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Search of human proteins with 239744064
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin
repeat and PH domain 10 [Homo sapiens]
(684 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repea... 1380 0.0
gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repea... 1377 0.0
gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH do... 1323 0.0
gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens] 1316 0.0
gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH do... 1274 0.0
gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH do... 1273 0.0
gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH do... 1262 0.0
gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activat... 959 0.0
gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens] 791 0.0
gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens] 551 e-156
gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens] 550 e-156
gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens] 449 e-126
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens] 441 e-123
gi|239755300 PREDICTED: similar to centaurin, gamma-like family,... 327 3e-89
gi|239755288 PREDICTED: cyclin Y-like 2 [Homo sapiens] 159 6e-39
gi|239749780 PREDICTED: cyclin Y-like 2 [Homo sapiens] 159 6e-39
gi|239744040 PREDICTED: cyclin Y-like 2 [Homo sapiens] 159 6e-39
gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH doma... 142 8e-34
gi|187608516 centaurin, beta 2 [Homo sapiens] 129 7e-30
gi|7661880 centaurin beta1 [Homo sapiens] 126 6e-29
gi|46094081 development and differentiation enhancing factor 1 [... 122 8e-28
gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domai... 111 3e-24
gi|19923540 ArfGAP with SH3 domain, ankyrin repeat and PH domain... 111 3e-24
gi|206725422 G protein-coupled receptor kinase interacting ArfGA... 111 3e-24
gi|206725420 G protein-coupled receptor kinase interacting ArfGA... 111 3e-24
gi|21237786 G protein-coupled receptor kinase interacting ArfGAP... 111 3e-24
gi|17149830 G protein-coupled receptor kinase interacting ArfGAP... 111 3e-24
gi|17149832 G protein-coupled receptor kinase interacting ArfGAP... 111 3e-24
gi|206725415 G protein-coupled receptor kinase interacting ArfGA... 111 3e-24
gi|146231998 G protein-coupled receptor kinase interactor 1 isof... 107 3e-23
>gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
and PH domain 10 [Homo sapiens]
Length = 684
Score = 1380 bits (3571), Expect = 0.0
Identities = 684/684 (100%), Positives = 684/684 (100%)
Query: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE
Sbjct: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
Query: 61 DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD 120
DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD
Sbjct: 61 DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD 120
Query: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180
VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA
Sbjct: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180
Query: 181 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240
DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP
Sbjct: 181 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240
Query: 241 TPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300
TPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW
Sbjct: 241 TPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300
Query: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360
KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS
Sbjct: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360
Query: 361 NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420
NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT
Sbjct: 361 NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420
Query: 421 WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480
WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV
Sbjct: 421 WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480
Query: 481 DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA 540
DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA
Sbjct: 481 DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA 540
Query: 541 NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL 600
NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL
Sbjct: 541 NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL 600
Query: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLLXGVDVMARDAHGNTALT 660
QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLL GVDVMARDAHGNTALT
Sbjct: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLLXGVDVMARDAHGNTALT 660
Query: 661 YARQASSQECINVLLQYGCPDECV 684
YARQASSQECINVLLQYGCPDECV
Sbjct: 661 YARQASSQECINVLLQYGCPDECV 684
>gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
and PH domain 9 [Homo sapiens]
Length = 684
Score = 1377 bits (3565), Expect = 0.0
Identities = 683/684 (99%), Positives = 683/684 (99%)
Query: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE
Sbjct: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
Query: 61 DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD 120
DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD
Sbjct: 61 DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD 120
Query: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180
VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA
Sbjct: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180
Query: 181 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240
DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP
Sbjct: 181 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240
Query: 241 TPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300
TPVCK SMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW
Sbjct: 241 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300
Query: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360
KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS
Sbjct: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360
Query: 361 NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420
NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT
Sbjct: 361 NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420
Query: 421 WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480
WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV
Sbjct: 421 WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480
