/93 (38%), Positives = 45/93 (48%), Gaps = 8/93 (8%)

Query: 199 EMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAPEEVTK 258
           E   E  EE  +  P EEAA  E   + A+ P KEE  +  E A+ P  EEA +P EV  
Sbjct: 491 EEEAEGGEEETKSPPAEEAASPE---KEAKSPVKEEAKSPAE-AKSPEKEEAKSPAEVKS 546

Query: 259 YQHEK--WDEEAQD--AAGKEEKEEKEKDAENK 287
            +  K    EEA+    A   EKEE +  AE K
Sbjct: 547 PEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVK 579



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 40/120 (33%), Positives = 61/120 (50%), Gaps = 12/120 (10%)

Query: 171 AAGPEGEGLGLLQEAALVPEPEVPADLAEMAREPAEEPAEEK-PTEEAAEEELAEEAAEE 229
           A  PE E     +  + V E E P ++    +EP ++  EEK P     EE+   +  E 
Sbjct: 807 AKAPEKEIPKKEEVKSPVKEEEKPQEVK--VKEPPKKAEEEKAPATPKTEEKKDSKKEEA 864

Query: 230 PAKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVK 289
           P KE P  + E  +EPA E+   P+E +K + +K  EEA+D   K++    EK+A  KV+
Sbjct: 865 PKKEAPKPKVEEKKEPAVEK---PKE-SKVEAKK--EEAED---KKKVPTPEKEAPAKVE 915



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 42/129 (32%), Positives = 55/129 (42%), Gaps = 24/129 (18%)

Query: 188 VPEPEVPADLAEMAREPAEE--------PAEEKPTEEAAEEELAEEAA----EEPAKEE- 234
           V  PE      E AR PA++          EE  + E A+  L E+A     E P KEE 
Sbjct: 761 VKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEV 820

Query: 235 --PAAEEESAEEPATEEAAAPEE-----VTKYQHEKWDEEAQDAAGKE----EKEEKEKD 283
             P  EEE  +E   +E     E      T    EK D + ++A  KE    + EEK++ 
Sbjct: 821 KSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEP 880

Query: 284 AENKVKNSK 292
           A  K K SK
Sbjct: 881 AVEKPKESK 889



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 35/121 (28%), Positives = 60/121 (49%), Gaps = 11/121 (9%)

Query: 183  QEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEP----AKE--EPA 236
            +E+ +  + E   D  ++     E PA+ +  E+A  +E  E A +EP    AKE  +PA
Sbjct: 886  KESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPA 945

Query: 237  AEEESAEE---PATEEAAAPEE--VTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVKNS 291
             ++E+A E      E+A  PEE   T+ + ++ D+       K + E+ EK +    K+S
Sbjct: 946  EKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDS 1005

Query: 292  K 292
            K
Sbjct: 1006 K 1006



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 38/121 (31%), Positives = 56/121 (46%), Gaps = 22/121 (18%)

Query: 194 PADLAEMAREPAEEPAEEK--------PTEEAAE---EELAEEAAEEPAKEEPAAEEESA 242
           P   AE  + PA    EEK        P +EA +   EE  E A E+P + +  A++E A
Sbjct: 838 PPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEA 897

Query: 243 EEP---ATEEAAAPEEV-------TKYQHEKWDEEAQDAAGKE-EKEEKEKDAENKVKNS 291
           E+     T E  AP +V        K + E   +E  DA  KE  K  ++K+A  + K++
Sbjct: 898 EDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDT 957

Query: 292 K 292
           K
Sbjct: 958 K 958



 Score = 37.7 bits (86), Expect = 0.012
 Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 6/103 (5%)

Query: 188 VPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEE--ESAEEP 245
           V EP   A+  +    P  E  ++   EEA ++E  +   EE  K+EPA E+  ES  E 
Sbjct: 835 VKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEE--KKEPAVEKPKESKVEA 892

Query: 246 ATEEAAAPEEVTKYQHE--KWDEEAQDAAGKEEKEEKEKDAEN 286
             EEA   ++V   + E     E  +DA  KE+ E  +K+ ++
Sbjct: 893 KKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDD 935



 Score = 37.4 bits (85), Expect = 0.016
 Identities = 29/111 (26%), Positives = 50/111 (45%), Gaps = 5/111 (4%)

Query: 183 QEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAA----EEELAEEAAEEPAKEEPAAE 238
           +EA    E + P      A+E A+ PAE K  E+A     EE  +   A+ P KEE  + 
Sbjct: 570 EEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSP 629

Query: 239 EESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVK 289
            E  + P   ++   EE    +  K  E+ +  + ++ K   + +A++  K
Sbjct: 630 AE-VKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEK 679



 Score = 36.6 bits (83), Expect = 0.027
 Identities = 31/113 (27%), Positives = 59/113 (52%), Gaps = 16/113 (14%)

Query: 188  VPEPEVPADLAEMAR-EP----AEEPAEEKPTEEAAEE--ELAEEAAEEPAKEEPAAEEE 240
            V E   P +  E+A+ EP    A+EP++    +EAA E  +  EE A++P +E+P  E +
Sbjct: 916  VKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKP-EEKPKTEAK 974

Query: 241  SAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVKNSKG 293
            + E+  T        ++K   +   E+A+ ++  ++K+ K  +   + K +KG
Sbjct: 975  AKEDDKT--------LSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKG 1019



 Score = 36.2 bits (82), Expect = 0.035
 Identities = 24/67 (35%), Positives = 39/67 (58%), Gaps = 5/67 (7%)

Query: 227 AEEPAKEEPAAEEESA-EEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAE 285
           +EE  K    +E+E+   E  TEE    EEVT    E+ ++EA++  GKEE+  +E++AE
Sbjct: 440 SEEKIKVVEKSEKETVIVEEQTEETQVTEEVT----EEEEKEAKEEEGKEEEGGEEEEAE 495

Query: 286 NKVKNSK 292
              + +K
Sbjct: 496 GGEEETK 502



 Score = 33.1 bits (74), Expect = 0.30
 Identities = 29/126 (23%), Positives = 49/126 (38%), Gaps = 7/126 (5%)

Query: 171 AAGPEGEGLGLLQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEP 230
           A  PE       +EA    + + P      + E A+ P + +       +   +E A+ P
Sbjct: 646 AKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSP 705

Query: 231 AK-----EEPAAEEESAEEPATEEAAAPEEVTK--YQHEKWDEEAQDAAGKEEKEEKEKD 283
            K     +E A   E A+ P  EEA  PE+      +  K  E+A+     +  + K  +
Sbjct: 706 EKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPE 765

Query: 284 AENKVK 289
           A+   K
Sbjct: 766 AKTPAK 771



 Score = 32.0 bits (71), Expect = 0.67
 Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 8/79 (10%)

Query: 211 EKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQD 270
           EK T    E+    +  EE  +EE   E+E+ EE   EE    EE       +  EE   
Sbjct: 451 EKETVIVEEQTEETQVTEEVTEEE---EKEAKEEEGKEEEGGEEE-----EAEGGEEETK 502

Query: 271 AAGKEEKEEKEKDAENKVK 289
           +   EE    EK+A++ VK
Sbjct: 503 SPPAEEAASPEKEAKSPVK 521


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 71/270 (26%), Positives = 114/270 (42%), Gaps = 23/270 (8%)

Query: 20  QEGAQAEAVG--DREGGDSGPDSGNTVAGVAGPMRGLGEEEGEQAAGLAAAPGGGNAEED 77
           +EG + E  G  + E  D G  S     G +       +EEGEQ  G   A   G   E 
Sbjct: 523 EEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEA 582

Query: 78  SEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGFRMEFLDMVHSLLLRIYHNDHILIR 137
            E + VEE+ EE   + E     LVA A+        +E  +   S + +    +     
Sbjct: 583 KEEKKVEEKSEEVATKEE-----LVADAK--------VEKPEKAKSPVPKSPVEEKGKSP 629

Query: 138 MRGGRLMRRRRTAAPSGSEEPRLLLVHERLGVGAAGPEGEGLGLLQEAALVPEPEVPADL 197
           +    +  + ++  P    E +      +  V   G        ++E A  P P+ P + 
Sbjct: 630 VPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEE 689

Query: 198 AEMAREPA---EEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAP- 253
           A+   E     ++  EEK  +EA +EE  E+  E+P K+ P  E++ AE P  EEA A  
Sbjct: 690 AKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKP-KDVP--EKKKAESPVKEEAVAEV 746

Query: 254 EEVTKYQHEKWDEEAQDAAGKEEKEEKEKD 283
             +TK      ++E ++  GK  ++EKEK+
Sbjct: 747 VTITKSVKVHLEKETKE-EGKPLQQEKEKE 775



