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Search of human proteins with 239742014
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239742014 PREDICTED: hypothetical protein XP_002342372 [Homo
sapiens]
(282 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239753547 PREDICTED: similar to 1700112C13Rik protein [Homo s... 592 e-170
gi|239742014 PREDICTED: hypothetical protein XP_002342372 [Homo ... 592 e-170
gi|58218970 protease, serine, 36 [Homo sapiens] 142 3e-34
gi|34098976 marapsin 2 [Homo sapiens] 142 4e-34
gi|148806900 epidermis-specific serine protease-like protein [Ho... 140 2e-33
gi|13994276 marapsin [Homo sapiens] 139 3e-33
gi|21614533 testisin isoform 3 [Homo sapiens] 135 5e-32
gi|205360905 testis-specific serine protease 1 [Homo sapiens] 134 9e-32
gi|117956391 protease, serine, 33 [Homo sapiens] 134 1e-31
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 132 3e-31
gi|116256363 transmembrane protease, serine 13 [Homo sapiens] 130 2e-30
gi|5803197 testisin isoform 1 [Homo sapiens] 129 2e-30
gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens] 129 3e-30
gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo ... 129 3e-30
gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo ... 129 3e-30
gi|4506153 prostasin preproprotein [Homo sapiens] 128 5e-30
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens] 126 2e-29
gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens] 126 2e-29
gi|4503627 coagulation factor XI precursor [Homo sapiens] 126 2e-29
gi|11545839 protease, serine, 22 [Homo sapiens] 126 2e-29
gi|33186882 testis serine protease 2 [Homo sapiens] 125 4e-29
gi|21614531 testisin isoform 2 [Homo sapiens] 125 4e-29
gi|110578663 hypothetical protein LOC203074 [Homo sapiens] 124 9e-29
gi|68508970 tryptase beta 2 precursor [Homo sapiens] 124 1e-28
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 123 2e-28
gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa... 122 3e-28
gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sap... 122 3e-28
gi|7019563 testes-specific protease 50 [Homo sapiens] 122 4e-28
gi|222831592 transmembrane protease, serine 7 [Homo sapiens] 119 3e-27
gi|148231605 ovochymase 2 [Homo sapiens] 118 7e-27
>gi|239753547 PREDICTED: similar to 1700112C13Rik protein [Homo
sapiens]
Length = 282
Score = 592 bits (1527), Expect = e-170
Identities = 282/282 (100%), Positives = 282/282 (100%)
Query: 1 MACGPGDLQSLTSPLSSARLDYQPSIEGPWLRACGQTNVSCRVVKGKLVEVGKWPWQVSI 60
MACGPGDLQSLTSPLSSARLDYQPSIEGPWLRACGQTNVSCRVVKGKLVEVGKWPWQVSI
Sbjct: 1 MACGPGDLQSLTSPLSSARLDYQPSIEGPWLRACGQTNVSCRVVKGKLVEVGKWPWQVSI 60
Query: 61 LFLGTYICSGSLIHHQWVLTAAHCLQRFKDLSLYSVMVGVHQRPENSTQLPLTRMVIHKD 120
LFLGTYICSGSLIHHQWVLTAAHCLQRFKDLSLYSVMVGVHQRPENSTQLPLTRMVIHKD
Sbjct: 61 LFLGTYICSGSLIHHQWVLTAAHCLQRFKDLSLYSVMVGVHQRPENSTQLPLTRMVIHKD 120
Query: 121 FSNLMSQDIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHPD 180
FSNLMSQDIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHPD
Sbjct: 121 FSNLMSQDIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHPD 180
Query: 181 SVKSCCEFIRECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHF 240
SVKSCCEFIRECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHF
Sbjct: 181 SVKSCCEFIRECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHF 240
Query: 241 NQWIRTEVANIRFISRAGPAFLSPVFLTGYILLGSLSSLWLL 282
NQWIRTEVANIRFISRAGPAFLSPVFLTGYILLGSLSSLWLL
Sbjct: 241 NQWIRTEVANIRFISRAGPAFLSPVFLTGYILLGSLSSLWLL 282
>gi|239742014 PREDICTED: hypothetical protein XP_002342372 [Homo
sapiens]
Length = 282
Score = 592 bits (1527), Expect = e-170
Identities = 282/282 (100%), Positives = 282/282 (100%)
Query: 1 MACGPGDLQSLTSPLSSARLDYQPSIEGPWLRACGQTNVSCRVVKGKLVEVGKWPWQVSI 60
MACGPGDLQSLTSPLSSARLDYQPSIEGPWLRACGQTNVSCRVVKGKLVEVGKWPWQVSI
Sbjct: 1 MACGPGDLQSLTSPLSSARLDYQPSIEGPWLRACGQTNVSCRVVKGKLVEVGKWPWQVSI 60
Query: 61 LFLGTYICSGSLIHHQWVLTAAHCLQRFKDLSLYSVMVGVHQRPENSTQLPLTRMVIHKD 120
LFLGTYICSGSLIHHQWVLTAAHCLQRFKDLSLYSVMVGVHQRPENSTQLPLTRMVIHKD
Sbjct: 61 LFLGTYICSGSLIHHQWVLTAAHCLQRFKDLSLYSVMVGVHQRPENSTQLPLTRMVIHKD 120
Query: 121 FSNLMSQDIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHPD 180
FSNLMSQDIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHPD
Sbjct: 121 FSNLMSQDIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHPD 180
Query: 181 SVKSCCEFIRECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHF 240
SVKSCCEFIRECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHF
Sbjct: 181 SVKSCCEFIRECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHF 240
Query: 241 NQWIRTEVANIRFISRAGPAFLSPVFLTGYILLGSLSSLWLL 282
