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Search of human proteins with 116812616
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116812616 RecQ protein-like 4 [Homo sapiens]
(1208 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116812616 RecQ protein-like 4 [Homo sapiens] 2477 0.0
gi|148612816 RecQ protein-like 5 isoform 1 [Homo sapiens] 183 1e-45
gi|51242943 RecQ protein-like 5 isoform 3 [Homo sapiens] 183 1e-45
gi|51242947 RecQ protein-like 5 isoform 2 [Homo sapiens] 183 1e-45
gi|4557365 Bloom syndrome protein [Homo sapiens] 171 4e-42
gi|14591902 RecQ protein-like [Homo sapiens] 170 9e-42
gi|14591904 RecQ protein-like [Homo sapiens] 170 9e-42
gi|110735439 Werner syndrome protein [Homo sapiens] 167 7e-41
gi|169218196 PREDICTED: similar to Werner syndrome ATP-dependent... 167 7e-41
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap... 80 1e-14
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 72 4e-12
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] 68 6e-11
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] 68 6e-11
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] 66 2e-10
gi|21071032 DEAD-box protein abstrakt [Homo sapiens] 64 7e-10
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi... 60 1e-08
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s... 59 3e-08
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap... 58 6e-08
gi|13129006 nucleolar protein GU2 [Homo sapiens] 58 6e-08
gi|7661920 eukaryotic translation initiation factor 4A, isoform ... 57 1e-07
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap... 56 2e-07
gi|4503529 eukaryotic translation initiation factor 4A isoform 1... 55 3e-07
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi... 55 5e-07
gi|19924099 synapsin I isoform Ia [Homo sapiens] 54 7e-07
gi|19924097 synapsin I isoform Ib [Homo sapiens] 54 7e-07
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ... 53 2e-06
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [... 53 2e-06
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ... 53 2e-06
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi... 52 3e-06
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ... 52 4e-06
>gi|116812616 RecQ protein-like 4 [Homo sapiens]
Length = 1208
Score = 2477 bits (6421), Expect = 0.0
Identities = 1208/1208 (100%), Positives = 1208/1208 (100%)
Query: 1 MERLRDVRERLQAWERAFRRQRGRRPSQDDVEAAPEETRALYREYRTLKRTTGQAGGGLR 60
MERLRDVRERLQAWERAFRRQRGRRPSQDDVEAAPEETRALYREYRTLKRTTGQAGGGLR
Sbjct: 1 MERLRDVRERLQAWERAFRRQRGRRPSQDDVEAAPEETRALYREYRTLKRTTGQAGGGLR 60
Query: 61 SSESLPAAAEEAPEPRCWGPHLNRAATKSPQSTPGRSRQGSVPDYGQRLKANLKGTLQAG 120
SSESLPAAAEEAPEPRCWGPHLNRAATKSPQSTPGRSRQGSVPDYGQRLKANLKGTLQAG
Sbjct: 61 SSESLPAAAEEAPEPRCWGPHLNRAATKSPQSTPGRSRQGSVPDYGQRLKANLKGTLQAG 120
Query: 121 PALGRRPWPLGRASSKASTPKPPGTGPVPSFAEKVSDEPPQLPEPQPRPGRLQHLQASLS 180
PALGRRPWPLGRASSKASTPKPPGTGPVPSFAEKVSDEPPQLPEPQPRPGRLQHLQASLS
Sbjct: 121 PALGRRPWPLGRASSKASTPKPPGTGPVPSFAEKVSDEPPQLPEPQPRPGRLQHLQASLS 180
Query: 181 QRLGSLDPGWLQRCHSEVPDFLGAPKACRPDLGSEESQLLIPGESAVLGPGAGSQGPEAS 240
QRLGSLDPGWLQRCHSEVPDFLGAPKACRPDLGSEESQLLIPGESAVLGPGAGSQGPEAS
Sbjct: 181 QRLGSLDPGWLQRCHSEVPDFLGAPKACRPDLGSEESQLLIPGESAVLGPGAGSQGPEAS 240
Query: 241 AFQEVSIRVGSPQPSSSGGEKRRWNEEPWESPAQVQQESSQAGPPSEGAGAVAVEEDPPG 300
AFQEVSIRVGSPQPSSSGGEKRRWNEEPWESPAQVQQESSQAGPPSEGAGAVAVEEDPPG
Sbjct: 241 AFQEVSIRVGSPQPSSSGGEKRRWNEEPWESPAQVQQESSQAGPPSEGAGAVAVEEDPPG 300
Query: 301 EPVQAQPPQPCSSPSNPRYHGLSPSSQARAGKAEGTAPLHIFPRLARHDRGNYVRLNMKQ 360
EPVQAQPPQPCSSPSNPRYHGLSPSSQARAGKAEGTAPLHIFPRLARHDRGNYVRLNMKQ
Sbjct: 301 EPVQAQPPQPCSSPSNPRYHGLSPSSQARAGKAEGTAPLHIFPRLARHDRGNYVRLNMKQ 360
Query: 361 KHYVRGRALRSRLLRKQAWKQKWRKKGECFGGGGATVTTKESCFLNEQFDHWAAQCPRPA 420
KHYVRGRALRSRLLRKQAWKQKWRKKGECFGGGGATVTTKESCFLNEQFDHWAAQCPRPA
Sbjct: 361 KHYVRGRALRSRLLRKQAWKQKWRKKGECFGGGGATVTTKESCFLNEQFDHWAAQCPRPA 420
Query: 421 SEEDTDAVGPEPLVPSPQPVPEVPSLDPTVLPLYSLGPSGQLAETPAEVFQALEQLGHQA 480
SEEDTDAVGPEPLVPSPQPVPEVPSLDPTVLPLYSLGPSGQLAETPAEVFQALEQLGHQA
Sbjct: 421 SEEDTDAVGPEPLVPSPQPVPEVPSLDPTVLPLYSLGPSGQLAETPAEVFQALEQLGHQA 480
Query: 481 FRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPALLYSRRSPCLTLVVSPLLSLMDDQ 540
FRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPALLYSRRSPCLTLVVSPLLSLMDDQ
Sbjct: 481 FRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPALLYSRRSPCLTLVVSPLLSLMDDQ 540
Query: 541 VSGLPPCLKAACIHSGMTRKQRESVLQKIRAAQVHVLMLTPEALVGAGGLPPAAQLPPVA 600
VSGLPPCLKAACIHSGMTRKQRESVLQKIRAAQVHVLMLTPEALVGAGGLPPAAQLPPVA
Sbjct: 541 VSGLPPCLKAACIHSGMTRKQRESVLQKIRAAQVHVLMLTPEALVGAGGLPPAAQLPPVA 600
Query: 601 FACIDEAHCLSQWSHNFRPCYLRVCKVLRERMGVHCFLGLTATATRRTASDVAQHLAVAE 660
FACIDEAHCLSQWSHNFRPCYLRVCKVLRERMGVHCFLGLTATATRRTASDVAQHLAVAE
Sbjct: 601 FACIDEAHCLSQWSHNFRPCYLRVCKVLRERMGVHCFLGLTATATRRTASDVAQHLAVAE 660
Query: 661 EPDLHGPAPVPTNLHLSVSMDRDTDQALLTLLQGKRFQNLDSIIIYCNRREDTERIAALL 720
EPDLHGPAPVPTNLHLSVSMDRDTDQALLTLLQGKRFQNLDSIIIYCNRREDTERIAALL
Sbjct: 661 EPDLHGPAPVPTNLHLSVSMDRDTDQALLTLLQGKRFQNLDSIIIYCNRREDTERIAALL 720
Query: 721 RTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDR 780
RTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDR
Sbjct: 721 RTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDR 780
Query: 781 PDVRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVHADSTDFL 840
PDVRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVHADSTDFL
Sbjct: 781 PDVRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVHADSTDFL 840
Query: 841 AVKRLVQRVFPACTCTCTRPPSEQEGAVGGERPVPKYPPQEAEQLSHQAAPGPRRVCMGH 900
AVKRLVQRVFPACTCTCTRPPSEQEGAVGGERPVPKYPPQEAEQLSHQAAPGPRRVCMGH
Sbjct: 841 AVKRLVQRVFPACTCTCTRPPSEQEGAVGGERPVPKYPPQEAEQLSHQAAPGPRRVCMGH 900
Query: 901 ERALPIQLTVQALDMPEEAIETLLCYLELHPHHWLELLATTYTHCRLNCPGGPAQLQALA 960
ERALPIQLTVQALDMPEEAIETLLCYLELHPHHWLELLATTYTHCRLNCPGGPAQLQALA
Sbjct: 901 ERALPIQLTVQALDMPEEAIETLLCYLELHPHHWLELLATTYTHCRLNCPGGPAQLQALA 960
