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Search of human proteins with 23957698
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23957698 luman-recruiting factor [Homo sapiens]
(639 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23957698 luman-recruiting factor [Homo sapiens] 1293 0.0
gi|34482047 adaptor-related protein complex 3, beta 2 subunit [H... 57 5e-08
gi|55956788 nucleolin [Homo sapiens] 55 2e-07
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 55 2e-07
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 54 6e-07
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 53 8e-07
gi|17975763 myelin transcription factor 1 [Homo sapiens] 53 1e-06
gi|210032580 SET domain containing 1B [Homo sapiens] 53 1e-06
gi|33946282 hypothetical protein LOC25962 isoform 1 [Homo sapiens] 52 1e-06
gi|33946280 hypothetical protein LOC25962 isoform 2 [Homo sapiens] 52 1e-06
gi|4503257 death-domain associated protein isoform a [Homo sapiens] 52 2e-06
gi|215422388 death-domain associated protein isoform a [Homo sap... 52 2e-06
gi|215422366 death-domain associated protein isoform b [Homo sap... 52 2e-06
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 52 2e-06
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 51 3e-06
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami... 51 4e-06
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 51 4e-06
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 51 4e-06
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 51 4e-06
gi|156071452 nardilysin isoform b [Homo sapiens] 50 5e-06
gi|156071450 nardilysin isoform a [Homo sapiens] 50 5e-06
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 50 6e-06
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 50 6e-06
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 49 1e-05
gi|115529449 upstream binding transcription factor, RNA polymera... 49 2e-05
gi|115529451 upstream binding transcription factor, RNA polymera... 49 2e-05
gi|7657671 upstream binding transcription factor, RNA polymerase... 49 2e-05
gi|4505999 protein phosphatase 1G [Homo sapiens] 48 2e-05
gi|29826282 protein phosphatase 1G [Homo sapiens] 48 2e-05
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi... 48 3e-05
>gi|23957698 luman-recruiting factor [Homo sapiens]
Length = 639
Score = 1293 bits (3345), Expect = 0.0
Identities = 639/639 (100%), Positives = 639/639 (100%)
Query: 1 MPQPSVSGMDPPFGDAFRSHTFSEQTLMSTDLLANSSDPDFMYELDREMNYQQNPRDNFL 60
MPQPSVSGMDPPFGDAFRSHTFSEQTLMSTDLLANSSDPDFMYELDREMNYQQNPRDNFL
Sbjct: 1 MPQPSVSGMDPPFGDAFRSHTFSEQTLMSTDLLANSSDPDFMYELDREMNYQQNPRDNFL 60
Query: 61 SLEDCKDIENLESFTDVLDNEGALTSNWEQWDTYCEDLTKYTKLTSCDIWGTKEVDYLGL 120
SLEDCKDIENLESFTDVLDNEGALTSNWEQWDTYCEDLTKYTKLTSCDIWGTKEVDYLGL
Sbjct: 61 SLEDCKDIENLESFTDVLDNEGALTSNWEQWDTYCEDLTKYTKLTSCDIWGTKEVDYLGL 120
Query: 121 DDFSSPYQDEEVISKTPTLAQLNSEDSQSVSDSLYYPDSLFSVKQNPLPSSFPGKKITSR 180
DDFSSPYQDEEVISKTPTLAQLNSEDSQSVSDSLYYPDSLFSVKQNPLPSSFPGKKITSR
Sbjct: 121 DDFSSPYQDEEVISKTPTLAQLNSEDSQSVSDSLYYPDSLFSVKQNPLPSSFPGKKITSR 180
Query: 181 AAAPVCSSKTLQAEVPLSDCVQKASKPTSSTQIMVKTNMYHNEKVNFHVECKDYVKKAKV 240
AAAPVCSSKTLQAEVPLSDCVQKASKPTSSTQIMVKTNMYHNEKVNFHVECKDYVKKAKV
Sbjct: 181 AAAPVCSSKTLQAEVPLSDCVQKASKPTSSTQIMVKTNMYHNEKVNFHVECKDYVKKAKV 240
Query: 241 KINPVQQSRPLLSQIHTDAAKENTCYCGAVAKRQEKKGMEPLQGHATPALPFKETQELLL 300
KINPVQQSRPLLSQIHTDAAKENTCYCGAVAKRQEKKGMEPLQGHATPALPFKETQELLL
Sbjct: 241 KINPVQQSRPLLSQIHTDAAKENTCYCGAVAKRQEKKGMEPLQGHATPALPFKETQELLL 300
Query: 301 SPLPQEGPGSLAAGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEED 360
SPLPQEGPGSLAAGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEED
Sbjct: 301 SPLPQEGPGSLAAGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEED 360
Query: 361 EEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKEV 420
EEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKEV
Sbjct: 361 EEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKEV 420
Query: 421 TSISSRKRGKRRYFWEYSEQLTPSQQERMLRPSEWNRDTLPSNMYQKNGLHHGKYAVKKS 480
TSISSRKRGKRRYFWEYSEQLTPSQQERMLRPSEWNRDTLPSNMYQKNGLHHGKYAVKKS
Sbjct: 421 TSISSRKRGKRRYFWEYSEQLTPSQQERMLRPSEWNRDTLPSNMYQKNGLHHGKYAVKKS 480
Query: 481 RRTDVEDLTPNPKKLLQIGNELRKLNKVISDLTPVSELPLTARPRSRKEKNKLASRACRL 540
RRTDVEDLTPNPKKLLQIGNELRKLNKVISDLTPVSELPLTARPRSRKEKNKLASRACRL
Sbjct: 481 RRTDVEDLTPNPKKLLQIGNELRKLNKVISDLTPVSELPLTARPRSRKEKNKLASRACRL 540
Query: 541 KKKAQYEANKVKLWGLNTEYGNLLFVINSIKQEIVNRVQNPRDERGPNMGQKLEILIKDT 600
KKKAQYEANKVKLWGLNTEYGNLLFVINSIKQEIVNRVQNPRDERGPNMGQKLEILIKDT
Sbjct: 541 KKKAQYEANKVKLWGLNTEYGNLLFVINSIKQEIVNRVQNPRDERGPNMGQKLEILIKDT 600
Query: 601 LGLPVAGQTSEFVNQVLEKTAEGNPTGGLVGLRIPTSKV 639
LGLPVAGQTSEFVNQVLEKTAEGNPTGGLVGLRIPTSKV
Sbjct: 601 LGLPVAGQTSEFVNQVLEKTAEGNPTGGLVGLRIPTSKV 639
>gi|34482047 adaptor-related protein complex 3, beta 2 subunit [Homo
sapiens]
Length = 1082
Score = 57.0 bits (136), Expect = 5e-08
Identities = 43/164 (26%), Positives = 68/164 (41%), Gaps = 13/164 (7%)
Query: 328 SSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDEEDVDDEDHDE-GFGSEHELSENEEEE 386
S+++K + F SD+ GE S + D E E + D + E G G S+NE+++
Sbjct: 665 SNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQD 724
Query: 387 EEEEDYEDDKDDDISDTFSEPGYENDSVEDLKEVTSISSRKRGKRRYFWEYSEQLTPSQQ 446
E+EE + S+ E G + + SS G ++T +
Sbjct: 725 EDEEKGRGSE----SEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESE 780
Query: 447 ERMLRPSEWNRDTLPSNMYQKNGLHHGKYAVKKSRRTDVEDLTP 490
E L P+ W+R T PS+ A K+ D+ED TP
Sbjct: 781 EEQLEPASWSRKTPPSS--------KSAPATKEISLLDLEDFTP 816
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 55.5 bits (132), Expect = 2e-07
Identities = 53/224 (23%), Positives = 90/224 (40%), Gaps = 39/224 (17%)
Query: 239 KVKINPVQQSRPLLSQIHTDAAKENTCYCGAVAKRQEKKGMEPLQGHATPALPFKETQEL 298
KV ++P ++ + T A K A KK + P + TP +
Sbjct: 63 KVVVSPTKKVA-----VATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKA 117
Query: 299 LLSPLPQEGPGSLAAGESSSLSASTSVSD------SSQKKEEHNYSLFVSDNLGEQPTKC 352
L++ ++G A G + +A SD S + +E+ D + K
Sbjct: 118 LVATPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKA 177
Query: 353 ------SPEEDEEDEEDVDDEDHDEGFGSEHE----------------------LSENEE 384
S +ED+ED+ED +D+D DE SE E ++E+E+
Sbjct: 178 AAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDED 237
Query: 385 EEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKEVTSISSRKR 428
EEE++ED +DD D+D D E E + E+ + V +++
Sbjct: 238 EEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRK 281
Score = 45.1 bits (105), Expect = 2e-04
Identities = 22/70 (31%), Positives = 38/70 (54%)
Query: 355 EEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSV 414
EED+EDE+D DDED ++ + E E EEEEE ++ + +++ + P + V
Sbjct: 239 EEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKV 298
Query: 415 EDLKEVTSIS 424
E + T+ +
Sbjct: 299 EGTEPTTAFN 308
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 55.5 bits (132), Expect = 2e-07
Identities = 40/149 (26%), Positives = 67/149 (44%), Gaps = 15/149 (10%)
