Guide to the Human Genome
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Search of human proteins with 239744064

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin
repeat and PH domain 10 [Homo sapiens]
         (684 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repea...  1380   0.0  
gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repea...  1377   0.0  
gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH do...  1323   0.0  
gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens]   1316   0.0  
gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH do...  1274   0.0  
gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH do...  1273   0.0  
gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH do...  1262   0.0  
gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activat...   959   0.0  
gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens]               791   0.0  
gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens]              551   e-156
gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens]               550   e-156
gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens]           449   e-126
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]         441   e-123
gi|239755300 PREDICTED: similar to centaurin, gamma-like family,...   327   3e-89
gi|239755288 PREDICTED: cyclin Y-like 2 [Homo sapiens]                159   6e-39
gi|239749780 PREDICTED: cyclin Y-like 2 [Homo sapiens]                159   6e-39
gi|239744040 PREDICTED: cyclin Y-like 2 [Homo sapiens]                159   6e-39
gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH doma...   142   8e-34
gi|187608516 centaurin, beta 2 [Homo sapiens]                         129   7e-30
gi|7661880 centaurin beta1 [Homo sapiens]                             126   6e-29
gi|46094081 development and differentiation enhancing factor 1 [...   122   8e-28
gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domai...   111   3e-24
gi|19923540 ArfGAP with SH3 domain, ankyrin repeat and PH domain...   111   3e-24
gi|206725422 G protein-coupled receptor kinase interacting ArfGA...   111   3e-24
gi|206725420 G protein-coupled receptor kinase interacting ArfGA...   111   3e-24
gi|21237786 G protein-coupled receptor kinase interacting ArfGAP...   111   3e-24
gi|17149830 G protein-coupled receptor kinase interacting ArfGAP...   111   3e-24
gi|17149832 G protein-coupled receptor kinase interacting ArfGAP...   111   3e-24
gi|206725415 G protein-coupled receptor kinase interacting ArfGA...   111   3e-24
gi|146231998 G protein-coupled receptor kinase interactor 1 isof...   107   3e-23

>gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
           and PH domain 10 [Homo sapiens]
          Length = 684

 Score = 1380 bits (3571), Expect = 0.0
 Identities = 684/684 (100%), Positives = 684/684 (100%)

Query: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
           MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE
Sbjct: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60

Query: 61  DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD 120
           DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD
Sbjct: 61  DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD 120

Query: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180
           VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA
Sbjct: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180

Query: 181 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240
           DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP
Sbjct: 181 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240

Query: 241 TPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300
           TPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW
Sbjct: 241 TPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300

Query: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360
           KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS
Sbjct: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360

Query: 361 NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420
           NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT
Sbjct: 361 NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420

Query: 421 WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480
           WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV
Sbjct: 421 WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480

Query: 481 DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA 540
           DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA
Sbjct: 481 DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA 540

Query: 541 NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL 600
           NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL
Sbjct: 541 NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL 600

Query: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLLXGVDVMARDAHGNTALT 660
           QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLL GVDVMARDAHGNTALT
Sbjct: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLLXGVDVMARDAHGNTALT 660

Query: 661 YARQASSQECINVLLQYGCPDECV 684
           YARQASSQECINVLLQYGCPDECV
Sbjct: 661 YARQASSQECINVLLQYGCPDECV 684


>gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
           and PH domain 9 [Homo sapiens]
          Length = 684

 Score = 1377 bits (3565), Expect = 0.0
 Identities = 683/684 (99%), Positives = 683/684 (99%)

Query: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
           MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE
Sbjct: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60

Query: 61  DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD 120
           DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD
Sbjct: 61  DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD 120

Query: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180
           VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA
Sbjct: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180

Query: 181 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240
           DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP
Sbjct: 181 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240

Query: 241 TPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300
           TPVCK SMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW
Sbjct: 241 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300

Query: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360
           KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS
Sbjct: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360

Query: 361 NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420
           NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT
Sbjct: 361 NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420

Query: 421 WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480
           WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV
Sbjct: 421 WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480

Query: 481 DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA 540
           DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA
Sbjct: 481 DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA 540

Query: 541 NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL 600
           NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL
Sbjct: 541 NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL 600

Query: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLLXGVDVMARDAHGNTALT 660
           QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLL GVDVMARDAHGNTALT
Sbjct: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLLXGVDVMARDAHGNTALT 660

Query: 661 YARQASSQECINVLLQYGCPDECV 684
           YARQASSQECINVLLQYGCPDECV
Sbjct: 661 YARQASSQECINVLLQYGCPDECV 684


>gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH
           domain 5 [Homo sapiens]
          Length = 686

 Score = 1323 bits (3424), Expect = 0.0
 Identities = 660/686 (96%), Positives = 666/686 (97%), Gaps = 2/686 (0%)

Query: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
           MGNILTC VHPSVSLEFDQQQGSVCPSESEIYEAGA DRMAGAPMAAAVQPAEVTVEVGE
Sbjct: 1   MGNILTCCVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE 60

Query: 61  DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD 120
           DLHMH +RD+EMPEALEF+LSANPEASTIFQRNSQTDALEFN SANPEASTIFQRNSQTD
Sbjct: 61  DLHMHHIRDQEMPEALEFSLSANPEASTIFQRNSQTDALEFNPSANPEASTIFQRNSQTD 120

Query: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180
           VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTA QHYLTMTIISVTLEIPHHITQRDA
Sbjct: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTASQHYLTMTIISVTLEIPHHITQRDA 180

Query: 181 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240
           DRSLSIPDEQLHSFAVSTVHI K RNGGGSLNNYSSSIP TPSTSQEDPQFSVPPTANTP
Sbjct: 181 DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 240

Query: 241 TPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300
           TPVCK SMRWSNLFTSEKGS PDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW
Sbjct: 241 TPVCKRSMRWSNLFTSEKGSHPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300

Query: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360
           KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS
Sbjct: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360

Query: 361 NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420
           NGLSKDMDTGLGDSICFSP ISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT
Sbjct: 361 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420

Query: 421 WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480
           WHFEATTYEERDAWVQAIQSQILASLQSC+SSKSKSQLTSQSEAMALQSIQNMRGNAHCV
Sbjct: 421 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480

Query: 481 DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA 540
           D ETQNPKWASLNLGVLMCIECSGIHRS GTRLSRVRSLELDDWPVELRKVMSSIGN+LA
Sbjct: 481 DYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 540

Query: 541 NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL 600
           NSIWEGSSQGQTKPS+KSTREEKE WIRSKYEEKLFLAPLPCTELSLGQ LLRAT DEDL
Sbjct: 541 NSIWEGSSQGQTKPSVKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQHLLRATADEDL 600

Query: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLL--XGVDVMARDAHGNTA 658
           QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVL QLL   GVDVMARDAHGNTA
Sbjct: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 660

Query: 659 LTYARQASSQECINVLLQYGCPDECV 684
           LTYARQASSQECINVLLQYGCPDECV
Sbjct: 661 LTYARQASSQECINVLLQYGCPDECV 686


>gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens]
          Length = 686

 Score = 1316 bits (3406), Expect = 0.0
 Identities = 656/686 (95%), Positives = 663/686 (96%), Gaps = 2/686 (0%)

Query: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
           MGNILTCRVHPSVSLEFDQQQGSVCPSESE YEAGA DRMAGAPMAAAVQPAEVTVEVGE
Sbjct: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESETYEAGARDRMAGAPMAAAVQPAEVTVEVGE 60