 Score = 51.6 bits (122), Expect = 8e-07
 Identities = 38/112 (33%), Positives = 58/112 (51%), Gaps = 7/112 (6%)

Query: 183 QEAALVPEPEVPADLAEMA--REPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEE 240
           +EAA   E E  A+  E+A  + P +  A E   EE  +EE  EE  EE  +E+  A+ +
Sbjct: 489 KEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEE--EEGQEEEEEEDEGAKSD 546

Query: 241 SAEEPATEEAAAPEEVTKYQHE---KWDEEAQDAAGKEEKEEKEKDAENKVK 289
            AEE  +E+  + E+    Q E   + + E ++A  KEEK+ +EK  E   K
Sbjct: 547 QAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATK 598



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 45/151 (29%), Positives = 67/151 (44%), Gaps = 16/151 (10%)

Query: 157 EPRLLLVHERLGVGAAGPEGEGLGLLQEAALVPEPEVPADLAEM---AREPAEEPAEEKP 213
           E  L  + E L V     + E     +E     E EV A  + +   A E  EE  E++ 
Sbjct: 470 EEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEE 529

Query: 214 TEEAAEEELAEEAAEEPAKEEPAAEEESA--------EEPATEEAAAPEEVTKYQHEKWD 265
            E   EEE  +E A+    EE  +E+E +        EE  TE  A  EE    + +K +
Sbjct: 530 EEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVE 589

Query: 266 EEAQDAAGKEE-----KEEKEKDAENKVKNS 291
           E++++ A KEE     K EK + A++ V  S
Sbjct: 590 EKSEEVATKEELVADAKVEKPEKAKSPVPKS 620



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 36/123 (29%), Positives = 55/123 (44%), Gaps = 17/123 (13%)

Query: 182 LQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEE-----------AAEEELAEEAAE-- 228
           ++EA      E+   + E  +E AEE  EE   EE           A   E+ EE  E  
Sbjct: 469 MEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKE 528

Query: 229 -EPAKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQ---DAAGKEEKEEKEKDA 284
            E  +EE   E+E A+    EE  + +E +  + E   EE +   +A G+E + ++EK  
Sbjct: 529 EEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKV 588

Query: 285 ENK 287
           E K
Sbjct: 589 EEK 591



 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 38/124 (30%), Positives = 57/124 (45%), Gaps = 18/124 (14%)

Query: 188 VPEPEVPADLAEMAREPAEEPAEEKPTEE----------AAEEELA-------EEAAEEP 230
           + +P+V A   ++  +  EE  EE   E+          A  EELA       +EAAEE 
Sbjct: 436 IQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEK 495

Query: 231 AKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVKN 290
            +EEP AEEE      +   A   EV + + EK +EE Q+   +E++  K   AE     
Sbjct: 496 -EEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSE 554

Query: 291 SKGT 294
            +G+
Sbjct: 555 KEGS 558



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 37/123 (30%), Positives = 56/123 (45%), Gaps = 17/123 (13%)

Query: 184 EAALVPEPEVPAD---LAEMAREPAEE----PAEEKPTEEAAEEEL----AEEAAEEPAK 232
           E A  P P+ P +    + + + P EE    P  + P EE  +  +     EE  + P  
Sbjct: 611 EKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVS 670

Query: 233 EEPAAEEESAEEPAT--EEAAAPEEVTKYQHEKWDEEAQDAAGKEEK----EEKEKDAEN 286
           + P  E+  +  P +  EEA +  EV K + ++ +E+    A KEEK    EEK KD   
Sbjct: 671 KSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPE 730

Query: 287 KVK 289
           K K
Sbjct: 731 KKK 733



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 43/146 (29%), Positives = 59/146 (40%), Gaps = 8/146 (5%)

Query: 143 LMRRRRTAAPSGSEEPRLL---LVHERLGVGAAGPE---GEGLGLLQEAALVPEPEVPAD 196
           +   ++ AA    EEP      +  ++  V A  PE    EG    +E     E E    
Sbjct: 484 MKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGA 543

Query: 197 LAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAPEEV 256
            ++ A E   E       EE  +EE  E  AE   +E  A EE+  EE + E A   E V
Sbjct: 544 KSDQAEEGGSEKEGSSEKEEGEQEE-GETEAEAEGEEAEAKEEKKVEEKSEEVATKEELV 602

Query: 257 TKYQHEKWDEEAQDAAGKEEKEEKEK 282
              + EK  E+A+    K   EEK K
Sbjct: 603 ADAKVEK-PEKAKSPVPKSPVEEKGK 627


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
           [Homo sapiens]
          Length = 540

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 71/270 (26%), Positives = 114/270 (42%), Gaps = 23/270 (8%)

Query: 20  QEGAQAEAVG--DREGGDSGPDSGNTVAGVAGPMRGLGEEEGEQAAGLAAAPGGGNAEED 77
           +EG + E  G  + E  D G  S     G +       +EEGEQ  G   A   G   E 
Sbjct: 147 EEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEA 206

Query: 78  SEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGFRMEFLDMVHSLLLRIYHNDHILIR 137
            E + VEE+ EE   + E     LVA A+        +E  +   S + +    +     
Sbjct: 207 KEEKKVEEKSEEVATKEE-----LVADAK--------VEKPEKAKSPVPKSPVEEKGKSP 253

Query: 138 MRGGRLMRRRRTAAPSGSEEPRLLLVHERLGVGAAGPEGEGLGLLQEAALVPEPEVPADL 197
           +    +  + ++  P    E +      +  V   G        ++E A  P P+ P + 
Sbjct: 254 VPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEE 313

Query: 198 AEMAREPA---EEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAP- 253
           A+   E     ++  EEK  +EA +EE  E+  E+P K+ P  E++ AE P  EEA A  
Sbjct: 314 AKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKP-KDVP--EKKKAESPVKEEAVAEV 370

Query: 254 EEVTKYQHEKWDEEAQDAAGKEEKEEKEKD 283
             +TK      ++E ++  GK  ++EKEK+
Sbjct: 371 VTITKSVKVHLEKETKE-EGKPLQQEKEKE 399



 Score = 51.6 bits (122), Expect = 8e-07
 Identities = 38/112 (33%), Positives = 58/112 (51%), Gaps = 7/112 (6%)

Query: 183 QEAALVPEPEVPADLAEMA--REPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEE 240
           +EAA   E E  A+  E+A  + P +  A E   EE  +EE  EE  EE  +E+  A+ +
Sbjct: 113 KEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEE--EEGQEEEEEEDEGAKSD 170

Query: 241 SAEEPATEEAAAPEEVTKYQHE---KWDEEAQDAAGKEEKEEKEKDAENKVK 289
            AEE  +E+  + E+    Q E   + + E ++A  KEEK+ +EK  E   K
Sbjct: 171 QAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATK 222



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 45/151 (29%), Positives = 67/151 (44%), Gaps = 16/151 (10%)

Query: 157 EPRLLLVHERLGVGAAGPEGEGLGLLQEAALVPEPEVPADLAEM---AREPAEEPAEEKP 213
           E  L  + E L V     + E     +E     E EV A  + +   A E  EE  E++ 
Sbjct: 94  EEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEE 153

Query: 214 TEEAAEEELAEEAAEEPAKEEPAAEEESA--------EEPATEEAAAPEEVTKYQHEKWD 265
            E   EEE  +E A+    EE  +E+E +        EE  TE  A  EE    + +K +
Sbjct: 154 EEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVE 213

Query: 266 EEAQDAAGKEE-----KEEKEKDAENKVKNS 291
           E++++ A KEE     K EK + A++ V  S
Sbjct: 214 EKSEEVATKEELVADAKVEKPEKAKSPVPKS 244



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 36/123 (29%), Positives = 55/123 (44%), Gaps = 17/123 (13%)

Query: 182 LQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEE-----------AAEEELAEEAAE-- 228
           ++EA      E+   + E  +E AEE  EE   EE           A   E+ EE  E  
Sbjct: 93  MEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKE 152

Query: 229 -EPAKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQ---DAAGKEEKEEKEKDA 284
            E  +EE   E+E A+    EE  + +E +  + E   EE +   +A G+E + ++EK  
Sbjct: 153 EEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKV 212

Query: 285 ENK 287
           E K
Sbjct: 213 EEK 215



 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 38/124 (30%), Positives = 57/124 (45%), Gaps = 18/124 (14%)

Query: 188 VPEPEVPADLAEMAREPAEEPAEEKPTEE----------AAEEELA-------EEAAEEP 230
           + +P+V A   ++  +  EE  EE   E+          A  EELA       +EAAEE 
Sbjct: 60  IQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEK 119