Query: 961 HRCPPLAVCLAQQLPEDPGQGSSSVEFDMVKLVDSMGWELASVRRALCQLQWDHEPRTGV 1020
HRCPPLAVCLAQQLPEDPGQGSSSVEFDMVKLVDSMGWELASVRRALCQLQWDHEPRTGV
Sbjct: 961 HRCPPLAVCLAQQLPEDPGQGSSSVEFDMVKLVDSMGWELASVRRALCQLQWDHEPRTGV 1020
Query: 1021 RRGTGVLVEFSELAFHLRSPGDLTAEEKDQICDFLYGRVQARERQALARLRRTFQAFHSV 1080
RRGTGVLVEFSELAFHLRSPGDLTAEEKDQICDFLYGRVQARERQALARLRRTFQAFHSV
Sbjct: 1021 RRGTGVLVEFSELAFHLRSPGDLTAEEKDQICDFLYGRVQARERQALARLRRTFQAFHSV 1080
Query: 1081 AFPSCGPCLEQQDEERSTRLKDLLGRYFEEEEGQEPGGMEDAQGPEPGQARLQDWEDQVR 1140
AFPSCGPCLEQQDEERSTRLKDLLGRYFEEEEGQEPGGMEDAQGPEPGQARLQDWEDQVR
Sbjct: 1081 AFPSCGPCLEQQDEERSTRLKDLLGRYFEEEEGQEPGGMEDAQGPEPGQARLQDWEDQVR 1140
Query: 1141 CDIRQFLSLRPEEKFSSRAVARIFHGIGSPCYPAQVYGQDRRFWRKYLHLSFHALVGLAT 1200
CDIRQFLSLRPEEKFSSRAVARIFHGIGSPCYPAQVYGQDRRFWRKYLHLSFHALVGLAT
Sbjct: 1141 CDIRQFLSLRPEEKFSSRAVARIFHGIGSPCYPAQVYGQDRRFWRKYLHLSFHALVGLAT 1200
Query: 1201 EELLQVAR 1208
EELLQVAR
Sbjct: 1201 EELLQVAR 1208
>gi|148612816 RecQ protein-like 5 isoform 1 [Homo sapiens]
Length = 991
Score = 183 bits (464), Expect = 1e-45
Identities = 137/421 (32%), Positives = 208/421 (49%), Gaps = 53/421 (12%)
Query: 454 YSLGPSGQLAETPAEVFQALEQLGHQAFR-PGQERAVMRILSGISTLLV-LPTGAGKSLC 511
+ P ++ T +VF G +F+ P QE A M ++ G + V +PTGAGKSLC
Sbjct: 8 FPFDPERRVRSTLKKVF------GFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLC 61
Query: 512 YQLPALLYSRRSPCLTLVVSPLLSLMDDQVSGLPPC-LKAACIHSGMTRKQRESVLQKIR 570
YQLPALL + +T+VVSPL++L+ DQV L ++ + ++S ++ ++R+ +L +
Sbjct: 62 YQLPALL----AKGITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLE 117
Query: 571 AA--QVHVLMLTPEALVGAGGLPPAAQLPP---VAFACIDEAHCLSQWSHNFRPCYLRVC 625
Q +L +TPE + P L +++ +DEAHC+SQW H+FRP YLR+
Sbjct: 118 REKPQTKILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRL- 176
Query: 626 KVLRERMGVHCFLGLTATATRRTASDVAQHLAVAEEPDLHGPAPVPTNLHLSVSMDR--- 682
LR R+G + LTATAT + DV L + + + NL V
Sbjct: 177 GALRSRLGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELIS 236
Query: 683 ----DTDQALLTLLQGKRFQNLDSI-IIYCNRREDTERIAALLRTCLHAAWVPGSGGRAP 737
+ L L + + L I+YC RE E++A L
Sbjct: 237 DPYGNLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELS--------------CR 282
Query: 738 KTTAEAYHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFES 797
A+AYHAG+ + ER VQ +M+ ++ V+VAT++FGMG+D+ +VR V H + S
Sbjct: 283 GVNAKAYHAGLKASERTLVQNDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAG 342
Query: 798 YVQAVGRAGRDGQPAHCHLFLQPQGED------------LRELRRHVHADSTDFLAVKRL 845
Y Q GRAGRDG+P+ C L+ D L+E R + +D +A L
Sbjct: 343 YYQESGRAGRDGKPSWCRLYYSRNDRDQVSFLIRKEVAKLQEKRGNKASDKATIMAFDAL 402
Query: 846 V 846
V
Sbjct: 403 V 403
>gi|51242943 RecQ protein-like 5 isoform 3 [Homo sapiens]
Length = 410
Score = 183 bits (464), Expect = 1e-45
Identities = 137/421 (32%), Positives = 208/421 (49%), Gaps = 53/421 (12%)
Query: 454 YSLGPSGQLAETPAEVFQALEQLGHQAFR-PGQERAVMRILSGISTLLV-LPTGAGKSLC 511
+ P ++ T +VF G +F+ P QE A M ++ G + V +PTGAGKSLC
Sbjct: 8 FPFDPERRVRSTLKKVF------GFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLC 61
Query: 512 YQLPALLYSRRSPCLTLVVSPLLSLMDDQVSGLPPC-LKAACIHSGMTRKQRESVLQKIR 570
YQLPALL + +T+VVSPL++L+ DQV L ++ + ++S ++ ++R+ +L +
Sbjct: 62 YQLPALL----AKGITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLE 117
Query: 571 AA--QVHVLMLTPEALVGAGGLPPAAQLPP---VAFACIDEAHCLSQWSHNFRPCYLRVC 625
Q +L +TPE + P L +++ +DEAHC+SQW H+FRP YLR+
Sbjct: 118 REKPQTKILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRL- 176
Query: 626 KVLRERMGVHCFLGLTATATRRTASDVAQHLAVAEEPDLHGPAPVPTNLHLSVSMDR--- 682
LR R+G + LTATAT + DV L + + + NL V
Sbjct: 177 GALRSRLGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELIS 236
Query: 683 ----DTDQALLTLLQGKRFQNLDSI-IIYCNRREDTERIAALLRTCLHAAWVPGSGGRAP 737
+ L L + + L I+YC RE E++A L
Sbjct: 237 DPYGNLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELS--------------CR 282
Query: 738 KTTAEAYHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFES 797
A+AYHAG+ + ER VQ +M+ ++ V+VAT++FGMG+D+ +VR V H + S
Sbjct: 283 GVNAKAYHAGLKASERTLVQNDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAG 342
Query: 798 YVQAVGRAGRDGQPAHCHLFLQPQGED------------LRELRRHVHADSTDFLAVKRL 845
Y Q GRAGRDG+P+ C L+ D L+E R + +D +A L
Sbjct: 343 YYQESGRAGRDGKPSWCRLYYSRNDRDQVSFLIRKEVAKLQEKRGNKASDKATIMAFDAL 402
Query: 846 V 846
V
Sbjct: 403 V 403
>gi|51242947 RecQ protein-like 5 isoform 2 [Homo sapiens]
Length = 435
Score = 183 bits (464), Expect = 1e-45
Identities = 137/421 (32%), Positives = 208/421 (49%), Gaps = 53/421 (12%)
Query: 454 YSLGPSGQLAETPAEVFQALEQLGHQAFR-PGQERAVMRILSGISTLLV-LPTGAGKSLC 511
+ P ++ T +VF G +F+ P QE A M ++ G + V +PTGAGKSLC
Sbjct: 8 FPFDPERRVRSTLKKVF------GFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLC 61
Query: 512 YQLPALLYSRRSPCLTLVVSPLLSLMDDQVSGLPPC-LKAACIHSGMTRKQRESVLQKIR 570
YQLPALL + +T+VVSPL++L+ DQV L ++ + ++S ++ ++R+ +L +
Sbjct: 62 YQLPALL----AKGITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLE 117
Query: 571 AA--QVHVLMLTPEALVGAGGLPPAAQLPP---VAFACIDEAHCLSQWSHNFRPCYLRVC 625
Q +L +TPE + P L +++ +DEAHC+SQW H+FRP YLR+
Sbjct: 118 REKPQTKILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRL- 176
Query: 626 KVLRERMGVHCFLGLTATATRRTASDVAQHLAVAEEPDLHGPAPVPTNLHLSVSMDR--- 682
LR R+G + LTATAT + DV L + + + NL V
Sbjct: 177 GALRSRLGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELIS 236
Query: 683 ----DTDQALLTLLQGKRFQNLDSI-IIYCNRREDTERIAALLRTCLHAAWVPGSGGRAP 737
+ L L + + L I+YC RE E++A L
Sbjct: 237 DPYGNLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELS--------------CR 282
Query: 738 KTTAEAYHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFES 797
A+AYHAG+ + ER VQ +M+ ++ V+VAT++FGMG+D+ +VR V H + S
Sbjct: 283 GVNAKAYHAGLKASERTLVQNDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAG 342
Query: 798 YVQAVGRAGRDGQPAHCHLFLQPQGED------------LRELRRHVHADSTDFLAVKRL 845
Y Q GRAGRDG+P+ C L+ D L+E R + +D +A L
Sbjct: 343 YYQESGRAGRDGKPSWCRLYYSRNDRDQVSFLIRKEVAKLQEKRGNKASDKATIMAFDAL 402