Query: 481 DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA 540
DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA
Sbjct: 481 DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA 540
Query: 541 NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL 600
NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL
Sbjct: 541 NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL 600
Query: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLLXGVDVMARDAHGNTALT 660
QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLL GVDVMARDAHGNTALT
Sbjct: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLLXGVDVMARDAHGNTALT 660
Query: 661 YARQASSQECINVLLQYGCPDECV 684
YARQASSQECINVLLQYGCPDECV
Sbjct: 661 YARQASSQECINVLLQYGCPDECV 684
>gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 5 [Homo sapiens]
Length = 686
Score = 1323 bits (3424), Expect = 0.0
Identities = 660/686 (96%), Positives = 666/686 (97%), Gaps = 2/686 (0%)
Query: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
MGNILTC VHPSVSLEFDQQQGSVCPSESEIYEAGA DRMAGAPMAAAVQPAEVTVEVGE
Sbjct: 1 MGNILTCCVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE 60
Query: 61 DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD 120
DLHMH +RD+EMPEALEF+LSANPEASTIFQRNSQTDALEFN SANPEASTIFQRNSQTD
Sbjct: 61 DLHMHHIRDQEMPEALEFSLSANPEASTIFQRNSQTDALEFNPSANPEASTIFQRNSQTD 120
Query: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180
VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTA QHYLTMTIISVTLEIPHHITQRDA
Sbjct: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTASQHYLTMTIISVTLEIPHHITQRDA 180
Query: 181 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240
DRSLSIPDEQLHSFAVSTVHI K RNGGGSLNNYSSSIP TPSTSQEDPQFSVPPTANTP
Sbjct: 181 DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 240
Query: 241 TPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300
TPVCK SMRWSNLFTSEKGS PDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW
Sbjct: 241 TPVCKRSMRWSNLFTSEKGSHPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300
Query: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360
KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS
Sbjct: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360
Query: 361 NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420
NGLSKDMDTGLGDSICFSP ISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT
Sbjct: 361 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420
Query: 421 WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480
WHFEATTYEERDAWVQAIQSQILASLQSC+SSKSKSQLTSQSEAMALQSIQNMRGNAHCV
Sbjct: 421 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480
Query: 481 DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA 540
D ETQNPKWASLNLGVLMCIECSGIHRS GTRLSRVRSLELDDWPVELRKVMSSIGN+LA
Sbjct: 481 DYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 540
Query: 541 NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL 600
NSIWEGSSQGQTKPS+KSTREEKE WIRSKYEEKLFLAPLPCTELSLGQ LLRAT DEDL
Sbjct: 541 NSIWEGSSQGQTKPSVKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQHLLRATADEDL 600
Query: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLL--XGVDVMARDAHGNTA 658
QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVL QLL GVDVMARDAHGNTA
Sbjct: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 660
Query: 659 LTYARQASSQECINVLLQYGCPDECV 684
LTYARQASSQECINVLLQYGCPDECV
Sbjct: 661 LTYARQASSQECINVLLQYGCPDECV 686
>gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens]
Length = 686
Score = 1316 bits (3406), Expect = 0.0
Identities = 656/686 (95%), Positives = 663/686 (96%), Gaps = 2/686 (0%)
Query: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
MGNILTCRVHPSVSLEFDQQQGSVCPSESE YEAGA DRMAGAPMAAAVQPAEVTVEVGE
Sbjct: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESETYEAGARDRMAGAPMAAAVQPAEVTVEVGE 60
Query: 61 DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD 120
DLHMH VRDREMPEALEFNLSANPE+STIFQRNSQT+ALEFN SANPEASTIFQRNSQTD
Sbjct: 61 DLHMHHVRDREMPEALEFNLSANPESSTIFQRNSQTEALEFNPSANPEASTIFQRNSQTD 120
Query: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180
VVEIRRSNCTNHVS RFSQQYS CSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA
Sbjct: 121 VVEIRRSNCTNHVSAVRFSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180
Query: 181 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240
DR+LSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIP TPSTSQEDPQFSVPPTANTP
Sbjct: 181 DRTLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 240
Query: 241 TPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300
TPVCK SMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW
Sbjct: 241 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300
Query: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360
KKKYVTLCSNG+LTYYSSLGDYMKNIHKKEIDL+TSTIKVPGKWPSLATSAC PISSSKS
Sbjct: 301 KKKYVTLCSNGMLTYYSSLGDYMKNIHKKEIDLQTSTIKVPGKWPSLATSACTPISSSKS 360
Query: 361 NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420
NGLSKDMDTGLGDSICFSP ISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT
Sbjct: 361 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420
Query: 421 WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480
WHFEATTYEERDAWVQAIQSQILASLQSC+SSKSKSQLTSQSEAMALQSIQNMRGNAHCV
Sbjct: 421 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480
Query: 481 DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA 540
DCETQNPKWASLNLGVLMCIECSGIHRS G LSRVRSLELDDWPVELRKVMSSI N+LA
Sbjct: 481 DCETQNPKWASLNLGVLMCIECSGIHRSLGPHLSRVRSLELDDWPVELRKVMSSIVNDLA 540
Query: 541 NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL 600
NSIWEGSSQGQTKPS KSTREEKE WIRSKYEEKLFLAPLPCTELSLGQQLLRAT DEDL
Sbjct: 541 NSIWEGSSQGQTKPSEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDL 600
Query: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLL--XGVDVMARDAHGNTA 658
QTAILLLAHGS EEVNETCGEGDGCTALHLACRKGNVVL QLL GVDVMARDAHGNTA
Sbjct: 601 QTAILLLAHGSCEEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 660
Query: 659 LTYARQASSQECINVLLQYGCPDECV 684
LTYARQASSQECINVLLQYGCPDECV
Sbjct: 661 LTYARQASSQECINVLLQYGCPDECV 686
>gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 4 [Homo sapiens]
Length = 663
Score = 1274 bits (3296), Expect = 0.0
Identities = 640/686 (93%), Positives = 646/686 (94%), Gaps = 25/686 (3%)
Query: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGA DRMAGAPMAAAVQPAEVTVEVGE
Sbjct: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE 60
