Guide to the Human Genome
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Search of human proteins with 239743762

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239743762 PREDICTED: hypothetical protein XP_002342954 [Homo
sapiens]
         (183 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239743762 PREDICTED: hypothetical protein XP_002342954 [Homo ...   363   e-101
gi|149363632 coiled-coil domain containing 29 [Homo sapiens]          311   2e-85
gi|169217383 PREDICTED: similar to coiled-coil domain containing...   275   1e-74
gi|169178850 PREDICTED: similar to coiled-coil domain containing...   270   4e-73
gi|239750312 PREDICTED: similar to hCG1744891 [Homo sapiens]          255   2e-68
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]      228   2e-60
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]      228   2e-60
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]      228   2e-60
gi|239747109 PREDICTED: hypothetical protein XP_002344496 [Homo ...   226   8e-60
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]      224   4e-59
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]      224   4e-59
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]      224   4e-59
gi|239742325 PREDICTED: similar to coiled-coil domain containing...   195   2e-50
gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens]    165   2e-41
gi|154354990 ankyrin repeat domain 26 [Homo sapiens]                  151   3e-37
gi|169169660 PREDICTED: hypothetical protein [Homo sapiens]           100   7e-22
gi|169169929 PREDICTED: hypothetical protein [Homo sapiens]           100   7e-22
gi|149363642 coiled-coil domain containing 144A [Homo sapiens]         84   9e-17
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ...    50   8e-07
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]                   50   1e-06
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...    46   2e-05
gi|217272804 hyaluronan-mediated motility receptor isoform d [Ho...    46   2e-05
gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho...    46   2e-05
gi|217416398 hyaluronan-mediated motility receptor isoform c [Ho...    46   2e-05
gi|217416394 hyaluronan-mediated motility receptor isoform b [Ho...    46   2e-05
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             45   3e-05
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...    45   3e-05
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]    44   6e-05
gi|71061468 centromere protein E [Homo sapiens]                        44   6e-05
gi|187761324 shootin1 isoform a [Homo sapiens]                         44   8e-05

>gi|239743762 PREDICTED: hypothetical protein XP_002342954 [Homo
           sapiens]
          Length = 183

 Score =  363 bits (932), Expect = e-101
 Identities = 183/183 (100%), Positives = 183/183 (100%)

Query: 1   MRHRPQRRNYFKWKVKYKKLLEMTINMLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKF 60
           MRHRPQRRNYFKWKVKYKKLLEMTINMLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKF
Sbjct: 1   MRHRPQRRNYFKWKVKYKKLLEMTINMLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKF 60

Query: 61  DDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHME 120
           DDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHME
Sbjct: 61  DDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHME 120

Query: 121 NNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQMELDCVEQITRETKRIVAVLNTCSRLL 180
           NNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQMELDCVEQITRETKRIVAVLNTCSRLL
Sbjct: 121 NNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQMELDCVEQITRETKRIVAVLNTCSRLL 180

Query: 181 TSL 183
           TSL
Sbjct: 181 TSL 183


>gi|149363632 coiled-coil domain containing 29 [Homo sapiens]
          Length = 161

 Score =  311 bits (797), Expect = 2e-85
 Identities = 157/161 (97%), Positives = 160/161 (99%)

Query: 23  MTINMLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQ 82
           MTINMLNVFGNEDFDCHGDLK DQLKMDILIKKLKQKFDDLTA+KEALSSKCVNLAKDNQ
Sbjct: 1   MTINMLNVFGNEDFDCHGDLKTDQLKMDILIKKLKQKFDDLTAQKEALSSKCVNLAKDNQ 60

Query: 83  VLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQ 142
           VLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVE+SKLQEYKLELDEKAMQ
Sbjct: 61  VLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVEISKLQEYKLELDEKAMQ 120

Query: 143 AVEKIEEIHLQMELDCVEQITRETKRIVAVLNTCSRLLTSL 183
           AVEK+EEIHLQMELDCVEQITRETKRIVAVLNTCSRLLTSL
Sbjct: 121 AVEKLEEIHLQMELDCVEQITRETKRIVAVLNTCSRLLTSL 161


>gi|169217383 PREDICTED: similar to coiled-coil domain containing 29
           [Homo sapiens]
          Length = 185

 Score =  275 bits (704), Expect = 1e-74
 Identities = 139/161 (86%), Positives = 149/161 (92%)

Query: 23  MTINMLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQ 82
           MTINMLNVFGNEDF CH DLK DQLKMDILIKKLKQKFDDLT E+EA+SSKCVNLAKDNQ
Sbjct: 1   MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQ 60

Query: 83  VLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQ 142
           V+QQE LSMKKVQQ+CEKLEEDKKML+EEILNLKTHMENN VELSKLQEYK E DE+A+Q
Sbjct: 61  VIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQ 120

Query: 143 AVEKIEEIHLQMELDCVEQITRETKRIVAVLNTCSRLLTSL 183
           AVEK+EEIHLQME DCVEQI RETKR VAVL+TCS LL+SL
Sbjct: 121 AVEKLEEIHLQMEADCVEQIIRETKRTVAVLDTCSHLLSSL 161


>gi|169178850 PREDICTED: similar to coiled-coil domain containing 29
           [Homo sapiens]
          Length = 197

 Score =  270 bits (691), Expect = 4e-73
 Identities = 136/161 (84%), Positives = 150/161 (93%)

Query: 23  MTINMLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQ 82
           MTINMLNVFGNEDF CH DLK DQLKMDILIKKLKQKFDDL AE+EA+SSKCVNL+KDNQ
Sbjct: 1   MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60

Query: 83  VLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQ 142
           V+QQE LSMKKVQQ+CEKLEE++KML+EEILNLKTHMEN+ VELSKLQEYK ELDE+AMQ
Sbjct: 61  VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120

Query: 143 AVEKIEEIHLQMELDCVEQITRETKRIVAVLNTCSRLLTSL 183
           AVEK++EIHLQMELDCVEQI RETKR VAVL+TC  LL+SL
Sbjct: 121 AVEKLKEIHLQMELDCVEQIIRETKRTVAVLDTCCHLLSSL 161


>gi|239750312 PREDICTED: similar to hCG1744891 [Homo sapiens]
          Length = 154

 Score =  255 bits (651), Expect = 2e-68
 Identities = 128/146 (87%), Positives = 136/146 (93%)

Query: 23  MTINMLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQ 82
           MTINMLNVFGNEDF CH DLK DQLKMDILIKKLKQKFDDLT E+EA+SSKCVNLAKDNQ
Sbjct: 1   MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQ 60

Query: 83  VLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQ 142
           V+QQE LSMKKVQQ+CEKLEEDKKML+EEILNLKTHMENN VELSKLQEYK E DE+A+Q
Sbjct: 61  VIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSEPDERAIQ 120

Query: 143 AVEKIEEIHLQMELDCVEQITRETKR 168
           AVEK+EEIHLQME DCVEQI RETKR
Sbjct: 121 AVEKLEEIHLQMEADCVEQIIRETKR 146


>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
          Length = 1363

 Score =  228 bits (581), Expect = 2e-60
 Identities = 115/170 (67%), Positives = 135/170 (79%)

Query: 4   RPQRRNYFKWKVKYKKLLEMTINMLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKFDDL 63
           R + R   +    YKK LEMTINMLN F NEDF CHGDL  DQLKMDIL KKLKQKFDDL
Sbjct: 802 RKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDL 861

Query: 64  TAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNR 123
            AEKEA+SSKCVNLAKDN+VL QE LSM KVQ++CEKLE+DKKML+E++LNLKTHME + 
Sbjct: 862 MAEKEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDM 921

Query: 124 VELSKLQEYKLELDEKAMQAVEKIEEIHLQMELDCVEQITRETKRIVAVL 173
           VEL K+QEYK ELDE+AMQA+EK+EEIHLQ + +  +Q+ +  K   A L
Sbjct: 922 VELGKVQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASL 971


>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
          Length = 1366

 Score =  228 bits (581), Expect = 2e-60
 Identities = 115/170 (67%), Positives = 135/170 (79%)

Query: 4    RPQRRNYFKWKVKYKKLLEMTINMLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKFDDL 63
            R + R   +    YKK LEMTINMLN F NEDF CHGDL  DQLKMDIL KKLKQKFDDL
Sbjct: 831  RKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDL 890

Query: 64   TAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNR 123
             AEKEA+SSKCVNLAKDN+VL QE LSM KVQ++CEKLE+DKKML+E++LNLKTHME + 
Sbjct: 891  MAEKEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDM 950

Query: 124  VELSKLQEYKLELDEKAMQAVEKIEEIHLQMELDCVEQITRETKRIVAVL 173
            VEL K+QEYK ELDE+AMQA+EK+EEIHLQ + +  +Q+ +  K   A L
Sbjct: 951  VELGKVQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASL 1000


>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
          Length = 1139

 Score =  228 bits (581), Expect = 2e-60
 Identities = 115/170 (67%), Positives = 135/170 (79%)

Query: 4    RPQRRNYFKWKVKYKKLLEMTINMLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKFDDL 63
            R + R   +    YKK LEMTINMLN F NEDF CHGDL  DQLKMDIL KKLKQKFDDL
Sbjct: 831  RKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDL 890

Query: 64   TAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNR 123
             AEKEA+SSKCVNLAKDN+VL QE LSM KVQ++CEKLE+DKKML+E++LNLKTHME + 
Sbjct: 891  MAEKEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDM 950

Query: 124  VELSKLQEYKLELDEKAMQAVEKIEEIHLQMELDCVEQITRETKRIVAVL 173
            VEL K+QEYK ELDE+AMQA+EK+EEIHLQ + +  +Q+ +  K   A L
Sbjct: 951  VELGKVQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASL 1000


>gi|239747109 PREDICTED: hypothetical protein XP_002344496 [Homo
           sapiens]
          Length = 146

