Search of human proteins with 237757328

Search of human proteins with 237757328

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|237757328 oligodendrocyte transcription factor 1 [Homo
sapiens]
         (271 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|237757328 oligodendrocyte transcription factor 1 [Homo sapiens]    536   e-153
gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo...   109   2e-24
gi|28411948 oligodendrocyte transcription factor 3 [Homo sapiens]      98   7e-21
gi|22748877 basic helix-loop-helix domain containing, class B, 5...    88   7e-18
gi|57529222 basic helix-loop-helix domain containing, class B, 4...    84   1e-16
gi|29126247 basic helix-loop-helix family, member a15 [Homo sapi...    65   6e-11
gi|48255909 basic helix-loop-helix transcription factor 15 [Homo...    61   1e-09
gi|98986461 neurogenic differentiation 2 [Homo sapiens]                60   2e-09
gi|148922889 scleraxis homolog B [Homo sapiens]                        57   2e-08
gi|186972126 scleraxis homolog A [Homo sapiens]                        57   2e-08
gi|68989258 neurogenin 3 [Homo sapiens]                                57   2e-08
gi|31077092 neurogenin 2 [Homo sapiens]                                55   8e-08
gi|4507741 twist [Homo sapiens]                                        54   1e-07
gi|153792190 neurogenic differentiation 4 [Homo sapiens]               54   2e-07
gi|38455396 neurogenin 1 [Homo sapiens]                                53   3e-07
gi|121114306 neurogenic differentiation 1 [Homo sapiens]               52   4e-07
gi|30039710 pancreas specific transcription factor, 1a [Homo sap...    52   7e-07
gi|17981708 twist homolog 2 [Homo sapiens]                             51   9e-07
gi|226498192 atonal homolog 8 [Homo sapiens]                           51   1e-06
gi|239751178 PREDICTED: basic helix-loop-helix family, member a9...    51   1e-06
gi|239745666 PREDICTED: basic helix-loop-helix family, member a9...    51   1e-06
gi|21553337 atonal homolog 7 [Homo sapiens]                            50   2e-06
gi|27475985 neurogenic differentiation 6 [Homo sapiens]                49   4e-06
gi|14149724 mesoderm posterior 1 [Homo sapiens]                        48   1e-05
gi|116805332 musculin [Homo sapiens]                                   47   1e-05
gi|34147558 lymphoblastic leukemia derived sequence 1 [Homo sapi...    47   2e-05
gi|4885075 atonal homolog 1 [Homo sapiens]                             45   9e-05
gi|239756681 PREDICTED: basic helix-loop-helix family, member a9...    44   1e-04
gi|239749439 PREDICTED: similar to transcription factor 23 [Homo...    44   1e-04
gi|239743573 PREDICTED: similar to transcription factor 23 [Homo...    44   1e-04

>gi|237757328 oligodendrocyte transcription factor 1 [Homo sapiens]
          Length = 271

 Score =  536 bits (1382), Expect = e-153
 Identities = 271/271 (100%), Positives = 271/271 (100%)

Query: 1   MYYAVSQARVNAVPGTMLRPQRPGDLQLGASLYELVGYRQPPSSSSSSTSSTSSTSSSST 60
           MYYAVSQARVNAVPGTMLRPQRPGDLQLGASLYELVGYRQPPSSSSSSTSSTSSTSSSST
Sbjct: 1   MYYAVSQARVNAVPGTMLRPQRPGDLQLGASLYELVGYRQPPSSSSSSTSSTSSTSSSST 60

Query: 61  TAPLLPKAAREKPEAPAEPPGPGPGSGAHPGGSARPDAKEEQQQQLRRKINSRERKRMQD 120
           TAPLLPKAAREKPEAPAEPPGPGPGSGAHPGGSARPDAKEEQQQQLRRKINSRERKRMQD
Sbjct: 61  TAPLLPKAAREKPEAPAEPPGPGPGSGAHPGGSARPDAKEEQQQQLRRKINSRERKRMQD 120

Query: 121 LNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQELRRALGEGAG 180
           LNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQELRRALGEGAG
Sbjct: 121 LNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQELRRALGEGAG 180

Query: 181 PAAPRLLLAGLPLLAAAPGSVLLAPGAVGPPDALRPAKYLSLALDEPPCGQFALPGGGAG 240
           PAAPRLLLAGLPLLAAAPGSVLLAPGAVGPPDALRPAKYLSLALDEPPCGQFALPGGGAG
Sbjct: 181 PAAPRLLLAGLPLLAAAPGSVLLAPGAVGPPDALRPAKYLSLALDEPPCGQFALPGGGAG 240

Query: 241 GPGLCTCAVCKFPHLVPASLGLAAVQAQFSK 271
           GPGLCTCAVCKFPHLVPASLGLAAVQAQFSK
Sbjct: 241 GPGLCTCAVCKFPHLVPASLGLAAVQAQFSK 271


>gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo
           sapiens]
          Length = 323

 Score =  109 bits (273), Expect = 2e-24
 Identities = 102/297 (34%), Positives = 124/297 (41%), Gaps = 107/297 (36%)

Query: 43  SSSSSSTSSTSSTSSSSTTAPLLPKAAREKPEAPAEPPGPGPGSGAHPG----------- 91
           S  SS ++ T  T SSST +          PE  AE  G    +GAHPG           
Sbjct: 26  SKGSSGSAFTGGTVSSSTPSDC-------PPELSAELRGAMGSAGAHPGDKLGGSGFKSS 78

Query: 92  -------------GSARPDAK---EEQQQQLRRKINSRERKRMQDLNLAMDALREVILPY 135
                         S + D K   E + QQLR KINSRERKRM DLN+AMD LREV +PY
Sbjct: 79  SSSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSRERKRMHDLNIAMDGLREV-MPY 137

Query: 136 SAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQELRRALGE-------GAGPAAPRLLL 188
           +     G   RKLSKIATLLLARNYIL+L +SL+E++R + E       G  P+A   L 
Sbjct: 138 A----HGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYGGHHAGFHPSACGGLA 193

Query: 189 AGLPLLAAA-----------------------------------------PGSVLLAPGA 207
              PL AA                                          PGS L + G+
Sbjct: 194 HSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSSASLPGSGLPSVGS 253

Query: 208 VGPPDALRPAKYLSLALDEPPCGQFALPGGGAGGPGL-----------CTCAVCKFP 253
           + PP  L         L  P     A  GGG GG G            C C++C+ P
Sbjct: 254 IRPPHGL---------LKSPSAAAAAPLGGGGGGSGASGGFQHWGGMPCPCSMCQVP 301


>gi|28411948 oligodendrocyte transcription factor 3 [Homo sapiens]
          Length = 272

 Score = 98.2 bits (243), Expect = 7e-21
 Identities = 79/177 (44%), Positives = 91/177 (51%), Gaps = 30/177 (16%)

Query: 100 EEQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARN 159
           E+  QQLR KIN RERKRM DLNLAMD LREV +PY+     G   RKLSKIATLLLARN
Sbjct: 78  EQDLQQLRLKINGRERKRMHDLNLAMDGLREV-MPYA----HGPSVRKLSKIATLLLARN 132

Query: 160 YILLLGSSLQELRRALGEGAGPAAPRLLL------AGLPLLAAAP--------GSVLLAP 205
           YIL+L SSL+E++R +GE  G              AG P  AA          G  L + 
Sbjct: 133 YILMLTSSLEEMKRLVGEIYGGHHSAFHCGTVGHSAGHPAHAANSVHPVHPILGGALSSG 192

Query: 206 GAVGPPDA--------LRPAKYLSLALDEPPCGQFALPGGGAGGPGL-CTCAVCKFP 253
            A  P  A        +RP   L  A   PP  Q  L  G     GL C C +C+ P
Sbjct: 193 NASSPLSAASLPAIGTIRPPHSLLKAPSTPPALQ--LGSGFQHWAGLPCPCTICQMP 247


>gi|22748877 basic helix-loop-helix domain containing, class B, 5
           [Homo sapiens]
          Length = 381

 Score = 88.2 bits (217), Expect = 7e-18
 Identities = 61/132 (46%), Positives = 77/132 (58%), Gaps = 13/132 (9%)

Query: 81  GPGPGSGAHPGGSARPDAKEEQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHC 140
           G G GSG     S+    K ++Q+ LR  IN+RER+RM DLN A+D LR VI PY  AH 
Sbjct: 218 GSGSGSGGSSSSSSSSSKKSKEQKALRLNINARERRRMHDLNDALDELRAVI-PY--AHS 274

Query: 141 QGAPGRKLSKIATLLLARNYILLLGSSLQELRRA---LGEGAGPAAPRLLLAGLPLLAAA 197
                RKLSKIATLLLA+NYIL+   +L+E+RR    L +G   +A     A LP  AAA
Sbjct: 275 PSV--RKLSKIATLLLAKNYILMQAQALEEMRRLVAYLNQGQAISA-----ASLPSSAAA 327

Query: 198 PGSVLLAPGAVG 209
             +      A+G
Sbjct: 328 AAAAAALHPALG 339


>gi|57529222 basic helix-loop-helix domain containing, class B, 4
           [Homo sapiens]
          Length = 225

 Score = 84.3 bits (207), Expect = 1e-16
 Identities = 71/163 (43%), Positives = 86/163 (52%), Gaps = 28/163 (17%)