Query: 61 DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD 120
DLHMH VRDREMPEALEFN SANPEASTIFQRNSQTD
Sbjct: 61 DLHMHHVRDREMPEALEFN-----------------------PSANPEASTIFQRNSQTD 97
Query: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180
VVEIRRSNCTNHVST RFSQQYS CSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA
Sbjct: 98 VVEIRRSNCTNHVSTVRFSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 157
Query: 181 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240
DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIP TPSTSQEDPQFSVPPTANTP
Sbjct: 158 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 217
Query: 241 TPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300
TPVCK SMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW
Sbjct: 218 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 277
Query: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360
KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDL+TSTIKVPGKWPSLATSAC PIS+SKS
Sbjct: 278 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLQTSTIKVPGKWPSLATSACTPISTSKS 337
Query: 361 NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420
NGLSKDMDTGLGDSICFSP ISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT
Sbjct: 338 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 397
Query: 421 WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480
WHFEATTYEERDAWVQAIQSQILASLQSC+SSKSKSQLTSQS+AMALQSIQNMRGNAHCV
Sbjct: 398 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSKAMALQSIQNMRGNAHCV 457
Query: 481 DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA 540
DCETQNPKWASLNLGVLMCIECSGIHRS GTRLSRVRSLELDDWPVELRKVMSSIGN+LA
Sbjct: 458 DCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 517
Query: 541 NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL 600
NSIWEGSSQGQTKPS KSTREEKE WIRSKYEEKLFLAPLPCTELSLGQQLLRAT DEDL
Sbjct: 518 NSIWEGSSQGQTKPSEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDL 577
Query: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLL--XGVDVMARDAHGNTA 658
QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVL QLL GVDVMARDAHGNTA
Sbjct: 578 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 637
Query: 659 LTYARQASSQECINVLLQYGCPDECV 684
LTYARQASSQECINVLLQYGCPD+CV
Sbjct: 638 LTYARQASSQECINVLLQYGCPDKCV 663
>gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 8 [Homo sapiens]
Length = 663
Score = 1273 bits (3294), Expect = 0.0
Identities = 641/686 (93%), Positives = 644/686 (93%), Gaps = 25/686 (3%)
Query: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGA DRMAGAPMAAAVQPAEVTVEVGE
Sbjct: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE 60
Query: 61 DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD 120
DLHMH VRDREMPEALEFN SANPEASTIFQRNSQTD
Sbjct: 61 DLHMHHVRDREMPEALEFN-----------------------PSANPEASTIFQRNSQTD 97
Query: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180
VVEIRRSNCTNHVST RFSQQYS CSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA
Sbjct: 98 VVEIRRSNCTNHVSTVRFSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 157
Query: 181 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240
DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIP TPSTSQEDPQFSVPPTANTP
Sbjct: 158 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 217
Query: 241 TPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300
TPVCK SMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW
Sbjct: 218 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 277
Query: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360
KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDL+TSTIKVPGKWPSLATSAC PISSSKS
Sbjct: 278 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLQTSTIKVPGKWPSLATSACTPISSSKS 337
Query: 361 NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420
NGLSKDMDTGLGDSICFSP ISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT
Sbjct: 338 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 397
Query: 421 WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480
WHFEATTYEERDAWVQAIQSQILASLQSC+SSKSKSQLTSQSEAMALQSIQNMRGNAHCV
Sbjct: 398 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 457
Query: 481 DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA 540
DCETQNPKWASLNLGVLMCIECSGIH S GTRLSRVRSLELDDWPVELRKVMSSIGN+LA
Sbjct: 458 DCETQNPKWASLNLGVLMCIECSGIHHSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 517
Query: 541 NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL 600
NSIWEGSSQGQTKPS KSTREEKE WIRSKYEEKLFLAPLPCTELSLGQQLL AT DEDL
Sbjct: 518 NSIWEGSSQGQTKPSEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLWATADEDL 577
Query: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLL--XGVDVMARDAHGNTA 658
QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVL QLL GVDVMARDAHGNTA
Sbjct: 578 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 637
Query: 659 LTYARQASSQECINVLLQYGCPDECV 684
LTYARQASSQECINVLLQYGCPDECV
Sbjct: 638 LTYARQASSQECINVLLQYGCPDECV 663
>gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 7 [Homo sapiens]
Length = 663
Score = 1262 bits (3266), Expect = 0.0
Identities = 635/686 (92%), Positives = 641/686 (93%), Gaps = 25/686 (3%)
Query: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE
Sbjct: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
Query: 61 DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD 120
DLHMH VRDREMPEALEFN SANPEASTIFQRNSQTD
Sbjct: 61 DLHMHHVRDREMPEALEFN-----------------------PSANPEASTIFQRNSQTD 97
Query: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180
VVEIRRSNCTNHVST FSQQYS CSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA
Sbjct: 98 VVEIRRSNCTNHVSTVHFSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 157
Query: 181 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240
DRSLSIPDEQLHSFAVSTVHI K RNGGGSLNNYSSSIP TPSTSQEDPQFSVPPTANTP
Sbjct: 158 DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 217
Query: 241 TPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300
TPVCK SMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW
Sbjct: 218 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 277
Query: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360
KKKYVTLCSNGVLTYYSSLGDYMK IHKKEIDL+TSTIKVPGKWPSLAT AC PISSSKS
Sbjct: 278 KKKYVTLCSNGVLTYYSSLGDYMKYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKS 337
Query: 361 NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420