Query: 61  DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD 120
           DLHMH VRDREMPEALEFNLSANPE+STIFQRNSQT+ALEFN SANPEASTIFQRNSQTD
Sbjct: 61  DLHMHHVRDREMPEALEFNLSANPESSTIFQRNSQTEALEFNPSANPEASTIFQRNSQTD 120

Query: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180
           VVEIRRSNCTNHVS  RFSQQYS CSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA
Sbjct: 121 VVEIRRSNCTNHVSAVRFSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180

Query: 181 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240
           DR+LSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIP TPSTSQEDPQFSVPPTANTP
Sbjct: 181 DRTLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 240

Query: 241 TPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300
           TPVCK SMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW
Sbjct: 241 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300

Query: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360
           KKKYVTLCSNG+LTYYSSLGDYMKNIHKKEIDL+TSTIKVPGKWPSLATSAC PISSSKS
Sbjct: 301 KKKYVTLCSNGMLTYYSSLGDYMKNIHKKEIDLQTSTIKVPGKWPSLATSACTPISSSKS 360

Query: 361 NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420
           NGLSKDMDTGLGDSICFSP ISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT
Sbjct: 361 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420

Query: 421 WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480
           WHFEATTYEERDAWVQAIQSQILASLQSC+SSKSKSQLTSQSEAMALQSIQNMRGNAHCV
Sbjct: 421 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480

Query: 481 DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA 540
           DCETQNPKWASLNLGVLMCIECSGIHRS G  LSRVRSLELDDWPVELRKVMSSI N+LA
Sbjct: 481 DCETQNPKWASLNLGVLMCIECSGIHRSLGPHLSRVRSLELDDWPVELRKVMSSIVNDLA 540

Query: 541 NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL 600
           NSIWEGSSQGQTKPS KSTREEKE WIRSKYEEKLFLAPLPCTELSLGQQLLRAT DEDL
Sbjct: 541 NSIWEGSSQGQTKPSEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDL 600

Query: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLL--XGVDVMARDAHGNTA 658
           QTAILLLAHGS EEVNETCGEGDGCTALHLACRKGNVVL QLL   GVDVMARDAHGNTA
Sbjct: 601 QTAILLLAHGSCEEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 660

Query: 659 LTYARQASSQECINVLLQYGCPDECV 684
           LTYARQASSQECINVLLQYGCPDECV
Sbjct: 661 LTYARQASSQECINVLLQYGCPDECV 686


>gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH
           domain 4 [Homo sapiens]
          Length = 663

 Score = 1274 bits (3296), Expect = 0.0
 Identities = 640/686 (93%), Positives = 646/686 (94%), Gaps = 25/686 (3%)

Query: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
           MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGA DRMAGAPMAAAVQPAEVTVEVGE
Sbjct: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE 60

Query: 61  DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD 120
           DLHMH VRDREMPEALEFN                        SANPEASTIFQRNSQTD
Sbjct: 61  DLHMHHVRDREMPEALEFN-----------------------PSANPEASTIFQRNSQTD 97

Query: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180
           VVEIRRSNCTNHVST RFSQQYS CSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA
Sbjct: 98  VVEIRRSNCTNHVSTVRFSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 157

Query: 181 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240
           DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIP TPSTSQEDPQFSVPPTANTP
Sbjct: 158 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 217

Query: 241 TPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300
           TPVCK SMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW
Sbjct: 218 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 277

Query: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360
           KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDL+TSTIKVPGKWPSLATSAC PIS+SKS
Sbjct: 278 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLQTSTIKVPGKWPSLATSACTPISTSKS 337

Query: 361 NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420
           NGLSKDMDTGLGDSICFSP ISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT
Sbjct: 338 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 397

Query: 421 WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480
           WHFEATTYEERDAWVQAIQSQILASLQSC+SSKSKSQLTSQS+AMALQSIQNMRGNAHCV
Sbjct: 398 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSKAMALQSIQNMRGNAHCV 457

Query: 481 DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA 540
           DCETQNPKWASLNLGVLMCIECSGIHRS GTRLSRVRSLELDDWPVELRKVMSSIGN+LA
Sbjct: 458 DCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 517

Query: 541 NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL 600
           NSIWEGSSQGQTKPS KSTREEKE WIRSKYEEKLFLAPLPCTELSLGQQLLRAT DEDL
Sbjct: 518 NSIWEGSSQGQTKPSEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDL 577

Query: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLL--XGVDVMARDAHGNTA 658
           QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVL QLL   GVDVMARDAHGNTA
Sbjct: 578 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 637

Query: 659 LTYARQASSQECINVLLQYGCPDECV 684
           LTYARQASSQECINVLLQYGCPD+CV
Sbjct: 638 LTYARQASSQECINVLLQYGCPDKCV 663


>gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH
           domain 8 [Homo sapiens]
          Length = 663

 Score = 1273 bits (3294), Expect = 0.0
 Identities = 641/686 (93%), Positives = 644/686 (93%), Gaps = 25/686 (3%)

Query: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
           MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGA DRMAGAPMAAAVQPAEVTVEVGE
Sbjct: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE 60

Query: 61  DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD 120
           DLHMH VRDREMPEALEFN                        SANPEASTIFQRNSQTD
Sbjct: 61  DLHMHHVRDREMPEALEFN-----------------------PSANPEASTIFQRNSQTD 97

Query: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180
           VVEIRRSNCTNHVST RFSQQYS CSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA
Sbjct: 98  VVEIRRSNCTNHVSTVRFSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 157

Query: 181 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240
           DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIP TPSTSQEDPQFSVPPTANTP
Sbjct: 158 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 217

Query: 241 TPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300
           TPVCK SMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW
Sbjct: 218 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 277

Query: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360
           KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDL+TSTIKVPGKWPSLATSAC PISSSKS
Sbjct: 278 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLQTSTIKVPGKWPSLATSACTPISSSKS 337

Query: 361 NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420
           NGLSKDMDTGLGDSICFSP ISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT
Sbjct: 338 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 397

Query: 421 WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480
           WHFEATTYEERDAWVQAIQSQILASLQSC+SSKSKSQLTSQSEAMALQSIQNMRGNAHCV
Sbjct: 398 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 457

Query: 481 DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA 540
           DCETQNPKWASLNLGVLMCIECSGIH S GTRLSRVRSLELDDWPVELRKVMSSIGN+LA
Sbjct: 458 DCETQNPKWASLNLGVLMCIECSGIHHSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 517

Query: 541 NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL 600
           NSIWEGSSQGQTKPS KSTREEKE WIRSKYEEKLFLAPLPCTELSLGQQLL AT DEDL
Sbjct: 518 NSIWEGSSQGQTKPSEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLWATADEDL 577

Query: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLL--XGVDVMARDAHGNTA 658
           QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVL QLL   GVDVMARDAHGNTA
Sbjct: 578 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 637

Query: 659 LTYARQASSQECINVLLQYGCPDECV 684
           LTYARQASSQECINVLLQYGCPDECV
Sbjct: 638 LTYARQASSQECINVLLQYGCPDECV 663


>gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH
           domain 7 [Homo sapiens]
          Length = 663

 Score = 1262 bits (3266), Expect = 0.0
 Identities = 635/686 (92%), Positives = 641/686 (93%), Gaps = 25/686 (3%)

Query: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
           MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE
Sbjct: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60