Query: 66  PKAAREKPEAPAEPPGP------------GPGSGAHPGGSARPDAKEEQQQQLRRKINSR 113
           P+A  +  E+  E  G             GPGS A   G  RP     +Q+ LR  IN+R
Sbjct: 55  PRAPAQAAESSGEQSGDEDDAFEQRRRRRGPGSAAD--GRRRP----REQRSLRLSINAR 108

Query: 114 ERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQELRR 173
           ER+RM DLN A+D LR VI PY  AH      RKLSKIATLLLA+NYIL+   +L E+RR
Sbjct: 109 ERRRMHDLNDALDGLRAVI-PY--AHSPSV--RKLSKIATLLLAKNYILMQAQALDEMRR 163

Query: 174 A---LGEGAGPAAPRLLLAGLPLLAAAPGSVLLAPGAVGP-PD 212
               L +G G AAP +  A L     A      A  A+GP PD
Sbjct: 164 LVAFLNQGQGLAAP-VNAAPLTPFGQATVCPFSAGAALGPCPD 205


>gi|29126247 basic helix-loop-helix family, member a15 [Homo
           sapiens]
          Length = 189

 Score = 65.1 bits (157), Expect = 6e-11
 Identities = 51/148 (34%), Positives = 69/148 (46%), Gaps = 9/148 (6%)

Query: 39  RQPPSSSSSSTSSTSSTSSSSTTAPLLPKAAREKPEAPAEPPGPGPGSGAHPGGSARPDA 98
           R P   + ++    +   S     P   K  R +P A A    PG G    PG S  P  
Sbjct: 11  RAPVQDTEATPGEGTPDGSLPNPGPEPAKGLRSRP-ARAAARAPGEGRRRRPGPSG-PGG 68

Query: 99  KEEQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLAR 158
           + +   Q R + N RER+RM  LN A  ALREVI P+  A       +KLSKI TL LA+
Sbjct: 69  RRDSSIQRRLESNERERQRMHKLNNAFQALREVI-PHVRA------DKKLSKIETLTLAK 121

Query: 159 NYILLLGSSLQELRRALGEGAGPAAPRL 186
           NYI  L +++  +  +   G     P+L
Sbjct: 122 NYIKSLTATILTMSSSRLPGLEGPGPKL 149


>gi|48255909 basic helix-loop-helix transcription factor 15 [Homo
           sapiens]
          Length = 199

 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 54/124 (43%), Positives = 60/124 (48%), Gaps = 22/124 (17%)

Query: 71  EKPEAPAEPPGPGPGSGAHPGGSARPDAKEEQQQQLRRKINSRERKRMQDLNLAMDALRE 130
           E PEA    PGPG G  A  GG A P     Q    R+  N+RER R Q +N A  ALR 
Sbjct: 42  EGPEAARRGPGPGGGRRAGGGGGAGPVVVVRQ----RQAANARERDRTQSVNTAFTALRT 97

Query: 131 VILPYSAAHCQGAPGRKLSKIATLLLARNYI------LLLGSSL---QELRRALG--EGA 179
           +I             RKLSKI TL LA +YI      LLLG S    Q   RA G  +GA
Sbjct: 98  LIPTEPV-------DRKLSKIETLRLASSYIAHLANVLLLGDSADDGQPCFRAAGSAKGA 150

Query: 180 GPAA 183
            PAA
Sbjct: 151 VPAA 154


>gi|98986461 neurogenic differentiation 2 [Homo sapiens]
          Length = 382

 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 62/187 (33%), Positives = 80/187 (42%), Gaps = 25/187 (13%)

Query: 71  EKPEAPAEPPGPGPGSGAHP---GGSARP--DAKEEQQQQLRRKINSRERKRMQDLNLAM 125
           E+ E   E  G     G  P   G   R    A+ E+ +  R+K N+RER RM DLN A+
Sbjct: 82  EEEEEEEEEEGLDEAEGERPKKRGPKKRKMTKARLERSKLRRQKANARERNRMHDLNAAL 141

Query: 126 DALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQELRR--------ALGE 177
           D LR+V+  YS         +KLSKI TL LA+NYI  L   L+  +R         L +
Sbjct: 142 DNLRKVVPCYSKT-------QKLSKIETLRLAKNYIWALSEILRSGKRPDLVSYVQTLCK 194

Query: 178 GAGPAAPRLLLAGLPLLAAAPGSVLLAPGA-----VGPPDALRPAKYLSLALDEPPCGQF 232
           G       L+   L L +    +   A GA      G P A+ P  Y    L    C   
Sbjct: 195 GLSQPTTNLVAGCLQLNSRNFLTEQGADGAGRFHGSGGPFAMHPYPYPCSRLAGAQCQAA 254

Query: 233 ALPGGGA 239
              GGGA
Sbjct: 255 GGLGGGA 261


>gi|148922889 scleraxis homolog B [Homo sapiens]
          Length = 201

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 62/179 (34%), Positives = 71/179 (39%), Gaps = 30/179 (16%)

