Guide to the Human Genome
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Search of human proteins with 239744403

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239744403 PREDICTED: hypothetical protein XP_002343136 [Homo
sapiens]
         (124 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239755597 PREDICTED: similar to HIG1 domain family, member 1A...   247   2e-66
gi|239750094 PREDICTED: similar to HIG1 domain family, member 1A...   247   2e-66
gi|239744403 PREDICTED: hypothetical protein XP_002343136 [Homo ...   247   2e-66
gi|153085461 HIG1 domain family, member 1A isoform a [Homo sapiens]   179   6e-46
gi|153085470 HIG1 domain family, member 1A isoform b [Homo sapiens]   168   9e-43
gi|153085463 HIG1 domain family, member 1A isoform b [Homo sapiens]   168   9e-43
gi|157817101 HIG1 domain family, member 1C [Homo sapiens]             104   2e-23
gi|7706543 HIG1 hypoxia inducible domain family, member 1B [Homo...    85   2e-17
gi|20270389 HIG1 hypoxia inducible domain family, member 2A [Hom...    62   1e-10
gi|13129044 phosducin-like 3 [Homo sapiens]                            40   4e-04
gi|169202111 PREDICTED: similar to HIG1 domain family, member 2A...    33   0.073
gi|51944950 phosducin-like 2 [Homo sapiens]                            28   1.4  
gi|31542673 chromatin modifying protein 6 [Homo sapiens]               28   2.4  
gi|55953087 G protein-binding protein CRFG [Homo sapiens]              28   2.4  
gi|30794264 glycosylphosphatidylinositol anchored high density l...    27   5.2  
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]         27   5.2  
gi|122937388 MAX gene associated [Homo sapiens]                        26   6.9  
gi|33354279 hypothetical protein LOC55425 [Homo sapiens]               26   6.9  
gi|110349719 titin isoform N2-A [Homo sapiens]                         26   8.9  
gi|11128029 protocadherin gamma subfamily B, 6 isoform 1 precurs...    26   8.9  
gi|14270502 protocadherin gamma subfamily B, 6 isoform 2 precurs...    26   8.9  

>gi|239755597 PREDICTED: similar to HIG1 domain family, member 1A
           [Homo sapiens]
          Length = 124

 Score =  247 bits (630), Expect = 2e-66
 Identities = 124/124 (100%), Positives = 124/124 (100%)

Query: 1   MNLEELEDHVDEFDEEDEHAIEIREILQAVIISTDTDVSLSSYDEAQGSKLIRKAKETPL 60
           MNLEELEDHVDEFDEEDEHAIEIREILQAVIISTDTDVSLSSYDEAQGSKLIRKAKETPL
Sbjct: 1   MNLEELEDHVDEFDEEDEHAIEIREILQAVIISTDTDVSLSSYDEAQGSKLIRKAKETPL 60

Query: 61  VPVGIAGFAALVTYGLYKLKSRGNTQMSLHLIHMRVAAQGFVVGAMTIGMGYSMYREFWA 120
           VPVGIAGFAALVTYGLYKLKSRGNTQMSLHLIHMRVAAQGFVVGAMTIGMGYSMYREFWA
Sbjct: 61  VPVGIAGFAALVTYGLYKLKSRGNTQMSLHLIHMRVAAQGFVVGAMTIGMGYSMYREFWA 120

Query: 121 KPKP 124
           KPKP
Sbjct: 121 KPKP 124


>gi|239750094 PREDICTED: similar to HIG1 domain family, member 1A
           [Homo sapiens]
          Length = 124

 Score =  247 bits (630), Expect = 2e-66
 Identities = 124/124 (100%), Positives = 124/124 (100%)

Query: 1   MNLEELEDHVDEFDEEDEHAIEIREILQAVIISTDTDVSLSSYDEAQGSKLIRKAKETPL 60
           MNLEELEDHVDEFDEEDEHAIEIREILQAVIISTDTDVSLSSYDEAQGSKLIRKAKETPL
Sbjct: 1   MNLEELEDHVDEFDEEDEHAIEIREILQAVIISTDTDVSLSSYDEAQGSKLIRKAKETPL 60

Query: 61  VPVGIAGFAALVTYGLYKLKSRGNTQMSLHLIHMRVAAQGFVVGAMTIGMGYSMYREFWA 120
           VPVGIAGFAALVTYGLYKLKSRGNTQMSLHLIHMRVAAQGFVVGAMTIGMGYSMYREFWA
Sbjct: 61  VPVGIAGFAALVTYGLYKLKSRGNTQMSLHLIHMRVAAQGFVVGAMTIGMGYSMYREFWA 120