Query: 231 AKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVKN 290
            +EEP AEEE      +   A   EV + + EK +EE Q+   +E++  K   AE     
Sbjct: 120 -EEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSE 178

Query: 291 SKGT 294
            +G+
Sbjct: 179 KEGS 182



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 37/123 (30%), Positives = 56/123 (45%), Gaps = 17/123 (13%)

Query: 184 EAALVPEPEVPAD---LAEMAREPAEE----PAEEKPTEEAAEEEL----AEEAAEEPAK 232
           E A  P P+ P +    + + + P EE    P  + P EE  +  +     EE  + P  
Sbjct: 235 EKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVS 294

Query: 233 EEPAAEEESAEEPAT--EEAAAPEEVTKYQHEKWDEEAQDAAGKEEK----EEKEKDAEN 286
           + P  E+  +  P +  EEA +  EV K + ++ +E+    A KEEK    EEK KD   
Sbjct: 295 KSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPE 354

Query: 287 KVK 289
           K K
Sbjct: 355 KKK 357



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 43/146 (29%), Positives = 59/146 (40%), Gaps = 8/146 (5%)

Query: 143 LMRRRRTAAPSGSEEPRLL---LVHERLGVGAAGPE---GEGLGLLQEAALVPEPEVPAD 196
           +   ++ AA    EEP      +  ++  V A  PE    EG    +E     E E    
Sbjct: 108 MKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGA 167

Query: 197 LAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAPEEV 256
            ++ A E   E       EE  +EE  E  AE   +E  A EE+  EE + E A   E V
Sbjct: 168 KSDQAEEGGSEKEGSSEKEEGEQEE-GETEAEAEGEEAEAKEEKKVEEKSEEVATKEELV 226

Query: 257 TKYQHEKWDEEAQDAAGKEEKEEKEK 282
              + EK  E+A+    K   EEK K
Sbjct: 227 ADAKVEK-PEKAKSPVPKSPVEEKGK 251


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 72/289 (24%), Positives = 102/289 (35%), Gaps = 27/289 (9%)

Query: 2    SATGDQDLIQEDQEAPVNQEGAQAEAVGDREGGDSGPDSGNTVAGVAGPMRGLGEEEGEQ 61
            +A GDQD  Q D    +    A+ EA  + EG ++    G+     A    G  + E E 
Sbjct: 1819 AAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGD-----AQEAEGEAQPESED 1873

Query: 62   AAGLAAAPGGGNAEEDSEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGFRMEFLDMV 121
                 A        ED E    E E + E E  EA   +  A      +     E  D  
Sbjct: 1874 VEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEP 1933

Query: 122  HSLLLRIYHNDHILIRMRGGRLMRRRRTAAPS-GSEEPRLLLVHERLGVGAAGPEGEGLG 180
             S                G         A  + G  +P   ++  +     A PE E + 
Sbjct: 1934 ES---------------EGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVE 1978

Query: 181  LLQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEE--PAKEEPAAE 238
             L+      E E  A   +   E  E P  E   +EA EE   E    E  P  E   A+
Sbjct: 1979 ALEVEVETQEAEGEA---QPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQ 2035

Query: 239  EESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENK 287
            E   E   TE  A PE     +  + +EEAQ+A G+ ++ E E   E++
Sbjct: 2036 EVEGETQKTEGDAQPES-DGVEAPEAEEEAQEAEGEVQEAEGEAHPESE 2083



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 68/276 (24%), Positives = 102/276 (36%), Gaps = 29/276 (10%)

Query: 21   EGAQAEAVGDREGGDSGPDSGNTVAGVAGPM-----RGLGEEEGEQAAGLAAAPGGGNAE 75
            +G  AE    +   D  P S  TV G  G +     +G G +EGE   G        N +
Sbjct: 1702 DGEAAEVAPGKTHTD--PTSTRTVQGAEGGLGPGLSQGPGVDEGEDGEGSQRL----NRD 1755

Query: 76   EDSEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGFRMEFLDMVHSLLLRIYHNDHIL 135
            +D ++   E +   +E   +  N +  A +             +   +      H D++ 
Sbjct: 1756 KDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQ 1815

Query: 136  IRMRGGRLMRRRRTAAPSGSEEPRLLLVHERLGVGAAGPEGEGLGLLQEAALVPEPEVPA 195
                 G      ++    G E P           G A PE EG+         PE E  A
Sbjct: 1816 GEAAAGGDQDPGQSDGAEGIEAPE--------AEGEAQPESEGVE-------APEAEGDA 1860

Query: 196  DLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAP-- 253
              AE   +P  E  E    E  A+ E +E+     A+ E   E E AE P  E+ A P  
Sbjct: 1861 QEAEGEAQPESEDVEAPEAEGEAQPE-SEDVETPEAEWEVQPESEGAEAPEAEKEAQPET 1919

Query: 254  EEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVK 289
            E V   + E  DE   + A  +E EE  ++AE + +
Sbjct: 1920 ESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQ 1955



 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 80/296 (27%), Positives = 104/296 (35%), Gaps = 29/296 (9%)

Query: 3    ATGDQDLIQEDQEAPVNQEGAQAEAVGDREGGDSGPDSGNTVAGVAGPMRGLGEEEGEQA 62
            A G+     ED EAP   EG   EA  + +     P+S     GV    +  GEE  E  
Sbjct: 1989 AEGEAQPESEDVEAP-EAEGEMQEAEEEAQ-----PESD----GVEAQPKSEGEEAQEVE 2038

Query: 63   AGLAAAPGGGNAEEDSEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGFRMEFLDMVH 122
                   G    E D  +   E EEE +E   E    +  A      +     E      
Sbjct: 2039 GETQKTEGDAQPESDG-VEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPE 2097

Query: 123  SLLLRIYHNDHILIRMRGGRLMRRRRTAAPS----------GSEEPRLLLVHERLGVGAA 172
            S  +     +    +  G         A P           G  +P    V  +   G A
Sbjct: 2098 SEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEA 2157

Query: 173  GPEGEGLGLLQEAALVPEPE---VPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEE 229
             PE EG+   QEA    +PE   V A  AE   +P  E  E    E  A+ EL  E  E 
Sbjct: 2158 QPESEGIEA-QEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPEL--EGVEA 2214

Query: 230  P-AKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDA 284
            P A+EE   E E  E P  E  A PE   + Q EK     Q + G  + EE  + +
Sbjct: 2215 PEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEK-KGSPQVSLGDGQSEEASESS 2269



 Score = 52.0 bits (123), Expect = 6e-07
 Identities = 74/306 (24%), Positives = 108/306 (35%), Gaps = 40/306 (13%)

Query: 3    ATGDQDLIQEDQEAPVNQEGAQAEAVGDREGGDSGPDSGNTVAGVAGPMRGLGEEEGE-- 60
            A G+     ED E P  +   Q E+ G             T +  A    G  E E E  
Sbjct: 1879 AEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGA 1938

Query: 61   --QAAGLAAAPGGGNAEEDSEIRIVEEEEEEEEERNEADNFD-LVAAARRYPIRGFRMEF 117
              Q A  AA    G  + +SE+  +E +E EEE + E+++ + L          G     
Sbjct: 1939 EAQEAEEAAQEAEGQTQPESEV--IESQEAEEEAQPESEDVEALEVEVETQEAEGEAQP- 1995

Query: 118  LDMVHSLLLRIYHNDHILIRMRGGRLMRRRRTAAP----------SGSEEPRLLLVHERL 167
                         ++ +      G +      A P          S  EE + +    + 
Sbjct: 1996 ------------ESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQK 2043

Query: 168  GVGAAGPEGEGLGLLQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAA 227
              G A PE +G+   +      E E     AE    P  E  + +  E  A+ E   E  
Sbjct: 2044 TEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPE--SEGV 2101

Query: 228  EEPAKEEPAAEEESAEEPATEEAA--------APEEVTKYQHEKWDEEAQDAAGKEEKEE 279
            E P  E  A + E  E P TE  A        APE   + Q E    EAQDA G+ + E 
Sbjct: 2102 EAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPES 2161

Query: 280  KEKDAE 285
            +  +A+
Sbjct: 2162 EGIEAQ 2167



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 71/296 (23%), Positives = 105/296 (35%), Gaps = 51/296 (17%)

Query: 3    ATGDQDLIQEDQEAPVNQEGAQAEAVGDREGGDSGPDSGNTVAGVAGPMRGLGEEE---G 59
            A GD  + QE +    N E +    +G+ E    G        G     +G G E+   G
Sbjct: 1763 AEGDA-MAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGG-----QGSGHEDNLQG 1816