Query: 18  LRPQRPGDLQLGASLYELVGYRQPPSSSSSSTSSTSSTSSSSTTAPLLPKAAREKPEAPA 77
           LRP  PG             Y  P  S  S      S SS S   P    AAR   +   
Sbjct: 6   LRPAPPGR------------YLYPEVSPLSEDEDRGSDSSGSDEKPCRVHAARCGLQGAR 53

Query: 78  EPPGPGPGSGAHPGGSARPDAKEEQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSA 137
              G     G  PGG  RP  +  Q    R   N+RER R   +N A  ALR +I    A
Sbjct: 54  RRAGGRRAGGGGPGG--RPGREPRQ----RHTANARERDRTNSVNTAFTALRTLIPTEPA 107

Query: 138 AHCQGAPGRKLSKIATLLLARNYILLLGSSLQELRRALGEG----AGPAAPRLLLAGLP 192
                   RKLSKI TL LA +YI  LG+ L     A G+G    +GPA      AG P
Sbjct: 108 -------DRKLSKIETLRLASSYISHLGNVLL-AGEACGDGQPCHSGPAFFHAARAGSP 158


>gi|186972126 scleraxis homolog A [Homo sapiens]
          Length = 201

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 62/179 (34%), Positives = 71/179 (39%), Gaps = 30/179 (16%)

Query: 18  LRPQRPGDLQLGASLYELVGYRQPPSSSSSSTSSTSSTSSSSTTAPLLPKAAREKPEAPA 77
           LRP  PG             Y  P  S  S      S SS S   P    AAR   +   
Sbjct: 6   LRPAPPGR------------YLYPEVSPLSEDEDRGSDSSGSDEKPCRVHAARCGLQGAR 53

Query: 78  EPPGPGPGSGAHPGGSARPDAKEEQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSA 137
              G     G  PGG  RP  +  Q    R   N+RER R   +N A  ALR +I    A
Sbjct: 54  RRAGGRRAGGGGPGG--RPGREPRQ----RHTANARERDRTNSVNTAFTALRTLIPTEPA 107

Query: 138 AHCQGAPGRKLSKIATLLLARNYILLLGSSLQELRRALGEG----AGPAAPRLLLAGLP 192
                   RKLSKI TL LA +YI  LG+ L     A G+G    +GPA      AG P
Sbjct: 108 -------DRKLSKIETLRLASSYISHLGNVLL-AGEACGDGQPCHSGPAFFHAARAGSP 158


>gi|68989258 neurogenin 3 [Homo sapiens]
          Length = 214

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 59/202 (29%), Positives = 82/202 (40%), Gaps = 38/202 (18%)

Query: 41  PPSSSSSSTSSTSSTSSSSTTAPLLPKAAREKPEAPAE-PPGPGPGSG------------ 87
           P  S + +   T  T  S       P+A+ ++   P   PP P    G            
Sbjct: 3   PQPSGAPTVQVTRETERS------FPRASEDEVTCPTSAPPSPTRTRGNCAEAEEGGCRG 56

Query: 88  ------AHPGGSARPDAK---EEQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAA 138
                 A  GG +RP ++    +Q++  R+K N RER RM +LN A+DALR V+  +   
Sbjct: 57  APRKLRARRGGRSRPKSELALSKQRRSRRKKANDRERNRMHNLNSALDALRGVLPTF--- 113

Query: 139 HCQGAPGRKLSKIATLLLARNYILLLGSSLQELRRALGEGAGPAAPRLLLAGLPLLAAAP 198
                   KL+KI TL  A NYI  L  +L+    +L     P AP     G P    +P
Sbjct: 114 ----PDDAKLTKIETLRFAHNYIWALTQTLRIADHSL-YALEPPAPHCGELGSP--GGSP 166

Query: 199 GSVLLAPGAVGPPDALRPAKYL 220
           G        V    +L PA  L
Sbjct: 167 GDWGSLYSPVSQAGSLSPAASL 188


>gi|31077092 neurogenin 2 [Homo sapiens]
          Length = 272

 Score = 54.7 bits (130), Expect = 8e-08
 Identities = 41/122 (33%), Positives = 57/122 (46%), Gaps = 9/122 (7%)

Query: 92  GSARPDAKEEQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKI 151
           G+   +  +  ++  R K N+RER RM +LN A+DALREV+  +           KL+KI
Sbjct: 99  GAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTF-------PEDAKLTKI 151

Query: 152 ATLLLARNYILLLGSSLQELRRALGEGAGPAAPRLLLAGLPLLAAAPGSVLLAPGAVGPP 211
            TL  A NYI  L  +L+      G G G   P  L +   LL+    S  L+     P 
Sbjct: 152 ETLRFAHNYIWALTETLRLADHCGGGGGG--LPGALFSEAVLLSPGGASAALSSSGDSPS 209