 Score =  226 bits (576), Expect = 8e-60
 Identities = 114/139 (82%), Positives = 128/139 (92%), Gaps = 2/139 (1%)

Query: 23  MTINMLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQ 82
           MTINMLNVFGNEDF CH DLK DQLKMDILIKKLKQKFDDL AE+EA+SSKCVNL+KDNQ
Sbjct: 1   MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60

Query: 83  VLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQ 142
           V+QQE LSMKKVQQ+CEKLEE++KML+EEILNLKTHMEN+ VELSKLQEYK ELDE+AMQ
Sbjct: 61  VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120

Query: 143 AVEKIEEIHLQMELDCVEQ 161
           AVEK++EIHLQ  + C+ Q
Sbjct: 121 AVEKLKEIHLQ--VTCLNQ 137


>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
          Length = 1415

 Score =  224 bits (570), Expect = 4e-59
 Identities = 112/170 (65%), Positives = 134/170 (78%)

Query: 4   RPQRRNYFKWKVKYKKLLEMTINMLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKFDDL 63
           R + R   +    YKK LEMTINMLN F NEDF CHGDL  DQLKMDIL KKLKQKF+DL
Sbjct: 801 RKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDL 860

Query: 64  TAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNR 123
            AEKEA+SS+CVNLAKDN+VL QE LSM+ VQ++CEKLE+DKKML+EE+LNLKTHME + 
Sbjct: 861 VAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDM 920

Query: 124 VELSKLQEYKLELDEKAMQAVEKIEEIHLQMELDCVEQITRETKRIVAVL 173
           VEL KLQEYK ELDE+A+Q +EK+EEIHLQ + +  +Q+ +  K   A L
Sbjct: 921 VELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASL 970


>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
          Length = 1002

 Score =  224 bits (570), Expect = 4e-59
 Identities = 112/170 (65%), Positives = 134/170 (78%)

Query: 4   RPQRRNYFKWKVKYKKLLEMTINMLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKFDDL 63
           R + R   +    YKK LEMTINMLN F NEDF CHGDL  DQLKMDIL KKLKQKF+DL
Sbjct: 694 RKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDL 753

Query: 64  TAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNR 123
            AEKEA+SS+CVNLAKDN+VL QE LSM+ VQ++CEKLE+DKKML+EE+LNLKTHME + 
Sbjct: 754 VAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDM 813

Query: 124 VELSKLQEYKLELDEKAMQAVEKIEEIHLQMELDCVEQITRETKRIVAVL 173
           VEL KLQEYK ELDE+A+Q +EK+EEIHLQ + +  +Q+ +  K   A L
Sbjct: 814 VELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASL 863


>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
          Length = 1415

 Score =  224 bits (570), Expect = 4e-59
 Identities = 112/170 (65%), Positives = 134/170 (78%)

Query: 4   RPQRRNYFKWKVKYKKLLEMTINMLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKFDDL 63
           R + R   +    YKK LEMTINMLN F NEDF CHGDL  DQLKMDIL KKLKQKF+DL
Sbjct: 801 RKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDL 860

Query: 64  TAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNR 123
            AEKEA+SS+CVNLAKDN+VL QE LSM+ VQ++CEKLE+DKKML+EE+LNLKTHME + 
Sbjct: 861 VAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDM 920

Query: 124 VELSKLQEYKLELDEKAMQAVEKIEEIHLQMELDCVEQITRETKRIVAVL 173
           VEL KLQEYK ELDE+A+Q +EK+EEIHLQ + +  +Q+ +  K   A L
Sbjct: 921 VELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASL 970


>gi|239742325 PREDICTED: similar to coiled-coil domain containing 29
           [Homo sapiens]
          Length = 150

 Score =  195 bits (495), Expect = 2e-50
 Identities = 97/125 (77%), Positives = 115/125 (92%)

Query: 59  KFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTH 118
           +FDDL AE+EA+SSKCVNLAKDNQV+QQE LSMKKVQQ+CEKLEE++KML+EEILNLKTH
Sbjct: 2   RFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH 61

Query: 119 MENNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQMELDCVEQITRETKRIVAVLNTCSR 178
           MEN+ VELS+LQ+YK ELDE+AMQAVEK++EI+L ME DC+EQI RETKR  AVL+TCS 
Sbjct: 62  MENSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIRETKRTAAVLDTCSH 121

Query: 179 LLTSL 183
           LL+SL
Sbjct: 122 LLSSL 126


>gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens]
          Length = 561

 Score =  165 bits (417), Expect = 2e-41
 Identities = 83/116 (71%), Positives = 100/116 (86%)

Query: 55  KLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEILN 114
           +++ +FDD  AEKEA+SSKCVNLAK+ QV QQE LSMKKVQQ+CEKLEEDKKML+EEILN
Sbjct: 443 QVESQFDDFMAEKEAVSSKCVNLAKEIQVFQQELLSMKKVQQECEKLEEDKKMLEEEILN 502

Query: 115 LKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQMELDCVEQITRETKRIV 170
           LKTHMEN+ VELSKLQEYK ELDE+AMQAVEK+EEIHLQ + +  +Q+ +  K I+
Sbjct: 503 LKTHMENSMVELSKLQEYKSELDERAMQAVEKLEEIHLQEQAEHKKQLEQLNKDII 558


>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
          Length = 1710

 Score =  151 bits (382), Expect = 3e-37
 Identities = 74/153 (48%), Positives = 109/153 (71%), Gaps = 1/153 (0%)

Query: 17   YKKLLEMTINMLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVN 76
            +K LL+MT   LN + N +F  HGDLK  Q +MDI I KLK K DDLTAE E   SKC++
Sbjct: 1363 FKNLLKMTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLH 1422

Query: 77   LAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLEL 136
            L   NQ+LQ+E LSMK VQ++CEKL+++KK L++E++NL++H+E N VEL ++++YK E+
Sbjct: 1423 LDTKNQILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEI 1482

Query: 137  DEKAMQAV-EKIEEIHLQMELDCVEQITRETKR 168
            +E+A Q + EK++E++L ++     Q   E  R
Sbjct: 1483 EERARQEIAEKLKEVNLFLQAQAASQENLEQFR 1515



 Score = 26.9 bits (58), Expect = 9.8
 Identities = 26/111 (23%), Positives = 47/111 (42%), Gaps = 12/111 (10%)

Query: 38   CHGDLKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQ 97
            C  DLK  + K + L K +KQ  + LT      + +   L  +N +L  +  + K+ +++
Sbjct: 942  CFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKER 1001

Query: 98   CEKLEE-----------DKKMLKEEILNLKTHMENNRVELSKLQEYKLELD 137
             E   E           D+   +     L+   +  R E S+LQ+ K+  D
Sbjct: 1002 LEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQD-KMNFD 1051


>gi|169169660 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 460

 Score =  100 bits (249), Expect = 7e-22
 Identities = 52/100 (52%), Positives = 74/100 (74%), Gaps = 1/100 (1%)

Query: 54  KKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEIL 113
           K L++   +L    +    KC+ LAK NQV+QQE LSMK+VQQ+C+KLEE  K+L++E++
Sbjct: 316 KFLRRHLMNLQQSWKLYLQKCLYLAKKNQVIQQELLSMKEVQQKCKKLEEVNKILEQEVV 375

Query: 114 NLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQ 153
           NLKTH E N VE   ++E KL+L+E+A Q +EK+EEI+LQ
Sbjct: 376 NLKTH-EKNMVEFGDVEECKLQLEERAGQEIEKLEEINLQ 414


>gi|169169929 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 460

 Score =  100 bits (249), Expect = 7e-22
 Identities = 52/100 (52%), Positives = 74/100 (74%), Gaps = 1/100 (1%)

Query: 54  KKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEIL 113
           K L++   +L    +    KC+ LAK NQV+QQE LSMK+VQQ+C+KLEE  K+L++E++
Sbjct: 316 KFLRRHLMNLQQSWKLYLQKCLYLAKKNQVIQQELLSMKEVQQKCKKLEEVNKILEQEVV 375

Query: 114 NLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQ 153
           NLKTH E N VE   ++E KL+L+E+A Q +EK+EEI+LQ
Sbjct: 376 NLKTH-EKNMVEFGDVEECKLQLEERAGQEIEKLEEINLQ 414


>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
          Length = 1427

 Score = 83.6 bits (205), Expect = 9e-17
 Identities = 44/111 (39%), Positives = 75/111 (67%), Gaps = 3/111 (2%)

Query: 48   KMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQ--QEFLSMKKVQQQCEKLEEDK 105
            +MD   K+   +  DLT  +E + S+C++L  +N+VLQ  Q   SMK +Q+QCE L+++K
Sbjct: 1112 RMDQCEKEKAGRKIDLTEAQETVPSRCLHLDAENEVLQLQQTLFSMKAIQKQCETLQKNK 1171

Query: 106  KMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAV-EKIEEIHLQME 155
            K LK+E++NLK++ME N +E  K + +KL ++E+A + + EK+ E  L ++
Sbjct: 1172 KQLKQEVVNLKSYMERNMLERGKAEWHKLLIEERARKEIEEKLNEAILTLQ 1222



 Score = 28.5 bits (62), Expect = 3.4
 Identities = 29/136 (21%), Positives = 65/136 (47%), Gaps = 15/136 (11%)

Query: 46  QLKMDI--LIKKLKQKFD--DLTAEKEALSSKCVNLAKDNQVLQQEFLSMK--------- 92
           QLK ++  L+K+L+   +  DL  ++   + K ++  +D ++LQ + L+ K         
Sbjct: 742 QLKWNLRRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTSKQKELEMARK 801

Query: 93  KVQQQCEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEE--I 150
           K+  +     + +K L  E   L+  +   R+E+  ++    + ++K  + +E ++E   
Sbjct: 802 KMNSEISHRHQKEKDLFHEDCMLQEEIALLRLEIDTIKNQNKQKEKKYFEDIEAVKEKND 861