Query: 293 KETQELLLSPLPQEGPGSLAAGESS--SLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPT 350
K+ QE P P+ P ++ A SS S D +K+E+ ++
Sbjct: 66 KQPQE----PAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDED 121
Query: 351 KCSPEEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDD---------IS 401
+ E D E+EE++++ED D+ E E EEEEEEEE+ E+++++D I
Sbjct: 122 EEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIM 181
Query: 402 DTFSEPGYENDSVEDLKEVTSISSRKRGK 430
+ ND ++ E+ + S GK
Sbjct: 182 QDTEKDDNNNDEYDNYDELVAKSLLNLGK 210
>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member B [Homo sapiens]
Length = 251
Score = 53.5 bits (127), Expect = 6e-07
Identities = 29/79 (36%), Positives = 47/79 (59%), Gaps = 4/79 (5%)
Query: 355 EEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDD-ISDTFSEPGYENDS 413
+E+EEDEE D+ED D+ G E E +EE++E+ED E D+DDD +S+ E G + +
Sbjct: 166 DEEEEDEEGEDEEDEDDEDGEEEEF---DEEDDEDEDVEGDEDDDEVSEEEEEFGLDEED 222
Query: 414 VEDLKEVTSISSRKRGKRR 432
++ ++ K KR+
Sbjct: 223 EDEDEDEEEEEGGKGEKRK 241
Score = 42.4 bits (98), Expect = 0.001
Identities = 26/83 (31%), Positives = 44/83 (53%), Gaps = 4/83 (4%)
Query: 315 ESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDEEDVD-DEDHDEGF 373
E+ A D ++ EE D GE+ +E+++++EDV+ DED DE
Sbjct: 154 EAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEF---DEEDDEDEDVEGDEDDDEVS 210
Query: 374 GSEHELSENEEEEEEEEDYEDDK 396
E E +EE+E+E+ED E+++
Sbjct: 211 EEEEEFGLDEEDEDEDEDEEEEE 233
Score = 42.4 bits (98), Expect = 0.001
Identities = 26/62 (41%), Positives = 38/62 (61%), Gaps = 5/62 (8%)
Query: 343 DNLGEQPTKCSPEEDEEDEED-VDDEDHD-EGFGSEHELSENEEE---EEEEEDYEDDKD 397
D GE E+ EE+E D DDED D EG + E+SE EEE +EE+ED ++D++
Sbjct: 171 DEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEE 230
Query: 398 DD 399
++
Sbjct: 231 EE 232
Score = 37.7 bits (86), Expect = 0.033
Identities = 20/71 (28%), Positives = 37/71 (52%), Gaps = 6/71 (8%)
Query: 357 DEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVED 416
D ED+E D + +G + E EE+EE E++ ++D +D + F E E++ VE
Sbjct: 149 DREDQEAPDSDAEVDG------VDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEG 202
Query: 417 LKEVTSISSRK 427
++ +S +
Sbjct: 203 DEDDDEVSEEE 213
Score = 32.7 bits (73), Expect = 1.1
Identities = 13/33 (39%), Positives = 22/33 (66%)
Query: 357 DEEDEEDVDDEDHDEGFGSEHELSENEEEEEEE 389
DEEDE++ +DE+ +EG E E ++E E++
Sbjct: 219 DEEDEDEDEDEEEEEGGKGEKRKRETDDEGEDD 251
Score = 31.2 bits (69), Expect = 3.1
Identities = 15/41 (36%), Positives = 22/41 (53%)
Query: 357 DEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKD 397
+EE+E +D+ED DE E E E+ + E D E + D
Sbjct: 211 EEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRETDDEGEDD 251
Score = 30.8 bits (68), Expect = 4.0
Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 4/45 (8%)
Query: 355 EEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDD 399
EE+EE D +DED DE + E E + E+ + + +D+ +DD
Sbjct: 211 EEEEEFGLDEEDEDEDE----DEEEEEGGKGEKRKRETDDEGEDD 251
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 53.1 bits (126), Expect = 8e-07
Identities = 42/150 (28%), Positives = 72/150 (48%), Gaps = 17/150 (11%)
Query: 286 ATPALPFKETQELLLS---------PLPQEGPGSLAAGESSSLSASTSVSDSSQKKEEHN 336
A+P +P KE E L + P P PG + + T EE
Sbjct: 819 ASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDL 878
Query: 337 YSLFVSDNLGEQPTKCSPEEDEEDEEDVDDEDHDEGFGSEHELSEN--EEEEEEEEDYED 394
+ ++ + E+ EE+EE+EE+ ++E+ +E F E E E EEEEEEEE++E+
Sbjct: 879 TVININSSDEEEE-----EEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEE 933
Query: 395 DKDDDISDTFSEPGYEN-DSVEDLKEVTSI 423
+ +++ + E E+ + E+L+EV +
Sbjct: 934 EFEEEEGELEEEEEEEDEEEEEELEEVEDL 963
Score = 43.1 bits (100), Expect = 8e-04
Identities = 35/116 (30%), Positives = 55/116 (47%), Gaps = 9/116 (7%)
Query: 300 LSPLPQEGPGSLAAGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEE 359
L P G G A E + + SD +++EE + E+ + EE+EE
Sbjct: 860 LVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEE----EEEEEEEEEEDFEEEEE 915
Query: 360 DEEDV--DDEDHDEGFGSEHELSENE---EEEEEEEDYEDDKDDDISDTFSEPGYE 410
DEE+ ++E+ +E F E E E E EEEEE+E+ E++ ++ F G E
Sbjct: 916 DEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGE 971
Score = 35.8 bits (81), Expect = 0.12
Identities = 23/80 (28%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 375 SEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKEVTSISSRKRGKRRYF 434
S+ E E EEEEEEEE+ E++++D + E Y + E+ +E + G+
Sbjct: 886 SDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGE---- 941
Query: 435 WEYSEQLTPSQQERMLRPSE 454
E E+ ++E L E
Sbjct: 942 LEEEEEEEDEEEEEELEEVE 961
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 52.8 bits (125), Expect = 1e-06
Identities = 23/59 (38%), Positives = 40/59 (67%)
Query: 355 EEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDS 413
EEDEE+EE+ ++E+ DE E E E EEEEEEEE+ E++++++ + + ++ D+
Sbjct: 259 EEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDT 317
Score = 51.6 bits (122), Expect = 2e-06
Identities = 24/66 (36%), Positives = 40/66 (60%)
Query: 355 EEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSV 414
EE+EE+EE+ +DE+ +E E E E EEEEEEEE+ E+++++ D + + S
Sbjct: 263 EEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSA 322
Query: 415 EDLKEV 420
+ E+
Sbjct: 323 QKAPEL 328
Score = 49.3 bits (116), Expect = 1e-05
Identities = 23/54 (42%), Positives = 35/54 (64%)
Query: 347 EQPTKCSPEEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDI 400
E+ + EE+EE+EED ++E+ +E E E E EEEEEEEE+ E++ D+
Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDV 311
Score = 47.4 bits (111), Expect = 4e-05
Identities = 35/131 (26%), Positives = 60/131 (45%), Gaps = 3/131 (2%)
Query: 282 LQGHATPALPFKETQELLLSPLPQEGPGSLAAGESSSLSASTSVSDSSQKKEEHNYSLFV 341
LQ A A + + L + P E + S L S+ D++ ++ +
Sbjct: 198 LQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQ-SLEDAASEESSKQKGILS 256
Query: 342 SDNLGEQPTKCSPEEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDK--DDD 399
+ E+ + EE+E++EE+ ++E+ +E E E E EEEEEEEE+ D +D
Sbjct: 257 HEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQED 316
Query: 400 ISDTFSEPGYE 410
S T ++ E
Sbjct: 317 TSHTSAQKAPE 327
Score = 41.2 bits (95), Expect = 0.003
Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 5/92 (5%)
Query: 333 EEHNYSLFVSDNLGEQPTKCSPEEDEE----DEEDVDDEDHDEGFGS-EHELSENEEEEE 387
EE LF+ E+ + + E ++ ED E+ + G HE + EEEEE
Sbjct: 208 EEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEE 267
Query: 388 EEEDYEDDKDDDISDTFSEPGYENDSVEDLKE 419
EEE+ ED+++++ + E E + E+ +E
Sbjct: 268 EEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEE 299
Score = 39.3 bits (90), Expect = 0.011
Identities = 20/66 (30%), Positives = 35/66 (53%)
Query: 355 EEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSV 414
EE + + + E+ DE E E E +EEEEEEE+ E++++++ + E E +
Sbjct: 246 EESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 305
Query: 415 EDLKEV 420
E +V
Sbjct: 306 EAAPDV 311
Score = 37.7 bits (86), Expect = 0.033
Identities = 21/75 (28%), Positives = 40/75 (53%), Gaps = 13/75 (17%)
Query: 342 SDNLGEQPTKCSPEEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDIS 401
S+ +Q S EE++E+EE+ ++E E E+EEEEEE+ E++++++
Sbjct: 245 SEESSKQKGILSHEEEDEEEEEEEEE-------------EEEDEEEEEEEEEEEEEEEEE 291
Query: 402 DTFSEPGYENDSVED 416
+ E E + E+
Sbjct: 292 EEEEEEEEEEEEEEE 306
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 52.8 bits (125), Expect = 1e-06
Identities = 42/172 (24%), Positives = 70/172 (40%), Gaps = 34/172 (19%)
Query: 305 QEGPGSLAAGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEE----- 359
+E P + ++G+ L STSV + ++ E ++ + P + + + +
Sbjct: 967 KEPPDTTSSGDQKRLRPSTSVDEEDEESERER-----DRDMADTPCELAKRDPKGVGVRR 1021
Query: 360 ------DEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISD----------- 402
+ + +ED E E E +E EEE EEEE+ EDD DDD D
Sbjct: 1022 RPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDT 1081
Query: 403 TFSEPGYENDSVEDLKEVTSI-------SSRKRGKRRYFWEYSEQLTPSQQE 447
SE +++ D +E SI +S +E S + +PS E
Sbjct: 1082 ALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSE 1133
Score = 35.0 bits (79), Expect = 0.21
Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
Query: 315 ESSSLSASTSVSDSSQKKE-EHNYSLFVSDNLGEQPTKCSPEEDEEDEEDVDDEDHDEGF 373
ES + T++S++S+K E + + VS + S E E E + E
Sbjct: 1073 ESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSS 1132
Query: 374 GSEHELSENEEEEEEEED 391
E E+ EEEEEEEE+
Sbjct: 1133 EDEEEVVAREEEEEEEEE 1150
Score = 32.3 bits (72), Expect = 1.4
Identities = 25/105 (23%), Positives = 47/105 (44%), Gaps = 9/105 (8%)
Query: 294 ETQELLLSPLPQEGPGSLAAGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCS 353
+ ++ LS ++ G + E ++S TS ++++ E S F E ++ S
Sbjct: 1077 DDEDTALSEASEKDEGD--SDEEETVSIVTSKAEATSSSESSESSEF------ESSSESS 1128
Query: 354 PEEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDD 398
P EDEE+V + +E E ++E ED+E D ++
Sbjct: 1129 PSSS-EDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEE 1172
Score = 29.6 bits (65), Expect = 8.9
Identities = 28/123 (22%), Positives = 49/123 (39%), Gaps = 22/123 (17%)
Query: 312 AAGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDEEDVDDED--- 368
+ GE + + +S++++EE ++ E+ + D+ DE + DDED
Sbjct: 1031 SGGEEDEKESLSEEQESTEEEEE-------AEEEEEEEDDDDDDSDDRDESENDDEDTAL 1083
Query: 369 -----HDEGFGSEHEL-------SENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVED 416
DEG E E +E E E E + + S + SE E + E+
Sbjct: 1084 SEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREE 1143
Query: 417 LKE 419
+E
Sbjct: 1144 EEE 1146
>gi|33946282 hypothetical protein LOC25962 isoform 1 [Homo sapiens]
Length = 1812
Score = 52.4 bits (124), Expect = 1e-06
Identities = 53/183 (28%), Positives = 79/183 (43%), Gaps = 19/183 (10%)
Query: 244 PVQQSRPLLSQI--HTDAAKENTCYCGAVAKRQEKKGMEPLQGHATPALPFKETQELLLS 301
P Q +P L + H D KE+ + G+ + Q + P P P + E
Sbjct: 147 PPPQPQPSLKRNPKHADGEKEDQ-FNGSPPRPQPRGPRTP------PGPPPPDDDEDDPV 199
Query: 302 PLPQEGPGSLAAGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDE 361
PLP G A S D + +E YS + GE + EE EEDE
Sbjct: 200 PLPVSGDKEEDAPHREDYFEPIS-PDRNSVPQEGQYS-----DEGEVEEE-QQEEGEEDE 252
Query: 362 EDVD---DEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLK 418
+DVD +ED DE + EEEE+EEE+ E+D++ + D + + + D + DL+
Sbjct: 253 DDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLE 312
Query: 419 EVT 421
T
Sbjct: 313 RET 315
Score = 35.8 bits (81), Expect = 0.12
Identities = 38/150 (25%), Positives = 63/150 (42%), Gaps = 28/150 (18%)
Query: 281 PLQGHATPALPFKETQELLLSP----LPQEGPGSLAAGESSSLSASTSVSDSSQKKEEHN 336
P+ G P +E +SP +PQEG S V + Q++ E +
Sbjct: 202 PVSGDKEEDAPHREDYFEPISPDRNSVPQEG----------QYSDEGEVEEEQQEEGEED 251
Query: 337 YSLFVSDNLGEQPTKCSPEEDEEDEEDVD-----DEDHDEGFGSEHELSENEEEEEEEED 391
D++ + + +EDE+D VD +E+ +E G E E E ++ E+
Sbjct: 252 -----EDDVDVEEEE---DEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISS 303
Query: 392 YEDDKDDDISDTFSEPGYEND-SVEDLKEV 420
ED D +TF P ++ + + EDL V
Sbjct: 304 DEDGIADLERETFKYPNFDVEYTAEDLASV 333
Score = 30.4 bits (67), Expect = 5.2
Identities = 24/97 (24%), Positives = 40/97 (41%), Gaps = 20/97 (20%)
Query: 354 PEEDEED----------EEDVDD-EDHDEGFGSEHELSENE---------EEEEEEEDYE 393
P++DE+D EED ED+ E + E EEE++EE E
Sbjct: 191 PDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEE 250
Query: 394 DDKDDDISDTFSEPGYENDSVEDLKEVTSISSRKRGK 430
D+ D D+ + E + +V+ + E + G+
Sbjct: 251 DEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGE 287
>gi|33946280 hypothetical protein LOC25962 isoform 2 [Homo sapiens]
Length = 1147
Score = 52.4 bits (124), Expect = 1e-06
Identities = 53/183 (28%), Positives = 79/183 (43%), Gaps = 19/183 (10%)
Query: 244 PVQQSRPLLSQI--HTDAAKENTCYCGAVAKRQEKKGMEPLQGHATPALPFKETQELLLS 301
P Q +P L + H D KE+ + G+ + Q + P P P + E
Sbjct: 147 PPPQPQPSLKRNPKHADGEKEDQ-FNGSPPRPQPRGPRTP------PGPPPPDDDEDDPV 199
Query: 302 PLPQEGPGSLAAGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDE 361
PLP G A S D + +E YS + GE + EE EEDE
Sbjct: 200 PLPVSGDKEEDAPHREDYFEPIS-PDRNSVPQEGQYS-----DEGEVEEE-QQEEGEEDE 252
Query: 362 EDVD---DEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLK 418
+DVD +ED DE + EEEE+EEE+ E+D++ + D + + + D + DL+
Sbjct: 253 DDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLE 312
Query: 419 EVT 421
T
Sbjct: 313 RET 315
Score = 35.8 bits (81), Expect = 0.12
Identities = 38/150 (25%), Positives = 63/150 (42%), Gaps = 28/150 (18%)
Query: 281 PLQGHATPALPFKETQELLLSP----LPQEGPGSLAAGESSSLSASTSVSDSSQKKEEHN 336
P+ G P +E +SP +PQEG S V + Q++ E +
Sbjct: 202 PVSGDKEEDAPHREDYFEPISPDRNSVPQEG----------QYSDEGEVEEEQQEEGEED 251
Query: 337 YSLFVSDNLGEQPTKCSPEEDEEDEEDVD-----DEDHDEGFGSEHELSENEEEEEEEED 391
D++ + + +EDE+D VD +E+ +E G E E E ++ E+
Sbjct: 252 -----EDDVDVEEEE---DEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISS 303
Query: 392 YEDDKDDDISDTFSEPGYEND-SVEDLKEV 420
ED D +TF P ++ + + EDL V
Sbjct: 304 DEDGIADLERETFKYPNFDVEYTAEDLASV 333
Score = 30.4 bits (67), Expect = 5.2
Identities = 24/97 (24%), Positives = 40/97 (41%), Gaps = 20/97 (20%)
Query: 354 PEEDEED----------EEDVDD-EDHDEGFGSEHELSENE---------EEEEEEEDYE 393
P++DE+D EED ED+ E + E EEE++EE E
Sbjct: 191 PDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEE 250
Query: 394 DDKDDDISDTFSEPGYENDSVEDLKEVTSISSRKRGK 430
D+ D D+ + E + +V+ + E + G+
Sbjct: 251 DEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGE 287
>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
Length = 740
Score = 52.0 bits (123), Expect = 2e-06
Identities = 36/123 (29%), Positives = 59/123 (47%), Gaps = 8/123 (6%)
Query: 310 SLAAGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDEEDVDDEDH 369
SL +GE S AS +S+ + + D E+ + EE+EE+EE+ D +
Sbjct: 412 SLDSGEGPSGMASQGCPSASRAETD--------DEDDEESDEEEEEEEEEEEEEATDSEE 463
Query: 370 DEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKEVTSISSRKRG 429
+E E E++EEE+EEE+ KD D S S ++E K+++ S ++
Sbjct: 464 EEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQN 523
Query: 430 KRR 432
K R
Sbjct: 524 KGR 526
Score = 42.4 bits (98), Expect = 0.001
Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 9/92 (9%)
Query: 328 SSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDEEDVDDEDHDEGFGSEHELSENEEEEE 387
SS + SL + ++ P + +D DDE+ DE E EEEEE
Sbjct: 402 SSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDE--------EEEEEEEE 453
Query: 388 EEEDYEDDKDDDISDTFSEPGYENDSVEDLKE 419
EEE+ D ++++ + E G E+D ED +E
Sbjct: 454 EEEEATDSEEEEDLEQMQE-GQEDDEEEDEEE 484
Score = 29.6 bits (65), Expect = 8.9
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 11/105 (10%)
Query: 274 QEKKGMEPLQGHATPALPFKETQELLLSPLPQEGPGSLAAGESSSLSASTS------VSD 327
+ KK LQG ++ + +T E L EGP +A+ S S + + SD
Sbjct: 390 ERKKRRARLQGTSSHSA---DTPEASLDS--GEGPSGMASQGCPSASRAETDDEDDEESD 444
Query: 328 SSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDEEDVDDEDHDEG 372
+++EE +D+ E+ + E E+DEE+ ++E+ G
Sbjct: 445 EEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAG 489
>gi|215422388 death-domain associated protein isoform a [Homo
sapiens]
Length = 740
Score = 52.0 bits (123), Expect = 2e-06
Identities = 36/123 (29%), Positives = 59/123 (47%), Gaps = 8/123 (6%)
Query: 310 SLAAGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDEEDVDDEDH 369
SL +GE S AS +S+ + + D E+ + EE+EE+EE+ D +
Sbjct: 412 SLDSGEGPSGMASQGCPSASRAETD--------DEDDEESDEEEEEEEEEEEEEATDSEE 463
Query: 370 DEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKEVTSISSRKRG 429
+E E E++EEE+EEE+ KD D S S ++E K+++ S ++
Sbjct: 464 EEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQN 523
Query: 430 KRR 432
K R
Sbjct: 524 KGR 526
Score = 42.4 bits (98), Expect = 0.001
Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 9/92 (9%)
Query: 328 SSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDEEDVDDEDHDEGFGSEHELSENEEEEE 387
SS + SL + ++ P + +D DDE+ DE E EEEEE
Sbjct: 402 SSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDE--------EEEEEEEE 453
Query: 388 EEEDYEDDKDDDISDTFSEPGYENDSVEDLKE 419
EEE+ D ++++ + E G E+D ED +E
Sbjct: 454 EEEEATDSEEEEDLEQMQE-GQEDDEEEDEEE 484
Score = 29.6 bits (65), Expect = 8.9
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 11/105 (10%)
Query: 274 QEKKGMEPLQGHATPALPFKETQELLLSPLPQEGPGSLAAGESSSLSASTS------VSD 327
+ KK LQG ++ + +T E L EGP +A+ S S + + SD
Sbjct: 390 ERKKRRARLQGTSSHSA---DTPEASLDS--GEGPSGMASQGCPSASRAETDDEDDEESD 444
Query: 328 SSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDEEDVDDEDHDEG 372
+++EE +D+ E+ + E E+DEE+ ++E+ G
Sbjct: 445 EEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAG 489
>gi|215422366 death-domain associated protein isoform b [Homo
sapiens]
Length = 752
Score = 52.0 bits (123), Expect = 2e-06
Identities = 36/123 (29%), Positives = 59/123 (47%), Gaps = 8/123 (6%)
Query: 310 SLAAGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDEEDVDDEDH 369
SL +GE S AS +S+ + + D E+ + EE+EE+EE+ D +
Sbjct: 424 SLDSGEGPSGMASQGCPSASRAETD--------DEDDEESDEEEEEEEEEEEEEATDSEE 475
Query: 370 DEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKEVTSISSRKRG 429
+E E E++EEE+EEE+ KD D S S ++E K+++ S ++
Sbjct: 476 EEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQN 535
Query: 430 KRR 432
K R
Sbjct: 536 KGR 538
Score = 42.4 bits (98), Expect = 0.001
Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 9/92 (9%)
Query: 328 SSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDEEDVDDEDHDEGFGSEHELSENEEEEE 387
SS + SL + ++ P + +D DDE+ DE E EEEEE
Sbjct: 414 SSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDE--------EEEEEEEE 465
Query: 388 EEEDYEDDKDDDISDTFSEPGYENDSVEDLKE 419
EEE+ D ++++ + E G E+D ED +E
Sbjct: 466 EEEEATDSEEEEDLEQMQE-GQEDDEEEDEEE 496
Score = 29.6 bits (65), Expect = 8.9
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 11/105 (10%)
Query: 274 QEKKGMEPLQGHATPALPFKETQELLLSPLPQEGPGSLAAGESSSLSASTS------VSD 327
+ KK LQG ++ + +T E L EGP +A+ S S + + SD
Sbjct: 402 ERKKRRARLQGTSSHSA---DTPEASLDS--GEGPSGMASQGCPSASRAETDDEDDEESD 456
Query: 328 SSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDEEDVDDEDHDEG 372
+++EE +D+ E+ + E E+DEE+ ++E+ G
Sbjct: 457 EEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAG 501
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 51.6 bits (122), Expect = 2e-06
Identities = 51/181 (28%), Positives = 77/181 (42%), Gaps = 22/181 (12%)
Query: 236 KKAKVKINPVQQSRPLLSQIHTDAAKENTCYCGAVAKRQEKKGMEPLQGHATPALPFKET 295
KK K + PV ++++ TD E Y Q+ G QG TP +ET
Sbjct: 1857 KKLK-SVTPVGTEEEVMAEESTDGEVETQVYN---QDSQDSIGEGVTQGDYTPMEDSEET 1912
Query: 296 QELL---LSPLPQEGPGSLAAGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKC 352
+ L L PL + + ++ + V DS ++E+ + +N GE
Sbjct: 1913 SQSLQIDLGPLQSDQQTTTSSQDGQGKGDDVIVIDSDDEEEDDD------ENDGEH---- 1962
Query: 353 SPEEDEEDEEDVDDEDHDEGFGSEHELS-ENEEEEEEEEDYEDDKDDDISDTFSEPGYEN 411
E+ EEDEED DD++ D G G E E S E + + YE DD ++PG E
Sbjct: 1963 --EDYEEDEEDDDDDEDDTGMGDEGEDSNEGTGSADGNDGYE--ADDAEGGDGTDPGTET 2018
Query: 412 D 412
+
Sbjct: 2019 E 2019
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 51.2 bits (121), Expect = 3e-06
Identities = 50/196 (25%), Positives = 82/196 (41%), Gaps = 19/196 (9%)
Query: 315 ESSSLSASTSVSDSSQ-KKEEHNYSLFVSDNLGEQPTKCSPEEDEEDEEDVDDEDHDEGF 373
+SSS+S SD + +K E S + P E+EED+E +
Sbjct: 205 KSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQET---PSRNLRV 261
Query: 374 GSEHELSENEEEEEEEEDYEDDKDDDISD------------TFSEPGYENDSVEDLKEVT 421
++ L EEEEEEEE+ EDD++++ D F E G E V+ +E+
Sbjct: 262 RADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKP-EEMM 320
Query: 422 SISSRKRGKRRYFWEYSEQLTPSQQERMLRPSEWNRDTLPSNMYQKNGLHHGKYAVKKSR 481
+ R + + E + T SQ+E R S R M + L + +K S+
Sbjct: 321 DERPKTRSQEQEVLERGGRFTRSQEE--ARKSHLARQQQEKEMKTTSPLEEEEREIKSSQ 378
Query: 482 RTDVEDLTPNPKKLLQ 497
+ +P+P +L +
Sbjct: 379 GLKEKSKSPSPPRLTE 394
Score = 30.4 bits (67), Expect = 5.2
Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 17/90 (18%)
Query: 357 DEEDEEDVDDEDHDEGFGS--------EHELSENEEEEEEEEDYEDDKDDDISDTFS-EP 407
++E E + DD HD+G E EN + EEEEE+ E + + + S E
Sbjct: 899 EDETERNGDDGTHDKGLKICRTVTQVVPAEGQENGQREEEEEEKEPEAEPPVPPQVSVEV 958
Query: 408 GYENDSVEDLKEVT--------SISSRKRG 429
+ ++K+VT SIS +K G
Sbjct: 959 ALPPPAEHEVKKVTLGDTLTRRSISQQKSG 988
>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member E isoform 1 [Homo sapiens]
Length = 268
Score = 50.8 bits (120), Expect = 4e-06
Identities = 25/55 (45%), Positives = 36/55 (65%), Gaps = 2/55 (3%)
Query: 347 EQPTKCSPEEDEEDEED--VDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDD 399
+Q +P+ +EED+ED DDE+ +E E E EEEEEEEED ++D+D+D
Sbjct: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDED 203
Score = 47.4 bits (111), Expect = 4e-05
Identities = 21/54 (38%), Positives = 32/54 (59%)
Query: 353 SPEEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSE 406
S EED+ED ++ D+E+ + G E EEEEEEE++ ED+ +D+ E
Sbjct: 158 SEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGE 211
Score = 41.6 bits (96), Expect = 0.002
Identities = 29/98 (29%), Positives = 48/98 (48%), Gaps = 10/98 (10%)