Query: 61  DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD 120
           DLHMH VRDREMPEALEFN                        SANPEASTIFQRNSQTD
Sbjct: 61  DLHMHHVRDREMPEALEFN-----------------------PSANPEASTIFQRNSQTD 97

Query: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180
           VVEIRRSNCTNHVST  FSQQYS CSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA
Sbjct: 98  VVEIRRSNCTNHVSTVHFSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 157

Query: 181 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240
           DRSLSIPDEQLHSFAVSTVHI K RNGGGSLNNYSSSIP TPSTSQEDPQFSVPPTANTP
Sbjct: 158 DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 217

Query: 241 TPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300
           TPVCK SMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW
Sbjct: 218 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 277

Query: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360
           KKKYVTLCSNGVLTYYSSLGDYMK IHKKEIDL+TSTIKVPGKWPSLAT AC PISSSKS
Sbjct: 278 KKKYVTLCSNGVLTYYSSLGDYMKYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKS 337

Query: 361 NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420
           +GLSKDMDTGLGDSICFSP ISSTT PKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT
Sbjct: 338 DGLSKDMDTGLGDSICFSPSISSTTIPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 397

Query: 421 WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480
           WHFEATTYEERDAWVQAIQSQILASLQSC+SSKSKSQLTSQSEAMALQSIQNMRGNAHCV
Sbjct: 398 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 457

Query: 481 DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA 540
           DCETQNPKWASLNLGVLMCIECSGIHRS GTRLSRVRSLELDDWPVELRKVMSSIGN+LA
Sbjct: 458 DCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 517

Query: 541 NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL 600
           NSIWEGSSQG+TKP+ KSTREEKE WIRSKYEEKLFLAPLPCTELSLGQQLLRAT DEDL
Sbjct: 518 NSIWEGSSQGRTKPTEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDL 577

Query: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLL--XGVDVMARDAHGNTA 658
           QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVL QLL   GVDVMARDAHGNTA
Sbjct: 578 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 637

Query: 659 LTYARQASSQECINVLLQYGCPDECV 684
           LTYARQASSQECINVLLQYGCPDECV
Sbjct: 638 LTYARQASSQECINVLLQYGCPDECV 663


>gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activating
           protein 11 [Homo sapiens]
          Length = 550

 Score =  959 bits (2480), Expect = 0.0
 Identities = 489/550 (88%), Positives = 500/550 (90%), Gaps = 27/550 (4%)

Query: 162 MTIISVTLEIPHHITQRDADRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPT 221
           MTIISVTLEI HHIT+RDADRSL+I DEQL+SFA STVHI KKRNGGGSLNNYSSSIP T
Sbjct: 1   MTIISVTLEIHHHITERDADRSLTILDEQLYSFAFSTVHITKKRNGGGSLNNYSSSIPLT 60

Query: 222 PSTSQEDPQFSVPPTANTPTPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRA 281
           PSTSQED  FSVPPTANTPTP+CK SM WSNLFTSEKGSDPDK RKA E+HADTIGSGRA
Sbjct: 61  PSTSQEDLYFSVPPTANTPTPICKQSMGWSNLFTSEKGSDPDKGRKALESHADTIGSGRA 120

Query: 282 IPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVP 341
           IPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVP
Sbjct: 121 IPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVP 180

Query: 342 GKWPSLATSACAPISSSKSNGLSKDM---------DTGLGDSICFSPGISSTTSPKLNPP 392
           GKWPSLATSACAPISSSKSNGLSKDM         D GLGDSICFSP ISSTTSPKLN P
Sbjct: 181 GKWPSLATSACAPISSSKSNGLSKDMEALHMSANSDIGLGDSICFSPSISSTTSPKLNLP 240

Query: 393 PSPHANKKKHLKKKSTNN----------------FMIVSATGQTWHFEATTYEERDAWVQ 436
           PSPHANKKKHLKKKSTNN                FMIVS TGQT HF+ATTYEERDAWVQ
Sbjct: 241 PSPHANKKKHLKKKSTNNLKDDGLSSTAEEEEEKFMIVSVTGQTCHFKATTYEERDAWVQ 300

Query: 437 AIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGV 496
           AIQSQILASLQSC+SSKSKSQLTSQSEAMALQSIQNMRGN+HCVDCETQNPKWASLNLGV
Sbjct: 301 AIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNSHCVDCETQNPKWASLNLGV 360

Query: 497 LMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELANSIWEGSSQGQTKPSI 556
           LMCIECSGIHRS GTRLSRVRSLELDDWPVELRKVMSSIGN+LANSIWEGSSQGQTKPSI
Sbjct: 361 LMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSI 420

Query: 557 KSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDLQTAILLLAHGSREEVN 616
           +STREEKE WIRSKYE KLFLAPLPCTELSLGQ LLRAT DEDL+TAILLLAHGSREEVN
Sbjct: 421 ESTREEKERWIRSKYEHKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSREEVN 480

Query: 617 ETCGEGDGCTALHLACRKGNVVLEQLL--XGVDVMARDAHGNTALTYARQASSQECINVL 674
           ETCGEGDGCTALHLACRKGNVVL QLL   GVDVMARDAHGNTALTYARQASSQECINVL
Sbjct: 481 ETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVL 540

Query: 675 LQYGCPDECV 684
           LQYGCPDECV
Sbjct: 541 LQYGCPDECV 550


>gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens]
          Length = 804

 Score =  791 bits (2042), Expect = 0.0
 Identities = 406/532 (76%), Positives = 446/532 (83%), Gaps = 34/532 (6%)

Query: 185 SIPDEQLHSFA----VSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240
           S+P+   HS      VS VHI +  NGGGSL++YSSS+P TPSTSQ++ +  VPPTANTP
Sbjct: 245 SLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTP 304

Query: 241 TPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KT 299
           TPV K S R SNLFTS KGSDPDKE+K  E+ AD+IGSGRAIPIKQGMLLKRSGK L K 
Sbjct: 305 TPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKE 364

Query: 300 WKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSK 359
           WKKKYVTLC NGVLTY+ SL DYM+N+H KEIDL  +T+KVPGK P  ATSACAPISS K
Sbjct: 365 WKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPK 424

Query: 360 SNGLSKDM---------DTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNN 410
           +NGLSKDM         DTGLGDS+C SP ISSTTSPKL+PPPSPHAN+KKH +KKST+N
Sbjct: 425 TNGLSKDMSSLHISPNSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSN 484

Query: 411 F------------------MIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCKSS 452
           F                  +IVS TGQTWHFEATTYEERDAWVQAI+SQILASLQSC+SS
Sbjct: 485 FKADGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESS 544

Query: 453 KSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTR 512
           K+KS+LTSQSEAMALQSI+NMRGN+HCVDCETQNP WASLNLG LMCIECSGIHR+ GT 
Sbjct: 545 KNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTH 604

Query: 513 LSRVRSLELDDWPVELRKVMSSIGNELANSIWEGSSQGQTKPSIKSTREEKEWWIRSKYE 572
           LSRVRSL+LDDWPVEL KVMSSIGNELANS+WE SSQG+TKPS+ STREEKE WIR+KYE
Sbjct: 605 LSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYE 664

Query: 573 EKLFLAPLPCTELSLGQQLLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLAC 632
           +KLFLAPLPCTELSLGQ LLRAT DEDL+TAILLLAHGSR+EVNETCGEGDG TALHLAC
Sbjct: 665 QKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLAC 724

Query: 633 RKGNVVLEQLL--XGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDE 682
           RKGNVVL QLL   GVDV ARDAHGNTAL YARQASSQECI+VLLQYGCPDE
Sbjct: 725 RKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDE 776


>gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens]
          Length = 911

 Score =  551 bits (1419), Expect = e-156
 Identities = 299/582 (51%), Positives = 383/582 (65%), Gaps = 84/582 (14%)

Query: 185 SIPDEQLHSF----AVSTVHIMKKRNGGGS-LNNYSSSIPPTPSTSQEDPQFSVPPTANT 239
           S+P+   HS     ++  VHI +  NGGGS  ++YSSS+P TPS SQ + +      ++T
Sbjct: 301 SLPNSPSHSAVSAASIPAVHINQATNGGGSAFSDYSSSVPSTPSISQRELRIETIAASST 360

Query: 240 PTPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-K 298
           PTP+ K S R SN+FTS KG+D D+E+KA E   D+IGSGRAIPIKQG+LLKRSGK L K
Sbjct: 361 PTPIRKQSKRRSNIFTSRKGADLDREKKAAECKVDSIGSGRAIPIKQGILLKRSGKSLNK 420

Query: 299 TWKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACA----- 353
            WKKKYVTLC NG+LTY+ SL DYM+NIH KEIDL  +T+KVPGK    AT A A     
Sbjct: 421 EWKKKYVTLCDNGLLTYHPSLHDYMQNIHGKEIDLLRTTVKVPGKRLPRATPATAPGTSP 480

Query: 354 ---------------------------------PISSS-----KSNGLSK------DMDT 369
                                            P+SSS     +  GL +        D 
Sbjct: 481 RANGLSVERSNTQLGGGTGAPHSASSASLHSERPLSSSAWAGPRPEGLHQRSCSVSSADQ 540

Query: 370 GLGDSICFSPGISS---------TTSPKLNPPPSPHANKKKHLKKKSTNN---------- 410
               +    PG+           ++SPKL+PPPSPH+N+KKH +KKST            
Sbjct: 541 WSEATTSLPPGMQHPASGPAEVLSSSPKLDPPPSPHSNRKKHRRKKSTGTPRPDGPSSAT 600

Query: 411 --------FMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQS 462
                   F++VS TGQTWHFEA+T EER+ WVQ++Q+QILASLQ C+S+K K++L +Q+
Sbjct: 601 EEAEESFEFVVVSLTGQTWHFEASTAEERELWVQSVQAQILASLQGCRSAKDKTRLGNQN 660

Query: 463 EAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELD 522
            A+A+Q+++ +RGN+ C+DC+  NP WASLNLG LMCIECSGIHR  G  LSRVRSL+LD
Sbjct: 661 AALAVQAVRTVRGNSFCIDCDAPNPDWASLNLGALMCIECSGIHRHLGAHLSRVRSLDLD 720

Query: 523 DWPVELRKVMSSIGNELANSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPC 582
           DWP EL  VM+++GN LANS+WEG+  G +KP   + REEKE WIR+KYE+KLFLAPLP 
Sbjct: 721 DWPPELLAVMTAMGNALANSVWEGALGGYSKPGPDACREEKERWIRAKYEQKLFLAPLPS 780

Query: 583 TELSLGQQLLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQL 642
           +++ LGQQLLRA  ++DL+  ++LLAHGS+EEVNET G+GDG TALHL+    NVV  QL
Sbjct: 781 SDVPLGQQLLRAVVEDDLRLLVMLLAHGSKEEVNETYGDGDGRTALHLSSAMANVVFTQL 840

Query: 643 L--XGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDE 682
           L   GVDV +RDA G T L YAR+A SQEC ++L+Q+GCP E
Sbjct: 841 LIWYGVDVRSRDARGLTPLAYARRAGSQECADILIQHGCPGE 882


>gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens]
          Length = 857

 Score =  550 bits (1418), Expect = e-156
 Identities = 280/369 (75%), Positives = 307/369 (83%), Gaps = 30/369 (8%)

Query: 334 RTSTIKVPGKWPSLATSACAPISSSKSNGLSKDMDTGLGDSICFSPGISSTTSPKLNPPP 393
           R+ ++    +W      A + ISS          DTGLGDS+C SP ISSTTSPKL+PPP
Sbjct: 471 RSYSVSSADQWSEATVIANSAISS----------DTGLGDSVCSSPSISSTTSPKLDPPP 520

Query: 394 SPHANKKKHLKKKSTNNF------------------MIVSATGQTWHFEATTYEERDAWV 435
           SPHAN+KKH +KKST+NF                  +IVS TGQTWHFEATTYEERDAWV
Sbjct: 521 SPHANRKKHRRKKSTSNFKADGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWV 580

Query: 436 QAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLG 495
           QAI+SQILASLQSC+SSK+KS+LTSQSEAMALQSI+NMRGN+HCVDCETQNP WASLNLG
Sbjct: 581 QAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLG 640

Query: 496 VLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELANSIWEGSSQGQTKPS 555
            LMCIECSGIHR+ GT LSRVRSL+LDDWPVEL KVMSSIGNELANS+WE SSQG+TKPS
Sbjct: 641 ALMCIECSGIHRNLGTHLSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPS 700

Query: 556 IKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDLQTAILLLAHGSREEV 615
           + STREEKE WIR+KYE+KLFLAPLPCTELSLGQ LLRAT DEDL+TAILLLAHGSR+EV
Sbjct: 701 VDSTREEKERWIRAKYEQKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEV 760

Query: 616 NETCGEGDGCTALHLACRKGNVVLEQLL--XGVDVMARDAHGNTALTYARQASSQECINV 673
           NETCGEGDG TALHLACRKGNVVL QLL   GVDV ARDAHGNTAL YARQASSQECI+V
Sbjct: 761 NETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDV 820

Query: 674 LLQYGCPDE 682
           LLQYGCPDE
Sbjct: 821 LLQYGCPDE 829



 Score =  256 bits (654), Expect = 5e-68
 Identities = 137/207 (66%), Positives = 157/207 (75%), Gaps = 10/207 (4%)

Query: 185 SIPDEQLHSFA----VSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240
           S+P+   HS      VS VHI +  NGGGSL++YSSS+P TPSTSQ++ +  VPPTANTP
Sbjct: 245 SLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTP 304

Query: 241 TPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KT 299
           TPV K S R SNLFTS KGSDPDKE+K  E+ AD+IGSGRAIPIKQGMLLKRSGK L K 
Sbjct: 305 TPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKE 364

Query: 300 WKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSK 359
           WKKKYVTLC NGVLTY+ SL DYM+N+H KEIDL  +T+KVPGK P  ATSACAPISS K
Sbjct: 365 WKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPK 424

Query: 360 SNGLSKDMDTGLGDSICFSPGISSTTS 386
           +NGLSKDM      S+  SP   + TS
Sbjct: 425 TNGLSKDM-----SSLHISPNSGNVTS 446


>gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens]
          Length = 836

 Score =  449 bits (1155), Expect = e-126
 Identities = 259/557 (46%), Positives = 341/557 (61%), Gaps = 65/557 (11%)

Query: 185 SIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTPTP-- 242
           S+P    HS A + V    + + GG  ++YSSS+P +P+    + +      A   TP  
Sbjct: 245 SLPSSPSHSAASTPV--AGQASNGGHTSDYSSSLPSSPNVGHRELRAEAAAVAGLSTPGS 302

