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Search of human proteins with 116256336
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116256336 SEC31 homolog A isoform 4 [Homo sapiens]
(1106 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116256336 SEC31 homolog A isoform 4 [Homo sapiens] 2240 0.0
gi|116256340 SEC31 homolog A isoform 3 [Homo sapiens] 1874 0.0
gi|116256338 SEC31 homolog A isoform 1 [Homo sapiens] 1801 0.0
gi|41349439 SEC31 homolog A isoform 1 [Homo sapiens] 1801 0.0
gi|41349441 SEC31 homolog A isoform 2 [Homo sapiens] 1710 0.0
gi|14149696 SEC31 homolog B [Homo sapiens] 1022 0.0
gi|58331266 WD repeat domain 59 [Homo sapiens] 61 5e-09
gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sa... 59 3e-08
gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sa... 59 3e-08
gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapi... 59 3e-08
gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo ... 59 3e-08
gi|217416452 dynein, axonemal, intermediate polypeptide 2 [Homo ... 57 1e-07
gi|4506439 retinoblastoma binding protein 7 [Homo sapiens] 55 4e-07
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 54 6e-07
gi|217330644 WD repeat domain 12 protein [Homo sapiens] 54 1e-06
gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens] 53 2e-06
gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens] 53 2e-06
gi|13129110 WD repeat domain 77 [Homo sapiens] 53 2e-06
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 53 2e-06
gi|157739942 gemin 5 [Homo sapiens] 52 3e-06
gi|118402582 cell division cycle 20 [Homo sapiens] 52 4e-06
gi|4758178 dynein, cytoplasmic 1, intermediate chain 1 isoform a... 51 5e-06
gi|207113124 dynein, cytoplasmic 1, intermediate chain 1 isoform... 51 5e-06
gi|207113122 dynein, cytoplasmic 1, intermediate chain 1 isoform... 51 5e-06
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 51 5e-06
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 51 5e-06
gi|8923881 WD SOCS-box protein 2 [Homo sapiens] 51 5e-06
gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] 51 7e-06
gi|213021188 transducin beta-like 1X isoform b [Homo sapiens] 51 7e-06
gi|213021186 transducin beta-like 1X isoform a [Homo sapiens] 51 7e-06
>gi|116256336 SEC31 homolog A isoform 4 [Homo sapiens]
Length = 1106
Score = 2240 bits (5805), Expect = 0.0
Identities = 1106/1106 (100%), Positives = 1106/1106 (100%)
Query: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60
MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC
Sbjct: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60
Query: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120
ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK
Sbjct: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120
Query: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 180
HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV
Sbjct: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 180
Query: 181 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 240
QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV
Sbjct: 181 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 240
Query: 241 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 300
IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP
Sbjct: 241 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 300
Query: 301 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 360
TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG
Sbjct: 301 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 360
Query: 361 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 420
TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ
Sbjct: 361 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 420
Query: 421 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 480
QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN
Sbjct: 421 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 480
Query: 481 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL 540
FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL
Sbjct: 481 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL 540
Query: 541 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 600
GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII
Sbjct: 541 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 600
Query: 601 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 660
LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA
Sbjct: 601 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 660
Query: 661 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 720
KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL
Sbjct: 661 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 720
Query: 721 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 780
IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM
Sbjct: 721 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 780
Query: 781 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 840
QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP
Sbjct: 781 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 840
Query: 841 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQRPQNGWNDPPALNRVPKKKKMPENF 900
PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQRPQNGWNDPPALNRVPKKKKMPENF
Sbjct: 841 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQRPQNGWNDPPALNRVPKKKKMPENF 900
Query: 901 MPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTG 960
MPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTG
Sbjct: 901 MPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTG 960
Query: 961 MPPSFSKPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSA 1020
MPPSFSKPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSA
Sbjct: 961 MPPSFSKPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSA 1020
Query: 1021 TDPQTKRKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVS 1080
TDPQTKRKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVS
Sbjct: 1021 TDPQTKRKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVS 1080
Query: 1081 TSNFSETSAFMPVLKVVLTQANKLGV 1106
TSNFSETSAFMPVLKVVLTQANKLGV
Sbjct: 1081 TSNFSETSAFMPVLKVVLTQANKLGV 1106
>gi|116256340 SEC31 homolog A isoform 3 [Homo sapiens]
Length = 1205
Score = 1874 bits (4854), Expect = 0.0
Identities = 985/1207 (81%), Positives = 1003/1207 (83%), Gaps = 103/1207 (8%)
Query: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60
MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC
Sbjct: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60
Query: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120
ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK
Sbjct: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120
Query: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 180
HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV
Sbjct: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 180
Query: 181 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 240
QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV
Sbjct: 181 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 240
Query: 241 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 300
IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP
Sbjct: 241 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 300
Query: 301 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 360
TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG
Sbjct: 301 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 360
Query: 361 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 420
TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ
Sbjct: 361 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 420
Query: 421 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 480
QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN
Sbjct: 421 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 480
Query: 481 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL 540
FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL
Sbjct: 481 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL 540
Query: 541 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 600
GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII
Sbjct: 541 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 600
Query: 601 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 660
LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA
Sbjct: 601 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 660
Query: 661 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 720
KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL
Sbjct: 661 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 720
Query: 721 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 780
IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM
Sbjct: 721 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 780
Query: 781 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 840
QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP
Sbjct: 781 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 840
Query: 841 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQRPQNGWNDP-----PALNRVPKKKK 895
PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQ Q P A+ R P++
Sbjct: 841 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYR-PQQPV 899
Query: 896 MP--ENFMPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHG-- 951
P N P P S + G Q Q Q S+P S +SFP P G HG
Sbjct: 900 APPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTS-SPATSFPPPPSSGASFQHGGP 958
Query: 952 --------VQQPLGQTG-------------------MPPSFSKPNIEGAP-----GAPIG 979
P G TG MP +F P +P G P
Sbjct: 959 GAPPSSSAYALPPGTTGPQNGWNDPPALNRVPKKKKMPENFMPPVPITSPIMNPLGDPQS 1018
Query: 980 NTFQHVQSLPTKKITKKPIPDEHL---------------------ILKTTFE-------- 1010
Q S P ++ P HL K E
Sbjct: 1019 QMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFSKPNIEGAPGAPIG 1078
Query: 1011 DLIQRCLSSATDPQTKRKLDDASKRLEFLYDKLREQTL---------------------- 1048
+ Q S T TK+ + D L+ ++ L ++ L
Sbjct: 1079 NTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTKRKLDDASKRLEFL 1138
Query: 1049 ---------SPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSETSAFMPVLKVVLT 1099
SPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSETSAFMPVLKVVLT
Sbjct: 1139 YDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSETSAFMPVLKVVLT 1198
Query: 1100 QANKLGV 1106
QANKLGV
Sbjct: 1199 QANKLGV 1205
>gi|116256338 SEC31 homolog A isoform 1 [Homo sapiens]
Length = 1220
Score = 1801 bits (4665), Expect = 0.0
Identities = 957/1222 (78%), Positives = 983/1222 (80%), Gaps = 118/1222 (9%)
Query: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60
MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC
Sbjct: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60
Query: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120
ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK
Sbjct: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120
Query: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 180
HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV
Sbjct: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 180
Query: 181 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 240
QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV
Sbjct: 181 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 240
Query: 241 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 300
IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP
Sbjct: 241 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 300
Query: 301 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 360
TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG
Sbjct: 301 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 360
Query: 361 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 420
TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ
Sbjct: 361 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 420
Query: 421 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 480
QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN
Sbjct: 421 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 480
Query: 481 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL 540
FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL
Sbjct: 481 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL 540
Query: 541 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 600
GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII
Sbjct: 541 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 600
Query: 601 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 660
LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA
Sbjct: 601 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 660
Query: 661 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 720
KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL
Sbjct: 661 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 720
Query: 721 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 780
IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM
Sbjct: 721 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 780
Query: 781 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 840
QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP
Sbjct: 781 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 840
Query: 841 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQRPQNGWNDP-----PALNRVPKKKK 895
PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQ Q P A+ R P++
Sbjct: 841 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYR-PQQPV 899
Query: 896 MP--ENFMPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHG-- 951
P N P P S + G Q Q Q S+P S +SFP P G HG
Sbjct: 900 APPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTS-SPATSFPPPPSSGASFQHGGP 958
Query: 952 --------VQQPLGQTG----------------------------------MPPSFSKPN 969
P G TG MP +F P
Sbjct: 959 GAPPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPV 1018
Query: 970 IEGAP-----GAPIGNTFQHVQSLPTKKITKKPIPDEHL--------------------- 1003
+P G P Q S P ++ P HL
Sbjct: 1019 PITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPS 1078
Query: 1004 ILKTTFE--------DLIQRCLSSATDPQTKRKLDDASKRLEFLYDKLREQTLS----PT 1051
K E + Q S T TK+ + D L+ ++ L ++ LS P
Sbjct: 1079 FSKPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQ 1138
Query: 1052 ITSGLHNIARSIE-----------TRNYSEGLTMHTHIVSTSNFS--------------- 1085
L + ++ +E + + GL + T N+S
Sbjct: 1139 TKRKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNF 1198
Query: 1086 -ETSAFMPVLKVVLTQANKLGV 1106
ETSAFMPVLKVVLTQANKLGV
Sbjct: 1199 SETSAFMPVLKVVLTQANKLGV 1220
>gi|41349439 SEC31 homolog A isoform 1 [Homo sapiens]
Length = 1220
Score = 1801 bits (4665), Expect = 0.0
Identities = 957/1222 (78%), Positives = 983/1222 (80%), Gaps = 118/1222 (9%)
Query: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60
MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC
Sbjct: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60
Query: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120
ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK
Sbjct: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120
Query: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 180
HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV
Sbjct: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 180
Query: 181 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 240
QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV
Sbjct: 181 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 240
Query: 241 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 300
IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP
Sbjct: 241 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 300
Query: 301 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 360
TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG
Sbjct: 301 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 360
Query: 361 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 420
TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ
Sbjct: 361 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 420
Query: 421 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 480
QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN
Sbjct: 421 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 480
Query: 481 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL 540
FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL
Sbjct: 481 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL 540
Query: 541 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 600
GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII
Sbjct: 541 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 600
Query: 601 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 660
LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA
Sbjct: 601 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 660
Query: 661 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 720
KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL
Sbjct: 661 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 720
Query: 721 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 780
IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM
Sbjct: 721 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 780
Query: 781 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 840
QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP
Sbjct: 781 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 840
Query: 841 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQRPQNGWNDP-----PALNRVPKKKK 895
PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQ Q P A+ R P++
Sbjct: 841 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYR-PQQPV 899
Query: 896 MP--ENFMPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHG-- 951
P N P P S + G Q Q Q S+P S +SFP P G HG
Sbjct: 900 APPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTS-SPATSFPPPPSSGASFQHGGP 958
Query: 952 --------VQQPLGQTG----------------------------------MPPSFSKPN 969
P G TG MP +F P
Sbjct: 959 GAPPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPV 1018
Query: 970 IEGAP-----GAPIGNTFQHVQSLPTKKITKKPIPDEHL--------------------- 1003
+P G P Q S P ++ P HL
Sbjct: 1019 PITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPS 1078