Query: 121 KPKP 124
           KPKP
Sbjct: 121 KPKP 124


>gi|239744403 PREDICTED: hypothetical protein XP_002343136 [Homo
           sapiens]
          Length = 124

 Score =  247 bits (630), Expect = 2e-66
 Identities = 124/124 (100%), Positives = 124/124 (100%)

Query: 1   MNLEELEDHVDEFDEEDEHAIEIREILQAVIISTDTDVSLSSYDEAQGSKLIRKAKETPL 60
           MNLEELEDHVDEFDEEDEHAIEIREILQAVIISTDTDVSLSSYDEAQGSKLIRKAKETPL
Sbjct: 1   MNLEELEDHVDEFDEEDEHAIEIREILQAVIISTDTDVSLSSYDEAQGSKLIRKAKETPL 60

Query: 61  VPVGIAGFAALVTYGLYKLKSRGNTQMSLHLIHMRVAAQGFVVGAMTIGMGYSMYREFWA 120
           VPVGIAGFAALVTYGLYKLKSRGNTQMSLHLIHMRVAAQGFVVGAMTIGMGYSMYREFWA
Sbjct: 61  VPVGIAGFAALVTYGLYKLKSRGNTQMSLHLIHMRVAAQGFVVGAMTIGMGYSMYREFWA 120

Query: 121 KPKP 124
           KPKP
Sbjct: 121 KPKP 124


>gi|153085461 HIG1 domain family, member 1A isoform a [Homo sapiens]
          Length = 107

 Score =  179 bits (453), Expect = 6e-46
 Identities = 86/102 (84%), Positives = 94/102 (92%)

Query: 23  IREILQAVIISTDTDVSLSSYDEAQGSKLIRKAKETPLVPVGIAGFAALVTYGLYKLKSR 82
           + EILQA+ +STDT VSL SY+E QGSKLIRKAKE P VPVGIAGFAA+V YGLYKLKSR
Sbjct: 6   VEEILQAITMSTDTGVSLPSYEEDQGSKLIRKAKEAPFVPVGIAGFAAIVAYGLYKLKSR 65

Query: 83  GNTQMSLHLIHMRVAAQGFVVGAMTIGMGYSMYREFWAKPKP 124
           GNT+MS+HLIHMRVAAQGFVVGAMT+GMGYSMYREFWAKPKP
Sbjct: 66  GNTKMSIHLIHMRVAAQGFVVGAMTVGMGYSMYREFWAKPKP 107


>gi|153085470 HIG1 domain family, member 1A isoform b [Homo sapiens]
          Length = 93

 Score =  168 bits (426), Expect = 9e-43
 Identities = 81/93 (87%), Positives = 87/93 (93%)

Query: 32  ISTDTDVSLSSYDEAQGSKLIRKAKETPLVPVGIAGFAALVTYGLYKLKSRGNTQMSLHL 91
           +STDT VSL SY+E QGSKLIRKAKE P VPVGIAGFAA+V YGLYKLKSRGNT+MS+HL
Sbjct: 1   MSTDTGVSLPSYEEDQGSKLIRKAKEAPFVPVGIAGFAAIVAYGLYKLKSRGNTKMSIHL 60

Query: 92  IHMRVAAQGFVVGAMTIGMGYSMYREFWAKPKP 124
           IHMRVAAQGFVVGAMT+GMGYSMYREFWAKPKP
Sbjct: 61  IHMRVAAQGFVVGAMTVGMGYSMYREFWAKPKP 93


>gi|153085463 HIG1 domain family, member 1A isoform b [Homo sapiens]
          Length = 93

 Score =  168 bits (426), Expect = 9e-43
 Identities = 81/93 (87%), Positives = 87/93 (93%)

Query: 32  ISTDTDVSLSSYDEAQGSKLIRKAKETPLVPVGIAGFAALVTYGLYKLKSRGNTQMSLHL 91
           +STDT VSL SY+E QGSKLIRKAKE P VPVGIAGFAA+V YGLYKLKSRGNT+MS+HL
Sbjct: 1   MSTDTGVSLPSYEEDQGSKLIRKAKEAPFVPVGIAGFAAIVAYGLYKLKSRGNTKMSIHL 60

Query: 92  IHMRVAAQGFVVGAMTIGMGYSMYREFWAKPKP 124
           IHMRVAAQGFVVGAMT+GMGYSMYREFWAKPKP
Sbjct: 61  IHMRVAAQGFVVGAMTVGMGYSMYREFWAKPKP 93


>gi|157817101 HIG1 domain family, member 1C [Homo sapiens]
          Length = 97

 Score =  104 bits (259), Expect = 2e-23
 Identities = 48/75 (64%), Positives = 65/75 (86%)