NQWIRTEVANIRFISRAGPAFLSPVFLTGYILLGSLSSLWLL
Sbjct: 241 NQWIRTEVANIRFISRAGPAFLSPVFLTGYILLGSLSSLWLL 282
>gi|58218970 protease, serine, 36 [Homo sapiens]
Length = 855
Score = 142 bits (359), Expect = 3e-34
Identities = 93/289 (32%), Positives = 134/289 (46%), Gaps = 44/289 (15%)
Query: 13 SPLSSARLD--YQPSIEGPWLRACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSG 70
SP+ A D P+ E P CG+ S R+V G + G WPWQVS+ G +IC G
Sbjct: 15 SPIPGAFQDSALSPTQEEPEDLDCGRPEPSARIVGGSNAQPGTWPWQVSLHHGGGHICGG 74
Query: 71 SLIHHQWVLTAAHCLQ---RFKDLSLYSVMVGVHQRP---ENSTQLPLTRMVIHKDFSNL 124
SLI WVL+AAHC + + +SV++GVH + + + + +V+ ++S +
Sbjct: 75 SLIAPSWVLSAAHCFMTNGTLEPAAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPANYSQV 134
Query: 125 -MSQDIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHP---- 179
+ D+ALL+L S P V PVCLP + G+ CW GWG + L P
Sbjct: 135 ELGADLALLRLASPASLGPAVWPVCLPRASHRFVHGTACWATGWGDVQEADPLPLPWVLQ 194
Query: 180 --------DSVKSCCEFIRECFQFTLTV-------------------DSGSSLVCQMDKT 212
++ C F TL + DSG LVC+
Sbjct: 195 EVELRLLGEATCQCLYSQPGPFNLTLQILPGMLCAGYPEGRRDTCQGDSGGPLVCEEGGR 254
Query: 213 WIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWIRTEVANIRFISRAGPAF 261
W Q G+ S+ F CG+R+ PG++T+ A + WIR +V S GPAF
Sbjct: 255 WFQAGITSFGFGCGRRNRPGVFTAVATYEAWIREQVMG----SEPGPAF 299
Score = 69.7 bits (169), Expect = 3e-12
Identities = 41/130 (31%), Positives = 64/130 (49%), Gaps = 12/130 (9%)
Query: 46 GKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCL-------QRFKDLSLYSVMV 98
GK G WPW+ ++ G+ C G+L+ WVL A C +DL + V++
Sbjct: 326 GKAPRPGAWPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRVLL 385
Query: 99 GVHQRPENSTQLPLTRMVIHKDFSNLMSQDIALLKLRDSISWSPFVQPVCLPNIKFKPSI 158
R E + R+V H++ S + D+ALL+LR ++ S +PVCLP+ +
Sbjct: 386 PSRPRAER-----VARLVQHENASWDNASDLALLQLRTPVNLSAASRPVCLPHPEHYFLP 440
Query: 159 GSMCWVIGWG 168
GS C + WG
Sbjct: 441 GSRCRLARWG 450
Score = 60.8 bits (146), Expect = 1e-09
Identities = 58/240 (24%), Positives = 93/240 (38%), Gaps = 40/240 (16%)
Query: 54 WPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQR-----FKDLSLYSVMVGVHQRPENST 108
WPW + G +C+G L+ WVL A HC+ R + +Y G P+
Sbjct: 601 WPWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLPQGH- 659
Query: 109 QLPLTRMVIHKDFSNLMS--QDIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIG 166
++R+VI + +ALL+L + SP P+CL P G+ CWV+G
Sbjct: 660 --QVSRLVISIRLPQHLGLRPPLALLELSSRVEPSPSALPICLHPAGIPP--GASCWVLG 715
Query: 167 WGTTGKKGFLNHPDSV----------------KSCCEFIRECFQFTLTVDSGSSLVCQM- 209
W + + S+ + C E + + S L+CQM
Sbjct: 716 WKEPQDRVPVAAAVSILTQRICDCLYQGILPPGTLCVLYAEGQENRCEMTSAPPLLCQMT 775
Query: 210 DKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWIRTEVANIRFISRAGPAFLSPVFLTG 269
+ +WI +G+ G R ++ + WI V F+ +G SP + TG
Sbjct: 776 EGSWILVGMAVQ----GSRE---LFAAIGPEEAWISQTVGEANFLPPSG----SPHWPTG 824
>gi|34098976 marapsin 2 [Homo sapiens]
Length = 326
Score = 142 bits (357), Expect = 4e-34
Identities = 91/300 (30%), Positives = 153/300 (51%), Gaps = 37/300 (12%)
Query: 14 PLSSARLDYQPSIEGPWLR---ACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSG 70
P +A + QP +G L ACG+ ++ +++ G KWPWQVS+ + G ++C G
Sbjct: 28 PRVAALVHRQPENQGISLTGSVACGRPSMEGKILGGVPAPERKWPWQVSVHYAGLHVCGG 87
Query: 71 SLIHHQWVLTAAHCLQRFKDLSLYSVMVG-VHQR-PENSTQ-LPLTRMVIHKDFS--NLM 125
S+++ WVL+AAHC R K++ +Y + VG V+ R N TQ + R+++H + + +
Sbjct: 88 SILNEYWVLSAAHCFHRDKNIKIYDMYVGLVNLRVAGNHTQWYEVNRVILHPTYEMYHPI 147
Query: 126 SQDIALLKLRDSISWSPFVQPVCL--PNIKFKPSIGSMCWVIGWGTTGKKG-------FL 176
D+AL++L+ I +S V PVCL P + + CW GWG K+G +
Sbjct: 148 GGDVALVQLKTRIVFSESVLPVCLATPEVNL---TSANCWATGWGLVSKQGETSDELQEM 204
Query: 177 NHPDSVKSCCEFIRECFQFTL-------------TV---DSGSSLVCQMDKTWIQIGVVS 220
P ++ C + + + TV DSG LVC+ +++W+QIG+VS
Sbjct: 205 QLPLILEPWCHLLYGHMSYIMPDMLCAGDILNAKTVCEGDSGGPLVCEFNRSWLQIGIVS 264
Query: 221 WSFSCGQRHFPGIYTSTAHFNQWIRTEVANIRFISRAGPAFLSPVFLTGYILLGSLSSLW 280
W C +PG+Y S ++F++WI + ++ PA LSP +L ++ + W
Sbjct: 265 WGRGCSNPLYPGVYASVSYFSKWICDNIEITPTPAQPAPA-LSPALGPTLSVLMAMLAGW 323
>gi|148806900 epidermis-specific serine protease-like protein [Homo
sapiens]
Length = 328
Score = 140 bits (352), Expect = 2e-33
Identities = 85/278 (30%), Positives = 138/278 (49%), Gaps = 39/278 (14%)
Query: 31 LRACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQRFKD 90
+ CGQ S RVV G+ G+WPWQVS+ F +IC GSL+ + +LTAAHC+Q
Sbjct: 16 ISVCGQPVYSSRVVGGQDAAAGRWPWQVSLHFDHNFICGGSLVSERLILTAAHCIQPTWT 75
Query: 91 LSLYSVMVGVHQRPENSTQLP--LTRMVIHKDFSNLMSQDIALLKLRDSISWSPFVQPVC 148
Y+V +G ++ ++ ++++VIH + + + D+ALLKL ++++ + P+C
Sbjct: 76 TFSYTVWLGSITVGDSRKRVKYYVSKIVIHPKYQD-TTADVALLKLSSQVTFTSAILPIC 134
Query: 149 LPNIKFKPSIGSMCWVIGWGTTGKKGFLNHPDSV---------KSCCE------------ 187
