Guide to the Human Genome
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Search of human proteins with 116734702

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116734702 homeobox D13 [Homo sapiens]
         (343 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116734702 homeobox D13 [Homo sapiens]                              693   0.0  
gi|24497554 homeobox A13 [Homo sapiens]                               272   4e-73
gi|24497536 homeobox C13 [Homo sapiens]                               264   8e-71
gi|62865866 homeobox B13 [Homo sapiens]                               218   5e-57
gi|23510368 homeobox D11 [Homo sapiens]                                96   5e-20
gi|194353946 homeobox D12 [Homo sapiens]                               84   2e-16
gi|5031759 homeobox A11 [Homo sapiens]                                 80   3e-15
gi|7657166 homeobox C11 [Homo sapiens]                                 80   3e-15
gi|27804315 homeobox C12 [Homo sapiens]                                79   5e-15
gi|194363768 homeobox D9 [Homo sapiens]                                78   1e-14
gi|15029508 homeobox B9 [Homo sapiens]                                 75   9e-14
gi|182765442 homeobox A10 isoform a [Homo sapiens]                     74   1e-13
gi|23510366 homeobox D10 [Homo sapiens]                                73   3e-13
gi|24497547 homeobox C9 [Homo sapiens]                                 73   3e-13
gi|23097236 homeobox A9 [Homo sapiens]                                 73   4e-13
gi|24497533 homeobox C10 [Homo sapiens]                                72   6e-13
gi|24497551 homeobox A10 isoform b [Homo sapiens]                      72   9e-13
gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]           69   5e-12
gi|89257348 homeo box HB9 [Homo sapiens]                               67   2e-11
gi|13273317 homeobox B8 [Homo sapiens]                                 64   3e-10
gi|12056969 homeobox C8 [Homo sapiens]                                 63   3e-10
gi|18959212 GS homeobox 2 [Homo sapiens]                               63   3e-10
gi|91208415 mesenchyme homeobox 1 isoform 3 [Homo sapiens]             62   6e-10
gi|4758710 mesenchyme homeobox 1 isoform 1 [Homo sapiens]              62   6e-10
gi|10140847 homeobox A2 [Homo sapiens]                                 62   7e-10
gi|24497517 homeobox A5 [Homo sapiens]                                 62   7e-10
gi|33457326 GS homeobox 1 [Homo sapiens]                               62   7e-10
gi|4504465 homeobox B2 [Homo sapiens]                                  62   7e-10
gi|4504469 homeobox B5 [Homo sapiens]                                  61   1e-09
gi|15029506 homeobox D8 [Homo sapiens]                                 61   2e-09

>gi|116734702 homeobox D13 [Homo sapiens]
          Length = 343

 Score =  693 bits (1789), Expect = 0.0
 Identities = 343/343 (100%), Positives = 343/343 (100%)

Query: 1   MSRAGSWDMDGLRADGGGAGGAPASSSSSSVAAAAASGQCRGFLSAPVFAGTHSGRAAAA 60
           MSRAGSWDMDGLRADGGGAGGAPASSSSSSVAAAAASGQCRGFLSAPVFAGTHSGRAAAA
Sbjct: 1   MSRAGSWDMDGLRADGGGAGGAPASSSSSSVAAAAASGQCRGFLSAPVFAGTHSGRAAAA 60

Query: 61  AAAAAAAAAAASGFAYPGTSERTGSSSSSSSSAVVAARPEAPPAKECPAPTPAAAAAAPP 120
           AAAAAAAAAAASGFAYPGTSERTGSSSSSSSSAVVAARPEAPPAKECPAPTPAAAAAAPP
Sbjct: 61  AAAAAAAAAAASGFAYPGTSERTGSSSSSSSSAVVAARPEAPPAKECPAPTPAAAAAAPP 120

Query: 121 SAPALGYGYHFGNGYYSCRMSHGVGLQQNALKSSPHASLGGFPVEKYMDVSGLASSSVPA 180
           SAPALGYGYHFGNGYYSCRMSHGVGLQQNALKSSPHASLGGFPVEKYMDVSGLASSSVPA
Sbjct: 121 SAPALGYGYHFGNGYYSCRMSHGVGLQQNALKSSPHASLGGFPVEKYMDVSGLASSSVPA 180

Query: 181 NEVPARAKEVSFYQGYTSPYQHVPGYIDMVSTFGSGEPRHEAYISMEGYQSWTLANGWNS 240
           NEVPARAKEVSFYQGYTSPYQHVPGYIDMVSTFGSGEPRHEAYISMEGYQSWTLANGWNS
Sbjct: 181 NEVPARAKEVSFYQGYTSPYQHVPGYIDMVSTFGSGEPRHEAYISMEGYQSWTLANGWNS 240

Query: 241 QVYCTKDQPQGSHFWKSSFPGDVALNQPDMCVYRRGRKKRVPYTKLQLKELENEYAINKF 300
           QVYCTKDQPQGSHFWKSSFPGDVALNQPDMCVYRRGRKKRVPYTKLQLKELENEYAINKF
Sbjct: 241 QVYCTKDQPQGSHFWKSSFPGDVALNQPDMCVYRRGRKKRVPYTKLQLKELENEYAINKF 300