Query: 326 SDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDEEDVDDEDHDEGFGSEHELSENEEE 385
+++ +EE + D E+ PE EE+EE+ ++ED DE + SE E
Sbjct: 153 NEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEG 212
Query: 386 EEE-------EEDYEDDKDDDISDTFSEPGYENDSVED 416
EEE +E+ +D++DD D + E G E + E+
Sbjct: 213 EEEVGLSYLMKEEIQDEEDD---DDYVEEGEEEEEEEE 247
Score = 38.1 bits (87), Expect = 0.025
Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 12/63 (19%)
Query: 357 DEEDEEDVDDEDHDEGFGSEHELSENEEEE---------EEEEDYEDDKDDDISDTFSEP 407
D+ED E D E+ D+ G E + EEEE EEEE+ E+++D+D + E
Sbjct: 149 DQEDNEAPDSEEEDDEDGDE---DDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 205
Query: 408 GYE 410
G E
Sbjct: 206 GSE 208
Score = 36.6 bits (83), Expect = 0.073
Identities = 15/49 (30%), Positives = 30/49 (61%)
Query: 371 EGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKE 419
+GF E + + EEE++E+ EDD++++ ++ GYE + E+ +E
Sbjct: 146 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEE 194
Score = 35.0 bits (79), Expect = 0.21
Identities = 31/92 (33%), Positives = 38/92 (41%), Gaps = 35/92 (38%)
Query: 343 DNLGEQPTKCSPEEDEEDEEDVD-DEDHDE-----GFGSEHE------------------ 378
+N P EE+EE+EED D DED DE G G E
Sbjct: 175 ENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDD 234
Query: 379 -LSENEEEEEEEE----------DYEDDKDDD 399
+ E EEEEEEEE D EDD +++
Sbjct: 235 YVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEE 266
Score = 29.6 bits (65), Expect = 8.9
Identities = 13/42 (30%), Positives = 24/42 (57%)
Query: 356 EDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKD 397
+DEED++D +E +E E L + + + E+D E++ D
Sbjct: 227 QDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 268
>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 2 [Homo sapiens]
Length = 227
Score = 50.8 bits (120), Expect = 4e-06
Identities = 25/55 (45%), Positives = 36/55 (65%), Gaps = 2/55 (3%)
Query: 347 EQPTKCSPEEDEEDEED--VDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDD 399
+Q +P+ +EED+ED DDE+ +E E E EEEEEEEED ++D+D+D
Sbjct: 108 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDED 162
Score = 47.4 bits (111), Expect = 4e-05
Identities = 21/54 (38%), Positives = 32/54 (59%)
Query: 353 SPEEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSE 406
S EED+ED ++ D+E+ + G E EEEEEEE++ ED+ +D+ E
Sbjct: 117 SEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGE 170
Score = 41.6 bits (96), Expect = 0.002
Identities = 29/98 (29%), Positives = 48/98 (48%), Gaps = 10/98 (10%)
Query: 326 SDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDEEDVDDEDHDEGFGSEHELSENEEE 385
+++ +EE + D E+ PE EE+EE+ ++ED DE + SE E
Sbjct: 112 NEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEG 171
Query: 386 EEE-------EEDYEDDKDDDISDTFSEPGYENDSVED 416
EEE +E+ +D++DD D + E G E + E+
Sbjct: 172 EEEVGLSYLMKEEIQDEEDD---DDYVEEGEEEEEEEE 206
Score = 38.1 bits (87), Expect = 0.025
Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 12/63 (19%)
Query: 357 DEEDEEDVDDEDHDEGFGSEHELSENEEEE---------EEEEDYEDDKDDDISDTFSEP 407
D+ED E D E+ D+ G E + EEEE EEEE+ E+++D+D + E
Sbjct: 108 DQEDNEAPDSEEEDDEDGDE---DDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 164
Query: 408 GYE 410
G E
Sbjct: 165 GSE 167
Score = 36.6 bits (83), Expect = 0.073
Identities = 15/49 (30%), Positives = 30/49 (61%)
Query: 371 EGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKE 419
+GF E + + EEE++E+ EDD++++ ++ GYE + E+ +E
Sbjct: 105 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEE 153
Score = 35.0 bits (79), Expect = 0.21
Identities = 31/92 (33%), Positives = 38/92 (41%), Gaps = 35/92 (38%)
Query: 343 DNLGEQPTKCSPEEDEEDEEDVD-DEDHDE-----GFGSEHE------------------ 378
+N P EE+EE+EED D DED DE G G E
Sbjct: 134 ENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDD 193
Query: 379 -LSENEEEEEEEE----------DYEDDKDDD 399
+ E EEEEEEEE D EDD +++
Sbjct: 194 YVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEE 225
Score = 29.6 bits (65), Expect = 8.9
Identities = 13/42 (30%), Positives = 24/42 (57%)
Query: 356 EDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKD 397
+DEED++D +E +E E L + + + E+D E++ D
Sbjct: 186 QDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 227
>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 3 [Homo sapiens]
Length = 220
Score = 50.8 bits (120), Expect = 4e-06
Identities = 25/55 (45%), Positives = 36/55 (65%), Gaps = 2/55 (3%)
Query: 347 EQPTKCSPEEDEEDEED--VDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDD 399
+Q +P+ +EED+ED DDE+ +E E E EEEEEEEED ++D+D+D
Sbjct: 101 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDED 155
Score = 47.4 bits (111), Expect = 4e-05
Identities = 21/54 (38%), Positives = 32/54 (59%)
Query: 353 SPEEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSE 406
S EED+ED ++ D+E+ + G E EEEEEEE++ ED+ +D+ E
Sbjct: 110 SEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGE 163
Score = 41.6 bits (96), Expect = 0.002
Identities = 29/98 (29%), Positives = 48/98 (48%), Gaps = 10/98 (10%)
Query: 326 SDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDEEDVDDEDHDEGFGSEHELSENEEE 385
+++ +EE + D E+ PE EE+EE+ ++ED DE + SE E
Sbjct: 105 NEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEG 164
Query: 386 EEE-------EEDYEDDKDDDISDTFSEPGYENDSVED 416
EEE +E+ +D++DD D + E G E + E+
Sbjct: 165 EEEVGLSYLMKEEIQDEEDD---DDYVEEGEEEEEEEE 199
Score = 38.1 bits (87), Expect = 0.025
Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 12/63 (19%)
Query: 357 DEEDEEDVDDEDHDEGFGSEHELSENEEEE---------EEEEDYEDDKDDDISDTFSEP 407
D+ED E D E+ D+ G E + EEEE EEEE+ E+++D+D + E
Sbjct: 101 DQEDNEAPDSEEEDDEDGDE---DDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 157
Query: 408 GYE 410
G E
Sbjct: 158 GSE 160
Score = 36.6 bits (83), Expect = 0.073
Identities = 15/49 (30%), Positives = 30/49 (61%)
Query: 371 EGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKE 419
+GF E + + EEE++E+ EDD++++ ++ GYE + E+ +E
Sbjct: 98 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEE 146
Score = 35.0 bits (79), Expect = 0.21
Identities = 31/92 (33%), Positives = 38/92 (41%), Gaps = 35/92 (38%)
Query: 343 DNLGEQPTKCSPEEDEEDEEDVD-DEDHDE-----GFGSEHE------------------ 378
+N P EE+EE+EED D DED DE G G E
Sbjct: 127 ENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDD 186
Query: 379 -LSENEEEEEEEE----------DYEDDKDDD 399
+ E EEEEEEEE D EDD +++
Sbjct: 187 YVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEE 218
Score = 29.6 bits (65), Expect = 8.9
Identities = 13/42 (30%), Positives = 24/42 (57%)
Query: 356 EDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKD 397
+DEED++D +E +E E L + + + E+D E++ D
Sbjct: 179 QDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 220
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 50.8 bits (120), Expect = 4e-06
Identities = 35/112 (31%), Positives = 56/112 (50%), Gaps = 23/112 (20%)
Query: 314 GESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDEEDVDDEDHDEGF 373
G S + +S DS++ +EE +++EEDEED +D++ D+