LP++ + +I CWV GWG + ++ ++ + CE
Sbjct: 135 LPSVTKQLAIPPFCWVTGWGKVKESSDRDYHSALQEAEVPIIDRQACEQLYNPIGIFLPA 194
Query: 188 ---FIRE---CFQFTLTV------DSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYT 235
I+E C T + DSG L C +D WIQ GVVSW CG + PG+YT
Sbjct: 195 LEPVIKEDKICAGDTQNMKDSCKGDSGGPLSCHIDGVWIQTGVVSWGLECG-KSLPGVYT 253
Query: 236 STAHFNQWIRTEVANIRFISRAGPAFLSPVFLTGYILL 273
+ ++ +WI ++ + + FL P+ L LL
Sbjct: 254 NVIYYQKWINATISRANNLDFSD--FLFPIVLLSLALL 289
>gi|13994276 marapsin [Homo sapiens]
Length = 290
Score = 139 bits (350), Expect = 3e-33
Identities = 80/257 (31%), Positives = 120/257 (46%), Gaps = 36/257 (14%)
Query: 33 ACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQRFKDLS 92
ACG+ + R+V G+ + G+WPWQVSI G++ C GSLI QWVLTAAHC + + S
Sbjct: 25 ACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETS 84
Query: 93 LYSVMVGVHQ--RPENSTQLPLTRMVIHKDF--SNLMSQDIALLKLRDSISWSPFVQPVC 148
LY V++G Q +P R V S D+AL++L + ++ ++ PVC
Sbjct: 85 LYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPVC 144
Query: 149 LPNIKFKPSIGSMCWVIGWGTTGKKGFLNHP-----------DSVK-------------- 183
LP+ G CWV GWG+ ++ L P D+ K
Sbjct: 145 LPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQ 204
Query: 184 -------SCCEFIRECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTS 236
C E + DSG LVC + ++W+Q GV+SW C +++ PG+Y
Sbjct: 205 PKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYIR 264
Query: 237 TAHFNQWIRTEVANIRF 253
+ WI + ++F
Sbjct: 265 VTAHHNWIHRIIPKLQF 281
>gi|21614533 testisin isoform 3 [Homo sapiens]
Length = 300
Score = 135 bits (339), Expect = 5e-32
Identities = 73/240 (30%), Positives = 120/240 (50%), Gaps = 24/240 (10%)
Query: 34 CGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQRFKDLS- 92
CG+ ++ R+V G+ E+G+WPWQ S+ +++C SL+ H+W LTAAHC + + DLS
Sbjct: 33 CGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSD 92
Query: 93 ---------LYSVMVGVHQRPENSTQLPLTRMVIHKDFSNLMSQDIALLKLRDSISWSPF 143
+ M T+ ++ + + + DIAL+KL ++++
Sbjct: 93 PSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKH 152
Query: 144 VQPVCLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHPDSVK---------SCCEFIRECFQ 194
+QP+CL F+ + CWV GWG + L P +++ S C + +
Sbjct: 153 IQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYS 212
Query: 195 FTLTV-----DSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWIRTEVA 249
F + DSG L C + W QIGVVSW CG+ + PG+YT+ +H +WI+ +A
Sbjct: 213 FRKDIFGDMGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLMA 272
>gi|205360905 testis-specific serine protease 1 [Homo sapiens]
Length = 318
Score = 134 bits (337), Expect = 9e-32
Identities = 84/277 (30%), Positives = 130/277 (46%), Gaps = 40/277 (14%)
Query: 5 PGDLQSLTSPLSSARLDYQPSIEGPWLRACGQTNVSCRVVKGKLVEVGKWPWQVSILFLG 64
PG+L +L + +AR +P G ACG + V G G+WPWQ S+
Sbjct: 21 PGELGALQAGPGAAR---RPG-GGGREEACGHREIHALVAGGVESARGRWPWQASLRLRR 76
Query: 65 TYICSGSLIHHQWVLTAAHCLQRFKDLSLYSVMVG-VHQRP------ENSTQLPLTRMVI 117
+ C GSL+ +WVL+AAHC Q+ S ++V +G + RP S++ + +++
Sbjct: 77 RHRCGGSLLSRRWVLSAAHCFQKHYYPSEWTVQLGELTSRPTPWNLRAYSSRYKVQDIIV 136
Query: 118 HKDFSNLMSQDIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKG--- 174
+ D ++ DIALL+L S++++ ++QP+C+ + F CWV GWG G
Sbjct: 137 NPDALGVLRNDIALLRLASSVTYNAYIQPICIESSTFNFVHRPDCWVTGWGLISPSGTPL 196
Query: 175 --------------------FLNHPDSVKSC------CEFIRECFQFTLTVDSGSSLVCQ 208
+L S +S C + T DSG LVC
Sbjct: 197 PPPYNLREAQVTILNNTRCNYLFEQPSSRSMIWDSMFCAGAEDGSVDTCKGDSGGPLVCD 256
Query: 209 MDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWIR 245
D W Q+G+VSW CGQ + PG+YT+ + + WIR
Sbjct: 257 KDGLWYQVGIVSWGMDCGQPNRPGVYTNISVYFHWIR 293
>gi|117956391 protease, serine, 33 [Homo sapiens]
Length = 280
Score = 134 bits (336), Expect = 1e-31
Identities = 87/254 (34%), Positives = 125/254 (49%), Gaps = 38/254 (14%)
Query: 33 ACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQRFKDLS 92
ACGQ +S R+V G+ G+WPWQ SI G ++C GSLI QWVLTAAHC R +
Sbjct: 27 ACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRALPA 86
Query: 93 LYSVMVGVHQRPENSTQ---LPLTRMVIHKDFSNLMSQ-DIALLKLRDSISWSPFVQPVC 148
Y V +G + S + +P+ R+++ D+S ++ D+ALL+LR + S VQPVC
Sbjct: 87 EYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARVQPVC 146
Query: 149 LPNIKFKPSIGSMCWVIGWGTTGKKGF-----------------------LNH-----PD 180
LP +P G+ C V GWG+ + G L H P
Sbjct: 147 LPVPGARPPPGTPCRVTGWGSL-RPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQ 205
Query: 181 SVK-----SCCEFIRECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYT 235
+ + S C + + DSG L C +W+ +GVVSW C + PG+YT
Sbjct: 206 AERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPGVYT 265