Query: 212 DA 213
            A
Sbjct: 210 PA 211


>gi|4507741 twist [Homo sapiens]
          Length = 202

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 60/168 (35%), Positives = 71/168 (42%), Gaps = 30/168 (17%)

Query: 20  PQRPGDLQLGASLYELVGYRQPPSSSSSSTSSTSSTSSSSTTAPLLPKAAR-------EK 72
           P  P D  L  S  E    +QPPS         SS  S+   A   P  A        ++
Sbjct: 9   PVSPADDSLSNSEEE-PDRQQPPSGKRGGRKRRSSRRSAGGGAG--PGGAAGGGVGGGDE 65

Query: 73  PEAPAE------PPGPGPGSGAHPGGSAR-----PDAKEEQQQQLRRKINSRERKRMQDL 121
           P +PA+        G G G GA  GG +      P + EE Q Q R   N RER+R Q L
Sbjct: 66  PGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQ-RVMANVRERQRTQSL 124

Query: 122 NLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQ 169
           N A  ALR++I           P  KLSKI TL LA  YI  L   LQ
Sbjct: 125 NEAFAALRKII--------PTLPSDKLSKIQTLKLAARYIDFLYQVLQ 164


>gi|153792190 neurogenic differentiation 4 [Homo sapiens]
          Length = 331

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 54/145 (37%), Positives = 68/145 (46%), Gaps = 21/145 (14%)

Query: 98  AKEEQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLA 157
           A+ E+ +  R K N+RER RM  LN A+D LR V+  YS         +KLSKI TL LA
Sbjct: 80  ARLERFRARRVKANARERTRMHGLNDALDNLRRVMPCYSKT-------QKLSKIETLRLA 132

Query: 158 RNYILLLGSSLQELRRALGEG------AGPAAPRL-LLAGLPLLAAAPGSVLLAPGAVGP 210
           RNYI  L   L+  +   G+G       G + P   L+AG   L   P SVLL       
Sbjct: 133 RNYIWALSEVLETGQTPEGKGFVEMLCKGLSQPTSNLVAG--CLQLGPQSVLLEKHEDKS 190

Query: 211 P-----DALRPAKYLSLALDEPPCG 230
           P      ++    Y S  L  PP G
Sbjct: 191 PICDSAISVHNFNYQSPGLPSPPYG 215


>gi|38455396 neurogenin 1 [Homo sapiens]
          Length = 237

 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 51/161 (31%), Positives = 71/161 (44%), Gaps = 27/161 (16%)

Query: 44  SSSSSTSSTSSTSSSSTTAPLLPKAAREKPEAPAEPPGPGPGSGAHPGGSARPDAKEEQQ 103
           +SSS +  +   +     A L   A+   P APA    P     +   G A+ D +E ++
Sbjct: 15  ASSSGSDLSGFLTDEEDCARLQQAASASGPPAPARRGAPNISRASEVPG-AQDDEQERRR 73

Query: 104 QQ-------------LRR----KINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGR 146
           ++             LRR    K N RER RM +LN A+DALR V+  +           
Sbjct: 74  RRGRTRVRSEALLHSLRRSRRVKANDRERNRMHNLNAALDALRSVLPSF-------PDDT 126

Query: 147 KLSKIATLLLARNYILLLGSSLQELRRALGEGAGPAAPRLL 187
           KL+KI TL  A NYI  L  +L+   + L    G A  RLL
Sbjct: 127 KLTKIETLRFAYNYIWALAETLRLADQGL--PGGGARERLL 165


>gi|121114306 neurogenic differentiation 1 [Homo sapiens]
          Length = 356

 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 33/72 (45%), Positives = 43/72 (59%), Gaps = 7/72 (9%)

Query: 98  AKEEQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLA 157
           A+ E+ +  R K N+RER RM  LN A+D LR+V+  YS         +KLSKI TL LA
Sbjct: 94  ARLERFKLRRMKANARERNRMHGLNAALDNLRKVVPCYSKT-------QKLSKIETLRLA 146

Query: 158 RNYILLLGSSLQ 169
           +NYI  L   L+
Sbjct: 147 KNYIWALSEILR 158


>gi|30039710 pancreas specific transcription factor, 1a [Homo
           sapiens]
          Length = 328

 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 45/127 (35%), Positives = 57/127 (44%), Gaps = 17/127 (13%)

Query: 62  APLLPKAAREKPEAPAEPPGPGP------GSGAHPGGSARPDAKEEQQQQLRRKINSRER 115
           +P  P +    P A A    PG       G+ A      R    E + QQLR+  N RER
Sbjct: 114 SPGSPPSCLAYPCAGAAVLSPGARLRGLSGAAAAAARRRRRVRSEAELQQLRQAANVRER 173