Query: 60   EQAAGLAAAPGGGNAEEDSEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGFRMEFLD 119
            E AAG    PG  +  E  E    E E + E E  EA   +  A                
Sbjct: 1817 EAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQ--------------- 1861

Query: 120  MVHSLLLRIYHNDHILIRMRGGRLMRRRRTAAPS--GSEEPRLLLVHERLGVGAAGPEGE 177
                                G          AP   G  +P    V          PE E
Sbjct: 1862 -----------------EAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESE 1904

Query: 178  GLGLLQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEP-AKEEPA 236
            G       A  PE E  A     + E  E   E++P  E AE + AEEAA+E   + +P 
Sbjct: 1905 G-------AEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPE 1957

Query: 237  AEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVKNSK 292
            +E   ++E   E     E+V   + E   +EA+  A  E ++ +  +AE +++ ++
Sbjct: 1958 SEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAE 2013



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 69/286 (24%), Positives = 99/286 (34%), Gaps = 55/286 (19%)

Query: 7    QDLIQEDQEAPVNQEGAQAEAVGDREGGDSGPDSGNTVAGVA-GPMRGLGEEEGEQAAGL 65
            Q+  +E Q    + E  + E       G++ P+S +  A  A G M+   EE   ++ G+
Sbjct: 1964 QEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGV 2023

Query: 66   AAAPG--GGNAEE-DSEIRIVE----------EEEEEEEERNEADNFDLVAAARRYPIRG 112
             A P   G  A+E + E +  E          E  E EEE  EA+     A    +P   
Sbjct: 2024 EAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHP--- 2080

Query: 113  FRMEFLDMVHSLLLRIYHNDHILIRMRGGRLMRRRRTAAPSGSEEPRLLLVHERLGVGAA 172
               E +D   +                              G  +P           G  
Sbjct: 2081 -ESEDVDAQEA-----------------------------EGEAQPE--------SEGVE 2102

Query: 173  GPEGEGLGLLQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAK 232
             PE EG     E    PE E  A       E  E   E +P  E  E + AE  A+  ++
Sbjct: 2103 APEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESE 2162

Query: 233  EEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKE 278
               A E E   +P  E   APE   + Q E    EA +A G+ + E
Sbjct: 2163 GIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPE 2208



 Score = 31.6 bits (70), Expect = 0.87
 Identities = 35/116 (30%), Positives = 46/116 (39%), Gaps = 7/116 (6%)

Query: 185  AALVPEPEVPADLAEM-AREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPA-AEEESA 242
            A    E E   D  E  A    E+ AE    EE   EE  E    E  +EE    EE   
Sbjct: 1268 ACATNEDEAERDSEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKT 1327

Query: 243  EEPATEEAAAPEEVTKYQHE-KWDEEAQ----DAAGKEEKEEKEKDAENKVKNSKG 293
            EE   EE    EE  + + E + +EEAQ    +  G E  +E+    E   +  +G
Sbjct: 1328 EEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEG 1383



 Score = 28.5 bits (62), Expect = 7.4
 Identities = 46/226 (20%), Positives = 77/226 (34%), Gaps = 15/226 (6%)

Query: 62   AAGLAAAPGGGNAEEDSEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGFRMEFLDMV 121
            A   A A     AE DSE +      E+  E    +   L          G + E + + 
Sbjct: 1264 ARACACATNEDEAERDSEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLE 1323

Query: 122  HSLLLRIYHNDHILIRMRGGRLMRRRRTAAPSGSEEPRLLLVHERLGVGAAGPEGEGLGL 181
             +            ++  G +L   + T      EE   L   E    G  G + EG+ L
Sbjct: 1324 ET-------KTEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEE--TGGEGLQEEGVQL 1374

Query: 182  LQEAALVPEPEVPADLAEMARE----PAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAA 237
             +E    PE  +  +  E   +    P E     +   EA+  +      ++P +EE A 
Sbjct: 1375 -EEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAG 1433

Query: 238  EEESAEEPATEEAA-APEEVTKYQHEKWDEEAQDAAGKEEKEEKEK 282
               ++ EP   E    P E   +  E     ++  +G + +   EK
Sbjct: 1434 RASASAEPCPAEGTEEPTEPPSHLSETDPSASERQSGSQLEPGLEK 1479


>gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]
          Length = 543

 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 35/85 (41%), Positives = 43/85 (50%), Gaps = 1/85 (1%)

Query: 210 EEKPTEEAAEEELAEEAAEEPAKEEPAAEEE-SAEEPATEEAAAPEEVTKYQHEKWDEEA 268
           E+   EE  E   AEEA +EP  E  A EEE   EE   EEAA  EE  K + E+  EE 
Sbjct: 450 EQIEVEETIEAAKAEEAKDEPPSEGEAEEEEKDKEEAEEEEAAEEEEAAKEESEEAKEEE 509

Query: 269 QDAAGKEEKEEKEKDAENKVKNSKG 293
           +   G+E +E KE + E K     G
Sbjct: 510 EGGEGEEGEETKEAEEEEKKVEGAG 534



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 39/102 (38%), Positives = 58/102 (56%), Gaps = 5/102 (4%)

Query: 182 LQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEES 241
           +QE  +  E  + A  AE A++  E P+E +  EE  ++E AEE  EE A+EE AA+EES
Sbjct: 447 VQEEQIEVEETIEAAKAEEAKD--EPPSEGEAEEEEKDKEEAEE--EEAAEEEEAAKEES 502

Query: 242 AEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKD 283
            E    EE    EE  + +  + +E+  + AG EE+  K+KD
Sbjct: 503 EEAKEEEEGGEGEEGEETKEAEEEEKKVEGAG-EEQAAKKKD 543



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 33/83 (39%), Positives = 48/83 (57%), Gaps = 3/83 (3%)

Query: 205 AEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKW 264
           AEE  +E P+E  AEEE   E  +E A+EE AAEEE A +  +EEA   EE  + +  + 
Sbjct: 463 AEEAKDEPPSEGEAEEE---EKDKEEAEEEEAAEEEEAAKEESEEAKEEEEGGEGEEGEE 519

Query: 265 DEEAQDAAGKEEKEEKEKDAENK 287
            +EA++   K E   +E+ A+ K
Sbjct: 520 TKEAEEEEKKVEGAGEEQAAKKK 542



 Score = 28.9 bits (63), Expect = 5.7
 Identities = 25/89 (28%), Positives = 35/89 (39%), Gaps = 3/89 (3%)

Query: 10  IQEDQ-EAPVNQEGAQAEAVGDREGGDSGPDSGNTVAGVAGPMRGLGEEEG--EQAAGLA 66
           +QE+Q E     E A+AE   D    +   +        A       EEE   E++    
Sbjct: 447 VQEEQIEVEETIEAAKAEEAKDEPPSEGEAEEEEKDKEEAEEEEAAEEEEAAKEESEEAK 506

Query: 67  AAPGGGNAEEDSEIRIVEEEEEEEEERNE 95
               GG  EE  E +  EEEE++ E   E
Sbjct: 507 EEEEGGEGEEGEETKEAEEEEKKVEGAGE 535



 Score = 28.9 bits (63), Expect = 5.7
 Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 8/64 (12%)

Query: 238 EEESAEEPATEEAA--------APEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVK 289
           +EE  E   T EAA         P E    + EK  EEA++    EE+E  ++++E   +
Sbjct: 448 QEEQIEVEETIEAAKAEEAKDEPPSEGEAEEEEKDKEEAEEEEAAEEEEAAKEESEEAKE 507

Query: 290 NSKG 293
             +G
Sbjct: 508 EEEG 511


>gi|23503317 coiled-coil domain containing 96 [Homo sapiens]
          Length = 555

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 49/151 (32%), Positives = 69/151 (45%), Gaps = 23/151 (15%)

Query: 149 TAAPSGSEEPRLLLVHERLGVGAAGPEGEGLGLLQEAALVPEPEVPADLAEMAREPAEEP 208
           TAA   +E P+ L   E  G    G  G      + A   PEPE PA++       AEEP
Sbjct: 61  TAADEQAEAPKGLTAAEAAGEEGPGEPG------RPAEPQPEPEEPAEVG------AEEP 108

Query: 209 AEEKPTEEAAEEELAEEAAEEPAKEEPAAEEE--SAEEPAT-----EEAAAPEEVTKYQH 261
           A+ +P   A  EEL  EA  E  ++    +E    A  P T     E AAAPE  T  + 
Sbjct: 109 AQPEPG--AGPEELEAEAGAEELEQAAEGKEVRFQASLPLTRIDEEEAAAAPEAET--ER 164