Query: 243 VCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KTWK 301
           + + + R ++LF + +GSD   E+++ ++  +T GSGRAIPIKQ  LLKRSG  L K WK
Sbjct: 303 LHRAAKRRTSLFANRRGSD--SEKRSLDSRGETTGSGRAIPIKQSFLLKRSGNSLNKEWK 360

Query: 302 KKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKSN 361
           KKYVTL SNG L Y+ S+ DY+ + H KE+DL  +T+KVPGK P  A SA  P  S+  N
Sbjct: 361 KKYVTLSSNGFLLYHPSINDYIHSTHGKEMDLLRTTVKVPGKRPPRAISAFGP--SASIN 418

Query: 362 GLSKDMDT-GLGDSI-------CFSPGISSTTSP-------------------------- 387
           GL KDM T  +G+ +         SP  SS   P                          
Sbjct: 419 GLVKDMSTVQMGEGLEATTPMPSPSPSPSSLQPPPDQTSKHLLKPDRNLARALSTDCTPS 478

Query: 388 ------KLNPPPSPHANKKKHLK--------------KKSTNNFMIVSATGQTWHFEATT 427
                    PPPSP   K++  K              ++    F+IVS+TGQTWHFEA +
Sbjct: 479 GDLSPLSREPPPSPMVKKQRRKKLTTPSKTEGSAGQAEEENFEFLIVSSTGQTWHFEAAS 538

Query: 428 YEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNP 487
           +EERDAWVQAI+SQILASLQ C+SSK K +  SQSEA+A+Q+I+N +GN+ CVDC   NP
Sbjct: 539 FEERDAWVQAIESQILASLQCCESSKVKLRTDSQSEAVAIQAIRNAKGNSICVDCGAPNP 598

Query: 488 KWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELANSIWEGS 547
            WASLNLG L+CIECSGIHR+ GT LSRVRSL+LDDWP EL  V+++IGN+ AN +WE  
Sbjct: 599 TWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDWPRELTLVLTAIGNDTANRVWESD 658

Query: 548 SQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDLQTAILLL 607
           ++G+ KPS  S+REE+E WIR+KYE+ LFLAPL  +E  LG+QL  A   +D+ T +LLL
Sbjct: 659 TRGRAKPSRDSSREERESWIRAKYEQLLFLAPLSTSEEPLGRQLWAAVQAQDVATVLLLL 718

Query: 608 AHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLL--XGVDVMARDAHGNTALTYARQA 665
           AH     ++ +  +    + LHLA    +VV+ QLL   G DV ARDA G TAL YARQA
Sbjct: 719 AHARHGPLDTSVEDPQLRSPLHLAAELAHVVITQLLLWYGADVAARDAQGRTALFYARQA 778

Query: 666 SSQECINVLLQYGCPDE 682
            SQ C ++LLQ+GCP E
Sbjct: 779 GSQLCADILLQHGCPGE 795


>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
          Length = 1192

 Score =  441 bits (1134), Expect = e-123
 Identities = 259/577 (44%), Positives = 341/577 (59%), Gaps = 85/577 (14%)

Query: 185  SIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTPTP-- 242
            S+P    HS A + V    + + GG  ++YSSS+P +P+    + +      A   TP  
Sbjct: 581  SLPSSPSHSAASTPV--AGQASNGGHTSDYSSSLPSSPNVGHRELRAEAAAVAGLSTPGS 638

Query: 243  VCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KTWK 301
            + + + R ++LF + +GSD   E+++ ++  +T GSGRAIPIKQ  LLKRSG  L K WK
Sbjct: 639  LHRAAKRRTSLFANRRGSD--SEKRSLDSRGETTGSGRAIPIKQSFLLKRSGNSLNKEWK 696

Query: 302  KKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKSN 361
            KKYVTL SNG L Y+ S+ DY+ + H KE+DL  +T+KVPGK P  A SA  P  S+  N
Sbjct: 697  KKYVTLSSNGFLLYHPSINDYIHSTHGKEMDLLRTTVKVPGKRPPRAISAFGP--SASIN 754

Query: 362  GLSKDMDT-GLGDSI-------CFSPGISSTTSP-------------------------- 387
            GL KDM T  +G+ +         SP  SS   P                          
Sbjct: 755  GLVKDMSTVQMGEGLEATTPMPSPSPSPSSLQPPPDQTSKHLLKPDRNLARALSTDCTPS 814

Query: 388  ------KLNPPPSPHANKKKHLKKKSTNN------------------------------- 410
                     PPPSP   K++  K  + +                                
Sbjct: 815  GDLSPLSREPPPSPMVKKQRRKKLTTPSKTEGSAGQAEAKRKMWKLKSFGSLRNIYKAEE 874

Query: 411  ---FMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMAL 467
               F+IVS+TGQTWHFEA ++EERDAWVQAI+SQILASLQ C+SSK K +  SQSEA+A+
Sbjct: 875  NFEFLIVSSTGQTWHFEAASFEERDAWVQAIESQILASLQCCESSKVKLRTDSQSEAVAI 934

Query: 468  QSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVE 527
            Q+I+N +GN+ CVDC   NP WASLNLG L+CIECSGIHR+ GT LSRVRSL+LDDWP E
Sbjct: 935  QAIRNAKGNSICVDCGAPNPTWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDWPRE 994

Query: 528  LRKVMSSIGNELANSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSL 587
            L  V+++IGN+ AN +WE  ++G+ KPS  S+REE+E WIR+KYE+ LFLAPL  +E  L
Sbjct: 995  LTLVLTAIGNDTANRVWESDTRGRAKPSRDSSREERESWIRAKYEQLLFLAPLSTSEEPL 1054

Query: 588  GQQLLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLL--XG 645
            G+QL  A   +D+ T +LLLAH     ++ +  +    + LHLA    +VV+ QLL   G
Sbjct: 1055 GRQLWAAVQAQDVATVLLLLAHARHGPLDTSVEDPQLRSPLHLAAELAHVVITQLLLWYG 1114

Query: 646  VDVMARDAHGNTALTYARQASSQECINVLLQYGCPDE 682
             DV ARDA G TAL YARQA SQ C ++LLQ+GCP E
Sbjct: 1115 ADVAARDAQGRTALFYARQAGSQLCADILLQHGCPGE 1151


>gi|239755300 PREDICTED: similar to centaurin, gamma-like family,
           member 1 [Homo sapiens]
          Length = 284

 Score =  327 bits (837), Expect = 3e-89
 Identities = 164/173 (94%), Positives = 166/173 (95%), Gaps = 2/173 (1%)

Query: 514 SRVRSLELDDWPVELRKVMSSIGNELANSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEE 573
           SRVRSLELDDWPVELRKVMSSIGN+LANSIWEGSSQGQTKPS KSTREEKE WIRSKYEE
Sbjct: 112 SRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSEKSTREEKERWIRSKYEE 171

Query: 574 KLFLAPLPCTELSLGQQLLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACR 633
           KLFLAPLPCT+LSLGQQLLRAT DEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACR
Sbjct: 172 KLFLAPLPCTDLSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACR 231

Query: 634 KGNVVLEQLL--XGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDECV 684
           KGNVVL QLL   GVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDECV
Sbjct: 232 KGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDECV 284



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 18/18 (100%), Positives = 18/18 (100%)

Query: 178 RDADRSLSIPDEQLHSFA 195
           RDADRSLSIPDEQLHSFA
Sbjct: 94  RDADRSLSIPDEQLHSFA 111


>gi|239755288 PREDICTED: cyclin Y-like 2 [Homo sapiens]
          Length = 362

 Score =  159 bits (403), Expect = 6e-39
 Identities = 102/200 (51%), Positives = 117/200 (58%), Gaps = 28/200 (14%)

