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Search of human proteins with 239742325
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239742325 PREDICTED: similar to coiled-coil domain
containing 29 [Homo sapiens]
(150 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239742325 PREDICTED: similar to coiled-coil domain containing... 296 6e-81
gi|169217383 PREDICTED: similar to coiled-coil domain containing... 259 8e-70
gi|169178850 PREDICTED: similar to coiled-coil domain containing... 229 5e-61
gi|239743762 PREDICTED: hypothetical protein XP_002342954 [Homo ... 195 1e-50
gi|149363632 coiled-coil domain containing 29 [Homo sapiens] 194 3e-50
gi|239750312 PREDICTED: similar to hCG1744891 [Homo sapiens] 187 3e-48
gi|239747109 PREDICTED: hypothetical protein XP_002344496 [Homo ... 176 7e-45
gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens] 160 3e-40
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 152 1e-37
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 152 1e-37
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 152 1e-37
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 146 7e-36
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 146 7e-36
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 146 7e-36
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 114 4e-26
gi|169169660 PREDICTED: hypothetical protein [Homo sapiens] 100 5e-22
gi|169169929 PREDICTED: hypothetical protein [Homo sapiens] 100 5e-22
gi|149363642 coiled-coil domain containing 144A [Homo sapiens] 77 5e-15
gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens] 44 7e-05
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 41 3e-04
gi|50083279 centrosome protein 4 [Homo sapiens] 41 3e-04
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 41 4e-04
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 41 4e-04
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 40 6e-04
gi|55770834 centromere protein F [Homo sapiens] 40 7e-04
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 40 0.001
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 40 0.001
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 39 0.001
gi|197276647 leucine rich repeat (in FLII) interacting protein 2... 39 0.001
gi|5453726 leucine rich repeat (in FLII) interacting protein 2 i... 39 0.001
>gi|239742325 PREDICTED: similar to coiled-coil domain containing 29
[Homo sapiens]
Length = 150
Score = 296 bits (757), Expect = 6e-81
Identities = 150/150 (100%), Positives = 150/150 (100%)
Query: 1 MRFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKT 60
MRFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKT
Sbjct: 1 MRFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKT 60
Query: 61 HMENSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIRETKRTAAVLDTCS 120
HMENSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIRETKRTAAVLDTCS
Sbjct: 61 HMENSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIRETKRTAAVLDTCS 120
Query: 121 HLLSSLESTGKPHLTKRIFNHNVLKKNCMI 150
HLLSSLESTGKPHLTKRIFNHNVLKKNCMI
Sbjct: 121 HLLSSLESTGKPHLTKRIFNHNVLKKNCMI 150
>gi|169217383 PREDICTED: similar to coiled-coil domain containing 29
[Homo sapiens]
Length = 185
Score = 259 bits (661), Expect = 8e-70
Identities = 129/149 (86%), Positives = 142/149 (95%)
Query: 2 RFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH 61
+FDDL EEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEE++KMLEEEILNLKTH
Sbjct: 37 KFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTH 96
Query: 62 MENSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIRETKRTAAVLDTCSH 121
MEN++VELS+LQ+YKSE DERA+QAVEKL+EI+L ME DC+EQIIRETKRT AVLDTCSH
Sbjct: 97 MENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQMEADCVEQIIRETKRTVAVLDTCSH 156
Query: 122 LLSSLESTGKPHLTKRIFNHNVLKKNCMI 150
LLSSLESTGKP+LTKRIFNH VL+KNCMI
Sbjct: 157 LLSSLESTGKPYLTKRIFNHKVLRKNCMI 185
>gi|169178850 PREDICTED: similar to coiled-coil domain containing 29
[Homo sapiens]
Length = 197
Score = 229 bits (585), Expect = 5e-61
Identities = 117/128 (91%), Positives = 124/128 (96%)
Query: 2 RFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH 61
+FDDLMAEEEAVSSKCVNL+KDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH
Sbjct: 37 KFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH 96
Query: 62 MENSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIRETKRTAAVLDTCSH 121
MENS+VELS+LQ+YKSELDERAMQAVEKLKEI+L ME DC+EQIIRETKRT AVLDTC H
Sbjct: 97 MENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQMELDCVEQIIRETKRTVAVLDTCCH 156
Query: 122 LLSSLEST 129
LLSSLEST
Sbjct: 157 LLSSLEST 164
>gi|239743762 PREDICTED: hypothetical protein XP_002342954 [Homo
sapiens]
Length = 183
Score = 195 bits (495), Expect = 1e-50
Identities = 97/125 (77%), Positives = 115/125 (92%)
Query: 2 RFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH 61
+FDDL AE+EA+SSKCVNLAKDNQV+QQE LSMKKVQQ+CEKLEE++KML+EEILNLKTH
Sbjct: 59 KFDDLTAEKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTH 118
Query: 62 MENSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIRETKRTAAVLDTCSH 121
MEN+ VELS+LQ+YK ELDE+AMQAVEK++EI+L ME DC+EQI RETKR AVL+TCS
Sbjct: 119 MENNRVELSKLQEYKLELDEKAMQAVEKIEEIHLQMELDCVEQITRETKRIVAVLNTCSR 178
Query: 122 LLSSL 126
LL+SL
Sbjct: 179 LLTSL 183
>gi|149363632 coiled-coil domain containing 29 [Homo sapiens]
Length = 161
Score = 194 bits (492), Expect = 3e-50
Identities = 96/125 (76%), Positives = 115/125 (92%)
Query: 2 RFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH 61
+FDDL A++EA+SSKCVNLAKDNQV+QQE LSMKKVQQ+CEKLEE++KML+EEILNLKTH
Sbjct: 37 KFDDLTAQKEALSSKCVNLAKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTH 96
Query: 62 MENSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIRETKRTAAVLDTCSH 121
MEN+ VE+S+LQ+YK ELDE+AMQAVEKL+EI+L ME DC+EQI RETKR AVL+TCS
Sbjct: 97 MENNRVEISKLQEYKLELDEKAMQAVEKLEEIHLQMELDCVEQITRETKRIVAVLNTCSR 156
Query: 122 LLSSL 126
LL+SL
Sbjct: 157 LLTSL 161
>gi|239750312 PREDICTED: similar to hCG1744891 [Homo sapiens]
Length = 154
Score = 187 bits (475), Expect = 3e-48
Identities = 94/111 (84%), Positives = 106/111 (95%)
Query: 2 RFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH 61
+FDDL EEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEE++KMLEEEILNLKTH
Sbjct: 37 KFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTH 96
Query: 62 MENSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIRETKRT 112
MEN++VELS+LQ+YKSE DERA+QAVEKL+EI+L ME DC+EQIIRETKR+
Sbjct: 97 MENNMVELSKLQEYKSEPDERAIQAVEKLEEIHLQMEADCVEQIIRETKRS 147
>gi|239747109 PREDICTED: hypothetical protein XP_002344496 [Homo
sapiens]
Length = 146
Score = 176 bits (446), Expect = 7e-45
Identities = 90/103 (87%), Positives = 98/103 (95%), Gaps = 2/103 (1%)
Query: 2 RFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH 61
+FDDLMAEEEAVSSKCVNL+KDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH
Sbjct: 37 KFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH 96
Query: 62 MENSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQ 104
MENS+VELS+LQ+YKSELDERAMQAVEKLKEI H++ C+ Q
Sbjct: 97 MENSMVELSKLQEYKSELDERAMQAVEKLKEI--HLQVTCLNQ 137
>gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens]
Length = 561
Score = 160 bits (406), Expect = 3e-40
Identities = 82/104 (78%), Positives = 96/104 (92%)
Query: 2 RFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH 61
+FDD MAE+EAVSSKCVNLAK+ QV QQELLSMKKVQQECEKLEE++KMLEEEILNLKTH
Sbjct: 447 QFDDFMAEKEAVSSKCVNLAKEIQVFQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTH 506
Query: 62 MENSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQI 105
MENS+VELS+LQ+YKSELDERAMQAVEKL+EI+L + + +Q+
Sbjct: 507 MENSMVELSKLQEYKSELDERAMQAVEKLEEIHLQEQAEHKKQL 550
>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1363
Score = 152 bits (384), Expect = 1e-37
Identities = 77/126 (61%), Positives = 101/126 (80%)
Query: 2 RFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH 61
+FDDLMAE+EAVSSKCVNLAKDN+V+ QELLSM KVQ++CEKLE+++KMLEE++LNLKTH
Sbjct: 857 KFDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTH 916
Query: 62 MENSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIRETKRTAAVLDTCSH 121
ME +VEL ++Q+YKSELDERAMQA+EKL+EI+L + + +Q+ + K A L
Sbjct: 917 MEKDMVELGKVQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKEL 976
Query: 122 LLSSLE 127
L +E
Sbjct: 977 TLKDVE 982
>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1366
Score = 152 bits (384), Expect = 1e-37
Identities = 77/126 (61%), Positives = 101/126 (80%)
Query: 2 RFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH 61
+FDDLMAE+EAVSSKCVNLAKDN+V+ QELLSM KVQ++CEKLE+++KMLEE++LNLKTH
Sbjct: 886 KFDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTH 945
Query: 62 MENSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIRETKRTAAVLDTCSH 121
ME +VEL ++Q+YKSELDERAMQA+EKL+EI+L + + +Q+ + K A L
Sbjct: 946 MEKDMVELGKVQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKEL 1005
Query: 122 LLSSLE 127
L +E
Sbjct: 1006 TLKDVE 1011
>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1139
Score = 152 bits (384), Expect = 1e-37
Identities = 77/126 (61%), Positives = 101/126 (80%)
Query: 2 RFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH 61
+FDDLMAE+EAVSSKCVNLAKDN+V+ QELLSM KVQ++CEKLE+++KMLEE++LNLKTH
Sbjct: 886 KFDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTH 945
Query: 62 MENSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIRETKRTAAVLDTCSH 121
ME +VEL ++Q+YKSELDERAMQA+EKL+EI+L + + +Q+ + K A L
Sbjct: 946 MEKDMVELGKVQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKEL 1005
Query: 122 LLSSLE 127
L +E
Sbjct: 1006 TLKDVE 1011
>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 146 bits (368), Expect = 7e-36
Identities = 73/126 (57%), Positives = 100/126 (79%)
Query: 2 RFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH 61
+F+DL+AE+EAVSS+CVNLAKDN+V+ QELLSM+ VQ++CEKLE+++KMLEEE+LNLKTH
Sbjct: 856 KFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTH 915
Query: 62 MENSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIRETKRTAAVLDTCSH 121
ME +VEL +LQ+YKSELDERA+Q +EKL+EI+L + + +Q+ + K A L
Sbjct: 916 MEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKEL 975
Query: 122 LLSSLE 127
L +E
Sbjct: 976 TLKDVE 981