Query: 301 INKDKRRRISAATNLSERQVTIWFQNRRVKDKKIVSKLKDTVS 343
           INKDKRRRISAATNLSERQVTIWFQNRRVKDKKIVSKLKDTVS
Sbjct: 301 INKDKRRRISAATNLSERQVTIWFQNRRVKDKKIVSKLKDTVS 343


>gi|24497554 homeobox A13 [Homo sapiens]
          Length = 388

 Score =  272 bits (695), Expect = 4e-73
 Identities = 178/357 (49%), Positives = 217/357 (60%), Gaps = 51/357 (14%)

Query: 14  ADGGG--------AGGAPASSSSSSVAAAAASGQCRGFLS--APVFAGTHS------GRA 57
           A GGG        AGG  + +++++ AAAAA+ QCR  ++  AP+  G  S      G A
Sbjct: 53  AGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAASAYSSAPGEA 112

Query: 58  AAAAAAAAAAAAAASGFAYPGTSERTGSSSSSSSSAVVAARPEAPPAKECPAPTPAAAAA 117
             +AAAAAAAAAAA+  A         +++SSS     A    A  AK+C   +P +AAA
Sbjct: 113 PPSAAAAAAAAAAAAAAA---------AAASSSGGPGPAGPAGAEAAKQC---SPCSAAA 160

Query: 118 APPSAPA-LGYGYHFGNGYYSCRMSHGVGLQQNALKSSPH---ASLGGFPVEKYMDVSGL 173
              S PA L YGY FG+GYY C     +G   NA+KS      A+      +KYMD +G 
Sbjct: 161 QSSSGPAALPYGY-FGSGYYPCAR---MGPHPNAIKSCAQPASAAAAAAFADKYMDTAGP 216

Query: 174 ASSSVPANEVPARAKEVSFY-QGYTS-PYQH---VPGYIDMV---STFGSGEPRHEAY-I 224
           A     A E  +RAKE +FY QGY + PY H   +PGY+DM       G GE RHE   +
Sbjct: 217 A-----AEEFSSRAKEFAFYHQGYAAGPYHHHQPMPGYLDMPVVPGLGGPGESRHEPLGL 271

Query: 225 SMEGYQSWTLANGWNSQVYCTKDQPQGSHFWKSSFPGDVALNQPDMCVYRRGRKKRVPYT 284
            ME YQ W L NGWN Q+YC K+Q Q  H WKS+ P DV  +  D   YRRGRKKRVPYT
Sbjct: 272 PMESYQPWALPNGWNGQMYCPKEQAQPPHLWKSTLP-DVVSHPSDASSYRRGRKKRVPYT 330

Query: 285 KLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKKIVSKLKDT 341
           K+QLKELE EYA NKFI KDKRRRISA TNLSERQVTIWFQNRRVK+KK+++KLK T
Sbjct: 331 KVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKKVINKLKTT 387


>gi|24497536 homeobox C13 [Homo sapiens]
          Length = 330

 Score =  264 bits (675), Expect = 8e-71
 Identities = 149/308 (48%), Positives = 182/308 (59%), Gaps = 37/308 (12%)

Query: 55  GRAAAAAAAAAAAAAAASGFAYPGTSERTGSSSSSSSSA--------VVAARPEAPPAK- 105
           G           A    SG A PG +       SS  ++         V  RP AP    
Sbjct: 30  GGGGGGGGGTGGAGGGCSG-ASPGKAPSMDGLGSSCPASHCRDLLPHPVLGRPPAPLGAP 88

Query: 106 ------ECPAPTPAAAAAAPPSAPA-----LGYGYHFGNGYYSCRMSHGVGLQQNALKSS 154
                 + PAP  A   A PP+ P      LGYGY FG  YY CR+SH V LQQ      
Sbjct: 89  QGAVYTDIPAPEAARQCAPPPAPPTSSSATLGYGYPFGGSYYGCRLSHNVNLQQKPCAYH 148

Query: 155 PHASLGGFPVEKYMDVSGLASSSVPANEVPARAKEVSFYQGYTSPYQHVPGYIDMV---S 211
           P         +KY + SG    ++P +++ +RAKE +FY  + S YQ +PGY+D+     
Sbjct: 149 PG--------DKYPEPSG----ALPGDDLSSRAKEFAFYPSFASSYQAMPGYLDVSVVPG 196

Query: 212 TFGSGEPRHEAYISMEGYQSWTLANGWNSQVYCTKDQPQGSHFWKSSFPGDVALNQPDMC 271
             G  EPRH+A I +EGYQ W L+NGW+SQVYC+K+Q Q +H WKS FP DV   QP++ 
Sbjct: 197 ISGHPEPRHDALIPVEGYQHWALSNGWDSQVYCSKEQSQSAHLWKSPFP-DVVPLQPEVS 255

Query: 272 VYRRGRKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKD 331
            YRRGRKKRVPYTK+QLKELE EYA +KFI K+KRRRISA TNLSERQVTIWFQNRRVK+
Sbjct: 256 SYRRGRKKRVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLSERQVTIWFQNRRVKE 315

Query: 332 KKIVSKLK 339
           KK+VSK K
Sbjct: 316 KKVVSKSK 323


>gi|62865866 homeobox B13 [Homo sapiens]
          Length = 284

 Score =  218 bits (556), Expect = 5e-57
 Identities = 115/247 (46%), Positives = 156/247 (63%), Gaps = 24/247 (9%)

Query: 101 APPAKECPAPTPAAAAAAPPSAPALGYGYHFGNGYYSCRMSHGVGLQQNALK-SSPHASL 159
           A P K+C  P P       P+    GY   FG GYYSCR+S      +++LK  +  A+L
Sbjct: 57  AEPPKQCH-PCPGVPQGTSPAPVPYGY---FGGGYYSCRVS------RSSLKPCAQAATL 106

Query: 160 GGFPVEKYMDVSGLASSSVPANEVPARAKEVSFYQGYTSPYQHVPGYID--MVSTFGS-G 216
             +P E          +     E P+R  E +FY GY   YQ +  Y+D  +V T G+ G
Sbjct: 107 AAYPAE----------TPTAGEEYPSRPTEFAFYPGYPGTYQPMASYLDVSVVQTLGAPG 156

Query: 217 EPRHEAYISMEGYQSWTLANGWNSQVYCTKDQPQGSHFWKSSFPGDVALNQPDMCVYRRG 276
           EPRH++ + ++ YQSW LA GWNSQ+ C  +Q     FWK++F      + PD C +RRG
Sbjct: 157 EPRHDSLLPVDSYQSWALAGGWNSQMCCQGEQNPPGPFWKAAFADSSGQHPPDACAFRRG 216

Query: 277 RKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKKIVS 336
           RKKR+PY+K QL+ELE EYA NKFI KDKRR+ISAAT+LSERQ+TIWFQNRRVK+KK+++
Sbjct: 217 RKKRIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWFQNRRVKEKKVLA 276

Query: 337 KLKDTVS 343
           K+K++ +
Sbjct: 277 KVKNSAT 283


>gi|23510368 homeobox D11 [Homo sapiens]
          Length = 338

 Score = 95.9 bits (237), Expect = 5e-20
 Identities = 102/337 (30%), Positives = 127/337 (37%), Gaps = 108/337 (32%)

Query: 17  GGAGGAPASSSSSSVAAAAASGQCRGFLSAPVFAGTHSGRAAAAAAAAAAAAAAASGFAY 76
           GG GG  A   SS        G   G+  AP +A      AAAAAAAAAAAA  A+    
Sbjct: 77  GGGGGGSAGGGSSGGGPGGGGGGAGGY--APYYA------AAAAAAAAAAAAEEAA---- 124

Query: 77  PGTSERTGSSSSSSSSAVVAARPEAPPAKECP-----APTPAAAAAAPPSAPALGYGYHF 131
                                R   PPA   P     AP P  AA  PP  PA       
Sbjct: 125 -------------------MQRELLPPAGRRPDVLFKAPEPVCAAPGPPHGPAGA----- 160

Query: 132 GNGYYSCRMSHGV---GLQQ--NALKSSPHASLGGFPVEKYMDVSGLASSSVPANEVPAR 186
            + +YS    +G+   G  Q   A    P A              G      PA   P  
Sbjct: 161 ASNFYSAVGRNGILPQGFDQFYEAAPGPPFA--------------GPQPPPPPAPPQPEG 206

Query: 187 AKEVSFYQGYTSPYQHVPGYIDMVSTFGSGEPRHEAYISMEGYQSWTLANGWNSQVYCTK 246
           A +                          G+PR  A              G      CTK
Sbjct: 207 AAD-------------------------KGDPRTGA--------------GGGGGSPCTK 227

Query: 247 DQP--------QGSHFWKSSFPGDVALNQPDMCVY-RRGRKKRVPYTKLQLKELENEYAI 297
             P        +GS       PG+    +    V  +R RKKR PYTK Q++ELE E+  
Sbjct: 228 ATPGSEPKGAAEGSGGDGEGPPGEAGAEKSSSAVAPQRSRKKRCPYTKYQIRELEREFFF 287

Query: 298 NKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKKI 334
           N +INK+KR ++S   NL++RQV IWFQNRR+K+KK+
Sbjct: 288 NVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKL 324


>gi|194353946 homeobox D12 [Homo sapiens]
          Length = 270

 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 37/61 (60%), Positives = 49/61 (80%)

Query: 275 RGRKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKKI 334
           R RKKR PYTK Q+ ELENE+ +N+FIN+ KR+ +S   NLS++QV IWFQNRR+K K++
Sbjct: 201 RARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRV 260

Query: 335 V 335
           V
Sbjct: 261 V 261


>gi|5031759 homeobox A11 [Homo sapiens]
          Length = 313

 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 36/61 (59%), Positives = 49/61 (80%)

Query: 274 RRGRKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKK 333
           +R RKKR PYTK Q++ELE E+  + +INK+KR ++S   NL++RQV IWFQNRR+K+KK
Sbjct: 239 QRTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKK 298