Query: 151 HLQMELDCVEQITRET 166
           +LQ  +   E+   ET
Sbjct: 862 NLQKIIKLNEETLTET 877


>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
            sapiens]
          Length = 1939

 Score = 50.4 bits (119), Expect = 8e-07
 Identities = 33/131 (25%), Positives = 66/131 (50%), Gaps = 6/131 (4%)

Query: 41   DLKADQLKMDILIK---KLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQ 97
            DL+ ++ K++ L K   KL+Q+ DDL    E     C++L +  + L+ +   +K  Q+ 
Sbjct: 1013 DLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGD---LKLAQES 1069

Query: 98   CEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQMELD 157
                E DK+ L E++   +  M N + ++   Q   ++L +K  +   +IEE+  ++E +
Sbjct: 1070 TMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAE 1129

Query: 158  CVEQITRETKR 168
               +   E +R
Sbjct: 1130 RASRAKAEKQR 1140



 Score = 47.0 bits (110), Expect = 9e-06
 Identities = 32/120 (26%), Positives = 53/120 (44%), Gaps = 9/120 (7%)

Query: 54   KKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQE----FLSMKKVQQQCEKLEEDKKMLK 109
            KKL Q+  D     EA++SKC +L K  Q LQ E     + +++    C  L++ ++   
Sbjct: 1395 KKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFD 1454

Query: 110  EEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQMELDCVEQITRETKRI 169
            + +   K   E  + EL   Q+    L  +  +     EE      LD +E + RE K +
Sbjct: 1455 KVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEE-----SLDHLETLKRENKNL 1509



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 46/178 (25%), Positives = 78/178 (43%), Gaps = 35/178 (19%)

Query: 12   KWKVKYKKLLEMTINM--------LNVFGNEDFDCHGDLKADQL-----KMDILIKKLKQ 58
            K + K K+L E  + +        L V    D     + + DQL     +++  IK++ +
Sbjct: 869  KTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTE 928

Query: 59   KFDD-------LTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEE 111
            + +D       LTA+K  L  +C  L KD   L+   L++ KV+++    E   K L EE
Sbjct: 929  RAEDEEEINAELTAKKRKLEDECSELKKDIDDLE---LTLAKVEKEKHATENKVKNLTEE 985

Query: 112  ILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQMELDCVEQITRETKRI 169
            +  L          ++KL + K  L E   Q ++      LQME D V  +T+   ++
Sbjct: 986  MAGLDE-------TIAKLTKEKKALQEAHQQTLDD-----LQMEEDKVNTLTKAKTKL 1031



 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 28/118 (23%), Positives = 55/118 (46%), Gaps = 11/118 (9%)

Query: 42   LKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQC--- 98
            L   Q   D ++ + KQK+++  AE EA         K+++ L  E   +K   ++    
Sbjct: 1446 LDKKQRNFDKVLAEWKQKYEETQAELEASQ-------KESRSLSTELFKVKNAYEESLDH 1498

Query: 99   -EKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQME 155
             E L+ + K L++EI +L   +      + +L++ K +LD +  +    +EE    +E
Sbjct: 1499 LETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLE 1556



 Score = 33.1 bits (74), Expect = 0.14
 Identities = 13/49 (26%), Positives = 31/49 (63%)

Query: 109 KEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQMELD 157
           ++E+ N+K   E  + EL+K +  + EL+EK +  +++  ++ LQ++ +
Sbjct: 850 EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898



 Score = 32.7 bits (73), Expect = 0.18
 Identities = 25/103 (24%), Positives = 54/103 (52%), Gaps = 4/103 (3%)

Query: 48   KMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQV-LQQEFLSMKKVQQQCEKLEEDKK 106
            K +   +K+++  ++ T + EA ++       D+   L ++  S+++V+Q   KLE++K 
Sbjct: 1170 KREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQ---KLEKEKS 1226

Query: 107  MLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEE 149
             LK EI +L ++ME      +  ++    L+++  +   K EE
Sbjct: 1227 ELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEE 1269



 Score = 29.6 bits (65), Expect = 1.5
 Identities = 25/141 (17%), Positives = 66/141 (46%), Gaps = 13/141 (9%)

Query: 15   VKYKKLLEMTINMLNVFGNEDFDCHGDLKADQLKMDI-----LIKKLKQKFDDLTAEKEA 69
            ++ KK +E  +N + +  N     H + +A +   ++     ++K  +   DD    ++ 
Sbjct: 1616 LRIKKKMEGDLNEMEIQLN-----HANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDD 1670

Query: 70   LSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVELSKL 129
            L  +   + +   ++Q E   +++++   E+ E  +KM ++E+L+    ++    + + L
Sbjct: 1671 LKEQLAMVERRANLMQAE---VEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSL 1727

Query: 130  QEYKLELDEKAMQAVEKIEEI 150
               K +L+    Q   ++E+I
Sbjct: 1728 INTKKKLETDISQIQGEMEDI 1748



 Score = 28.9 bits (63), Expect = 2.6
 Identities = 22/94 (23%), Positives = 47/94 (50%), Gaps = 4/94 (4%)

Query: 56   LKQKFDDLTAEKEALSSKCVNLAKDN-QVLQQEFLSMKKVQQQCEKLEEDKKMLKEEILN 114
            L++++++   E+EA +     ++K N +V Q          Q+ E+LEE KK L + + +
Sbjct: 1347 LREQYEE---EQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQD 1403

Query: 115  LKTHMENNRVELSKLQEYKLELDEKAMQAVEKIE 148
             + H+E    + + L++ K  L  +    +  +E
Sbjct: 1404 AEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVE 1437



 Score = 28.5 bits (62), Expect = 3.4
 Identities = 28/125 (22%), Positives = 54/125 (43%), Gaps = 18/125 (14%)

Query: 18   KKLLEMTINMLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNL 77
            +KL +    M N+ G  +     D +A  +++   IK+L+ + ++L  E EA  +     
Sbjct: 1082 EKLKKKEFEMSNLQGKIE-----DEQALAIQLQKKIKELQARIEELEEEIEAERASRAKA 1136

Query: 78   AKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELD 137
             K    L +E             LEE  + L+E        +E N+   ++ Q+ + +L+
Sbjct: 1137 EKQRSDLSRE-------------LEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLE 1183

Query: 138  EKAMQ 142
            E  +Q
Sbjct: 1184 ESTLQ 1188


>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
          Length = 1417

 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 40/176 (22%), Positives = 90/176 (51%), Gaps = 13/176 (7%)

Query: 20   LLEMTINMLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKFD---DLTAEK-EALSSKCV 75
            +L+ T+        ++   +G+L+  Q K++  + KL+Q+     + +AEK   +  KC 
Sbjct: 906  ILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCE 965

Query: 76   NLAKDNQVLQQEFLSM----KKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVELSK--- 128
            + A +  + +Q+ + +    ++V+ + ++ +E+   +++EI++LK   EN  + LS+   
Sbjct: 966  SAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDM 1025

Query: 129  -LQEYKLELDEKAMQAVEKIEEIHLQMELDCVEQITRETKRIVAVLNTCSRLLTSL 183
             L + K EL EK   AV+++E++    E +  E + +       + N    L ++L
Sbjct: 1026 ILDQTKTEL-EKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTL 1080



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 30/113 (26%), Positives = 56/113 (49%), Gaps = 14/113 (12%)

Query: 54  KKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEIL 113
           KK+ +K + + AE+E L     N  K+N          K++Q++C   + + ++LKE++ 
Sbjct: 375 KKVAEKLEKVQAEEEILERNLTNCEKEN----------KRLQERCGLYKSELEILKEKLR 424

Query: 114 NLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEI-HLQMELDCVEQITRE 165
            LK    N +    KL+   ++  E   Q  E  + I  L+ EL+  ++I R+
Sbjct: 425 QLKEENNNGK---EKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEILRD 474



 Score = 37.4 bits (85), Expect = 0.007
 Identities = 24/105 (22%), Positives = 45/105 (42%), Gaps = 3/105 (2%)

Query: 53  IKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEI 112
           I++L+ K   + AE   L     +     Q++Q+E L          KLE +      ++
Sbjct: 643 IEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKAS---NSSKLESEMTKKCSQL 699

Query: 113 LNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQMELD 157
           L L+  +E   V  S +     EL+++ M+  EKI  +   +  +
Sbjct: 700 LTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTE 744



 Score = 35.4 bits (80), Expect = 0.028
 Identities = 26/130 (20%), Positives = 60/130 (46%), Gaps = 18/130 (13%)

Query: 39  HGDLKADQL----KMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKV 94
           + DLK +      +  ++ ++L +K  + +  +  ++ KC  L    + L+++ ++   +
Sbjct: 657 NSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSI 716

Query: 95  QQQCEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQM 154
             +  +LE++     E+I +L+T++                  EK   A EK ++IHL+ 
Sbjct: 717 AAKNAELEQELMEKNEKIRSLETNINTEH--------------EKICLAFEKAKKIHLEQ 762

Query: 155 ELDCVEQITR 164
             +  +QI R
Sbjct: 763 HKEMEKQIER 772



 Score = 33.1 bits (74), Expect = 0.14
 Identities = 28/115 (24%), Positives = 57/115 (49%), Gaps = 9/115 (7%)

Query: 41   DLKADQLKMDILIKK----LKQKFDDLT----AEKEALSSKCVNLAKDNQVLQQEFLSMK 92
            D K + L+MD  +K+    LKQ+   +T      +E        + K    L++  L +K
Sbjct: 1120 DKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELK 1179

Query: 93   KVQQQCEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKI 147
            +  +Q E L +  +  KE++   +  M  N  E+S+L++ ++E  ++ M+ +E +
Sbjct: 1180 ECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKK-EIERTQQRMKEMESV 1233