Query: 846 V 846
V
Sbjct: 403 V 403
>gi|4557365 Bloom syndrome protein [Homo sapiens]
Length = 1417
Score = 171 bits (433), Expect = 4e-42
Identities = 122/352 (34%), Positives = 177/352 (50%), Gaps = 28/352 (7%)
Query: 474 EQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPALLYSRRSPCLTLVVSPL 533
++ G FR Q A+ L G +++PTG GKSLCYQLPA + SP +T+V+SPL
Sbjct: 661 KKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACV----SPGVTVVISPL 716
Query: 534 LSLMDDQVSGLPPC-LKAACIHSGMTRKQRESVLQKIRAAQ--VHVLMLTPEALVGAGGL 590
SL+ DQV L + A + T + ++ ++ + +L +TPE + + L
Sbjct: 717 RSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRL 776
Query: 591 PPAAQ----LPPVAFACIDEAHCLSQWSHNFRPCYLRVCKVLRERMGVHCFLGLTATATR 646
+ +A IDEAHC+SQW H+FR Y R+ +LR++ + LTATA
Sbjct: 777 ISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRM-NMLRQKFPSVPVMALTATANP 835
Query: 647 RTASDVAQHLAVAEEPDLHGPAPVPTNLHLSVSMDRDTDQALLTLLQGKRFQNLDSIIIY 706
R D+ L + P + + NL V + A L ++ DS IIY
Sbjct: 836 RVQKDILTQLKILR-PQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIY 894
Query: 707 CNRREDTERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRERRRVQRAFM-QGQL 765
C R + + +A L+ A AYHAG+ R VQ+ ++ Q
Sbjct: 895 CLSRRECDTMADTLQR--------------DGLAALAYHAGLSDSARDEVQQKWINQDGC 940
Query: 766 RVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLF 817
+V+ AT+AFGMG+D+PDVR V+H LP S E Y Q GRAGRDG+ +HC LF
Sbjct: 941 QVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLF 992
>gi|14591902 RecQ protein-like [Homo sapiens]
Length = 649
Score = 170 bits (430), Expect = 9e-42
Identities = 123/371 (33%), Positives = 194/371 (52%), Gaps = 41/371 (11%)
Query: 459 SGQLAETPAEVFQALEQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPALL 518
SG++ + VF+ + FRP Q + ++G LV+PTG GKSLCYQLPAL
Sbjct: 76 SGKVKDILQNVFKL------EKFRPLQLETINVTMAGKEVFLVMPTGGGKSLCYQLPALC 129
Query: 519 YSRRSPCLTLVVSPLLSLMDDQVSGLPPC-LKAACIHSGMTRKQRESVLQKI--RAAQVH 575
S TLV+ PL+SLM+DQ+ L + A +++ +++ + V ++ + +++
Sbjct: 130 ----SDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNKNSELK 185
Query: 576 VLMLTPEALVGA----GGLPPAAQLPPVAFACIDEAHCLSQWSHNFRPCYLRVCKVLRER 631
++ +TPE + + L A + +DE HC SQW H+FRP Y + +L+ +
Sbjct: 186 LIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDY-KALGILKRQ 244
Query: 632 MGVHCFLGLTATATRRTASDVAQHLAVAEEPDLHGPAPVPTNLHLSV----SMDRDTDQA 687
+GLTATAT +D AQ + E+ + NL+ V S D +
Sbjct: 245 FPNASLIGLTATATNHVLTD-AQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDFIED 303
Query: 688 LLTLLQGKRFQNLDSIIIYCNRREDTERIAALLRTC-LHAAWVPGSGGRAPKTTAEAYHA 746
++ L+ G R++ S IIYC ++D+E++ L+ +HA AYHA
Sbjct: 304 IVKLING-RYKG-QSGIIYCFSQKDSEQVTVSLQNLGIHAG---------------AYHA 346
Query: 747 GMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAG 806
+ ++ V R + +++VVVATVAFGMG+D+PDVR V+H + S E+Y Q GRAG
Sbjct: 347 NLEPEDKTTVHRKWSANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAG 406
Query: 807 RDGQPAHCHLF 817
RD A C L+
Sbjct: 407 RDDMKADCILY 417
>gi|14591904 RecQ protein-like [Homo sapiens]
Length = 649
Score = 170 bits (430), Expect = 9e-42
Identities = 123/371 (33%), Positives = 194/371 (52%), Gaps = 41/371 (11%)
Query: 459 SGQLAETPAEVFQALEQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPALL 518
SG++ + VF+ + FRP Q + ++G LV+PTG GKSLCYQLPAL
Sbjct: 76 SGKVKDILQNVFKL------EKFRPLQLETINVTMAGKEVFLVMPTGGGKSLCYQLPALC 129
Query: 519 YSRRSPCLTLVVSPLLSLMDDQVSGLPPC-LKAACIHSGMTRKQRESVLQKI--RAAQVH 575
S TLV+ PL+SLM+DQ+ L + A +++ +++ + V ++ + +++
Sbjct: 130 ----SDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNKNSELK 185
Query: 576 VLMLTPEALVGA----GGLPPAAQLPPVAFACIDEAHCLSQWSHNFRPCYLRVCKVLRER 631
++ +TPE + + L A + +DE HC SQW H+FRP Y + +L+ +
Sbjct: 186 LIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDY-KALGILKRQ 244
Query: 632 MGVHCFLGLTATATRRTASDVAQHLAVAEEPDLHGPAPVPTNLHLSV----SMDRDTDQA 687
+GLTATAT +D AQ + E+ + NL+ V S D +
Sbjct: 245 FPNASLIGLTATATNHVLTD-AQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDFIED 303
Query: 688 LLTLLQGKRFQNLDSIIIYCNRREDTERIAALLRTC-LHAAWVPGSGGRAPKTTAEAYHA 746
++ L+ G R++ S IIYC ++D+E++ L+ +HA AYHA
Sbjct: 304 IVKLING-RYKG-QSGIIYCFSQKDSEQVTVSLQNLGIHAG---------------AYHA 346
Query: 747 GMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAG 806
+ ++ V R + +++VVVATVAFGMG+D+PDVR V+H + S E+Y Q GRAG
Sbjct: 347 NLEPEDKTTVHRKWSANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAG 406
Query: 807 RDGQPAHCHLF 817
RD A C L+
Sbjct: 407 RDDMKADCILY 417
>gi|110735439 Werner syndrome protein [Homo sapiens]
Length = 1432
Score = 167 bits (422), Expect = 7e-41
Identities = 110/351 (31%), Positives = 177/351 (50%), Gaps = 32/351 (9%)
Query: 477 GHQAFRPGQERAVMRILSGI-STLLVLPTGAGKSLCYQLPALLYSRRSPCLTLVVSPLLS 535
GH +F+P Q + + +L + V+ TG GKSLC+Q P + + + LV+SPL+S
Sbjct: 545 GHSSFKPVQWKVIHSVLEERRDNVAVMATGYGKSLCFQYPPVYVGK----IGLVISPLIS 600
Query: 536 LMDDQVSGLPPCLKAACIHSGMTRKQRESVLQKIRAAQVHVLMLTPEALVGAGGLPPAAQ 595
LM+DQV L AC + Q E+VL I+ + ++ +TPE G GL +
Sbjct: 601 LMEDQVLQLKMSNIPACF---LGSAQSENVLTDIKLGKYRIVYVTPEYCSGNMGLLQQLE 657
Query: 596 LP-PVAFACIDEAHCLSQWSHNFRPCYLRVCKVLRERMGVHCFLGLTATATRRTASDVAQ 654
+ +DEAHC+S+W H+FR + ++ L+ + + + LTATA+ D+ +
Sbjct: 658 ADIGITLIAVDEAHCISEWGHDFRDSFRKLGS-LKTALPMVPIVALTATASSSIREDIVR 716
Query: 655 HLAVAEEPDLHGPAPVPTNLHLSV-----SMDRDTDQALLTLLQGKRFQNLDSIIIYCNR 709
L + P + NL+L V ++ +D L+ F+ IIYC
Sbjct: 717 CLNL-RNPQITCTGFDRPNLYLEVRRKTGNILQDLQPFLVKTSSHWEFEG--PTIIYCPS 773
Query: 710 REDTERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRERRRVQRAFMQGQLRVVV 769
R+ T+++ LR + YHAGM R+ + F++ +++ V+
Sbjct: 774 RKMTQQVTGELRKL--------------NLSCGTYHAGMSFSTRKDIHHRFVRDEIQCVI 819
Query: 770 ATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQP 820
AT+AFGMG+++ D+R V+H G P ESY Q +GRAGRDG + CH+ P
Sbjct: 820 ATIAFGMGINKADIRQVIHYGAPKDMESYYQEIGRAGRDGLQSSCHVLWAP 870
>gi|169218196 PREDICTED: similar to Werner syndrome ATP-dependent
helicase, partial [Homo sapiens]