Query: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
           MGNILTC V P  S    Q QG VC  ESEIYEA A D +AG P+AAAV+P EVT   GE
Sbjct: 1   MGNILTCCVCPRASPGLHQHQGLVCHCESEIYEAAAGDLIAGVPVAAAVEPGEVTFVAGE 60

Query: 61  DLHMHQVRDREMPE--ALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQ 118
            LHMH + +REMPE   LE N S +P+ASTIF R SQTD                     
Sbjct: 61  GLHMHHICEREMPEDIPLEPNPSDHPKASTIFLRKSQTD--------------------- 99

Query: 119 TDVVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISV--TLEIPHHIT 176
              V+ ++      VSTE F+QQYSSCSTIFLDDS A Q +LTMT+ S      I  +  
Sbjct: 100 ---VQEKKKKQLCKVSTEHFTQQYSSCSTIFLDDSIASQPHLTMTLKSXCDLGTILSYQA 156

Query: 177 QRDADRSLSIPDEQLHSFAV 196
           +RDA RSL I DEQLH   V
Sbjct: 157 KRDAHRSLGIFDEQLHPLTV 176


>gi|239749780 PREDICTED: cyclin Y-like 2 [Homo sapiens]
          Length = 362

 Score =  159 bits (403), Expect = 6e-39
 Identities = 102/200 (51%), Positives = 117/200 (58%), Gaps = 28/200 (14%)

Query: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
           MGNILTC V P  S    Q QG VC  ESEIYEA A D +AG P+AAAV+P EVT   GE
Sbjct: 1   MGNILTCCVCPRASPGLHQHQGLVCHCESEIYEAAAGDLIAGVPVAAAVEPGEVTFVAGE 60

Query: 61  DLHMHQVRDREMPE--ALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQ 118
            LHMH + +REMPE   LE N S +P+ASTIF R SQTD                     
Sbjct: 61  GLHMHHICEREMPEDIPLEPNPSDHPKASTIFLRKSQTD--------------------- 99

Query: 119 TDVVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISV--TLEIPHHIT 176
              V+ ++      VSTE F+QQYSSCSTIFLDDS A Q +LTMT+ S      I  +  
Sbjct: 100 ---VQEKKKKQLCKVSTEHFTQQYSSCSTIFLDDSIASQPHLTMTLKSXCDLGTILSYQA 156

Query: 177 QRDADRSLSIPDEQLHSFAV 196
           +RDA RSL I DEQLH   V
Sbjct: 157 KRDAHRSLGIFDEQLHPLTV 176


>gi|239744040 PREDICTED: cyclin Y-like 2 [Homo sapiens]
          Length = 362

 Score =  159 bits (403), Expect = 6e-39
 Identities = 102/200 (51%), Positives = 117/200 (58%), Gaps = 28/200 (14%)

Query: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
           MGNILTC V P  S    Q QG VC  ESEIYEA A D +AG P+AAAV+P EVT   GE
Sbjct: 1   MGNILTCCVCPRASPGLHQHQGLVCHCESEIYEAAAGDLIAGVPVAAAVEPGEVTFVAGE 60

Query: 61  DLHMHQVRDREMPE--ALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQ 118
            LHMH + +REMPE   LE N S +P+ASTIF R SQTD                     
Sbjct: 61  GLHMHHICEREMPEDIPLEPNPSDHPKASTIFLRKSQTD--------------------- 99

Query: 119 TDVVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISV--TLEIPHHIT 176
              V+ ++      VSTE F+QQYSSCSTIFLDDS A Q +LTMT+ S      I  +  
Sbjct: 100 ---VQEKKKKQLCKVSTEHFTQQYSSCSTIFLDDSIASQPHLTMTLKSXCDLGTILSYQA 156

Query: 177 QRDADRSLSIPDEQLHSFAV 196
           +RDA RSL I DEQLH   V
Sbjct: 157 KRDAHRSLGIFDEQLHPLTV 176


>gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH domains
           3 [Homo sapiens]
          Length = 834

 Score =  142 bits (359), Expect = 8e-34
 Identities = 80/192 (41%), Positives = 113/192 (58%), Gaps = 22/192 (11%)

Query: 411 FMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQ----SCKS-------SKSKSQLT 459
           F ++S T ++   +A + + R AWVQA+Q+ I ++ +    SC S       S S S + 
Sbjct: 332 FEVLSPT-KSCMLQADSEKLRQAWVQAVQASIASAYRESPDSCYSERLDRTASPSTSSID 390

Query: 460 SQSEAM--------ALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGT 511
           S ++           LQ +Q++ GN+ C DC   +P+WAS+NLGVL+CIECSGIHRS G 
Sbjct: 391 SATDTRERGVKGESVLQRVQSVAGNSQCGDCGQPDPRWASINLGVLLCIECSGIHRSLGV 450

Query: 512 RLSRVRSLELDDWPVELRKVMSSIGNELANSIWEGSSQ--GQTKPSIKSTREEKEWWIRS 569
             S+VRSL LD W  EL K+M  +GN   N I+E   +  G  KP+  S+R++KE WI+ 
Sbjct: 451 HCSKVRSLTLDSWEPELLKLMCELGNSAVNQIYEAQCEGAGSRKPTASSSRQDKEAWIKD 510

Query: 570 KYEEKLFLAPLP 581
           KY EK FL   P
Sbjct: 511 KYVEKKFLRKAP 522


>gi|187608516 centaurin, beta 2 [Homo sapiens]
          Length = 778

 Score =  129 bits (325), Expect = 7e-30
 Identities = 75/186 (40%), Positives = 109/186 (58%), Gaps = 21/186 (11%)

Query: 411 FMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSC---------KSSKSKSQLTSQ 461
           F +VS T ++   +A + + R AW++A+Q+ I  + +           KSS S   L S 
Sbjct: 330 FEVVSPT-KSCMLQADSEKLRQAWIKAVQTSIATAYREKGDESEKLDKKSSPSTGSLDSG 388

Query: 462 SEAM--------ALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRL 513
           +E+         ALQ +Q + GNA C DC   +P+WAS+NLG+ +CIECSGIHRS G   
Sbjct: 389 NESKEKLLKGESALQRVQCIPGNASCCDCGLADPRWASINLGITLCIECSGIHRSLGVHF 448

Query: 514 SRVRSLELDDWPVELRKVMSSIGNELANSIWEGS--SQGQTKPSIKSTREEKEWWIRSKY 571
           S+VRSL LD W  EL K+M  +GN++ N ++E +    G  KP     R+EKE +IR+KY
Sbjct: 449 SKVRSLTLDTWEPELLKLMCELGNDVINRVYEANVEKMGIKKPQ-PGQRQEKEAYIRAKY 507

Query: 572 EEKLFL 577
            E+ F+
Sbjct: 508 VERKFV 513


>gi|7661880 centaurin beta1 [Homo sapiens]
          Length = 740

 Score =  126 bits (317), Expect = 6e-29
 Identities = 73/194 (37%), Positives = 99/194 (51%), Gaps = 26/194 (13%)

Query: 414 VSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCKSSKSK-------------SQLTS 460
           V +T ++   +A +      WV A+QS I ++    +   S              S  T 
Sbjct: 331 VVSTSKSCLLQADSERLLQLWVSAVQSSIASAFSQARLDDSPRGPGQGSGHLAIGSAATL 390