+GLSKDMDTGLGDSICFSP ISSTT PKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT
Sbjct: 338 DGLSKDMDTGLGDSICFSPSISSTTIPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 397
Query: 421 WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480
WHFEATTYEERDAWVQAIQSQILASLQSC+SSKSKSQLTSQSEAMALQSIQNMRGNAHCV
Sbjct: 398 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 457
Query: 481 DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA 540
DCETQNPKWASLNLGVLMCIECSGIHRS GTRLSRVRSLELDDWPVELRKVMSSIGN+LA
Sbjct: 458 DCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 517
Query: 541 NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL 600
NSIWEGSSQG+TKP+ KSTREEKE WIRSKYEEKLFLAPLPCTELSLGQQLLRAT DEDL
Sbjct: 518 NSIWEGSSQGRTKPTEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDL 577
Query: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLL--XGVDVMARDAHGNTA 658
QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVL QLL GVDVMARDAHGNTA
Sbjct: 578 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 637
Query: 659 LTYARQASSQECINVLLQYGCPDECV 684
LTYARQASSQECINVLLQYGCPDECV
Sbjct: 638 LTYARQASSQECINVLLQYGCPDECV 663
>gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activating
protein 11 [Homo sapiens]
Length = 550
Score = 959 bits (2480), Expect = 0.0
Identities = 489/550 (88%), Positives = 500/550 (90%), Gaps = 27/550 (4%)
Query: 162 MTIISVTLEIPHHITQRDADRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPT 221
MTIISVTLEI HHIT+RDADRSL+I DEQL+SFA STVHI KKRNGGGSLNNYSSSIP T
Sbjct: 1 MTIISVTLEIHHHITERDADRSLTILDEQLYSFAFSTVHITKKRNGGGSLNNYSSSIPLT 60
Query: 222 PSTSQEDPQFSVPPTANTPTPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRA 281
PSTSQED FSVPPTANTPTP+CK SM WSNLFTSEKGSDPDK RKA E+HADTIGSGRA
Sbjct: 61 PSTSQEDLYFSVPPTANTPTPICKQSMGWSNLFTSEKGSDPDKGRKALESHADTIGSGRA 120
Query: 282 IPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVP 341
IPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVP
Sbjct: 121 IPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVP 180
Query: 342 GKWPSLATSACAPISSSKSNGLSKDM---------DTGLGDSICFSPGISSTTSPKLNPP 392
GKWPSLATSACAPISSSKSNGLSKDM D GLGDSICFSP ISSTTSPKLN P
Sbjct: 181 GKWPSLATSACAPISSSKSNGLSKDMEALHMSANSDIGLGDSICFSPSISSTTSPKLNLP 240
Query: 393 PSPHANKKKHLKKKSTNN----------------FMIVSATGQTWHFEATTYEERDAWVQ 436
PSPHANKKKHLKKKSTNN FMIVS TGQT HF+ATTYEERDAWVQ
Sbjct: 241 PSPHANKKKHLKKKSTNNLKDDGLSSTAEEEEEKFMIVSVTGQTCHFKATTYEERDAWVQ 300
Query: 437 AIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGV 496
AIQSQILASLQSC+SSKSKSQLTSQSEAMALQSIQNMRGN+HCVDCETQNPKWASLNLGV
Sbjct: 301 AIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNSHCVDCETQNPKWASLNLGV 360
Query: 497 LMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELANSIWEGSSQGQTKPSI 556
LMCIECSGIHRS GTRLSRVRSLELDDWPVELRKVMSSIGN+LANSIWEGSSQGQTKPSI
Sbjct: 361 LMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSI 420
Query: 557 KSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDLQTAILLLAHGSREEVN 616
+STREEKE WIRSKYE KLFLAPLPCTELSLGQ LLRAT DEDL+TAILLLAHGSREEVN
Sbjct: 421 ESTREEKERWIRSKYEHKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSREEVN 480
Query: 617 ETCGEGDGCTALHLACRKGNVVLEQLL--XGVDVMARDAHGNTALTYARQASSQECINVL 674
ETCGEGDGCTALHLACRKGNVVL QLL GVDVMARDAHGNTALTYARQASSQECINVL
Sbjct: 481 ETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVL 540
Query: 675 LQYGCPDECV 684
LQYGCPDECV
Sbjct: 541 LQYGCPDECV 550
>gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens]
Length = 804
Score = 791 bits (2042), Expect = 0.0
Identities = 406/532 (76%), Positives = 446/532 (83%), Gaps = 34/532 (6%)
Query: 185 SIPDEQLHSFA----VSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240
S+P+ HS VS VHI + NGGGSL++YSSS+P TPSTSQ++ + VPPTANTP
Sbjct: 245 SLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTP 304
Query: 241 TPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KT 299
TPV K S R SNLFTS KGSDPDKE+K E+ AD+IGSGRAIPIKQGMLLKRSGK L K
Sbjct: 305 TPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKE 364
Query: 300 WKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSK 359
WKKKYVTLC NGVLTY+ SL DYM+N+H KEIDL +T+KVPGK P ATSACAPISS K
Sbjct: 365 WKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPK 424
Query: 360 SNGLSKDM---------DTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNN 410
+NGLSKDM DTGLGDS+C SP ISSTTSPKL+PPPSPHAN+KKH +KKST+N
Sbjct: 425 TNGLSKDMSSLHISPNSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSN 484
Query: 411 F------------------MIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCKSS 452
F +IVS TGQTWHFEATTYEERDAWVQAI+SQILASLQSC+SS
Sbjct: 485 FKADGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESS 544
Query: 453 KSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTR 512
K+KS+LTSQSEAMALQSI+NMRGN+HCVDCETQNP WASLNLG LMCIECSGIHR+ GT
Sbjct: 545 KNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTH 604
Query: 513 LSRVRSLELDDWPVELRKVMSSIGNELANSIWEGSSQGQTKPSIKSTREEKEWWIRSKYE 572
LSRVRSL+LDDWPVEL KVMSSIGNELANS+WE SSQG+TKPS+ STREEKE WIR+KYE
Sbjct: 605 LSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYE 664
Query: 573 EKLFLAPLPCTELSLGQQLLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLAC 632
+KLFLAPLPCTELSLGQ LLRAT DEDL+TAILLLAHGSR+EVNETCGEGDG TALHLAC
Sbjct: 665 QKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLAC 724
Query: 633 RKGNVVLEQLL--XGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDE 682
RKGNVVL QLL GVDV ARDAHGNTAL YARQASSQECI+VLLQYGCPDE
Sbjct: 725 RKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDE 776
>gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens]
Length = 911
Score = 551 bits (1419), Expect = e-156
Identities = 299/582 (51%), Positives = 383/582 (65%), Gaps = 84/582 (14%)
Query: 185 SIPDEQLHSF----AVSTVHIMKKRNGGGS-LNNYSSSIPPTPSTSQEDPQFSVPPTANT 239
S+P+ HS ++ VHI + NGGGS ++YSSS+P TPS SQ + + ++T
Sbjct: 301 SLPNSPSHSAVSAASIPAVHINQATNGGGSAFSDYSSSVPSTPSISQRELRIETIAASST 360
Query: 240 PTPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-K 298
PTP+ K S R SN+FTS KG+D D+E+KA E D+IGSGRAIPIKQG+LLKRSGK L K
Sbjct: 361 PTPIRKQSKRRSNIFTSRKGADLDREKKAAECKVDSIGSGRAIPIKQGILLKRSGKSLNK 420
Query: 299 TWKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACA----- 353
WKKKYVTLC NG+LTY+ SL DYM+NIH KEIDL +T+KVPGK AT A A
Sbjct: 421 EWKKKYVTLCDNGLLTYHPSLHDYMQNIHGKEIDLLRTTVKVPGKRLPRATPATAPGTSP 480
Query: 354 ---------------------------------PISSS-----KSNGLSK------DMDT 369
P+SSS + GL + D