Query: 44  DEAQGSKLIRKAKETPLVPVGIAGFAALVTYGLYKLKSRGNTQMSLHLIHMRVAAQGFVV 103
           DE Q S+LIRK++++P VP+GIAGF  +V+ GLYKLK R + +MS+HLIHMRVAAQGFVV
Sbjct: 12  DEGQLSRLIRKSRDSPFVPIGIAGFVTVVSCGLYKLKYRRDQKMSIHLIHMRVAAQGFVV 71

Query: 104 GAMTIGMGYSMYREF 118
           GA+T+G+ YSMY+++
Sbjct: 72  GAVTLGVLYSMYKDY 86


>gi|7706543 HIG1 hypoxia inducible domain family, member 1B [Homo
           sapiens]
          Length = 99

 Score = 84.7 bits (208), Expect = 2e-17
 Identities = 36/75 (48%), Positives = 55/75 (73%)

Query: 44  DEAQGSKLIRKAKETPLVPVGIAGFAALVTYGLYKLKSRGNTQMSLHLIHMRVAAQGFVV 103
           ++    KL+RK +E+PLVP+G+ G   +  Y +Y+L+SRG+T+MS+HLIH RVAAQ   V
Sbjct: 14  EDCVSEKLLRKTRESPLVPIGLGGCLVVAAYRIYRLRSRGSTKMSIHLIHTRVAAQACAV 73

Query: 104 GAMTIGMGYSMYREF 118
           GA+ +G  Y+MY ++
Sbjct: 74  GAIMLGAVYTMYSDY 88


>gi|20270389 HIG1 hypoxia inducible domain family, member 2A [Homo
           sapiens]
          Length = 106

 Score = 61.6 bits (148), Expect = 1e-10
 Identities = 30/66 (45%), Positives = 43/66 (65%), Gaps = 1/66 (1%)

Query: 45  EAQGSKLIRKAKETPLVPVGIAGFAALVTYGLYKLKSRGNTQMSLHLIHMRVAAQGFVVG 104
           E+   K +RK +E P+VP+G    AA +TYGLY    RGN+Q S  ++  R+AAQGF V 
Sbjct: 33  ESFKEKFVRKTRENPVVPIGCLATAAALTYGLYSF-HRGNSQRSQLMMRTRIAAQGFTVA 91

Query: 105 AMTIGM 110
           A+ +G+
Sbjct: 92  AILLGL 97


>gi|13129044 phosducin-like 3 [Homo sapiens]
          Length = 239

 Score = 40.4 bits (93), Expect = 4e-04
 Identities = 18/23 (78%), Positives = 20/23 (86%)

Query: 1  MNLEELEDHVDEFDEEDEHAIEI 23
          M LEELEDH DEF+EEDE AIE+
Sbjct: 51 MTLEELEDHEDEFNEEDERAIEM 73


>gi|169202111 PREDICTED: similar to HIG1 domain family, member 2A
           [Homo sapiens]
          Length = 103

 Score = 32.7 bits (73), Expect = 0.073
 Identities = 17/61 (27%), Positives = 31/61 (50%)

Query: 54  KAKETPLVPVGIAGFAALVTYGLYKLKSRGNTQMSLHLIHMRVAAQGFVVGAMTIGMGYS 113
           K  + P VP+G    A  +TY L+    +G++Q    +    +  QGF V A+ + + +S
Sbjct: 41  KTCKNPTVPIGCLSKAITLTYSLFYCFYQGHSQCFQLMTRTCITTQGFTVTAILLHLLWS 100

Query: 114 M 114
           +
Sbjct: 101 L 101


>gi|51944950 phosducin-like 2 [Homo sapiens]
          Length = 241

 Score = 28.5 bits (62), Expect = 1.4
 Identities = 12/22 (54%), Positives = 16/22 (72%)

Query: 1  MNLEELEDHVDEFDEEDEHAIE 22
          M L +L++  DEFDEED  A+E
Sbjct: 49 MTLAQLKEAEDEFDEEDMQAVE 70


>gi|31542673 chromatin modifying protein 6 [Homo sapiens]
          Length = 201

 Score = 27.7 bits (60), Expect = 2.4
 Identities = 19/62 (30%), Positives = 29/62 (46%), Gaps = 5/62 (8%)

Query: 1   MNLEELEDHVDEFDEEDEHAIEIREILQAVIISTDTDVSLSSYDEAQGSKLIRKAKETPL 60
           M++EE+E  +DE  E  E+  +I E+L       D D  L        S + ++  E P 
Sbjct: 118 MSIEEVERILDETQEAVEYQRQIDELLAGSFTQEDEDAILEEL-----SAITQEQIELPE 172

Query: 61  VP 62
           VP
Sbjct: 173 VP 174


>gi|55953087 G protein-binding protein CRFG [Homo sapiens]
          Length = 634