Length = 1140
Score = 167 bits (422), Expect = 7e-41
Identities = 110/351 (31%), Positives = 177/351 (50%), Gaps = 32/351 (9%)
Query: 477 GHQAFRPGQERAVMRILSGI-STLLVLPTGAGKSLCYQLPALLYSRRSPCLTLVVSPLLS 535
GH +F+P Q + + +L + V+ TG GKSLC+Q P + + + LV+SPL+S
Sbjct: 253 GHSSFKPVQWKVIHSVLEERRDNVAVMATGYGKSLCFQYPPVYVGK----IGLVISPLIS 308
Query: 536 LMDDQVSGLPPCLKAACIHSGMTRKQRESVLQKIRAAQVHVLMLTPEALVGAGGLPPAAQ 595
LM+DQV L AC + Q E+VL I+ + ++ +TPE G GL +
Sbjct: 309 LMEDQVLQLKMSNIPACF---LGSAQSENVLTDIKLGKYRIVYVTPEYCSGNMGLLQQLE 365
Query: 596 LP-PVAFACIDEAHCLSQWSHNFRPCYLRVCKVLRERMGVHCFLGLTATATRRTASDVAQ 654
+ +DEAHC+S+W H+FR + ++ L+ + + + LTATA+ D+ +
Sbjct: 366 ADIGITLIAVDEAHCISEWGHDFRDSFRKLGS-LKTALPMVPIVALTATASSSIREDIVR 424
Query: 655 HLAVAEEPDLHGPAPVPTNLHLSV-----SMDRDTDQALLTLLQGKRFQNLDSIIIYCNR 709
L + P + NL+L V ++ +D L+ F+ IIYC
Sbjct: 425 CLNL-RNPQITCTGFDRPNLYLEVRRKTGNILQDLQPFLVKTSSHWEFEG--PTIIYCPS 481
Query: 710 REDTERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRERRRVQRAFMQGQLRVVV 769
R+ T+++ LR + YHAGM R+ + F++ +++ V+
Sbjct: 482 RKMTQQVTGELRKL--------------NLSCGTYHAGMSFSTRKDIHHRFVRDEIQCVI 527
Query: 770 ATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQP 820
AT+AFGMG+++ D+R V+H G P ESY Q +GRAGRDG + CH+ P
Sbjct: 528 ATIAFGMGINKADIRQVIHYGAPKDMESYYQEIGRAGRDGLQSSCHVLWAP 578
>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
sapiens]
Length = 648
Score = 80.1 bits (196), Expect = 1e-14
Identities = 83/358 (23%), Positives = 149/358 (41%), Gaps = 41/358 (11%)
Query: 468 EVFQALEQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPALLYSRRSPCLT 527
EV + +++ G Q P Q +A +L GI + V TG GK+LCY +P ++ P L
Sbjct: 252 EVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPSLK 311
Query: 528 --------LVVSPLLSLMDDQVSGLPPC-------LKAACIHSGMTRKQRESVLQKIRAA 572
LV++P L QV G C L++ C++ G R ++ L+K
Sbjct: 312 GQRNRPGMLVLTPTRELAL-QVEG--ECCKYSYKGLRSVCVYGGGNRDEQIEELKK---- 364
Query: 573 QVHVLMLTPEALVGAGGLPPAAQLPPVAFACIDEAHCLSQWSHNFRPCYLRVCKVLRERM 632
V +++ TP L + L + + +DEA + F P +++ +R
Sbjct: 365 GVDIIIATPGRLNDLQ-MSNFVNLKNITYLVLDEADKMLDMG--FEPQIMKILLDVRPDR 421
Query: 633 GVHCFLGLTATATRRTASDVAQHLAVAEEPDLHGPAPVPTNLHLSVSMDRDTDQALLTLL 692
+ R A + + L A ++ V+ + + + T L
Sbjct: 422 QTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFL 481
Query: 693 QGKRFQNLDSIIIYCNRREDTERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRE 752
Q + D +I++ +R+ + +++ L + G+ + E+ H R+
Sbjct: 482 QS--MSSTDKVIVFVSRKAVADHLSSDL--------ILGN------ISVESLHGDREQRD 525
Query: 753 RRRVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQ 810
R + F G++R+++AT GLD DV V + P + E YV +GR GR G+
Sbjct: 526 REKALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGR 583
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 71.6 bits (174), Expect = 4e-12
Identities = 75/365 (20%), Positives = 152/365 (41%), Gaps = 37/365 (10%)
Query: 468 EVFQALEQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPALLYSRRSPCLT 527
++ +L++ G++ P Q +A+ I+SG + + TG+GK++ + LP + L
Sbjct: 382 KILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLE 441
Query: 528 LVVSPLLSLMDDQ----VSGLPPC--------LKAACIHSGMTRKQRESVLQKIRAAQVH 575
P+ +M + C L+ C++ G ++ + L++
Sbjct: 442 EGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKR----GAE 497
Query: 576 VLMLTPEALVG--AGGLPPAAQLPPVAFACIDEAHCLSQWSHNFRPCYLRVCKVLRERMG 633
+++ TP ++ A L V + +DEA + + F P +R+ +R
Sbjct: 498 IIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRM--FDMGFEPQVMRIVDNVRPDRQ 555
Query: 634 VHCFLGLTATATRRTASDVAQHLAVAEEPDLHGPAPVPTNLHLSVSMDRDTDQALLTLLQ 693
F +AT R + + L+ E + G + V +++ V + + + L L
Sbjct: 556 TVMF---SATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLEL 612
Query: 694 GKRFQNLDSIIIYCNRREDTERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRER 753
+Q S+II+ +++E + LL+ + A++ + H G+ +R
Sbjct: 613 LGHYQESGSVIIFVDKQEHAD---GLLKDLMRASY-----------PCMSLHGGIDQYDR 658
Query: 754 RRVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQPAH 813
+ F G +++VAT GLD + V++ P +E YV GR GR G +
Sbjct: 659 DSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGY 718
Query: 814 CHLFL 818
+ F+
Sbjct: 719 AYTFI 723
>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
Length = 731
Score = 67.8 bits (164), Expect = 6e-11
Identities = 80/343 (23%), Positives = 128/343 (37%), Gaps = 39/343 (11%)
Query: 493 LSGISTLLVLPTGAGKSLCYQLPALLYSRRSP---------CLTLVVSPLLSLMDDQVS- 542
LSG + + TG+GK+L Y LPA+++ P CL L + L+ QV+
Sbjct: 206 LSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVAD 265
Query: 543 --GLPPCLKAACIHSGMTRKQRESVLQKIRAAQVHVLMLTPEALVG---AGGLPPAAQLP 597
G LK+ CI+ G + + L++ V + + TP L+ +G L
Sbjct: 266 DYGKCSRLKSTCIYGGAPKGPQIRDLER----GVEICIATPGRLIDFLESG----KTNLR 317
Query: 598 PVAFACIDEAHCLSQWSHNFRPCYLRVCKVLRERMGVHCFLGLTATATRRTASDVAQHLA 657
+ +DEA + F P ++ +R + R+ A D +
Sbjct: 318 RCTYLVLDEADRMLDMG--FEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYT 375
Query: 658 VAEEPDLHGPAPVPTNLHLSVSMDRDTDQALLTLLQGKRFQNLDSIIIYCNRREDTERIA 717
+L A + V M+ + D L+ L++ + + II+ E R
Sbjct: 376 QINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFV---ETKRRCD 432
Query: 718 ALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMG 777
L R W A H ER V F G+ +++AT G
Sbjct: 433 DLTRRMRRDGW-----------PAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRG 481
Query: 778 LDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQP 820
LD DV+ V++ P S E YV +GR R + F P
Sbjct: 482 LDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTP 524
>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
Length = 729
Score = 67.8 bits (164), Expect = 6e-11
Identities = 80/343 (23%), Positives = 128/343 (37%), Gaps = 39/343 (11%)
Query: 493 LSGISTLLVLPTGAGKSLCYQLPALLYSRRSP---------CLTLVVSPLLSLMDDQVS- 542
LSG + + TG+GK+L Y LPA+++ P CL L + L+ QV+
Sbjct: 206 LSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVAD 265
Query: 543 --GLPPCLKAACIHSGMTRKQRESVLQKIRAAQVHVLMLTPEALVG---AGGLPPAAQLP 597