 Score = 28.1 bits (61), Expect = 4.4
 Identities = 20/106 (18%), Positives = 54/106 (50%), Gaps = 3/106 (2%)

Query: 41   DLKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMK-KVQQQCE 99
            D+  DQ K ++  +K      +L   + +  ++     +  +VL+ E  +   +++    
Sbjct: 1024 DMILDQTKTEL--EKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLR 1081

Query: 100  KLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVE 145
            +L+E + +L++  L+L+      +   ++L+E K+E+++K  + +E
Sbjct: 1082 QLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLE 1127


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 9/120 (7%)

Query: 54   KKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQE----FLSMKKVQQQCEKLEEDKKMLK 109
            KKL Q+  D     EA+++KC +L K  Q LQ E     + +++    C  L++ ++   
Sbjct: 1395 KKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFD 1454

Query: 110  EEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQMELDCVEQITRETKRI 169
            + +   K   E    EL   Q+    L  +  +     EE      LD +E + RE K +
Sbjct: 1455 KILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEE-----SLDQLETLKRENKNL 1509



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 49/195 (25%), Positives = 84/195 (43%), Gaps = 30/195 (15%)

Query: 12   KWKVKYKKLLEMTINM--------LNVFGNEDFDCHGDLKADQL-----KMDILIKKLKQ 58
            K + K K+L E  + +        L V    D     + + DQL     +++  IK++ +
Sbjct: 869  KTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTE 928

Query: 59   KFDD-------LTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEE 111
            + +D       LTA+K  L  +C  L KD   L+   L++ KV+++    E   K L EE
Sbjct: 929  RAEDEEEINAELTAKKRKLEDECSELKKDIDDLE---LTLAKVEKEKHATENKVKNLTEE 985

Query: 112  ILNLKTHMENNRVELSKLQEY------KLELDEKAMQAVEKIEEIHLQMELDCVEQITRE 165
            +  L   +     E   LQE        L+ +E  +  + K  +I L+ ++D +E    +
Sbjct: 986  MAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTK-AKIKLEQQVDDLEGSLEQ 1044

Query: 166  TKRIVAVLNTCSRLL 180
             K+I   L    R L
Sbjct: 1045 EKKIRMDLERAKRKL 1059



 Score = 38.5 bits (88), Expect = 0.003
 Identities = 27/118 (22%), Positives = 55/118 (46%), Gaps = 11/118 (9%)

Query: 42   LKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQ----Q 97
            L   Q   D ++ + KQK ++  AE EA         K+++ L  E   +K   +    Q
Sbjct: 1446 LDKKQRNFDKILAEWKQKCEETHAELEASQ-------KESRSLSTELFKIKNAYEESLDQ 1498

Query: 98   CEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQME 155
             E L+ + K L++EI +L   +      + +L++ K +++++  +    +EE    +E
Sbjct: 1499 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLE 1556



 Score = 35.4 bits (80), Expect = 0.028
 Identities = 39/137 (28%), Positives = 68/137 (49%), Gaps = 32/137 (23%)

Query: 41   DLKADQLKMDILIK---KLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQ 97
            DL+A++ K++ L K   KL+Q+ DDL                    L+QE      +++ 
Sbjct: 1013 DLQAEEDKVNTLTKAKIKLEQQVDDLEGS-----------------LEQEKKIRMDLERA 1055

Query: 98   CEKLEEDKKMLKEEILNLKT-------HMENNRVELSKLQEYKLELDEKA--MQAVEKIE 148
              KLE D K+ +E  ++++         ++    E+S LQ  K+E DE+A  MQ  +KI+
Sbjct: 1056 KRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQS-KIE-DEQALGMQLQKKIK 1113

Query: 149  EIHLQMELDCVEQITRE 165
            E+  ++E +  E+I  E
Sbjct: 1114 ELQARIE-ELEEEIEAE 1129



 Score = 33.1 bits (74), Expect = 0.14
 Identities = 13/49 (26%), Positives = 31/49 (63%)

Query: 109 KEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQMELD 157
           ++E+ N+K   E  + EL+K +  + EL+EK +  +++  ++ LQ++ +
Sbjct: 850 EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898



 Score = 33.1 bits (74), Expect = 0.14
 Identities = 24/136 (17%), Positives = 61/136 (44%), Gaps = 3/136 (2%)

Query: 15   VKYKKLLEMTINMLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKFDDLTAEKEALSSKC 74
            ++ KK +E  +N + +  N       +   +      ++K  +   DD    +E L  + 
Sbjct: 1616 IRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQL 1675

Query: 75   VNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKL 134
              + +   +LQ E   +++++   E+ E  +K+ ++E+L+    ++    + + L   K 
Sbjct: 1676 AMVERRANLLQAE---IEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKK 1732

Query: 135  ELDEKAMQAVEKIEEI 150
            +L+    Q   ++E+I
Sbjct: 1733 KLETDISQIQGEMEDI 1748



 Score = 32.0 bits (71), Expect = 0.30
 Identities = 24/103 (23%), Positives = 54/103 (52%), Gaps = 4/103 (3%)

Query: 48   KMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQV-LQQEFLSMKKVQQQCEKLEEDKK 106
            K +   +K+++  ++ T + EA ++       D+   L ++  ++++V+Q   KLE++K 
Sbjct: 1170 KREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQ---KLEKEKS 1226

Query: 107  MLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEE 149
             +K EI +L ++ME        L++    L+++  +   K EE
Sbjct: 1227 EMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEE 1269



 Score = 29.6 bits (65), Expect = 1.5
 Identities = 27/117 (23%), Positives = 53/117 (45%), Gaps = 15/117 (12%)

Query: 41   DLKADQLKMDILIKK-------LKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKK 93
            D++ D+ ++D  +KK       L+ K +D  A    L  K   L    + L++E  + + 
Sbjct: 1072 DIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERA 1131

Query: 94   VQQQCEK--------LEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQ 142
             + + EK        LEE  + L+E        +E N+   ++ Q+ + +L+E  +Q
Sbjct: 1132 SRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQ 1188



 Score = 28.9 bits (63), Expect = 2.6
 Identities = 22/94 (23%), Positives = 47/94 (50%), Gaps = 4/94 (4%)

Query: 56   LKQKFDDLTAEKEALSSKCVNLAKDN-QVLQQEFLSMKKVQQQCEKLEEDKKMLKEEILN 114
            L++++++   E+EA +     ++K N +V Q          Q+ E+LEE KK L + + +
Sbjct: 1347 LREQYEE---EQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQD 1403

Query: 115  LKTHMENNRVELSKLQEYKLELDEKAMQAVEKIE 148
             + H+E    + + L++ K  L  +    +  +E
Sbjct: 1404 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVE 1437


>gi|217272804 hyaluronan-mediated motility receptor isoform d [Homo
           sapiens]
          Length = 638

 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 34/124 (27%), Positives = 62/124 (50%), Gaps = 4/124 (3%)

Query: 34  EDFDCHGDLKADQLKMDI--LIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEF-LS 90
           E+  C  D + ++ K+DI  L + LK+K D++ + K++L    V L+K  + L  +  L 
Sbjct: 152 EEISCASD-QVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLL 210

Query: 91  MKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEI 150
            K+ +    +  E  + L  E+ NLK      + E  KLQ+ +L++D    Q  E    +
Sbjct: 211 EKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSL 270

Query: 151 HLQM 154
           H ++
Sbjct: 271 HQKL 274



 Score = 37.0 bits (84), Expect = 0.009
 Identities = 39/166 (23%), Positives = 75/166 (45%), Gaps = 19/166 (11%)

Query: 18  KKLLEMTINMLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNL 77
           K L  +++ ++ +    +    G + A Q  M++ ++  ++  ++   +   L  K V++
Sbjct: 75  KNLRILSLELMKLRNKRETKMRG-MMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSI 133

Query: 78  AKDN-------QVLQQEFLSMKKVQQQCEK-------LEEDKKMLKEEILNLKTHMENNR 123
            K+        + L +    +     Q EK       LEE+ K   +EIL+LK  +E N 
Sbjct: 134 EKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENI 193

Query: 124 VELSKLQEYKLELDEKAMQAVEKIEEIHLQMELDCVEQITRETKRI 169
           V LSK  E   +L+ K  Q +EK +E H+    +  E +  E + +
Sbjct: 194 VILSKQVE---DLNVKC-QLLEKEKEDHVNRNREHNENLNAEMQNL 235



 Score = 33.5 bits (75), Expect = 0.10
 Identities = 32/129 (24%), Positives = 60/129 (46%), Gaps = 18/129 (13%)

Query: 42  LKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLS----MKKVQQQ 97
           L+  +L++D L+++ K+    L    + L S    + K+  + ++E       + K+QQ+
Sbjct: 249 LQQKELQIDSLLQQEKELSSSL---HQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQK 305

Query: 98  CEK-------LEEDKKMLKEEILNLKTHMENNRVELSKLQ----EYKLELDEKAMQAVEK 146
            E+       LEE+ K   EE+  L+  ++    EL K      +  L L EK    V+ 
Sbjct: 306 EEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQS 365

Query: 147 IEEIHLQME 155
           +E++  Q E
Sbjct: 366 LEDVTAQFE 374



 Score = 29.3 bits (64), Expect = 2.0
 Identities = 25/135 (18%), Positives = 64/135 (47%), Gaps = 12/135 (8%)

Query: 41  DLKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEF------LSMKKV 94
           DL+ +  KM+  +    ++   L+A    L  + + L + N++L+ +F       +++ +
Sbjct: 21  DLETELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRIL 80

Query: 95  QQQCEKLEEDKK------MLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIE 148
             +  KL   ++      M K+E + +K  +    +E S+ +  +LE    +++  +  E
Sbjct: 81  SLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDE 140