Query: 461 QSEAMA-----------LQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSF 509
            S  MA           +  +Q++ GNA C DC    P+WAS+NLGV +CI+CSGIHRS 
Sbjct: 391 GSGGMARGREPGGVGHVVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSL 450

Query: 510 GTRLSRVRSLELDDWPVELRKVMSSIGNELANSIWEGSSQGQT--KPSIKSTREEKEWWI 567
           G   S+VRSL LD W  EL K+M  +GN + N I+E   +     KP    +R+EKE WI
Sbjct: 451 GVHFSKVRSLTLDSWEPELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWI 510

Query: 568 RSKYEEKLFLAPLP 581
            +KY EK FL  LP
Sbjct: 511 HAKYVEKKFLTKLP 524



 Score = 33.5 bits (75), Expect = 0.67
 Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 6/86 (6%)

Query: 591 LLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLLX--GVDV 648
           L++AT    L     LL +G+     ++ G G     LH A   G+  L  L    G D+
Sbjct: 611 LIQATAANSLLACEFLLQNGANVNQADSAGRGP----LHHATILGHTGLACLFLKRGADL 666

Query: 649 MARDAHGNTALTYARQASSQECINVL 674
            ARD+ G   LT A + ++ + + +L
Sbjct: 667 GARDSEGRDPLTIAMETANADIVTLL 692


>gi|46094081 development and differentiation enhancing factor 1
           [Homo sapiens]
          Length = 1129

 Score =  122 bits (307), Expect = 8e-28
 Identities = 92/296 (31%), Positives = 141/296 (47%), Gaps = 28/296 (9%)

Query: 395 PHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAI---QSQILASLQSCKS 451
           P+A  KK     S N         +T+HF+A   ++  AW+  +   + + L      + 
Sbjct: 377 PNAEDKKSFDLISHN---------RTYHFQAEDEQDYVAWISVLTNSKEEALTMAFRGEQ 427

Query: 452 SKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGT 511
           S  ++ L   ++A+ ++ +Q + GN  C DC +  P W S NLG+L CIECSGIHR  G 
Sbjct: 428 SAGENSLEDLTKAI-IEDVQRLPGNDICCDCGSSEPTWLSTNLGILTCIECSGIHREMGV 486

Query: 512 RLSRVRSLELDDWPVELRKVMSSIGNELANSIWEGSSQGQT-KPSIKSTREEKEWWIRSK 570
            +SR++SLELD        +  ++GN   N I E +    + KP+  S    ++ +I +K
Sbjct: 487 HISRIQSLELDKLGTSELLLAKNVGNNSFNDIMEANLPSPSPKPTPSSDMTVRKEYITAK 546

Query: 571 YEEKLFLAPLPCTELSLGQQLLRATTDEDLQTAILLLAHGSR--EEVNETCGEGDGCTAL 628
           Y +  F      T  +   +LL A    DL   I + A G    E + E  G+  G TAL
Sbjct: 547 YVDHRFSRKTCSTSSAKLNELLEAIKSRDLLALIQVYAEGVELMEPLLEP-GQELGETAL 605

Query: 629 HLACRKGNVVLEQLLXGVDVMARD--------AHGNTALTYARQASSQECINVLLQ 676
           HLA R  +   +  L  VD + ++        A GNT L Y    S  EC+ +LL+
Sbjct: 606 HLAVRTAD---QTSLHLVDFLVQNCGNLDKQTALGNTVLHYCSMYSKPECLKLLLR 658


>gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
           isoform b [Homo sapiens]
          Length = 894

 Score =  111 bits (277), Expect = 3e-24
 Identities = 87/279 (31%), Positives = 132/279 (47%), Gaps = 26/279 (9%)

Query: 419 QTWHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEA-----------MAL 467
           +T+HF+A    E +AWV  +Q+    +L S    +  +   S   A           + +
Sbjct: 361 RTYHFQAEDEHECEAWVSVLQNSKDEALSSAFLGEPSAGPGSWGSAGHDGEPHDLTKLLI 420

Query: 468 QSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELD-DWPV 526
             +++  GN+ C DC   +P W S NLGVL CI+CSG+HR  G R SR++SL LD   P 
Sbjct: 421 AEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPS 480

Query: 527 ELRKVMSSIGNELANSIWEGS--SQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTE 584
           EL   + ++GN   N + E    S G  KPS +S    +  +I +KY E  F     CT 
Sbjct: 481 ELLLAL-NMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHRFAR--RCTP 537

Query: 585 LSLGQQLLRATTDEDLQTAILLLAHGS--REEVNETCGEGDGCTALHLACRKGNVVLEQL 642
               Q+L  A  + DL + +   A+G    + +     +      LHLA +  N     L
Sbjct: 538 EP--QRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPL 595

Query: 643 L-----XGVDVMARDAHGNTALTYARQASSQECINVLLQ 676
           +      G  + A+ A GNTAL YA   +  +C+ +LL+
Sbjct: 596 VDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLK 634


>gi|19923540 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
           isoform a [Homo sapiens]
          Length = 903

 Score =  111 bits (277), Expect = 3e-24
 Identities = 87/279 (31%), Positives = 132/279 (47%), Gaps = 26/279 (9%)

Query: 419 QTWHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEA-----------MAL 467
           +T+HF+A    E +AWV  +Q+    +L S    +  +   S   A           + +
Sbjct: 370 RTYHFQAEDEHECEAWVSVLQNSKDEALSSAFLGEPSAGPGSWGSAGHDGEPHDLTKLLI 429

Query: 468 QSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELD-DWPV 526
             +++  GN+ C DC   +P W S NLGVL CI+CSG+HR  G R SR++SL LD   P 
Sbjct: 430 AEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPS 489

Query: 527 ELRKVMSSIGNELANSIWEGS--SQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTE 584
           EL   + ++GN   N + E    S G  KPS +S    +  +I +KY E  F     CT 
Sbjct: 490 ELLLAL-NMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHRFAR--RCTP 546

Query: 585 LSLGQQLLRATTDEDLQTAILLLAHGS--REEVNETCGEGDGCTALHLACRKGNVVLEQL 642
               Q+L  A  + DL + +   A+G    + +     +      LHLA +  N     L
Sbjct: 547 EP--QRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPL 604

Query: 643 L-----XGVDVMARDAHGNTALTYARQASSQECINVLLQ 676
           +      G  + A+ A GNTAL YA   +  +C+ +LL+
Sbjct: 605 VDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLK 643


>gi|206725422 G protein-coupled receptor kinase interacting ArfGAP 2
           isoform 5 [Homo sapiens]
          Length = 729

 Score =  111 bits (277), Expect = 3e-24
 Identities = 71/222 (31%), Positives = 111/222 (50%), Gaps = 19/222 (8%)

Query: 471 QNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRK 530
           + +R +  C DC   +P WAS+N G  +C EC  +HRS G  +S+VR L+   WP  L +
Sbjct: 3   KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62

Query: 531 VMSSIGNELANSIWEGS-------SQGQTKPSIK-STREEKEWWIRSKYEEKLFLAPLPC 582
           ++ ++ N  ANSIWE S         G+ K + +      K  +IR+KY+   F+  LPC
Sbjct: 63  MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122

Query: 583 ------TELSLGQQLLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 636
                 T   L +QL  +    +L+T + LL+ G++           G T LH+A + G 
Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179

Query: 637 VVLEQLL--XGVDVMARDAHGNTALTYARQASSQECINVLLQ 676
           ++  +LL   G D   +D+ G T + YARQ    E    L++
Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221


