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Search of human proteins with 116805332
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116805332 musculin [Homo sapiens]
(206 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116805332 musculin [Homo sapiens] 417 e-117
gi|38202237 transcription factor 21 [Homo sapiens] 193 1e-49
gi|38202239 transcription factor 21 [Homo sapiens] 193 1e-49
gi|4507741 twist [Homo sapiens] 82 4e-16
gi|239749439 PREDICTED: similar to transcription factor 23 [Homo... 79 4e-15
gi|239743573 PREDICTED: similar to transcription factor 23 [Homo... 79 4e-15
gi|148922889 scleraxis homolog B [Homo sapiens] 78 6e-15
gi|186972126 scleraxis homolog A [Homo sapiens] 78 6e-15
gi|48255909 basic helix-loop-helix transcription factor 15 [Homo... 78 6e-15
gi|239754900 PREDICTED: similar to transcription factor 23 [Homo... 77 1e-14
gi|17981708 twist homolog 2 [Homo sapiens] 71 6e-13
gi|12545384 basic helix-loop-helix transcription factor HAND2 [H... 68 5e-12
gi|75677394 transcription factor 23 [Homo sapiens] 66 2e-11
gi|31077092 neurogenin 2 [Homo sapiens] 65 5e-11
gi|161484632 nescient helix loop helix 2 [Homo sapiens] 63 2e-10
gi|5031945 nescient helix loop helix 2 [Homo sapiens] 63 2e-10
gi|30039710 pancreas specific transcription factor, 1a [Homo sap... 62 3e-10
gi|22748877 basic helix-loop-helix domain containing, class B, 5... 62 4e-10
gi|21553337 atonal homolog 7 [Homo sapiens] 62 4e-10
gi|68989258 neurogenin 3 [Homo sapiens] 60 2e-09
gi|5031943 nescient helix loop helix 1 [Homo sapiens] 60 2e-09
gi|98986461 neurogenic differentiation 2 [Homo sapiens] 59 2e-09
gi|4885075 atonal homolog 1 [Homo sapiens] 58 6e-09
gi|4758506 basic helix-loop-helix transcription factor HAND1 [Ho... 57 1e-08
gi|38455396 neurogenin 1 [Homo sapiens] 57 1e-08
gi|23097242 nephew of atonal 3 [Homo sapiens] 57 1e-08
gi|29126247 basic helix-loop-helix family, member a15 [Homo sapi... 56 2e-08
gi|27475985 neurogenic differentiation 6 [Homo sapiens] 55 3e-08
gi|206597481 achaete-scute complex-like 4 [Homo sapiens] 54 9e-08
gi|226498192 atonal homolog 8 [Homo sapiens] 53 2e-07
>gi|116805332 musculin [Homo sapiens]
Length = 206
Score = 417 bits (1071), Expect = e-117
Identities = 206/206 (100%), Positives = 206/206 (100%)
Query: 1 MSTGSVSDPEEMELRGLQREYPVPASKRPPLRGVERSYASPSDNSSAEEEDPDGEEERCA 60
MSTGSVSDPEEMELRGLQREYPVPASKRPPLRGVERSYASPSDNSSAEEEDPDGEEERCA
Sbjct: 1 MSTGSVSDPEEMELRGLQREYPVPASKRPPLRGVERSYASPSDNSSAEEEDPDGEEERCA 60
Query: 61 LGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERARM 120
LGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERARM
Sbjct: 61 LGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERARM 120
Query: 121 RVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYENGYVHPVNLTW 180
RVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYENGYVHPVNLTW
Sbjct: 121 RVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYENGYVHPVNLTW 180