Query: 149 EIHLQMELDCVEQIT 163
           +   +  L+ +E+I+
Sbjct: 141 KSETEKLLEYIEEIS 155


>gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo
           sapiens]
          Length = 725

 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 34/124 (27%), Positives = 62/124 (50%), Gaps = 4/124 (3%)

Query: 34  EDFDCHGDLKADQLKMDI--LIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEF-LS 90
           E+  C  D + ++ K+DI  L + LK+K D++ + K++L    V L+K  + L  +  L 
Sbjct: 239 EEISCASD-QVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLL 297

Query: 91  MKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEI 150
            K+ +    +  E  + L  E+ NLK      + E  KLQ+ +L++D    Q  E    +
Sbjct: 298 EKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSL 357

Query: 151 HLQM 154
           H ++
Sbjct: 358 HQKL 361



 Score = 37.0 bits (84), Expect = 0.009
 Identities = 39/166 (23%), Positives = 75/166 (45%), Gaps = 19/166 (11%)

Query: 18  KKLLEMTINMLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNL 77
           K L  +++ ++ +    +    G + A Q  M++ ++  ++  ++   +   L  K V++
Sbjct: 162 KNLRILSLELMKLRNKRETKMRG-MMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSI 220

Query: 78  AKDN-------QVLQQEFLSMKKVQQQCEK-------LEEDKKMLKEEILNLKTHMENNR 123
            K+        + L +    +     Q EK       LEE+ K   +EIL+LK  +E N 
Sbjct: 221 EKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENI 280

Query: 124 VELSKLQEYKLELDEKAMQAVEKIEEIHLQMELDCVEQITRETKRI 169
           V LSK  E   +L+ K  Q +EK +E H+    +  E +  E + +
Sbjct: 281 VILSKQVE---DLNVKC-QLLEKEKEDHVNRNREHNENLNAEMQNL 322



 Score = 33.5 bits (75), Expect = 0.10
 Identities = 32/129 (24%), Positives = 60/129 (46%), Gaps = 18/129 (13%)

Query: 42  LKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLS----MKKVQQQ 97
           L+  +L++D L+++ K+    L    + L S    + K+  + ++E       + K+QQ+
Sbjct: 336 LQQKELQIDSLLQQEKELSSSL---HQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQK 392

Query: 98  CEK-------LEEDKKMLKEEILNLKTHMENNRVELSKLQ----EYKLELDEKAMQAVEK 146
            E+       LEE+ K   EE+  L+  ++    EL K      +  L L EK    V+ 
Sbjct: 393 EEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQS 452

Query: 147 IEEIHLQME 155
           +E++  Q E
Sbjct: 453 LEDVTAQFE 461



 Score = 29.6 bits (65), Expect = 1.5
 Identities = 32/158 (20%), Positives = 74/158 (46%), Gaps = 14/158 (8%)

Query: 19  KLLEMTIN-MLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNL 77
           K+LE  I  +L   G +D     DL+ +  KM+  +    ++   L+A    L  + + L
Sbjct: 86  KILEKEIRVLLQERGAQDRRIQ-DLETELEKMEARLNAALREKTSLSANNATLEKQLIEL 144

Query: 78  AKDNQVLQQEF------LSMKKVQQQCEKLEEDKK------MLKEEILNLKTHMENNRVE 125
            + N++L+ +F       +++ +  +  KL   ++      M K+E + +K  +    +E
Sbjct: 145 TRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLE 204

Query: 126 LSKLQEYKLELDEKAMQAVEKIEEIHLQMELDCVEQIT 163
            S+ +  +LE    +++  +  E+   +  L+ +E+I+
Sbjct: 205 ESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEIS 242


>gi|217416398 hyaluronan-mediated motility receptor isoform c [Homo
           sapiens]
          Length = 709

 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 34/124 (27%), Positives = 62/124 (50%), Gaps = 4/124 (3%)

Query: 34  EDFDCHGDLKADQLKMDI--LIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEF-LS 90
           E+  C  D + ++ K+DI  L + LK+K D++ + K++L    V L+K  + L  +  L 
Sbjct: 223 EEISCASD-QVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLL 281

Query: 91  MKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEI 150
            K+ +    +  E  + L  E+ NLK      + E  KLQ+ +L++D    Q  E    +
Sbjct: 282 EKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSL 341

Query: 151 HLQM 154
           H ++
Sbjct: 342 HQKL 345



 Score = 37.0 bits (84), Expect = 0.009
 Identities = 39/166 (23%), Positives = 75/166 (45%), Gaps = 19/166 (11%)

Query: 18  KKLLEMTINMLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNL 77
           K L  +++ ++ +    +    G + A Q  M++ ++  ++  ++   +   L  K V++
Sbjct: 146 KNLRILSLELMKLRNKRETKMRG-MMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSI 204

Query: 78  AKDN-------QVLQQEFLSMKKVQQQCEK-------LEEDKKMLKEEILNLKTHMENNR 123
            K+        + L +    +     Q EK       LEE+ K   +EIL+LK  +E N 
Sbjct: 205 EKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENI 264

Query: 124 VELSKLQEYKLELDEKAMQAVEKIEEIHLQMELDCVEQITRETKRI 169
           V LSK  E   +L+ K  Q +EK +E H+    +  E +  E + +
Sbjct: 265 VILSKQVE---DLNVKC-QLLEKEKEDHVNRNREHNENLNAEMQNL 306



 Score = 33.5 bits (75), Expect = 0.10
 Identities = 32/129 (24%), Positives = 60/129 (46%), Gaps = 18/129 (13%)

Query: 42  LKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLS----MKKVQQQ 97
           L+  +L++D L+++ K+    L    + L S    + K+  + ++E       + K+QQ+
Sbjct: 320 LQQKELQIDSLLQQEKELSSSL---HQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQK 376

Query: 98  CEK-------LEEDKKMLKEEILNLKTHMENNRVELSKLQ----EYKLELDEKAMQAVEK 146
            E+       LEE+ K   EE+  L+  ++    EL K      +  L L EK    V+ 
Sbjct: 377 EEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQS 436

Query: 147 IEEIHLQME 155
           +E++  Q E
Sbjct: 437 LEDVTAQFE 445



 Score = 29.3 bits (64), Expect = 2.0
 Identities = 25/135 (18%), Positives = 64/135 (47%), Gaps = 12/135 (8%)

Query: 41  DLKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEF------LSMKKV 94
           DL+ +  KM+  +    ++   L+A    L  + + L + N++L+ +F       +++ +
Sbjct: 92  DLETELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRIL 151

Query: 95  QQQCEKLEEDKK------MLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIE 148
             +  KL   ++      M K+E + +K  +    +E S+ +  +LE    +++  +  E
Sbjct: 152 SLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDE 211

Query: 149 EIHLQMELDCVEQIT 163
           +   +  L+ +E+I+
Sbjct: 212 KSETEKLLEYIEEIS 226


>gi|217416394 hyaluronan-mediated motility receptor isoform b [Homo
           sapiens]
          Length = 724

 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 34/124 (27%), Positives = 62/124 (50%), Gaps = 4/124 (3%)

Query: 34  EDFDCHGDLKADQLKMDI--LIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEF-LS 90
           E+  C  D + ++ K+DI  L + LK+K D++ + K++L    V L+K  + L  +  L 
Sbjct: 238 EEISCASD-QVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLL 296

Query: 91  MKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEI 150
            K+ +    +  E  + L  E+ NLK      + E  KLQ+ +L++D    Q  E    +
Sbjct: 297 EKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSL 356

Query: 151 HLQM 154
           H ++
Sbjct: 357 HQKL 360



 Score = 37.0 bits (84), Expect = 0.009
 Identities = 39/166 (23%), Positives = 75/166 (45%), Gaps = 19/166 (11%)

Query: 18  KKLLEMTINMLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNL 77
           K L  +++ ++ +    +    G + A Q  M++ ++  ++  ++   +   L  K V++
Sbjct: 161 KNLRILSLELMKLRNKRETKMRG-MMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSI 219

Query: 78  AKDN-------QVLQQEFLSMKKVQQQCEK-------LEEDKKMLKEEILNLKTHMENNR 123
            K+        + L +    +     Q EK       LEE+ K   +EIL+LK  +E N 
Sbjct: 220 EKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENI 279

Query: 124 VELSKLQEYKLELDEKAMQAVEKIEEIHLQMELDCVEQITRETKRI 169
           V LSK  E   +L+ K  Q +EK +E H+    +  E +  E + +
Sbjct: 280 VILSKQVE---DLNVKC-QLLEKEKEDHVNRNREHNENLNAEMQNL 321



 Score = 33.5 bits (75), Expect = 0.10
 Identities = 32/129 (24%), Positives = 60/129 (46%), Gaps = 18/129 (13%)

Query: 42  LKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLS----MKKVQQQ 97
           L+  +L++D L+++ K+    L    + L S    + K+  + ++E       + K+QQ+
Sbjct: 335 LQQKELQIDSLLQQEKELSSSL---HQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQK 391

Query: 98  CEK-------LEEDKKMLKEEILNLKTHMENNRVELSKLQ----EYKLELDEKAMQAVEK 146
            E+       LEE+ K   EE+  L+  ++    EL K      +  L L EK    V+ 
Sbjct: 392 EEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQS 451

Query: 147 IEEIHLQME 155
           +E++  Q E
Sbjct: 452 LEDVTAQFE 460



 Score = 29.6 bits (65), Expect = 1.5
 Identities = 32/158 (20%), Positives = 74/158 (46%), Gaps = 14/158 (8%)

Query: 19  KLLEMTIN-MLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNL 77
           K+LE  I  +L   G +D     DL+ +  KM+  +    ++   L+A    L  + + L
Sbjct: 85  KILEKEIRVLLQERGAQDRRIQ-DLETELEKMEARLNAALREKTSLSANNATLEKQLIEL 143