>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1002
Score = 146 bits (368), Expect = 7e-36
Identities = 73/126 (57%), Positives = 100/126 (79%)
Query: 2 RFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH 61
+F+DL+AE+EAVSS+CVNLAKDN+V+ QELLSM+ VQ++CEKLE+++KMLEEE+LNLKTH
Sbjct: 749 KFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTH 808
Query: 62 MENSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIRETKRTAAVLDTCSH 121
ME +VEL +LQ+YKSELDERA+Q +EKL+EI+L + + +Q+ + K A L
Sbjct: 809 MEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKEL 868
Query: 122 LLSSLE 127
L +E
Sbjct: 869 TLKDVE 874
>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 146 bits (368), Expect = 7e-36
Identities = 73/126 (57%), Positives = 100/126 (79%)
Query: 2 RFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH 61
+F+DL+AE+EAVSS+CVNLAKDN+V+ QELLSM+ VQ++CEKLE+++KMLEEE+LNLKTH
Sbjct: 856 KFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTH 915
Query: 62 MENSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIRETKRTAAVLDTCSH 121
ME +VEL +LQ+YKSELDERA+Q +EKL+EI+L + + +Q+ + K A L
Sbjct: 916 MEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKEL 975
Query: 122 LLSSLE 127
L +E
Sbjct: 976 TLKDVE 981
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 114 bits (284), Expect = 4e-26
Identities = 52/104 (50%), Positives = 80/104 (76%), Gaps = 1/104 (0%)
Query: 2 RFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH 61
+ DDL AE E SKC++L NQ++Q+ELLSMK VQ++CEKL++N+K LE+E++NL++H
Sbjct: 1405 KIDDLTAELETAGSKCLHLDTKNQILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSH 1464
Query: 62 MENSIVELSELQDYKSELDERAMQAV-EKLKEINLHMEPDCIEQ 104
+E ++VEL +++ YK E++ERA Q + EKLKE+NL ++ Q
Sbjct: 1465 IERNMVELGQVKQYKQEIEERARQEIAEKLKEVNLFLQAQAASQ 1508
Score = 33.1 bits (74), Expect = 0.090
Identities = 24/104 (23%), Positives = 51/104 (49%), Gaps = 13/104 (12%)
Query: 8 AEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQEC-----------EKLEENQKMLEEEIL 56
A E S +NL + Q ++++L ++ QE EK++++++ LE++
Sbjct: 1240 ASLEVTSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNA 1299
Query: 57 NLKTHMENSIVELSELQD--YKSELDERAMQAVEKLKEINLHME 98
LK ++ + ++ ELQ + L E + ++KL E+ +E
Sbjct: 1300 KLKVTVKKQMDKIEELQKNLLNANLSEDEKEQLKKLMELKQSLE 1343
>gi|169169660 PREDICTED: hypothetical protein [Homo sapiens]
Length = 460
Score = 100 bits (249), Expect = 5e-22
Identities = 50/80 (62%), Positives = 68/80 (85%), Gaps = 1/80 (1%)
Query: 16 KCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSIVELSELQDY 75
KC+ LAK NQVIQQELLSMK+VQQ+C+KLEE K+LE+E++NLKTH E ++VE ++++
Sbjct: 335 KCLYLAKKNQVIQQELLSMKEVQQKCKKLEEVNKILEQEVVNLKTH-EKNMVEFGDVEEC 393
Query: 76 KSELDERAMQAVEKLKEINL 95
K +L+ERA Q +EKL+EINL
Sbjct: 394 KLQLEERAGQEIEKLEEINL 413
>gi|169169929 PREDICTED: hypothetical protein [Homo sapiens]
Length = 460
Score = 100 bits (249), Expect = 5e-22
Identities = 50/80 (62%), Positives = 68/80 (85%), Gaps = 1/80 (1%)
Query: 16 KCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSIVELSELQDY 75
KC+ LAK NQVIQQELLSMK+VQQ+C+KLEE K+LE+E++NLKTH E ++VE ++++
Sbjct: 335 KCLYLAKKNQVIQQELLSMKEVQQKCKKLEEVNKILEQEVVNLKTH-EKNMVEFGDVEEC 393
Query: 76 KSELDERAMQAVEKLKEINL 95
K +L+ERA Q +EKL+EINL
Sbjct: 394 KLQLEERAGQEIEKLEEINL 413
>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
Length = 1427
Score = 77.0 bits (188), Expect = 5e-15
Identities = 45/131 (34%), Positives = 82/131 (62%), Gaps = 7/131 (5%)
Query: 5 DLMAEEEAVSSKCVNLAKDNQVIQ--QELLSMKKVQQECEKLEENQKMLEEEILNLKTHM 62
DL +E V S+C++L +N+V+Q Q L SMK +Q++CE L++N+K L++E++NLK++M
Sbjct: 1126 DLTEAQETVPSRCLHLDAENEVLQLQQTLFSMKAIQKQCETLQKNKKQLKQEVVNLKSYM 1185
Query: 63 ENSIVELSELQDYKSELDERAMQAV-EKLKEINLHMEPDCI---EQIIRETKRTAAVLDT 118
E +++E + + +K ++ERA + + EKL E L ++ EQ+++ + + T
Sbjct: 1186 ERNMLERGKAEWHKLLIEERARKEIEEKLNEAILTLQKQAAVSHEQLVQLREDNTTSIKT 1245
Query: 119 CSHL-LSSLES 128
L + LES
Sbjct: 1246 QMELTIKDLES 1256
Score = 30.0 bits (66), Expect = 0.76
Identities = 23/114 (20%), Positives = 53/114 (46%), Gaps = 7/114 (6%)
Query: 25 QVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSIVELSELQDYKSELDERAM 84
Q+ Q E +KK + E +EE L+ E + L+ ++++ + + + S + ++
Sbjct: 1019 QMYQIEQSKLKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFH 1078
Query: 85 QAVEKLKEINLHMEPDCIEQIIRETKRTAAVLDTCSHLLSSLESTGKPHLTKRI 138
A + NL E + +QI+ ++ ++D +HL ++ K ++I
Sbjct: 1079 SAAK-----NLQAESE--KQILSLQEKNKELMDEYNHLKERMDQCEKEKAGRKI 1125
>gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens]
Length = 446
Score = 43.5 bits (101), Expect = 7e-05
Identities = 33/131 (25%), Positives = 63/131 (48%), Gaps = 8/131 (6%)
Query: 5 DLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMEN 64
+L E + + C++L K N +Q EL +K Q+E E L+ K LE ++ K + E
Sbjct: 151 ELCKENQELKDSCISLQKQNSDMQAEL---QKKQEELETLQSINKKLELKVKEQKDYWET 207
Query: 65 SIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIR----ETKRTAAVLDTCS 120
+++L E S +E+ V++L + L + +E++++ +T++ +
Sbjct: 208 ELLQLKEQNQKMSSENEKMGIRVDQL-QAQLSTQEKEMEKLVQGDQDKTEQLEQLKKEND 266
Query: 121 HLLSSLESTGK 131
HL SL K
Sbjct: 267 HLFLSLTEQRK 277
Score = 28.5 bits (62), Expect = 2.2