Query: 1004 ILKTTFE--------DLIQRCLSSATDPQTKRKLDDASKRLEFLYDKLREQTLS----PT 1051
K E + Q S T TK+ + D L+ ++ L ++ LS P
Sbjct: 1079 FSKPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQ 1138
Query: 1052 ITSGLHNIARSIE-----------TRNYSEGLTMHTHIVSTSNFS--------------- 1085
L + ++ +E + + GL + T N+S
Sbjct: 1139 TKRKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNF 1198
Query: 1086 -ETSAFMPVLKVVLTQANKLGV 1106
ETSAFMPVLKVVLTQANKLGV
Sbjct: 1199 SETSAFMPVLKVVLTQANKLGV 1220
>gi|41349441 SEC31 homolog A isoform 2 [Homo sapiens]
Length = 1181
Score = 1710 bits (4428), Expect = 0.0
Identities = 918/1222 (75%), Positives = 944/1222 (77%), Gaps = 157/1222 (12%)
Query: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60
MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC
Sbjct: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60
Query: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120
ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK
Sbjct: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120
Query: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 180
HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV
Sbjct: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 180
Query: 181 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 240
QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV
Sbjct: 181 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 240
Query: 241 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 300
IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP
Sbjct: 241 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 300
Query: 301 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 360
TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG
Sbjct: 301 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 360
Query: 361 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 420
TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ
Sbjct: 361 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 420
Query: 421 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 480
QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN
Sbjct: 421 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 480
Query: 481 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL 540
FEDDSRGKYLELLGYRKEDLGKK
Sbjct: 481 FEDDSRGKYLELLGYRKEDLGKK------------------------------------- 503
Query: 541 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 600
HIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII
Sbjct: 504 --HIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 561
Query: 601 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 660
LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA
Sbjct: 562 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 621
Query: 661 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 720
KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL
Sbjct: 622 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 681
Query: 721 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 780
IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM
Sbjct: 682 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 741
Query: 781 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 840
QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP
Sbjct: 742 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 801
Query: 841 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQRPQNGWNDP-----PALNRVPKKKK 895
PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQ Q P A+ R P++
Sbjct: 802 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYR-PQQPV 860
Query: 896 MP--ENFMPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHG-- 951
P N P P S + G Q Q Q S+P S +SFP P G HG
Sbjct: 861 APPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTS-SPATSFPPPPSSGASFQHGGP 919
Query: 952 --------VQQPLGQTG----------------------------------MPPSFSKPN 969
P G TG MP +F P
Sbjct: 920 GAPPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPV 979
Query: 970 IEGAP-----GAPIGNTFQHVQSLPTKKITKKPIPDEHL--------------------- 1003
+P G P Q S P ++ P HL
Sbjct: 980 PITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPS 1039
Query: 1004 ILKTTFE--------DLIQRCLSSATDPQTKRKLDDASKRLEFLYDKLREQTLS----PT 1051
K E + Q S T TK+ + D L+ ++ L ++ LS P
Sbjct: 1040 FSKPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQ 1099
Query: 1052 ITSGLHNIARSIE-----------TRNYSEGLTMHTHIVSTSNFS--------------- 1085
L + ++ +E + + GL + T N+S
Sbjct: 1100 TKRKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNF 1159
Query: 1086 -ETSAFMPVLKVVLTQANKLGV 1106
ETSAFMPVLKVVLTQANKLGV
Sbjct: 1160 SETSAFMPVLKVVLTQANKLGV 1181
>gi|14149696 SEC31 homolog B [Homo sapiens]
Length = 1179
Score = 1022 bits (2643), Expect = 0.0
Identities = 564/1198 (47%), Positives = 752/1198 (62%), Gaps = 115/1198 (9%)
Query: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60
MKLKE++R A+QAWSPA +P+YLATGTSAQQLD++FSTN +LEIFE+D DPSLD+K
Sbjct: 1 MKLKELERPAVQAWSPASQYPLYLATGTSAQQLDSSFSTNGTLEIFEVDFRDPSLDLKHR 60
Query: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120
S+ R+HKL+WG + + SGV++ GG+NG +ILY+ + I++ KE VIAQ K
Sbjct: 61 GVLSALSRFHKLVWGSFGSGLL-ESSGVIVGGGDNGMLILYNVTHILSSGKEPVIAQKQK 119
Query: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQ-PPEDISCIAWNRQ 179
HTG VRALD+N FQ NL+ASGA++SEI+IWDLNN PMT G+K+Q PPEDI ++WNRQ
Sbjct: 120 HTGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLNVPMTLGSKSQQPPEDIKALSWNRQ 179
Query: 180 VQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLP 239
QHIL+SA PSG+A VWDLRKNEPIIKVSDHSNRMHCSGLAWHPD+ATQ+VL SEDDRLP
Sbjct: 180 AQHILSSAHPSGKAVVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDIATQLVLCSEDDRLP 239
Query: 240 VIQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYEL 299
VIQ+WDLRFASSPL+VLE+H+RGIL+++WS AD ELLL+ KD++ILC N + EV+Y+L
Sbjct: 240 VIQLWDLRFASSPLKVLESHSRGILSVSWSQADAELLLTSAKDSQILCRNLGSSEVVYKL 299
Query: 300 PTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPF 359
PT + WCFD+QWCPR+P+V SAASF+G IS+YS+MG S + +Q DK+SSSF
Sbjct: 300 PTQSSWCFDVQWCPRDPSVFSAASFNGWISLYSVMGRSWEVQHMRQADKISSSFSK---- 355
Query: 360 GTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAE 419
GQPLPPLQ+P+Q AQ ++ PLKKPPKWIRRP G SF+FGGKLVTF P+H
Sbjct: 356 --GQPLPPLQVPEQVAQAPLIPPLKKPPKWIRRPTGVSFAFGGKLVTFGLPSTPAH--LV 411
Query: 420 QQQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKV 479
Q VFISQV TE EFL RS +LQ+A+ S +NYCQ K + + EK +W FLKV
Sbjct: 412 PQPCPRLVFISQVTTESEFLMRSAELQEALGSGNLLNYCQNKSQQALLQSEKMLWQFLKV 471
Query: 480 NFEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQL 539
E DSR K+L+LLGY K++L KK+A L G + + SD +++ ++
Sbjct: 472 TLEQDSRMKFLKLLGYSKDELQKKVATWLKSDVGLGESPQPKGNDLNSDRQQAFCSQ--- 528
Query: 540 LGEHIKEEKEES-----EFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNR 594
+H +E S E +P + + I ++ DIDGL++QALL G AV+LCL + R
Sbjct: 529 ASKHTTKEASASSAFFDELVPQNMTPWEIPITKDIDGLLSQALLLGELGPAVELCLKEER 588
Query: 595 MADAIILAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALA 654
ADAIILA AGG +LL +TQ++Y AK ++KI+ L+ VV KNWK++V +C LKNWREALA
Sbjct: 589 FADAIILAQAGGTDLLKQTQERYLAKKKTKISSLLACVVQKNWKDVVCTCSLKNWREALA 648
Query: 655 AVLTYAKPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHP 714
+LTY+ ++F LCD+LGTR+E EG L ++A LCY+C+G+VE+LV CW K P
Sbjct: 649 LLLTYSGTEKFPELCDMLGTRMEQEGSRALTSEARLCYVCSGSVERLVECWAKCHQALSP 708
Query: 715 LSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNT 774
++LQDL+EKV++L ++++ + + G +++QYANLLAAQGS+A A++FLP +
Sbjct: 709 MALQDLMEKVMVLNRSLEQLRGPHGVSPGPATTYRVTQYANLLAAQGSLATAMSFLPRDC 768
Query: 775 NQPNIMQLRDRLCRAQGEPVAGHESPKIPYEK---------QQLPKGRPGPVAGHH---- 821
QP + QLRDRL AQG V G +SP P+ + ++ R G H
Sbjct: 769 AQPPVQQLRDRLFHAQGSAVLGQQSPPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTP 828
Query: 822 -QMPRVQTQQYYP----HGENPPPPGFIMHGNVN------PNAAGQLPTSPGHMHTQVPP 870
PRV T Q P +P P N++ P A LP SPG P
Sbjct: 829 SPRPRVFTPQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQP 888
Query: 871 ---------YPQPQRPQNGWNDP--PALNRVPKKKKMPENFMPPVPITSPI--MNPLGDP 917
P P W P P P + +P P P+ + PLG
Sbjct: 889 QLLGGQRVQVPNPVGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLG-- 946
Query: 918 QSQMLQQQPSAPVPLSSQSSFPQPHLPGGQ--------PFHGVQQP-------------- 955
+M+ P+ P +SFP P+LPG P G+ P
Sbjct: 947 PGRMVSHTPAPP------ASFPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAPAP 1000
Query: 956 --------LGQTGMPPS-------FSKPNIEG--------------APGAPIGNTFQHVQ 986
L +T MPP+ P ++G PG P G +Q
Sbjct: 1001 RGNLQRNKLPETFMPPAPITAPVMSLTPELQGILPSQPPVSSVSHAPPGVP-GELSLQLQ 1059
Query: 987 SLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTKRKLDDASKRLEFLYDKLREQ 1046
LP +K+ +K +P EH LK++FE L+QRC SATD +TKRKL++A++RLE+LY+KL E
Sbjct: 1060 HLPPEKMERKELPPEHQSLKSSFEALLQRCSLSATDLKTKRKLEEAAQRLEYLYEKLCEG 1119
Query: 1047 TLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSETSAFMPVLKVVLTQANKL 1104
TLSP + +GLH +AR ++ ++ +GL +H + S+FSE S+FMP+LK VL A+KL
Sbjct: 1120 TLSPHVVAGLHEVARCVDAGSFEQGLAVHAQVAGCSSFSEVSSFMPILKAVLIIAHKL 1177
>gi|58331266 WD repeat domain 59 [Homo sapiens]
Length = 974
Score = 61.2 bits (147), Expect = 5e-09
