BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|116174780 SEC24 related gene family, member A [Homo sapiens] (1093 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|116174780 SEC24 related gene family, member A [Homo sapiens] 2199 0.0 gi|112382214 SEC24 (S. cerevisiae) homolog B isoform b [Homo sap... 1235 0.0 gi|112382212 SEC24 (S. cerevisiae) homolog B isoform a [Homo sap... 1229 0.0 gi|38373671 SEC24-related protein C [Homo sapiens] 395 e-109 gi|38373669 SEC24-related protein C [Homo sapiens] 395 e-109 gi|190343021 Sec24-related protein D [Homo sapiens] 357 3e-98 gi|14591924 Sec23 homolog B [Homo sapiens] 75 3e-13 gi|14591926 Sec23 homolog B [Homo sapiens] 75 3e-13 gi|14591928 Sec23 homolog B [Homo sapiens] 75 3e-13 gi|38202214 SEC23-related protein A [Homo sapiens] 67 9e-11 gi|54860079 nadrin isoform 1 [Homo sapiens] 65 3e-10 gi|54860105 nadrin isoform 2 [Homo sapiens] 65 3e-10 gi|150417989 cyclin K isoform 1 [Homo sapiens] 62 3e-09 gi|163965366 nascent polypeptide-associated complex alpha subuni... 62 3e-09 gi|151301154 mucin 6, gastric [Homo sapiens] 60 1e-08 gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 59 2e-08 gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 59 3e-08 gi|188497758 ubiquitin associated protein 2-like isoform a [Homo... 59 3e-08 gi|188497756 ubiquitin associated protein 2-like isoform b [Homo... 59 3e-08 gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 58 4e-08 gi|116284392 mucin 2 precursor [Homo sapiens] 57 1e-07 gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens] 56 2e-07 gi|125858485 hypothetical protein LOC80209 isoform 2 [Homo sapiens] 55 5e-07 gi|125656155 hypothetical protein LOC80209 isoform 1 [Homo sapiens] 55 5e-07 gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 54 1e-06 gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 54 1e-06 gi|31543543 retinoic acid induced 17 [Homo sapiens] 53 1e-06 gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 52 3e-06 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 52 4e-06 gi|31543535 R3H domain containing 1 [Homo sapiens] 52 4e-06 >gi|116174780 SEC24 related gene family, member A [Homo sapiens] Length = 1093 Score = 2199 bits (5698), Expect = 0.0 Identities = 1093/1093 (100%), Positives = 1093/1093 (100%) Query: 1 MSQPGIPASGGAPASLQAQNGAALASGSPYTNGPVQNALLSSQESVSQGYNFQLPGSYPH 60 MSQPGIPASGGAPASLQAQNGAALASGSPYTNGPVQNALLSSQESVSQGYNFQLPGSYPH