Identities = 25/114 (21%), Positives = 52/114 (45%), Gaps = 11/114 (9%)
Query: 1 MRFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQEC----EKLEENQKMLEEEIL 56
+R D L A+ + L + +Q ++L +KK + ++QK LE+ +
Sbjct: 228 IRVDQLQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVE 287
Query: 57 NLKTHMENSIVELSELQDYKSELDERAMQ------AVEKLKEINLHMEPDCIEQ 104
+K + ++ + EL D +L +R + A+++ KE L E D +++
Sbjct: 288 QMKQNETTAMKKQQELMDENFDLSKRLSENEIICNALQRQKE-RLEGENDLLKR 340
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 41.2 bits (95), Expect = 3e-04
Identities = 32/127 (25%), Positives = 54/127 (42%), Gaps = 17/127 (13%)
Query: 2 RFDDLMAEEEAVSSKCVNLAKDNQVIQQE----LLSMKKVQQECEKLEENQKMLEEEILN 57
R D EAV++KC +L K Q +Q E ++ +++ C L++ Q+ ++ +
Sbjct: 1400 RLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAE 1459
Query: 58 LKTHMENSIVELSELQDYKSELD----------ERAMQAVEKLKEINLHME---PDCIEQ 104
K E + EL Q L E ++ +E LK N +++ D EQ
Sbjct: 1460 WKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQ 1519
Query: 105 IIRETKR 111
I KR
Sbjct: 1520 IAEGGKR 1526
Score = 35.0 bits (79), Expect = 0.024
Identities = 35/138 (25%), Positives = 62/138 (44%), Gaps = 15/138 (10%)
Query: 4 DDLMAEEEAVSSKC---VNLAKDNQVIQQELLSMKKVQQECE----KLEENQKMLEEEIL 56
DDL AEE+ V++ + L + ++ L KK++ + E KLE + K+ +E +
Sbjct: 1012 DDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTM 1071
Query: 57 NLKTH-------MENSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIRET 109
+++ ++ E+S LQ + MQ +K+KE+ +E + E+I E
Sbjct: 1072 DIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIE-ELEEEIEAER 1130
Query: 110 KRTAAVLDTCSHLLSSLE 127
A S L LE
Sbjct: 1131 ASRAKAEKQRSDLSRELE 1148
Score = 34.7 bits (78), Expect = 0.031
Identities = 28/112 (25%), Positives = 55/112 (49%), Gaps = 14/112 (12%)
Query: 28 QQELLSMK----KVQQECEKLEENQKMLEEEILNLKTHMENSIVELSELQDYKSELDERA 83
++E+ +MK K ++E K E +K LEE+++ L + +++ D ++ +ER
Sbjct: 850 EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERC 909
Query: 84 MQAVE-------KLKEINLHMEPDCIEQIIRE-TKRTAAVLDTCSHLLSSLE 127
Q ++ K+KE+ E + E+I E T + + D CS L ++
Sbjct: 910 DQLIKTKIQLEAKIKEVTERAEDE--EEINAELTAKKRKLEDECSELKKDID 959
Score = 32.0 bits (71), Expect = 0.20
Identities = 31/125 (24%), Positives = 55/125 (44%), Gaps = 10/125 (8%)
Query: 5 DLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMEN 64
+L A++ + +C L KD ++ L++ KV++E E K L EE+ L +
Sbjct: 939 ELTAKKRKLEDECSELKKDIDDLE---LTLAKVEKEKHATENKVKNLTEEMAGLDETIAK 995
Query: 65 SIVELSELQD-YKSELD-----ERAMQAVEKLKEINLHMEPDCIEQIIRETKRTAAVLDT 118
E LQ+ ++ LD E + + K K I L + D +E + + K+ L+
Sbjct: 996 LTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAK-IKLEQQVDDLEGSLEQEKKIRMDLER 1054
Query: 119 CSHLL 123
L
Sbjct: 1055 AKRKL 1059
Score = 32.0 bits (71), Expect = 0.20
Identities = 23/104 (22%), Positives = 47/104 (45%), Gaps = 8/104 (7%)
Query: 3 FDDLMAEE----EAVSSKCVNLAKDNQVIQQELLSMKKVQQEC----EKLEENQKMLEEE 54
FD ++AE E ++ K+++ + EL +K +E E L+ K L++E
Sbjct: 1453 FDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQE 1512
Query: 55 ILNLKTHMENSIVELSELQDYKSELDERAMQAVEKLKEINLHME 98
I +L + + EL+ K ++++ + L+E +E
Sbjct: 1513 ISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLE 1556
>gi|50083279 centrosome protein 4 [Homo sapiens]
Length = 1140
Score = 41.2 bits (95), Expect = 3e-04
Identities = 25/92 (27%), Positives = 53/92 (57%), Gaps = 2/92 (2%)
Query: 2 RFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEK-LEENQKMLEEEILNLKT 60
R +LM +E V+S+ VNL+ N+ + QEL + ++ Q+ E+ EE + ++E+ K
Sbjct: 290 RIRELMETKETVTSEVVNLSNKNEKLCQELTEIDQLAQQLERHKEEVLETADKELGEAKK 349
Query: 61 HMENSIVELSELQDYKSELDERAMQAVEKLKE 92
++ + E+ +L++ ++L + + +K KE
Sbjct: 350 EIKRKLSEMQDLEETMAKL-QLELNLCQKEKE 380
Score = 28.9 bits (63), Expect = 1.7
Identities = 24/117 (20%), Positives = 48/117 (41%), Gaps = 2/117 (1%)
Query: 27 IQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSIVELSELQDYKSELDERAMQA 86
IQ+ + + + + + + LEEE+ + + + +LS L++ +LD
Sbjct: 932 IQEHINAHHAYESQISSMAKAMSRLEEELRHQEDEKATVLNDLSSLRELCIKLDSGKDIM 991
Query: 87 VEKLKEINLHMEPDCI--EQIIRETKRTAAVLDTCSHLLSSLESTGKPHLTKRIFNH 141
++L NL E + E + E+ L H + +LES + K +H
Sbjct: 992 TQQLNSKNLEFERVVVELENVKSESDLLKKQLSNERHTVKNLESLLATNRDKEFHSH 1048
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 40.8 bits (94), Expect = 4e-04
Identities = 26/93 (27%), Positives = 51/93 (54%), Gaps = 6/93 (6%)
Query: 11 EAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHME---NSIV 67
E + ++ +L K+N+++Q+++ ++K ++ E LE+ LE E LK ++ N
Sbjct: 628 EELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTF 687
Query: 68 ELSELQDYKSELDERAMQA---VEKLKEINLHM 97
+L L+ S+LDE ++ VE LK ++ M
Sbjct: 688 QLESLEKENSQLDEENLELRRNVESLKCASMKM 720
Score = 32.3 bits (72), Expect = 0.15
Identities = 29/113 (25%), Positives = 57/113 (50%), Gaps = 14/113 (12%)
Query: 11 EAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNL---KTHMENS-- 65
+ + S+ +L +NQ +Q+ L +K + E+LE+ K LE+E L K +E
Sbjct: 780 QQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENK 839
Query: 66 -IVELSELQDYKSELDERAMQAVEK-----LKEINLHMEPDCI--EQIIRETK 110
+ + +E++D E + + +EK KEI ++ E C+ +++ +E K