Query: 334 I 334
           I
Sbjct: 299 I 299



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 27/94 (28%), Positives = 39/94 (41%), Gaps = 8/94 (8%)

Query: 15  DGGGAGGAPASSSSSSVAAAAASGQCRGFLSAPVFAGTHSGRAAAAAAAAAAAAAAASGF 74
           D     G PA++++S+ AAAAA+G       AP  + + SG         AAAA      
Sbjct: 162 DKSAEKGPPAATATSAAAAAAATG-------APATSSSDSG-GGGGCRETAAAAEEKERR 213

Query: 75  AYPGTSERTGSSSSSSSSAVVAARPEAPPAKECP 108
             P +S    SSS  +      +  +    K CP
Sbjct: 214 RRPESSSSPESSSGHTEDKAGGSSGQRTRKKRCP 247



 Score = 28.5 bits (62), Expect = 9.1
 Identities = 20/70 (28%), Positives = 27/70 (38%), Gaps = 7/70 (10%)

Query: 44  LSAPVFAGTHSGRAAAAAAAAAAAAAAASGFAYPGTSERTGSSSSSSSSAVVAA------ 97
           L++  + G  S      AA A +AAAAA+    P TS               AA      
Sbjct: 154 LASSDYPGDKSAEKGPPAATATSAAAAAAATGAPATSSSDSGGGGGCRETAAAAEEKERR 213

Query: 98  -RPEAPPAKE 106
            RPE+  + E
Sbjct: 214 RRPESSSSPE 223


>gi|7657166 homeobox C11 [Homo sapiens]
          Length = 304

 Score = 79.7 bits (195), Expect = 3e-15
 Identities = 35/60 (58%), Positives = 48/60 (80%)

Query: 275 RGRKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKKI 334
           R RKKR PY+K Q++ELE E+  N +INK+KR ++S   NL++RQV IWFQNRR+K+KK+
Sbjct: 231 RTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKL 290


>gi|27804315 homeobox C12 [Homo sapiens]
          Length = 282

 Score = 79.3 bits (194), Expect = 5e-15
 Identities = 35/61 (57%), Positives = 48/61 (78%)

Query: 275 RGRKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKKI 334
           R RKKR PY+KLQL ELE E+ +N+FI + +RR +S   NLS++QV IWFQNRR+K K++
Sbjct: 213 RSRKKRKPYSKLQLAELEGEFLVNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKRL 272

Query: 335 V 335
           +
Sbjct: 273 L 273


>gi|194363768 homeobox D9 [Homo sapiens]
          Length = 352

 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 84/330 (25%), Positives = 126/330 (38%), Gaps = 39/330 (11%)

Query: 16  GGGAGGAPASSSSSSVAAAAASGQCRGFLSAPVFAGTHSGRAAAAAAAAAAAAAAASGFA 75
           G GA G PA  +    A AA    C     + VF+ + S     A  +   AAAA SG  
Sbjct: 42  GPGAQGRPAGVADGPAATAAEFASCSFAPRSAVFSASWS-----AVPSQPPAAAAMSGLY 96

Query: 76  YPGTSERTGSSSSSSSSAVVAARPEAPPAKECPAPT--------PAAAAAAPPSAPALGY 127
           +P       ++S+S     V +  E  P     A          P    +  PS PA G 
Sbjct: 97  HPYVPPPPLAASASEPGRYVRSWMEPLPGFPGGAGGGGGGGGGGPGRGPSPGPSGPANGR 156

Query: 128 GYHFGNGYYSCRMSHGVGLQQNALKSSPHASLGGFPVEKYMDVSGLASSSVPANEVPARA 187
            Y             G+  +  A  +   A+            +  +S+S+ ++      
Sbjct: 157 HY-------------GIKPETRAAPAPATAA----------STTSSSSTSLSSSSKRTEC 193

Query: 188 KEVSFYQGYTSPYQHVPGYID---MVSTFGSGEPRHEAYISMEGYQSWTLANGWNSQVYC 244
                 QG + P      ++      +T G+G        +  G  S   A   +    C
Sbjct: 194 SVARESQGSSGPEFSCNSFLQEKAAAATGGTGPGAGIGAATGTGGSSEPSACSDHPIPGC 253

Query: 245 TKDQPQGSHFWKSSFPGDVALNQPDMCVYRRGRKKRVPYTKLQLKELENEYAINKFINKD 304
           +  + +  H        D      +    R  RKKR PYTK Q  ELE E+  N ++ +D
Sbjct: 254 SLKEEEKQHSQPQQQQLDPNNPAANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRD 313

Query: 305 KRRRISAATNLSERQVTIWFQNRRVKDKKI 334
           +R  ++   NL+ERQV IWFQNRR+K KK+
Sbjct: 314 RRYEVARILNLTERQVKIWFQNRRMKMKKM 343



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 35/127 (27%), Positives = 44/127 (34%), Gaps = 21/127 (16%)

Query: 11  GLRADGGGAGGAPASSSSSSVAAAAASGQCRGFLSAPVFAGTHSGRAAAAAAAAAAAAAA 70
           G    GGG GG P    S   +  A               G H G      AA A A AA
Sbjct: 129 GAGGGGGGGGGGPGRGPSPGPSGPA--------------NGRHYGIKPETRAAPAPATAA 174