Identities = 38/137 (27%), Positives = 69/137 (50%), Gaps = 10/137 (7%)
Query: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 180
HT + LD +F+ +L+ + + ++ IYIWD+ + P S + WN++
Sbjct: 104 HTRVISDLDWAVFEPDLLVTSSVDTYIYIWDIKD---TRKPTVALSAVAGASQVKWNKKN 160
Query: 181 QHILASASPSGRATVWDLRKNEPIIK-VSDHSNRMHCSGLAWHPDVATQMVLASEDDRLP 239
+ LA+ S G +WD RK ++ ++ H +++H GL WHPD + +S+D+
Sbjct: 161 ANCLAT-SHDGDVRIWDKRKPSTAVEYLAAHLSKIH--GLDWHPDSEHILATSSQDNS-- 215
Query: 240 VIQMWDLRFASSPLRVL 256
++ WD R L +L
Sbjct: 216 -VKFWDYRQPRKYLNIL 231
Score = 30.8 bits (68), Expect = 7.4
Identities = 29/154 (18%), Positives = 59/154 (38%), Gaps = 11/154 (7%)
Query: 133 FQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGR 192
F AS ++Y W + T T+ D+ W +L ++S
Sbjct: 73 FAHYFAASSNQRVDLYKWKDGSGEVGTTLQGHTRVISDLD---WAVFEPDLLVTSSVDTY 129
Query: 193 ATVWDLRKN-EPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASS 251
+WD++ +P + +S + S + W+ A + + + D +++WD R S+
Sbjct: 130 IYIWDIKDTRKPTVALSAVAG---ASQVKWNKKNANCLATSHDGD----VRIWDKRKPST 182
Query: 252 PLRVLENHARGILAIAWSMADPELLLSCGKDAKI 285
+ L H I + W +L + +D +
Sbjct: 183 AVEYLAAHLSKIHGLDWHPDSEHILATSSQDNSV 216
>gi|207029439 retinoblastoma binding protein 4 isoform c [Homo
sapiens]
Length = 390
Score = 58.9 bits (141), Expect = 3e-08
Identities = 52/221 (23%), Positives = 95/221 (42%), Gaps = 20/221 (9%)
Query: 77 YKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQN--DKHTGPVRALDVNIFQ 134
Y + ++SG L++ ++ I L+D S + K VV A+ HT V + ++
Sbjct: 146 YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGK-VVDAKTIFTGHTAVVEDVSWHLLH 204
Query: 135 TNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRAT 194
+L S A++ ++ IWD + T + +++C+++N + ILA+ S
Sbjct: 205 ESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVA 264
Query: 195 VWDLRKNEPIIKVSDHSNRMHCSGL---AWHPDVATQMVLASEDDRLPVIQMWDLRFASS 251
+WDLR +K+ HS H + W P T + + D RL V + + S
Sbjct: 265 LWDLRN----LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQS 320
Query: 252 P----------LRVLENHARGILAIAWSMADPELLLSCGKD 282
P L + H I +W+ +P ++ S +D
Sbjct: 321 PEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSED 361
Score = 52.8 bits (125), Expect = 2e-06
Identities = 56/249 (22%), Positives = 98/249 (39%), Gaps = 45/249 (18%)
Query: 140 SGANESEIYIWDLNNFATPM---TPGAKT------QPPEDISCIAWNRQVQHILASASPS 190
S +++ I +WD++ A P AKT ED+S W+ + + S +
Sbjct: 160 SASDDHTICLWDIS--AVPKEGKVVDAKTIFTGHTAVVEDVS---WHLLHESLFGSVADD 214
Query: 191 GRATVWDLRKN---EPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLR 247
+ +WD R N +P V H+ ++C L+++P + S D + +WDLR
Sbjct: 215 QKLMIWDTRSNNTSKPSHSVDAHTAEVNC--LSFNPYSEFILATGSADK---TVALWDLR 269
Query: 248 FASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILC--------------SNPNTG 293
L E+H I + WS + +L S G D ++ +
Sbjct: 270 NLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPP 329
Query: 294 EVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSF 353
E+L+ +T D W P P V+ + S D + V+ + + +
Sbjct: 330 ELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQM---------AENIYNDEDPE 380
Query: 354 GNLDPFGTG 362
G++DP G G
Sbjct: 381 GSVDPEGQG 389
>gi|207029415 retinoblastoma binding protein 4 isoform b [Homo
sapiens]
Length = 424
Score = 58.9 bits (141), Expect = 3e-08
Identities = 52/221 (23%), Positives = 95/221 (42%), Gaps = 20/221 (9%)
Query: 77 YKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQN--DKHTGPVRALDVNIFQ 134
Y + ++SG L++ ++ I L+D S + K VV A+ HT V + ++
Sbjct: 180 YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGK-VVDAKTIFTGHTAVVEDVSWHLLH 238
Query: 135 TNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRAT 194
+L S A++ ++ IWD + T + +++C+++N + ILA+ S
Sbjct: 239 ESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVA 298
Query: 195 VWDLRKNEPIIKVSDHSNRMHCSGL---AWHPDVATQMVLASEDDRLPVIQMWDLRFASS 251
+WDLR +K+ HS H + W P T + + D RL V + + S
Sbjct: 299 LWDLRN----LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQS 354
Query: 252 P----------LRVLENHARGILAIAWSMADPELLLSCGKD 282
P L + H I +W+ +P ++ S +D
Sbjct: 355 PEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSED 395
Score = 52.8 bits (125), Expect = 2e-06
Identities = 56/249 (22%), Positives = 98/249 (39%), Gaps = 45/249 (18%)
Query: 140 SGANESEIYIWDLNNFATPM---TPGAKT------QPPEDISCIAWNRQVQHILASASPS 190
S +++ I +WD++ A P AKT ED+S W+ + + S +
Sbjct: 194 SASDDHTICLWDIS--AVPKEGKVVDAKTIFTGHTAVVEDVS---WHLLHESLFGSVADD 248
Query: 191 GRATVWDLRKN---EPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLR 247
+ +WD R N +P V H+ ++C L+++P + S D + +WDLR
Sbjct: 249 QKLMIWDTRSNNTSKPSHSVDAHTAEVNC--LSFNPYSEFILATGSADK---TVALWDLR 303
Query: 248 FASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILC--------------SNPNTG 293
L E+H I + WS + +L S G D ++ +
Sbjct: 304 NLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPP 363
Query: 294 EVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSF 353
E+L+ +T D W P P V+ + S D + V+ + + +
Sbjct: 364 ELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQM---------AENIYNDEDPE 414
Query: 354 GNLDPFGTG 362
G++DP G G
Sbjct: 415 GSVDPEGQG 423
>gi|5032027 retinoblastoma binding protein 4 isoform a [Homo
sapiens]
Length = 425
Score = 58.9 bits (141), Expect = 3e-08
Identities = 52/221 (23%), Positives = 95/221 (42%), Gaps = 20/221 (9%)
Query: 77 YKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQN--DKHTGPVRALDVNIFQ 134
Y + ++SG L++ ++ I L+D S + K VV A+ HT V + ++
Sbjct: 181 YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGK-VVDAKTIFTGHTAVVEDVSWHLLH 239
Query: 135 TNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRAT 194
+L S A++ ++ IWD + T + +++C+++N + ILA+ S
Sbjct: 240 ESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVA 299
Query: 195 VWDLRKNEPIIKVSDHSNRMHCSGL---AWHPDVATQMVLASEDDRLPVIQMWDLRFASS 251
+WDLR +K+ HS H + W P T + + D RL V + + S
Sbjct: 300 LWDLRN----LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQS 355
Query: 252 P----------LRVLENHARGILAIAWSMADPELLLSCGKD 282
P L + H I +W+ +P ++ S +D
Sbjct: 356 PEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSED 396
Score = 52.8 bits (125), Expect = 2e-06
Identities = 56/249 (22%), Positives = 98/249 (39%), Gaps = 45/249 (18%)
Query: 140 SGANESEIYIWDLNNFATPM---TPGAKT------QPPEDISCIAWNRQVQHILASASPS 190
S +++ I +WD++ A P AKT ED+S W+ + + S +
Sbjct: 195 SASDDHTICLWDIS--AVPKEGKVVDAKTIFTGHTAVVEDVS---WHLLHESLFGSVADD 249
Query: 191 GRATVWDLRKN---EPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLR 247
+ +WD R N +P V H+ ++C L+++P + S D + +WDLR
Sbjct: 250 QKLMIWDTRSNNTSKPSHSVDAHTAEVNC--LSFNPYSEFILATGSADK---TVALWDLR 304
Query: 248 FASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILC--------------SNPNTG 293
L E+H I + WS + +L S G D ++ +
Sbjct: 305 NLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPP 364
Query: 294 EVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSF 353
E+L+ +T D W P P V+ + S D + V+ + + +
Sbjct: 365 ELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQM---------AENIYNDEDPE 415
Query: 354 GNLDPFGTG 362
G++DP G G
Sbjct: 416 GSVDPEGQG 424
>gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo
sapiens]
Length = 421
Score = 58.5 bits (140), Expect = 3e-08
Identities = 51/202 (25%), Positives = 96/202 (47%), Gaps = 18/202 (8%)
Query: 143 NESEIYIWDLNNFATPMTPGAKTQPPEDISC--IAWNR----QVQHILASASPSGRATVW 196
N+ +I D + + G+ P + C I W+R Q Q +LA+ +GR +W
Sbjct: 97 NKPREHIIDCGDIVWSLAFGSSV-PEKQSRCVNIEWHRFRFGQDQLLLATGLNNGRIKIW 155
Query: 197 DLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVL 256
D+ + ++ + DH+ + L + PD + +V AS D L ++WDL+ + ++VL
Sbjct: 156 DVYTGKLLLNLVDHTEVVR--DLTFAPDGSLILVSASRDKTL---RVWDLKDDGNMMKVL 210
Query: 257 ENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNP 316
H + + A+S D +L S G + N + ++ +L + D+ C +P
Sbjct: 211 RGHQNWVYSCAFS-PDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHH---DVVACDFSP 266
Query: 317 --AVLSAASFDGRISVYSIMGG 336
A+L+ AS+D R+ ++ G
Sbjct: 267 DGALLATASYDTRVYIWDPHNG 288
Score = 44.3 bits (103), Expect = 6e-04
Identities = 41/163 (25%), Positives = 75/163 (46%), Gaps = 12/163 (7%)
Query: 137 LVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVW 196
L+A+G N I IWD+ + T+ D++ + IL SAS VW
Sbjct: 142 LLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLT---FAPDGSLILVSASRDKTLRVW 198
Query: 197 DLRKNEPIIKV-SDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRV 255
DL+ + ++KV H N ++ A+ PD + + + + +W++ + +R
Sbjct: 199 DLKDDGNMMKVLRGHQNWVY--SCAFSPDSSMLCSVGAS----KAVFLWNMD-KYTMIRK 251
Query: 256 LENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYE 298
LE H ++A +S D LL + D ++ +P+ G++L E
Sbjct: 252 LEGHHHDVVACDFS-PDGALLATASYDTRVYIWDPHNGDILME 293
>gi|217416452 dynein, axonemal, intermediate polypeptide 2 [Homo
sapiens]
Length = 605
Score = 56.6 bits (135), Expect = 1e-07
Identities = 57/250 (22%), Positives = 90/250 (36%), Gaps = 67/250 (26%)
Query: 145 SEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDLRKNEPI 204
S+ YIWDL N P P +P + + +N + H+L +G+ WD RK +
Sbjct: 196 SDSYIWDLEN---PNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQIACWDTRKGSLV 252
Query: 205 IKVS--DHSNRMHCSGLAW-HPDVATQMVLASEDDRLPVIQMWDLRFASSPLRV------ 255