Query: 181 PFVVSGRPDSDTKEVSAANRLCGTTA 206
PFVVSGRPDSDTKEVSAANRLCGTTA
Sbjct: 181 PFVVSGRPDSDTKEVSAANRLCGTTA 206
>gi|38202237 transcription factor 21 [Homo sapiens]
Length = 179
Score = 193 bits (490), Expect = 1e-49
Identities = 112/206 (54%), Positives = 135/206 (65%), Gaps = 28/206 (13%)
Query: 1 MSTGSVSDPEEMELRGLQREYPVPASKRPPLRGVERSYASPSDNSSAEEEDPDGEEERCA 60
MSTGS+SD E+++ V + L+ ++ + + N S EE
Sbjct: 1 MSTGSLSDVEDLQ--------EVEMLECDGLK-MDSNKEFVTSNESTEE----------- 40
Query: 61 LGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERARM 120
+ C+ P+ G GG G KK P G + E KQ QRNAANARERARM
Sbjct: 41 ------SSNCENGSPQ-KGRGGLGKRRKAPTKKS-PLSGVSQEGKQVQRNAANARERARM 92
Query: 121 RVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYENGYVHPVNLTW 180
RVLSKAFSRLKT+LPWVPPDTKLSKLDTLRLASSYIAHLRQ+L D+YENGY+HPVNLTW
Sbjct: 93 RVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHLRQILANDKYENGYIHPVNLTW 152
Query: 181 PFVVSGRPDSDTKEVSAANRLCGTTA 206
PF+V+G+P+SD KEV A+RLCGTTA
Sbjct: 153 PFMVAGKPESDLKEVVTASRLCGTTA 178
>gi|38202239 transcription factor 21 [Homo sapiens]
Length = 179
Score = 193 bits (490), Expect = 1e-49
Identities = 112/206 (54%), Positives = 135/206 (65%), Gaps = 28/206 (13%)
Query: 1 MSTGSVSDPEEMELRGLQREYPVPASKRPPLRGVERSYASPSDNSSAEEEDPDGEEERCA 60
MSTGS+SD E+++ V + L+ ++ + + N S EE
Sbjct: 1 MSTGSLSDVEDLQ--------EVEMLECDGLK-MDSNKEFVTSNESTEE----------- 40
Query: 61 LGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERARM 120
+ C+ P+ G GG G KK P G + E KQ QRNAANARERARM
Sbjct: 41 ------SSNCENGSPQ-KGRGGLGKRRKAPTKKS-PLSGVSQEGKQVQRNAANARERARM 92
Query: 121 RVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYENGYVHPVNLTW 180
RVLSKAFSRLKT+LPWVPPDTKLSKLDTLRLASSYIAHLRQ+L D+YENGY+HPVNLTW
Sbjct: 93 RVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHLRQILANDKYENGYIHPVNLTW 152
Query: 181 PFVVSGRPDSDTKEVSAANRLCGTTA 206
PF+V+G+P+SD KEV A+RLCGTTA
Sbjct: 153 PFMVAGKPESDLKEVVTASRLCGTTA 178
>gi|4507741 twist [Homo sapiens]
Length = 202
Score = 81.6 bits (200), Expect = 4e-16
Identities = 65/189 (34%), Positives = 93/189 (49%), Gaps = 36/189 (19%)
Query: 31 LRGVERSYASPSDNS-SAEEEDPD----------GEEERCALGTAGSAEG---------- 69
++ V S SP+D+S S EE+PD G + R + +AG G
Sbjct: 2 MQDVSSSPVSPADDSLSNSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGVG 61
Query: 70 --------CKRKR-PRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERARM 120
+ KR + AG GG GG+ GGGG + E Q+QR AN RER R
Sbjct: 62 GGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMANVRERQRT 121
Query: 121 RVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYEN-----GYVHP 175
+ L++AF+ L+ +P +P D KLSK+ TL+LA+ YI L Q+LQ D ++ YV
Sbjct: 122 QSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSDELDSKMASCSYVAH 180
Query: 176 VNLTWPFVV 184
L++ F V
Sbjct: 181 ERLSYAFSV 189
>gi|239749439 PREDICTED: similar to transcription factor 23 [Homo
sapiens]
Length = 167
Score = 78.6 bits (192), Expect = 4e-15
