Guide to the Human Genome
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Search of human proteins with 116256342

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116256342 novel 58.3 KDA protein isoform 1 [Homo sapiens]
         (511 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116256342 novel 58.3 KDA protein isoform 1 [Homo sapiens]         1016   0.0  
gi|116256344 novel 58.3 KDA protein isoform 2 [Homo sapiens]          969   0.0  
gi|22748695 DEP domain containing 4 [Homo sapiens]                    144   1e-34
gi|38488716 DEP domain containing 1 isoform b [Homo sapiens]          129   8e-30
gi|223633999 DEP domain containing 1B isoform 1 [Homo sapiens]        115   9e-26
gi|223633997 DEP domain containing 1B isoform 2 [Homo sapiens]         84   2e-16
gi|166295188 DEP domain containing 1 isoform a [Homo sapiens]          73   7e-13
gi|70980531 GGA binding partner [Homo sapiens]                         39   0.015
gi|38569484 kinesin family member 21A [Homo sapiens]                   36   0.095
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ...    35   0.12 
gi|22749359 phosphatidylinositol-3-phosphate 5-kinase type III i...    35   0.12 
gi|189571664 DEP domain containing 6 [Homo sapiens]                    33   0.47 
gi|5032031 RNA binding motif protein 5 [Homo sapiens]                  33   0.47 
gi|208609990 nucleoporin 93kDa [Homo sapiens]                          33   0.81 
gi|223718070 retinoic acid receptor, alpha isoform 4 [Homo sapiens]    31   3.1  
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]    31   3.1  
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]     31   3.1  
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]      31   3.1  
gi|115583670 T-cell lymphoma invasion and metastasis 1 [Homo sap...    31   3.1  
gi|126116589 fibrocystin L [Homo sapiens]                              31   3.1  
gi|108773787 retinoblastoma 1 [Homo sapiens]                           30   4.0  
gi|164519076 transmembrane 9 superfamily protein member 4 [Homo ...    30   5.2  
gi|34452709 bromodomain containing 8 isoform 3 [Homo sapiens]          30   6.8  
gi|34452705 bromodomain containing 8 isoform 1 [Homo sapiens]          30   6.8  
gi|214010216 SMC6 protein [Homo sapiens]                               30   6.8  
gi|13375848 SMC6 protein [Homo sapiens]                                30   6.8  
gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]         29   8.9  
gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens]         29   8.9  

>gi|116256342 novel 58.3 KDA protein isoform 1 [Homo sapiens]
          Length = 511

 Score = 1016 bits (2626), Expect = 0.0
 Identities = 511/511 (100%), Positives = 511/511 (100%)

Query: 1   MATVQEKAAALNLSALHSPAHRPPGFSVAQKPFGATYVWSSIINTLQTQVEVKKRRHRLK 60
           MATVQEKAAALNLSALHSPAHRPPGFSVAQKPFGATYVWSSIINTLQTQVEVKKRRHRLK
Sbjct: 1   MATVQEKAAALNLSALHSPAHRPPGFSVAQKPFGATYVWSSIINTLQTQVEVKKRRHRLK 60

Query: 61  RHNDCFVGSEAVDVIFSHLIQNKYFGDVDIPRAKVVRVCQALMDYKVFEAVPTKVFGKDK 120
           RHNDCFVGSEAVDVIFSHLIQNKYFGDVDIPRAKVVRVCQALMDYKVFEAVPTKVFGKDK
Sbjct: 61  RHNDCFVGSEAVDVIFSHLIQNKYFGDVDIPRAKVVRVCQALMDYKVFEAVPTKVFGKDK 120

Query: 121 KPTFEDSSCSLYRFTTIPNQDSQLGKENKLYSPARYADALFKSSDIRSASLEDLWENLSL 180
           KPTFEDSSCSLYRFTTIPNQDSQLGKENKLYSPARYADALFKSSDIRSASLEDLWENLSL
Sbjct: 121 KPTFEDSSCSLYRFTTIPNQDSQLGKENKLYSPARYADALFKSSDIRSASLEDLWENLSL 180

Query: 181 KPANSPHVNISATLSPQVINEVWQEETIGRLLQLVDLPLLDSLLKQQEAVPKIPQPKRQS 240
           KPANSPHVNISATLSPQVINEVWQEETIGRLLQLVDLPLLDSLLKQQEAVPKIPQPKRQS
Sbjct: 181 KPANSPHVNISATLSPQVINEVWQEETIGRLLQLVDLPLLDSLLKQQEAVPKIPQPKRQS 240

Query: 241 TMVNSSNYLDRGILKAYSDSQEDEWLSAAIDCLEYLPDQMVVEISRSFPEQPDRTDLVKE 300
           TMVNSSNYLDRGILKAYSDSQEDEWLSAAIDCLEYLPDQMVVEISRSFPEQPDRTDLVKE
Sbjct: 241 TMVNSSNYLDRGILKAYSDSQEDEWLSAAIDCLEYLPDQMVVEISRSFPEQPDRTDLVKE 300

Query: 301 LLFDAIGRYYSSREPLLNHLSDVHNGIAELLVNGKTEIALEATQLLLKLLDFQNREEFRR 360
           LLFDAIGRYYSSREPLLNHLSDVHNGIAELLVNGKTEIALEATQLLLKLLDFQNREEFRR
Sbjct: 301 LLFDAIGRYYSSREPLLNHLSDVHNGIAELLVNGKTEIALEATQLLLKLLDFQNREEFRR 360

Query: 361 LLYFMAVAANPSEFKLQKESDNRMVVKRIFSKAIVDNKNLSKGKTDLLVLFLMDHQKDVF 420
           LLYFMAVAANPSEFKLQKESDNRMVVKRIFSKAIVDNKNLSKGKTDLLVLFLMDHQKDVF
Sbjct: 361 LLYFMAVAANPSEFKLQKESDNRMVVKRIFSKAIVDNKNLSKGKTDLLVLFLMDHQKDVF 420

Query: 421 KIPGTLHKIVSVKLMAIQNGRDPNRDAGYIYCQRIDQRDYSNNTEKTTKDELLNLLKTLD 480
           KIPGTLHKIVSVKLMAIQNGRDPNRDAGYIYCQRIDQRDYSNNTEKTTKDELLNLLKTLD
Sbjct: 421 KIPGTLHKIVSVKLMAIQNGRDPNRDAGYIYCQRIDQRDYSNNTEKTTKDELLNLLKTLD 480