Query: 116 KRMQDLNLAMDALREVI--LPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQELRR 173
           +RMQ +N A + LR  I  LPY          ++LSK+ TL LA  YI  L   +Q    
Sbjct: 174 RRMQSINDAFEGLRSHIPTLPYE---------KRLSKVDTLRLAIGYINFLSELVQADLP 224

Query: 174 ALGEGAG 180
             G GAG
Sbjct: 225 LRGGGAG 231


>gi|17981708 twist homolog 2 [Homo sapiens]
          Length = 160

 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 45/128 (35%), Positives = 55/128 (42%), Gaps = 13/128 (10%)

Query: 45  SSSSTSSTSSTSSSSTTAPLLPKA---AREKPEAPAEPPGPGPGSGAHPGGSARPDAKEE 101
           SSS  S   S  +S       PK     R   +  +E   P PG     G  +    +E 
Sbjct: 5   SSSPVSPVDSLGTSEEELERQPKRFGRKRRYSKKSSEDGSPTPGKRGKKGSPSAQSFEEL 64

Query: 102 QQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYI 161
           Q Q++    N RER+R Q LN A  ALR++I           P  KLSKI TL LA  YI
Sbjct: 65  QSQRI--LANVRERQRTQSLNEAFAALRKII--------PTLPSDKLSKIQTLKLAARYI 114

Query: 162 LLLGSSLQ 169
             L   LQ
Sbjct: 115 DFLYQVLQ 122


>gi|226498192 atonal homolog 8 [Homo sapiens]
          Length = 321

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 41/124 (33%), Positives = 58/124 (46%), Gaps = 27/124 (21%)

Query: 61  TAPLLPKAAREKPEAPAEPPGPGPGSGA-------------------HPGGSARPDAKEE 101
           +AP  P A  E    PA P  PG  S +                    PG +    ++ +
Sbjct: 166 SAPPAPPAPPESTVRPAPPTRPGESSYSSISHVIYNNHQDSSASPRKRPGEATAASSEIK 225

Query: 102 QQQQLRRKI-NSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNY 160
             QQ RR + N+RER R+  ++ A +ALR+ +  YS        G+KLSK+A L +A NY
Sbjct: 226 ALQQTRRLLANARERTRVHTISAAFEALRKQVPCYSY-------GQKLSKLAILRIACNY 278

Query: 161 ILLL 164
           IL L
Sbjct: 279 ILSL 282


>gi|239751178 PREDICTED: basic helix-loop-helix family, member a9
           [Homo sapiens]
          Length = 235

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 66/205 (32%), Positives = 85/205 (41%), Gaps = 34/205 (16%)

Query: 62  APLLPKAAREKPEAPAEP---PGPGPGS-----GAHPGGSARPDAKEEQQQQLRRKINS- 112
           AP L   AR+  E  AE    P P PG      GA+    +R +A+E   ++  R + S 
Sbjct: 5   APGLGLTARKGAEDSAEDLGGPCPEPGGDSGVLGANGASCSRGEAEEPAGRRRARPVRSK 64

Query: 113 --------RERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLL 164
                   RERKR+ D N A +ALR  +      H  G  G++LSKIATL  A + I   
Sbjct: 65  ARRMAANVRERKRILDYNEAFNALRRAL-----RHDLG--GKRLSKIATLRRAIHRI--- 114

Query: 165 GSSLQELRRALGEGAGPAAPRLLLAGLPLLAAAPGSVLLAPGAVGP----PDALRPA-KY 219
            ++L  + RA     GP    L   G         +    P   GP    PDA RP+   
Sbjct: 115 -AALSLVLRASPAPRGPCG-HLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSVPS 172

Query: 220 LSLALDEPPCGQFALPGGGAGGPGL 244
                  PP    A P   A GPGL
Sbjct: 173 APRCASCPPHAPLARPSAVAEGPGL 197


>gi|239745666 PREDICTED: basic helix-loop-helix family, member a9
           [Homo sapiens]
          Length = 235

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 66/205 (32%), Positives = 85/205 (41%), Gaps = 34/205 (16%)

Query: 62  APLLPKAAREKPEAPAEP---PGPGPGS-----GAHPGGSARPDAKEEQQQQLRRKINS- 112
           AP L   AR+  E  AE    P P PG      GA+    +R +A+E   ++  R + S 
Sbjct: 5   APGLGLTARKGAEDSAEDLGGPCPEPGGDSGVLGANGASCSRGEAEEPAGRRRARPVRSK 64

Query: 113 --------RERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLL 164
                   RERKR+ D N A +ALR  +      H  G  G++LSKIATL  A + I   
Sbjct: 65  ARRMAANVRERKRILDYNEAFNALRRAL-----RHDLG--GKRLSKIATLRRAIHRI--- 114