Sbjct: 593 GTDSDIPSSKDSEDSNEDEEE--------------------DDEEEDEEDDEDDESDDSQ 632
Query: 374 GSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKEVTSISS 425
SE++ E EEED +DDKD D SD+ +E E S++ K +S+ S
Sbjct: 633 SESDSNSESDTEGSEEED-DDDKDQDESDSDTEG--EKTSMKLNKTTSSVKS 681
Score = 43.5 bits (101), Expect = 6e-04
Identities = 34/123 (27%), Positives = 49/123 (39%), Gaps = 12/123 (9%)
Query: 301 SPLPQEGPGSLAAGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLG-------EQPTKCS 353
SP+ G G + + S S SQ KE+ VS+N+ P K
Sbjct: 533 SPVNLSTSGRRTPGNQTPVMPSASPILHSQGKEKA-----VSNNVNPVKTQHHSHPAKSL 587
Query: 354 PEEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDS 413
E+ + D+ E + E + EE+EE++ED E D SD+ SE E
Sbjct: 588 VEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSE 647
Query: 414 VED 416
ED
Sbjct: 648 EED 650
Score = 42.7 bits (99), Expect = 0.001
Identities = 31/105 (29%), Positives = 55/105 (52%), Gaps = 12/105 (11%)
Query: 344 NLGEQ------PTKCSPEEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKD 397
+LGE+ PT + + D DD+D D+ S+ + E++E+EE++ED + K
Sbjct: 1273 DLGEEQHPLGTPTPGRKRRRKGGDSDYDDDDDDD---SDDQGDEDDEDEEDKEDKKGKKT 1329
Query: 398 DDISDTFSEPGYENDSVEDL-KEVTSISSRKRGKRRYFWEYSEQL 441
D D + G + SVE+L K++ +S ++ RR ++ S L
Sbjct: 1330 DICED--EDEGDQAASVEELEKQIEKLSKQQSQYRRKLFDASHSL 1372
Score = 34.3 bits (77), Expect = 0.36
Identities = 29/111 (26%), Positives = 52/111 (46%), Gaps = 8/111 (7%)
Query: 310 SLAAGESSSLSASTSVSDSSQK---KEEHNYSLF--VSDNLGEQPTKCSPEEDEEDEED- 363
S A S + STS ++K ++ N L V ++P K + E + D
Sbjct: 190 STTASSSMGQTKSTSSGGGNRKCNQEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDS 249
Query: 364 -VDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDS 413
+ EG S + + EE+EEEE+ ++ +DD SD+ SE +++++
Sbjct: 250 GTSSDTSSEGISSS-DSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNN 299
Score = 33.9 bits (76), Expect = 0.47
Identities = 17/80 (21%), Positives = 39/80 (48%)
Query: 356 EDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVE 415
+D+ DE+D D+ED ++ G + ++ E+E+E ++ E+ + + + Y +
Sbjct: 1308 DDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAASVEELEKQIEKLSKQQSQYRRKLFD 1367
Query: 416 DLKEVTSISSRKRGKRRYFW 435
+ S+ + RR +W
Sbjct: 1368 ASHSLRSVMFGQDRYRRRYW 1387
Score = 30.8 bits (68), Expect = 4.0
Identities = 59/244 (24%), Positives = 97/244 (39%), Gaps = 32/244 (13%)
Query: 313 AGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDEEDVDDEDHDEG 372
A ESSS S S S + S E S SD+L EEDEE+E+ +E D+
Sbjct: 238 AMESSSNSDSDSGTSSDTSSE--GISSSDSDDL---------EEDEEEEDQSIEESEDDD 286
Query: 373 FGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKEVTSISSRK-RGKR 431
SE E + D K D T E E + L + + + ++
Sbjct: 287 SDSESEAQHKSNNQVLLHGISDPKADGQKAT--EKAQEKRIHQPLPLASESQTHSFQSQQ 344
Query: 432 RYFWEYSEQLTPSQQERMLRPSEWNRDTLPSNMYQKNGLHHG----KYAVKKSRRTDVED 487
+ S+QL Q + N+ T ++ Q GL + + T ++
Sbjct: 345 KQPQVLSQQLPFIFQSSQAKEESVNKHT---SVIQSTGLVSNVKPLSLVNQAKKETYMKL 401
Query: 488 LTPNPKKLLQIGNELRKLNKVISDLTPVSELPLTARPRSRKEKNKLASRACRLKKKAQYE 547
+ P+P +L+ GN+ + + S L LT+ RS++E+ K A + K+++
Sbjct: 402 IVPSP-DVLKAGNK---------NTSEESSL-LTSELRSKREQYKQAFPSQLKKQESSKS 450
Query: 548 ANKV 551
KV
Sbjct: 451 LKKV 454
>gi|156071452 nardilysin isoform b [Homo sapiens]
Length = 1151
Score = 50.4 bits (119), Expect = 5e-06
Identities = 31/112 (27%), Positives = 59/112 (52%), Gaps = 7/112 (6%)
Query: 309 GSLA-AGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDEEDVDDE 367
GSL+ AG+ + + + K ++ + +L K D+E+EE+V++E
Sbjct: 93 GSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEE 152
Query: 368 DHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKE 419
+ D+ S E+ +++EE ++ED DD+ DD DT E++ +E+L+E
Sbjct: 153 EEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDT------EDNELEELEE 198
>gi|156071450 nardilysin isoform a [Homo sapiens]
Length = 1219
Score = 50.4 bits (119), Expect = 5e-06
Identities = 31/112 (27%), Positives = 59/112 (52%), Gaps = 7/112 (6%)
Query: 309 GSLA-AGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDEEDVDDE 367
GSL+ AG+ + + + K ++ + +L K D+E+EE+V++E
Sbjct: 93 GSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEE 152
Query: 368 DHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKE 419
+ D+ S E+ +++EE ++ED DD+ DD DT E++ +E+L+E
Sbjct: 153 EEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDT------EDNELEELEE 198
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 50.1 bits (118), Expect = 6e-06
Identities = 40/117 (34%), Positives = 52/117 (44%), Gaps = 17/117 (14%)
Query: 317 SSLSASTSVSDSSQKKEEHNYSLFVSDNLG------EQPTKCSPEEDEEDEEDVDDE--- 367
SS S+ V+ + S SD G E+ + EEDEE EED +++
Sbjct: 166 SSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEV 225
Query: 368 DHDEGFGSEHELSENEEEEEEEEDYEDDKDD--------DISDTFSEPGYENDSVED 416
D D E E E EEEEEEEE+YE D+ D D S+ G E+ S D
Sbjct: 226 DEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTD 282
Score = 48.1 bits (113), Expect = 2e-05
Identities = 36/120 (30%), Positives = 57/120 (47%), Gaps = 13/120 (10%)
Query: 315 ESSSLSASTSVSDSSQK-KEEHNYSLFVSDN-------LGEQPTKCSPEEDEEDEEDVDD 366
E L S SSQ KEE N + SD+ EQ EE+ +E+ +D
Sbjct: 153 ERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEED 212
Query: 367 EDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKEVTSISSR 426
E+ +E + E+ E+ EEEEEEE+ E++++++ E YE D + +E +R
Sbjct: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEE-----EEEEYEQDERDQKEEGNDYDTR 267
Score = 37.4 bits (85), Expect = 0.043
Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 11/89 (12%)
Query: 342 SDNLGEQPTKCSPEEDEEDEEDVDDE----DHDEGF-GSEHELSENEEEEEE--EEDYED 394
S+ +G + + + + +E+V+ E DH+ G GS E N E EEE EED E+
Sbjct: 152 SERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEE 211
Query: 395 D----KDDDISDTFSEPGYENDSVEDLKE 419
D +D + + E G E + E+ +E
Sbjct: 212 DEEVEEDAEEDEEVDEDGEEEEEEEEEEE 240
Score = 37.0 bits (84), Expect = 0.056
Identities = 23/87 (26%), Positives = 45/87 (51%), Gaps = 7/87 (8%)
Query: 347 EQPTKCSPEEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSE 406
E+ + EE+EE+EE+ ++E+ +E E E +E +++EE + D + SD+ SE
Sbjct: 223 EEVDEDGEEEEEEEEEEEEEEEEEE------EEYEQDERDQKEEGNDYDTRSEASDSGSE 276
Query: 407 P-GYENDSVEDLKEVTSISSRKRGKRR 432
+ + SV +K+ ++R
Sbjct: 277 SVSFTDGSVRSGSGTDGSDEKKKERKR 303
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 50.1 bits (118), Expect = 6e-06
Identities = 40/117 (34%), Positives = 52/117 (44%), Gaps = 17/117 (14%)
Query: 317 SSLSASTSVSDSSQKKEEHNYSLFVSDNLG------EQPTKCSPEEDEEDEEDVDDE--- 367
SS S+ V+ + S SD G E+ + EEDEE EED +++
Sbjct: 166 SSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEV 225
Query: 368 DHDEGFGSEHELSENEEEEEEEEDYEDDKDD--------DISDTFSEPGYENDSVED 416
D D E E E EEEEEEEE+YE D+ D D S+ G E+ S D
Sbjct: 226 DEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTD 282
Score = 48.1 bits (113), Expect = 2e-05
Identities = 36/120 (30%), Positives = 57/120 (47%), Gaps = 13/120 (10%)
Query: 315 ESSSLSASTSVSDSSQK-KEEHNYSLFVSDN-------LGEQPTKCSPEEDEEDEEDVDD 366
E L S SSQ KEE N + SD+ EQ EE+ +E+ +D