Query: 481 EDSKLSAKEKKKLLGQFYKCHPDIFIEHFGD 511
           EDSKLSAKEKKKLLGQFYKCHPDIFIEHFGD
Sbjct: 481 EDSKLSAKEKKKLLGQFYKCHPDIFIEHFGD 511


>gi|116256344 novel 58.3 KDA protein isoform 2 [Homo sapiens]
          Length = 502

 Score =  969 bits (2505), Expect = 0.0
 Identities = 487/487 (100%), Positives = 487/487 (100%)

Query: 25  GFSVAQKPFGATYVWSSIINTLQTQVEVKKRRHRLKRHNDCFVGSEAVDVIFSHLIQNKY 84
           GFSVAQKPFGATYVWSSIINTLQTQVEVKKRRHRLKRHNDCFVGSEAVDVIFSHLIQNKY
Sbjct: 16  GFSVAQKPFGATYVWSSIINTLQTQVEVKKRRHRLKRHNDCFVGSEAVDVIFSHLIQNKY 75

Query: 85  FGDVDIPRAKVVRVCQALMDYKVFEAVPTKVFGKDKKPTFEDSSCSLYRFTTIPNQDSQL 144
           FGDVDIPRAKVVRVCQALMDYKVFEAVPTKVFGKDKKPTFEDSSCSLYRFTTIPNQDSQL
Sbjct: 76  FGDVDIPRAKVVRVCQALMDYKVFEAVPTKVFGKDKKPTFEDSSCSLYRFTTIPNQDSQL 135

Query: 145 GKENKLYSPARYADALFKSSDIRSASLEDLWENLSLKPANSPHVNISATLSPQVINEVWQ 204
           GKENKLYSPARYADALFKSSDIRSASLEDLWENLSLKPANSPHVNISATLSPQVINEVWQ
Sbjct: 136 GKENKLYSPARYADALFKSSDIRSASLEDLWENLSLKPANSPHVNISATLSPQVINEVWQ 195

Query: 205 EETIGRLLQLVDLPLLDSLLKQQEAVPKIPQPKRQSTMVNSSNYLDRGILKAYSDSQEDE 264
           EETIGRLLQLVDLPLLDSLLKQQEAVPKIPQPKRQSTMVNSSNYLDRGILKAYSDSQEDE
Sbjct: 196 EETIGRLLQLVDLPLLDSLLKQQEAVPKIPQPKRQSTMVNSSNYLDRGILKAYSDSQEDE 255

Query: 265 WLSAAIDCLEYLPDQMVVEISRSFPEQPDRTDLVKELLFDAIGRYYSSREPLLNHLSDVH 324
           WLSAAIDCLEYLPDQMVVEISRSFPEQPDRTDLVKELLFDAIGRYYSSREPLLNHLSDVH
Sbjct: 256 WLSAAIDCLEYLPDQMVVEISRSFPEQPDRTDLVKELLFDAIGRYYSSREPLLNHLSDVH 315

Query: 325 NGIAELLVNGKTEIALEATQLLLKLLDFQNREEFRRLLYFMAVAANPSEFKLQKESDNRM 384
           NGIAELLVNGKTEIALEATQLLLKLLDFQNREEFRRLLYFMAVAANPSEFKLQKESDNRM
Sbjct: 316 NGIAELLVNGKTEIALEATQLLLKLLDFQNREEFRRLLYFMAVAANPSEFKLQKESDNRM 375

Query: 385 VVKRIFSKAIVDNKNLSKGKTDLLVLFLMDHQKDVFKIPGTLHKIVSVKLMAIQNGRDPN 444
           VVKRIFSKAIVDNKNLSKGKTDLLVLFLMDHQKDVFKIPGTLHKIVSVKLMAIQNGRDPN
Sbjct: 376 VVKRIFSKAIVDNKNLSKGKTDLLVLFLMDHQKDVFKIPGTLHKIVSVKLMAIQNGRDPN 435

Query: 445 RDAGYIYCQRIDQRDYSNNTEKTTKDELLNLLKTLDEDSKLSAKEKKKLLGQFYKCHPDI 504
           RDAGYIYCQRIDQRDYSNNTEKTTKDELLNLLKTLDEDSKLSAKEKKKLLGQFYKCHPDI
Sbjct: 436 RDAGYIYCQRIDQRDYSNNTEKTTKDELLNLLKTLDEDSKLSAKEKKKLLGQFYKCHPDI 495

Query: 505 FIEHFGD 511
           FIEHFGD
Sbjct: 496 FIEHFGD 502


>gi|22748695 DEP domain containing 4 [Homo sapiens]
          Length = 294

 Score =  144 bits (364), Expect = 1e-34
 Identities = 87/233 (37%), Positives = 133/233 (57%), Gaps = 13/233 (5%)

Query: 32  PFGATYVWSSIINTLQTQVEVKKRRHRLKRHNDCFVGSEAVDVIFSHLIQNKYFGDVDIP 91
           PF AT +W  II++LQ QVE+K+RRH L+ + DCF GS+AVDV+ SHL+QN      DI 
Sbjct: 57  PFQATQLWDGIIHSLQAQVEIKRRRHHLQTYKDCFTGSDAVDVVLSHLMQNTCLSSNDIS 116

Query: 92  RAKVVRVCQALMDYKVFEAV-PTKVFGKDKKPTFEDSSCSLYRFTTIPNQDS------QL 144
             K V +CQ LM++KVFE V   K+F K+K+  FEDS+ SLYRF  + N+ S      Q 
Sbjct: 117 CLKGVHLCQVLMNHKVFEPVGMKKLFKKEKELEFEDSNISLYRF--LGNKSSYDCCKRQK 174

Query: 145 GKENKLYSPARYADALFK---SSDIRSASLEDLWENLSLKPANSPHVNISATLSPQVINE 201
             EN+     R    +     + +I    +E+L   ++  PA  P++ +          +
Sbjct: 175 DAENEFNETLRPGYEMISNPLAQEIGEERIEELIHTINGNPALCPNITVQKPFLRLSKED 234