Query: 71  ASGFAYPGTSERTGSSSSSSSSAVVAARPEAPPAKECPAPT---PAAAAAAPPSAPALGY 127
           ++      +S  + SSSS  +   VA   +     E    +     AAAA   + P  G 
Sbjct: 175 ST----TSSSSTSLSSSSKRTECSVARESQGSSGPEFSCNSFLQEKAAAATGGTGPGAGI 230

Query: 128 GYHFGNG 134
           G   G G
Sbjct: 231 GAATGTG 237


>gi|15029508 homeobox B9 [Homo sapiens]
          Length = 250

 Score = 75.1 bits (183), Expect = 9e-14
 Identities = 34/61 (55%), Positives = 43/61 (70%)

Query: 274 RRGRKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKK 333
           R  RKKR PYTK Q  ELE E+  N ++ +D+R  ++   NLSERQV IWFQNRR+K KK
Sbjct: 183 RSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKK 242

Query: 334 I 334
           +
Sbjct: 243 M 243


>gi|182765442 homeobox A10 isoform a [Homo sapiens]
          Length = 410

 Score = 74.3 bits (181), Expect = 1e-13
 Identities = 74/247 (29%), Positives = 103/247 (41%), Gaps = 35/247 (14%)

Query: 89  SSSSAVVAARPEAPPAKECPAPTPAAAAAAPPSAPALGYGYHFGNGYYSCRMSHGVGLQQ 148
           S+++A +A  P  PP   C   T +      P    L   Y    GY S     G G QQ
Sbjct: 182 SATAAELAPFPRGPPPDGCALGTSSGVPV--PGYFRLSQAYGTAKGYGS----GGGGAQQ 235

Query: 149 NALKSSPHASLG-GFPVEKYMDVSGLASSSVPANEVPARAKEVSFYQGYTSPYQHVPGYI 207
                 P    G GF +        LAS S  A    AR +     +   SP    P   
Sbjct: 236 LGAGPFPAQPPGRGFDLPP-----ALASGSADA----ARKE-----RALDSP----PPPT 277

Query: 208 DMVSTFGSGEPRHEAYISMEGYQSWTLANGWNSQVYCTKDQPQGSHFWKSSFPGDVALNQ 267
               + G  +   EA+ S    +  + A   +S+    KD          S       N 
Sbjct: 278 LACGSGGGSQGDEEAHASSSAAEELSPAPSESSKASPEKD----------SLGNSKGENA 327

Query: 268 PDMCVYRRGRKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNR 327
            +    + GRKKR PYTK Q  ELE E+  N ++ +++R  IS + +L++RQV IWFQNR
Sbjct: 328 ANWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNR 387

Query: 328 RVKDKKI 334
           R+K KK+
Sbjct: 388 RMKLKKM 394


>gi|23510366 homeobox D10 [Homo sapiens]
          Length = 340

 Score = 73.2 bits (178), Expect = 3e-13
 Identities = 33/61 (54%), Positives = 45/61 (73%)

Query: 274 RRGRKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKK 333
           + GRKKR PYTK Q  ELE E+  N ++ +++R  IS + NL++RQV IWFQNRR+K KK
Sbjct: 264 KSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKK 323

Query: 334 I 334
           +
Sbjct: 324 M 324


>gi|24497547 homeobox C9 [Homo sapiens]
          Length = 260

 Score = 73.2 bits (178), Expect = 3e-13
 Identities = 34/67 (50%), Positives = 45/67 (67%)

Query: 274 RRGRKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKK 333
           R  RKKR PYTK Q  ELE E+  N ++ +D+R  ++   NL+ERQV IWFQNRR+K KK
Sbjct: 190 RSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKK 249

Query: 334 IVSKLKD 340
           +  +  D
Sbjct: 250 MNKEKTD 256


>gi|23097236 homeobox A9 [Homo sapiens]
          Length = 272

 Score = 72.8 bits (177), Expect = 4e-13
 Identities = 34/61 (55%), Positives = 43/61 (70%)

Query: 274 RRGRKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKK 333
           R  RKKR PYTK Q  ELE E+  N ++ +D+R  ++   NL+ERQV IWFQNRR+K KK
Sbjct: 204 RSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKK 263

Query: 334 I 334
           I
Sbjct: 264 I 264


>gi|24497533 homeobox C10 [Homo sapiens]
          Length = 342

 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 33/61 (54%), Positives = 44/61 (72%)

Query: 274 RRGRKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKK 333
           + GRKKR PYTK Q  ELE E+  N ++ +++R  IS   NL++RQV IWFQNRR+K KK
Sbjct: 266 KSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKK 325

Query: 334 I 334
           +
Sbjct: 326 M 326


>gi|24497551 homeobox A10 isoform b [Homo sapiens]
          Length = 94

 Score = 71.6 bits (174), Expect = 9e-13
 Identities = 33/69 (47%), Positives = 47/69 (68%)

Query: 266 NQPDMCVYRRGRKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQ 325
           N  +    + GRKKR PYTK Q  ELE E+  N ++ +++R  IS + +L++RQV IWFQ
Sbjct: 10  NAANWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQ 69