 Score = 27.7 bits (60), Expect = 2.4
 Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 4/58 (6%)

Query: 4   EELEDHVDEFDE----EDEHAIEIREILQAVIISTDTDVSLSSYDEAQGSKLIRKAKE 57
           EEL     E+D     EDE  +EIR++ + +       +  S     QG ++ R AK+
Sbjct: 457 EELRTAAGEYDSVSESEDEEMLEIRQLAKQIREKKKLKILESKEKNTQGPRMPRTAKK 514


>gi|30794264 glycosylphosphatidylinositol anchored high density
          lipoprotein binding protein 1 [Homo sapiens]
          Length = 184

 Score = 26.6 bits (57), Expect = 5.2
 Identities = 13/23 (56%), Positives = 16/23 (69%), Gaps = 1/23 (4%)

Query: 4  EELEDH-VDEFDEEDEHAIEIRE 25
          EE EDH  D++DEEDE  +E  E
Sbjct: 28 EEDEDHGPDDYDEEDEDEVEEEE 50


>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
          Length = 3907

 Score = 26.6 bits (57), Expect = 5.2
 Identities = 13/37 (35%), Positives = 24/37 (64%), Gaps = 1/37 (2%)

Query: 1    MNLEELEDHVDEFDEEDEHA-IEIREILQAVIISTDT 36
            ++ E+L+  + E +EE E     +RE+ QA+++S DT
Sbjct: 2130 LSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADT 2166


>gi|122937388 MAX gene associated [Homo sapiens]
          Length = 3114

 Score = 26.2 bits (56), Expect = 6.9
 Identities = 14/56 (25%), Positives = 27/56 (48%)

Query: 2    NLEELEDHVDEFDEEDEHAIEIREILQAVIISTDTDVSLSSYDEAQGSKLIRKAKE 57
            +LE+  DH+DE    +E    ++    + I  + TD      +E  G++  + +KE
Sbjct: 2073 SLEDRGDHLDEECLPEEGCATVKPSEHSCITGSHTDQDYKDVNEEYGARNRKSSKE 2128


>gi|33354279 hypothetical protein LOC55425 [Homo sapiens]
          Length = 340

 Score = 26.2 bits (56), Expect = 6.9
 Identities = 10/23 (43%), Positives = 17/23 (73%)

Query: 35  DTDVSLSSYDEAQGSKLIRKAKE 57
           D D+ ++ +DEAQ   LI+K++E
Sbjct: 304 DKDLKVNRFDEAQKKALIKKSRE 326


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 25.8 bits (55), Expect = 8.9
 Identities = 18/58 (31%), Positives = 26/58 (44%), Gaps = 9/58 (15%)

Query: 5    ELEDHVDEFDEEDEHAIEIREILQAVIISTDTDVSLSSYDEAQGSKLIRKAKETPLVP 62
            E E+  DE +EE E A + RE++Q         V    Y+E+   K+  K  E    P
Sbjct: 9128 EREEGYDEGEEEWEEAYQEREVIQ---------VQKEVYEESHERKVPAKVPEKKAPP 9176


>gi|11128029 protocadherin gamma subfamily B, 6 isoform 1 precursor
           [Homo sapiens]
          Length = 930

 Score = 25.8 bits (55), Expect = 8.9
 Identities = 14/45 (31%), Positives = 28/45 (62%), Gaps = 6/45 (13%)

Query: 3   LEELEDHVDEFDEEDEHAIEIREILQA-----VIISTDTDVSLSS 42
           +E++ DH  +FD+++ H +EI E   A     +  +TD D++++S
Sbjct: 123 IEDVNDHAPQFDKKEIH-LEIFESASAGTRLSLDPATDPDININS 166


>gi|14270502 protocadherin gamma subfamily B, 6 isoform 2 precursor
           [Homo sapiens]
          Length = 820

 Score = 25.8 bits (55), Expect = 8.9
 Identities = 14/45 (31%), Positives = 28/45 (62%), Gaps = 6/45 (13%)

Query: 3   LEELEDHVDEFDEEDEHAIEIREILQA-----VIISTDTDVSLSS 42
           +E++ DH  +FD+++ H +EI E   A     +  +TD D++++S
Sbjct: 123 IEDVNDHAPQFDKKEIH-LEIFESASAGTRLSLDPATDPDININS 166


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,400,283
Number of Sequences: 37866
Number of extensions: 158428
Number of successful extensions: 605
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 588
Number of HSP's gapped (non-prelim): 22
length of query: 124
length of database: 18,247,518
effective HSP length: 89
effective length of query: 35
effective length of database: 14,877,444
effective search space: 520710540
effective search space used: 520710540
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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