Query: 202 VWQEETIGRLLQLVDLPLLDSLLKQQEAVPKIPQPKRQSTMVNSSNYLDRGIL 254
           VW+E+T+  LLQL+ LP LD++L+       + Q  ++  +V ++  LDR ++
Sbjct: 235 VWKEQTLLCLLQLIHLPFLDNILEPPVKTQNL-QLNKEEDLVITNTCLDRELI 286


>gi|38488716 DEP domain containing 1 isoform b [Homo sapiens]
          Length = 527

 Score =  129 bits (323), Expect = 8e-30
 Identities = 116/516 (22%), Positives = 232/516 (44%), Gaps = 56/516 (10%)

Query: 23  PPGFSVAQKPFGATYVWSSIINTLQTQVEVKKRRHRLKRHNDCFVGSEAVDVIFSHLIQN 82
           PPG      P+ AT +W+ +  + +  + ++K R   K++ +CF   EAVD ++  L  N
Sbjct: 7   PPG------PYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNN 60

Query: 83  KYFGDVDIPRAKVVRVCQALMDYKVFEAVPTKVFGKDKKPTFEDSSCSLYRF------TT 136
             FG  ++ R + +++ +  +   V E +  + +G +      D +  L+RF       T
Sbjct: 61  SNFGP-EVTRQQTIQLLRKFLKNHVIEDIKGR-WGSEN----VDDNNQLFRFPATSPLKT 114

Query: 137 IPNQDSQLGKENKLYSPARYADALFKSSDIRSAS--------LEDLWENLSLKPANSPHV 188
           +P +  +L ++N + + ++  D++FK  ++   +         ++  E +  +  N    
Sbjct: 115 LPRRYPEL-RKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQE 173

Query: 189 NI--SATLSPQVINEVWQEETIGRLLQLVDLPLLDSLLKQQEAVPKIPQPKRQSTMVNSS 246
           N   +  LS + + EVW+   +  L  ++ +P L+ ++  ++ +P       Q  M N +
Sbjct: 174 NAIDNRELSQEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIP-------QYIMYNMA 226

Query: 247 NYLDRGILKAYSDSQE-DEWLSAAIDCLEYLPDQMVVEISRSFPEQPDRTDLVKELLFDA 305
           N   RG++   + S +   W+ +A+ CL   P         +    P      +++    
Sbjct: 227 NTSKRGVVILQNKSDDLPHWVLSAMKCLANWP-------RSNDMNNPTYVGFERDVFRTI 279

Query: 306 IGRYYSSREPLLN-HLSDVHNGIAELLVNGKTEIALEATQLLLKLLDFQNREEFRRLLYF 364
              +    EPLL     ++   I  LL      +A++A QL   LL   NR + + L+  
Sbjct: 280 ADYFLDLPEPLLTFEYYELFVNILGLLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMRM 339

Query: 365 MA-VAANPSEFKLQKESDNRMVVKRIFSKAIV---DNKNLSKGKTDLLVLFLMDHQKDVF 420
           ++ ++ N    KL      R ++   FS+ ++   +  +L +     LV FLMDH +++ 
Sbjct: 340 ISRMSQNVDMPKLHDAMGTRSLMIHTFSRCVLCCAEEVDLDELLAGRLVSFLMDHHQEIL 399

Query: 421 KIPGTLHKIVSVKLMAIQNGRDPNRDAG-------YIYCQRIDQRDYSNNTEKTTKDELL 473
           ++P  L   V   L  ++ G   N   G       Y YC++I  +++      T++  + 
Sbjct: 400 QVPSYLQTAVEKHLDYLKKGHIENPGDGLFAPLPTYSYCKQISAQEFDEQKVSTSQAAIA 459

Query: 474 NLLKTLDEDSKLSAKEKKKLLGQFYKCHPDIFIEHF 509
            LL+ + ++  L  KEK+K L QF K +P I+ + F
Sbjct: 460 ELLENIIKNRSLPLKEKRKKLKQFQKEYPLIYQKRF 495


>gi|223633999 DEP domain containing 1B isoform 1 [Homo sapiens]
          Length = 529

 Score =  115 bits (288), Expect = 9e-26
 Identities = 123/507 (24%), Positives = 228/507 (44%), Gaps = 48/507 (9%)

Query: 28  VAQKPFGATYVWSSIINTLQTQVEVKKRRHRLKRHNDCFVGSEAVDVIFSHLIQNKYFGD 87
           V   P+ AT +W+  +   + ++ ++K R R K +  CF  +EAVD +   L  ++ FG 
Sbjct: 6   VGPGPYRATRLWNETVELFRAKMPLRKHRCRFKSYEHCFTAAEAVDWLHELLRCSQNFGP 65

Query: 88  VDIPRAKVVRVCQALMDYKVFEAVPTKVFGKDKKPTFEDSSCSLYRFTTI---------- 137
            ++ R + V++ +  +   V E +     GK  +  FED+   LYRF             
Sbjct: 66  -EVTRKQTVQLLKKFLKNHVIEDIK----GKWGEEDFEDNR-HLYRFPPSSPLKPYPKKP 119

Query: 138 PNQDSQLG-KENKLYSPARYADALFKSSDIRSASLEDLWENLSLKPANSPHVNISATLSP 196
           PNQ   +   E     P    + +     + ++ +     ++++    +  +     L+ 
Sbjct: 120 PNQKDVIKFPEWNDLPPGTSQENIPVRPVVMNSEMWYKRHSIAIGEVPACRLVHRRQLTE 179

Query: 197 QVINEVWQEETIGRLLQLVDLPLLDSLLKQQEAVPKIPQPKRQSTMVNSSNYLDRGILKA 256
             + E+W+  T+  L +++ L  L+ +L  +    K         + N  +   +G++  
Sbjct: 180 ANVEEIWKSMTLSYLQKILGLDSLEEVLDVKLVNSKF-------IIHNVYSVSKQGVVIL 232

Query: 257 YSDSQE-DEWLSAAIDCLEYLPDQMVVEISRSFPEQPDRTDLVKELLFDAIGRYYSS-RE 314
              S+E   W+ +A+ CL   P+        S  +QP      K++ F  I  YY   +E
Sbjct: 233 DDKSKELPHWVLSAMKCLANWPNC-------SDLKQPMYLGFEKDV-FKTIADYYGHLKE 284