Query: 326 NRRVKDKKI 334
           NRR+K KK+
Sbjct: 70  NRRMKLKKM 78


>gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]
          Length = 283

 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 32/82 (39%), Positives = 49/82 (59%), Gaps = 5/82 (6%)

Query: 252 SHFWKSSFPGDVALNQPDMCVYRRGRKKRVPYTKLQLKELENEYAINKFINKDKRRRISA 311
           +H WK  + G     +P+       ++ R  YT+ QL ELE E+  NK+I++ +R  ++ 
Sbjct: 127 AHAWKGQWAGGAYAAEPE-----ENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAV 181

Query: 312 ATNLSERQVTIWFQNRRVKDKK 333
             NL+ER + IWFQNRR+K KK
Sbjct: 182 MLNLTERHIKIWFQNRRMKWKK 203


>gi|89257348 homeo box HB9 [Homo sapiens]
          Length = 401

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 87/328 (26%), Positives = 121/328 (36%), Gaps = 81/328 (24%)

Query: 16  GGGAGGAPASSSSSSVAAAAASGQCRGFLSAPVFAGTHSGRAAAAAAAAAAAAAAA---- 71
           GGG GG  AS  +S        G C    S P  A     RA + +     AA  A    
Sbjct: 42  GGGGGGGGASGGTS--------GSCSPASSEPPAAPADRLRAESPSPPRLLAAHCALLPK 93

Query: 72  SGFAYPGTSERTGSSSSSSSSAVVAARPEAPPAKECPAPTPAAAAAAPPSAPALGYGYHF 131
            GF   G     G +          A P A  A        AAAAAA  +A  L  G H 
Sbjct: 94  PGFL--GAGGGGGGTGGGHGGPHHHAHPGAAAA--------AAAAAAAAAAGGLALGLHP 143

Query: 132 GNGYYSCRMSHGVGLQQNALKSSPHASLGGFPVEKYMDVSGLASSSVPANEVPARAKEVS 191
           G          G GL   A       +L G PV  Y   S  A+++  A + PA +    
Sbjct: 144 GGA------QGGAGLPAQA-------ALYGHPVYGY---SAAAAAAALAGQHPALSYSYP 187

Query: 192 FYQGYTSPYQHVPGYIDMVSTFGSGEPRHEAYISMEGYQSWTLANGWNSQVYCTKDQPQG 251
             QG                      P H A     G  ++ L                 
Sbjct: 188 QVQG--------------------AHPAHPADPIKLGAGTFQL----------------- 210

Query: 252 SHFWKSSFPGDVALNQPDMCVYRRG------RKKRVPYTKLQLKELENEYAINKFINKDK 305
             + ++S  G +    PD     +       R+ R  +T  QL ELE+++ +NK++++ K
Sbjct: 211 DQWLRASTAGMILPKMPDFNSQAQSNLLGKCRRPRTAFTSQQLLELEHQFKLNKYLSRPK 270

Query: 306 RRRISAATNLSERQVTIWFQNRRVKDKK 333
           R  ++ +  L+E QV IWFQNRR+K K+
Sbjct: 271 RFEVATSLMLTETQVKIWFQNRRMKWKR 298



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 28/90 (31%), Positives = 40/90 (44%), Gaps = 23/90 (25%)

Query: 11  GLRADGGGAGGA---------PASSSSSSVAAAAAS----------GQCRGFLSAPVFAG 51
           G    GGG GG          P ++++++ AAAAA+          G  +G    P  A 
Sbjct: 98  GAGGGGGGTGGGHGGPHHHAHPGAAAAAAAAAAAAAAGGLALGLHPGGAQGGAGLPAQAA 157

Query: 52  THS----GRAAAAAAAAAAAAAAASGFAYP 77
            +     G +AAAAAAA A    A  ++YP
Sbjct: 158 LYGHPVYGYSAAAAAAALAGQHPALSYSYP 187


>gi|13273317 homeobox B8 [Homo sapiens]
          Length = 243

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 66/229 (28%), Positives = 98/229 (42%), Gaps = 42/229 (18%)

Query: 130 HFGNGYYSCRMSHGVGLQQNALKSSPHASLGGFPVEKYMDVSGLASSSVPANEVPARAKE 189
           +F N  +S +   G  L+ N         LGG P   Y   SG       + + P++ +E
Sbjct: 4   YFVNSLFS-KYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSG------GSFQHPSQIQE 56

Query: 190 VSFYQG----YTSPYQHVP-------------GY--IDMVSTFGSGEPRHEAYISMEGYQ 230
             FY G     T+PYQ  P             GY  +   S FG+ +P    Y   +   
Sbjct: 57  --FYHGPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCK--- 111

Query: 231 SWTLANGWNSQVYCTKDQPQGSHFWKSSFPGDVALNQPDMCVYRRGRKKRVPYTKLQLKE 290
               A+G   +   ++  P  +  +    P   A         RRGR+    Y++ Q  E
Sbjct: 112 -LAAASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGR-------RRGRQT---YSRYQTLE 160