Query: 262 EKWDEEAQDAAGKEEKEEKEKDAENKVKNSK 292
            + +EE ++   ++  E KE+D E +   S+
Sbjct: 165 VEGEEEDKEETQRDGAESKERDGEGRPAKSQ 195



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 34/104 (32%), Positives = 41/104 (39%), Gaps = 8/104 (7%)

Query: 189 PEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKE-EPAAEEESAEEPAT 247
           PE E     A      A+E AE  P    A E   EE   EP +  EP  E E   E   
Sbjct: 47  PEEEEEEQAASQGGTAADEQAEA-PKGLTAAEAAGEEGPGEPGRPAEPQPEPEEPAEVGA 105

Query: 248 EEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVKNS 291
           EE A PE           EE +  AG EE E+  +  E + + S
Sbjct: 106 EEPAQPEP------GAGPEELEAEAGAEELEQAAEGKEVRFQAS 143



 Score = 29.6 bits (65), Expect = 3.3
 Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 14/90 (15%)

Query: 196 DLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAPEE 255
           D   +A  P++  A   P       EL  E  EE  +EE AA +      A E+A AP+ 
Sbjct: 17  DGESLAARPSKIKASSGPPTSPEPGELESEPEEE--EEEQAASQGGTA--ADEQAEAPKG 72

Query: 256 VTKYQHEKWDEEAQDAAGKEEKEEKEKDAE 285
           +T          A +AAG+E   E  + AE
Sbjct: 73  LT----------AAEAAGEEGPGEPGRPAE 92


>gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo
           sapiens]
          Length = 528

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 40/108 (37%), Positives = 53/108 (49%), Gaps = 11/108 (10%)

Query: 192 EVPADLAEMAREPAEE--PAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEP-ATE 248
           ++PA  A    EP EE  P    PTEE  EEE  EE  EE  +EE   + E A  P +  
Sbjct: 288 DLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEE--EEEEEEAEEEEEEEDSEEAPPPLSPP 345

Query: 249 EAAAPEEVTKY-----QHEKWDEEAQDAAGK-EEKEEKEKDAENKVKN 290
           + A+P E  K      Q + + + AQ+A  K EE E   KD E  ++N
Sbjct: 346 QPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRN 393



 Score = 34.3 bits (77), Expect = 0.13
 Identities = 27/95 (28%), Positives = 41/95 (43%)

Query: 190 EPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEE 249
           E E    +AE+ RE            + A EE  ++  E  A ++   ++        EE
Sbjct: 123 ERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEE 182

Query: 250 AAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDA 284
           A  PE   K QH+K  EE   AA  ++++E   DA
Sbjct: 183 AEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADA 217


>gi|156071476 hypothetical protein LOC401137 [Homo sapiens]
          Length = 219

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 37/78 (47%), Positives = 40/78 (51%), Gaps = 9/78 (11%)

Query: 186 ALVPEPEVPADLAEMAREPAE------EPAEEKPT--EEAAEEELAEE-AAEEPAKEEPA 236
           A  P    P     +A EPA       EPA E P   E AAE  +A E AAE P   EPA
Sbjct: 130 AAEPAAAAPLTATPVAAEPAAGAPVAAEPAAEAPVGAEPAAEAPVAAEPAAEAPVGVEPA 189

Query: 237 AEEESAEEPATEEAAAPE 254
           AEE S  EPAT + AAPE
Sbjct: 190 AEEPSPAEPATAKPAAPE 207



 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 33/76 (43%), Positives = 36/76 (47%), Gaps = 4/76 (5%)

Query: 186 ALVPEPEVPADLAEMAREP-AEEPAEEKPT--EEAAEEEL-AEEAAEEPAKEEPAAEEES 241
           A  P    PA  A +   P A EPA   P   E AAE  + AE AAE P   EPAAE   
Sbjct: 125 AAPPIAAEPAAAAPLTATPVAAEPAAGAPVAAEPAAEAPVGAEPAAEAPVAAEPAAEAPV 184

Query: 242 AEEPATEEAAAPEEVT 257
             EPA EE +  E  T
Sbjct: 185 GVEPAAEEPSPAEPAT 200



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 29/66 (43%), Positives = 34/66 (51%), Gaps = 9/66 (13%)

Query: 189 PEPEVPADLAEMAREPAEE------PAEEKPT--EEAAEEELA-EEAAEEPAKEEPAAEE 239
           P    PA  A +A EPA E      PA E P   E AAE  +  E AAEEP+  EPA  +
Sbjct: 143 PVAAEPAAGAPVAAEPAAEAPVGAEPAAEAPVAAEPAAEAPVGVEPAAEEPSPAEPATAK 202

Query: 240 ESAEEP 245
            +A EP
Sbjct: 203 PAAPEP 208



 Score = 35.8 bits (81), Expect = 0.046
 Identities = 30/88 (34%), Positives = 33/88 (37%), Gaps = 3/88 (3%)

Query: 195 ADLAEMAREPAEEPAEEKP---TEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAA 251
           A  A  A   A EPA   P   T  AAE       A EPA E P   E +AE P   E A
Sbjct: 120 AAAAPAAPPIAAEPAAAAPLTATPVAAEPAAGAPVAAEPAAEAPVGAEPAAEAPVAAEPA 179

Query: 252 APEEVTKYQHEKWDEEAQDAAGKEEKEE 279
           A   V      +    A+ A  K    E
Sbjct: 180 AEAPVGVEPAAEEPSPAEPATAKPAAPE 207


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 44/134 (32%), Positives = 69/134 (51%), Gaps = 16/134 (11%)

Query: 162 LVHERLGVGAAGPEGEGLGLLQEAA-----------LVPEPEVPADLAEMAREPAEEPAE 210
           LV E LG  AA P    + LLQEAA           L  +PE   ++ E+  E +++   
Sbjct: 179 LVEEDLGQ-AAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCP 237

Query: 211 EKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQD 270
           +   E+AA EE +++      +EE   EEE  EE   EE    EE  + + E+ +EE ++
Sbjct: 238 QS-LEDAASEESSKQKGILSHEEEDEEEEEEEEE---EEEDEEEEEEEEEEEEEEEEEEE 293

Query: 271 AAGKEEKEEKEKDA 284
              +EE+EE+E++A
Sbjct: 294 EEEEEEEEEEEEEA 307



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 30/69 (43%), Positives = 36/69 (52%), Gaps = 2/69 (2%)

Query: 203 EPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAPEEVTKYQHE 262
           E  EE  EE+  EE  EEE  EE  EE  +EE   EEE  EE   EE AAP+ +  +Q +
Sbjct: 259 EEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVI--FQED 316

Query: 263 KWDEEAQDA 271
                AQ A
Sbjct: 317 TSHTSAQKA 325



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 40/125 (32%), Positives = 59/125 (47%), Gaps = 6/125 (4%)

Query: 158 PRLLLVHERLGVGAAGPEGE-GLGLLQEAA---LVPEPEVPADLAEMAREPA--EEPAEE 211
           P ++ + +    GAA  EGE GL +  E A   +    E   DL   + E A  EE +++
Sbjct: 192 PGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQ 251

Query: 212 KPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDA 271
           K      EE+  EE  EE  +E+   EEE  EE   EE    EE  + + E+ +E A D 
Sbjct: 252 KGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDV 311

Query: 272 AGKEE 276
             +E+
Sbjct: 312 IFQED 316



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 26/68 (38%), Positives = 32/68 (47%)

Query: 199 EMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAPEEVTK 258
           E   E  EE  EE+  EE  EEE  EE  EE  +EE   EEE  EE A  +    E+ + 
Sbjct: 260 EDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSH 319

Query: 259 YQHEKWDE 266
              +K  E
Sbjct: 320 TSAQKAPE 327



 Score = 33.5 bits (75), Expect = 0.23
 Identities = 21/70 (30%), Positives = 30/70 (42%)

Query: 190 EPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEE 249
           E E   +  E   E  EE  EE+  EE  EEE  EEAA +   +E  +   + + P    
Sbjct: 271 EEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRG 330

Query: 250 AAAPEEVTKY 259
             +P    +Y
Sbjct: 331 PESPSPKPEY 340



 Score = 30.8 bits (68), Expect = 1.5
 Identities = 25/90 (27%), Positives = 35/90 (38%), Gaps = 15/90 (16%)

Query: 7   QDLIQEDQEAPVNQEGAQAEAVGDREGGDSGPDSGNTVAGVAGPMRGLGEEEGEQAAGLA 66
           QDL  +  E   ++E ++ + +   E  D   +                EEE E+     
Sbjct: 233 QDLCPQSLEDAASEESSKQKGILSHEEEDEEEEE---------------EEEEEEEDEEE 277

Query: 67  AAPGGGNAEEDSEIRIVEEEEEEEEERNEA 96
                   EE+ E    EEEEEEEEE  EA
Sbjct: 278 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEA 307