Query: 78  AKDNQVLQQEF------LSMKKVQQQCEKLEEDKK------MLKEEILNLKTHMENNRVE 125
            + N++L+ +F       +++ +  +  KL   ++      M K+E + +K  +    +E
Sbjct: 144 TRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLE 203

Query: 126 LSKLQEYKLELDEKAMQAVEKIEEIHLQMELDCVEQIT 163
            S+ +  +LE    +++  +  E+   +  L+ +E+I+
Sbjct: 204 ESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEIS 241


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 41/151 (27%), Positives = 70/151 (46%), Gaps = 11/151 (7%)

Query: 21  LEMTINMLNVFGNEDFDCHGDLKAD-QLKMDILIK----KLKQKFD---DLTAEKEALSS 72
           LE ++N LN   NE  +    L    + K ++L+     K  Q+ D    L   + AL  
Sbjct: 619 LETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQD 678

Query: 73  KCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEY 132
           K   L K    L Q    ++  Q+ C +LE   K  KE+ L+L+   E    ++ KL+  
Sbjct: 679 KQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEAD 738

Query: 133 KLEL---DEKAMQAVEKIEEIHLQMELDCVE 160
            LE+    E+A+Q +++  +++  +EL   E
Sbjct: 739 SLEVKASKEQALQDLQQQRQLNTDLELRATE 769



 Score = 39.7 bits (91), Expect = 0.001
 Identities = 25/117 (21%), Positives = 58/117 (49%), Gaps = 4/117 (3%)

Query: 42  LKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEF----LSMKKVQQQ 97
           L  + LK +    KL++K ++ +  K+ + +       D Q LQ        S+ ++  +
Sbjct: 307 LTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVE 366

Query: 98  CEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQM 154
             +  E  + LKEE+  ++T  ++ + E  +LQ+ + E ++  +Q   +I ++H ++
Sbjct: 367 LSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKL 423



 Score = 38.5 bits (88), Expect = 0.003
 Identities = 28/120 (23%), Positives = 58/120 (48%), Gaps = 6/120 (5%)

Query: 53  IKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQ----QEFLSMKKVQQQCEKLEEDKKML 108
           ++KLK   ++LT + + L+   +   +D   L+    +E +S K +Q    + + D + L
Sbjct: 290 LQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQL 349

Query: 109 KEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQMELDCVEQITRETKR 168
           +  +   +T +    VELS+  E   +L E+  +   K +  HL+ E   ++Q   E ++
Sbjct: 350 QSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQ--HLKAEFKQLQQQREEKEQ 407



 Score = 37.7 bits (86), Expect = 0.006
 Identities = 27/102 (26%), Positives = 59/102 (57%), Gaps = 14/102 (13%)

Query: 46  QLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDK 105
           QL  D+ ++  +     L  EKE +SS  ++L K ++ L+        ++Q+  K EE+K
Sbjct: 758 QLNTDLELRATELS-KQLEMEKEIVSSTRLDLQKKSEALES-------IKQKLTKQEEEK 809

Query: 106 KMLKE--EILNLKTHME----NNRVELSKLQEYKLELDEKAM 141
           ++LK+  E L+ +T ++    NNR++ +  +  K++++++A+
Sbjct: 810 QILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEAL 851



 Score = 37.4 bits (85), Expect = 0.007
 Identities = 26/127 (20%), Positives = 61/127 (48%), Gaps = 11/127 (8%)

Query: 40  GDLKADQLKMDILIKKLKQKFDDLTAEKEALSSKCV----------NLAKDNQVLQQEFL 89
           GD       ++ L++K K+    L  E+E L +K             L + N  LQ++  
Sbjct: 519 GDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVT 578

Query: 90  SM-KKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIE 148
            + +K++ Q E  ++ ++ L +++   K H+   +  +  L+    EL+ +  ++ EK+ 
Sbjct: 579 QLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVS 638

Query: 149 EIHLQME 155
           ++ +Q++
Sbjct: 639 QLDIQIK 645



 Score = 33.5 bits (75), Expect = 0.10
 Identities = 26/128 (20%), Positives = 57/128 (44%), Gaps = 9/128 (7%)

Query: 43  KADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEF--------LSMKKV 94
           + D  K    ++ +KQK      EK+ L      L+++ ++  +E           ++KV
Sbjct: 785 RLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKV 844

Query: 95  QQQCEKLEEDKKMLKEEILNLKTHMENNRVELSK-LQEYKLELDEKAMQAVEKIEEIHLQ 153
           + + E L  +   +K+++  +   ++N++ E  K  Q+ K  + +      E   ++ +Q
Sbjct: 845 KMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQ 904

Query: 154 MELDCVEQ 161
           ME    EQ
Sbjct: 905 MENTLKEQ 912



 Score = 32.3 bits (72), Expect = 0.23
 Identities = 28/103 (27%), Positives = 56/103 (54%), Gaps = 8/103 (7%)

Query: 43  KADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLE 102
           KA QL  +I    +K K+D+  + +EA   K   L ++   L +E   ++ ++ +  +  
Sbjct: 164 KAAQLATEIA--DIKSKYDEERSLREAAEQKVTRLTEE---LNKEATVIQDLKTELLQRP 218

Query: 103 --EDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQA 143
             ED  +LK+E++ ++T M+N  +E  +  E KL+ + K +Q+
Sbjct: 219 GIEDVAVLKKELVQVQTLMDNMTLERERESE-KLKDECKKLQS 260



 Score = 31.6 bits (70), Expect = 0.40
 Identities = 40/165 (24%), Positives = 68/165 (41%), Gaps = 27/165 (16%)

Query: 46  QLKMDILIKKLKQKFDDLT-------------AEKEAL-SSKCVNLAKDNQVLQQEFLSM 91
           QLK+  L ++LK+K  + T              E++AL  S    L +    L+Q    +
Sbjct: 459 QLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQI 518

Query: 92  KKVQQQCEKLEEDKKMLKEEILNLKTHMEN----------NRVELSKLQEYKLELDEKAM 141
               Q+ + LE   +  KE I  L+   E+              L++LQE    L E+  
Sbjct: 519 GDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVT 578

Query: 142 QAVEKIE---EIHLQMELDCVEQITRETKRIVAVLNTCSRLLTSL 183
           Q  EK++   E H Q + +  +Q+  +   + A  +    L TS+
Sbjct: 579 QLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSV 623



 Score = 31.2 bits (69), Expect = 0.52
 Identities = 25/97 (25%), Positives = 47/97 (48%)

Query: 46  QLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDK 105
           Q++M+  +K+ K+    L  EKEA     + L    + L Q   ++K+ +++ ++L+ + 
Sbjct: 902 QVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNI 961

Query: 106 KMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQ 142
             LK+     K  +E  + EL      K EL+ K  Q
Sbjct: 962 NELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQ 998


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score = 45.1 bits (105), Expect = 3e-05
 Identities = 31/120 (25%), Positives = 53/120 (44%), Gaps = 9/120 (7%)

Query: 54   KKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQE----FLSMKKVQQQCEKLEEDKKMLK 109
            KKL Q+  +     EA+++KC +L K  Q LQ E     L +++    C  L++ ++   
Sbjct: 1394 KKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFD 1453

Query: 110  EEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQMELDCVEQITRETKRI 169
            + +   K   E  + EL   Q+    L  +  +     EE      LD +E + RE K +
Sbjct: 1454 KVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEE-----SLDQLETLRRENKNL 1508



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 28/118 (23%), Positives = 57/118 (48%), Gaps = 11/118 (9%)

Query: 42   LKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQ----Q 97
            L   Q   D ++ + KQK+++  AE EA         K+++ L  E   +K V +    Q
Sbjct: 1445 LDKKQRNFDKVLSEWKQKYEETQAELEASQ-------KESRSLSTELFKVKNVYEESLDQ 1497

Query: 98   CEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQME 155
             E L  + K L++EI +L   +     ++ +L++ K +++++  +    +EE    +E
Sbjct: 1498 LETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLE 1555



 Score = 37.7 bits (86), Expect = 0.006
 Identities = 35/145 (24%), Positives = 66/145 (45%), Gaps = 34/145 (23%)

Query: 41   DLKADQLKMDILIK---KLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQ 97
            DL+A++ K++IL K   KL+Q+ DDL                    L+QE      +++ 
Sbjct: 1012 DLQAEEDKVNILTKAKTKLEQQVDDLEGS-----------------LEQEKKLRMDLERA 1054

Query: 98   CEKLEEDKKMLKEEILNLKT-------HMENNRVELSKL-------QEYKLELDEKAMQA 143
              KLE D K+ +E  ++++         +E    E+S L       Q  +++L +K  + 
Sbjct: 1055 KRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKEL 1114

Query: 144  VEKIEEIHLQMELDCVEQITRETKR 168
              +IEE+  ++E +   +   E +R
Sbjct: 1115 QARIEELGEEIEAERASRAKAEKQR 1139



 Score = 37.0 bits (84), Expect = 0.009
 Identities = 33/132 (25%), Positives = 63/132 (47%), Gaps = 22/132 (16%)

Query: 45   DQLKMDILIKKLKQKFDD-------LTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQ 97
            ++++++  IK++ ++ ++       LTA+K  L  +C  L KD   L+   L++ KV+++
Sbjct: 914  NKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLE---LTLAKVEKE 970

Query: 98   CEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQMELD 157
                E   K L EE+  L          ++KL + K  L E   Q ++      LQ E D
Sbjct: 971  KHATENKVKNLTEEMAGLDE-------TIAKLSKEKKALQETHQQTLD-----DLQAEED 1018

Query: 158  CVEQITRETKRI 169
             V  +T+   ++
Sbjct: 1019 KVNILTKAKTKL 1030