Query: 236 STAHFNQWIRTEVA 249
S A ++ WI+ V+
Sbjct: 266 SVATYSPWIQARVS 279
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 132 bits (332), Expect = 3e-31
Identities = 75/237 (31%), Positives = 121/237 (51%), Gaps = 29/237 (12%)
Query: 37 TNVSCRVVKGKLVEVGKWPWQVSI---LFLGTYICSGSLIHHQWVLTAAHCLQRFKDLSL 93
T S R+V G G+WPWQVS+ L ++C GSLI HQWVLTAAHC +
Sbjct: 385 TKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDV 444
Query: 94 YSVMVGVHQRPENSTQLPLTRM---VIHKDFS-NLMSQDIALLKLRDSISWSPFVQPVCL 149
+ + G+ + + P +++ +IH+++ + + DIAL+KL+ ++++ F +P+CL
Sbjct: 445 WRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICL 504
Query: 150 PNIKFKPSIGSMCWVIGWGTTGKKGFL-------NHPDSVKSCCEFIRECFQFTLTV--- 199
P+ +I + CWV GWG + +KG + N P C+ + ++ T +
Sbjct: 505 PSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCA 564
Query: 200 ------------DSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWI 244
DSG LVC+ + W +G+ SW C +R PG+YT A + WI
Sbjct: 565 GYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621
>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
Length = 567
Score = 130 bits (326), Expect = 2e-30
Identities = 82/251 (32%), Positives = 123/251 (49%), Gaps = 34/251 (13%)
Query: 34 CGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHC--LQRFKDL 91
CG ++ R+V G L KWPWQVS+ F T+IC G+LI QWVLTAAHC + R K L
Sbjct: 317 CGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVL 376
Query: 92 SLYSVMVG---VHQRPENSTQLPLTRMVIHKDFSNLMSQ-DIALLKLRDSISWSPFVQPV 147
+ V G +HQ PE ++ + ++I+ ++++ DIAL++L ++ S + P
Sbjct: 377 EGWKVYAGTSNLHQLPEAAS---IAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPA 433
Query: 148 CLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHP---------DSVKSCCEFIRECFQFTLT 198
CLP S+ CW+ G+G T + P K C +++ T
Sbjct: 434 CLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPR 493
Query: 199 V---------------DSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQW 243
+ DSG LVC+ + W GV SW CGQR+ PG+YT W
Sbjct: 494 MMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPW 553
Query: 244 IRTEV-ANIRF 253
I +++ + +RF
Sbjct: 554 IYSKMESEVRF 564
>gi|5803197 testisin isoform 1 [Homo sapiens]
Length = 314
Score = 129 bits (325), Expect = 2e-30
Identities = 73/254 (28%), Positives = 120/254 (47%), Gaps = 38/254 (14%)
Query: 34 CGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQRFKDLS- 92
CG+ ++ R+V G+ E+G+WPWQ S+ +++C SL+ H+W LTAAHC + + DLS
Sbjct: 33 CGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSD 92
Query: 93 ---------LYSVMVGVHQRPENSTQLPLTRMVIHKDFSNLMSQDIALLKLRDSISWSPF 143
+ M T+ ++ + + + DIAL+KL ++++
Sbjct: 93 PSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKH 152
Query: 144 VQPVCLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHPDSVK---------SCCEFIRECFQ 194
+QP+CL F+ + CWV GWG + L P +++ S C + +
Sbjct: 153 IQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYS 212
Query: 195 FTLTV-------------------DSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYT 235
F + DSG L C + W QIGVVSW CG+ + PG+YT
Sbjct: 213 FRKDIFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYT 272
Query: 236 STAHFNQWIRTEVA 249
+ +H +WI+ +A
Sbjct: 273 NISHHFEWIQKLMA 286
>gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens]
Length = 410
Score = 129 bits (324), Expect = 3e-30
Identities = 79/249 (31%), Positives = 120/249 (48%), Gaps = 45/249 (18%)
Query: 32 RACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQRFKDL 91
+ACG VS R++ G KWPWQVS+ + C GSLI +WVLTAAHC+ F+
Sbjct: 154 QACGH-RVS-RMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCV--FRGC 209
Query: 92 SLYS---VMVGVHQRPENSTQLPLTRMVIHKDFSNLMSQDIALLKLRDSISWSPFVQPVC 148
++ G+ + + L + DF+ L S DIAL L S+++S +QP C
Sbjct: 210 GWEGGRWLLAGIGRWDQAWKHLEDIIFPSNFDFATLTS-DIALALLAYSVNYSSHIQPAC 268
Query: 149 LPNIKFKPSIGSMCWVIGWGTTGKK--------------GFLNHPDSVKSCCEFIR---- 190
LP F+ G+ CWV GWG + + H + CCE ++
Sbjct: 269 LPEKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRH----EKCCEMLKNKNI 324
Query: 191 ---------------ECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYT 235
+ + DSG LVC+++ TW+Q+G+VSW CG++ +PG+YT
Sbjct: 325 SKSKMVTRGTVCGYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYT 384
Query: 236 STAHFNQWI 244
+ + +WI
Sbjct: 385 EVSFYKKWI 393
>gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo
sapiens]
Length = 410
Score = 129 bits (324), Expect = 3e-30
Identities = 79/249 (31%), Positives = 120/249 (48%), Gaps = 45/249 (18%)
Query: 32 RACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQRFKDL 91
+ACG VS R++ G KWPWQVS+ + C GSLI +WVLTAAHC+ F+
Sbjct: 154 QACGH-RVS-RMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCV--FRGC 209