Sbjct: 481 RANGLSVERSNTQLGGGTGAPHSASSASLHSERPLSSSAWAGPRPEGLHQRSCSVSSADQ 540
Query: 370 GLGDSICFSPGISS---------TTSPKLNPPPSPHANKKKHLKKKSTNN---------- 410
+ PG+ ++SPKL+PPPSPH+N+KKH +KKST
Sbjct: 541 WSEATTSLPPGMQHPASGPAEVLSSSPKLDPPPSPHSNRKKHRRKKSTGTPRPDGPSSAT 600
Query: 411 --------FMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQS 462
F++VS TGQTWHFEA+T EER+ WVQ++Q+QILASLQ C+S+K K++L +Q+
Sbjct: 601 EEAEESFEFVVVSLTGQTWHFEASTAEERELWVQSVQAQILASLQGCRSAKDKTRLGNQN 660
Query: 463 EAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELD 522
A+A+Q+++ +RGN+ C+DC+ NP WASLNLG LMCIECSGIHR G LSRVRSL+LD
Sbjct: 661 AALAVQAVRTVRGNSFCIDCDAPNPDWASLNLGALMCIECSGIHRHLGAHLSRVRSLDLD 720
Query: 523 DWPVELRKVMSSIGNELANSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPC 582
DWP EL VM+++GN LANS+WEG+ G +KP + REEKE WIR+KYE+KLFLAPLP
Sbjct: 721 DWPPELLAVMTAMGNALANSVWEGALGGYSKPGPDACREEKERWIRAKYEQKLFLAPLPS 780
Query: 583 TELSLGQQLLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQL 642
+++ LGQQLLRA ++DL+ ++LLAHGS+EEVNET G+GDG TALHL+ NVV QL
Sbjct: 781 SDVPLGQQLLRAVVEDDLRLLVMLLAHGSKEEVNETYGDGDGRTALHLSSAMANVVFTQL 840
Query: 643 L--XGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDE 682
L GVDV +RDA G T L YAR+A SQEC ++L+Q+GCP E
Sbjct: 841 LIWYGVDVRSRDARGLTPLAYARRAGSQECADILIQHGCPGE 882
>gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens]
Length = 857
Score = 550 bits (1418), Expect = e-156
Identities = 280/369 (75%), Positives = 307/369 (83%), Gaps = 30/369 (8%)
Query: 334 RTSTIKVPGKWPSLATSACAPISSSKSNGLSKDMDTGLGDSICFSPGISSTTSPKLNPPP 393
R+ ++ +W A + ISS DTGLGDS+C SP ISSTTSPKL+PPP
Sbjct: 471 RSYSVSSADQWSEATVIANSAISS----------DTGLGDSVCSSPSISSTTSPKLDPPP 520
Query: 394 SPHANKKKHLKKKSTNNF------------------MIVSATGQTWHFEATTYEERDAWV 435
SPHAN+KKH +KKST+NF +IVS TGQTWHFEATTYEERDAWV
Sbjct: 521 SPHANRKKHRRKKSTSNFKADGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWV 580
Query: 436 QAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLG 495
QAI+SQILASLQSC+SSK+KS+LTSQSEAMALQSI+NMRGN+HCVDCETQNP WASLNLG
Sbjct: 581 QAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLG 640
Query: 496 VLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELANSIWEGSSQGQTKPS 555
LMCIECSGIHR+ GT LSRVRSL+LDDWPVEL KVMSSIGNELANS+WE SSQG+TKPS
Sbjct: 641 ALMCIECSGIHRNLGTHLSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPS 700
Query: 556 IKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDLQTAILLLAHGSREEV 615
+ STREEKE WIR+KYE+KLFLAPLPCTELSLGQ LLRAT DEDL+TAILLLAHGSR+EV
Sbjct: 701 VDSTREEKERWIRAKYEQKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEV 760
Query: 616 NETCGEGDGCTALHLACRKGNVVLEQLL--XGVDVMARDAHGNTALTYARQASSQECINV 673
NETCGEGDG TALHLACRKGNVVL QLL GVDV ARDAHGNTAL YARQASSQECI+V
Sbjct: 761 NETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDV 820
Query: 674 LLQYGCPDE 682
LLQYGCPDE
Sbjct: 821 LLQYGCPDE 829
Score = 256 bits (654), Expect = 5e-68
Identities = 137/207 (66%), Positives = 157/207 (75%), Gaps = 10/207 (4%)
Query: 185 SIPDEQLHSFA----VSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240
S+P+ HS VS VHI + NGGGSL++YSSS+P TPSTSQ++ + VPPTANTP
Sbjct: 245 SLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTP 304
Query: 241 TPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KT 299
TPV K S R SNLFTS KGSDPDKE+K E+ AD+IGSGRAIPIKQGMLLKRSGK L K
Sbjct: 305 TPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKE 364
Query: 300 WKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSK 359
WKKKYVTLC NGVLTY+ SL DYM+N+H KEIDL +T+KVPGK P ATSACAPISS K
Sbjct: 365 WKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPK 424
Query: 360 SNGLSKDMDTGLGDSICFSPGISSTTS 386
+NGLSKDM S+ SP + TS
Sbjct: 425 TNGLSKDM-----SSLHISPNSGNVTS 446
>gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens]
Length = 836
Score = 449 bits (1155), Expect = e-126
Identities = 259/557 (46%), Positives = 341/557 (61%), Gaps = 65/557 (11%)
Query: 185 SIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTPTP-- 242
S+P HS A + V + + GG ++YSSS+P +P+ + + A TP
Sbjct: 245 SLPSSPSHSAASTPV--AGQASNGGHTSDYSSSLPSSPNVGHRELRAEAAAVAGLSTPGS 302
Query: 243 VCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KTWK 301
+ + + R ++LF + +GSD E+++ ++ +T GSGRAIPIKQ LLKRSG L K WK
Sbjct: 303 LHRAAKRRTSLFANRRGSD--SEKRSLDSRGETTGSGRAIPIKQSFLLKRSGNSLNKEWK 360
Query: 302 KKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKSN 361
KKYVTL SNG L Y+ S+ DY+ + H KE+DL +T+KVPGK P A SA P S+ N
Sbjct: 361 KKYVTLSSNGFLLYHPSINDYIHSTHGKEMDLLRTTVKVPGKRPPRAISAFGP--SASIN 418
Query: 362 GLSKDMDT-GLGDSI-------CFSPGISSTTSP-------------------------- 387
GL KDM T +G+ + SP SS P
Sbjct: 419 GLVKDMSTVQMGEGLEATTPMPSPSPSPSSLQPPPDQTSKHLLKPDRNLARALSTDCTPS 478
Query: 388 ------KLNPPPSPHANKKKHLK--------------KKSTNNFMIVSATGQTWHFEATT 427
PPPSP K++ K ++ F+IVS+TGQTWHFEA +
Sbjct: 479 GDLSPLSREPPPSPMVKKQRRKKLTTPSKTEGSAGQAEEENFEFLIVSSTGQTWHFEAAS 538
Query: 428 YEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNP 487
+EERDAWVQAI+SQILASLQ C+SSK K + SQSEA+A+Q+I+N +GN+ CVDC NP
Sbjct: 539 FEERDAWVQAIESQILASLQCCESSKVKLRTDSQSEAVAIQAIRNAKGNSICVDCGAPNP 598
Query: 488 KWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELANSIWEGS 547
WASLNLG L+CIECSGIHR+ GT LSRVRSL+LDDWP EL V+++IGN+ AN +WE
Sbjct: 599 TWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDWPRELTLVLTAIGNDTANRVWESD 658
Query: 548 SQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDLQTAILLL 607
++G+ KPS S+REE+E WIR+KYE+ LFLAPL +E LG+QL A +D+ T +LLL
Sbjct: 659 TRGRAKPSRDSSREERESWIRAKYEQLLFLAPLSTSEEPLGRQLWAAVQAQDVATVLLLL 718
Query: 608 AHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLL--XGVDVMARDAHGNTALTYARQA 665
AH ++ + + + LHLA +VV+ QLL G DV ARDA G TAL YARQA
Sbjct: 719 AHARHGPLDTSVEDPQLRSPLHLAAELAHVVITQLLLWYGADVAARDAQGRTALFYARQA 778
Query: 666 SSQECINVLLQYGCPDE 682
SQ C ++LLQ+GCP E
Sbjct: 779 GSQLCADILLQHGCPGE 795
>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
Length = 1192
Score = 441 bits (1134), Expect = e-123
Identities = 259/577 (44%), Positives = 341/577 (59%), Gaps = 85/577 (14%)
Query: 185 SIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTPTP-- 242
S+P HS A + V + + GG ++YSSS+P +P+ + + A TP
Sbjct: 581 SLPSSPSHSAASTPV--AGQASNGGHTSDYSSSLPSSPNVGHRELRAEAAAVAGLSTPGS 638
Query: 243 VCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KTWK 301
+ + + R ++LF + +GSD E+++ ++ +T GSGRAIPIKQ LLKRSG L K WK
Sbjct: 639 LHRAAKRRTSLFANRRGSD--SEKRSLDSRGETTGSGRAIPIKQSFLLKRSGNSLNKEWK 696