G LK+ CI+ G + + L++ V + + TP L+ +G L
Sbjct: 266 DYGKCSRLKSTCIYGGAPKGPQIRDLER----GVEICIATPGRLIDFLESG----KTNLR 317
Query: 598 PVAFACIDEAHCLSQWSHNFRPCYLRVCKVLRERMGVHCFLGLTATATRRTASDVAQHLA 657
+ +DEA + F P ++ +R + R+ A D +
Sbjct: 318 RCTYLVLDEADRMLDMG--FEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYT 375
Query: 658 VAEEPDLHGPAPVPTNLHLSVSMDRDTDQALLTLLQGKRFQNLDSIIIYCNRREDTERIA 717
+L A + V M+ + D L+ L++ + + II+ E R
Sbjct: 376 QINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFV---ETKRRCD 432
Query: 718 ALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMG 777
L R W A H ER V F G+ +++AT G
Sbjct: 433 DLTRRMRRDGW-----------PAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRG 481
Query: 778 LDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQP 820
LD DV+ V++ P S E YV +GR R + F P
Sbjct: 482 LDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTP 524
>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
Length = 614
Score = 66.2 bits (160), Expect = 2e-10
Identities = 78/340 (22%), Positives = 128/340 (37%), Gaps = 33/340 (9%)
Query: 493 LSGISTLLVLPTGAGKSLCYQLPALLYSRRSP---------CLTLVVSPLLSLMDDQVSG 543
LSG+ + V TG+GK+L Y LPA+++ P CL L + L+ QV+
Sbjct: 129 LSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAA 188
Query: 544 --LPPC-LKAACIHSGMTRKQRESVLQKIRAAQVHVLMLTPEALVGAGGLPPAAQLPPVA 600
C LK+ CI+ G + + L++ V + + TP L+ L
Sbjct: 189 EYCRACRLKSTCIYGGAPKGPQIRDLER----GVEICIATPGRLIDFLECGKT-NLRRTT 243
Query: 601 FACIDEAHCLSQWSHNFRPCYLRVCKVLRERMGVHCFLGLTATATRRTASDVAQHLAVAE 660
+ +DEA + F P ++ +R + R+ A D +
Sbjct: 244 YLVLDEADRMLDMG--FEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHIN 301
Query: 661 EPDLHGPAPVPTNLHLSVSMDRDTDQALLTLLQGKRFQNLDSIIIYCNRREDTERIAALL 720
L A + V D + D+ L+ L++ + + I++ E R L
Sbjct: 302 IGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFV---ETKRRCDELT 358
Query: 721 RTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDR 780
R W A H +ER V F G+ +++AT GLD
Sbjct: 359 RKMRRDGW-----------PAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDV 407
Query: 781 PDVRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQP 820
DV+ V++ P S E Y+ +GR R + + F P
Sbjct: 408 EDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTP 447
>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
Length = 622
Score = 64.3 bits (155), Expect = 7e-10
Identities = 81/375 (21%), Positives = 148/375 (39%), Gaps = 49/375 (13%)
Query: 466 PAEVFQALEQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPALLY------ 519
PA + + L++ G P Q + + ILSG + + TG+GK+L + LP +++
Sbjct: 189 PAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMFCLEQEK 248
Query: 520 ----SRRSPCLTLVVSPLLSLMDDQVSGL------------PPCLKAACIHSGMTRKQRE 563
S+R L++ P L Q G+ P L+ A GM+ K++
Sbjct: 249 RLPFSKREGPYGLIICPSRELAR-QTHGILEYYCRLLQEDSSPLLRCALCIGGMSVKEQ- 306
Query: 564 SVLQKIRAAQVHVLMLTPEALVGAGGLPPAAQLPPVAFACIDEAHCLSQWSHNFRPCYLR 623
++ IR VH+++ TP L+ L + +DEA +
Sbjct: 307 --METIRHG-VHMMVATPGRLMDLLQ-KKMVSLDICRYLALDEADRMIDMGFEGD----- 357
Query: 624 VCKVLRERMGVHCFLGLTATATRRTASDVAQHLAVAEEPDLHGPAPVPTNLHLSVSMDRD 683
+ + G L +AT ++ + A+ + ++ +L + ++
Sbjct: 358 IRTIFSYFKGQRQTLLFSATMPKKIQNFAKS--ALVKPVTINVGRAGAASLDVIQEVEYV 415
Query: 684 TDQALLTLLQGKRFQNLDSIIIYCNRREDTERIAALLRTCLHAAWVPGSGGRAPKTTAEA 743
++A + L + ++I+ ++ D + I L A A
Sbjct: 416 KEEAKMVYLLECLQKTPPPVLIFAEKKADVDAIHEYLLL--------------KGVEAVA 461
Query: 744 YHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVG 803
H G ER + AF +G+ V+VAT GLD P ++ V++ +P E+YV +G
Sbjct: 462 IHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIG 521
Query: 804 RAGRDGQPAHCHLFL 818
R GR G F+
Sbjct: 522 RTGRSGNTGIATTFI 536
>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
sapiens]
Length = 483
Score = 60.5 bits (145), Expect = 1e-08
Identities = 93/352 (26%), Positives = 136/352 (38%), Gaps = 39/352 (11%)
Query: 475 QLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPALLYSRRSP----CLTLVV 530
QLG + P Q + IL G L TG+GK+ + LP L P CL L
Sbjct: 19 QLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKLSEDPYGIFCLVLTP 78
Query: 531 SPLLSLM---DDQVSGLPPCLKAACIHSGMTRKQRESVLQKIRAAQVHVLMLTPEALVGA 587
+ L+ +V G P LK I GM + L + + HV++ TP L
Sbjct: 79 TRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSR----KPHVVIATPGRLADH 134
Query: 588 GGLPPAAQLPPVAFACIDEA-HCLSQWSHNFRPCYLRVCKVLRERMGVHCFLGLTATATR 646
+ + F +DEA L Q +F + + R F T T T
Sbjct: 135 LRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPARRQTLLF-SATLTDTL 193
Query: 647 RTASDVAQHLAVAEEPDLHGPAPVPTNLHLS----VSMDRDTDQALLTLLQGKRFQNLD- 701
R Q LA + APV T L + ++ D L+ L+Q + ++ D
Sbjct: 194 REL----QGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQRFQDEHEDW 249
Query: 702 SIIIYCNRREDTERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRERRRVQRAFM 761
SIII+ N + + + +LR A H+ M +ER F
Sbjct: 250 SIIIFTNTCKTCQILCMMLRKF--------------SFPTVALHSMMKQKERFAALAKFK 295
Query: 762 QGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVG---RAGRDGQ 810
R+++AT GLD P V+ V++ P + Y+ VG RAGR GQ
Sbjct: 296 SSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQ 347
>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
sapiens]
Length = 407
Score = 58.9 bits (141), Expect = 3e-08
Identities = 79/356 (22%), Positives = 138/356 (38%), Gaps = 40/356 (11%)
Query: 485 QERAVMRILSGISTLLVLPTGAGKSLCYQLPAL--LYSRRSPCLTLVVSPLLSL---MDD 539
Q+RA++ + G + +G GK+ + + L L LV++P L +
Sbjct: 60 QQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQK 119
Query: 540 QVSGLPPCLKAACIHSGMTRKQRESVLQKIRAAQVHVLMLTPEALVGAGGLPPAAQLPP- 598
+ L + A C H+ + + +QK++A H+++ TP + + L P
Sbjct: 120 VILALGDYMGATC-HACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFD---MLNRRYLSPK 175
Query: 599 -VAFACIDEAHCLSQWSHNFRPCYLRVCKVLRERMGVHCFLGLTAT----ATRRTASDVA 653
+ +DEA S F+ + + L + V T T++ D
Sbjct: 176 WIKMFVLDEAD--EMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPI 233