++S + S+R G W T+ AS D + + WD+R S P V
Sbjct: 253 AELSTIESSHRDPVYGTIWLQSKTGTECFSASTDGQ---VMWWDIRKMSEPTEVVILDIT 309
Query: 256 ----LENHARGILAIAWSMADPE---------LLLSCGKDAK-----ILCSNPNTGEVLY 297
LEN A G +++ + P +++SC + AK I+C+ P +Y
Sbjct: 310 KKEQLEN-ALGAISLEFESTLPTKFMVGTEQGIVISCNRKAKTSAEKIVCTFPGHHGPIY 368
Query: 298 ELPTNT---------------------------------QWCFDIQWCPRNPAVLSAASF 324
L N + D W P P V
Sbjct: 369 ALQRNPFYPKNFLTVGDWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRPTVFFTTRM 428
Query: 325 DGRISVYSIM 334
DG + ++ M
Sbjct: 429 DGTLDIWDFM 438
>gi|4506439 retinoblastoma binding protein 7 [Homo sapiens]
Length = 425
Score = 55.1 bits (131), Expect = 4e-07
Identities = 51/226 (22%), Positives = 92/226 (40%), Gaps = 30/226 (13%)
Query: 77 YKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK----HTGPVRALDVNI 132
Y + ++SG L++ ++ + L+D I AG KE I H+ V + ++
Sbjct: 180 YGLSWNSNLSGHLLSASDDHTVCLWD---INAGPKEGKIVDAKAIFTGHSAVVEDVAWHL 236
Query: 133 FQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGR 192
+L S A++ ++ IWD + T +++C+++N + ILA+ S
Sbjct: 237 LHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKT 296
Query: 193 ATVWDLRKNEPIIKVSDHSNRMHCSGL---AWHPDVATQMVLASEDDRLPVIQMWDLRFA 249
+WDLR +K+ H+ H + W P T + + D RL V WDL
Sbjct: 297 VALWDLRN----LKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNV---WDLSKI 349
Query: 250 SSP-------------LRVLENHARGILAIAWSMADPELLLSCGKD 282
L + H I +W+ +P ++ S +D
Sbjct: 350 GEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSED 395
Score = 53.1 bits (126), Expect = 1e-06
Identities = 46/217 (21%), Positives = 86/217 (39%), Gaps = 30/217 (13%)
Query: 140 SGANESEIYIWDLNNFATPM------TPGAKTQPPEDISCIAWNRQVQHILASASPSGRA 193
S +++ + +WD+N A P T + +AW+ + + S + +
Sbjct: 194 SASDDHTVCLWDIN--AGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKL 251
Query: 194 TVWDLRKN---EPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFAS 250
+WD R N +P V H+ ++C L+++P + S D + +WDLR
Sbjct: 252 MIWDTRSNTTSKPSHLVDAHTAEVNC--LSFNPYSEFILATGSADK---TVALWDLRNLK 306
Query: 251 SPLRVLENHARGILAIAWSMADPELLLSCGKDAKILC--------------SNPNTGEVL 296
L E+H I + WS + +L S G D ++ + E+L
Sbjct: 307 LKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELL 366
Query: 297 YELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSI 333
+ +T D W P P V+ + S D + ++ +
Sbjct: 367 FIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQM 403
Score = 40.0 bits (92), Expect = 0.012
Identities = 40/218 (18%), Positives = 83/218 (38%), Gaps = 68/218 (31%)
Query: 179 QVQHILASASPSGRATVWDLRKN----------EPIIKVSDHSNRMHCSGLAWHPDVATQ 228
Q HI+A+ +PS V+D K+ P +++ H + GL+W+ +++
Sbjct: 134 QNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGY--GLSWNSNLSGH 191
Query: 229 MVLASEDDRLPVIQMWDLRFASSPLRVLE------NHARGILAIAWSMADPELLLSCGKD 282
++ AS+D + +WD+ ++++ H+ + +AW + L S D
Sbjct: 192 LLSASDDH---TVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADD 248
Query: 283 AKIL--------CSNP------NTGEV--------------------------------- 295
K++ S P +T EV
Sbjct: 249 QKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLK 308
Query: 296 LYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSI 333
L+ ++ F + W P N +L+++ D R++V+ +
Sbjct: 309 LHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDL 346
Score = 30.4 bits (67), Expect = 9.7
Identities = 22/125 (17%), Positives = 48/125 (38%), Gaps = 16/125 (12%)
Query: 88 VLIAGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEI 147
+L G + + L+D + ++ + + H + + + ++AS + +
Sbjct: 287 ILATGSADKTVALWDLRNL-----KLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRL 341
Query: 148 YIWDLNNFATPMTP-GAKTQPPE----------DISCIAWNRQVQHILASASPSGRATVW 196
+WDL+ + A+ PPE IS +WN ++ S S +W
Sbjct: 342 NVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIW 401
Query: 197 DLRKN 201
+ +N
Sbjct: 402 QMAEN 406
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 54.3 bits (129), Expect = 6e-07
Identities = 62/231 (26%), Positives = 80/231 (34%), Gaps = 55/231 (23%)
Query: 801 KIPYEKQQLPKGRPGPVAGHHQMPRVQTQQ--YYPHGENPP----PPGFIMHGNVNP--- 851
++P + QLP P+ GH P + Q PH PP PP H V+P
Sbjct: 804 QVPVLEPQLPGSVFDPI-GHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPAL 862
Query: 852 -NAAGQLPTSPGHMHTQVPPYPQ------------PQRPQNGWNDPPAL---NRVP---- 891
NA Q P+ P + +PP P P PQ PP + + P
Sbjct: 863 HNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPP 922
Query: 892 -------------KKKKMPENFMPPVPITSPIMNPLGDPQ----SQMLQQQPSAPVPLSS 934
+K + P +P V + S PL P Q LQQQP P P
Sbjct: 923 LTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQP 982
Query: 935 QSSFPQPHLPGGQPFH--------GVQQPLGQTGMPPSFSKPNIEGAPGAP 977
Q Q H P +P H +QQP G P P + P P
Sbjct: 983 QPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQP 1033
Score = 40.8 bits (94), Expect = 0.007
Identities = 30/91 (32%), Positives = 36/91 (39%), Gaps = 2/91 (2%)
Query: 788 RAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHG 847
+ Q +P P P +QQL + P P Q P Q Q P + P F H
Sbjct: 949 KVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHI 1008
Query: 848 NVNPNAAGQLPTSPGHMHTQVPPYPQPQRPQ 878
P GQ P P Q PP PQP +PQ
Sbjct: 1009 QQPPPPQGQQPPHP--PPGQQPPPPQPAKPQ 1037
Score = 37.4 bits (85), Expect = 0.079
Identities = 50/191 (26%), Positives = 69/191 (36%), Gaps = 37/191 (19%)
Query: 798 ESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAGQL 857
E+ P K++ GR HH ++Q Q P + PPPP Q
Sbjct: 718 ETEMAPKSKKKGHPGREQKKHHHHHHQQMQ-QAPAPVPQQPPPP------------PQQP 764
Query: 858 PTSPGHMHTQVPPYPQPQRPQNGWNDPPAL--NRVPKKKKMPENFM-PPVPITSP----- 909
P P Q PP P P PP++ P K P F+ VP+ P
Sbjct: 765 PPPPPPQQQQQPPPPPP---------PPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGS 815
Query: 910 IMNPLGDPQSQMLQ-QQPSAP--VPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS 966
+ +P+G +L QP P +P + S P PHL V P +P S
Sbjct: 816 VFDPIGHFTQPILHLPQPELPPHLPQPPEHSTP-PHL---NQHAVVSPPALHNALPQQPS 871
Query: 967 KPNIEGAPGAP 977
+P+ A P
Sbjct: 872 RPSNRAAALPP 882
Score = 33.5 bits (75), Expect = 1.1
Identities = 37/141 (26%), Positives = 46/141 (32%), Gaps = 39/141 (27%)
Query: 863 HMHTQVPPYPQPQRPQNGWNDPPALNRVPKKKKMPENFMPPVPITSPIMNPLGDPQSQML 922
H Q P P PQ+P PP PP P PQ Q
Sbjct: 743 HQQMQQAPAPVPQQPPPPPQQPP----------------PPPP-----------PQQQ-- 773
Query: 923 QQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFSKPNIEGAPGAPIGNTF 982
QQ P P P S PF Q P+ +P + G+ PIG+
Sbjct: 774 QQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPV---------LEPQLPGSVFDPIGHFT 824
Query: 983 QHVQSLPTKKITKK-PIPDEH 1002
Q + LP ++ P P EH
Sbjct: 825 QPILHLPQPELPPHLPQPPEH 845
Score = 33.1 bits (74), Expect = 1.5
Identities = 31/108 (28%), Positives = 43/108 (39%), Gaps = 17/108 (15%)
Query: 824 PRVQTQQYYPHGENPPPPGFIMHG--NVNPNAAGQ------LPTSPGHMHTQVPPYPQP- 874
P+ QT Q NPPP H V P+ Q +P P VPP PQP
Sbjct: 206 PQTQTPQ-----PNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPP 260
Query: 875 --QRPQNGWNDPPALNRVPKKKKMPENFMPPVPITSP-IMNPLGDPQS 919
PQ + PP + P+ K + T+P ++P+ +P S
Sbjct: 261 PAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPS 308
>gi|217330644 WD repeat domain 12 protein [Homo sapiens]
Length = 423
Score = 53.5 bits (127), Expect = 1e-06
Identities = 41/150 (27%), Positives = 74/150 (49%), Gaps = 13/150 (8%)
Query: 138 VASGANESEIYIWDLNNFATPMT-PGAKTQPPEDISCIAWNRQVQHILASASPSGRATVW 196
+ S + + I +WD+ + + T G K +CI+++ + LAS S +W
Sbjct: 271 ICSASWDHTIRVWDVESGSLKSTLTGNKV-----FNCISYSPLCKR-LASGSTDRHIRLW 324
Query: 197 DLR-KNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRV 255
D R K+ ++ +S S+ + + W P Q++ S D+ ++++WD R +PL
Sbjct: 325 DPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDN---IVKLWDTRSCKAPLYD 381
Query: 256 LENHARGILAIAWSMADPELLLSCGKDAKI 285
L H +L++ W+ D LLLS G D K+
Sbjct: 382 LAAHEDKVLSVDWT--DTGLLLSGGADNKL 409
>gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens]
Length = 1298
Score = 52.8 bits (125), Expect = 2e-06
Identities = 38/168 (22%), Positives = 72/168 (42%), Gaps = 12/168 (7%)
Query: 88 VLIAGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEI 147
++ G E+ N+ +Y +A + + HT V + + + ++ SG+++ +
Sbjct: 512 MIATGCEDTNVRVY----YVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTV 567
Query: 148 YIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDLRKNEPIIKV 207
IWD A T P + + WN ++ ++L S S VWD R+ + V
Sbjct: 568 RIWDYTQDACINILNGHTAP---VRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTV 624
Query: 208 SDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRV 255
DH ++ GL HP M S D +++W L +P+++
Sbjct: 625 YDHGADVY--GLTCHPSRPFTMASCSRDS---TVRLWSLTALVTPVQI 667
Score = 47.8 bits (112), Expect = 6e-05
Identities = 40/201 (19%), Positives = 89/201 (44%), Gaps = 18/201 (8%)
Query: 136 NLVASGANESEIYIWDLNNFATPMT-PGAKTQPPEDISCIAWNRQVQHILASASPSGRAT 194
NL+A+ + + I +WD+N T PG + I ++W + +A + A
Sbjct: 383 NLLATASFDGTIKVWDINTLTAVYTSPGNEGV----IYSLSWAPGGLNCIAGGTSRNGAF 438
Query: 195 VWDLRKNEPIIKVSDH-SNRMHCSGLAW-HPDVATQMVLASEDDRLPVIQMWDLRFASSP 252
+W+++K + I + ++H +N + C +AW H D ++ + D +I+ D +
Sbjct: 439 IWNVQKGKIIQRFNEHGTNGIFC--IAWSHKD--SKRIATCSSDGFCIIRTIDGKVLHK- 493
Query: 253 LRVLENHARGILAIAWSMADPELLLSCGKDA--KILCSNPNTGEVLYELPTNTQWCFDIQ 310
H + WS + +++ + +D ++ ++ + L +T F ++