 Score = 30.0 bits (66), Expect = 2.5
 Identities = 24/86 (27%), Positives = 35/86 (40%), Gaps = 10/86 (11%)

Query: 12  EDQEAPVNQEGAQAEAVGDREGGDSGPDSGNTVAGVAGPMRGLGEEEGEQAAGLAAAPGG 71
           ED E  V     +++ +  +   D+  +  +   G+        EEE E+          
Sbjct: 219 EDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEE--------- 269

Query: 72  GNAEEDSEIRIVEEEEEEEEERNEAD 97
              EED E    EEEEEEEEE  E +
Sbjct: 270 -EEEEDEEEEEEEEEEEEEEEEEEEE 294



 Score = 28.1 bits (61), Expect = 9.6
 Identities = 15/31 (48%), Positives = 18/31 (58%)

Query: 75  EEDSEIRIVEEEEEEEEERNEADNFDLVAAA 105
           EE+ E    EEEEEEEEE  E +  +   AA
Sbjct: 278 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEAA 308


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 30/94 (31%), Positives = 46/94 (48%)

Query: 199  EMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAPEEVTK 258
            E  RE  EE  EE+  EE  E +  EE  E+  ++E   +++  +E   EE    EEV +
Sbjct: 2248 EEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFE 2307

Query: 259  YQHEKWDEEAQDAAGKEEKEEKEKDAENKVKNSK 292
             + E   EE  ++   EE+EE+    E +V   K
Sbjct: 2308 EKEEIMSEEETESLSDEEEEEESCSLEEEVDREK 2341



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 30/98 (30%), Positives = 46/98 (46%), Gaps = 3/98 (3%)

Query: 195  ADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAPE 254
            A   +  +E      +E  +EE   EE+ E   +E  K+E  + EE  EE   EE    E
Sbjct: 2203 AKRGDKPKEKFSSQVDEVESEEHFSEEM-ESLLDELEKQESLSSEE--EEEREEEEEREE 2259

Query: 255  EVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVKNSK 292
            E  + + E+  EE +    + EKEE+EK  + K K  +
Sbjct: 2260 EEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKE 2297



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 36/115 (31%), Positives = 55/115 (47%), Gaps = 6/115 (5%)

Query: 183  QEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAA---EE 239
            +E   + E EV   L    R+  E    +KP E+ + + + E  +EE   EE  +   E 
Sbjct: 2179 EEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQ-VDEVESEEHFSEEMESLLDEL 2237

Query: 240  ESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEK--EKDAENKVKNSK 292
            E  E  ++EE    EE  + + E+  EE ++   +EE EEK  EK+ E K K  K
Sbjct: 2238 EKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKK 2292



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 30/87 (34%), Positives = 44/87 (50%), Gaps = 6/87 (6%)

Query: 201  AREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAPEEVTKYQ 260
            + E   E  E    E   +E L+ E  EE  +EE   EEE  EE   EE    EE  + Q
Sbjct: 2222 SEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEE--EERKEEEEGEEKQ 2279

Query: 261  HEKWDEEAQDAAGKEEKEEKEKDAENK 287
             EK +EE +    K++KE+K+++ + K
Sbjct: 2280 VEKEEEEKK----KKKKEKKKEEVQEK 2302



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 33/105 (31%), Positives = 49/105 (46%), Gaps = 7/105 (6%)

Query: 190  EPEVPADLAEMAREPAEEPAEEKPTEEAA--EEELAEEAAEEPAKEEPAAEEESAEEPAT 247
            E E   +  E+  E  E   EE+  E+    EEE  ++  +E  KEE   +EE  EE   
Sbjct: 2252 EEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEE--K 2309

Query: 248  EEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVKNSK 292
            EE  + EE      E   EE +++   EE+ ++EK+   K K  K
Sbjct: 2310 EEIMSEEETESLSDE---EEEEESCSLEEEVDREKEILKKEKQFK 2351



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 28/77 (36%), Positives = 40/77 (51%), Gaps = 4/77 (5%)

Query: 207  EPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDE 266
            E  E   +EE  E E  EE  EE  +EE   EEE  EE   EE    +E  + + +K ++
Sbjct: 2238 EKQESLSSEEEEEREEEEEREEEEVREE---EEERKEEEEGEEKQVEKEEEEKKKKKKEK 2294

Query: 267  EAQDAAGKEEK-EEKEK 282
            + ++   KEE  EEKE+
Sbjct: 2295 KKEEVQEKEEVFEEKEE 2311



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 32/104 (30%), Positives = 49/104 (47%), Gaps = 9/104 (8%)

Query: 195  ADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPA-------KEEPAAEEESAEEPAT 247
            A++  +  +  EE  + +   +  E+ELA+E  E          KEE   +EE       
Sbjct: 1687 AEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEK 1746

Query: 248  EEAAAPEEVTKYQHEKWDEEAQDAAGKEEK--EEKEKDAENKVK 289
            ++ A  EE   +Q EK  EE    A +EE   +EKEK A++K K
Sbjct: 1747 KKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEK 1790



 Score = 37.4 bits (85), Expect = 0.016
 Identities = 29/78 (37%), Positives = 42/78 (53%), Gaps = 6/78 (7%)

Query: 210  EEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQ 269
            E++ +  + EEE  EE  EE  +EE   EEE  EE   EE    ++V K + EK  ++ +
Sbjct: 2238 EKQESLSSEEEEEREE--EEEREEEEVREEE--EERKEEEEGEEKQVEKEEEEK--KKKK 2291

Query: 270  DAAGKEEKEEKEKDAENK 287
                KEE +EKE+  E K
Sbjct: 2292 KEKKKEEVQEKEEVFEEK 2309



 Score = 30.8 bits (68), Expect = 1.5
 Identities = 27/105 (25%), Positives = 46/105 (43%), Gaps = 8/105 (7%)

Query: 183  QEAALVPEPEVPA--DLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEE 240
            QE  LV     P+  D  +   E  +   E + + +A +EE  +   +E  K   A E+ 
Sbjct: 1444 QEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGEKL 1503

Query: 241  SAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAE 285
            S EE   +E        K + E+W +  ++    + KE++ KD E
Sbjct: 1504 SPEEEMLQEDK------KLKWEEWKQVWENMLSSKSKEQQYKDEE 1542



 Score = 30.4 bits (67), Expect = 1.9
 Identities = 28/105 (26%), Positives = 51/105 (48%), Gaps = 5/105 (4%)

Query: 187  LVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPA 246
            L PE E+  +  ++  E  ++  E   + ++ E++  +E  E   +EE + E E  E+  
Sbjct: 1503 LSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEE-EVTLEEEVSREGEEKEQQV 1561

Query: 247  TEEAAAPEEVTKYQ--HEKWDEEAQDAAGKEEK--EEKEKDAENK 287
            TEE    +E  K+   H K     +  A +E K  +E+EK A+ +
Sbjct: 1562 TEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEE 1606



 Score = 29.6 bits (65), Expect = 3.3
 Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 6/97 (6%)

Query: 198  AEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAPEEVT 257
            A+  R+ A+E  EEK  +E  E +LA+E  +         +++     A  + A  EE  
Sbjct: 1589 AQEERKLAQE--EEKLAQE--ERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETL 1644

Query: 258  KYQHEKWDEEAQDAAGKEEKEEK--EKDAENKVKNSK 292
              + EK  +EA+  A K +K  K  EK A  + K +K
Sbjct: 1645 AQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAK 1681



 Score = 29.3 bits (64), Expect = 4.3
 Identities = 33/109 (30%), Positives = 50/109 (45%), Gaps = 6/109 (5%)

Query: 183  QEAALVPE-PEVPADLAEMAREPAEEPAEE-KPTEEAAEEELAEEAAEEPAKEEPAAEEE 240
            QE  L  E  E+  D+ E++ +  E   EE K  EE  +++LAEE      + E  +EEE
Sbjct: 1710 QEKELAQELEELEWDMEELSWKEEELNQEEGKLVEE--KKKLAEEEEALAWQREKLSEEE 1767

Query: 241  SAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEK--EEKEKDAENK 287
            +      E     +E      EK  EE +    K E+  E+K K A+ +
Sbjct: 1768 TKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKR 1816


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 41/120 (34%), Positives = 56/120 (46%), Gaps = 10/120 (8%)

Query: 174 PEGEGLGLLQEAALVPE--------PEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEE 225
           P   G   L    LVPE        P +  DL  +    ++E  EE+  EE  EEE  EE
Sbjct: 847 PPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEE--EEEEEEE 904