Query: 315 PLLN-HLSDVHNGIAELLVNGKTEIALEATQLLLKLLDFQNREEFRRLLYFMA-VAANPS 372
           PLL  HL D    +  LL   K ++A+EA Q+   LL  +NR + + L+  MA +  N  
Sbjct: 285 PLLTFHLFDAFVSVLGLLQ--KEKVAVEAFQICCLLLPPENRRKLQLLMRMMARICLNKE 342

Query: 373 EFKLQKESDNRMVVKRIFSKAIV---DNKNLSKGKTDLLVLFLMDHQKDVFKIPGTLHKI 429
              L      R ++ + FS+ I+   D  +L +     LV FLMD+ +++ K+P  L   
Sbjct: 343 MPPLCDGFGTRTLMVQTFSRCILCSKDEVDLDELLAARLVTFLMDNYQEILKVPLALQTS 402

Query: 430 VSVKLMAIQNG--RDPNRDAGYI-----YCQRIDQRDYSNNTEKTTKDELLNLLKTLDED 482
           +  ++  ++    + P  D         +C++I   ++       +++ L  LL+ +  D
Sbjct: 403 IEERVAHLRRVQIKYPGADMDITLSAPSFCRQISPEEFEYQRSYGSQEPLAALLEEVITD 462

Query: 483 SKLSAKEKKKLLGQFYKCHPDIFIEHF 509
           +KLS KEKKK L QF K +P+++ E F
Sbjct: 463 AKLSNKEKKKKLKQFQKSYPEVYQERF 489


>gi|223633997 DEP domain containing 1B isoform 2 [Homo sapiens]
          Length = 467

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 100/425 (23%), Positives = 187/425 (44%), Gaps = 41/425 (9%)

Query: 28  VAQKPFGATYVWSSIINTLQTQVEVKKRRHRLKRHNDCFVGSEAVDVIFSHLIQNKYFGD 87
           V   P+ AT +W+  +   + ++ ++K R R K +  CF  +EAVD +   L  ++ FG 
Sbjct: 6   VGPGPYRATRLWNETVELFRAKMPLRKHRCRFKSYEHCFTAAEAVDWLHELLRCSQNFGP 65

Query: 88  VDIPRAKVVRVCQALMDYKVFEAVPTKVFGKDKKPTFEDSSCSLYRFTTI---------- 137
            ++ R + V++ +  +   V E +     GK  +  FED+   LYRF             
Sbjct: 66  -EVTRKQTVQLLKKFLKNHVIEDIK----GKWGEEDFEDNR-HLYRFPPSSPLKPYPKKP 119

Query: 138 PNQDSQLG-KENKLYSPARYADALFKSSDIRSASLEDLWENLSLKPANSPHVNISATLSP 196
           PNQ   +   E     P    + +     + ++ +     ++++    +  +     L+ 
Sbjct: 120 PNQKDVIKFPEWNDLPPGTSQENIPVRPVVMNSEMWYKRHSIAIGEVPACRLVHRRQLTE 179

Query: 197 QVINEVWQEETIGRLLQLVDLPLLDSLLKQQEAVPKIPQPKRQSTMVNSSNYLDRGILKA 256
             + E+W+  T+  L +++ L  L+ +L  +    K         + N  +   +G++  
Sbjct: 180 ANVEEIWKSMTLSYLQKILGLDSLEEVLDVKLVNSKF-------IIHNVYSVSKQGVVIL 232

Query: 257 YSDSQE-DEWLSAAIDCLEYLPDQMVVEISRSFPEQPDRTDLVKELLFDAIGRYYSS-RE 314
              S+E   W+ +A+ CL   P+        S  +QP      K++ F  I  YY   +E
Sbjct: 233 DDKSKELPHWVLSAMKCLANWPNC-------SDLKQPMYLGFEKDV-FKTIADYYGHLKE 284

Query: 315 PLLN-HLSDVHNGIAELLVNGKTEIALEATQLLLKLLDFQNREEFRRLLYFMA-VAANPS 372
           PLL  HL D    +  LL   K ++A+EA Q+   LL  +NR + + L+  MA +  N  
Sbjct: 285 PLLTFHLFDAFVSVLGLLQ--KEKVAVEAFQICCLLLPPENRRKLQLLMRMMARICLNKE 342

Query: 373 EFKLQKESDNRMVVKRIFSKAIV---DNKNLSKGKTDLLVLFLMDHQKDVFKIPGTLHKI 429
              L      R ++ + FS+ I+   D  +L +     LV FLMD+ +++ K+P  L   
Sbjct: 343 MPPLCDGFGTRTLMVQTFSRCILCSKDEVDLDELLAARLVTFLMDNYQEILKVPLALQTS 402

Query: 430 VSVKL 434
           +  ++
Sbjct: 403 IEERV 407


>gi|166295188 DEP domain containing 1 isoform a [Homo sapiens]
          Length = 811

 Score = 72.8 bits (177), Expect = 7e-13
 Identities = 59/272 (21%), Positives = 127/272 (46%), Gaps = 37/272 (13%)

Query: 23  PPGFSVAQKPFGATYVWSSIINTLQTQVEVKKRRHRLKRHNDCFVGSEAVDVIFSHLIQN 82
           PPG      P+ AT +W+ +  + +  + ++K R   K++ +CF   EAVD ++  L  N
Sbjct: 7   PPG------PYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNN 60

Query: 83  KYFGDVDIPRAKVVRVCQALMDYKVFEAVPTKVFGKDKKPTFEDSSCSLYRF------TT 136
             FG  ++ R + +++ +  +   V E +  + +G +      D +  L+RF       T
Sbjct: 61  SNFGP-EVTRQQTIQLLRKFLKNHVIEDIKGR-WGSEN----VDDNNQLFRFPATSPLKT 114

Query: 137 IPNQDSQLGKENKLYSPARYADALFKSSDIRSAS--------LEDLWENLSLKPANSPHV 188
           +P +  +L ++N + + ++  D++FK  ++   +         ++  E +  +  N    
Sbjct: 115 LPRRYPEL-RKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQE 173

Query: 189 NI--SATLSPQVINEVWQEETIGRLLQLVDLPLLDSLLKQQEAVPKIPQPKRQSTMVNSS 246
           N   +  LS + + EVW+   +  L  ++ +P L+ ++  ++ +P       Q  M N +
Sbjct: 174 NAIDNRELSQEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIP-------QYIMYNMA 226