Sbjct: 840 RLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKE-SCVRLKELEKENK 891
Score = 31.2 bits (69), Expect = 0.34
Identities = 24/107 (22%), Positives = 52/107 (48%), Gaps = 9/107 (8%)
Query: 11 EAVSSKCVNLAKDNQVIQQELLSMKKVQQ-------ECEKLEENQKMLEEEILNLKTHME 63
+ S K L +N+ ++ E +KK + + E+LE + + L+ E L+ +E
Sbjct: 714 KCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLE 773
Query: 64 NSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIRETK 110
NS ++ +L+ +L+ + L+E+ + + +EQ+ +E K
Sbjct: 774 NSNKKIQQLESELQDLEMENQTLQKNLEELKISSKR--LEQLEKENK 818
Score = 30.8 bits (68), Expect = 0.45
Identities = 29/131 (22%), Positives = 61/131 (46%), Gaps = 4/131 (3%)
Query: 2 RFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH 61
R+ + + + E ++ L +DNQV+ + ++ + + LE+E L LK
Sbjct: 331 RYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAK 390
Query: 62 MENSIVELSELQDYKSELDERAM---QAVEKLKEINLHMEPDCIEQIIRETKRTAAVLDT 118
+ + +E + EL E M A ++ + +LH+ + +EQI R ++ + A +
Sbjct: 391 LHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWE-LEQISRTSELSEAPQKS 449
Query: 119 CSHLLSSLEST 129
H ++ L S+
Sbjct: 450 LGHEVNELTSS 460
Score = 28.9 bits (63), Expect = 1.7
Identities = 22/93 (23%), Positives = 47/93 (50%), Gaps = 10/93 (10%)
Query: 14 SSKCVNLAKDNQVIQQELLSMKKVQQECEK-------LEENQKMLEEEILNLKTHMENSI 66
SSK + + + I++EL K+ + E+ LE+ ++L+++I NLK E
Sbjct: 600 SSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEK-- 657
Query: 67 VELSELQDYKSELDERAM-QAVEKLKEINLHME 98
+E E ++ + E + R + + ++ K + +E
Sbjct: 658 IEALEQENSELERENRKLKKTLDSFKNLTFQLE 690
Score = 26.6 bits (57), Expect = 8.5
Identities = 26/113 (23%), Positives = 54/113 (47%), Gaps = 15/113 (13%)
Query: 25 QVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSIVELSELQDYKSELD---E 81
Q ++++ + +QE E++E K L++E +NL + + + Y+ ELD E
Sbjct: 265 QELEEKTEQLLDCKQELEQMEIELKRLQQENMNL-------LSDARSARMYRDELDALRE 317
Query: 82 RAMQAVEKLKEINLHMEP----DCIEQIIRETKR-TAAVLDTCSHLLSSLEST 129
+A++ + E++ + E + + + E K +L+T + L LE T
Sbjct: 318 KAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGT 370
Score = 26.6 bits (57), Expect = 8.5
Identities = 19/82 (23%), Positives = 38/82 (46%), Gaps = 4/82 (4%)
Query: 21 AKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSIVE----LSELQDYK 76
+K + QQ ++ K+ +CE L + + LEEE +L ++ +++ L + + K
Sbjct: 1290 SKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESK 1349
Query: 77 SELDERAMQAVEKLKEINLHME 98
Q ++KL E+ E
Sbjct: 1350 DLFHVEQRQYIDKLNELRRQKE 1371
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 40.8 bits (94), Expect = 4e-04
Identities = 26/93 (27%), Positives = 51/93 (54%), Gaps = 6/93 (6%)
Query: 11 EAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHME---NSIV 67
E + ++ +L K+N+++Q+++ ++K ++ E LE+ LE E LK ++ N
Sbjct: 628 EELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTF 687
Query: 68 ELSELQDYKSELDERAMQA---VEKLKEINLHM 97
+L L+ S+LDE ++ VE LK ++ M
Sbjct: 688 QLESLEKENSQLDEENLELRRNVESLKCASMKM 720
Score = 32.3 bits (72), Expect = 0.15
Identities = 29/113 (25%), Positives = 57/113 (50%), Gaps = 14/113 (12%)
Query: 11 EAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNL---KTHMENS-- 65
+ + S+ +L +NQ +Q+ L +K + E+LE+ K LE+E L K +E
Sbjct: 780 QQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENK 839
Query: 66 -IVELSELQDYKSELDERAMQAVEK-----LKEINLHMEPDCI--EQIIRETK 110
+ + +E++D E + + +EK KEI ++ E C+ +++ +E K
Sbjct: 840 RLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKE-SCVRLKELEKENK 891
Score = 31.2 bits (69), Expect = 0.34
Identities = 24/107 (22%), Positives = 52/107 (48%), Gaps = 9/107 (8%)
Query: 11 EAVSSKCVNLAKDNQVIQQELLSMKKVQQ-------ECEKLEENQKMLEEEILNLKTHME 63
+ S K L +N+ ++ E +KK + + E+LE + + L+ E L+ +E
Sbjct: 714 KCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLE 773
Query: 64 NSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIRETK 110
NS ++ +L+ +L+ + L+E+ + + +EQ+ +E K
Sbjct: 774 NSNKKIQQLESELQDLEMENQTLQKNLEELKISSKR--LEQLEKENK 818
Score = 30.8 bits (68), Expect = 0.45
Identities = 29/131 (22%), Positives = 61/131 (46%), Gaps = 4/131 (3%)
Query: 2 RFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH 61
R+ + + + E ++ L +DNQV+ + ++ + + LE+E L LK
Sbjct: 331 RYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAK 390
Query: 62 MENSIVELSELQDYKSELDERAM---QAVEKLKEINLHMEPDCIEQIIRETKRTAAVLDT 118
+ + +E + EL E M A ++ + +LH+ + +EQI R ++ + A +
Sbjct: 391 LHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWE-LEQISRTSELSEAPQKS 449
Query: 119 CSHLLSSLEST 129
H ++ L S+
Sbjct: 450 LGHEVNELTSS 460
Score = 28.9 bits (63), Expect = 1.7
Identities = 22/93 (23%), Positives = 47/93 (50%), Gaps = 10/93 (10%)
Query: 14 SSKCVNLAKDNQVIQQELLSMKKVQQECEK-------LEENQKMLEEEILNLKTHMENSI 66
SSK + + + I++EL K+ + E+ LE+ ++L+++I NLK E
Sbjct: 600 SSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEK-- 657
Query: 67 VELSELQDYKSELDERAM-QAVEKLKEINLHME 98
+E E ++ + E + R + + ++ K + +E
Sbjct: 658 IEALEQENSELERENRKLKKTLDSFKNLTFQLE 690
Score = 26.6 bits (57), Expect = 8.5
Identities = 26/113 (23%), Positives = 54/113 (47%), Gaps = 15/113 (13%)
Query: 25 QVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSIVELSELQDYKSELD---E 81
Q ++++ + +QE E++E K L++E +NL + + + Y+ ELD E
Sbjct: 265 QELEEKTEQLLDCKQELEQMEIELKRLQQENMNL-------LSDARSARMYRDELDALRE 317
Query: 82 RAMQAVEKLKEINLHMEP----DCIEQIIRETKR-TAAVLDTCSHLLSSLEST 129
+A++ + E++ + E + + + E K +L+T + L LE T
Sbjct: 318 KAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGT 370
Score = 26.6 bits (57), Expect = 8.5
Identities = 19/82 (23%), Positives = 38/82 (46%), Gaps = 4/82 (4%)
Query: 21 AKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSIVE----LSELQDYK 76
+K + QQ ++ K+ +CE L + + LEEE +L ++ +++ L + + K
Sbjct: 1289 SKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESK 1348
Query: 77 SELDERAMQAVEKLKEINLHME 98
Q ++KL E+ E
Sbjct: 1349 DLFHVEQRQYIDKLNELRRQKE 1370
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 40.4 bits (93), Expect = 6e-04
Identities = 40/150 (26%), Positives = 64/150 (42%), Gaps = 24/150 (16%)
Query: 2 RFDDLMAEEEAVSSKCVNLAKDNQVIQQE----LLSMKKVQQECEKLEENQKMLEEEILN 57
R D EAV+SKC +L K Q +Q E ++ +++ C L++ Q+ ++ +
Sbjct: 1400 RLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAE 1459
Query: 58 LKTHMENSIVELSELQDYKSELD----------ERAMQAVEKLKEINLHME---PDCIEQ 104
K E + EL Q L E ++ +E LK N +++ D EQ
Sbjct: 1460 WKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQ 1519
Query: 105 I------IRETKRTAAVLD-TCSHLLSSLE 127
I I E ++ LD S L +SLE
Sbjct: 1520 IAEGGKHIHELEKVKKQLDHEKSELQTSLE 1549
Score = 34.7 bits (78), Expect = 0.031
Identities = 28/112 (25%), Positives = 55/112 (49%), Gaps = 14/112 (12%)
Query: 28 QQELLSMK----KVQQECEKLEENQKMLEEEILNLKTHMENSIVELSELQDYKSELDERA 83
++E+ +MK K ++E K E +K LEE+++ L + +++ D ++ +ER
Sbjct: 850 EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERC 909
Query: 84 MQAVE-------KLKEINLHMEPDCIEQIIRE-TKRTAAVLDTCSHLLSSLE 127
Q ++ K+KE+ E + E+I E T + + D CS L ++
Sbjct: 910 DQLIKTKIQLEAKIKEVTERAEDE--EEINAELTAKKRKLEDECSELKKDID 959
Score = 34.7 bits (78), Expect = 0.031
Identities = 25/104 (24%), Positives = 46/104 (44%), Gaps = 8/104 (7%)
Query: 3 FDDLMAE----EEAVSSKCVNLAKDNQVIQQELLSMKKVQQEC----EKLEENQKMLEEE 54
FD ++AE E ++ K+++ + EL +K +E E L+ K L++E
Sbjct: 1453 FDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQE 1512
Query: 55 ILNLKTHMENSIVELSELQDYKSELDERAMQAVEKLKEINLHME 98
I +L + + EL+ K +LD + L+E +E
Sbjct: 1513 ISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLE 1556
Score = 33.9 bits (76), Expect = 0.053
Identities = 37/153 (24%), Positives = 65/153 (42%), Gaps = 15/153 (9%)
Query: 5 DLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMEN 64
+L A++ + +C L KD ++ L++ KV++E E K L EE+ L +
Sbjct: 939 ELTAKKRKLEDECSELKKDIDDLE---LTLAKVEKEKHATENKVKNLTEEMAGLDETIAK 995
Query: 65 SIVELSELQD-YKSELDERAMQ-----AVEKLKEINLHMEPDCIEQIIRETKRTAAVLDT 118
E LQ+ ++ LD+ M+ + K K L + D +E + + K+ L+
Sbjct: 996 LTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAK-TKLEQQVDDLEGSLEQEKKLCMDLER 1054
Query: 119 CSHLLS-----SLESTGKPHLTKRIFNHNVLKK 146
L + EST K+ N + KK
Sbjct: 1055 AKRKLEGDLKLAQESTMDTENDKQQLNEKLKKK 1087
Score = 31.2 bits (69), Expect = 0.34
Identities = 33/138 (23%), Positives = 57/138 (41%), Gaps = 15/138 (10%)
Query: 4 DDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEI-------- 55
DDL EE+ V++ K Q + S+++ ++ C LE ++ LE ++
Sbjct: 1012 DDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTM 1071
Query: 56 ------LNLKTHMENSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIRET 109
L ++ E+S LQ + A+Q +K+KE+ +E + E+I E
Sbjct: 1072 DTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIE-ELEEEIEAER 1130
Query: 110 KRTAAVLDTCSHLLSSLE 127
A S L LE
Sbjct: 1131 ASRAKAEKQRSDLSRELE 1148
Score = 28.9 bits (63), Expect = 1.7
Identities = 20/106 (18%), Positives = 51/106 (48%), Gaps = 17/106 (16%)
Query: 1 MRFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLK- 59
+ DD + ++ + + + + ++Q E+ ++++ E+ E +KM E+E+L+
Sbjct: 1659 LHLDDAIRGQDDLKEQLAMVERRANLMQAEV---EELRASLERTERGRKMAEQELLDASE 1715
Query: 60 ----THMENSIV---------ELSELQDYKSELDERAMQAVEKLKE 92
H +N+ + ++S++Q ++ + A A EK K+
Sbjct: 1716 RVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKK 1761
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 40.0 bits (92), Expect = 7e-04
Identities = 33/135 (24%), Positives = 63/135 (46%), Gaps = 6/135 (4%)
Query: 6 LMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENS 65
+ +E+ ++ + + L D +V+Q E L ++K + +K+ LEEE+ + +
Sbjct: 1907 IRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIV---CLEEELSVVTSERNQL 1963
Query: 66 IVELSELQDYKSELDERAMQAVEKLKEINLHMEP--DCIEQIIRETKRTAAVLDTCSHLL 123
EL + + LD+ + + EK +E+ H CI+ E K +L T S +
Sbjct: 1964 RGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDV 2023
Query: 124 SSLESTGKPHLTKRI 138
S L K HL +++
Sbjct: 2024 SEL-LKDKTHLQEKL 2037
Score = 37.0 bits (84), Expect = 0.006
Identities = 36/136 (26%), Positives = 68/136 (50%), Gaps = 11/136 (8%)
Query: 10 EEAVSSKCVNLAKDNQVIQQELLS---MKKVQQECEKLEENQKMLEEEILNLKTHME--- 63
EE +K NL NQ+ ++ + MK + + C++LEE +++L++E+ L+ E
Sbjct: 2768 EELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQK 2827
Query: 64 NSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIRE-TKRTAAVLDT-CSH 121