Identities = 54/141 (38%), Positives = 68/141 (48%), Gaps = 24/141 (17%)
Query: 52 PDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNA 111
P G + A A + RP G G AG G PA +AA
Sbjct: 6 PAGSPLSASAEPAPLAAAIRDSRPGRTGPGPAGPGGGSRSGSGRPAAANAA--------- 56
Query: 112 ANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYE-- 169
RER+R++ L AF L+ +LP VPPDTKLSKLD L LA++YIAHL + LQ+D
Sbjct: 57 ---RERSRVQTLRHAFLELQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDDAEAPA 113
Query: 170 ---------NGYVHPVNLTWP 181
+GY+HPV WP
Sbjct: 114 DAGLGALRGDGYLHPVK-KWP 133
>gi|239743573 PREDICTED: similar to transcription factor 23 [Homo
sapiens]
Length = 167
Score = 78.6 bits (192), Expect = 4e-15
Identities = 54/141 (38%), Positives = 68/141 (48%), Gaps = 24/141 (17%)
Query: 52 PDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNA 111
P G + A A + RP G G AG G PA +AA
Sbjct: 6 PAGSPLSASAEPAPLAAAIRDSRPGRTGPGPAGPGGGSRSGSGRPAAANAA--------- 56
Query: 112 ANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYE-- 169
RER+R++ L AF L+ +LP VPPDTKLSKLD L LA++YIAHL + LQ+D
Sbjct: 57 ---RERSRVQTLRHAFLELQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDDAEAPA 113
Query: 170 ---------NGYVHPVNLTWP 181
+GY+HPV WP
Sbjct: 114 DAGLGALRGDGYLHPVK-KWP 133
>gi|148922889 scleraxis homolog B [Homo sapiens]
Length = 201
Score = 77.8 bits (190), Expect = 6e-15
Identities = 51/122 (41%), Positives = 68/122 (55%), Gaps = 20/122 (16%)
Query: 42 SDNSSAEEEDPDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSA 101
SD+S ++E+ RC L A G +R AGGGG GG G ++P
Sbjct: 30 SDSSGSDEKPCRVHAARCGLQGARRRAGGRR-----AGGGGPGGRPG---REP------- 74
Query: 102 AECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQ 161
QR+ ANARER R ++ AF+ L+T +P P D KLSK++TLRLASSYI+HL
Sbjct: 75 -----RQRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGN 129
Query: 162 LL 163
+L
Sbjct: 130 VL 131
>gi|186972126 scleraxis homolog A [Homo sapiens]
Length = 201
Score = 77.8 bits (190), Expect = 6e-15
Identities = 51/122 (41%), Positives = 68/122 (55%), Gaps = 20/122 (16%)
Query: 42 SDNSSAEEEDPDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSA 101
SD+S ++E+ RC L A G +R AGGGG GG G ++P
Sbjct: 30 SDSSGSDEKPCRVHAARCGLQGARRRAGGRR-----AGGGGPGGRPG---REP------- 74
Query: 102 AECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQ 161
QR+ ANARER R ++ AF+ L+T +P P D KLSK++TLRLASSYI+HL
Sbjct: 75 -----RQRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGN 129
Query: 162 LL 163
+L
Sbjct: 130 VL 131
>gi|48255909 basic helix-loop-helix transcription factor 15 [Homo
sapiens]
Length = 199
Score = 77.8 bits (190), Expect = 6e-15
Identities = 49/113 (43%), Positives = 62/113 (54%), Gaps = 9/113 (7%)
Query: 53 DGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGS--AGGGGKKPLPAKGSAAECKQSQRN 110
+ EE R + + GC G G GG AGGGG G+ QR
Sbjct: 23 EDEENRSESDASDQSFGCCEGPEAARRGPGPGGGRRAGGGG-------GAGPVVVVRQRQ 75
Query: 111 AANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLL 163