Query: 92 SLYS---VMVGVHQRPENSTQLPLTRMVIHKDFSNLMSQDIALLKLRDSISWSPFVQPVC 148
++ G+ + + L + DF+ L S DIAL L S+++S +QP C
Sbjct: 210 GWEGGRWLLAGIGRWDQAWKHLEDIIFPSNFDFATLTS-DIALALLAYSVNYSSHIQPAC 268
Query: 149 LPNIKFKPSIGSMCWVIGWGTTGKK--------------GFLNHPDSVKSCCEFIR---- 190
LP F+ G+ CWV GWG + + H + CCE ++
Sbjct: 269 LPEKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRH----EKCCEMLKNKNI 324
Query: 191 ---------------ECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYT 235
+ + DSG LVC+++ TW+Q+G+VSW CG++ +PG+YT
Sbjct: 325 SKSKMVTRGTVCGYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYT 384
Query: 236 STAHFNQWI 244
+ + +WI
Sbjct: 385 EVSFYKKWI 393
>gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo
sapiens]
Length = 410
Score = 129 bits (324), Expect = 3e-30
Identities = 79/249 (31%), Positives = 120/249 (48%), Gaps = 45/249 (18%)
Query: 32 RACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQRFKDL 91
+ACG VS R++ G KWPWQVS+ + C GSLI +WVLTAAHC+ F+
Sbjct: 154 QACGH-RVS-RMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCV--FRGC 209
Query: 92 SLYS---VMVGVHQRPENSTQLPLTRMVIHKDFSNLMSQDIALLKLRDSISWSPFVQPVC 148
++ G+ + + L + DF+ L S DIAL L S+++S +QP C
Sbjct: 210 GWEGGRWLLAGIGRWDQAWKHLEDIIFPSNFDFATLTS-DIALALLAYSVNYSSHIQPAC 268
Query: 149 LPNIKFKPSIGSMCWVIGWGTTGKK--------------GFLNHPDSVKSCCEFIR---- 190
LP F+ G+ CWV GWG + + H + CCE ++
Sbjct: 269 LPEKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRH----EKCCEMLKNKNI 324
Query: 191 ---------------ECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYT 235
+ + DSG LVC+++ TW+Q+G+VSW CG++ +PG+YT
Sbjct: 325 SKSKMVTRGTVCGYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYT 384
Query: 236 STAHFNQWI 244
+ + +WI
Sbjct: 385 EVSFYKKWI 393
>gi|4506153 prostasin preproprotein [Homo sapiens]
Length = 343
Score = 128 bits (322), Expect = 5e-30
Identities = 87/284 (30%), Positives = 127/284 (44%), Gaps = 37/284 (13%)
Query: 4 GPGDLQSLTSPLSSARLDYQPSIEGPWLRACGQTNVSCRVVKGKLVEVGKWPWQVSILFL 63
GPG L ++ L L EG CG R+ G G+WPWQVSI +
Sbjct: 8 GPGQLGAVAILLYLGLLRSGTGAEGAEA-PCGVAP-QARITGGSSAVAGQWPWQVSITYE 65
Query: 64 GTYICSGSLIHHQWVLTAAHCLQRFKDLSLYSVMVGVHQ---RPENSTQLPLTRMVIHKD 120
G ++C GSL+ QWVL+AAHC Y V +G HQ E++ L ++ H
Sbjct: 66 GVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPS 125
Query: 121 FSNLMSQ-DIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHP 179
+ SQ DIALL+L I++S +++P+CLP G C V GWG L P
Sbjct: 126 YLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTP 185
Query: 180 DSV---------KSCC-------------EFIRE---CFQF------TLTVDSGSSLVCQ 208
+ + C F++E C + DSG L C
Sbjct: 186 KPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCP 245
Query: 209 MDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWIRTEVANIR 252
++ W G+VSW +CG R+ PG+YT + + WI+++V ++
Sbjct: 246 VEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQ 289
>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
Length = 321
Score = 126 bits (317), Expect = 2e-29
Identities = 90/280 (32%), Positives = 122/280 (43%), Gaps = 49/280 (17%)
Query: 34 CGQTNVSC---RVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQRFKD 90
CG+ VS R+V G G WPWQ S+ ++C GSL+ QWVLTAAHC +
Sbjct: 26 CGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLN 85
Query: 91 LSLYSVMVG---VHQRPENSTQLPLTRMVIHKDFSNL--MSQDIALLKLRDSISWSPFVQ 145
S Y V +G + P ST + ++++H S S DIAL++L ++ S +
Sbjct: 86 SSDYQVHLGELEITLSPHFST---VRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRIL 142
Query: 146 PVCLPNIKFKPSIGSMCWVIGWGTT------------------------------GKKGF 175
PVCLP G CWV GWG T G G
Sbjct: 143 PVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVKVSVVDTETCRRDYPGPGGS 202
Query: 176 LNHPDSVKSCCEFIRECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYT 235
+ PD + C + Q DSG LVCQ++ W+Q G+VSW CG+ + PG+YT
Sbjct: 203 ILQPDML--CARGPGDACQ----DDSGGPLVCQVNGAWVQAGIVSWGEGCGRPNRPGVYT 256
Query: 236 STAHFNQWIRTEVANIRFISRAGP--AFLSPVFLTGYILL 273
+ WIR + P L+ FL G LL
Sbjct: 257 RVPAYVNWIRRHITASGGSESGYPRLPLLAGFFLPGLFLL 296
>gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
Length = 275
Score = 126 bits (316), Expect = 2e-29
Identities = 84/247 (34%), Positives = 111/247 (44%), Gaps = 35/247 (14%)
Query: 33 ACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTY---ICSGSLIHHQWVLTAAHCL-QRF 88
A GQ +V G+ KWPWQVS+ G Y C GSLIH QWVLTAAHC+
Sbjct: 21 APGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDV 80
Query: 89 KDLSLYSVMVGVHQRPENSTQLPLTRMVIHKDF-SNLMSQDIALLKLRDSISWSPFVQPV 147
KDL+ V + LP++R+++H F + + DIALL+L + ++ S V V
Sbjct: 81 KDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTV 140