Query: 654 QHLAVAEEPDLHGPAPVPTNLHLSVSMDRDTDQALLTLLQGKRFQNLDSIIIYCNRREDT 713
+ L EE L G ++++R+ + L TL + +I+ N R
Sbjct: 234 RILVKKEELTLEGIK------QFYINVERE-EWKLDTLCDLYETLTITQAVIFLNTRRKV 286
Query: 714 ERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRERRRVQRAFMQGQLRVVVATVA 773
+ + + A T A H M +ER + R F G RV++ T
Sbjct: 287 DWLTEKMH--------------ARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDL 332
Query: 774 FGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELR 829
G+D V V++ LP + E+Y+ +GR GR G+ F+ ED R LR
Sbjct: 333 LARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTE--EDKRILR 386
>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
sapiens]
Length = 796
Score = 57.8 bits (138), Expect = 6e-08
Identities = 86/381 (22%), Positives = 151/381 (39%), Gaps = 48/381 (12%)
Query: 469 VFQALEQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPAL---LYSRRSPC 525
+ +A+ +G + P Q+ + L G TG GK+ + LP L +Y R
Sbjct: 229 LLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLERLIYKPRQAP 288
Query: 526 LT--LVVSPLLSLMDDQVSGLPPCLKAAC------IHSGMTRKQRESVLQKIRAAQVHVL 577
+T LV+ P L QV + L C G+ K +E+ L+ A +L
Sbjct: 289 VTRVLVLVPTREL-GIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEAALR----AAPDIL 343
Query: 578 MLTPEALVGAGGLPPAAQLPPVAFACIDEA-HCLSQWSHNFRPCYLRVCKVLRERMGVHC 636
+ TP L+ P+ L + +DEA L ++ +R+C R+ M
Sbjct: 344 IATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMCSHHRQTM---- 399
Query: 637 FLGLTATATRRTASDVAQ----HLAVAEEPDLHGPAPVPTNLHLSVSMDRDTD-QALLTL 691
T T + + V+ + V D+ AP + + +R+ D +A++
Sbjct: 400 LFSATMTDEVKDLASVSLKNPVRIFVNSNTDV---APFLRQEFIRIRPNREGDREAIVAA 456
Query: 692 LQGKRFQNLDSIIIYCNRREDTERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSR 751
L + F D ++++ ++ R+ LL G E H +
Sbjct: 457 LLTRTFT--DHVMLFTQTKKQAHRMHILL-------------GLMGLQVGEL-HGNLSQT 500
Query: 752 ERRRVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQP 811
+R R F Q+ ++VAT GLD V+ V++ +P + + YV VGR R G+
Sbjct: 501 QRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRA 560
Query: 812 AHCHLFLQPQGEDLRELRRHV 832
+ GED R++ + +
Sbjct: 561 GRS---VSLVGEDERKMLKEI 578
>gi|13129006 nucleolar protein GU2 [Homo sapiens]
Length = 737
Score = 57.8 bits (138), Expect = 6e-08
Identities = 29/84 (34%), Positives = 41/84 (48%)
Query: 738 KTTAEAYHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFES 797
K A+ H + +R + F +G +V+VAT GLD P+V V+ P ES
Sbjct: 412 KQNAQCLHGDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVES 471
Query: 798 YVQAVGRAGRDGQPAHCHLFLQPQ 821
Y+ GR GR G+ C F QP+
Sbjct: 472 YIHRSGRTGRAGRTGICICFYQPR 495
>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
[Homo sapiens]
Length = 411
Score = 57.0 bits (136), Expect = 1e-07
Identities = 33/126 (26%), Positives = 59/126 (46%), Gaps = 16/126 (12%)
Query: 704 IIYCNRREDTERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRERRRVQRAFMQG 763
+I+CN + + + +R T + H M +ER + + F G
Sbjct: 281 VIFCNTKRKVDWLTEKMREA--------------NFTVSSMHGDMPQKERESIMKEFRSG 326
Query: 764 QLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGE 823
RV+++T + GLD P V +++ LP + E Y+ +GR+GR G+ F+ + +
Sbjct: 327 ASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFV--KND 384
Query: 824 DLRELR 829
D+R LR
Sbjct: 385 DIRILR 390
>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
sapiens]
Length = 619
Score = 56.2 bits (134), Expect = 2e-07
Identities = 85/374 (22%), Positives = 147/374 (39%), Gaps = 56/374 (14%)
Query: 473 LEQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPAL---LYSRRSPCLTLV 529
L++ G++ P Q + + L G L TG+GK+ + LP + L+ ++P L+
Sbjct: 218 LKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMRALFESKTPS-ALI 276
Query: 530 VSPLLSLM-------DDQVSGLPPCLKAACIHSGMTRKQRESVLQKIRAAQVHVLMLTPE 582
++P L + +SGLP +K + G+ + LQ+ V V++ TP
Sbjct: 277 LTPTRELAIQIERQAKELMSGLPR-MKTVLLVGGLPLPPQLYRLQQ----HVKVIIATPG 331
Query: 583 ALVGAGGLPPAAQLPPVAFACIDEAHCLSQWSHNFRPCYLRVCKVLRERMGVHCFLGLTA 642
L+ + +L V +DEA + + +V +L E + C L +
Sbjct: 332 RLLDIIK-QSSVELCGVKIVVVDEADTMLKMGFQ-----QQVLDIL-ENIPNDCQTILVS 384
Query: 643 TATRRTASDVAQHLAVAEEPDLHGPAPVPT--------NLHLSVSMDRDT--DQALLTLL 692
+ +A L LH P + T N+ + D + L +L
Sbjct: 385 ATIPTSIEQLASQL-------LHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLFEIL 437
Query: 693 QGKR-FQNLDSIIIYCNRREDTERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSR 751
K+ F+ + + C D A T L + + H+
Sbjct: 438 NDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISI---------------HSEKSQI 482
Query: 752 ERRRVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQP 811
ER+ + + ++G VVV+T G GLD VR V++ +P S + YV +GR GR GQ
Sbjct: 483 ERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQN 542
Query: 812 AHCHLFLQPQGEDL 825
F+ + L
Sbjct: 543 GTAITFINNNSKRL 556
>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
[Homo sapiens]
Length = 406
Score = 55.5 bits (132), Expect = 3e-07
Identities = 75/340 (22%), Positives = 134/340 (39%), Gaps = 44/340 (12%)
Query: 485 QERAVMRILSGISTLLVLPTGAGKSLCYQLPALLYSRRSPCLT--LVVSPLLSL---MDD 539
Q+RA++ + G + +G GK+ + + L T LV++P L +
Sbjct: 59 QQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQK 118
Query: 540 QVSGLPPCLKAACIHSGMTRKQRESVLQKIRAAQVHVLMLTPEALVGAGGLPPAAQLPP- 598
V L + A+C H+ + + +QK++ H+++ TP + + L P
Sbjct: 119 VVMALGDYMGASC-HACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFD---MLNRRYLSPK 174
Query: 599 -VAFACIDEAHCLSQWSHNFRPCYLRVCKVLRERMGVHCFLGLTAT-------ATRRTAS 650
+ +DEA S F+ + + L V + L+AT T++
Sbjct: 175 YIKMFVLDEAD--EMLSRGFKDQIYDIFQKLNSNTQV---VLLSATMPSDVLEVTKKFMR 229
Query: 651 DVAQHLAVAEEPDLHGPAPVPTNLHLSVSMDRDTDQALLTLLQGKRFQNLDSIIIYCNRR 710
D + L EE L G ++++R+ + L TL + +I+ N R
Sbjct: 230 DPIRILVKKEELTLEGIR------QFYINVERE-EWKLDTLCDLYETLTITQAVIFINTR 282
Query: 711 EDTERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRERRRVQRAFMQGQLRVVVA 770
+ + + A T A H M +ER + R F G RV++
Sbjct: 283 RKVDWLTEKMH--------------ARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLIT 328