Query: 247 NYLDRGILKAYSDSQE-DEWLSAAIDCLEYLP 277
           N   RG++   + S +   W+ +A+ CL   P
Sbjct: 227 NTSKRGVVILQNKSDDLPHWVLSAMKCLANWP 258



 Score = 72.4 bits (176), Expect = 9e-13
 Identities = 53/200 (26%), Positives = 95/200 (47%), Gaps = 11/200 (5%)

Query: 321 SDVHNGIAELLVNGKTEIALEATQLLLKLLDFQNREEFRRLLYFMA-VAANPSEFKLQKE 379
           S +  G   LL      +A++A QL   LL   NR + + L+  ++ ++ N    KL   
Sbjct: 580 SSMLTGTQSLLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHDA 639

Query: 380 SDNRMVVKRIFSKAIV---DNKNLSKGKTDLLVLFLMDHQKDVFKIPGTLHKIVSVKLMA 436
              R ++   FS+ ++   +  +L +     LV FLMDH +++ ++P  L   V   L  
Sbjct: 640 MGTRSLMIHTFSRCVLCCAEEVDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKHLDY 699

Query: 437 IQNGRDPNRDAG-------YIYCQRIDQRDYSNNTEKTTKDELLNLLKTLDEDSKLSAKE 489
           ++ G   N   G       Y YC++I  +++      T++  +  LL+ + ++  L  KE
Sbjct: 700 LKKGHIENPGDGLFAPLPTYSYCKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLPLKE 759

Query: 490 KKKLLGQFYKCHPDIFIEHF 509
           K+K L QF K +P I+ + F
Sbjct: 760 KRKKLKQFQKEYPLIYQKRF 779


>gi|70980531 GGA binding partner [Homo sapiens]
          Length = 441

 Score = 38.5 bits (88), Expect = 0.015
 Identities = 74/352 (21%), Positives = 139/352 (39%), Gaps = 56/352 (15%)

Query: 185 SPHVNISATLSPQVINEVWQEETIGRLLQLVDLPLLDSLLKQQEAVP------KIPQPKR 238
           S H ++  +L P  + +     TI  +    D     S ++ Q+ +       K+ + ++
Sbjct: 93  STHTHLDISLFPLGLTDEKSNGTIALVDDSEDPGANVSNIQLQQKISSLEIKLKVSEEEK 152

Query: 239 Q------STMVNSSNYLDRGILKA-----------YSDSQE------DEWLSAAIDCLEY 275
           Q       +++   N L++G LK            Y + QE      ++   A  + L  
Sbjct: 153 QRIKQDVESLMEKHNVLEKGFLKEKEQEAISFQDRYKELQEKHKQELEDMRKAGHEALSI 212

Query: 276 LPDQMVVEISRSFPEQPDRTDLVKELLFDAIGRYYSSREPLLN----HLSDVHNGIAELL 331
           + D+    +  S  +Q    + +++    AI +     E LLN     L ++ +   ELL
Sbjct: 213 IVDEYKALLQSSVKQQ---VEAIEKQYISAIEKQAHKCEELLNAQHQRLLEMLDTEKELL 269

Query: 332 VNGKTEIALEATQLLLKLLDFQNREEFRRLLYFMAVAANPSEFKLQKESDNRMVVKRIFS 391
                E  ++ +Q   ++L+    EE +R    +  AA     KL+KE+    V+K +  
Sbjct: 270 KEKIKEALIQQSQEQKEILEKCLEEERQRNKEALVSAA-----KLEKEAVKDAVLKVVEE 324

Query: 392 KAIVDNKNLSKGKTDLLVLFLMDHQKDVFKIPGTLHKIVSVKLMAIQNGRDPNRD---AG 448
               + KNL K   +   L+  +H KD  K+   + K       AIQ  R  +++   A 
Sbjct: 325 ----ERKNLEKAHAEERELWKTEHAKDQEKVSQEIQK-------AIQEQRKISQETVKAA 373

Query: 449 YIYCQRIDQRDYSNNTEKTTKDELLNLLKTLDEDSKLSAKEKKKLLGQFYKC 500
            I  Q+  ++       K T+DEL+  +K      ++  +     L  F  C
Sbjct: 374 IIEEQKRSEKAV-EEAVKRTRDELIEYIKEQKRLDQVIRQRSLSSLELFLSC 424


>gi|38569484 kinesin family member 21A [Homo sapiens]
          Length = 1661

 Score = 35.8 bits (81), Expect = 0.095
 Identities = 42/192 (21%), Positives = 82/192 (42%), Gaps = 22/192 (11%)

Query: 172 EDLWENLSLKPANSPHVNISATLSPQVINEVWQEETIGRLLQLVDLPL--LDSLLKQQEA 229
           E+L +NL+   A +P+ + S+T SP +++    +ETI    +++DL    L+ L ++++ 
Sbjct: 501 ENLRKNLTRATARAPYFSGSSTFSPTILSS--DKETI----EIIDLAKKDLEKLKRKEKR 554

Query: 230 VPKIPQPKRQSTMVNSSNYLDRGILKAYSDSQEDEWLSAAIDCLEYLPDQMVVEISRSFP 289
             K    K  +T  +     ++G+ +  ++  E E      D  +   ++   E      
Sbjct: 555 KKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEEEEEDDIDGG 614

Query: 290 EQPDRTDLVKELLFDAIGRYYSSREPLLNHLSDVHNGIAELLVNGKTEIALEATQLLLKL 349
           E  D +D              S  +   N+ +D+ N   E+ +  K    LE +Q  L+ 
Sbjct: 615 ESSDESD--------------SESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQT 660

Query: 350 LDFQNREEFRRL 361
           L  Q  E+   L
Sbjct: 661 LKKQYEEKLMML 672


>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
           isoform 2 [Homo sapiens]
          Length = 2098

 Score = 35.4 bits (80), Expect = 0.12
 Identities = 37/157 (23%), Positives = 73/157 (46%), Gaps = 14/157 (8%)