Sbjct: 153 ERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEED 212
Query: 367 EDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKEVTSISSR 426
E+ +E + E+ E+ EEEEEEE+ E++++++ E YE D + +E +R
Sbjct: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEE-----EEEEYEQDERDQKEEGNDYDTR 267
Score = 37.4 bits (85), Expect = 0.043
Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 11/89 (12%)
Query: 342 SDNLGEQPTKCSPEEDEEDEEDVDDE----DHDEGF-GSEHELSENEEEEEE--EEDYED 394
S+ +G + + + + +E+V+ E DH+ G GS E N E EEE EED E+
Sbjct: 152 SERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEE 211
Query: 395 D----KDDDISDTFSEPGYENDSVEDLKE 419
D +D + + E G E + E+ +E
Sbjct: 212 DEEVEEDAEEDEEVDEDGEEEEEEEEEEE 240
Score = 37.0 bits (84), Expect = 0.056
Identities = 23/87 (26%), Positives = 45/87 (51%), Gaps = 7/87 (8%)
Query: 347 EQPTKCSPEEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSE 406
E+ + EE+EE+EE+ ++E+ +E E E +E +++EE + D + SD+ SE
Sbjct: 223 EEVDEDGEEEEEEEEEEEEEEEEEE------EEYEQDERDQKEEGNDYDTRSEASDSGSE 276
Query: 407 P-GYENDSVEDLKEVTSISSRKRGKRR 432
+ + SV +K+ ++R
Sbjct: 277 SVSFTDGSVRSGSGTDGSDEKKKERKR 303
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 49.3 bits (116), Expect = 1e-05
Identities = 24/46 (52%), Positives = 30/46 (65%)
Query: 348 QPTKCSPEEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYE 393
QP EE+EE+EED ++E+ DE E E E EEEEEEEE+ E
Sbjct: 726 QPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 40.4 bits (93), Expect = 0.005
Identities = 20/45 (44%), Positives = 30/45 (66%), Gaps = 4/45 (8%)
Query: 346 GEQPTKCSPEEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEE 390
G++ + E++EE+EED ++E+ +E E E E EEEEEEEE
Sbjct: 731 GKEEEEEEEEDEEEEEEDEEEEEEEE----EEEEEEEEEEEEEEE 771
Score = 35.0 bits (79), Expect = 0.21
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 374 GSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKEVTSISSRKRGKRRY 433
G E E E E+EEEEEED E++++++ + E E + E+ ++ +
Sbjct: 731 GKEEEEEEEEDEEEEEEDEEEEEEEEEEE--EEEEEEEEEEEEAAAAVALGEVLGPRSGS 788
Query: 434 FWEYSEQLTPSQQE 447
E SE+ T QE
Sbjct: 789 SSEGSERSTDRSQE 802
Score = 30.0 bits (66), Expect = 6.8
Identities = 13/40 (32%), Positives = 25/40 (62%)
Query: 380 SENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKE 419
+ +EEEEEEE+ E+++++D + E E + E+ +E
Sbjct: 729 ANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEE 768
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 48.5 bits (114), Expect = 2e-05
Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 18/77 (23%)
Query: 355 EEDEEDEEDVDDEDHDE------------------GFGSEHELSENEEEEEEEEDYEDDK 396
E +E+DEED DDED DE SE E + +E EE++ED +DD+
Sbjct: 639 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDE 698
Query: 397 DDDISDTFSEPGYENDS 413
DDD + G + S
Sbjct: 699 DDDEDEDNESEGSSSSS 715
Score = 40.0 bits (92), Expect = 0.007
Identities = 27/121 (22%), Positives = 56/121 (46%), Gaps = 12/121 (9%)
Query: 293 KETQELLLSPLPQEGPGSLAAGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKC 352
+++ L P P+ +L + S D + +EE + S G ++
Sbjct: 616 RKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSES 675
Query: 353 SPEEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYEND 412
S E++ ED ++ +++D DE +++E+++ED ED++ + S + S G +D
Sbjct: 676 SSEDESEDGDENEEDDEDE-----------DDDEDDDED-EDNESEGSSSSSSSSGDSSD 723
Query: 413 S 413
S
Sbjct: 724 S 724
Score = 33.5 bits (75), Expect = 0.62
Identities = 16/53 (30%), Positives = 27/53 (50%)
Query: 342 SDNLGEQPTKCSPEEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYED 394
S++ E ++ E +E+DE++ DDED DE +E E S + + D
Sbjct: 673 SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSD 725
Score = 33.1 bits (74), Expect = 0.81
Identities = 19/87 (21%), Positives = 37/87 (42%), Gaps = 20/87 (22%)
Query: 305 QEGPGSLAAGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDEEDV 364
+ G S G+SS S+ D + +E+ +EDE+D+ED
Sbjct: 661 ENGDSSEDGGDSSESSSEDESEDGDENEED--------------------DEDEDDDEDD 700
Query: 365 DDEDHDEGFGSEHELSENEEEEEEEED 391
D+++ +E GS S + + + + +
Sbjct: 701 DEDEDNESEGSSSSSSSSGDSSDSDSN 727
Score = 32.7 bits (73), Expect = 1.1
Identities = 18/50 (36%), Positives = 29/50 (58%), Gaps = 1/50 (2%)
Query: 380 SENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKEVTSISSRKRG 429
S++E EE++EED EDD+D+D + E G ++ D E +S + G
Sbjct: 636 SKSESEEDDEED-EDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDG 684
Score = 31.6 bits (70), Expect = 2.3
Identities = 17/59 (28%), Positives = 28/59 (47%), Gaps = 1/59 (1%)
Query: 358 EEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVED 416
+ E +D++ DE E E E++E + ED D + D SE G EN+ ++
Sbjct: 635 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDE-SEDGDENEEDDE 692
Score = 31.2 bits (69), Expect = 3.1
Identities = 16/43 (37%), Positives = 23/43 (53%)
Query: 383 EEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKEVTSISS 425
+ + E EED E+D+DD+ D E DS ED + + SS
Sbjct: 635 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSS 677
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 48.5 bits (114), Expect = 2e-05
Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 18/77 (23%)
Query: 355 EEDEEDEEDVDDEDHDE------------------GFGSEHELSENEEEEEEEEDYEDDK 396
E +E+DEED DDED DE SE E + +E EE++ED +DD+
Sbjct: 639 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDE 698
Query: 397 DDDISDTFSEPGYENDS 413
DDD + G + S
Sbjct: 699 DDDEDEDNESEGSSSSS 715
Score = 40.0 bits (92), Expect = 0.007
Identities = 27/121 (22%), Positives = 56/121 (46%), Gaps = 12/121 (9%)
Query: 293 KETQELLLSPLPQEGPGSLAAGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKC 352
+++ L P P+ +L + S D + +EE + S G ++
Sbjct: 616 RKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSES 675
Query: 353 SPEEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYEND 412
S E++ ED ++ +++D DE +++E+++ED ED++ + S + S G +D
Sbjct: 676 SSEDESEDGDENEEDDEDE-----------DDDEDDDED-EDNESEGSSSSSSSSGDSSD 723
Query: 413 S 413
S
Sbjct: 724 S 724
Score = 33.5 bits (75), Expect = 0.62
Identities = 16/53 (30%), Positives = 27/53 (50%)
Query: 342 SDNLGEQPTKCSPEEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYED 394
S++ E ++ E +E+DE++ DDED DE +E E S + + D
Sbjct: 673 SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSD 725
Score = 33.1 bits (74), Expect = 0.81
Identities = 19/87 (21%), Positives = 37/87 (42%), Gaps = 20/87 (22%)
Query: 305 QEGPGSLAAGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDEEDV 364
+ G S G+SS S+ D + +E+ +EDE+D+ED
Sbjct: 661 ENGDSSEDGGDSSESSSEDESEDGDENEED--------------------DEDEDDDEDD 700
Query: 365 DDEDHDEGFGSEHELSENEEEEEEEED 391
D+++ +E GS S + + + + +
Sbjct: 701 DEDEDNESEGSSSSSSSSGDSSDSDSN 727
Score = 32.7 bits (73), Expect = 1.1
Identities = 18/50 (36%), Positives = 29/50 (58%), Gaps = 1/50 (2%)
Query: 380 SENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKEVTSISSRKRG 429
S++E EE++EED EDD+D+D + E G ++ D E +S + G
Sbjct: 636 SKSESEEDDEED-EDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDG 684