Query: 302 KKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKSN 361
KKYVTL SNG L Y+ S+ DY+ + H KE+DL +T+KVPGK P A SA P S+ N
Sbjct: 697 KKYVTLSSNGFLLYHPSINDYIHSTHGKEMDLLRTTVKVPGKRPPRAISAFGP--SASIN 754
Query: 362 GLSKDMDT-GLGDSI-------CFSPGISSTTSP-------------------------- 387
GL KDM T +G+ + SP SS P
Sbjct: 755 GLVKDMSTVQMGEGLEATTPMPSPSPSPSSLQPPPDQTSKHLLKPDRNLARALSTDCTPS 814
Query: 388 ------KLNPPPSPHANKKKHLKKKSTNN------------------------------- 410
PPPSP K++ K + +
Sbjct: 815 GDLSPLSREPPPSPMVKKQRRKKLTTPSKTEGSAGQAEAKRKMWKLKSFGSLRNIYKAEE 874
Query: 411 ---FMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMAL 467
F+IVS+TGQTWHFEA ++EERDAWVQAI+SQILASLQ C+SSK K + SQSEA+A+
Sbjct: 875 NFEFLIVSSTGQTWHFEAASFEERDAWVQAIESQILASLQCCESSKVKLRTDSQSEAVAI 934
Query: 468 QSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVE 527
Q+I+N +GN+ CVDC NP WASLNLG L+CIECSGIHR+ GT LSRVRSL+LDDWP E
Sbjct: 935 QAIRNAKGNSICVDCGAPNPTWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDWPRE 994
Query: 528 LRKVMSSIGNELANSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSL 587
L V+++IGN+ AN +WE ++G+ KPS S+REE+E WIR+KYE+ LFLAPL +E L
Sbjct: 995 LTLVLTAIGNDTANRVWESDTRGRAKPSRDSSREERESWIRAKYEQLLFLAPLSTSEEPL 1054
Query: 588 GQQLLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLL--XG 645
G+QL A +D+ T +LLLAH ++ + + + LHLA +VV+ QLL G
Sbjct: 1055 GRQLWAAVQAQDVATVLLLLAHARHGPLDTSVEDPQLRSPLHLAAELAHVVITQLLLWYG 1114
Query: 646 VDVMARDAHGNTALTYARQASSQECINVLLQYGCPDE 682
DV ARDA G TAL YARQA SQ C ++LLQ+GCP E
Sbjct: 1115 ADVAARDAQGRTALFYARQAGSQLCADILLQHGCPGE 1151
>gi|239755300 PREDICTED: similar to centaurin, gamma-like family,
member 1 [Homo sapiens]
Length = 284
Score = 327 bits (837), Expect = 3e-89
Identities = 164/173 (94%), Positives = 166/173 (95%), Gaps = 2/173 (1%)
Query: 514 SRVRSLELDDWPVELRKVMSSIGNELANSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEE 573
SRVRSLELDDWPVELRKVMSSIGN+LANSIWEGSSQGQTKPS KSTREEKE WIRSKYEE
Sbjct: 112 SRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSEKSTREEKERWIRSKYEE 171
Query: 574 KLFLAPLPCTELSLGQQLLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACR 633
KLFLAPLPCT+LSLGQQLLRAT DEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACR
Sbjct: 172 KLFLAPLPCTDLSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACR 231
Query: 634 KGNVVLEQLL--XGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDECV 684
KGNVVL QLL GVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDECV
Sbjct: 232 KGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDECV 284
Score = 39.7 bits (91), Expect = 0.009
Identities = 18/18 (100%), Positives = 18/18 (100%)
Query: 178 RDADRSLSIPDEQLHSFA 195
RDADRSLSIPDEQLHSFA
Sbjct: 94 RDADRSLSIPDEQLHSFA 111
>gi|239755288 PREDICTED: cyclin Y-like 2 [Homo sapiens]
Length = 362
Score = 159 bits (403), Expect = 6e-39
Identities = 102/200 (51%), Positives = 117/200 (58%), Gaps = 28/200 (14%)
Query: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
MGNILTC V P S Q QG VC ESEIYEA A D +AG P+AAAV+P EVT GE
Sbjct: 1 MGNILTCCVCPRASPGLHQHQGLVCHCESEIYEAAAGDLIAGVPVAAAVEPGEVTFVAGE 60
Query: 61 DLHMHQVRDREMPE--ALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQ 118
LHMH + +REMPE LE N S +P+ASTIF R SQTD
Sbjct: 61 GLHMHHICEREMPEDIPLEPNPSDHPKASTIFLRKSQTD--------------------- 99
Query: 119 TDVVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISV--TLEIPHHIT 176
V+ ++ VSTE F+QQYSSCSTIFLDDS A Q +LTMT+ S I +
Sbjct: 100 ---VQEKKKKQLCKVSTEHFTQQYSSCSTIFLDDSIASQPHLTMTLKSXCDLGTILSYQA 156
Query: 177 QRDADRSLSIPDEQLHSFAV 196
+RDA RSL I DEQLH V
Sbjct: 157 KRDAHRSLGIFDEQLHPLTV 176
>gi|239749780 PREDICTED: cyclin Y-like 2 [Homo sapiens]
Length = 362
Score = 159 bits (403), Expect = 6e-39
Identities = 102/200 (51%), Positives = 117/200 (58%), Gaps = 28/200 (14%)
Query: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
MGNILTC V P S Q QG VC ESEIYEA A D +AG P+AAAV+P EVT GE
Sbjct: 1 MGNILTCCVCPRASPGLHQHQGLVCHCESEIYEAAAGDLIAGVPVAAAVEPGEVTFVAGE 60
Query: 61 DLHMHQVRDREMPE--ALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQ 118
LHMH + +REMPE LE N S +P+ASTIF R SQTD
Sbjct: 61 GLHMHHICEREMPEDIPLEPNPSDHPKASTIFLRKSQTD--------------------- 99
Query: 119 TDVVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISV--TLEIPHHIT 176
V+ ++ VSTE F+QQYSSCSTIFLDDS A Q +LTMT+ S I +
Sbjct: 100 ---VQEKKKKQLCKVSTEHFTQQYSSCSTIFLDDSIASQPHLTMTLKSXCDLGTILSYQA 156
Query: 177 QRDADRSLSIPDEQLHSFAV 196
+RDA RSL I DEQLH V
Sbjct: 157 KRDAHRSLGIFDEQLHPLTV 176
>gi|239744040 PREDICTED: cyclin Y-like 2 [Homo sapiens]
Length = 362
Score = 159 bits (403), Expect = 6e-39
Identities = 102/200 (51%), Positives = 117/200 (58%), Gaps = 28/200 (14%)
Query: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
MGNILTC V P S Q QG VC ESEIYEA A D +AG P+AAAV+P EVT GE
Sbjct: 1 MGNILTCCVCPRASPGLHQHQGLVCHCESEIYEAAAGDLIAGVPVAAAVEPGEVTFVAGE 60
Query: 61 DLHMHQVRDREMPE--ALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQ 118
LHMH + +REMPE LE N S +P+ASTIF R SQTD
Sbjct: 61 GLHMHHICEREMPEDIPLEPNPSDHPKASTIFLRKSQTD--------------------- 99
Query: 119 TDVVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISV--TLEIPHHIT 176
V+ ++ VSTE F+QQYSSCSTIFLDDS A Q +LTMT+ S I +
Sbjct: 100 ---VQEKKKKQLCKVSTEHFTQQYSSCSTIFLDDSIASQPHLTMTLKSXCDLGTILSYQA 156
Query: 177 QRDADRSLSIPDEQLHSFAV 196
+RDA RSL I DEQLH V
Sbjct: 157 KRDAHRSLGIFDEQLHPLTV 176
>gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH domains
3 [Homo sapiens]
Length = 834
Score = 142 bits (359), Expect = 8e-34
Identities = 80/192 (41%), Positives = 113/192 (58%), Gaps = 22/192 (11%)
Query: 411 FMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQ----SCKS-------SKSKSQLT 459
F ++S T ++ +A + + R AWVQA+Q+ I ++ + SC S S S S +
Sbjct: 332 FEVLSPT-KSCMLQADSEKLRQAWVQAVQASIASAYRESPDSCYSERLDRTASPSTSSID 390
Query: 460 SQSEAM--------ALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGT 511
S ++ LQ +Q++ GN+ C DC +P+WAS+NLGVL+CIECSGIHRS G
Sbjct: 391 SATDTRERGVKGESVLQRVQSVAGNSQCGDCGQPDPRWASINLGVLLCIECSGIHRSLGV 450
Query: 512 RLSRVRSLELDDWPVELRKVMSSIGNELANSIWEGSSQ--GQTKPSIKSTREEKEWWIRS 569
S+VRSL LD W EL K+M +GN N I+E + G KP+ S+R++KE WI+
Sbjct: 451 HCSKVRSLTLDSWEPELLKLMCELGNSAVNQIYEAQCEGAGSRKPTASSSRQDKEAWIKD 510
Query: 570 KYEEKLFLAPLP 581
KY EK FL P
Sbjct: 511 KYVEKKFLRKAP 522
>gi|187608516 centaurin, beta 2 [Homo sapiens]
Length = 778
Score = 129 bits (325), Expect = 7e-30
Identities = 75/186 (40%), Positives = 109/186 (58%), Gaps = 21/186 (11%)