Query: 38  VWSSIINTLQTQVEVKKRRHRLKRHNDCFVGSEAVDVIFSHLIQNKYFGDVDIPRAKVVR 97
           +W  I +   + +E +  R+ L+ H +C VG E V    + LI+N +       RA+ + 
Sbjct: 358 LWKKICHH-SSGMEFQDHRYWLRTHPNCIVGKELV----NWLIRNGHIA----TRAQAIA 408

Query: 98  VCQALMDYKVFEAVP--TKVFGKDKKPTFEDSSCSLYRFTTIPNQDSQLGKENKLYSPAR 155
           + QA++D +  + V    ++F +D+   +     + +  T  P+ DS    E     P+ 
Sbjct: 409 IGQAMVDGRWLDCVSHHDQLF-RDEYALYRPLQSTEFSETPSPDSDSVNSVEGH-SEPSW 466

Query: 156 YADALFKSSDIRSASLEDLWENLSLKPANSPHVNISA 192
           + D  F  SD    + E+  +NL+   + S   ++S+
Sbjct: 467 FKDIKFDDSDTEQIA-EEGDDNLANSASPSKRTSVSS 502


>gi|22749359 phosphatidylinositol-3-phosphate 5-kinase type III
           isoform 3 [Homo sapiens]
          Length = 451

 Score = 35.4 bits (80), Expect = 0.12
 Identities = 37/157 (23%), Positives = 73/157 (46%), Gaps = 14/157 (8%)

Query: 38  VWSSIINTLQTQVEVKKRRHRLKRHNDCFVGSEAVDVIFSHLIQNKYFGDVDIPRAKVVR 97
           +W  I +   + +E +  R+ L+ H +C VG E V    + LI+N +       RA+ + 
Sbjct: 261 LWKKICHH-SSGMEFQDHRYWLRTHPNCIVGKELV----NWLIRNGHIA----TRAQAIA 311

Query: 98  VCQALMDYKVFEAVP--TKVFGKDKKPTFEDSSCSLYRFTTIPNQDSQLGKENKLYSPAR 155
           + QA++D +  + V    ++F +D+   +     + +  T  P+ DS    E     P+ 
Sbjct: 312 IGQAMVDGRWLDCVSHHDQLF-RDEYALYRPLQSTEFSETPSPDSDSVNSVEGH-SEPSW 369

Query: 156 YADALFKSSDIRSASLEDLWENLSLKPANSPHVNISA 192
           + D  F  SD    + E+  +NL+   + S   ++S+
Sbjct: 370 FKDIKFDDSDTEQIA-EEGDDNLANSASPSKRTSVSS 405


>gi|189571664 DEP domain containing 6 [Homo sapiens]
          Length = 409

 Score = 33.5 bits (75), Expect = 0.47
 Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 8/66 (12%)

Query: 46  LQTQVEVKKRRHRLKRHNDCFVGSEAVDVIFSHLIQNKYFGDVDIPRAKVVRVCQALMDY 105
           L  +  +K RRH LK + +CFV  E +D     LI++K   D    R   +++ Q L D 
Sbjct: 44  LHEEKVIKDRRHHLKTYPNCFVAKELID----WLIEHKEASD----RETAIKLMQKLADR 95

Query: 106 KVFEAV 111
            +   V
Sbjct: 96  GIIHHV 101


>gi|5032031 RNA binding motif protein 5 [Homo sapiens]
          Length = 815

 Score = 33.5 bits (75), Expect = 0.47
 Identities = 54/261 (20%), Positives = 105/261 (40%), Gaps = 44/261 (16%)

Query: 145 GKENKLYSPARYADALFKSSDIRSASLEDLWENL--SLKPANSPHVNISATLSPQVINEV 202
           GKE K    ++ A  + K  +  + SL    EN   S +P NS             + E 
Sbjct: 525 GKEKKEKPKSKTAQQIAKDMERWAKSLNKQKENFKNSFQPVNS-------------LREE 571

Query: 203 WQEETIGRLLQLVDLPLLDSLLKQQEAVPKIPQPKRQSTMVNSSNYLDRGILKAYSDSQE 262
            + E+              +L ++Q+ +P++ +        +  N L RG++ AYS   +
Sbjct: 572 ERRESAAADAGFALFEKKGALAERQQLIPELVRNG------DEENPLKRGLVAAYSGDSD 625

Query: 263 DEWLSAAIDCLEYLPDQMVVEISRSFPEQPDRTDLVKELLFDAIGRYYSSREPLLNH--L 320
           +E                  E+      + ++    K++      R + +++ L+ H  L
Sbjct: 626 NE-----------------EELVERLESEEEKLADWKKMACLLCRRQFPNKDALVRHQQL 668

Query: 321 SDVHNGIAELLVNGK-TEIALEATQLLLKLLDFQNREEFRRLLYFMAVAANPSEFKLQKE 379
           SD+H    ++    + +E  LEA +L  + + +++R   RR  Y +     P E K +K+
Sbjct: 669 SDLHKQNMDIYRRSRLSEQELEALELREREMKYRDRAAERREKYGI---PEPPEPKRKKQ 725

Query: 380 SDNRMVVKRIFSKAIVDNKNL 400
            D   V     +K  +D+ N+
Sbjct: 726 FDAGTVNYEQPTKDGIDHSNI 746


>gi|208609990 nucleoporin 93kDa [Homo sapiens]
          Length = 819

 Score = 32.7 bits (73), Expect = 0.81
 Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 1/86 (1%)

Query: 415 HQKDVFKIPGTLHKIVSVKLMAIQNGRDPNRDAGYIYCQRIDQRDYSNNTEKTTKDEL-L 473
           + KD    P T +K+      A++N  DP + A Y    R D  D  +     T+D L L
Sbjct: 357 NSKDRRLSPATENKLRLHYRRALRNNTDPYKRAVYCIIGRCDVTDNQSEVADKTEDYLWL 416

Query: 474 NLLKTLDEDSKLSAKEKKKLLGQFYK 499
            L +   +D   S+ + +  L QF K
Sbjct: 417 KLNQVCFDDDGTSSPQDRLTLSQFQK 442


>gi|223718070 retinoic acid receptor, alpha isoform 4 [Homo sapiens]
          Length = 365

 Score = 30.8 bits (68), Expect = 3.1
 Identities = 13/31 (41%), Positives = 19/31 (61%)