Sbjct: 1 MSQPGIPASGGAPASLQAQNGAALASGSPYTNGPVQNALLSSQESVSQGYNFQLPGSYPH 60 Query: 61 PIPAKTLNPVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAPRMPLPASQNPATTP 120 PIPAKTLNPVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAPRMPLPASQNPATTP Sbjct: 61 PIPAKTLNPVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAPRMPLPASQNPATTP 120 Query: 121 MPSSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSGYPS 180 MPSSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSGYPS Sbjct: 121 MPSSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSGYPS 180 Query: 181 LQNSFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGGPPPVRALTPLTSSYRDVPQPLFN 240 LQNSFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGGPPPVRALTPLTSSYRDVPQPLFN Sbjct: 181 LQNSFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGGPPPVRALTPLTSSYRDVPQPLFN 240 Query: 241 SAVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQLTNKNPKMSRSVGYSYPSLPPGYQ 300 SAVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQLTNKNPKMSRSVGYSYPSLPPGYQ Sbjct: 241 SAVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQLTNKNPKMSRSVGYSYPSLPPGYQ 300 Query: 301 NTTPPGATGVPPSSLNYPSGPQAFTQTPLGANHLTTSMSGLSLQPEGLRVVNLLQERNML 360 NTTPPGATGVPPSSLNYPSGPQAFTQTPLGANHLTTSMSGLSLQPEGLRVVNLLQERNML Sbjct: 301 NTTPPGATGVPPSSLNYPSGPQAFTQTPLGANHLTTSMSGLSLQPEGLRVVNLLQERNML 360 Query: 361 PSTPLKPPVPNLHEDIQKLNCNPELFRCTLTSIPQTQALLNKAKLPLGLLLHPFKDLVQL 420 PSTPLKPPVPNLHEDIQKLNCNPELFRCTLTSIPQTQALLNKAKLPLGLLLHPFKDLVQL Sbjct: 361 PSTPLKPPVPNLHEDIQKLNCNPELFRCTLTSIPQTQALLNKAKLPLGLLLHPFKDLVQL 420 Query: 421 PVVTSSTIVRCRSCRTYINPFVSFLDQRRWKCNLCYRVNDVPEEFLYNPLTRVYGEPHRR 480 PVVTSSTIVRCRSCRTYINPFVSFLDQRRWKCNLCYRVNDVPEEFLYNPLTRVYGEPHRR Sbjct: 421 PVVTSSTIVRCRSCRTYINPFVSFLDQRRWKCNLCYRVNDVPEEFLYNPLTRVYGEPHRR 480 Query: 481 PEVQNATIEFMAPSEYMLRPPQPPVYLFVFDVSHNAVETGYLNSVCQSLLDNLDLLPGNT 540 PEVQNATIEFMAPSEYMLRPPQPPVYLFVFDVSHNAVETGYLNSVCQSLLDNLDLLPGNT Sbjct: 481 PEVQNATIEFMAPSEYMLRPPQPPVYLFVFDVSHNAVETGYLNSVCQSLLDNLDLLPGNT 540 Query: 541 RTKIGFITFDSTIHFYGLQESLSQPQMLIVSDIEDVFIPMPENLLVNLNESKELVQDLLK 600 RTKIGFITFDSTIHFYGLQESLSQPQMLIVSDIEDVFIPMPENLLVNLNESKELVQDLLK Sbjct: 541 RTKIGFITFDSTIHFYGLQESLSQPQMLIVSDIEDVFIPMPENLLVNLNESKELVQDLLK 600 Query: 601 TLPQMFTKTLETQSALGPALQAAFKLMSPTGGRMSVFQTQLPTLGVGALKPREEPNHRSS 660 TLPQMFTKTLETQSALGPALQAAFKLMSPTGGRMSVFQTQLPTLGVGALKPREEPNHRSS Sbjct: 601 TLPQMFTKTLETQSALGPALQAAFKLMSPTGGRMSVFQTQLPTLGVGALKPREEPNHRSS 