Query: 771 TVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQ 810
T G+D V V++ LP + E+Y+ +GR GR G+
Sbjct: 329 TDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGR 368
>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
sapiens]
Length = 783
Score = 54.7 bits (130), Expect = 5e-07
Identities = 34/120 (28%), Positives = 52/120 (43%), Gaps = 15/120 (12%)
Query: 704 IIYCNRREDTERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRERRRVQRAFMQG 763
II+C +++ + + S A K A++ H + ++R + F G
Sbjct: 442 IIFCETKKEAQEL---------------SQNSAIKQDAQSLHGDIPQKQREITLKGFRNG 486
Query: 764 QLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGE 823
V+VAT GLD P+V V+ P ESY+ GR GR G+ C F Q + E
Sbjct: 487 SFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFYQHKEE 546
>gi|19924099 synapsin I isoform Ia [Homo sapiens]
Length = 705
Score = 54.3 bits (129), Expect = 7e-07
Identities = 64/251 (25%), Positives = 89/251 (35%), Gaps = 34/251 (13%)
Query: 92 STPGRSRQGSVPDYGQRLKANLKGTLQAGPALGRRPWPLGRASSKASTPKPPGTGPVPSF 151
++PGR G P G AGP +RP P G P PG GP
Sbjct: 426 ASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQG-------GPPQPGPGP---- 474
Query: 152 AEKVSDEPPQLPEPQPRPGRLQHLQ-------ASLSQRLGSLDPGWLQRCHSEVPDFLGA 204
+ P L + P G+ QHL + L QRL S Q P G
Sbjct: 475 ----QRQGPPLQQRPPPQGQ-QHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQ 529
Query: 205 PKACRPDLGSEESQLLIPGESAVLGPGAGSQGPEASAFQEVSIRVGSPQPSSS---GGEK 261
+ RP G + P P Q A ++ S+ +P +S GG++
Sbjct: 530 GRQSRPVAGGPGAP---PAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQ 586
Query: 262 RRWNEEPWESPAQVQQESSQAGPPSEGAGAVAVEEDPPGEPVQAQP-PQPCSSPSNPRYH 320
R+ + PA +++SQAGP + P G +P PQ PS
Sbjct: 587 RQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPS----Q 642
Query: 321 GLSPSSQARAG 331
+ P + A AG
Sbjct: 643 DVPPPATAAAG 653
Score = 35.0 bits (79), Expect = 0.43
Identities = 31/114 (27%), Positives = 44/114 (38%), Gaps = 6/114 (5%)
Query: 230 PGAGSQGPEASAFQEVSIRVGSPQPSSSGGEKRRWNE----EPWESPAQVQQESSQAGPP 285
PG GS G S R S QP+ ++R + +P P Q Q Q PP
Sbjct: 428 PGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGP-QRQGPPLQQRPP 486
Query: 286 SEGAGAVAVEEDPPGEPVQAQPPQPCSSPSNPRYHGLSPS-SQARAGKAEGTAP 338
+G ++ P G P+ + P P S+P P P+ Q R + P
Sbjct: 487 PQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGP 540
>gi|19924097 synapsin I isoform Ib [Homo sapiens]
Length = 669
Score = 54.3 bits (129), Expect = 7e-07
Identities = 64/251 (25%), Positives = 89/251 (35%), Gaps = 34/251 (13%)
Query: 92 STPGRSRQGSVPDYGQRLKANLKGTLQAGPALGRRPWPLGRASSKASTPKPPGTGPVPSF 151
++PGR G P G AGP +RP P G P PG GP
Sbjct: 426 ASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQG-------GPPQPGPGP---- 474
Query: 152 AEKVSDEPPQLPEPQPRPGRLQHLQ-------ASLSQRLGSLDPGWLQRCHSEVPDFLGA 204
+ P L + P G+ QHL + L QRL S Q P G
Sbjct: 475 ----QRQGPPLQQRPPPQGQ-QHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQ 529
Query: 205 PKACRPDLGSEESQLLIPGESAVLGPGAGSQGPEASAFQEVSIRVGSPQPSSS---GGEK 261
+ RP G + P P Q A ++ S+ +P +S GG++
Sbjct: 530 GRQSRPVAGGPGAP---PAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQ 586
Query: 262 RRWNEEPWESPAQVQQESSQAGPPSEGAGAVAVEEDPPGEPVQAQP-PQPCSSPSNPRYH 320
R+ + PA +++SQAGP + P G +P PQ PS
Sbjct: 587 RQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPS----Q 642
Query: 321 GLSPSSQARAG 331
+ P + A AG
Sbjct: 643 DVPPPATAAAG 653
Score = 35.0 bits (79), Expect = 0.43
Identities = 31/114 (27%), Positives = 44/114 (38%), Gaps = 6/114 (5%)
Query: 230 PGAGSQGPEASAFQEVSIRVGSPQPSSSGGEKRRWNE----EPWESPAQVQQESSQAGPP 285
PG GS G S R S QP+ ++R + +P P Q Q Q PP
Sbjct: 428 PGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGP-QRQGPPLQQRPP 486
Query: 286 SEGAGAVAVEEDPPGEPVQAQPPQPCSSPSNPRYHGLSPS-SQARAGKAEGTAP 338
+G ++ P G P+ + P P S+P P P+ Q R + P
Sbjct: 487 PQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGP 540
>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
[Homo sapiens]
Length = 724
Score = 53.1 bits (126), Expect = 2e-06
Identities = 77/370 (20%), Positives = 141/370 (38%), Gaps = 40/370 (10%)
Query: 473 LEQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPALLYSRRSPCLT----- 527
+ + G+ P Q+ ++ IL+G + TG+GK+ + LP L +
Sbjct: 303 IAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKE 362
Query: 528 ------LVVSPLLSLMDD-----QVSGLPPCLKAACIHSGMTRKQRESVLQKIRAAQVHV 576
++V+P L++ + C++A I+ G + S+ Q ++ ++
Sbjct: 363 LQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGT--QLGHSIRQIVQGC--NI 418
Query: 577 LMLTPEALVGAGGLPPAAQLPPVAFACIDEAHCLSQWSHNFRPCYLRVCKVL--RERMGV 634
L TP L+ G L + + +DEA + L C + +E+
Sbjct: 419 LCATPGRLMDIIGKEKIG-LKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQT 477
Query: 635 HCFLGLTATATRRTASDVAQHLAVAEEPDLHGPAPVPTNLHLSVSMDRDTDQALLTLLQG 694
F +R A++ + + G A RD Q +L + Q
Sbjct: 478 LMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGAC------------RDVQQTVLQVGQF 525
Query: 695 KRFQNLDSIIIYCNRREDTERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRERR 754
+ + L I+ R ER + T A ++ + K + + H RER
Sbjct: 526 SKREKLVEIL----RNIGDERTMVFVETKKKADFI-ATFLCQEKISTTSIHGDREQRERE 580
Query: 755 RVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQPAHC 814
+ F G+ V+VAT GLD +V+ V++ LP + + YV +GR GR G
Sbjct: 581 QALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRA 640
Query: 815 HLFLQPQGED 824
F + ++
Sbjct: 641 ISFFDLESDN 650
>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
[Homo sapiens]
Length = 724
Score = 53.1 bits (126), Expect = 2e-06
Identities = 77/370 (20%), Positives = 141/370 (38%), Gaps = 40/370 (10%)
Query: 473 LEQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPALLYSRRSPCLT----- 527
+ + G+ P Q+ ++ IL+G + TG+GK+ + LP L +
Sbjct: 303 IAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKE 362
Query: 528 ------LVVSPLLSLMDD-----QVSGLPPCLKAACIHSGMTRKQRESVLQKIRAAQVHV 576
++V+P L++ + C++A I+ G + S+ Q ++ ++