Query: 291 LENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKKIVSKLK 339
           LE E+  N ++ + +R  +S A  L+ERQV IWFQNRR+K KK  +K K
Sbjct: 161 LEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDK 209


>gi|12056969 homeobox C8 [Homo sapiens]
          Length = 242

 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 66/214 (30%), Positives = 99/214 (46%), Gaps = 33/214 (15%)

Query: 135 YYSCRMSHGVGLQQNALKSSPHASLGGFP-----VEKYMD--VSGLASSSVPANEVPARA 187
           YY CR    VG + +AL   P  S  GF      V+ +     SG+++S    N      
Sbjct: 23  YYDCRFPQSVG-RSHALVYGPGGSAPGFQHASHHVQDFFHHGTSGISNSGYQQNPCSLSC 81

Query: 188 K-EVSFYQGYTSPYQHVPGYIDMVSTFGSGEPRHEAYISMEGYQSWTLANGWNSQVYCTK 246
             + S + GY +        +   S +G+   + EA  S+  Y     +   NS      
Sbjct: 82  HGDASKFYGYEA--------LPRQSLYGA---QQEA--SVVQYPDCKSSANTNSS----- 123

Query: 247 DQPQGSHFWKSSFPGDVALNQPDMCVYRRGRKK-RVPYTKLQLKELENEYAINKFINKDK 305
            + QG H  ++S P   +L  P M  +  GR+  R  Y++ Q  ELE E+  N ++ + +
Sbjct: 124 -EGQG-HLNQNSSP---SLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKR 178

Query: 306 RRRISAATNLSERQVTIWFQNRRVKDKKIVSKLK 339
           R  +S A  L+ERQV IWFQNRR+K KK  +K K
Sbjct: 179 RIEVSHALGLTERQVKIWFQNRRMKWKKENNKDK 212


>gi|18959212 GS homeobox 2 [Homo sapiens]
          Length = 304

 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 29/58 (50%), Positives = 41/58 (70%)

Query: 276 GRKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKK 333
           G++ R  +T  QL ELE E++ N ++++ +R  I+   NLSE+QV IWFQNRRVK KK
Sbjct: 202 GKRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKK 259



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 31/85 (36%), Positives = 34/85 (40%), Gaps = 26/85 (30%)

Query: 14  ADGGGAGGAPASSSSSSVAAAAASGQC--RGFLSAPVFAG-------------------- 51
           A  GGAG     +  S VA AA +       F SAP  A                     
Sbjct: 78  AGSGGAGAGVTGAGGSGVAGAAGALPLLKSQFSSAPGDAQFCPRVNHAHHHHHPPQHHHH 137

Query: 52  ----THSGRAAAAAAAAAAAAAAAS 72
                  G AAAAAAAAAAAAAAA+
Sbjct: 138 HHQPQQPGSAAAAAAAAAAAAAAAA 162



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 15/21 (71%), Positives = 18/21 (85%)

Query: 57  AAAAAAAAAAAAAAASGFAYP 77
           +AAAAAAAAAAAAAA+   +P
Sbjct: 146 SAAAAAAAAAAAAAAAALGHP 166


>gi|91208415 mesenchyme homeobox 1 isoform 3 [Homo sapiens]
          Length = 139

 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 28/60 (46%), Positives = 44/60 (73%)

Query: 275 RGRKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKKI 334
           + RK+R  +TK QL+ELE E+A + ++ + +R  I+   +LSERQV +WFQNRR+K K++
Sbjct: 55  KARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRV 114


>gi|4758710 mesenchyme homeobox 1 isoform 1 [Homo sapiens]
          Length = 254

 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 28/60 (46%), Positives = 44/60 (73%)

Query: 275 RGRKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKKI 334
           + RK+R  +TK QL+ELE E+A + ++ + +R  I+   +LSERQV +WFQNRR+K K++
Sbjct: 170 KARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRV 229


>gi|10140847 homeobox A2 [Homo sapiens]
          Length = 376

 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 28/57 (49%), Positives = 40/57 (70%)

Query: 277 RKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKK 333
           R+ R  YT  QL ELE E+  NK++ + +R  I+A  +L+ERQV +WFQNRR+K K+
Sbjct: 144 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 200


>gi|24497517 homeobox A5 [Homo sapiens]
          Length = 270

 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 69/285 (24%), Positives = 104/285 (36%), Gaps = 71/285 (24%)

Query: 50  AGTHSGRAAAAAAAAAAAAAAASGFAYPGTSERTGSSSSSSSSAVVAARPEAPPAK-ECP 108
           A  HSGR          +    SG  + G+ ER  S ++S+S+A    R   P      P
Sbjct: 38  ASMHSGRYGYGYNGMDLSVGR-SGSGHFGSGERARSYAASASAAPAEPRYSQPATSTHSP 96

Query: 109 APTPAAAAAAPPSAPALGYGYHFGNGYYSCRMSHGVGLQQNALKSSPHASLGGFPVEKYM 168
            P P   +A  PS    G   H G               +N+L +S  AS          
Sbjct: 97  QPDPLPCSAVAPSP---GSDSHHGG--------------KNSLSNSSGASADAGSTH-IS 138