Score = 31.6 bits (70), Expect = 2.3
Identities = 17/59 (28%), Positives = 28/59 (47%), Gaps = 1/59 (1%)
Query: 358 EEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVED 416
+ E +D++ DE E E E++E + ED D + D SE G EN+ ++
Sbjct: 635 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDE-SEDGDENEEDDE 692
Score = 31.2 bits (69), Expect = 3.1
Identities = 16/43 (37%), Positives = 23/43 (53%)
Query: 383 EEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKEVTSISS 425
+ + E EED E+D+DD+ D E DS ED + + SS
Sbjct: 635 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSS 677
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 48.5 bits (114), Expect = 2e-05
Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 18/77 (23%)
Query: 355 EEDEEDEEDVDDEDHDE------------------GFGSEHELSENEEEEEEEEDYEDDK 396
E +E+DEED DDED DE SE E + +E EE++ED +DD+
Sbjct: 676 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDE 735
Query: 397 DDDISDTFSEPGYENDS 413
DDD + G + S
Sbjct: 736 DDDEDEDNESEGSSSSS 752
Score = 40.0 bits (92), Expect = 0.007
Identities = 27/121 (22%), Positives = 56/121 (46%), Gaps = 12/121 (9%)
Query: 293 KETQELLLSPLPQEGPGSLAAGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKC 352
+++ L P P+ +L + S D + +EE + S G ++
Sbjct: 653 RKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSES 712
Query: 353 SPEEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYEND 412
S E++ ED ++ +++D DE +++E+++ED ED++ + S + S G +D
Sbjct: 713 SSEDESEDGDENEEDDEDE-----------DDDEDDDED-EDNESEGSSSSSSSSGDSSD 760
Query: 413 S 413
S
Sbjct: 761 S 761
Score = 33.5 bits (75), Expect = 0.62
Identities = 16/53 (30%), Positives = 27/53 (50%)
Query: 342 SDNLGEQPTKCSPEEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYED 394
S++ E ++ E +E+DE++ DDED DE +E E S + + D
Sbjct: 710 SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSD 762
Score = 33.1 bits (74), Expect = 0.81
Identities = 19/87 (21%), Positives = 37/87 (42%), Gaps = 20/87 (22%)
Query: 305 QEGPGSLAAGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDEEDV 364
+ G S G+SS S+ D + +E+ +EDE+D+ED
Sbjct: 698 ENGDSSEDGGDSSESSSEDESEDGDENEED--------------------DEDEDDDEDD 737
Query: 365 DDEDHDEGFGSEHELSENEEEEEEEED 391
D+++ +E GS S + + + + +
Sbjct: 738 DEDEDNESEGSSSSSSSSGDSSDSDSN 764
Score = 32.7 bits (73), Expect = 1.1
Identities = 18/50 (36%), Positives = 29/50 (58%), Gaps = 1/50 (2%)
Query: 380 SENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKEVTSISSRKRG 429
S++E EE++EED EDD+D+D + E G ++ D E +S + G
Sbjct: 673 SKSESEEDDEED-EDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDG 721
Score = 31.6 bits (70), Expect = 2.3
Identities = 17/59 (28%), Positives = 28/59 (47%), Gaps = 1/59 (1%)
Query: 358 EEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVED 416
+ E +D++ DE E E E++E + ED D + D SE G EN+ ++
Sbjct: 672 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDE-SEDGDENEEDDE 729
Score = 31.2 bits (69), Expect = 3.1
Identities = 16/43 (37%), Positives = 23/43 (53%)
Query: 383 EEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKEVTSISS 425
+ + E EED E+D+DD+ D E DS ED + + SS
Sbjct: 672 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSS 714
>gi|4505999 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 48.1 bits (113), Expect = 2e-05
Identities = 44/154 (28%), Positives = 68/154 (44%), Gaps = 32/154 (20%)
Query: 275 EKKGMEPLQGHATPALPFKETQELLLSPLPQEGPGSLAAGESSSLS-------------- 320
E+ G + L G A P +ET P + GP + A SS S
Sbjct: 179 EEPGSQGLNGEAGPEDSTRET------PSQENGPTAKAYTGFSSNSERGTEAGQVGEPGI 232
Query: 321 ----ASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDEEDVDDEDHDEGFGSE 376
A S S +S K S F D+ E S E +EE+E+ + + ++G+ SE
Sbjct: 233 PTGEAGPSCSSASDKLPRVAKSKFFEDSEDE-----SDEAEEEEEDSEECSEEEDGYSSE 287
Query: 377 HELSENEEEEEEEEDYEDDKDDDISDTFSEPGYE 410
+ENEE+E++ E+ E+D D++ + PG E
Sbjct: 288 E--AENEEDEDDTEEAEED-DEEEEEEMMVPGME 318
Score = 36.2 bits (82), Expect = 0.095
Identities = 26/102 (25%), Positives = 46/102 (45%), Gaps = 7/102 (6%)
Query: 302 PLPQEGPGSLAAGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDE 361
P + GP +A + A + + S+ + + ++ E +CS EED
Sbjct: 233 PTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDE------AEEEEEDSEECSEEEDGYSS 286
Query: 362 EDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDT 403
E+ ++E+ DE E E + EEEEE + K++ SD+
Sbjct: 287 EEAENEE-DEDDTEEAEEDDEEEEEEMMVPGMEGKEEPGSDS 327
>gi|29826282 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 48.1 bits (113), Expect = 2e-05
Identities = 44/154 (28%), Positives = 68/154 (44%), Gaps = 32/154 (20%)
Query: 275 EKKGMEPLQGHATPALPFKETQELLLSPLPQEGPGSLAAGESSSLS-------------- 320
E+ G + L G A P +ET P + GP + A SS S
Sbjct: 179 EEPGSQGLNGEAGPEDSTRET------PSQENGPTAKAYTGFSSNSERGTEAGQVGEPGI 232
Query: 321 ----ASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDEEDVDDEDHDEGFGSE 376
A S S +S K S F D+ E S E +EE+E+ + + ++G+ SE
Sbjct: 233 PTGEAGPSCSSASDKLPRVAKSKFFEDSEDE-----SDEAEEEEEDSEECSEEEDGYSSE 287
Query: 377 HELSENEEEEEEEEDYEDDKDDDISDTFSEPGYE 410
+ENEE+E++ E+ E+D D++ + PG E
Sbjct: 288 E--AENEEDEDDTEEAEED-DEEEEEEMMVPGME 318
Score = 36.2 bits (82), Expect = 0.095
Identities = 26/102 (25%), Positives = 46/102 (45%), Gaps = 7/102 (6%)
Query: 302 PLPQEGPGSLAAGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDE 361
P + GP +A + A + + S+ + + ++ E +CS EED
Sbjct: 233 PTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDE------AEEEEEDSEECSEEEDGYSS 286
Query: 362 EDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDT 403
E+ ++E+ DE E E + EEEEE + K++ SD+
Sbjct: 287 EEAENEE-DEDDTEEAEEDDEEEEEEMMVPGMEGKEEPGSDS 327
>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
sapiens]
Length = 631
Score = 47.8 bits (112), Expect = 3e-05
Identities = 37/130 (28%), Positives = 59/130 (45%), Gaps = 5/130 (3%)
Query: 308 PGSLAAGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEEDEEDVDDE 367
P + SS S S + E+ + L ++L P E+E + E+ D+E
Sbjct: 63 PNDASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLV---GEEETEREEEDEE 119
Query: 368 DHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKEVTS-ISSR 426
+EG G E E E EEEEEEEE+ E+++ S +E S+E+ + + +SS
Sbjct: 120 IQEEG-GEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEEWVSSE 178
Query: 427 KRGKRRYFWE 436
R W+
Sbjct: 179 TSALPRPRWQ 188
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.127 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,824,761
Number of Sequences: 37866
Number of extensions: 1370977
Number of successful extensions: 25936
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 512
Number of HSP's successfully gapped in prelim test: 445
Number of HSP's that attempted gapping in prelim test: 9408
Number of HSP's gapped (non-prelim): 6507
length of query: 639
length of database: 18,247,518
effective HSP length: 109
effective length of query: 530
effective length of database: 14,120,124
effective search space: 7483665720
effective search space used: 7483665720
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.