Query: 290 EQPDRTDLVKELLFDAIGRYYSSREPLLNHL 320
           EQPDR D+++E L +A+  Y   R P   H+
Sbjct: 246 EQPDRVDMLQEPLLEALKVYVRKRRPSRPHM 276


>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
          Length = 462

 Score = 30.8 bits (68), Expect = 3.1
 Identities = 13/31 (41%), Positives = 19/31 (61%)

Query: 290 EQPDRTDLVKELLFDAIGRYYSSREPLLNHL 320
           EQPDR D+++E L +A+  Y   R P   H+
Sbjct: 343 EQPDRVDMLQEPLLEALKVYVRKRRPSRPHM 373


>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
          Length = 457

 Score = 30.8 bits (68), Expect = 3.1
 Identities = 13/31 (41%), Positives = 19/31 (61%)

Query: 290 EQPDRTDLVKELLFDAIGRYYSSREPLLNHL 320
           EQPDR D+++E L +A+  Y   R P   H+
Sbjct: 338 EQPDRVDMLQEPLLEALKVYVRKRRPSRPHM 368


>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
          Length = 462

 Score = 30.8 bits (68), Expect = 3.1
 Identities = 13/31 (41%), Positives = 19/31 (61%)

Query: 290 EQPDRTDLVKELLFDAIGRYYSSREPLLNHL 320
           EQPDR D+++E L +A+  Y   R P   H+
Sbjct: 343 EQPDRVDMLQEPLLEALKVYVRKRRPSRPHM 373


>gi|115583670 T-cell lymphoma invasion and metastasis 1 [Homo sapiens]
          Length = 1591

 Score = 30.8 bits (68), Expect = 3.1
 Identities = 21/70 (30%), Positives = 35/70 (50%), Gaps = 8/70 (11%)

Query: 290  EQPDRTDLVKELLFDAIGR--YYSSREPLLNHLSDVHNGIAELLVNGKTEIALEATQLLL 347
            E+ ++ D  K++LF   G   YY+ R  L +     H  + ++LV  KT+ A +A     
Sbjct: 1113 EKLEKVDQFKKVLFSLGGSFLYYADRFKLYSAFCASHTKVPKVLVKAKTDTAFKA----- 1167

Query: 348  KLLDFQNREE 357
              LD QN ++
Sbjct: 1168 -FLDAQNPKQ 1176


>gi|126116589 fibrocystin L [Homo sapiens]
          Length = 4243

 Score = 30.8 bits (68), Expect = 3.1
 Identities = 25/80 (31%), Positives = 38/80 (47%), Gaps = 18/80 (22%)

Query: 118 KDKKPTFEDSSCSLYRFTTIPNQDSQLGKENKLYSPARYADALFKSSDIRSASLEDLWEN 177
           K   P  E +SCSLY++  I N       E  ++ PA  ++ + +S      +L DLW  
Sbjct: 531 KVTSPCVEANSCSLYQYRLIYNM------EKTVFLPADASEFILQS------ALNDLW-- 576

Query: 178 LSLKPANSPHVNISATLSPQ 197
            S+KP     V +  T +PQ
Sbjct: 577 -SIKPDT---VQVIRTQNPQ 592


>gi|108773787 retinoblastoma 1 [Homo sapiens]
          Length = 928

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 24/97 (24%), Positives = 43/97 (44%), Gaps = 4/97 (4%)

Query: 299 KELLFDAIGRYYSSREPLLNHLSDVHNGIAELLVNGKTEIALEATQLLLKLLDFQNREEF 358
           K L  D+I  + + R P  ++L +  N I     +      +   Q L+ +L+  + +  
Sbjct: 341 KTLQTDSIDSFETQRTPRKSNLDEEVNVIPP---HTPVRTVMNTIQQLMMILNSASDQPS 397

Query: 359 RRLL-YFMAVAANPSEFKLQKESDNRMVVKRIFSKAI 394
             L+ YF     NP E  L++  D   + K  F+KA+
Sbjct: 398 ENLISYFNNCTVNPKESILKRVKDIGYIFKEKFAKAV 434


>gi|164519076 transmembrane 9 superfamily protein member 4 [Homo
           sapiens]
          Length = 642

 Score = 30.0 bits (66), Expect = 5.2
 Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 4/72 (5%)

Query: 108 FEAVPTKVFGKDKKPTFEDSSCSLYRFTTIPNQDSQLGKENKLYSPARYADALFKSSDIR 167
           FE +P  +  +D K   E SSC+L   T    Q+    KEN+LY         ++ SDI+
Sbjct: 207 FEVIPQSIRLEDLKAD-EKSSCTLPEGTNSSPQEIDPTKENQLYFT---YSVHWEESDIK 262

Query: 168 SASLEDLWENLS 179
            AS  D +  +S
Sbjct: 263 WASRWDTYLTMS 274


>gi|34452709 bromodomain containing 8 isoform 3 [Homo sapiens]
          Length = 757

 Score = 29.6 bits (65), Expect = 6.8
 Identities = 20/72 (27%), Positives = 39/72 (54%), Gaps = 4/72 (5%)

Query: 179 SLKPANSPHVNISATLSPQVINEVWQEETIGRLLQLVDLPLLDSLLKQQEAVPKIPQPKR 238
           +L P ++P   + A ++P V ++  Q++ +G+       PLL  LLK+   +P  P+   
Sbjct: 94  TLPPGSAP---LEAPMTP-VTDDSPQKKMLGQKATPPPSPLLSELLKKGSLLPTSPRLVN 149

Query: 239 QSTMVNSSNYLD 250
           +S M  +S +L+
Sbjct: 150 ESEMAVASGHLN 161


>gi|34452705 bromodomain containing 8 isoform 1 [Homo sapiens]
          Length = 951

 Score = 29.6 bits (65), Expect = 6.8
 Identities = 20/72 (27%), Positives = 39/72 (54%), Gaps = 4/72 (5%)

Query: 179 SLKPANSPHVNISATLSPQVINEVWQEETIGRLLQLVDLPLLDSLLKQQEAVPKIPQPKR 238
           +L P ++P   + A ++P V ++  Q++ +G+       PLL  LLK+   +P  P+   
Sbjct: 234 TLPPGSAP---LEAPMTP-VTDDSPQKKMLGQKATPPPSPLLSELLKKGSLLPTSPRLVN 289