AANARER R + ++ AF+ L+T +P P D KLSK++TLRLASSYIAHL +L
Sbjct: 76 AANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYIAHLANVL 128
>gi|239754900 PREDICTED: similar to transcription factor 23 [Homo
sapiens]
Length = 167
Score = 77.0 bits (188), Expect = 1e-14
Identities = 57/143 (39%), Positives = 71/143 (49%), Gaps = 28/143 (19%)
Query: 52 PDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNA 111
P G + A A + RP G G AG GGG C S R A
Sbjct: 6 PAGSPLSASAEPAPLAAAIRDXRPGRTGPGPAG--LGGGS------------CSGSGRPA 51
Query: 112 AN--ARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYE 169
A ARER+R++ L AF ++ +LP VPPDTKLSKLD L LA++YIAHL + LQ+D
Sbjct: 52 AENAARERSRVQTLRHAFLEVQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDDAEA 111
Query: 170 -----------NGYVHPVNLTWP 181
+GY+HPV WP
Sbjct: 112 PADAGLGALRGDGYLHPVK-KWP 133
>gi|17981708 twist homolog 2 [Homo sapiens]
Length = 160
Score = 71.2 bits (173), Expect = 6e-13
Identities = 56/153 (36%), Positives = 81/153 (52%), Gaps = 17/153 (11%)
Query: 37 SYASPSDNSSAEEEDPDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLP 96
S SP D+ EE+ + + +R G KR+ + + G+ + G GKK P
Sbjct: 7 SPVSPVDSLGTSEEELERQPKRF---------GRKRRYSKKSSEDGSP-TPGKRGKKGSP 56
Query: 97 AKGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYI 156
+ S E QSQR AN RER R + L++AF+ L+ +P +P D KLSK+ TL+LA+ YI
Sbjct: 57 SAQSFEEL-QSQRILANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYI 114
Query: 157 AHLRQLLQEDRYEN-----GYVHPVNLTWPFVV 184
L Q+LQ D +N YV L++ F V
Sbjct: 115 DFLYQVLQSDEMDNKMTSCSYVAHERLSYAFSV 147
>gi|12545384 basic helix-loop-helix transcription factor HAND2 [Homo
sapiens]
Length = 217
Score = 68.2 bits (165), Expect = 5e-12
Identities = 50/127 (39%), Positives = 63/127 (49%), Gaps = 22/127 (17%)
Query: 40 SPSDNSSAEEEDPDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKG 99
SP D S A P+ A G AG P AG G GG P P K
Sbjct: 54 SPPDYSMALSYSPE-----YASGAAGLDHSHYGGVPPGAGPPGLGG--------PRPVK- 99
Query: 100 SAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHL 159
+R AN +ER R + ++ AF+ L+ +P VP DTKLSK+ TLRLA+SYIA+L
Sbjct: 100 --------RRGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYL 151
Query: 160 RQLLQED 166
LL +D
Sbjct: 152 MDLLAKD 158
>gi|75677394 transcription factor 23 [Homo sapiens]
Length = 214
Score = 65.9 bits (159), Expect = 2e-11
Identities = 39/77 (50%), Positives = 50/77 (64%), Gaps = 10/77 (12%)
Query: 114 ARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQED------- 166
ARER+R+R L +AF L+ +LP VPPDTKLSKLD L LA+SYIAHL + L +
Sbjct: 83 ARERSRVRTLRQAFLALQAALPAVPPDTKLSKLDVLVLAASYIAHLTRTLGHELPGPAWP 142
Query: 167 RYENG--YVHPVNLTWP 181
+ G Y+HP+ WP
Sbjct: 143 PFLRGLRYLHPLK-KWP 158
>gi|31077092 neurogenin 2 [Homo sapiens]
Length = 272
Score = 64.7 bits (156), Expect = 5e-11
Identities = 50/145 (34%), Positives = 71/145 (48%), Gaps = 33/145 (22%)
Query: 44 NSSAEEEDPDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGG-SAGGGGKKPLPAKGSAA 102