>gi|206725420 G protein-coupled receptor kinase interacting ArfGAP 2
           isoform 6 [Homo sapiens]
          Length = 681

 Score =  111 bits (277), Expect = 3e-24
 Identities = 71/222 (31%), Positives = 111/222 (50%), Gaps = 19/222 (8%)

Query: 471 QNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRK 530
           + +R +  C DC   +P WAS+N G  +C EC  +HRS G  +S+VR L+   WP  L +
Sbjct: 3   KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62

Query: 531 VMSSIGNELANSIWEGS-------SQGQTKPSIK-STREEKEWWIRSKYEEKLFLAPLPC 582
           ++ ++ N  ANSIWE S         G+ K + +      K  +IR+KY+   F+  LPC
Sbjct: 63  MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122

Query: 583 ------TELSLGQQLLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 636
                 T   L +QL  +    +L+T + LL+ G++           G T LH+A + G 
Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179

Query: 637 VVLEQLL--XGVDVMARDAHGNTALTYARQASSQECINVLLQ 676
           ++  +LL   G D   +D+ G T + YARQ    E    L++
Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221


>gi|21237786 G protein-coupled receptor kinase interacting ArfGAP 2
           isoform 3 [Homo sapiens]
          Length = 679

 Score =  111 bits (277), Expect = 3e-24
 Identities = 71/222 (31%), Positives = 111/222 (50%), Gaps = 19/222 (8%)

Query: 471 QNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRK 530
           + +R +  C DC   +P WAS+N G  +C EC  +HRS G  +S+VR L+   WP  L +
Sbjct: 3   KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62

Query: 531 VMSSIGNELANSIWEGS-------SQGQTKPSIK-STREEKEWWIRSKYEEKLFLAPLPC 582
           ++ ++ N  ANSIWE S         G+ K + +      K  +IR+KY+   F+  LPC
Sbjct: 63  MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122

Query: 583 ------TELSLGQQLLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 636
                 T   L +QL  +    +L+T + LL+ G++           G T LH+A + G 
Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179

Query: 637 VVLEQLL--XGVDVMARDAHGNTALTYARQASSQECINVLLQ 676
           ++  +LL   G D   +D+ G T + YARQ    E    L++
Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221


>gi|17149830 G protein-coupled receptor kinase interacting ArfGAP 2
           isoform 1 [Homo sapiens]
          Length = 759

 Score =  111 bits (277), Expect = 3e-24
 Identities = 71/222 (31%), Positives = 111/222 (50%), Gaps = 19/222 (8%)

Query: 471 QNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRK 530
           + +R +  C DC   +P WAS+N G  +C EC  +HRS G  +S+VR L+   WP  L +
Sbjct: 3   KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62

Query: 531 VMSSIGNELANSIWEGS-------SQGQTKPSIK-STREEKEWWIRSKYEEKLFLAPLPC 582
           ++ ++ N  ANSIWE S         G+ K + +      K  +IR+KY+   F+  LPC
Sbjct: 63  MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122

Query: 583 ------TELSLGQQLLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 636
                 T   L +QL  +    +L+T + LL+ G++           G T LH+A + G 
Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179

Query: 637 VVLEQLL--XGVDVMARDAHGNTALTYARQASSQECINVLLQ 676
           ++  +LL   G D   +D+ G T + YARQ    E    L++
Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221


>gi|17149832 G protein-coupled receptor kinase interacting ArfGAP 2
           isoform 2 [Homo sapiens]
          Length = 631

 Score =  111 bits (277), Expect = 3e-24
 Identities = 71/222 (31%), Positives = 111/222 (50%), Gaps = 19/222 (8%)

Query: 471 QNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRK 530
           + +R +  C DC   +P WAS+N G  +C EC  +HRS G  +S+VR L+   WP  L +
Sbjct: 3   KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62

Query: 531 VMSSIGNELANSIWEGS-------SQGQTKPSIK-STREEKEWWIRSKYEEKLFLAPLPC 582
           ++ ++ N  ANSIWE S         G+ K + +      K  +IR+KY+   F+  LPC
Sbjct: 63  MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122

Query: 583 ------TELSLGQQLLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 636
                 T   L +QL  +    +L+T + LL+ G++           G T LH+A + G 
Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179

Query: 637 VVLEQLL--XGVDVMARDAHGNTALTYARQASSQECINVLLQ 676
           ++  +LL   G D   +D+ G T + YARQ    E    L++
Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221


>gi|206725415 G protein-coupled receptor kinase interacting ArfGAP 2
           isoform 4 [Homo sapiens]
          Length = 471

 Score =  111 bits (277), Expect = 3e-24
 Identities = 71/222 (31%), Positives = 111/222 (50%), Gaps = 19/222 (8%)

Query: 471 QNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRK 530
           + +R +  C DC   +P WAS+N G  +C EC  +HRS G  +S+VR L+   WP  L +
Sbjct: 3   KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62

Query: 531 VMSSIGNELANSIWEGS-------SQGQTKPSIK-STREEKEWWIRSKYEEKLFLAPLPC 582
           ++ ++ N  ANSIWE S         G+ K + +      K  +IR+KY+   F+  LPC
Sbjct: 63  MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122

Query: 583 ------TELSLGQQLLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 636
                 T   L +QL  +    +L+T + LL+ G++           G T LH+A + G 
Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179

Query: 637 VVLEQLL--XGVDVMARDAHGNTALTYARQASSQECINVLLQ 676
           ++  +LL   G D   +D+ G T + YARQ    E    L++
Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221


>gi|146231998 G protein-coupled receptor kinase interactor 1 isoform
           1 [Homo sapiens]
          Length = 770

 Score =  107 bits (268), Expect = 3e-23
 Identities = 70/214 (32%), Positives = 107/214 (50%), Gaps = 19/214 (8%)

Query: 479 CVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNE 538
           C DC   +P WAS++ GVL+C EC  +HRS G  +S V+ L    WP  L +++ ++ + 
Sbjct: 11  CADCSAPDPGWASISRGVLVCDECCSVHRSLGRHISIVKHLRHSAWPPTLLQMVHTLASN 70

Query: 539 LANSIWEGS-------SQGQTKPSIK-STREEKEWWIRSKYEEKLFLAPLPC------TE 584
            ANSIWE S         G+ K + +      K  +IR+KY+   F+  LPC      T 
Sbjct: 71  GANSIWEHSLLDPAQVQSGRRKANPQDKVHPIKSEFIRAKYQMLAFVHKLPCRDDDGVTA 130

Query: 585 LSLGQQLLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLL- 643
             L +QL  +    +L+T + LL+ G++           G T LH+A + G  +  +LL 
Sbjct: 131 KDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGTTPLHVAAKAGQTLQAELLV 187

Query: 644 -XGVDVMARDAHGNTALTYARQASSQECINVLLQ 676
             G D  + D +G T + YARQA   E    L++
Sbjct: 188 VYGADPGSPDVNGRTPIDYARQAGHHELAERLVE 221


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.127    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,806,270
Number of Sequences: 37866
Number of extensions: 1234174
Number of successful extensions: 5131
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 131
Number of HSP's successfully gapped in prelim test: 198
Number of HSP's that attempted gapping in prelim test: 4345
Number of HSP's gapped (non-prelim): 813
length of query: 684
length of database: 18,247,518
effective HSP length: 109
effective length of query: 575
effective length of database: 14,120,124
effective search space: 8119071300
effective search space used: 8119071300
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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