V +++ + +E+ E EK KE + +++ C I E ++ +L+T +H
Sbjct: 2828 TGTVMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVAH 2887
Query: 122 LL---SSLESTGKPHL 134
L S +S G P L
Sbjct: 2888 LCSQQSKQDSRGSPLL 2903
Score = 30.0 bits (66), Expect = 0.76
Identities = 23/112 (20%), Positives = 51/112 (45%), Gaps = 11/112 (9%)
Query: 5 DLMAEEEAVSSKCVNLAKDNQVI-------QQELLSMKKVQQ----ECEKLEENQKMLEE 53
+L+ ++ + K +L KD+Q + + ++ + K ++ E E L+ +
Sbjct: 2025 ELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDY 2084
Query: 54 EILNLKTHMENSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQI 105
E LN+ +E ++VE E S E Q ++++ + +E D +Q+
Sbjct: 2085 EKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQL 2136
Score = 28.9 bits (63), Expect = 1.7
Identities = 29/117 (24%), Positives = 51/117 (43%), Gaps = 9/117 (7%)
Query: 2 RFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH 61
+ + + A+E + + +A+ +Q+EL K +L ++L EEI + K
Sbjct: 2610 KVNKMTAKETELQREMHEMAQKTAELQEELSGEKN------RLAGELQLLLEEIKSSKDQ 2663
Query: 62 MENSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIRETKRTAAVLDT 118
++ +E SEL K LD VEK ++ + + E K A +LDT
Sbjct: 2664 LKELTLENSEL---KKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDT 2717
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 39.7 bits (91), Expect = 0.001
Identities = 34/123 (27%), Positives = 55/123 (44%), Gaps = 19/123 (15%)
Query: 8 AEE--EAVSSKCVNLAKDNQVIQQE----LLSMKKVQQECEKLEENQKMLEEEILNLKTH 61
AEE EAV++KC +L K Q +Q E +L +++ C L++ Q+ ++ + K
Sbjct: 1406 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQK 1465
Query: 62 MENSIVELSELQDYKSELD----------ERAMQAVEKLKEINLHME---PDCIEQIIRE 108
E + EL Q L E ++ +E LK N +++ D EQI
Sbjct: 1466 CEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG 1525
Query: 109 TKR 111
KR
Sbjct: 1526 GKR 1528
Score = 35.8 bits (81), Expect = 0.014
Identities = 35/138 (25%), Positives = 63/138 (45%), Gaps = 15/138 (10%)
Query: 4 DDLMAEEEAVSSKC---VNLAKDNQVIQQELLSMKKVQQECE----KLEENQKMLEEEIL 56
DDL AEE+ V++ + L + ++ L KK++ + E KLE + K+ +E I+
Sbjct: 1014 DDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIM 1073
Query: 57 NLKTH-------MENSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIRET 109
+++ ++ E+S LQ + +Q +K+KE+ +E + E+I E
Sbjct: 1074 DIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIE-ELEEEIEAER 1132
Query: 110 KRTAAVLDTCSHLLSSLE 127
A S L LE
Sbjct: 1133 ASRAKAEKQRSDLSRELE 1150
Score = 32.3 bits (72), Expect = 0.15
Identities = 27/112 (24%), Positives = 55/112 (49%), Gaps = 14/112 (12%)
Query: 28 QQELLSMK----KVQQECEKLEENQKMLEEEILNLKTHMENSIVELSELQDYKSELDERA 83
++E+ +MK K++ E K E +K LEE+++ L + +++ + ++ +ER
Sbjct: 852 EKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERC 911
Query: 84 MQAVE-------KLKEINLHMEPDCIEQIIRE-TKRTAAVLDTCSHLLSSLE 127
Q ++ K+KE+ E + E+I E T + + D CS L ++
Sbjct: 912 DQLIKTKIQLEAKIKEVTERAEDE--EEINAELTAKKRKLEDECSELKKDID 961
Score = 32.0 bits (71), Expect = 0.20
Identities = 31/125 (24%), Positives = 55/125 (44%), Gaps = 10/125 (8%)
Query: 5 DLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMEN 64
+L A++ + +C L KD ++ L++ KV++E E K L EE+ L +
Sbjct: 941 ELTAKKRKLEDECSELKKDIDDLE---LTLAKVEKEKHATENKVKNLTEEMAGLDETIAK 997
Query: 65 SIVELSELQD-YKSELD-----ERAMQAVEKLKEINLHMEPDCIEQIIRETKRTAAVLDT 118
E LQ+ ++ LD E + + K K I L + D +E + + K+ L+
Sbjct: 998 LTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAK-IKLEQQVDDLEGSLEQEKKLRMDLER 1056
Query: 119 CSHLL 123
L
Sbjct: 1057 AKRKL 1061
Score = 30.0 bits (66), Expect = 0.76
Identities = 23/104 (22%), Positives = 46/104 (44%), Gaps = 8/104 (7%)
Query: 3 FDDLMAEE----EAVSSKCVNLAKDNQVIQQELLSMKKVQQEC----EKLEENQKMLEEE 54
FD ++AE E ++ K+ + + EL +K +E E L+ K L++E
Sbjct: 1455 FDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQE 1514
Query: 55 ILNLKTHMENSIVELSELQDYKSELDERAMQAVEKLKEINLHME 98
I +L + + EL+ K ++++ + L+E +E
Sbjct: 1515 ISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLE 1558
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 39.7 bits (91), Expect = 0.001
Identities = 34/123 (27%), Positives = 55/123 (44%), Gaps = 19/123 (15%)
Query: 8 AEE--EAVSSKCVNLAKDNQVIQQE----LLSMKKVQQECEKLEENQKMLEEEILNLKTH 61
AEE EAV++KC +L K Q +Q E +L +++ C L++ Q+ ++ + K
Sbjct: 1406 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQK 1465
Query: 62 MENSIVELSELQDYKSELD----------ERAMQAVEKLKEINLHME---PDCIEQIIRE 108
E + EL Q L E ++ +E LK N +++ D EQI
Sbjct: 1466 CEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG 1525
Query: 109 TKR 111
KR
Sbjct: 1526 GKR 1528
Score = 35.8 bits (81), Expect = 0.014
Identities = 35/138 (25%), Positives = 63/138 (45%), Gaps = 15/138 (10%)
Query: 4 DDLMAEEEAVSSKC---VNLAKDNQVIQQELLSMKKVQQECE----KLEENQKMLEEEIL 56
DDL AEE+ V++ + L + ++ L KK++ + E KLE + K+ +E I+
Sbjct: 1014 DDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIM 1073
Query: 57 NLKTH-------MENSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIRET 109
+++ ++ E+S LQ + +Q +K+KE+ +E + E+I E
Sbjct: 1074 DIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIE-ELEEEIEAER 1132
Query: 110 KRTAAVLDTCSHLLSSLE 127
A S L LE
Sbjct: 1133 ASRAKAEKQRSDLSRELE 1150