Query: 148 CLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHPDSVKS---------CCEFIRECFQFT-- 196
LP G CWV GWG L P +K C+ +T
Sbjct: 141 TLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGD 200
Query: 197 -------------------LTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTST 237
DSG LVC+++ TW+Q GVVSW C Q + PGIYT
Sbjct: 201 DVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRV 260
Query: 238 AHFNQWI 244
++ WI
Sbjct: 261 TYYLDWI 267
>gi|4503627 coagulation factor XI precursor [Homo sapiens]
Length = 625
Score = 126 bits (316), Expect = 2e-29
Identities = 77/253 (30%), Positives = 122/253 (48%), Gaps = 34/253 (13%)
Query: 26 IEGPWLRACGQTN-----VSCRVVKGKLVEVGKWPWQVSILFLGT---YICSGSLIHHQW 77
I G LR C N + R+V G G+WPWQV++ ++C GS+I +QW
Sbjct: 366 ISGYTLRLCKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQW 425
Query: 78 VLTAAHC---LQRFKDLSLYSVMVGVHQRPENSTQLPLTRMVIHKDFSNLMS-QDIALLK 133
+LTAAHC ++ K L +YS ++ + E+++ + ++IH + S DIALLK
Sbjct: 426 ILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLK 485
Query: 134 LRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTG---------------------- 171
L +++++ +P+CLP+ + I + CWV GWG
Sbjct: 486 LETTVNYTDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEEC 545
Query: 172 KKGFLNHPDSVKSCCEFIRECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFP 231
+K + H + K C RE + DSG L C+ ++ W +G+ SW C QR P
Sbjct: 546 QKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERP 605
Query: 232 GIYTSTAHFNQWI 244
G+YT+ + WI
Sbjct: 606 GVYTNVVEYVDWI 618
>gi|11545839 protease, serine, 22 [Homo sapiens]
Length = 317
Score = 126 bits (316), Expect = 2e-29
Identities = 90/299 (30%), Positives = 134/299 (44%), Gaps = 36/299 (12%)
Query: 2 ACGPGDLQSLTSPLSSARLDYQPSIEGPWLRACGQTNVSCRVVKGKLVEVGKWPWQVSIL 61
A G G L + TS L A + P ACG+ RVV G+ +WPW VSI
Sbjct: 9 ALGGGCLGTFTSLLLLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQ 68
Query: 62 FLGTYICSGSLIHHQWVLTAAHCLQ-RFKDLSLYSVMVGVHQ---RPENSTQLPLTRMVI 117
GT+ C+GSL+ +WV+TAAHC + L+SV++G Q S ++ + +
Sbjct: 69 KNGTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQKVGVAWVEP 128
Query: 118 HKDFS--NLMSQDIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKGF 175
H +S DIAL++L SI +S V P+CLP+ + CW+ GWG+
Sbjct: 129 HPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGVP 188
Query: 176 LNHPDSVKS----------------------------CCEFIRECFQFTLTVDSGSSLVC 207
L HP +++ C E + DSG L+C
Sbjct: 189 LPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERDACLGDSGGPLMC 248
Query: 208 QMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWIRTEVANIRFISRA--GPAFLSP 264
Q+D W+ G++SW C +R+ PG+Y S + W+ V ++ RA G A +P
Sbjct: 249 QVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLRGRAQGGGALRAP 307
>gi|33186882 testis serine protease 2 [Homo sapiens]
Length = 293
Score = 125 bits (314), Expect = 4e-29
Identities = 74/227 (32%), Positives = 113/227 (49%), Gaps = 39/227 (17%)
Query: 34 CGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQ-RFKDLS 92
CG+T + R+V G E G+WPWQVS+ G +IC G+L+ WVLTA HC+ RF
Sbjct: 73 CGRTPL--RIVGGVDAEEGRWPWQVSVRTKGRHICGGTLVTATWVLTAGHCISSRFH--- 127
Query: 93 LYSVMVGVHQRPENSTQLPLT--RMVIHKDFSNLMS--QDIALLKLRDSISWSPFVQPVC 148
YSV +G +T + ++ R +H FS + + D+ALL+L+ ++++ +QP+C
Sbjct: 128 -YSVKMGDRSVYNENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFTSNIQPIC 186
Query: 149 LPNIKFKPSIGSMCWVIGWGTTGKKG-----FLNHPDSVKSCCEFIRECFQFTLTV---- 199
+P F+ + CWV GWG T ++ L D C E + Q L+
Sbjct: 187 IPQENFQVEGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKALSSTKDV 246
Query: 200 -------------------DSGSSLVCQMDKTWIQIGVVSWSFSCGQ 227
DSG L C+ + TW+Q+G+VSW CG+
Sbjct: 247 IIKGMVCGYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR 293
>gi|21614531 testisin isoform 2 [Homo sapiens]
Length = 312
Score = 125 bits (314), Expect = 4e-29
Identities = 74/252 (29%), Positives = 121/252 (48%), Gaps = 36/252 (14%)
Query: 34 CGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQR-FKDLS 92
CG+ ++ R+V G+ E+G+WPWQ S+ +++C SL+ H+W LTAAHC + D S
Sbjct: 33 CGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETDLSDPS 92
Query: 93 LYSVMVG-VHQRPE------NSTQLPLTRMVIHKDFSNLMSQDIALLKLRDSISWSPFVQ 145
+ V G + P T+ ++ + + + DIAL+KL ++++ +Q
Sbjct: 93 GWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQ 152
Query: 146 PVCLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHPDSVK---------SCCEFIRECFQFT 196
P+CL F+ + CWV GWG + L P +++ S C + + F
Sbjct: 153 PICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFR 212
Query: 197 LTV-------------------DSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTST 237
+ DSG L C + W QIGVVSW CG+ + PG+YT+