 Score = 36.6 bits (83), Expect = 0.012
 Identities = 27/115 (23%), Positives = 56/115 (48%), Gaps = 3/115 (2%)

Query: 41   DLKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEK 100
            +L+  + K++    +LK + DDL++  EA+S    NL K  + L+ +   +K  +++ ++
Sbjct: 1212 NLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQR 1271

Query: 101  LEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQME 155
            L  D   L  +   L+T       +L +      +L      + ++IEE+  Q+E
Sbjct: 1272 LIND---LTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLE 1323



 Score = 32.3 bits (72), Expect = 0.23
 Identities = 24/136 (17%), Positives = 61/136 (44%), Gaps = 3/136 (2%)

Query: 15   VKYKKLLEMTINMLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKFDDLTAEKEALSSKC 74
            ++ KK +E  +N + +  N       +   +      ++K+ +   DD    +E L  + 
Sbjct: 1615 LRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQL 1674

Query: 75   VNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKL 134
              + +   +LQ E   ++++    E+ E  +K+ ++E+L+    ++    + + L   K 
Sbjct: 1675 AIVERRANLLQAE---IEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKK 1731

Query: 135  ELDEKAMQAVEKIEEI 150
            +L+    Q   ++EE+
Sbjct: 1732 KLENDVSQLQSEVEEV 1747



 Score = 28.5 bits (62), Expect = 3.4
 Identities = 28/125 (22%), Positives = 54/125 (43%), Gaps = 16/125 (12%)

Query: 41   DLKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEK 100
            D +A ++++   IK+L+ + ++L  E EA  +      K    L +E             
Sbjct: 1099 DEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRE------------- 1145

Query: 101  LEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQ---AVEKIEEIHLQMELD 157
            LEE  + L+E        +E N+   ++ Q+ + +L+E  +Q    V  + + H     +
Sbjct: 1146 LEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAE 1205

Query: 158  CVEQI 162
              EQI
Sbjct: 1206 LGEQI 1210



 Score = 28.1 bits (61), Expect = 4.4
 Identities = 14/53 (26%), Positives = 27/53 (50%)

Query: 96   QQCEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIE 148
            Q+ E+LEE KK L + +   + H+E    + + L++ K  L  +    +  +E
Sbjct: 1384 QRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVE 1436


>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
          Length = 1684

 Score = 44.3 bits (103), Expect = 6e-05
 Identities = 34/127 (26%), Positives = 63/127 (49%), Gaps = 15/127 (11%)

Query: 52  LIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEE 111
           +IK L ++ D L  EK     +C++L K+N  ++QE      V+    K+ +  K L++ 
Sbjct: 70  IIKALTERLDALLLEKAETEQQCLSLKKENIKMKQE------VEDSVTKMGDAHKELEQS 123

Query: 112 ILNLKTHMENNRVEL----SKLQEYKLELDEKAMQAVEKIEEIHLQMEL-----DCVEQI 162
            +N    +EN + EL    SK  E K  L ++  +A+    E+  Q++      D V+++
Sbjct: 124 HINYVKEIENLKNELMAVRSKYSEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKKL 183

Query: 163 TRETKRI 169
             E ++I
Sbjct: 184 QEEIEKI 190



 Score = 39.7 bits (91), Expect = 0.001
 Identities = 35/133 (26%), Positives = 69/133 (51%), Gaps = 16/133 (12%)

Query: 56  LKQKFDDLTAEKEALSSKCVNLAKDNQVLQQE----FLSMKKVQQQCEKLE---EDKKML 108
           L+++ +++ +EKEAL S  + +   N+  + E     + +++V Q C K E   E +K  
Sbjct: 843 LRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCSKSEIHNEKEKCF 902

Query: 109 KEEILNLKTHME-----NNRVELSKLQEYKLE---LDEKAMQAVEKIEEIHLQMELDCVE 160
            +E  NLK  +E     + R EL  L++   +   +    + +V+++EE    +E +C E
Sbjct: 903 IKEHENLKPLLEQKELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKE 962

Query: 161 QITRETK-RIVAV 172
           +  +  K ++VAV
Sbjct: 963 KEEKINKIKLVAV 975



 Score = 34.7 bits (78), Expect = 0.047
 Identities = 33/115 (28%), Positives = 56/115 (48%), Gaps = 16/115 (13%)

Query: 50  DILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQE----------FLSMKK---VQQ 96
           D  ++KL  +   L+ +KE LS++  +L ++N  L  E          FLS K+   +++
Sbjct: 663 DQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVILKE 722

Query: 97  QCEKLEEDKKMLKEEILNLKTHMENNRVE--LSKLQEYKLELDEKAMQAVEKIEE 149
              +LE+  +++ EE  NL   +EN +V+    K Q Y   L E   +  E  EE
Sbjct: 723 HITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVKTQLYGF-LKEMGSEVSEDSEE 776



 Score = 30.4 bits (67), Expect = 0.89
 Identities = 31/123 (25%), Positives = 54/123 (43%), Gaps = 19/123 (15%)

Query: 41  DLKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQ-----------QEFL 89
           D + ++L +   I+ LK++ ++L  EK+       +L +  ++LQ           QEF 
Sbjct: 447 DSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNYESLREIMEILQTELGESAGKISQEFE 506

Query: 90  SMKKVQQQCEKLEEDKKML------KEEILNLKTHMENNRVELSKLQEYKLELDEKAMQA 143
           SMK  QQQ   + E ++ L      K+ +L     ++    +L   QE   EL+      
Sbjct: 507 SMK--QQQASDVHELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQELVPELENTIKNL 564

Query: 144 VEK 146
            EK
Sbjct: 565 QEK 567



 Score = 29.3 bits (64), Expect = 2.0
 Identities = 20/103 (19%), Positives = 46/103 (44%)

Query: 53  IKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEI 112
           + +L+QK      EK+AL      L  +N+ L  +   + +++   + L+E   +    +
Sbjct: 516 VHELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQELVPELENTIKNLQEKNGVYLLSL 575

Query: 113 LNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQME 155
               T ++    +++ L E K +   K   + E+++  H + E
Sbjct: 576 SQRDTMLKELEGKINSLTEEKDDFINKLKNSHEEMDNFHKKCE 618



 Score = 29.3 bits (64), Expect = 2.0
 Identities = 23/105 (21%), Positives = 49/105 (46%), Gaps = 7/105 (6%)

Query: 53  IKKLKQKFDDLTAEKEA---LSSKCVNLAKDNQV----LQQEFLSMKKVQQQCEKLEEDK 105
           + +L+ + + L +++E    L +   NL + N V    L Q    +K+++ +   L E+K
Sbjct: 537 VNRLQGENEKLLSQQELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEEK 596

Query: 106 KMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEI 150
                ++ N    M+N   +  + +   LEL +K  Q ++   E+
Sbjct: 597 DDFINKLKNSHEEMDNFHKKCEREERLILELGKKVEQTIQYNSEL 641



 Score = 26.9 bits (58), Expect = 9.8
 Identities = 23/89 (25%), Positives = 45/89 (50%), Gaps = 8/89 (8%)

Query: 73  KCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEY 132
           K + L K+ + LQ+E +       QCE+L+   +  ++E + L+  +E  + E   LQ  
Sbjct: 807 KVLELEKEIKCLQEESVV------QCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSD 860

Query: 133 KLELDEKAMQAVEKIEEIHLQMELDCVEQ 161
            LE+  K      ++E  +L ++++ V Q
Sbjct: 861 LLEM--KNANEKTRLENQNLLIQVEEVSQ 887


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 44.3 bits (103), Expect = 6e-05
 Identities = 33/134 (24%), Positives = 72/134 (53%), Gaps = 10/134 (7%)

Query: 45   DQLKMDILIKKLKQKFDDLTAEKE-------ALSSKCVNLAKDNQVLQQEFLSMKKVQQQ 97
            +Q ++ +L  +LK++ + +  EK         LS  C  LA+  + L+++   +++ QQQ
Sbjct: 1083 NQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQ 1142

Query: 98   CEKLEEDKKMLKE---EILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQM 154
               ++E+   +++   EI NLK  ++N  + L  ++  +LEL +K  +  E+++ I  + 
Sbjct: 1143 LLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKER 1202

Query: 155  ELDCVEQITRETKR 168
            ++    Q + ET+R
Sbjct: 1203 KVLKELQKSFETER 1216



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 31/111 (27%), Positives = 56/111 (50%), Gaps = 8/111 (7%)

Query: 57  KQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMK-----KVQQQCEKLEEDKKMLKEE 111
           +QK+  +  E E ++ + VNL+K+ Q       ++K     K Q+  EK  E ++ L  E
Sbjct: 830 EQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERL-NE 888

Query: 112 ILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQMELDCVEQI 162
           +  LK  +EN    L  ++  K  + EK  Q +E+++   L  E D ++Q+
Sbjct: 889 MEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKT--LTQEKDDLKQL 937



 Score = 35.0 bits (79), Expect = 0.036
 Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 35/167 (20%)

Query: 41  DLKADQLKMDILIKKLKQKFDDL---TAEKEALSSKCVNLAKDNQVL------------- 84
           +LK+   +++ L K+++ K ++L   T+EK+ L S+ V+     Q L             
Sbjct: 748 ELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLAT 807

Query: 85  --------QQEFLSMKKVQQQCEK-----LEEDKKMLKEEILNLKTHMENNRVELSKLQE 131
                    QEF + K +    E+     LEE+++M  +EI+NL    +     L  L  
Sbjct: 808 TQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERM-NQEIVNLSKEAQKFDSSLGAL-- 864

Query: 132 YKLELDEKAMQAVEKIEEIHLQMELDCVEQITRETKRIVAVLNTCSR 178
            K EL  K  +  EK  E+  Q  L+ +EQ+  + +   + L T  R
Sbjct: 865 -KTELSYKTQELQEKTREV--QERLNEMEQLKEQLENRDSTLQTVER 908