Sbjct: 494 ----YKHPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVK 549
Query: 311 WCPRNPAVLSAASFDGRISVY 331
W P +L + S DG + ++
Sbjct: 550 WSPLREGILCSGSDDGTVRIW 570
Score = 41.2 bits (95), Expect = 0.005
Identities = 38/161 (23%), Positives = 65/161 (40%), Gaps = 7/161 (4%)
Query: 182 HILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVI 241
++LA+AS G VWD+ N + N L+W P +A R
Sbjct: 383 NLLATASFDGTIKVWDI--NTLTAVYTSPGNEGVIYSLSWAPGGLN--CIAGGTSRNGAF 438
Query: 242 QMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPT 301
+W+++ R E+ GI IAWS D + + +C D + + G+VL++
Sbjct: 439 -IWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCIIRTID-GKVLHKY-K 495
Query: 302 NTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLR 342
+ F W N +++ D + VY + S L+
Sbjct: 496 HPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLK 536
Score = 35.8 bits (81), Expect = 0.23
Identities = 19/81 (23%), Positives = 38/81 (46%)
Query: 255 VLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPR 314
++ H + I AI+W +P+L S D ++ N +V+ +L + + WC
Sbjct: 54 IMSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKLDSTKGIPASLSWCWN 113
Query: 315 NPAVLSAASFDGRISVYSIMG 335
V++ S G + +++I G
Sbjct: 114 AEDVVAFVSHRGPLFIWTISG 134
>gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens]
Length = 1322
Score = 52.8 bits (125), Expect = 2e-06
Identities = 38/168 (22%), Positives = 72/168 (42%), Gaps = 12/168 (7%)
Query: 88 VLIAGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEI 147
++ G E+ N+ +Y +A + + HT V + + + ++ SG+++ +
Sbjct: 536 MIATGCEDTNVRVY----YVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTV 591
Query: 148 YIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDLRKNEPIIKV 207
IWD A T P + + WN ++ ++L S S VWD R+ + V
Sbjct: 592 RIWDYTQDACINILNGHTAP---VRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTV 648
Query: 208 SDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRV 255
DH ++ GL HP M S D +++W L +P+++
Sbjct: 649 YDHGADVY--GLTCHPSRPFTMASCSRDS---TVRLWSLTALVTPVQI 691
Score = 47.8 bits (112), Expect = 6e-05
Identities = 40/201 (19%), Positives = 89/201 (44%), Gaps = 18/201 (8%)
Query: 136 NLVASGANESEIYIWDLNNFATPMT-PGAKTQPPEDISCIAWNRQVQHILASASPSGRAT 194
NL+A+ + + I +WD+N T PG + I ++W + +A + A
Sbjct: 407 NLLATASFDGTIKVWDINTLTAVYTSPGNEGV----IYSLSWAPGGLNCIAGGTSRNGAF 462
Query: 195 VWDLRKNEPIIKVSDH-SNRMHCSGLAW-HPDVATQMVLASEDDRLPVIQMWDLRFASSP 252
+W+++K + I + ++H +N + C +AW H D ++ + D +I+ D +
Sbjct: 463 IWNVQKGKIIQRFNEHGTNGIFC--IAWSHKD--SKRIATCSSDGFCIIRTIDGKVLHK- 517
Query: 253 LRVLENHARGILAIAWSMADPELLLSCGKDA--KILCSNPNTGEVLYELPTNTQWCFDIQ 310
H + WS + +++ + +D ++ ++ + L +T F ++
Sbjct: 518 ----YKHPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVK 573
Query: 311 WCPRNPAVLSAASFDGRISVY 331
W P +L + S DG + ++
Sbjct: 574 WSPLREGILCSGSDDGTVRIW 594
Score = 41.2 bits (95), Expect = 0.005
Identities = 38/161 (23%), Positives = 65/161 (40%), Gaps = 7/161 (4%)
Query: 182 HILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVI 241
++LA+AS G VWD+ N + N L+W P +A R
Sbjct: 407 NLLATASFDGTIKVWDI--NTLTAVYTSPGNEGVIYSLSWAPGGLN--CIAGGTSRNGAF 462
Query: 242 QMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPT 301
+W+++ R E+ GI IAWS D + + +C D + + G+VL++
Sbjct: 463 -IWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCIIRTID-GKVLHKY-K 519
Query: 302 NTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLR 342
+ F W N +++ D + VY + S L+
Sbjct: 520 HPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLK 560
Score = 35.8 bits (81), Expect = 0.23
Identities = 19/81 (23%), Positives = 38/81 (46%)
Query: 255 VLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPR 314
++ H + I AI+W +P+L S D ++ N +V+ +L + + WC
Sbjct: 78 IMSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKLDSTKGIPASLSWCWN 137
Query: 315 NPAVLSAASFDGRISVYSIMG 335
V++ S G + +++I G
Sbjct: 138 AEDVVAFVSHRGPLFIWTISG 158
>gi|13129110 WD repeat domain 77 [Homo sapiens]
Length = 342
Score = 52.8 bits (125), Expect = 2e-06
Identities = 46/241 (19%), Positives = 101/241 (41%), Gaps = 13/241 (5%)
Query: 93 GENGNIILYDPSKI----IAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVA-SGANESEI 147
GE G ++ D + + ++ +++++ K+ V++ + A SG+ + I
Sbjct: 90 GERGILVASDSGAVELWELDENETLIVSKFCKYEHDDIVSTVSVLSSGTQAVSGSKDICI 149
Query: 148 YIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDLRKNEPIIKV 207
+WDL A + + ++C+A + + S S R +WD R +P ++
Sbjct: 150 KVWDL---AQQVVLSSYRAHAAQVTCVAASPHKDSVFLSCSEDNRILLWDTRCPKPASQI 206
Query: 208 SDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILAIA 267
+ + LAWHP + V E+ + ++ D + S L H++ + +
Sbjct: 207 GCSAPGYLPTSLAWHPQQSEVFVFGDENGTVSLV---DTKSTSCVLSSAV-HSQCVTGLV 262
Query: 268 WSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGR 327
+S L S +D + + + E L+ + + D W P N ++L+ +D +
Sbjct: 263 FSPHSVPFLASLSEDCSLAVLDSSLSE-LFRSQAHRDFVRDATWSPLNHSLLTTVGWDHQ 321
Query: 328 I 328
+
Sbjct: 322 V 322
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 52.8 bits (125), Expect = 2e-06
Identities = 66/237 (27%), Positives = 81/237 (34%), Gaps = 33/237 (13%)
Query: 788 RAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHG 847
+ QG P G P+ P P+G P P G+ P+ P G PPP G
Sbjct: 96 KPQGPPPQGGNQPQGPPPPPGKPQGPP-PQGGNR--PQGPPPPGKPQG--PPPQGDKSRS 150
Query: 848 NVNPNAAGQLPTSPGHMHTQVPPYPQPQRPQNGWNDPPALNRVPKKKKMPENFMPPVP-- 905
+P Q P G Q PP P P +PQ PP + P+ P P P
Sbjct: 151 PRSPPGKPQGPPPQGGNQPQGPP-PPPGKPQG---PPPQGGKKPQGPPPPGKPQGPPPQG 206
Query: 906 -----ITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQ----------PHLPGGQPFH 950
SP P G P Q Q P P Q PQ P P G P
Sbjct: 207 DKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQ 266
Query: 951 G------VQQPLGQTGMPPSFSKPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDE 1001
G + P G+ PP N +G P P G Q Q+ P + P P +
Sbjct: 267 GGSKSQSARSPPGKPQGPPQQEGNNPQGPP-PPAGGNPQQPQAPPAGQPQGPPRPPQ 322
Score = 50.1 bits (118), Expect = 1e-05
Identities = 57/193 (29%), Positives = 72/193 (37%), Gaps = 23/193 (11%)
Query: 788 RAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHG 847
+ QG P G P+ P P+G P P G + P+ P G PPP G
Sbjct: 157 KPQGPPPQGGNQPQGPPPPPGKPQGPP-PQGG--KKPQGPPPPGKPQG--PPPQGDKSRS 211
Query: 848 NVNPNAAGQLPTSPGHMHTQVPPYPQPQRPQNGWNDPPALNRVPKKKKMPENFMPPVPIT 907
+ +P Q P G Q PP P P +PQ PP P+ P+ PP
Sbjct: 212 SQSPPGKPQGPPPQGGNQPQGPP-PPPGKPQG----PP-----PQGGNKPQGPPPPGKPQ 261
Query: 908 SPIMNPLGDPQSQMLQQQPSAPV-PLSSQSSFPQ--PHLPGGQPFHGVQQPLGQTGMPPS 964
P G +SQ + P P P + + PQ P GG P P GQ PP
Sbjct: 262 GPPAQ--GGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPP- 318
Query: 965 FSKPNIEGAPGAP 977
+P G P P
Sbjct: 319 --RPPQGGRPSRP 329
Score = 47.4 bits (111), Expect = 8e-05
Identities = 59/197 (29%), Positives = 71/197 (36%), Gaps = 19/197 (9%)
Query: 790 QGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNV 849
QG G P+ P P+G P P G+ P+ P G PPP G
Sbjct: 37 QGPSPQGGNKPQGPPPPPGKPQGPP-PQGGNK--PQGPPPPGKPQG--PPPQGDKSRSPR 91
Query: 850 NPNAAGQLPTSPGHMHTQVPPYPQPQRPQNGWNDPPALNRVPKKKKMPENFMPPVP---- 905
+P Q P G Q PP P P +PQ PP P+ P P P
Sbjct: 92 SPPGKPQGPPPQGGNQPQGPP-PPPGKPQ---GPPPQGGNRPQGPPPPGKPQGPPPQGDK 147
Query: 906 ITSPIMNPLGDPQSQMLQ--QQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPP 963
SP +P G PQ Q QP P P + P P GG+ G P G PP
Sbjct: 148 SRSP-RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ--GGKKPQGPPPPGKPQGPPP 204
Query: 964 SFSKP-NIEGAPGAPIG 979
K + + PG P G
Sbjct: 205 QGDKSRSSQSPPGKPQG 221
>gi|157739942 gemin 5 [Homo sapiens]
Length = 1508
Score = 52.0 bits (123), Expect = 3e-06
Identities = 32/96 (33%), Positives = 48/96 (50%), Gaps = 11/96 (11%)
Query: 137 LVASGANESEIYIWDLNNF--ATPMTPGAKTQPPEDIS-------CIAWNRQVQHILASA 187
L+ASG+N + IY+ +L ++P +P T+P +S +AW+ L SA
Sbjct: 599 LMASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSA 658
Query: 188 SPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHP 223
S G A VWD + EP+ H R+ C +AW P
Sbjct: 659 SYDGTAQVWDALREEPLCNFRGHRGRLLC--VAWSP 692
Score = 45.8 bits (107), Expect = 2e-04
Identities = 59/249 (23%), Positives = 102/249 (40%), Gaps = 41/249 (16%)
Query: 66 SHRYHK-----LIWGP----YKMDSKGD-VSGVLIAGGENGNIILYDPSKIIAG----DK 111
S YHK L WGP + +GD S L + G G ++ ++P K+ +K
Sbjct: 465 SSTYHKKTVYTLAWGPPVPPMSLGGEGDRPSLALYSCGGEGIVLQHNPWKLSGEAFDINK 524
Query: 112 EVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDI 171
+ + K+ PV ++A G + I I+ + N T Q + +
Sbjct: 525 LIRDTNSIKYKLPVHTEISWKADGKIMALGNEDGSIEIFQIPNLKLICTI---QQHHKLV 581
Query: 172 SCIAWNRQ------VQHILASASPSGRATVWDLRK------------NEPIIKVSDHSNR 213
+ I+W+ + + +++AS S + V +L+ EP +S H+ +
Sbjct: 582 NTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAK 641
Query: 214 MHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILAIAWSMADP 273
+ + +AW P ++V AS D Q+WD PL H +L +AWS DP
Sbjct: 642 I--TSVAWSPHHDGRLVSASYDG---TAQVWDA-LREEPLCNFRGHRGRLLCVAWSPLDP 695
Query: 274 ELLLSCGKD 282
+ + S D
Sbjct: 696 DCIYSGADD 704
Score = 37.0 bits (84), Expect = 0.10
Identities = 36/134 (26%), Positives = 58/134 (43%), Gaps = 10/134 (7%)
Query: 182 HILASASPSGRATVWDLRKNEPIIKVSDHSNRMHC-SGLAWHPDVATQMVLASEDDRLPV 240
++ A++S G +WD+ E V++H+ H S L W P V +V S D++ V
Sbjct: 80 NLCATSSDDGTVKIWDV---ETKTVVTEHALHQHTISTLHWSPRVKDLIV--SGDEKGVV 134