Sbjct: 213 KDIFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNI 272
Query: 238 AHFNQWIRTEVA 249
+H +WI+ +A
Sbjct: 273 SHHFEWIQKLMA 284
>gi|110578663 hypothetical protein LOC203074 [Homo sapiens]
Length = 352
Score = 124 bits (311), Expect = 9e-29
Identities = 81/239 (33%), Positives = 117/239 (48%), Gaps = 33/239 (13%)
Query: 35 GQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQRFKDL--S 92
G+T S R+ G EVG++PWQVSI C GS+++ W+LTAAHCL ++L
Sbjct: 61 GRTRYS-RITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYS-EELFPE 118
Query: 93 LYSVMVGVHQRPENSTQL-PLTRMVIHKDFSNL-MSQDIALLKLRDSISWSPFVQPVCLP 150
SV++G + S ++ + +++HKDF M DIALL L I P+CLP
Sbjct: 119 ELSVVLGTNDLTSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLP 178
Query: 151 NIKFKPSIGSMCWVIGWGTTG-------KKGFLNHPDSVKS----------------CCE 187
+ P+ CWV GWG T K + P + C
Sbjct: 179 T-QPGPATWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFPKLTKNMLCAG 237
Query: 188 FIRECFQFTLTVDSGSSLVC--QMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWI 244
+ E + DSG LVC + + W Q+G++SW SCG+++ PGIYTS ++N WI
Sbjct: 238 YKNESYD-ACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWI 295
>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
Length = 275
Score = 124 bits (310), Expect = 1e-28
Identities = 83/247 (33%), Positives = 110/247 (44%), Gaps = 35/247 (14%)
Query: 33 ACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTY---ICSGSLIHHQWVLTAAHCL-QRF 88
A GQ +V G+ KWPWQVS+ Y C GSLIH QWVLTAAHC+
Sbjct: 21 APGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCVGPDV 80
Query: 89 KDLSLYSVMVGVHQRPENSTQLPLTRMVIHKDF-SNLMSQDIALLKLRDSISWSPFVQPV 147
KDL+ V + LP++R+++H F + + DIALL+L + ++ S V V
Sbjct: 81 KDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTV 140
Query: 148 CLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHPDSVKS---------CCEFIRECFQFT-- 196
LP G CWV GWG L P +K C+ +T
Sbjct: 141 TLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGD 200
Query: 197 -------------------LTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTST 237
DSG LVC+++ TW+Q GVVSW C Q + PGIYT
Sbjct: 201 DVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRV 260
Query: 238 AHFNQWI 244
++ WI
Sbjct: 261 TYYLDWI 267
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 123 bits (308), Expect = 2e-28
Identities = 71/243 (29%), Positives = 110/243 (45%), Gaps = 27/243 (11%)
Query: 33 ACG-QTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQRFKDL 91
ACG + S R+V G + + +WPWQ S+ F G ++C GS+I W++TAAHC+
Sbjct: 206 ACGHRRGYSSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYDLYLP 265
Query: 92 SLYSVMVGVHQRPENSTQLPLTRMVIH--KDFSNLMSQDIALLKLRDSISWSPFVQPVCL 149
+++ VG+ +N L +++ K + DIAL+KL ++++ +QPVCL
Sbjct: 266 KSWTIQVGLVSLLDNPAPSHLVEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCL 325
Query: 150 PNIKFKPSIGSMCWVIGWGTTG------------------KKGFLNHPDSVKSCCEFIRE 191
PN + G +CW GWG T NH D
Sbjct: 326 PNSEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSML 385
Query: 192 CFQF------TLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWIR 245
C + + DSG LVCQ + W +G S+ C + + PG+YT F WI
Sbjct: 386 CAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIH 445
Query: 246 TEV 248
++
Sbjct: 446 EQM 448
>gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo
sapiens]
Length = 432
Score = 122 bits (307), Expect = 3e-28
Identities = 75/236 (31%), Positives = 114/236 (48%), Gaps = 25/236 (10%)
Query: 33 ACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQRFKDLS 92
ACG++ + RVV G+ V WPWQVSI + ++C GS++ WVLTAAHC ++ D+
Sbjct: 190 ACGKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVF 249
Query: 93 LYSVMVGVHQRPENSTQLPLTRMVIHKDFSNLMSQDIALLKLRDSISWSPFVQPVCLPNI 152
+ V G + + ++I + DIAL+KL+ +++S V+P+CLP
Sbjct: 250 NWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFF 309
Query: 153 KFKPSIGSMCWVIGWGTTGKKG------------------FLNHPDSV------KSCCEF 188
+ + + W+IGWG T + G N D+ K C
Sbjct: 310 DEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADDAYQGEVTEKMMCAG 369
Query: 189 IRECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWI 244
I E T DSG L+ Q D+ W +G+VSW + CG PG+YT + + WI
Sbjct: 370 IPEGGVDTCQGDSGGPLMYQSDQ-WHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWI 424
>gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo
sapiens]
Length = 437
Score = 122 bits (307), Expect = 3e-28
Identities = 75/236 (31%), Positives = 114/236 (48%), Gaps = 25/236 (10%)
Query: 33 ACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCLQRFKDLS 92
ACG++ + RVV G+ V WPWQVSI + ++C GS++ WVLTAAHC ++ D+
Sbjct: 195 ACGKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVF 254