Sbjct: 363 LQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGT--QLGHSIRQIVQGC--NI 418
Query: 577 LMLTPEALVGAGGLPPAAQLPPVAFACIDEAHCLSQWSHNFRPCYLRVCKVL--RERMGV 634
L TP L+ G L + + +DEA + L C + +E+
Sbjct: 419 LCATPGRLMDIIGKEKIG-LKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQT 477
Query: 635 HCFLGLTATATRRTASDVAQHLAVAEEPDLHGPAPVPTNLHLSVSMDRDTDQALLTLLQG 694
F +R A++ + + G A RD Q +L + Q
Sbjct: 478 LMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGAC------------RDVQQTVLQVGQF 525
Query: 695 KRFQNLDSIIIYCNRREDTERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRERR 754
+ + L I+ R ER + T A ++ + K + + H RER
Sbjct: 526 SKREKLVEIL----RNIGDERTMVFVETKKKADFI-ATFLCQEKISTTSIHGDREQRERE 580
Query: 755 RVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQPAHC 814
+ F G+ V+VAT GLD +V+ V++ LP + + YV +GR GR G
Sbjct: 581 QALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRA 640
Query: 815 HLFLQPQGED 824
F + ++
Sbjct: 641 ISFFDLESDN 650
>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
[Homo sapiens]
Length = 690
Score = 53.1 bits (126), Expect = 2e-06
Identities = 77/370 (20%), Positives = 141/370 (38%), Gaps = 40/370 (10%)
Query: 473 LEQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPALLYSRRSPCLT----- 527
+ + G+ P Q+ ++ IL+G + TG+GK+ + LP L +
Sbjct: 269 IAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKE 328
Query: 528 ------LVVSPLLSLMDD-----QVSGLPPCLKAACIHSGMTRKQRESVLQKIRAAQVHV 576
++V+P L++ + C++A I+ G + S+ Q ++ ++
Sbjct: 329 LQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGT--QLGHSIRQIVQGC--NI 384
Query: 577 LMLTPEALVGAGGLPPAAQLPPVAFACIDEAHCLSQWSHNFRPCYLRVCKVL--RERMGV 634
L TP L+ G L + + +DEA + L C + +E+
Sbjct: 385 LCATPGRLMDIIGKEKIG-LKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQT 443
Query: 635 HCFLGLTATATRRTASDVAQHLAVAEEPDLHGPAPVPTNLHLSVSMDRDTDQALLTLLQG 694
F +R A++ + + G A RD Q +L + Q
Sbjct: 444 LMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGAC------------RDVQQTVLQVGQF 491
Query: 695 KRFQNLDSIIIYCNRREDTERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRERR 754
+ + L I+ R ER + T A ++ + K + + H RER
Sbjct: 492 SKREKLVEIL----RNIGDERTMVFVETKKKADFI-ATFLCQEKISTTSIHGDREQRERE 546
Query: 755 RVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQPAHC 814
+ F G+ V+VAT GLD +V+ V++ LP + + YV +GR GR G
Sbjct: 547 QALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRA 606
Query: 815 HLFLQPQGED 824
F + ++
Sbjct: 607 ISFFDLESDN 616
>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
sapiens]
Length = 483
Score = 52.4 bits (124), Expect = 3e-06
Identities = 84/356 (23%), Positives = 140/356 (39%), Gaps = 46/356 (12%)
Query: 468 EVFQALEQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPAL--LYSRRSPC 525
E+ + ++G + P QE ++ LSG L G GKS Y +P L L ++
Sbjct: 106 ELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNI 165
Query: 526 LTLVVSPLLSLMDDQVSGLPPCLKAACIHSGMTRKQRESVLQKIRAA------QVHVLML 579
+V+ P L QVS + C++ + H G + + +R VHV++
Sbjct: 166 QAMVIVPTRELAL-QVSQI--CIQVSK-HMGGAKVMATTGGTNLRDDIMRLDDTVHVVIA 221
Query: 580 TPEA---LVGAGGLPPAAQLPPVAFACIDEAHCLSQWSHNFRPCYLRVCKVLRERMGVHC 636
TP L+ G A++ V +DEA L S +F + L + +
Sbjct: 222 TPGRILDLIKKG----VAKVDHVQMIVLDEADKLL--SQDFVQIMEDIILTLPKNRQILL 275
Query: 637 FLGLTATATRRTASDVAQ---HLAVAEEPDLHGPAPVPTNLHLSVSMDRDTDQALLTLLQ 693
+ + ++ + Q + + EE L G + + +R L TL
Sbjct: 276 YSATFPLSVQKFMNSHLQKPYEINLMEELTLKG-----VTQYYAYVTERQKVHCLNTLFS 330
Query: 694 GKRFQNLDSIIIYCNRREDTERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRER 753
R Q ++ II+CN + E +A + ++ + HA M R
Sbjct: 331 --RLQ-INQSIIFCNSSQRVELLAKKISQLGYSCFY--------------IHAKMRQEHR 373
Query: 754 RRVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDG 809
RV F G R +V T F G+D V V++ P E+Y+ +GR+GR G
Sbjct: 374 NRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFG 429
>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
[Homo sapiens]
Length = 455
Score = 51.6 bits (122), Expect = 4e-06
Identities = 81/371 (21%), Positives = 140/371 (37%), Gaps = 35/371 (9%)
Query: 471 QALEQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPALLYSRRSP--CLTL 528
+A +QLG Q A+ L G + + TG+GK+ + LP L +P L
Sbjct: 37 EACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLETPQRLFAL 96
Query: 529 VVSPLLSL---MDDQVSGLPPCL--KAACIHSGMTRKQRESVLQKIRAAQVHVLMLTPEA 583
V++P L + +Q L + ++A I G+ + L K + H+++ TP
Sbjct: 97 VLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAK----KPHIIIATPGR 152
Query: 584 LVGAGGLPPAAQLPPVAFACIDEAHCLSQWSHNFRPCYLRVCKVL-RERMGVHCFLGLTA 642
L+ L + + +DEA + +F ++ KV+ R+R +T
Sbjct: 153 LIDHLENTKGFNLRALKYLVMDEADRILNM--DFETEVDKILKVIPRDRKTFLFSATMTK 210
Query: 643 TATRRTASDVAQHLAVAEEPDLHGPAPVPTNLHLSVSMDRDTDQA-LLTLLQGKRFQNLD 701
+ + + + A + S +DT +L L G F
Sbjct: 211 KVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFKDTYLVYILNELAGNSF---- 266
Query: 702 SIIIYCNRREDTERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRERRRVQRAFM 761
+I+C+ +T+R A LLR TA H M +R F
Sbjct: 267 --MIFCSTCNNTQRTALLLRNL--------------GFTAIPLHGQMSQSKRLGSLNKFK 310
Query: 762 QGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQ 821
+++AT GLD P V V++ +P + Y+ VGR R G+ F+
Sbjct: 311 AKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQY 370
Query: 822 GEDLRELRRHV 832
+L + H+
Sbjct: 371 DVELFQRIEHL 381
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,945,167
Number of Sequences: 37866
Number of extensions: 3363660
Number of successful extensions: 20585
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 103
Number of HSP's successfully gapped in prelim test: 670
Number of HSP's that attempted gapping in prelim test: 17401
Number of HSP's gapped (non-prelim): 3730
length of query: 1208
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1094
effective length of database: 13,930,794
effective search space: 15240288636
effective search space used: 15240288636
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.