Query: 241 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSN-PNTGEVLYEL 299
W R S L + R I + S +L+ KD ++ + GEV++ L
Sbjct: 135 FCYWFNRNDSQHLFI---EPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDISKKGEVIHRL 191
Query: 300 PTNTQWCFDIQWCP 313
+ I WCP
Sbjct: 192 RGHDDEIHSIAWCP 205
Score = 33.9 bits (76), Expect = 0.88
Identities = 46/217 (21%), Positives = 81/217 (37%), Gaps = 67/217 (30%)
Query: 138 VASGANESEIYIWDL----NNFATP-MTPGAKTQPPEDISCIAWNRQVQHILASASPSGR 192
+A G + I +W+ NN+ G K++ ++ + W+ + LA + G+
Sbjct: 395 LAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSK----VTALCWHPTKEGCLAFGTDDGK 450
Query: 193 ATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSP 252
++D N+P ++S ++ LAW P V M L E DR
Sbjct: 451 VGLYDTYSNKP-PQISSTYHKKTVYTLAWGPPV-PPMSLGGEGDR--------------- 493
Query: 253 LRVLENHARGILAIAWSMADPEL-LLSCGKDAKILCSNP---------------NTGEVL 296
P L L SCG + +L NP +T +
Sbjct: 494 --------------------PSLALYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIK 533
Query: 297 YELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSI 333
Y+LP +T +I W + +++ + DG I ++ I
Sbjct: 534 YKLPVHT----EISW-KADGKIMALGNEDGSIEIFQI 565
Score = 31.2 bits (69), Expect = 5.7
Identities = 34/156 (21%), Positives = 66/156 (42%), Gaps = 30/156 (19%)
Query: 219 LAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILAIAWSM---ADPEL 275
++W D M L +ED + + Q+ +L+ + ++ H + + I+W + PEL
Sbjct: 542 ISWKAD-GKIMALGNEDGSIEIFQIPNLKLICT----IQQHHKLVNTISWHHEHGSQPEL 596
Query: 276 --LLSCGKDAKILC---------SNPNTGEVLYE----LPTNTQWCFDIQWCPRNPAVLS 320
L++ G + ++ S+P + + E L +T + W P + L
Sbjct: 597 SYLMASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLV 656
Query: 321 AASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNL 356
+AS+DG V+ D LR++ + G L
Sbjct: 657 SASYDGTAQVW-------DALREEPLCNFRGHRGRL 685
>gi|118402582 cell division cycle 20 [Homo sapiens]
Length = 499
Score = 51.6 bits (122), Expect = 4e-06
Identities = 59/232 (25%), Positives = 102/232 (43%), Gaps = 30/232 (12%)
Query: 124 PVRALDV----NIFQTNLV--ASG-----ANESEIYIWDLNNFATPMTPGAKTQPPEDIS 172
P R LD N + NLV +SG A ++ +Y+W ++ + QP E IS
Sbjct: 172 PDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSASS-GDILQLLQMEQPGEYIS 230
Query: 173 CIAWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLA 232
+AW ++ + LA + S +WD+++ + + ++ HS R+ L+W+ +
Sbjct: 231 SVAWIKEGNY-LAVGTSSAEVQLWDVQQQKRLRNMTSHSARV--GSLSWN------SYIL 281
Query: 233 SEDDRLPVIQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKD--AKILCSNP 290
S R I D+R A + L H++ + + W+ D L S G D + S P
Sbjct: 282 SSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWA-PDGRHLASGGNDNLVNVWPSAP 340
Query: 291 NTGEVLYELPTNTQW---CFDIQWCPRNPAVLS--AASFDGRISVYSIMGGS 337
G + L T TQ + WCP VL+ + D I ++++ G+
Sbjct: 341 GEGGWV-PLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGA 391
Score = 36.2 bits (82), Expect = 0.18
Identities = 37/160 (23%), Positives = 75/160 (46%), Gaps = 11/160 (6%)
Query: 90 IAGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESE--I 147
+A G N N++ PS G V + +H G V+A+ +Q+N++A+G S+ I
Sbjct: 324 LASGGNDNLVNVWPSAPGEGGW-VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHI 382
Query: 148 YIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILAS-ASPSGRATVWDLRKNEPIIK 206
IW++ + A A +Q + I W+ + +++ + +W + +
Sbjct: 383 RIWNVCSGACLSAVDAHSQ----VCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAE 438
Query: 207 VSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDL 246
+ H++R+ L PD AT + A+ D+ L + + ++L
Sbjct: 439 LKGHTSRV--LSLTMSPDGAT-VASAAADETLRLWRCFEL 475
>gi|4758178 dynein, cytoplasmic 1, intermediate chain 1 isoform a
[Homo sapiens]
Length = 645
Score = 51.2 bits (121), Expect = 5e-06
Identities = 61/313 (19%), Positives = 117/313 (37%), Gaps = 37/313 (11%)
Query: 49 DLSDPSLDMKSCATFSSSHRYHKLIWGPYK----MDSKGDVSGVLIAGGENGNIILYDPS 104
+L + D+++ A S + +++ W ++ MD +++A N ++P
Sbjct: 259 ELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPD 318
Query: 105 KIIAGDKEVVIAQNDKHTGP---------VRALDVNIFQTNLVASGANESEIYIWDLNNF 155
+ +V K T P V ++ F NLV G +I +WD +
Sbjct: 319 GVA-----LVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSH 373
Query: 156 A------TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDL----RKNEPII 205
TP++ A T P ++ + Q H L + S G+ W L E +
Sbjct: 374 RRTPVQRTPLSAAAHTHPVYCVNVVG--TQNAHNLITVSTDGKMCSWSLDMLSTPQESME 431
Query: 206 KVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILA 265
V + S + +G+A+ V+ SE+ + + V E H +
Sbjct: 432 LVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIG--EVFEGHQGPVTG 489
Query: 266 IAWSMAD-----PELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLS 320
I MA L ++ D + + LY N + +D+ W P +PA+ +
Sbjct: 490 INCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFA 549
Query: 321 AASFDGRISVYSI 333
GR+ ++++
Sbjct: 550 CVDGMGRLDLWNL 562
>gi|207113124 dynein, cytoplasmic 1, intermediate chain 1 isoform c
[Homo sapiens]
Length = 608
Score = 51.2 bits (121), Expect = 5e-06
Identities = 61/313 (19%), Positives = 117/313 (37%), Gaps = 37/313 (11%)
Query: 49 DLSDPSLDMKSCATFSSSHRYHKLIWGPYK----MDSKGDVSGVLIAGGENGNIILYDPS 104
+L + D+++ A S + +++ W ++ MD +++A N ++P
Sbjct: 222 ELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPD 281
Query: 105 KIIAGDKEVVIAQNDKHTGP---------VRALDVNIFQTNLVASGANESEIYIWDLNNF 155
+ +V K T P V ++ F NLV G +I +WD +
Sbjct: 282 GVA-----LVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSH 336
Query: 156 A------TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDL----RKNEPII 205
TP++ A T P ++ + Q H L + S G+ W L E +
Sbjct: 337 RRTPVQRTPLSAAAHTHPVYCVNVVG--TQNAHNLITVSTDGKMCSWSLDMLSTPQESME 394
Query: 206 KVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILA 265
V + S + +G+A+ V+ SE+ + + V E H +
Sbjct: 395 LVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIG--EVFEGHQGPVTG 452
Query: 266 IAWSMAD-----PELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLS 320
I MA L ++ D + + LY N + +D+ W P +PA+ +
Sbjct: 453 INCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFA 512
Query: 321 AASFDGRISVYSI 333
GR+ ++++
Sbjct: 513 CVDGMGRLDLWNL 525
>gi|207113122 dynein, cytoplasmic 1, intermediate chain 1 isoform b
[Homo sapiens]
Length = 628
Score = 51.2 bits (121), Expect = 5e-06
Identities = 61/313 (19%), Positives = 117/313 (37%), Gaps = 37/313 (11%)
Query: 49 DLSDPSLDMKSCATFSSSHRYHKLIWGPYK----MDSKGDVSGVLIAGGENGNIILYDPS 104
+L + D+++ A S + +++ W ++ MD +++A N ++P
Sbjct: 242 ELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPD 301
Query: 105 KIIAGDKEVVIAQNDKHTGP---------VRALDVNIFQTNLVASGANESEIYIWDLNNF 155
+ +V K T P V ++ F NLV G +I +WD +
Sbjct: 302 GVA-----LVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSH 356
Query: 156 A------TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDL----RKNEPII 205
TP++ A T P ++ + Q H L + S G+ W L E +
Sbjct: 357 RRTPVQRTPLSAAAHTHPVYCVNVVG--TQNAHNLITVSTDGKMCSWSLDMLSTPQESME 414
Query: 206 KVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILA 265
V + S + +G+A+ V+ SE+ + + V E H +
Sbjct: 415 LVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIG--EVFEGHQGPVTG 472
Query: 266 IAWSMAD-----PELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLS 320
I MA L ++ D + + LY N + +D+ W P +PA+ +
Sbjct: 473 INCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFA 532
Query: 321 AASFDGRISVYSI 333
GR+ ++++
Sbjct: 533 CVDGMGRLDLWNL 545
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 51.2 bits (121), Expect = 5e-06
Identities = 48/174 (27%), Positives = 72/174 (41%), Gaps = 31/174 (17%)
Query: 802 IPYEKQQLPKGRPGPVAGHHQM---PRVQTQQYYPHGENPP----PPGFIMHGNVNPNAA 854
+ Y +Q P G+ GP +G+ Q P Q +P + PP PP H P+
Sbjct: 445 LSYTQQIPPYGQQGP-SGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQ--PSYQ 501
Query: 855 GQLPTSPGHMHTQVPPYPQ-PQRPQNGWNDPPALNRVPKKKKMPENFMPPVPITSPIMNP 913
Q + P + + PPY Q P +P + + P ++ ++ P++ P
Sbjct: 502 QQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQS-----------QPP 550
Query: 914 LGDPQSQM--LQQQPSAPVP--LSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPP 963
PQ+Q QQQP P P LS Q+++PQP Q Q Q PP
Sbjct: 551 YSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQ-----QTAYSQQRFPP 599
Score = 34.7 bits (78), Expect = 0.51
Identities = 46/170 (27%), Positives = 55/170 (32%), Gaps = 30/170 (17%)
Query: 806 KQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAGQLPTSPGHMH 865
K+ PK +P AG M QT Q G++ P PT H
Sbjct: 1124 KKSQPKIQPPSPAGSGSMQGPQTPQ-------STSSSMAEGGDLKP------PTPASTPH 1170
Query: 866 TQVPPYPQPQRPQNGWNDPPALNRVPKKKKMPENFMPPVPITSPIMN-----------PL 914
+Q+PP P R N A N N M P P P MN P
Sbjct: 1171 SQIPPLPGMSR-SNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPN 1229
Query: 915 GDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQP-LGQTGMPP 963
DP M + S P S Q P+ G P+ P LG M P
Sbjct: 1230 KDPYGSMRKAPGSDPFMSSGQG----PNGGMGDPYSRAAGPGLGNVAMGP 1275
Score = 33.5 bits (75), Expect = 1.1
Identities = 38/149 (25%), Positives = 51/149 (34%), Gaps = 29/149 (19%)
Query: 797 HESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYY----PHGENPPPPGFIMHGNVNPN 852
H + P QQ P P + Q P+ Q Q P+ + P P P+