Query: 239 QSTMVNSSNYLD 250
           +S M  +S +L+
Sbjct: 290 ESEMAVASGHLN 301


>gi|214010216 SMC6 protein [Homo sapiens]
          Length = 1091

 Score = 29.6 bits (65), Expect = 6.8
 Identities = 48/213 (22%), Positives = 85/213 (39%), Gaps = 19/213 (8%)

Query: 307 GRYYSSREPLLNHLS-DVHNGIAELL--VNGKTEIALEATQLLLKL-LDFQNREEF--RR 360
           GRYYSS       LS DV + I++L   V  KT   L   Q L  L  D ++ EE   R 
Sbjct: 647 GRYYSSENTRPKFLSRDVDSEISDLENEVENKTAQILNLQQHLSALEKDIKHNEELLKRC 706

Query: 361 LLYF----MAVAANPSEFKLQKESDNRMVVKRIFSKAIVDNKNLSKGKTDLLVLFL---- 412
            L++    M +  N SE +   E +N    + +    + D    +K K  ++   +    
Sbjct: 707 QLHYKELKMKIRKNISEIR---ELENIEEHQSVDIATLEDEAQENKSKMKMVEEHMEQQK 763

Query: 413 --MDHQKDVFKIPGTLHKIVSVKLMAIQNGRDPNRDAGYIYCQRIDQRDYSNNTEKTTKD 470
             M+H K +       +  +  K+  +    DP +D   +    +D +       +  + 
Sbjct: 764 ENMEHLKSLKIEAENKYDAIKFKINQLSELADPLKDELNLADSEVDNQKRGKRHYEEKQK 823

Query: 471 ELLNLLKTLDEDSKLSAKEKKKLLGQFYKCHPD 503
           E L+ L     +  +  KE ++ + Q  +  P+
Sbjct: 824 EHLDTLNKKKRELDMKEKELEEKMSQARQICPE 856


>gi|13375848 SMC6 protein [Homo sapiens]
          Length = 1091

 Score = 29.6 bits (65), Expect = 6.8
 Identities = 48/213 (22%), Positives = 85/213 (39%), Gaps = 19/213 (8%)

Query: 307 GRYYSSREPLLNHLS-DVHNGIAELL--VNGKTEIALEATQLLLKL-LDFQNREEF--RR 360
           GRYYSS       LS DV + I++L   V  KT   L   Q L  L  D ++ EE   R 
Sbjct: 647 GRYYSSENTRPKFLSRDVDSEISDLENEVENKTAQILNLQQHLSALEKDIKHNEELLKRC 706

Query: 361 LLYF----MAVAANPSEFKLQKESDNRMVVKRIFSKAIVDNKNLSKGKTDLLVLFL---- 412
            L++    M +  N SE +   E +N    + +    + D    +K K  ++   +    
Sbjct: 707 QLHYKELKMKIRKNISEIR---ELENIEEHQSVDIATLEDEAQENKSKMKMVEEHMEQQK 763

Query: 413 --MDHQKDVFKIPGTLHKIVSVKLMAIQNGRDPNRDAGYIYCQRIDQRDYSNNTEKTTKD 470
             M+H K +       +  +  K+  +    DP +D   +    +D +       +  + 
Sbjct: 764 ENMEHLKSLKIEAENKYDAIKFKINQLSELADPLKDELNLADSEVDNQKRGKRHYEEKQK 823

Query: 471 ELLNLLKTLDEDSKLSAKEKKKLLGQFYKCHPD 503
           E L+ L     +  +  KE ++ + Q  +  P+
Sbjct: 824 EHLDTLNKKKRELDMKEKELEEKMSQARQICPE 856


>gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]
          Length = 1528

 Score = 29.3 bits (64), Expect = 8.9
 Identities = 44/177 (24%), Positives = 73/177 (41%), Gaps = 43/177 (24%)

Query: 269  AIDCLEYLPDQMVVEISRSFPEQPDRTDLVKELLFDAIGRYYSSREPLL-NHLSDVHNGI 327
            AIDC+ Y                 D  D++K+   D         EPL+ N LS+    I
Sbjct: 1132 AIDCVNYEGQSAY-----------DVADMLKQYFRDL-------PEPLMTNKLSETFLQI 1173

Query: 328  AELLVNGKTEIALEATQLLLKLLDFQNREEFRRLLYF-----------------MAVAAN 370
             + +   +    L+A +  + LL  +NRE  + LLYF                 +AV   
Sbjct: 1174 YQYVPKDQR---LQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLA 1230

Query: 371  PSEF---KLQKESDNRMVVKRIFSKAIVDNKNLSKGKTDLLVL-FLMDHQKDVFKIP 423
            PS F    L++E+ +  V++R  S    D K+L++       L  ++   K +F++P
Sbjct: 1231 PSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVP 1287


>gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens]
          Length = 1091

 Score = 29.3 bits (64), Expect = 8.9
 Identities = 44/177 (24%), Positives = 73/177 (41%), Gaps = 43/177 (24%)

Query: 269 AIDCLEYLPDQMVVEISRSFPEQPDRTDLVKELLFDAIGRYYSSREPLL-NHLSDVHNGI 327
           AIDC+ Y                 D  D++K+   D         EPL+ N LS+    I
Sbjct: 695 AIDCVNYEGQSAY-----------DVADMLKQYFRDL-------PEPLMTNKLSETFLQI 736

Query: 328 AELLVNGKTEIALEATQLLLKLLDFQNREEFRRLLYF-----------------MAVAAN 370
            + +   +    L+A +  + LL  +NRE  + LLYF                 +AV   
Sbjct: 737 YQYVPKDQR---LQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLA 793

Query: 371 PSEF---KLQKESDNRMVVKRIFSKAIVDNKNLSKGKTDLLVL-FLMDHQKDVFKIP 423
           PS F    L++E+ +  V++R  S    D K+L++       L  ++   K +F++P
Sbjct: 794 PSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVP 850


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,604,791
Number of Sequences: 37866
Number of extensions: 795591
Number of successful extensions: 2228
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 2202
Number of HSP's gapped (non-prelim): 34
length of query: 511
length of database: 18,247,518
effective HSP length: 107
effective length of query: 404
effective length of database: 14,195,856
effective search space: 5735125824
effective search space used: 5735125824
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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