 Score = 32.0 bits (71), Expect = 0.30
 Identities = 38/132 (28%), Positives = 64/132 (48%), Gaps = 18/132 (13%)

Query: 53   IKKLKQKFDDLTAEKEALSSKCVNL----------AKDNQVLQQEFLSMKKVQQQCEKLE 102
            IK L ++ D+L   KEAL  K   L           +++Q  Q++ L+MK+   +  K+ 
Sbjct: 1344 IKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIV 1403

Query: 103  EDKKMLKEEILNLKTHMENNRVELSK-LQEYKLELDEKAMQA--VEKIEEIHLQMELDCV 159
             + +  K +   L   +E   + LSK LQE   E+   A +   +++++E+ LQ E D  
Sbjct: 1404 SEMEQFKPKDSAL-LRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEV-LQSESD-- 1459

Query: 160  EQITRETKRIVA 171
             Q+    K IVA
Sbjct: 1460 -QLKENIKEIVA 1470



 Score = 31.2 bits (69), Expect = 0.52
 Identities = 33/156 (21%), Positives = 72/156 (46%), Gaps = 12/156 (7%)

Query: 39   HGDLKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEF----LSMKKV 94
            H  LK  Q  +D L   + +K ++++  ++ L      L   +  +Q+E     + +K+ 
Sbjct: 1727 HMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQ 1786

Query: 95   QQQCEKLEEDKKMLKEEILNLKTHMENNRVEL-SKLQEYK------LELDEKAMQAVEKI 147
            Q+  +KL        +++ N++  +EN+  +L  K+QE K      + L +   +  +K+
Sbjct: 1787 QETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKV 1846

Query: 148  EEIHLQMELDCVEQITRETKRIVAVLNTCSRLLTSL 183
             E+  Q++    +Q    +K  +  LN   +L  +L
Sbjct: 1847 SEME-QLKKQIKDQSLTLSKLEIENLNLAQKLHENL 1881



 Score = 30.4 bits (67), Expect = 0.89
 Identities = 25/93 (26%), Positives = 46/93 (49%), Gaps = 6/93 (6%)

Query: 79   KDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDE 138
            KD+  L +  +   ++ ++ ++ +E+ K L +E  NLKT  E   V+  +L+E+  E   
Sbjct: 1318 KDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLA 1377

Query: 139  KAMQAVEKIEEIHLQMELDCVEQITRETKRIVA 171
            K  ++  K E+     E D       ET +IV+
Sbjct: 1378 KIQESQSKQEQSLNMKEKD------NETTKIVS 1404



 Score = 30.0 bits (66), Expect = 1.2
 Identities = 34/148 (22%), Positives = 67/148 (45%), Gaps = 27/148 (18%)

Query: 39   HGDLKADQLKMDILIKKLKQKFDDLTA---EKEALSSKCVNLAKDNQVLQQEFLSMKKVQ 95
            H  LK  +  ++ L   L +K  +++    + EA++ K  N  ++    +++F ++K++ 
Sbjct: 1483 HCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQF-NIKQIS 1541

Query: 96   QQCEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIE------- 148
            +  EK+ E K+         K H +     L  ++   LEL  +  ++ E+I+       
Sbjct: 1542 EVQEKVNELKQF--------KEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKE 1593

Query: 149  -----EIHLQMELDCVEQITRETKRIVA 171
                 +  LQ+E D   Q+   TK IVA
Sbjct: 1594 EMKRVQEALQIERD---QLKENTKEIVA 1618



 Score = 29.3 bits (64), Expect = 2.0
 Identities = 26/106 (24%), Positives = 47/106 (44%), Gaps = 4/106 (3%)

Query: 53   IKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKM----L 108
            +++LK++  D +     L  + +NLA+      +E  S+ K +    ++EE  K+    L
Sbjct: 1849 MEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQL 1908

Query: 109  KEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQM 154
            KE +   K      + EL   +    E  E   +  EKI E  +Q+
Sbjct: 1909 KESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQI 1954



 Score = 28.5 bits (62), Expect = 3.4
 Identities = 29/132 (21%), Positives = 62/132 (46%), Gaps = 7/132 (5%)

Query: 56   LKQKFDDLTAEKEALSSKC---VNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEI 112
            LKQ  + L  E++ L S     VN+  D Q  +Q   +++ ++Q  E +   K  + EE+
Sbjct: 934  LKQLQESLQIERDQLKSDIHDTVNMNIDTQ--EQLRNALESLKQHQETINTLKSKISEEV 991

Query: 113  LNLKTHMENNRVEL-SKLQEYKLELDEKAMQAVEKIEEIHLQMELDCVEQITRETKRIVA 171
             +   HME N  E   + Q+  + +D+K     +  + +   ++ + + +  R+   ++ 
Sbjct: 992  -SRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQ 1050

Query: 172  VLNTCSRLLTSL 183
              N   ++L S+
Sbjct: 1051 EKNELQQMLESV 1062



 Score = 28.1 bits (61), Expect = 4.4
 Identities = 27/130 (20%), Positives = 64/130 (49%), Gaps = 18/130 (13%)

Query: 42   LKADQLKMDI--LIKKLKQ------KFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKK 93
            ++ DQLK +   ++ K+K+      +F  +TA  E     C  +    +  + + L+++ 
Sbjct: 1604 IERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMC-EIEHLKEQFETQKLNLEN 1662

Query: 94   VQQQC--------EKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQAVE 145
            ++ +         E LEE + + KE   +L++  E  +VE  +L+E   E   + ++  E
Sbjct: 1663 IETENIRLTQILHENLEEMRSVTKERD-DLRSVEETLKVERDQLKENLRETITRDLEKQE 1721

Query: 146  KIEEIHLQME 155
            +++ +H+ ++
Sbjct: 1722 ELKIVHMHLK 1731


>gi|187761324 shootin1 isoform a [Homo sapiens]
          Length = 631

 Score = 43.9 bits (102), Expect = 8e-05
 Identities = 29/126 (23%), Positives = 65/126 (51%), Gaps = 22/126 (17%)

Query: 46  QLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDK 105
           +L  D++ +++    +D T + +  +  CV++    Q+        K+++ Q   ++E+K
Sbjct: 107 KLGPDVITEEINIDDEDSTTDTDGAAETCVSVQCQKQI--------KELRDQIVSVQEEK 158

Query: 106 KMLKEEILNLKTHMENNRVELSKLQEYKLELDEK--------------AMQAVEKIEEIH 151
           K+L  E+ NLK+ +     E++K+++ K  L+ +              +M AVE+ EE+ 
Sbjct: 159 KILAIELENLKSKLVEVIEEVNKVKQEKTVLNSEVLEQRKVLEKCNRVSMLAVEEYEEMQ 218

Query: 152 LQMELD 157
           + +EL+
Sbjct: 219 VNLELE 224



 Score = 30.8 bits (68), Expect = 0.68
 Identities = 25/110 (22%), Positives = 55/110 (50%), Gaps = 16/110 (14%)

Query: 44  ADQLKMDILIKKLKQK----FDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCE 99
           +D+ K   LI  LK++    ++DL AE +    KC      +++ Q+   ++KK+    E
Sbjct: 4   SDEEKQLQLITSLKEQAIGEYEDLRAENQKTKEKC------DKIRQERDEAVKKL----E 53

Query: 100 KLEEDKKMLKEEILNLKTHMENNRV--ELSKLQEYKLELDEKAMQAVEKI 147
           + ++   M+ EE+  ++ H+E  +   E ++    KL  + K ++ +  +
Sbjct: 54  EFQKISHMVIEEVNFMQNHLEIEKTCRESAEALATKLNKENKTLKRISML 103



 Score = 30.8 bits (68), Expect = 0.68
 Identities = 36/148 (24%), Positives = 70/148 (47%), Gaps = 19/148 (12%)

Query: 15  VKYKKLLEMT--INMLNVFGNEDFDCHGDL------KADQLKMDILIKKLKQKFDDLTAE 66
           ++ +K+LE    ++ML V   E+   + +L      KA+    ++ I++ K K       
Sbjct: 194 LEQRKVLEKCNRVSMLAVEEYEEMQVNLELEKDLRKKAESFAQEMFIEQNKLKRQSHLLL 253

Query: 67  KEALSSKCVNLAKDNQVLQQEFLSMKKVQ--QQCEKLEE--DKKMLKEEILNLKTHMENN 122
           + ++  + +  A D      + L  +++Q  Q+ ++LEE  + + L +EI NLK  +E  
Sbjct: 254 QSSIPDQQLLKALDENAKLTQQLEEERIQHQQKVKELEEQLENETLHKEIHNLKQQLE-- 311

Query: 123 RVELSKLQEYKLELDEKAMQAVEKIEEI 150
                 L+E K EL+ K   + EK   +
Sbjct: 312 -----LLEEDKKELELKYQNSEEKARNL 334



 Score = 30.4 bits (67), Expect = 0.89
 Identities = 18/52 (34%), Positives = 30/52 (57%), Gaps = 3/52 (5%)

Query: 80  DNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVELSKLQE 131
           +N+ L +E  ++K   QQ E LEEDKK L+ +  N +    N +  + +LQ+
Sbjct: 295 ENETLHKEIHNLK---QQLELLEEDKKELELKYQNSEEKARNLKHSVDELQK 343


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.131    0.359 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,965,377
Number of Sequences: 37866
Number of extensions: 244769
Number of successful extensions: 4564
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 317
Number of HSP's successfully gapped in prelim test: 527
Number of HSP's that attempted gapping in prelim test: 2241
Number of HSP's gapped (non-prelim): 2398
length of query: 183
length of database: 18,247,518
effective HSP length: 96
effective length of query: 87
effective length of database: 14,612,382
effective search space: 1271277234
effective search space used: 1271277234
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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