+SSA+EE+ EEE G++ G +R+R AG G GG +AG G +P G
Sbjct: 34 SSSADEEE---EEE------PGASGGARRQRGAEAGQGARGGVAAGAEGCRPARLLGLVH 84
Query: 103 ECKQ-----------------------SQRNAANARERARMRVLSKAFSRLKTSLPWVPP 139
+CK+ ++R AN RER RM L+ A L+ LP P
Sbjct: 85 DCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPE 144
Query: 140 DTKLSKLDTLRLASSYIAHLRQLLQ 164
D KL+K++TLR A +YI L + L+
Sbjct: 145 DAKLTKIETLRFAHNYIWALTETLR 169
>gi|161484632 nescient helix loop helix 2 [Homo sapiens]
Length = 135
Score = 63.2 bits (152), Expect = 2e-10
Identities = 46/133 (34%), Positives = 67/133 (50%), Gaps = 15/133 (11%)
Query: 39 ASPSDNSSAEEEDPD--GEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLP 96
A+ SD+ S+ DP+ G + LG+ E + A G G GGS P P
Sbjct: 8 AADSDHPSSAHSDPESLGGTDTKVLGSVSDLEPVEE-----AEGDGKGGSRAA--LYPHP 60
Query: 97 AKGSAAECKQSQRNAAN------ARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLR 150
+ S E ++ +R A RER R+ + AF+ L+ LP +PPD KLSK++ LR
Sbjct: 61 QQLSREEKRRRRRATAKYRSAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILR 120
Query: 151 LASSYIAHLRQLL 163
LA YI++L +L
Sbjct: 121 LAICYISYLNHVL 133
>gi|5031945 nescient helix loop helix 2 [Homo sapiens]
Length = 135
Score = 63.2 bits (152), Expect = 2e-10
Identities = 46/133 (34%), Positives = 67/133 (50%), Gaps = 15/133 (11%)
Query: 39 ASPSDNSSAEEEDPD--GEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLP 96
A+ SD+ S+ DP+ G + LG+ E + A G G GGS P P
Sbjct: 8 AADSDHPSSAHSDPESLGGTDTKVLGSVSDLEPVEE-----AEGDGKGGSRAA--LYPHP 60
Query: 97 AKGSAAECKQSQRNAAN------ARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLR 150
+ S E ++ +R A RER R+ + AF+ L+ LP +PPD KLSK++ LR
Sbjct: 61 QQLSREEKRRRRRATAKYRSAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILR 120
Query: 151 LASSYIAHLRQLL 163
LA YI++L +L
Sbjct: 121 LAICYISYLNHVL 133
>gi|30039710 pancreas specific transcription factor, 1a [Homo
sapiens]
Length = 328
Score = 62.0 bits (149), Expect = 3e-10
Identities = 51/158 (32%), Positives = 70/158 (44%), Gaps = 22/158 (13%)
Query: 24 PASKRPPLRGVERSYASPSDNSSAEEEDPDGEEERCALG--------TAGSAEGCKR--- 72
PA PL + A PS E +D G C G + GS C
Sbjct: 72 PAPPAAPL-----ALAPPSSGGLGEPDDGGGGGYCCETGAPPGGFPYSPGSPPSCLAYPC 126
Query: 73 KRPRVAGGG----GAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERARMRVLSKAFS 128
V G G G+A ++ + A Q R AAN RER RM+ ++ AF
Sbjct: 127 AGAAVLSPGARLRGLSGAAAAAARRRRRVRSEAE--LQQLRQAANVRERRRMQSINDAFE 184
Query: 129 RLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQED 166
L++ +P +P + +LSK+DTLRLA YI L +L+Q D
Sbjct: 185 GLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQAD 222
>gi|22748877 basic helix-loop-helix domain containing, class B, 5
[Homo sapiens]
Length = 381
Score = 61.6 bits (148), Expect = 4e-10
Identities = 51/182 (28%), Positives = 73/182 (40%), Gaps = 40/182 (21%)
Query: 33 GVERSYASPSDNSSAEEEDPDGEEERCAL-----------------GTAGSAEGCKRKRP 75
G S S +++S E+ D + RC L G A +AEGC
Sbjct: 130 GESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSNAHL 189