Query: 165 GSSLQELRRALGEGAGPAAPRLLLAGLPLLAAAPGSVLLAPGAVGP----PDALRPA-KY 219
            ++L  + RA     GP    L   G         +    P   GP    PDA RP+   
Sbjct: 115 -AALSLVLRASPAPRGPCG-HLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSVPS 172

Query: 220 LSLALDEPPCGQFALPGGGAGGPGL 244
                  PP    A P   A GPGL
Sbjct: 173 APRCASCPPHAPLARPSAVAEGPGL 197


>gi|21553337 atonal homolog 7 [Homo sapiens]
          Length = 152

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 36/103 (34%), Positives = 47/103 (45%), Gaps = 12/103 (11%)

Query: 76  PAEPPG-----PGPGSGAHPGGSARPDAKEEQQQQLRRKINSRERKRMQDLNLAMDALRE 130
           P+ PP      P    G    G+     + E   + R   N+RER+RMQ LN A D LR 
Sbjct: 6   PSGPPAGARVAPPCAGGTECAGTCAGAGRLESAARRRLAANARERRRMQGLNTAFDRLRR 65

Query: 131 VILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQELRR 173
           V+        Q    +KLSK  TL +A +YI+ L   L E  R
Sbjct: 66  VV-------PQWGQDKKLSKYETLQMALSYIMALTRILAEAER 101


>gi|27475985 neurogenic differentiation 6 [Homo sapiens]
          Length = 337

 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 30/63 (47%), Positives = 39/63 (61%), Gaps = 7/63 (11%)

Query: 107 RRKINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGS 166
           R++ N+RER RM  LN A+D LR+V+  YS         +KLSKI TL LA+NYI  L  
Sbjct: 96  RQEANARERNRMHGLNDALDNLRKVVPCYSKT-------QKLSKIETLRLAKNYIWALSE 148

Query: 167 SLQ 169
            L+
Sbjct: 149 ILR 151


>gi|14149724 mesoderm posterior 1 [Homo sapiens]
          Length = 268

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 50/160 (31%), Positives = 70/160 (43%), Gaps = 23/160 (14%)

Query: 39  RQPPSSSSSSTSSTSSTSSSSTTAPLLPKAAREKPEAPAEPPGPGPG-SGAHPGGSARPD 97
           R PPS      S  SS  S  +T    P A+  +P    +P  P  G  GA    S+R  
Sbjct: 24  RPPPSDKDCGRSLVSSPDSWGSTPADSPVASPARPGTLRDPRAPSVGRRGAR---SSRLG 80

Query: 98  AKEEQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLA 157
           + +      R+  + RE+ RM+ L  A+  LR  + P  A       G+ L+KI TL LA
Sbjct: 81  SGQ------RQSASEREKLRMRTLARALHELRRFLPPSVA-----PAGQSLTKIETLRLA 129

Query: 158 RNYI----LLLGSSLQELRRALGEGAGPAAPRLLLAGLPL 193
             YI     +LG S + L+R   +     +PR    G PL
Sbjct: 130 IRYIGHLSAVLGLSEESLQRRCRQRGDAGSPR----GCPL 165


>gi|116805332 musculin [Homo sapiens]
          Length = 206

 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 45/134 (33%), Positives = 56/134 (41%), Gaps = 10/134 (7%)

Query: 42  PSSSSSSTSSTSSTSSSSTTAPLLPKAAREKPEAPAEPPGPGPGSGAHPGGSARPDAK-- 99
           PS +SS+                   A   K + P    G G G  A  GG     AK  
Sbjct: 41  PSDNSSAEEEDPDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGS 100

Query: 100 -EEQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLAR 158
             E +Q  R   N+RER RM+ L+ A   L+   LP+        P  KLSK+ TL LA 
Sbjct: 101 AAECKQSQRNAANARERARMRVLSKAFSRLK-TSLPWVP------PDTKLSKLDTLRLAS 153

Query: 159 NYILLLGSSLQELR 172
           +YI  L   LQE R
Sbjct: 154 SYIAHLRQLLQEDR 167


>gi|34147558 lymphoblastic leukemia derived sequence 1 [Homo
           sapiens]
          Length = 280

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 34/90 (37%), Positives = 47/90 (52%), Gaps = 9/90 (10%)

Query: 98  AKEEQQQQLRRKI--NSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLL 155
           A+  Q Q++ R++  NSRER R Q++N A   LR+++  +        P RKLSK   L 
Sbjct: 141 AEGHQPQKVARRVFTNSRERWRQQNVNGAFAELRKLLPTHP-------PDRKLSKNEVLR 193

Query: 156 LARNYILLLGSSLQELRRALGEGAGPAAPR 185
           LA  YI  L   L++   AL  G  P  PR
Sbjct: 194 LAMKYIGFLVRLLRDQAAALAAGPTPPGPR 223