Query: 226 AAEEPAKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAE 285
             EE  +EE   EEE  EE   EE    EE  + + E  +EE ++   +EE+ E+ +D E
Sbjct: 905 EEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLE 964



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 28/74 (37%), Positives = 44/74 (59%), Gaps = 5/74 (6%)

Query: 214 TEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAG 273
           ++E  EEE  EE  EE  +EE   EE+  EE   EE    EE  + + E+++EE ++  G
Sbjct: 886 SDEEEEEEEEEEEEEEEEEEE---EEDFEEEEEDEEEYFEEE--EEEEEEFEEEFEEEEG 940

Query: 274 KEEKEEKEKDAENK 287
           + E+EE+E+D E +
Sbjct: 941 ELEEEEEEEDEEEE 954



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 59/233 (25%), Positives = 81/233 (34%), Gaps = 29/233 (12%)

Query: 73   NAEEDSEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGFRMEFLDMVHSLLLRIYHND 132
            N+ ++ E    EEEEEEEEE  E ++F+               E  +             
Sbjct: 884  NSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEF-------- 935

Query: 133  HILIRMRGGRLMRRRRTAAPSGSEEPRLLLVHERLGVGAAGPEGEGLGLLQEAALVPEPE 192
                    G L            EE   L   E L  G AG E E  G      L P   
Sbjct: 936  ----EEEEGELEEEEEE---EDEEEEEELEEVEDLEFGTAGGEVEE-GAPPPPTLPPALP 987

Query: 193  VPADLAEMAREPAEEPA-----EEKPTEEAAEEELAEEAAEE--PAKEEPAAEEESA--- 242
             P    ++  EP  EP      EE  TEE    + A   A E  P++ E   E ES    
Sbjct: 988  PPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAG 1047

Query: 243  ---EEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVKNSK 292
               +E   EE +AP  + + + E   ++ Q       +EE E + E +    K
Sbjct: 1048 PPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEK 1100



 Score = 37.7 bits (86), Expect = 0.012
 Identities = 40/113 (35%), Positives = 48/113 (42%), Gaps = 12/113 (10%)

Query: 174 PEGEGLGLLQEAALV----PEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEE 229
           P G G   L+E   V       E   +  E   E  EE  EE+  EE  EEE  EE  EE
Sbjct: 866 PGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEE--EEEDEEEYFEE 923

Query: 230 PAKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQD----AAGKEEKE 278
             +EE   EEE  EE    E    EE  + + E   EE +D     AG E +E
Sbjct: 924 EEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEEL--EEVEDLEFGTAGGEVEE 974



 Score = 34.7 bits (78), Expect = 0.10
 Identities = 59/208 (28%), Positives = 75/208 (36%), Gaps = 40/208 (19%)

Query: 56   EEEGEQAAGLAAAPGGGNAEEDSEIRIVEEEEEEEEERNEADNFDLVAAARRYPIRGFRM 115
            EEE E+          G  EE+ E    EE+EEEEEE  E ++ +   A       G   
Sbjct: 924  EEEEEEEFEEEFEEEEGELEEEEE----EEDEEEEEELEEVEDLEFGTAG------GEVE 973

Query: 116  EFLDMVHSLLLRIYHNDHILIRMRGGRLMRRRRTAAPSGSEEPRLLLVHERLGVGAAGPE 175
            E      +L   +   +                   P    EP LLL  E  G      E
Sbjct: 974  EGAPPPPTLPPALPPPE-------------SPPKVQPEPEPEPGLLLEVEEPGT----EE 1016

Query: 176  GEGLGLLQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEE-------LAEEAAE 228
              G     + A    PE      E+ RE  E PA   P +E  EEE       L EE  +
Sbjct: 1017 ERG----ADTAPTLAPEALPSQGEVERE-GESPAAGPPPQELVEEEPSAPPTLLEEETED 1071

Query: 229  EPAKEEPAAEEESAEEPATE-EAAAPEE 255
               K +P  E  + EE  TE EA A +E
Sbjct: 1072 GSDKVQPPPETPAEEEMETETEAEALQE 1099



 Score = 29.6 bits (65), Expect = 3.3
 Identities = 33/118 (27%), Positives = 41/118 (34%), Gaps = 9/118 (7%)

Query: 152  PSGSEEPRLLLVHERLGVGAAGPEGEGLGLLQEAALVPEPEVPADLAEMAREPAEEPAEE 211
            P    EP LLL  E  G      E  G     + A    PE      E+ RE     A  
Sbjct: 997  PEPEPEPGLLLEVEEPGT----EEERGA----DTAPTLAPEALPSQGEVEREGESPAAGP 1048

Query: 212  KPTEEAAEEELAEEA-AEEPAKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEA 268
             P E   EE  A     EE  ++     +   E PA EE     E    Q ++ D+ A
Sbjct: 1049 PPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDDTA 1106


>gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo
           sapiens]
          Length = 525

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 38/105 (36%), Positives = 52/105 (49%), Gaps = 8/105 (7%)

Query: 192 EVPADLAEMAREPAEE--PAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEE-SAEEPATE 248
           ++PA  A    EP EE  P    PTEE  EEE  EE  EE  +EE   + E   E+P   
Sbjct: 288 DLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEE--EEEEEEAEEEEEEEDSEVQGEQPKPA 345

Query: 249 EAAAPEEVTKY--QHEKWDEEAQDAAGK-EEKEEKEKDAENKVKN 290
             A  +++  Y  Q + + + AQ+A  K EE E   KD E  ++N
Sbjct: 346 SPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRN 390



 Score = 34.3 bits (77), Expect = 0.13
 Identities = 27/95 (28%), Positives = 41/95 (43%)

Query: 190 EPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEE 249
           E E    +AE+ RE            + A EE  ++  E  A ++   ++        EE
Sbjct: 123 ERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEE 182

Query: 250 AAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDA 284
           A  PE   K QH+K  EE   AA  ++++E   DA
Sbjct: 183 AEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADA 217



 Score = 30.8 bits (68), Expect = 1.5
 Identities = 16/58 (27%), Positives = 30/58 (51%), Gaps = 6/58 (10%)

Query: 235 PAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVKNSK 292
           PA       EP  E+   P   T+ + E+ +EE      +EE EE+E++ +++V+  +
Sbjct: 290 PAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEE------EEEAEEEEEEEDSEVQGEQ 341


>gi|21361639 DIPB protein [Homo sapiens]
          Length = 344

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 7/96 (7%)

Query: 194 PADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAP 253
           PAD     +E AE   E+       E E+  EA EE   EE +  EE +E     E  + 
Sbjct: 70  PADGEGAGKEEAEVKVEQ-------EREIESEAGEESESEEESESEEESETEEESEDESD 122

Query: 254 EEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVK 289
           EE  +   E+ ++E +  A ++ +EE E +AE + +
Sbjct: 123 EESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETE 158



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 2/107 (1%)

Query: 175 EGEGLGLLQ-EAALVPEPEVPADLAEMAREPAE-EPAEEKPTEEAAEEELAEEAAEEPAK 232
           +GEG G  + E  +  E E+ ++  E +    E E  EE  TEE +E+E  EE+ E+  +
Sbjct: 72  DGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEE 131

Query: 233 EEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEE 279
           E    +E  AEE   EE  +  E       ++D E +  A +  K +
Sbjct: 132 EMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRK 178



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 36/122 (29%), Positives = 48/122 (39%), Gaps = 8/122 (6%)

Query: 168 GVGAAGPEGEGLGLLQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAA 227
           G  A  P  +G G  +E A V          E  RE   E  EE  +EE +E E   E  
Sbjct: 63  GSQAWTPPADGEGAGKEEAEVK--------VEQEREIESEAGEESESEEESESEEESETE 114

Query: 228 EEPAKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENK 287
           EE   E     EE +EE   +E  +  E    +  + + E +  A  E   E E +AE  
Sbjct: 115 EESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERV 174

Query: 288 VK 289
            K
Sbjct: 175 AK 176



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 37/137 (27%), Positives = 60/137 (43%), Gaps = 21/137 (15%)

Query: 168 GVGAAGPEGEGLGLLQEAALVPEPEVPADLAEMARE--------PAEEPAEEKPTEEAAE 219
           GVGAA  E    G   E     EP+      E+ RE         AE   ++  +   AE
Sbjct: 4   GVGAAFEELPHDGTCDEC----EPDEAPGAEEVCRECGFCYCRRHAEAHRQKFLSHHLAE 59

Query: 220 EELAEEAAEEPAKEEPAAEEES---------AEEPATEEAAAPEEVTKYQHEKWDEEAQD 270
                +A   PA  E A +EE+          E  A EE+ + EE    +  + +EE++D
Sbjct: 60  YVHGSQAWTPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESED 119