Query: 76 R---------------------VAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANA 114
+GGGG GS GG + ++ +++ R NA
Sbjct: 190 HGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKSKEQKALRLNINA 249
Query: 115 RERARMRVLSKAFSRLKTSLPWV--PPDTKLSKLDTLRLASSYIAHLRQLLQEDRYENGY 172
RER RM L+ A L+ +P+ P KLSK+ TL LA +YI Q L+E R Y
Sbjct: 250 RERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALEEMRRLVAY 309
Query: 173 VH 174
++
Sbjct: 310 LN 311
Score = 28.1 bits (61), Expect = 5.5
Identities = 11/17 (64%), Positives = 12/17 (70%)
Query: 75 PRVAGGGGAGGSAGGGG 91
P GGGG+ GS GGGG
Sbjct: 79 PPGGGGGGSAGSGGGGG 95
>gi|21553337 atonal homolog 7 [Homo sapiens]
Length = 152
Score = 61.6 bits (148), Expect = 4e-10
Identities = 39/94 (41%), Positives = 52/94 (55%), Gaps = 9/94 (9%)
Query: 72 RKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERARMRVLSKAFSRLK 131
R P AGG G+ G G+ A+ +R AANARER RM+ L+ AF RL+
Sbjct: 14 RVAPPCAGGTECAGTCAGAGRLESAAR---------RRLAANARERRRMQGLNTAFDRLR 64
Query: 132 TSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQE 165
+P D KLSK +TL++A SYI L ++L E
Sbjct: 65 RVVPQWGQDKKLSKYETLQMALSYIMALTRILAE 98
>gi|68989258 neurogenin 3 [Homo sapiens]
Length = 214
Score = 59.7 bits (143), Expect = 2e-09
Identities = 43/137 (31%), Positives = 64/137 (46%), Gaps = 15/137 (10%)
Query: 32 RGVERSYASPSDNS----SAEEEDPDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSA 87
R ERS+ S++ ++ P CA G G RK A
Sbjct: 15 RETERSFPRASEDEVTCPTSAPPSPTRTRGNCAEAEEGGCRGAPRKL-----------RA 63
Query: 88 GGGGKKPLPAKGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLD 147
GG+ ++ + ++ ++S+R AN RER RM L+ A L+ LP P D KL+K++
Sbjct: 64 RRGGRSRPKSELALSKQRRSRRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLTKIE 123
Query: 148 TLRLASSYIAHLRQLLQ 164
TLR A +YI L Q L+
Sbjct: 124 TLRFAHNYIWALTQTLR 140
>gi|5031943 nescient helix loop helix 1 [Homo sapiens]
Length = 133
Score = 59.7 bits (143), Expect = 2e-09
Identities = 43/133 (32%), Positives = 57/133 (42%), Gaps = 18/133 (13%)
Query: 44 NSSAEEED--PDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSA 101
NS E D P E G G P AG GG GG G + P +
Sbjct: 4 NSDTMELDLPPTHSETESGFSDCGGGAG-----PDGAGPGGPGGGQARGPEPGEPGRKDL 58
Query: 102 AECKQSQRN-----------AANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLR 150
+ +R A RER R+ + AF+ L+ LP +PPD KLSK++ LR
Sbjct: 59 QHLSREERRRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILR 118
Query: 151 LASSYIAHLRQLL 163
LA YI++L +L
Sbjct: 119 LAICYISYLNHVL 131
>gi|98986461 neurogenic differentiation 2 [Homo sapiens]
Length = 382
Score = 59.3 bits (142), Expect = 2e-09
Identities = 49/148 (33%), Positives = 71/148 (47%), Gaps = 19/148 (12%)
Query: 22 PVPASKRPPLRGVERSYASPSDNSSAEEEDPDGEEERCALGTAGSAEGCKRKRPRVAGGG 81
P A+K PLRG E + A+ ++ E + EEE AEG +RP+ G
Sbjct: 51 PARAAKPVPLRGEEGTEATLAEVKEEGELGGEEEEEEEEEEGLDEAEG---ERPKKRG-- 105
Query: 82 GAGGSAGGGGKKPLPAKGSAAECKQSQ--RNAANARERARMRVLSKAFSRLKTSLPWVPP 139