 Score = 28.9 bits (63), Expect = 5.0
 Identities = 15/34 (44%), Positives = 19/34 (55%), Gaps = 7/34 (20%)

Query: 68  AAREKPEAPAEPPGPGPGSGAHPGGSARPDAKEE 101
           AAR +P  PA+P G        PGG+ARP   E+
Sbjct: 246 AARSQPAPPADPDGS-------PGGAARPIKMEQ 272


>gi|4885075 atonal homolog 1 [Homo sapiens]
          Length = 354

 Score = 44.7 bits (104), Expect = 9e-05
 Identities = 32/82 (39%), Positives = 43/82 (52%), Gaps = 11/82 (13%)

Query: 103 QQQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYIL 162
           Q+Q R   N+RER+RM  LN A D LR VI  ++         +KLSK  TL +A+ YI 
Sbjct: 157 QKQRRLAANARERRRMHGLNHAFDQLRNVIPSFN-------NDKKLSKYETLQMAQIYI- 208

Query: 163 LLGSSLQELRRALGEGAGPAAP 184
              ++L EL +    G  P  P
Sbjct: 209 ---NALSELLQTPSGGEQPPPP 227


>gi|239756681 PREDICTED: basic helix-loop-helix family, member a9
           [Homo sapiens]
          Length = 203

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 57/177 (32%), Positives = 76/177 (42%), Gaps = 33/177 (18%)

Query: 62  APLLPKAAREKPEAPAEP---PGPGPGS-----GAHPGGSARPDAKEEQQQQLRRKINS- 112
           AP L   AR+  E  AE    P P PG      GA+    +R +A+E   ++  R + S 
Sbjct: 5   APGLGLTARKGAEDSAEDLGGPCPEPGGDSGVLGANGASCSRGEAEEPAGRRRARPVRSK 64

Query: 113 --------RERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLL 164
                   RERKR+ D N A +ALR  +      H  G  G++LSKIATL  A + I   
Sbjct: 65  ARRMAANVRERKRILDYNEAFNALRRAL-----RHDLG--GKRLSKIATLRRAIHRI--- 114

Query: 165 GSSLQELRRALGEGAGPAAPRLLLAGLPLLAAAPGSVLLAPGAVGP----PDALRPA 217
            ++L  + RA     GP    L   G         +    P   GP    PDA RP+
Sbjct: 115 -AALSLVLRASPAPRGPCG-HLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPS 169


>gi|239749439 PREDICTED: similar to transcription factor 23 [Homo
           sapiens]
          Length = 167

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 42/119 (35%), Positives = 52/119 (43%), Gaps = 21/119 (17%)

Query: 53  SSTSSSSTTAPLLPKAAREKPEAPAEPPGP-GPGSGAHPGGSARPDAKEEQQQQLRRKIN 111
           S  S+S+  APL       +P      PGP GPG G+   GS RP A             
Sbjct: 9   SPLSASAEPAPLAAAIRDSRPGRTG--PGPAGPGGGSR-SGSGRPAAANA---------- 55

Query: 112 SRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQE 170
           +RER R+Q L  A   L+  +           P  KLSK+  LLLA  YI  L  SLQ+
Sbjct: 56  ARERSRVQTLRHAFLELQRTLPSVP-------PDTKLSKLDVLLLATTYIAHLTRSLQD 107


>gi|239743573 PREDICTED: similar to transcription factor 23 [Homo
           sapiens]
          Length = 167

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 42/119 (35%), Positives = 52/119 (43%), Gaps = 21/119 (17%)

Query: 53  SSTSSSSTTAPLLPKAAREKPEAPAEPPGP-GPGSGAHPGGSARPDAKEEQQQQLRRKIN 111
           S  S+S+  APL       +P      PGP GPG G+   GS RP A             
Sbjct: 9   SPLSASAEPAPLAAAIRDSRPGRTG--PGPAGPGGGSR-SGSGRPAAANA---------- 55

Query: 112 SRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQE 170
           +RER R+Q L  A   L+  +           P  KLSK+  LLLA  YI  L  SLQ+
Sbjct: 56  ARERSRVQTLRHAFLELQRTLPSVP-------PDTKLSKLDVLLLATTYIAHLTRSLQD 107


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.132    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,896,113
Number of Sequences: 37866
Number of extensions: 839300
Number of successful extensions: 13517
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 368
Number of HSP's successfully gapped in prelim test: 687
Number of HSP's that attempted gapping in prelim test: 9265
Number of HSP's gapped (non-prelim): 3740
length of query: 271
length of database: 18,247,518
effective HSP length: 101
effective length of query: 170
effective length of database: 14,423,052
effective search space: 2451918840
effective search space used: 2451918840
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.