Query: 271 AAGKEEKEEKEKDAENK 287
            + +E +E+ E++ E++
Sbjct: 120 ESDEESEEDSEEEMEDE 136



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 24/80 (30%), Positives = 42/80 (52%), Gaps = 1/80 (1%)

Query: 214 TEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAG 273
           T  A  E   +E AE   ++E   E E+ EE  +EE +  EE ++ + E  DE  +++  
Sbjct: 68  TPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEE 127

Query: 274 KEEKE-EKEKDAENKVKNSK 292
             E+E E E+++E +  N +
Sbjct: 128 DSEEEMEDEQESEAEEDNQE 147



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 30/96 (31%), Positives = 47/96 (48%), Gaps = 9/96 (9%)

Query: 153 SGSEEPRLLLVHERLGVGAAGPEGEGLGLLQEAALVPEPEVPADLAEMAREPAEEPAEEK 212
           +G EE  + +  ER     AG E E     +E +   E E  ++  E + + ++E +EE 
Sbjct: 76  AGKEEAEVKVEQEREIESEAGEESES----EEES---ESEEESETEEESEDESDEESEED 128

Query: 213 PTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATE 248
            +EE  E+E  E  AEE  +EE  +E E   E  +E
Sbjct: 129 -SEEEMEDE-QESEAEEDNQEEGESEAEGETEAESE 162


>gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo
           sapiens]
          Length = 1782

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 66/291 (22%), Positives = 121/291 (41%), Gaps = 40/291 (13%)

Query: 42  NTVAGVAGPMRGLGEEEGEQAAGLAAAPGGG--NAEEDSEIRIVEEEEEEEEERNEADNF 99
           +T+ GVA     L  +EG+      A  G G  N++E+ E+ + E  + + E+ ++ D+ 
Sbjct: 63  STINGVA-EQDELSLQEGDLNGQKGALNGQGALNSQEEEEVIVTEVGQRDSEDVSKRDS- 120

Query: 100 DLVAAARRYPIRGFRMEFLDMVHSLLLRIYHNDHILIRM--------------RGGRLMR 145
           D   A +   +     +  +    ++ +I  ++  L  +              +  + + 
Sbjct: 121 DKEMATKSAVVHDITDDGQEETPEIIEQIPSSESNLEELTQPTESQANDIGFKKVFKFVG 180

Query: 146 RRRTAAPSGSEEP---RLLLVHERLGVGAAGP---EGEGLGLLQEAALVPEPEVPADLAE 199
            + T     +E+P   +LL V +  G GAAG    +   LG  + A+   EP+   +  E
Sbjct: 181 FKFTVKKDKTEKPDTVQLLTVKKDEGEGAAGAGDHKDPSLGAGEAASKESEPKQSTEKPE 240

Query: 200 MAREPAEEPAEEKPTEEAAEE-ELAEEAAEEPAKEEPAAEEESAEEPATEEA-------- 250
              +  +  AE  P  E+ +  E  +E  EE  ++EP+   ES   P T E         
Sbjct: 241 ETLKREQSHAEISPPAESGQAVEECKEEGEEKQEKEPSKSAESPTSPVTSETGSTFKKFF 300

Query: 251 ----AAPEEVTKYQHEKWDEEAQDAAGKEEKEEK---EKDAENKVKNSKGT 294
               A   + T ++  K DE       KE++ EK   E+D + +V + K T
Sbjct: 301 TQGWAGWRKKTSFRKPKEDEVEASEKKKEQEPEKVDTEEDGKAEVASEKLT 351



 Score = 34.3 bits (77), Expect = 0.13
 Identities = 27/97 (27%), Positives = 40/97 (41%), Gaps = 2/97 (2%)

Query: 175  EGEGLGLLQEAALVPEPEVPADLAEM--AREPAEEPAEEKPTEEAAEEELAEEAAEEPAK 232
            E  G  ++ EA L PE    A+ A    A E  E  A E+ TE  +      ++ +   +
Sbjct: 959  EARGDTVVSEAELTPEAVTAAETAGPLGAEEGTEASAAEETTEMVSAVSQLTDSPDTTEE 1018

Query: 233  EEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQ 269
              P  E E       E+    +EV +   EK  EE+Q
Sbjct: 1019 ATPVQEVEGGVPDIEEQERRTQEVLQAVAEKVKEESQ 1055



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 13/103 (12%)

Query: 190 EPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEE 249
           E EV A   +  +EP +   EE    E A E+L   A+E+   +EPA   ESA EP    
Sbjct: 318 EDEVEASEKKKEQEPEKVDTEEDGKAEVASEKLT--ASEQAHPQEPA---ESAHEPRLS- 371

Query: 250 AAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVKNSK 292
                   +Y+  +   E Q +  +   EEK      +V + K
Sbjct: 372 -------AEYEKVELPSEEQVSGSQGPSEEKPAPLATEVFDEK 407



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 37/142 (26%), Positives = 58/142 (40%), Gaps = 10/142 (7%)

Query: 147 RRTAAPSGSEEPRLLLVHERLGVGAAGPEGEGLGLLQEAALVPEPEVPADLAEMAREPAE 206
           RR   P G +E        +  V  AGP G         A+VP  E  A   E       
Sbjct: 814 RRKKRPDGKQE--------QAPVEDAGPTGANEDDSDVPAVVPLSEYDAVEREKMEAQQA 865

Query: 207 EPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDE 266
           + + E+P ++AA  E+++E +E       AA  +        E  +P  ++    E  ++
Sbjct: 866 QKSAEQPEQKAA-TEVSKELSESQVHMMAAAVADGTRAATIIEERSPSWISASVTEPLEQ 924

Query: 267 -EAQDAAGKEEKEEKEKDAENK 287
            EA+ A   EE  E+E  AE +
Sbjct: 925 VEAEAALLTEEVLEREVIAEEE 946



 Score = 32.7 bits (73), Expect = 0.39
 Identities = 31/101 (30%), Positives = 42/101 (41%), Gaps = 7/101 (6%)

Query: 185  AALVPEPEVPADLAEMAREPAEEPAEEKP--TEEAAEEELAEEAAEEPAKEEPAAEEESA 242
            AA + E   P+ ++    EP E+   E    TEE  E E+  E  E P   EP  E   A
Sbjct: 902  AATIIEERSPSWISASVTEPLEQVEAEAALLTEEVLEREVIAEE-EPPTVTEPLPENREA 960

Query: 243  --EEPATEEAAAPEEVTKYQ--HEKWDEEAQDAAGKEEKEE 279
              +   +E    PE VT  +       EE  +A+  EE  E
Sbjct: 961  RGDTVVSEAELTPEAVTAAETAGPLGAEEGTEASAAEETTE 1001



 Score = 32.3 bits (72), Expect = 0.51
 Identities = 31/117 (26%), Positives = 47/117 (40%), Gaps = 6/117 (5%)

Query: 175  EGEGLGLLQEAALVPEPEVPADLAEMAREPAEEPAEEKPTEEAAEEELAEEA-AEEPAKE 233
            EG G G       VPE +  A LAE   +   EP E++  ++  + E    A A+  A  
Sbjct: 1666 EGGGAGTKS----VPEDDGHALLAERIEKSLVEPKEDEKGDDVDDPENQNSALADTDASG 1721

Query: 234  EPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDAAGKEEKEEKEKDAENKVKN 290
                E      P  +E    +EV + Q  K   E+  A   + +EE +K      K+
Sbjct: 1722 GLTKESPDTNGPKQKEKEDAQEV-ELQEGKVHSESDKAITPQAQEELQKQERESAKS 1777



 Score = 30.4 bits (67), Expect = 1.9
 Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 8/82 (9%)

Query: 212 KPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAPEEVTKYQHEKWDEEAQDA 271
           K  E  A E+  E+  E+   EE    E ++E+    E A P+E          E A + 
Sbjct: 317 KEDEVEASEKKKEQEPEKVDTEEDGKAEVASEKLTASEQAHPQEPA--------ESAHEP 368

Query: 272 AGKEEKEEKEKDAENKVKNSKG 293
               E E+ E  +E +V  S+G
Sbjct: 369 RLSAEYEKVELPSEEQVSGSQG 390


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.302    0.125    0.337 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,645,605
Number of Sequences: 37866
Number of extensions: 831483
Number of successful extensions: 24986
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 700
Number of HSP's successfully gapped in prelim test: 743
Number of HSP's that attempted gapping in prelim test: 7411
Number of HSP's gapped (non-prelim): 10237
length of query: 294
length of database: 18,247,518
effective HSP length: 101
effective length of query: 193
effective length of database: 14,423,052
effective search space: 2783649036
effective search space used: 2783649036
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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