Score = 32.3 bits (72), Expect = 0.15
Identities = 27/112 (24%), Positives = 55/112 (49%), Gaps = 14/112 (12%)
Query: 28 QQELLSMK----KVQQECEKLEENQKMLEEEILNLKTHMENSIVELSELQDYKSELDERA 83
++E+ +MK K++ E K E +K LEE+++ L + +++ + ++ +ER
Sbjct: 852 EKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERC 911
Query: 84 MQAVE-------KLKEINLHMEPDCIEQIIRE-TKRTAAVLDTCSHLLSSLE 127
Q ++ K+KE+ E + E+I E T + + D CS L ++
Sbjct: 912 DQLIKTKIQLEAKIKEVTERAEDE--EEINAELTAKKRKLEDECSELKKDID 961
Score = 32.0 bits (71), Expect = 0.20
Identities = 31/125 (24%), Positives = 55/125 (44%), Gaps = 10/125 (8%)
Query: 5 DLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMEN 64
+L A++ + +C L KD ++ L++ KV++E E K L EE+ L +
Sbjct: 941 ELTAKKRKLEDECSELKKDIDDLE---LTLAKVEKEKHATENKVKNLTEEMAGLDETIAK 997
Query: 65 SIVELSELQD-YKSELD-----ERAMQAVEKLKEINLHMEPDCIEQIIRETKRTAAVLDT 118
E LQ+ ++ LD E + + K K I L + D +E + + K+ L+
Sbjct: 998 LTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAK-IKLEQQVDDLEGSLEQEKKLRMDLER 1056
Query: 119 CSHLL 123
L
Sbjct: 1057 AKRKL 1061
Score = 30.0 bits (66), Expect = 0.76
Identities = 23/104 (22%), Positives = 46/104 (44%), Gaps = 8/104 (7%)
Query: 3 FDDLMAEE----EAVSSKCVNLAKDNQVIQQELLSMKKVQQEC----EKLEENQKMLEEE 54
FD ++AE E ++ K+ + + EL +K +E E L+ K L++E
Sbjct: 1455 FDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQE 1514
Query: 55 ILNLKTHMENSIVELSELQDYKSELDERAMQAVEKLKEINLHME 98
I +L + + EL+ K ++++ + L+E +E
Sbjct: 1515 ISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLE 1558
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 39.3 bits (90), Expect = 0.001
Identities = 37/145 (25%), Positives = 68/145 (46%), Gaps = 18/145 (12%)
Query: 2 RFDDLMAEEEAVSSKCVNLAKDNQVIQQELL-SMKKVQQECEKLEENQKMLEEEILNLKT 60
R D L+ E+ +C++L K+N ++QE+ S+ K+ ++LE++ +EI NLK
Sbjct: 77 RLDALLLEKAETEQQCLSLKKENIKMKQEVEDSVTKMGDAHKELEQSHINYVKEIENLKN 136
Query: 61 HM-----------ENSIVELSELQDYKSELDER------AMQAVEKLKEINLHMEPDCIE 103
+ N +L E + + EL E+ + V+KL+E + P E
Sbjct: 137 ELMAVRSKYSEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEE 196
Query: 104 QIIRETKRTAAVLDTCSHLLSSLES 128
QI+ K+ A D ++ L++
Sbjct: 197 QILYLQKQLDATTDEKKETVTQLQN 221
Score = 38.1 bits (87), Expect = 0.003
Identities = 33/145 (22%), Positives = 61/145 (42%), Gaps = 2/145 (1%)
Query: 4 DDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHME 63
++LMA S NL K + L + + + E+N K L+EEI ++ E
Sbjct: 136 NELMAVRSKYSEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIRPGFE 195
Query: 64 NSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIRETKRTAAV-LDTCSHL 122
I+ L + D ++ + + ++ + E N I + E + A+ + L
Sbjct: 196 EQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEEVKEL 255
Query: 123 LSSLESTGKPHLTKRIFNHNVLKKN 147
+ +E++ K H I N LK+N
Sbjct: 256 MCQIEASAKEH-EAEINKLNELKEN 279
Score = 32.0 bits (71), Expect = 0.20
Identities = 31/110 (28%), Positives = 50/110 (45%), Gaps = 18/110 (16%)
Query: 19 NLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSIVEL--------- 69
+LAK V L S+K+++++ E LE+ K EE+I +K + EL
Sbjct: 931 SLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQT 990
Query: 70 --SELQDYKSELDERA------MQAVEKLKEINLHMEPDCIEQIIRETKR 111
EL+ +SE D+ + +Q E K + L E EQ+ E +R
Sbjct: 991 VKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQS-EQLDVEKER 1039
>gi|197276647 leucine rich repeat (in FLII) interacting protein 2
isoform 3 [Homo sapiens]
Length = 424
Score = 39.3 bits (90), Expect = 0.001
Identities = 23/92 (25%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Query: 5 DLMAEEEAVSSKCVNLAKD-NQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHME 63
DL + + + + +D N+ I + + K +Q+ LE++ LE ++L KT E
Sbjct: 310 DLAGLQNGSDLQFIEMQRDANRQISEYKFKLSKAEQDITTLEQSISRLEGQVLRYKTAAE 369
Query: 64 NSIVELSELQDYKSELDERAMQAVEKLKEINL 95
N+ EL+ K +L A++K++E+ +
Sbjct: 370 NAEKVEDELKAEKRKLQRELRTALDKIEEMEM 401
>gi|5453726 leucine rich repeat (in FLII) interacting protein 2
isoform 1 [Homo sapiens]
Length = 721
Score = 39.3 bits (90), Expect = 0.001
Identities = 23/92 (25%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Query: 5 DLMAEEEAVSSKCVNLAKD-NQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHME 63
DL + + + + +D N+ I + + K +Q+ LE++ LE ++L KT E
Sbjct: 607 DLAGLQNGSDLQFIEMQRDANRQISEYKFKLSKAEQDITTLEQSISRLEGQVLRYKTAAE 666
Query: 64 NSIVELSELQDYKSELDERAMQAVEKLKEINL 95
N+ EL+ K +L A++K++E+ +
Sbjct: 667 NAEKVEDELKAEKRKLQRELRTALDKIEEMEM 698
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.127 0.339
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,996,278
Number of Sequences: 37866
Number of extensions: 197494
Number of successful extensions: 3242
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 274
Number of HSP's successfully gapped in prelim test: 369
Number of HSP's that attempted gapping in prelim test: 1730
Number of HSP's gapped (non-prelim): 1749
length of query: 150
length of database: 18,247,518
effective HSP length: 93
effective length of query: 57
effective length of database: 14,725,980
effective search space: 839380860
effective search space used: 839380860
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.