Query: 93 LYSVMVGVHQRPENSTQLPLTRMVIHKDFSNLMSQDIALLKLRDSISWSPFVQPVCLPNI 152
+ V G + + ++I + DIAL+KL+ +++S V+P+CLP
Sbjct: 255 NWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFF 314
Query: 153 KFKPSIGSMCWVIGWGTTGKKG------------------FLNHPDSV------KSCCEF 188
+ + + W+IGWG T + G N D+ K C
Sbjct: 315 DEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADDAYQGEVTEKMMCAG 374
Query: 189 IRECFQFTLTVDSGSSLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWI 244
I E T DSG L+ Q D+ W +G+VSW + CG PG+YT + + WI
Sbjct: 375 IPEGGVDTCQGDSGGPLMYQSDQ-WHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWI 429
>gi|7019563 testes-specific protease 50 [Homo sapiens]
Length = 385
Score = 122 bits (306), Expect = 4e-28
Identities = 86/281 (30%), Positives = 132/281 (46%), Gaps = 54/281 (19%)
Query: 12 TSPLSSARLDYQ-PSIEG---PWLRACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYI 67
T L S ++ Q P EG P+ R+CG + ++ +WPW VS+ GT+I
Sbjct: 79 TQTLPSTTMETQFPVSEGKVDPY-RSCGFSYEQDPTLRDPEAVARRWPWMVSVRANGTHI 137
Query: 68 CSGSLIHHQWVLTAAHCLQRFKDLSLYSVMVG---VHQRPENSTQLPLTRMVIHKDFSNL 124
C+G++I QWVLT AHCL ++D+ +YSV VG + Q + ++ +P+ ++++H +
Sbjct: 138 CAGTIIASQWVLTVAHCL-IWRDV-IYSVRVGSPWIDQMTQTASDVPVLQVIMHSRYRAQ 195
Query: 125 -------MSQDIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKG--- 174
+ DI LLKL+ + +S +V+P+CLP + S C V GWG + G
Sbjct: 196 RFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRCTVTGWGLSKADGMWP 255
Query: 175 -----------FLNHPD-------------------SVKSCCEFI-RECFQFTLTVDSGS 203
LN+ + S C E RE F + LT G
Sbjct: 256 QFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCAEDTHREKFCYELT---GE 312
Query: 204 SLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWI 244
LVC M+ TW +G+VSW C + P IY + + WI
Sbjct: 313 PLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWI 353
>gi|222831592 transmembrane protease, serine 7 [Homo sapiens]
Length = 717
Score = 119 bits (298), Expect = 3e-27
Identities = 75/240 (31%), Positives = 114/240 (47%), Gaps = 32/240 (13%)
Query: 42 RVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWVLTAAHCL--QRFKDLSLYSVMVG 99
R++ G G WPWQVS+ F+G+ C S+I +W+L+AAHC R D + ++ +G
Sbjct: 479 RIIGGTDTLEGGWPWQVSLHFVGSAYCGASVISREWLLSAAHCFHGNRLSDPTPWTAHLG 538
Query: 100 VHQRPENSTQLPLTRMVIHKDF-SNLMSQDIALLKLRDSISW----SPFVQPVCLPNIKF 154
++ + P+ R+V+H+ + S DIALL+L SI+W +QP+C+P
Sbjct: 539 MYVQGNAKFVSPVRRIVVHEYYNSQTFDYDIALLQL--SIAWPETLKQLIQPICIPPTGQ 596
Query: 155 KPSIGSMCWVIGWG---TTGKKGFLNHPD------------------SVKSCCEFIRECF 193
+ G CWV GWG KG L + + C I
Sbjct: 597 RVRSGEKCWVTGWGRRHEADNKGSLVLQQAEVELIDQTLCVSTYGIITSRMLCAGIMSGK 656
Query: 194 QFTLTVDSGSSLVC--QMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWIRTEVANI 251
+ DSG L C + D WI G+VSW G+ +FPG+YT ++F WI V ++
Sbjct: 657 RDACKGDSGGPLSCRRKSDGKWILTGIVSWGHGSGRPNFPGVYTRVSNFVPWIHKYVPSL 716
>gi|148231605 ovochymase 2 [Homo sapiens]
Length = 564
Score = 118 bits (295), Expect = 7e-27
Identities = 86/282 (30%), Positives = 122/282 (43%), Gaps = 53/282 (18%)
Query: 29 PWLRACGQT----------NVSCRVVKGKLVEVGKWPWQVSILFLGTYICSGSLIHHQWV 78
P +CGQ+ N+ R++ G VE G +PWQVS+ +IC GS++ QWV
Sbjct: 28 PKAPSCGQSLVKVQPWNYFNIFSRILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWV 87
Query: 79 LTAAHCLQRFKDLSLYSVMVG---VHQRPENSTQLPLTRMVIHKDFSNL--MSQDIALLK 133
+TAAHC+ +S +V G + Q L + ++IH FS M DIALLK
Sbjct: 88 ITAAHCIANRNIVSTLNVTAGEYDLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLK 147
Query: 134 LRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKGFLNHP-DSVKSCCEFIREC 192
+ + + FV P+CLP ++ + G +C GWG + G L+ V EC
Sbjct: 148 MAGAFQFGHFVGPICLPELREQFEAGFICTTAGWGRLTEGGVLSQVLQEVNLPILTWEEC 207
Query: 193 FQFTLTV------------------------DSGSSLVCQMDK-TWIQIGVVSWSFSCGQ 227
LT+ DSG SL+C+ K W GV SW CG+
Sbjct: 208 VAALLTLKRPISGKTFLCTGFPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGR 267
Query: 228 ----------RHFPGIYTSTAHFNQWIRTEV--ANIRFISRA 257
+ PGI+T + WI + N R SRA
Sbjct: 268 GWRNNVRKSDQGSPGIFTDISKVLPWIHEHIQTGNRRKSSRA 309
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.137 0.460
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,327,084
Number of Sequences: 37866
Number of extensions: 475969
Number of successful extensions: 1759
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 167
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1230
Number of HSP's gapped (non-prelim): 267
length of query: 282
length of database: 18,247,518
effective HSP length: 101
effective length of query: 181
effective length of database: 14,423,052
effective search space: 2610572412
effective search space used: 2610572412
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.