P K + A ++S+ R ANARER RM L+ A L+ +P
Sbjct: 106 ------------PKKRKMTKARLERSKLRRQKANARERNRMHDLNAALDNLRKVVPCYSK 153
Query: 140 DTKLSKLDTLRLASSYIAHLRQLLQEDR 167
KLSK++TLRLA +YI L ++L+ +
Sbjct: 154 TQKLSKIETLRLAKNYIWALSEILRSGK 181
>gi|4885075 atonal homolog 1 [Homo sapiens]
Length = 354
Score = 57.8 bits (138), Expect = 6e-09
Identities = 44/127 (34%), Positives = 62/127 (48%), Gaps = 17/127 (13%)
Query: 48 EEEDPDGEEERCALGTAGSAEG----------CKRKRPRVAGGGGAGGSAGGGGKKPLPA 97
+E D GE R + G A S++ CK K GG G ++ P+
Sbjct: 97 DEVDGRGELVRRSSGGASSSKSPGPVKVREQLCKLK-------GGVVVDELGCSRQRAPS 149
Query: 98 KGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIA 157
++ +R AANARER RM L+ AF +L+ +P D KLSK +TL++A YI
Sbjct: 150 SKQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYIN 209
Query: 158 HLRQLLQ 164
L +LLQ
Sbjct: 210 ALSELLQ 216
>gi|4758506 basic helix-loop-helix transcription factor HAND1 [Homo
sapiens]
Length = 215
Score = 57.0 bits (136), Expect = 1e-08
Identities = 36/94 (38%), Positives = 51/94 (54%), Gaps = 5/94 (5%)
Query: 75 PRVAGGGGAGGSAGGGGKKP--LPAKGSAAECKQSQRNAANARERARMRVLSKAFSRLKT 132
P A A G G+ P L A G ++ + +ER R ++ AF+ L+
Sbjct: 63 PAAAAAATAYGPDARPGQSPGRLEALGGRLG---RRKGSGPKKERRRTESINSAFAELRE 119
Query: 133 SLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQED 166
+P VP DTKLSK+ TLRLA+SYIA+L +L +D
Sbjct: 120 CIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKD 153
>gi|38455396 neurogenin 1 [Homo sapiens]
Length = 237
Score = 56.6 bits (135), Expect = 1e-08
Identities = 46/140 (32%), Positives = 69/140 (49%), Gaps = 15/140 (10%)
Query: 40 SPSDNSSAEEEDPDG---EEERCA-LGTAGSAEG----CKRKRPRVAGGGGAGGSAGGG- 90
S D +S+ D G +EE CA L A SA G +R P ++ G+
Sbjct: 10 SDLDCASSSGSDLSGFLTDEEDCARLQQAASASGPPAPARRGAPNISRASEVPGAQDDEQ 69
Query: 91 ------GKKPLPAKGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLS 144
G+ + ++ ++S+R AN RER RM L+ A L++ LP P DTKL+
Sbjct: 70 ERRRRRGRTRVRSEALLHSLRRSRRVKANDRERNRMHNLNAALDALRSVLPSFPDDTKLT 129
Query: 145 KLDTLRLASSYIAHLRQLLQ 164
K++TLR A +YI L + L+
Sbjct: 130 KIETLRFAYNYIWALAETLR 149
>gi|23097242 nephew of atonal 3 [Homo sapiens]
Length = 166
Score = 56.6 bits (135), Expect = 1e-08
Identities = 42/126 (33%), Positives = 65/126 (51%), Gaps = 15/126 (11%)
Query: 47 AEEEDPDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQ 106
A E+ D EEE C + E + +R G G S G K+
Sbjct: 55 ARFEEGDPEEEECEVDQGDGEEEEEEER-------GRGVSLLGRPKRK-------RVITY 100
Query: 107 SQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQE- 165
+QR AAN RER RM L++AF +L+ +P + +LS+++TLRLA YI+ + +LL+
Sbjct: 101 AQRQAANIRERKRMFNLNEAFDQLRRKVPTFAYEKRLSRIETLRLAIVYISFMTELLESC 160
Query: 166 DRYENG 171
++ E+G
Sbjct: 161 EKKESG 166
>gi|29126247 basic helix-loop-helix family, member a15 [Homo
sapiens]
Length = 189
Score = 56.2 bits (134), Expect = 2e-08
Identities = 42/139 (30%), Positives = 64/139 (46%), Gaps = 21/139 (15%)
Query: 24 PASKRPPLRGVERSYASPSDNSSAEEEDPD---GEEERCALGTAGSAEGCKRKRPRVAGG 80