Query: 169 DVSGLASSSVPANEVPARAKEVSFYQGYTSPYQHVPGYIDMVSTFGSGEPRHEAYISMEG 228
              G+ ++S    + PA +++ S                         EP        + 
Sbjct: 139 SREGVGTASGAEEDAPASSEQAS----------------------AQSEPSPAPPAQPQI 176

Query: 229 YQSWTLANGWNSQVYCTKDQPQGSHFWKSSFPGDVALNQPDMCVYRRGRKKRVPYTKLQL 288
           Y        W  +++ + D   G                        G++ R  YT+ Q 
Sbjct: 177 YP-------WMRKLHISHDNIGGPE----------------------GKRARTAYTRYQT 207

Query: 289 KELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKK 333
            ELE E+  N+++ + +R  I+ A  LSERQ+ IWFQNRR+K KK
Sbjct: 208 LELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 252


>gi|33457326 GS homeobox 1 [Homo sapiens]
          Length = 264

 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 29/57 (50%), Positives = 40/57 (70%)

Query: 277 RKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKK 333
           ++ R  +T  QL ELE E+A N ++++ +R  I+   NLSE+QV IWFQNRRVK KK
Sbjct: 148 KRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKK 204


>gi|4504465 homeobox B2 [Homo sapiens]
          Length = 356

 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 28/57 (49%), Positives = 40/57 (70%)

Query: 277 RKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKK 333
           R+ R  YT  QL ELE E+  NK++ + +R  I+A  +L+ERQV +WFQNRR+K K+
Sbjct: 144 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 200


>gi|4504469 homeobox B5 [Homo sapiens]
          Length = 269

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 28/58 (48%), Positives = 40/58 (68%)

Query: 276 GRKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKK 333
           G++ R  YT+ Q  ELE E+  N+++ + +R  I+ A  LSERQ+ IWFQNRR+K KK
Sbjct: 194 GKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 251


>gi|15029506 homeobox D8 [Homo sapiens]
          Length = 290

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 81/299 (27%), Positives = 117/299 (39%), Gaps = 52/299 (17%)

Query: 53  HSGRAAAAAAAAAAAAAAASGFAYPGTSERTGSSSSSSSSAV------VAARPEAPP-AK 105
           +S   AAAAAAAAA  A    +     +   G   +++++A+       A  P APP A 
Sbjct: 10  YSKYKAAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAGFPHAPPQAH 69

Query: 106 ECPAPTPAAAAAAPPSAPALGYGYHFGNGYYSCRMSHGVGLQQNALKSSPHASLGGFPVE 165
             P P+P      PPS    G     G  Y+           Q A    PH      P  
Sbjct: 70  AHPHPSP------PPSGTGCGGREGRGQEYFHPGGGSPAAAYQAAPPPPPHPP----PPP 119

Query: 166 KYMDVSGLASSSVPANEVPARAKEVSFYQGYTSPYQHVPGYIDMVSTFGSGEPRHEAYIS 225
                 G+A    PA           FY           GY ++         R   + +
Sbjct: 120 PPPPCGGIACHGEPAK----------FY-----------GYDNL--------QRQPIFTT 150

Query: 226 MEGYQSWTLANGWNSQVYCTKDQPQGSHFWKSSFPGDV-ALNQPDMCVYRRGRKKRVPYT 284
            +  +     +  +S     +D     H  +SS P  +    +P     RR  + R  Y+
Sbjct: 151 QQEAELVQYPDCKSSSGNIGEDP---DHLNQSSSPSQMFPWMRPQAAPGRR--RGRQTYS 205

Query: 285 KLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKKIVSKLKDTVS 343
           + Q  ELE E+  N ++ + +R  +S A  L+ERQV IWFQNRR+K KK  +K K  VS
Sbjct: 206 RFQTLELEKEFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKKENNKDKFPVS 264



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 39/129 (30%), Positives = 45/129 (34%), Gaps = 28/129 (21%)

Query: 29  SSVAAAAASGQCRGFLSAPVFAGTH-----SGRAAAAAAAAAAAAAAASGF--------A 75
           S   AAAA+    G    P +   H      GR AAAAAA      +A+GF        A
Sbjct: 11  SKYKAAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAGFPHAPPQAHA 70

Query: 76  YP---------GTSERTGSSSS------SSSSAVVAARPEAPPAKECPAPTPAAAAAAPP 120
           +P         G   R G           S +A   A P  PP    P P P     A  
Sbjct: 71  HPHPSPPPSGTGCGGREGRGQEYFHPGGGSPAAAYQAAPPPPPHPPPPPPPPPCGGIACH 130

Query: 121 SAPALGYGY 129
             PA  YGY
Sbjct: 131 GEPAKFYGY 139


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.126    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,538,990
Number of Sequences: 37866
Number of extensions: 763674
Number of successful extensions: 15988
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 634
Number of HSP's successfully gapped in prelim test: 605
Number of HSP's that attempted gapping in prelim test: 7951
Number of HSP's gapped (non-prelim): 4995
length of query: 343
length of database: 18,247,518
effective HSP length: 103
effective length of query: 240
effective length of database: 14,347,320
effective search space: 3443356800
effective search space used: 3443356800
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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