Query: 411 FMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSC---------KSSKSKSQLTSQ 461
F +VS T ++ +A + + R AW++A+Q+ I + + KSS S L S
Sbjct: 330 FEVVSPT-KSCMLQADSEKLRQAWIKAVQTSIATAYREKGDESEKLDKKSSPSTGSLDSG 388
Query: 462 SEAM--------ALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRL 513
+E+ ALQ +Q + GNA C DC +P+WAS+NLG+ +CIECSGIHRS G
Sbjct: 389 NESKEKLLKGESALQRVQCIPGNASCCDCGLADPRWASINLGITLCIECSGIHRSLGVHF 448
Query: 514 SRVRSLELDDWPVELRKVMSSIGNELANSIWEGS--SQGQTKPSIKSTREEKEWWIRSKY 571
S+VRSL LD W EL K+M +GN++ N ++E + G KP R+EKE +IR+KY
Sbjct: 449 SKVRSLTLDTWEPELLKLMCELGNDVINRVYEANVEKMGIKKPQ-PGQRQEKEAYIRAKY 507
Query: 572 EEKLFL 577
E+ F+
Sbjct: 508 VERKFV 513
>gi|7661880 centaurin beta1 [Homo sapiens]
Length = 740
Score = 126 bits (317), Expect = 6e-29
Identities = 73/194 (37%), Positives = 99/194 (51%), Gaps = 26/194 (13%)
Query: 414 VSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCKSSKSK-------------SQLTS 460
V +T ++ +A + WV A+QS I ++ + S S T
Sbjct: 331 VVSTSKSCLLQADSERLLQLWVSAVQSSIASAFSQARLDDSPRGPGQGSGHLAIGSAATL 390
Query: 461 QSEAMA-----------LQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSF 509
S MA + +Q++ GNA C DC P+WAS+NLGV +CI+CSGIHRS
Sbjct: 391 GSGGMARGREPGGVGHVVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSL 450
Query: 510 GTRLSRVRSLELDDWPVELRKVMSSIGNELANSIWEGSSQGQT--KPSIKSTREEKEWWI 567
G S+VRSL LD W EL K+M +GN + N I+E + KP +R+EKE WI
Sbjct: 451 GVHFSKVRSLTLDSWEPELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWI 510
Query: 568 RSKYEEKLFLAPLP 581
+KY EK FL LP
Sbjct: 511 HAKYVEKKFLTKLP 524
Score = 33.5 bits (75), Expect = 0.67
Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 6/86 (6%)
Query: 591 LLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLLX--GVDV 648
L++AT L LL +G+ ++ G G LH A G+ L L G D+
Sbjct: 611 LIQATAANSLLACEFLLQNGANVNQADSAGRGP----LHHATILGHTGLACLFLKRGADL 666
Query: 649 MARDAHGNTALTYARQASSQECINVL 674
ARD+ G LT A + ++ + + +L
Sbjct: 667 GARDSEGRDPLTIAMETANADIVTLL 692
>gi|46094081 development and differentiation enhancing factor 1
[Homo sapiens]
Length = 1129
Score = 122 bits (307), Expect = 8e-28
Identities = 92/296 (31%), Positives = 141/296 (47%), Gaps = 28/296 (9%)
Query: 395 PHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAI---QSQILASLQSCKS 451
P+A KK S N +T+HF+A ++ AW+ + + + L +
Sbjct: 377 PNAEDKKSFDLISHN---------RTYHFQAEDEQDYVAWISVLTNSKEEALTMAFRGEQ 427
Query: 452 SKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGT 511
S ++ L ++A+ ++ +Q + GN C DC + P W S NLG+L CIECSGIHR G
Sbjct: 428 SAGENSLEDLTKAI-IEDVQRLPGNDICCDCGSSEPTWLSTNLGILTCIECSGIHREMGV 486
Query: 512 RLSRVRSLELDDWPVELRKVMSSIGNELANSIWEGSSQGQT-KPSIKSTREEKEWWIRSK 570
+SR++SLELD + ++GN N I E + + KP+ S ++ +I +K
Sbjct: 487 HISRIQSLELDKLGTSELLLAKNVGNNSFNDIMEANLPSPSPKPTPSSDMTVRKEYITAK 546
Query: 571 YEEKLFLAPLPCTELSLGQQLLRATTDEDLQTAILLLAHGSR--EEVNETCGEGDGCTAL 628
Y + F T + +LL A DL I + A G E + E G+ G TAL
Sbjct: 547 YVDHRFSRKTCSTSSAKLNELLEAIKSRDLLALIQVYAEGVELMEPLLEP-GQELGETAL 605
Query: 629 HLACRKGNVVLEQLLXGVDVMARD--------AHGNTALTYARQASSQECINVLLQ 676
HLA R + + L VD + ++ A GNT L Y S EC+ +LL+
Sbjct: 606 HLAVRTAD---QTSLHLVDFLVQNCGNLDKQTALGNTVLHYCSMYSKPECLKLLLR 658
>gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
isoform b [Homo sapiens]
Length = 894
Score = 111 bits (277), Expect = 3e-24
Identities = 87/279 (31%), Positives = 132/279 (47%), Gaps = 26/279 (9%)
Query: 419 QTWHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEA-----------MAL 467
+T+HF+A E +AWV +Q+ +L S + + S A + +
Sbjct: 361 RTYHFQAEDEHECEAWVSVLQNSKDEALSSAFLGEPSAGPGSWGSAGHDGEPHDLTKLLI 420
Query: 468 QSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELD-DWPV 526
+++ GN+ C DC +P W S NLGVL CI+CSG+HR G R SR++SL LD P
Sbjct: 421 AEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPS 480
Query: 527 ELRKVMSSIGNELANSIWEGS--SQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTE 584
EL + ++GN N + E S G KPS +S + +I +KY E F CT
Sbjct: 481 ELLLAL-NMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHRFAR--RCTP 537
Query: 585 LSLGQQLLRATTDEDLQTAILLLAHGS--REEVNETCGEGDGCTALHLACRKGNVVLEQL 642
Q+L A + DL + + A+G + + + LHLA + N L
Sbjct: 538 EP--QRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPL 595
Query: 643 L-----XGVDVMARDAHGNTALTYARQASSQECINVLLQ 676
+ G + A+ A GNTAL YA + +C+ +LL+
Sbjct: 596 VDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLK 634
>gi|19923540 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
isoform a [Homo sapiens]
Length = 903
Score = 111 bits (277), Expect = 3e-24
Identities = 87/279 (31%), Positives = 132/279 (47%), Gaps = 26/279 (9%)
Query: 419 QTWHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEA-----------MAL 467
+T+HF+A E +AWV +Q+ +L S + + S A + +
Sbjct: 370 RTYHFQAEDEHECEAWVSVLQNSKDEALSSAFLGEPSAGPGSWGSAGHDGEPHDLTKLLI 429
Query: 468 QSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELD-DWPV 526
+++ GN+ C DC +P W S NLGVL CI+CSG+HR G R SR++SL LD P
Sbjct: 430 AEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPS 489
Query: 527 ELRKVMSSIGNELANSIWEGS--SQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTE 584
EL + ++GN N + E S G KPS +S + +I +KY E F CT
Sbjct: 490 ELLLAL-NMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHRFAR--RCTP 546
Query: 585 LSLGQQLLRATTDEDLQTAILLLAHGS--REEVNETCGEGDGCTALHLACRKGNVVLEQL 642
Q+L A + DL + + A+G + + + LHLA + N L
Sbjct: 547 EP--QRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPL 604
Query: 643 L-----XGVDVMARDAHGNTALTYARQASSQECINVLLQ 676
+ G + A+ A GNTAL YA + +C+ +LL+
Sbjct: 605 VDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLK 643
>gi|206725422 G protein-coupled receptor kinase interacting ArfGAP 2
isoform 5 [Homo sapiens]
Length = 729
Score = 111 bits (277), Expect = 3e-24
Identities = 71/222 (31%), Positives = 111/222 (50%), Gaps = 19/222 (8%)
Query: 471 QNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRK 530
+ +R + C DC +P WAS+N G +C EC +HRS G +S+VR L+ WP L +
Sbjct: 3 KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62
Query: 531 VMSSIGNELANSIWEGS-------SQGQTKPSIK-STREEKEWWIRSKYEEKLFLAPLPC 582
++ ++ N ANSIWE S G+ K + + K +IR+KY+ F+ LPC
Sbjct: 63 MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122
Query: 583 ------TELSLGQQLLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 636
T L +QL + +L+T + LL+ G++ G T LH+A + G
Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179
Query: 637 VVLEQLL--XGVDVMARDAHGNTALTYARQASSQECINVLLQ 676