P +R P++ E + + + S P+ G R A A + +R+RP
Sbjct: 7 PPRRRAPVQDTEATPGEGTPDGSLPNPGPEPAKGLRSRPARAAARAPGEGRRRRP----- 61
Query: 81 GGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPD 140
G +G GG++ + +R +N RER RM L+ AF L+ +P V D
Sbjct: 62 ----GPSGPGGRR---------DSSIQRRLESNERERQRMHKLNNAFQALREVIPHVRAD 108
Query: 141 TKLSKLDTLRLASSYIAHL 159
KLSK++TL LA +YI L
Sbjct: 109 KKLSKIETLTLAKNYIKSL 127
>gi|27475985 neurogenic differentiation 6 [Homo sapiens]
Length = 337
Score = 55.5 bits (132), Expect = 3e-08
Identities = 53/168 (31%), Positives = 70/168 (41%), Gaps = 33/168 (19%)
Query: 5 SVSDPEEMELRGLQREY--------PVPASKRPPLRGVERSYASPSDNSSAEEEDPDGEE 56
SV PE R RE P SK+ LRG A P + + EEE+ D EE
Sbjct: 9 SVVMPESQMCRKFSRECEDQKQIKKPESFSKQIVLRGKSIKRA-PGEETEKEEEEEDREE 67
Query: 57 ERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARE 116
E G R+R G + E + +R ANARE
Sbjct: 68 E--------DENGLPRRR----------------GLRKKKTTKLRLERVKFRRQEANARE 103
Query: 117 RARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQ 164
R RM L+ A L+ +P KLSK++TLRLA +YI L ++L+
Sbjct: 104 RNRMHGLNDALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILR 151
>gi|206597481 achaete-scute complex-like 4 [Homo sapiens]
Length = 173
Score = 53.9 bits (128), Expect = 9e-08
Identities = 40/116 (34%), Positives = 59/116 (50%), Gaps = 11/116 (9%)
Query: 61 LGTAGSAEGCKRKRP-RVAGGGGAG-------GSAGGGGKKPLPAKGSAAECKQSQRNAA 112
LG G+ G R+ P RVA A G A G P+P + +RN
Sbjct: 22 LGVPGTLPGLPRRDPLRVALRLDAACWEWARSGCARGWQYLPVPLDSAFEPAFLRKRNE- 80
Query: 113 NARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRY 168
RER R+R +++ ++RL+ LP D +LSK++TLR A YI HL++LL+ +
Sbjct: 81 --RERQRVRCVNEGYARLRDHLPRELADKRLSKVETLRAAIDYIKHLQELLERQAW 134
>gi|226498192 atonal homolog 8 [Homo sapiens]
Length = 321
Score = 52.8 bits (125), Expect = 2e-07
Identities = 33/84 (39%), Positives = 47/84 (55%), Gaps = 3/84 (3%)
Query: 86 SAGGGGKKPLPAKGSAAECK---QSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTK 142
S+ K+P A +++E K Q++R ANARER R+ +S AF L+ +P K
Sbjct: 206 SSASPRKRPGEATAASSEIKALQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYGQK 265
Query: 143 LSKLDTLRLASSYIAHLRQLLQED 166
LSKL LR+A +YI L +L D
Sbjct: 266 LSKLAILRIACNYILSLARLADLD 289
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.128 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,143,117
Number of Sequences: 37866
Number of extensions: 476824
Number of successful extensions: 7454
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 322
Number of HSP's successfully gapped in prelim test: 268
Number of HSP's that attempted gapping in prelim test: 4458
Number of HSP's gapped (non-prelim): 2133
length of query: 206
length of database: 18,247,518
effective HSP length: 97
effective length of query: 109
effective length of database: 14,574,516
effective search space: 1588622244
effective search space used: 1588622244
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.