Sbjct: 477 HPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQP---------PH 527
Query: 853 AAGQLPTSPGHMHTQVPPYPQPQRPQNGWNDPPALNRVPKKKKMPENFMPPVPITSPIMN 912
P TQ P QP ++ P A + P +++ P+ P P T
Sbjct: 528 QQSPAPYPSQQSTTQQHPQSQPP-----YSQPQA--QSPYQQQQPQQ---PAPSTLSQQA 577
Query: 913 PLGDPQSQMLQQQPSAPVPLSSQSSFPQP 941
PQSQ QQ SQ FP P
Sbjct: 578 AYPQPQSQQSQQ------TAYSQQRFPPP 600
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 51.2 bits (121), Expect = 5e-06
Identities = 48/174 (27%), Positives = 72/174 (41%), Gaps = 31/174 (17%)
Query: 802 IPYEKQQLPKGRPGPVAGHHQM---PRVQTQQYYPHGENPP----PPGFIMHGNVNPNAA 854
+ Y +Q P G+ GP +G+ Q P Q +P + PP PP H P+
Sbjct: 445 LSYTQQIPPYGQQGP-SGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQ--PSYQ 501
Query: 855 GQLPTSPGHMHTQVPPYPQ-PQRPQNGWNDPPALNRVPKKKKMPENFMPPVPITSPIMNP 913
Q + P + + PPY Q P +P + + P ++ ++ P++ P
Sbjct: 502 QQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQS-----------QPP 550
Query: 914 LGDPQSQM--LQQQPSAPVP--LSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPP 963
PQ+Q QQQP P P LS Q+++PQP Q Q Q PP
Sbjct: 551 YSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQ-----QTAYSQQRFPP 599
Score = 34.7 bits (78), Expect = 0.51
Identities = 46/170 (27%), Positives = 55/170 (32%), Gaps = 30/170 (17%)
Query: 806 KQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAGQLPTSPGHMH 865
K+ PK +P AG M QT Q G++ P PT H
Sbjct: 1124 KKSQPKIQPPSPAGSGSMQGPQTPQ-------STSSSMAEGGDLKP------PTPASTPH 1170
Query: 866 TQVPPYPQPQRPQNGWNDPPALNRVPKKKKMPENFMPPVPITSPIMN-----------PL 914
+Q+PP P R N A N N M P P P MN P
Sbjct: 1171 SQIPPLPGMSR-SNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPN 1229
Query: 915 GDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQP-LGQTGMPP 963
DP M + S P S Q P+ G P+ P LG M P
Sbjct: 1230 KDPYGSMRKAPGSDPFMSSGQG----PNGGMGDPYSRAAGPGLGNVAMGP 1275
Score = 33.5 bits (75), Expect = 1.1
Identities = 38/149 (25%), Positives = 51/149 (34%), Gaps = 29/149 (19%)
Query: 797 HESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYY----PHGENPPPPGFIMHGNVNPN 852
H + P QQ P P + Q P+ Q Q P+ + P P P+
Sbjct: 477 HPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQP---------PH 527
Query: 853 AAGQLPTSPGHMHTQVPPYPQPQRPQNGWNDPPALNRVPKKKKMPENFMPPVPITSPIMN 912
P TQ P QP ++ P A + P +++ P+ P P T
Sbjct: 528 QQSPAPYPSQQSTTQQHPQSQPP-----YSQPQA--QSPYQQQQPQQ---PAPSTLSQQA 577
Query: 913 PLGDPQSQMLQQQPSAPVPLSSQSSFPQP 941
PQSQ QQ SQ FP P
Sbjct: 578 AYPQPQSQQSQQ------TAYSQQRFPPP 600
>gi|8923881 WD SOCS-box protein 2 [Homo sapiens]
Length = 404
Score = 51.2 bits (121), Expect = 5e-06
Identities = 43/164 (26%), Positives = 76/164 (46%), Gaps = 12/164 (7%)
Query: 137 LVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVW 196
++A+G N+ +I IW++ + D+S + IL SAS +W
Sbjct: 125 VLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLS---FTPSGSLILVSASRDKTLRIW 181
Query: 197 DLRKNEPIIKV-SDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRV 255
DL K+ I+V S H ++C ++ PD + A E + +W +R + + +R
Sbjct: 182 DLNKHGKQIQVLSGHLQWVYCCSIS--PDCSMLCSAAGEKS----VFLWSMR-SYTLIRK 234
Query: 256 LENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYEL 299
LE H +++ +S D LL++ D ++ +P TGE L L
Sbjct: 235 LEGHQSSVVSCDFS-PDSALLVTASYDTNVIMWDPYTGERLRSL 277
>gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 50.8 bits (120), Expect = 7e-06
Identities = 58/223 (26%), Positives = 94/223 (42%), Gaps = 29/223 (13%)
Query: 125 VRALDVNIFQTNLVASGANESEIYIW-DLNNFATPMTPGAKTQPPEDISCIAWNRQVQHI 183
V +LD N T L+A+G+ + IW + N A+ T G P I + WNR+ +I
Sbjct: 240 VTSLDWNTNGT-LLATGSYDGFARIWTEDGNLAS--TLGQHKGP---IFALKWNRKGNYI 293
Query: 184 LASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQM 243
L SA +WD E + HS + W + T S D + V ++
Sbjct: 294 L-SAGVDKTTIIWDAHTGEAKQQFPFHS--APALDVDWQNN--TTFASCSTDMCIHVCRL 348
Query: 244 WDLRFASSPLRVLENHARGILAIAWSMADPE--LLLSCGKDAKILCSNPNTGEVLYELPT 301
P++ + H + AI W DP LL SC D + + +++L
Sbjct: 349 G----CDRPVKTFQGHTNEVNAIKW---DPSGMLLASCSDDMTLKIWSMKQEVCIHDLQA 401
Query: 302 NTQWCFDIQWCPRNPA--------VLSAASFDGRISVYSIMGG 336
+ + + I+W P PA +L++ASFD + ++ I G
Sbjct: 402 HNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERG 444
Score = 41.6 bits (96), Expect = 0.004
Identities = 51/213 (23%), Positives = 82/213 (38%), Gaps = 37/213 (17%)
Query: 143 NESEIYIWDLNNFATPMTPGAKTQPPE-----------DISCIAWNRQVQHILASASPSG 191
N E +NN A PM + + P ++ AWN V +LAS S
Sbjct: 145 NGEENRAHSVNNHAKPMEIDGEVEIPSSKATVLRGHESEVFICAWN-PVSDLLASGSGDS 203
Query: 192 RATVWDLRKNEP----------IIKVSDHS--NRMHCSGLAWHPDVATQMVLASEDDRLP 239
A +W+L +N I+ H + + L W+ + T + S D
Sbjct: 204 TARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTN-GTLLATGSYDG--- 259
Query: 240 VIQMW--DLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLY 297
++W D AS+ L H I A+ W+ +LS G D + + +TGE
Sbjct: 260 FARIWTEDGNLAST----LGQHKGPIFALKWNRKG-NYILSAGVDKTTIIWDAHTGEAKQ 314
Query: 298 ELPTNTQWCFDIQWCPRNPAVLSAASFDGRISV 330
+ P ++ D+ W +N ++ S D I V
Sbjct: 315 QFPFHSAPALDVDW--QNNTTFASCSTDMCIHV 345
>gi|213021188 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 50.8 bits (120), Expect = 7e-06
Identities = 58/223 (26%), Positives = 94/223 (42%), Gaps = 29/223 (13%)
Query: 125 VRALDVNIFQTNLVASGANESEIYIW-DLNNFATPMTPGAKTQPPEDISCIAWNRQVQHI 183
V +LD N T L+A+G+ + IW + N A+ T G P I + WNR+ +I
Sbjct: 240 VTSLDWNTNGT-LLATGSYDGFARIWTEDGNLAS--TLGQHKGP---IFALKWNRKGNYI 293
Query: 184 LASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQM 243
L SA +WD E + HS + W + T S D + V ++
Sbjct: 294 L-SAGVDKTTIIWDAHTGEAKQQFPFHS--APALDVDWQNN--TTFASCSTDMCIHVCRL 348
Query: 244 WDLRFASSPLRVLENHARGILAIAWSMADPE--LLLSCGKDAKILCSNPNTGEVLYELPT 301
P++ + H + AI W DP LL SC D + + +++L
Sbjct: 349 G----CDRPVKTFQGHTNEVNAIKW---DPSGMLLASCSDDMTLKIWSMKQEVCIHDLQA 401
Query: 302 NTQWCFDIQWCPRNPA--------VLSAASFDGRISVYSIMGG 336
+ + + I+W P PA +L++ASFD + ++ I G
Sbjct: 402 HNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERG 444
Score = 41.6 bits (96), Expect = 0.004
Identities = 51/213 (23%), Positives = 82/213 (38%), Gaps = 37/213 (17%)
Query: 143 NESEIYIWDLNNFATPMTPGAKTQPPE-----------DISCIAWNRQVQHILASASPSG 191
N E +NN A PM + + P ++ AWN V +LAS S
Sbjct: 145 NGEENRAHSVNNHAKPMEIDGEVEIPSSKATVLRGHESEVFICAWN-PVSDLLASGSGDS 203
Query: 192 RATVWDLRKNEP----------IIKVSDHS--NRMHCSGLAWHPDVATQMVLASEDDRLP 239
A +W+L +N I+ H + + L W+ + T + S D
Sbjct: 204 TARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTN-GTLLATGSYDG--- 259
Query: 240 VIQMW--DLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLY 297
++W D AS+ L H I A+ W+ +LS G D + + +TGE
Sbjct: 260 FARIWTEDGNLAST----LGQHKGPIFALKWNRKG-NYILSAGVDKTTIIWDAHTGEAKQ 314
Query: 298 ELPTNTQWCFDIQWCPRNPAVLSAASFDGRISV 330
+ P ++ D+ W +N ++ S D I V
Sbjct: 315 QFPFHSAPALDVDW--QNNTTFASCSTDMCIHV 345
>gi|213021186 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 50.8 bits (120), Expect = 7e-06
Identities = 58/223 (26%), Positives = 94/223 (42%), Gaps = 29/223 (13%)
Query: 125 VRALDVNIFQTNLVASGANESEIYIW-DLNNFATPMTPGAKTQPPEDISCIAWNRQVQHI 183
V +LD N T L+A+G+ + IW + N A+ T G P I + WNR+ +I
Sbjct: 291 VTSLDWNTNGT-LLATGSYDGFARIWTEDGNLAS--TLGQHKGP---IFALKWNRKGNYI 344
Query: 184 LASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQM 243
L SA +WD E + HS + W + T S D + V ++
Sbjct: 345 L-SAGVDKTTIIWDAHTGEAKQQFPFHS--APALDVDWQNN--TTFASCSTDMCIHVCRL 399
Query: 244 WDLRFASSPLRVLENHARGILAIAWSMADPE--LLLSCGKDAKILCSNPNTGEVLYELPT 301
P++ + H + AI W DP LL SC D + + +++L
Sbjct: 400 G----CDRPVKTFQGHTNEVNAIKW---DPSGMLLASCSDDMTLKIWSMKQEVCIHDLQA 452
Query: 302 NTQWCFDIQWCPRNPA--------VLSAASFDGRISVYSIMGG 336
+ + + I+W P PA +L++ASFD + ++ I G
Sbjct: 453 HNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERG 495
Score = 41.6 bits (96), Expect = 0.004
Identities = 51/213 (23%), Positives = 82/213 (38%), Gaps = 37/213 (17%)
Query: 143 NESEIYIWDLNNFATPMTPGAKTQPPE-----------DISCIAWNRQVQHILASASPSG 191
N E +NN A PM + + P ++ AWN V +LAS S
Sbjct: 196 NGEENRAHSVNNHAKPMEIDGEVEIPSSKATVLRGHESEVFICAWN-PVSDLLASGSGDS 254
Query: 192 RATVWDLRKNEP----------IIKVSDHS--NRMHCSGLAWHPDVATQMVLASEDDRLP 239
A +W+L +N I+ H + + L W+ + T + S D
Sbjct: 255 TARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTN-GTLLATGSYDG--- 310
Query: 240 VIQMW--DLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLY 297
++W D AS+ L H I A+ W+ +LS G D + + +TGE
Sbjct: 311 FARIWTEDGNLAST----LGQHKGPIFALKWNRKG-NYILSAGVDKTTIIWDAHTGEAKQ 365
Query: 298 ELPTNTQWCFDIQWCPRNPAVLSAASFDGRISV 330
+ P ++ D+ W +N ++ S D I V
Sbjct: 366 QFPFHSAPALDVDW--QNNTTFASCSTDMCIHV 396
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,214,158
Number of Sequences: 37866
Number of extensions: 2606836
Number of successful extensions: 14120
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 68
Number of HSP's successfully gapped in prelim test: 695
Number of HSP's that attempted gapping in prelim test: 10085
Number of HSP's gapped (non-prelim): 3537
length of query: 1106
length of database: 18,247,518
effective HSP length: 113
effective length of query: 993
effective length of database: 13,968,660
effective search space: 13870879380
effective search space used: 13870879380
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.