++ +LL G D +D+ G T + YARQ E L++
Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221
>gi|206725420 G protein-coupled receptor kinase interacting ArfGAP 2
isoform 6 [Homo sapiens]
Length = 681
Score = 111 bits (277), Expect = 3e-24
Identities = 71/222 (31%), Positives = 111/222 (50%), Gaps = 19/222 (8%)
Query: 471 QNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRK 530
+ +R + C DC +P WAS+N G +C EC +HRS G +S+VR L+ WP L +
Sbjct: 3 KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62
Query: 531 VMSSIGNELANSIWEGS-------SQGQTKPSIK-STREEKEWWIRSKYEEKLFLAPLPC 582
++ ++ N ANSIWE S G+ K + + K +IR+KY+ F+ LPC
Sbjct: 63 MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122
Query: 583 ------TELSLGQQLLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 636
T L +QL + +L+T + LL+ G++ G T LH+A + G
Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179
Query: 637 VVLEQLL--XGVDVMARDAHGNTALTYARQASSQECINVLLQ 676
++ +LL G D +D+ G T + YARQ E L++
Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221
>gi|21237786 G protein-coupled receptor kinase interacting ArfGAP 2
isoform 3 [Homo sapiens]
Length = 679
Score = 111 bits (277), Expect = 3e-24
Identities = 71/222 (31%), Positives = 111/222 (50%), Gaps = 19/222 (8%)
Query: 471 QNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRK 530
+ +R + C DC +P WAS+N G +C EC +HRS G +S+VR L+ WP L +
Sbjct: 3 KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62
Query: 531 VMSSIGNELANSIWEGS-------SQGQTKPSIK-STREEKEWWIRSKYEEKLFLAPLPC 582
++ ++ N ANSIWE S G+ K + + K +IR+KY+ F+ LPC
Sbjct: 63 MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122
Query: 583 ------TELSLGQQLLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 636
T L +QL + +L+T + LL+ G++ G T LH+A + G
Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179
Query: 637 VVLEQLL--XGVDVMARDAHGNTALTYARQASSQECINVLLQ 676
++ +LL G D +D+ G T + YARQ E L++
Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221
>gi|17149830 G protein-coupled receptor kinase interacting ArfGAP 2
isoform 1 [Homo sapiens]
Length = 759
Score = 111 bits (277), Expect = 3e-24
Identities = 71/222 (31%), Positives = 111/222 (50%), Gaps = 19/222 (8%)
Query: 471 QNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRK 530
+ +R + C DC +P WAS+N G +C EC +HRS G +S+VR L+ WP L +
Sbjct: 3 KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62
Query: 531 VMSSIGNELANSIWEGS-------SQGQTKPSIK-STREEKEWWIRSKYEEKLFLAPLPC 582
++ ++ N ANSIWE S G+ K + + K +IR+KY+ F+ LPC
Sbjct: 63 MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122
Query: 583 ------TELSLGQQLLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 636
T L +QL + +L+T + LL+ G++ G T LH+A + G
Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179
Query: 637 VVLEQLL--XGVDVMARDAHGNTALTYARQASSQECINVLLQ 676
++ +LL G D +D+ G T + YARQ E L++
Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221
>gi|17149832 G protein-coupled receptor kinase interacting ArfGAP 2
isoform 2 [Homo sapiens]
Length = 631
Score = 111 bits (277), Expect = 3e-24
Identities = 71/222 (31%), Positives = 111/222 (50%), Gaps = 19/222 (8%)
Query: 471 QNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRK 530
+ +R + C DC +P WAS+N G +C EC +HRS G +S+VR L+ WP L +
Sbjct: 3 KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62
Query: 531 VMSSIGNELANSIWEGS-------SQGQTKPSIK-STREEKEWWIRSKYEEKLFLAPLPC 582
++ ++ N ANSIWE S G+ K + + K +IR+KY+ F+ LPC
Sbjct: 63 MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122
Query: 583 ------TELSLGQQLLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 636
T L +QL + +L+T + LL+ G++ G T LH+A + G
Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179
Query: 637 VVLEQLL--XGVDVMARDAHGNTALTYARQASSQECINVLLQ 676
++ +LL G D +D+ G T + YARQ E L++
Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221
>gi|206725415 G protein-coupled receptor kinase interacting ArfGAP 2
isoform 4 [Homo sapiens]
Length = 471
Score = 111 bits (277), Expect = 3e-24
Identities = 71/222 (31%), Positives = 111/222 (50%), Gaps = 19/222 (8%)
Query: 471 QNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRK 530
+ +R + C DC +P WAS+N G +C EC +HRS G +S+VR L+ WP L +
Sbjct: 3 KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62
Query: 531 VMSSIGNELANSIWEGS-------SQGQTKPSIK-STREEKEWWIRSKYEEKLFLAPLPC 582
++ ++ N ANSIWE S G+ K + + K +IR+KY+ F+ LPC
Sbjct: 63 MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122
Query: 583 ------TELSLGQQLLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 636
T L +QL + +L+T + LL+ G++ G T LH+A + G
Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179
Query: 637 VVLEQLL--XGVDVMARDAHGNTALTYARQASSQECINVLLQ 676
++ +LL G D +D+ G T + YARQ E L++
Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221
>gi|146231998 G protein-coupled receptor kinase interactor 1 isoform
1 [Homo sapiens]
Length = 770
Score = 107 bits (268), Expect = 3e-23
Identities = 70/214 (32%), Positives = 107/214 (50%), Gaps = 19/214 (8%)
Query: 479 CVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNE 538
C DC +P WAS++ GVL+C EC +HRS G +S V+ L WP L +++ ++ +
Sbjct: 11 CADCSAPDPGWASISRGVLVCDECCSVHRSLGRHISIVKHLRHSAWPPTLLQMVHTLASN 70
Query: 539 LANSIWEGS-------SQGQTKPSIK-STREEKEWWIRSKYEEKLFLAPLPC------TE 584
ANSIWE S G+ K + + K +IR+KY+ F+ LPC T
Sbjct: 71 GANSIWEHSLLDPAQVQSGRRKANPQDKVHPIKSEFIRAKYQMLAFVHKLPCRDDDGVTA 130
Query: 585 LSLGQQLLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLL- 643
L +QL + +L+T + LL+ G++ G T LH+A + G + +LL
Sbjct: 131 KDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGTTPLHVAAKAGQTLQAELLV 187
Query: 644 -XGVDVMARDAHGNTALTYARQASSQECINVLLQ 676
G D + D +G T + YARQA E L++
Sbjct: 188 VYGADPGSPDVNGRTPIDYARQAGHHELAERLVE 221
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.127 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,806,270
Number of Sequences: 37866
Number of extensions: 1234174
Number of successful extensions: 5131
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 131
Number of HSP's successfully gapped in prelim test: 198
Number of HSP's that attempted gapping in prelim test: 4345
Number of HSP's gapped (non-prelim): 813
length of query: 684
length of database: 18,247,518
effective HSP length: 109
effective length of query: 575
effective length of database: 14,120,124
effective search space: 8119071300
effective search space used: 8119071300
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.