660 Query: 661 AKDIHMTPSTDFYKKLALDCSGQQVAVDLFLLSGQYSDLASLGCISRYSAGSVYYYPSYH 720 AKDIHMTPSTDFYKKLALDCSGQQVAVDLFLLSGQYSDLASLGCISRYSAGSVYYYPSYH Sbjct: 661 AKDIHMTPSTDFYKKLALDCSGQQVAVDLFLLSGQYSDLASLGCISRYSAGSVYYYPSYH 720 Query: 721 HQHNPVQVQKLQKELQRYLTRKIGFEAVMRIRCTKGLSIHTFHGNFFVRSTDLLSLPNVN 780 HQHNPVQVQKLQKELQRYLTRKIGFEAVMRIRCTKGLSIHTFHGNFFVRSTDLLSLPNVN Sbjct: 721 HQHNPVQVQKLQKELQRYLTRKIGFEAVMRIRCTKGLSIHTFHGNFFVRSTDLLSLPNVN 780 Query: 781 PDAGYAVQMSVEESLTDTQLVSFQSALLYTSSKGERRIRVHTLCLPVVSTLNDVFLGADV 840 PDAGYAVQMSVEESLTDTQLVSFQSALLYTSSKGERRIRVHTLCLPVVSTLNDVFLGADV Sbjct: 781 PDAGYAVQMSVEESLTDTQLVSFQSALLYTSSKGERRIRVHTLCLPVVSTLNDVFLGADV 840 Query: 841 QAISGLLANMAVDRSMTASLSDARDALVNAVIDSLSAYRSSVLSNQQPGLMVPFSLRLFP 900 QAISGLLANMAVDRSMTASLSDARDALVNAVIDSLSAYRSSVLSNQQPGLMVPFSLRLFP Sbjct: 841 QAISGLLANMAVDRSMTASLSDARDALVNAVIDSLSAYRSSVLSNQQPGLMVPFSLRLFP 900 Query: 901 LFVLALLKQKSFQTGTNARLDERIFAMCQVKNQPLVYLMLTTHPSLYRVDNLSDEGALNI 960 LFVLALLKQKSFQTGTNARLDERIFAMCQVKNQPLVYLMLTTHPSLYRVDNLSDEGALNI Sbjct: 901 LFVLALLKQKSFQTGTNARLDERIFAMCQVKNQPLVYLMLTTHPSLYRVDNLSDEGALNI 960 Query: 961 SDRTIPQPPILQLSVEKLSRDGAFLMDAGSVLMLWVGKNCTQNFLSQVLGVQNYASIPQP 1020 SDRTIPQPPILQLSVEKLSRDGAFLMDAGSVLMLWVGKNCTQNFLSQVLGVQNYASIPQP Sbjct: 961 SDRTIPQPPILQLSVEKLSRDGAFLMDAGSVLMLWVGKNCTQNFLSQVLGVQNYASIPQP 1020 Query: 1021 MTDLPELDTPESARIIAFISWLREQRPFFPILYVIRDESPMKANFLQNMIEDRTESALSY 1080 MTDLPELDTPESARIIAFISWLREQRPFFPILYVIRDESPMKANFLQNMIEDRTESALSY Sbjct: 1021 MTDLPELDTPESARIIAFISWLREQRPFFPILYVIRDESPMKANFLQNMIEDRTESALSY 1080 Query: 1081 YEFLLHIQQQVNK 1093 YEFLLHIQQQVNK Sbjct: 1081 YEFLLHIQQQVNK 1093 >gi|112382214 SEC24 (S. cerevisiae) homolog B isoform b [Homo sapiens] Length = 1233 Score = 1235 bits (3195), Expect = 0.0 Identities = 663/1130 (58%), Positives = 814/1130 (72%), Gaps = 79/1130 (6%) Query: 11 GAPASLQAQNGAALASGSPYTNGPVQNALLSSQESV-SQGYNFQLPGSYPHPIPAKTLNP 69 GA +S + +A S + N A+ S+ SV SQG+ P + H + N Sbjct: 136 GAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGF----PSTCGHYAMSTVSNA 191 Query: 70 VSGQSNY-----GGSQGSGQTLNRPPVASNPVTPSLHSG-------PAPRMPLPASQNPA 117 +Y G + G T P PV + SG P+P PLP+ Q+ Sbjct: 192 AYPSVSYPSLPAGDTYGQMFTSQNAPTV-RPVKDNSFSGQNTAISHPSPLPPLPSQQHHQ 250 Query: 118 TTPMPSSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSG 177 + S L ++ P + Q N + T A++ PT++ SL+ Sbjct: 251 QQSLSGYSTLTWSSPGLP-STQDNL--IRNHTGSLAVANNNPTITVADSLSC-------- 299 Query: 178 YPSLQNSFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGGPPPVRALTPLTSSYRDVPQP 237 P +QN P P+V+ L + + PP A P + P+TS V QP Sbjct: 300 -PVMQNV---QPPKSSPVVSTVLSGSSGSSSTRTPPTANHP-----VEPVTS----VTQP 346 Query: 238 LFNSAVNQEGI-TSNTNNGSMVVHSSYDEIEGGGLLATPQLTNKNP-------------- 282 + + Q+G+ +S+T + + + +SYD +EGG + +P Sbjct: 347 --SELLQQKGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAP 404 Query: 283 --------------KMSRSVGYSYPSLPPGYQNTTPPGATGVPPSSLNYPSGPQAFTQTP 328 KM++ GY YP+L PGYQN T P +GV PS+ Y SG Q + Q Sbjct: 405 APASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPLISGVQPSNPVY-SGFQQYPQQY 463 Query: 329 LGANHLTTSMSGLSLQ----PEGLRVVNLLQERNMLPSTPLKPPVPNLHEDIQKLNCNPE 384 G N L++S+ GLSLQ PE LR VNL QERN+LP TP+ PVPNL+ D++KLNC+P+ Sbjct: 464 PGVNQLSSSIGGLSLQSSPQPESLRPVNLTQERNILPMTPVWAPVPNLNADLKKLNCSPD 523 Query: 385 LFRCTLTSIPQTQALLNKAKLPLGLLLHPFKDLVQLPVVTSSTIVRCRSCRTYINPFVSF 444 FRCTLT+IPQTQALLNKAKLPLGLLLHPF+DL QLPV+TS+TIVRCRSCRTYINPFVSF Sbjct: 524 SFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDLTQLPVITSNTIVRCRSCRTYINPFVSF 583 Query: 445 LDQRRWKCNLCYRVNDVPEEFLYNPLTRVYGEPHRRPEVQNATIEFMAPSEYMLRPPQPP 504 +DQRRWKCNLCYRVNDVPEEF+YNPLTR YGEPH+RPEVQN+T+EF+A S+YMLRPPQP Sbjct: 584 IDQRRWKCNLCYRVNDVPEEFMYNPLTRSYGEPHKRPEVQNSTVEFIASSDYMLRPPQPA 643 Query: 505 VYLFVFDVSHNAVETGYLNSVCQSLLDNLDLLPGNTRTKIGFITFDSTIHFYGLQESLSQ 564 VYLFV DVSHNAVE GYL +CQSLL+NLD LPG++RT+IGF+TFDSTIHFY LQE LSQ Sbjct: 644 VYLFVLDVSHNAVEAGYLTILCQSLLENLDKLPGDSRTRIGFMTFDSTIHFYNLQEGLSQ 703 Query: 565 PQMLIVSDIEDVFIPMPENLLVNLNESKELVQDLLKTLPQMFTKTLETQSALGPALQAAF 624 PQMLIVSDI+DVF+P P++LLVNL ESKEL++DLL LP MFT T ET SALGPALQAAF Sbjct: 704 PQMLIVSDIDDVFLPTPDSLLVNLYESKELIKDLLNALPNMFTNTRETHSALGPALQAAF 763 Query: 625 KLMSPTGGRMSVFQTQLPTLGVGALKPREEPNHRSSAKDI-HMTPSTDFYKKLALDCSGQ 683 KLMSPTGGR+SVFQTQLP+LG G L+ RE+PN RSS K + H+ P+TDFYKKLALDCSGQ Sbjct: 764 KLMSPTGGRVSVFQTQLPSLGAGLLQSREDPNQRSSTKVVQHLGPATDFYKKLALDCSGQ 823 Query: 684 QVAVDLFLLSGQYSDLASLGCISRYSAGSVYYYPSYHHQHNPVQVQKLQKELQRYLTRKI 743 Q AVDLFLLS QYSDLASL C+S+YSAG +YYYPS+H+ HNP Q +KLQK+L+RYLTRKI Sbjct: 824 QTAVDLFLLSSQYSDLASLACMSKYSAGCIYYYPSFHYTHNPSQAEKLQKDLKRYLTRKI 883 Query: 744 GFEAVMRIRCTKGLSIHTFHGNFFVRSTDLLSLPNVNPDAGYAVQMSVEESLTDTQLVSF 803 GFEAVMRIRCTKGLS+HTFHGNFFVRSTDLLSL N+NPDAG+AVQ+S+EESLTDT LV F Sbjct: 884 GFEAVMRIRCTKGLSMHTFHGNFFVRSTDLLSLANINPDAGFAVQLSIEESLTDTSLVCF 943 Query: 804 QSALLYTSSKGERRIRVHTLCLPVVSTLNDVFLGADVQAISGLLANMAVDRSMTASLSDA 863 Q+ALLYTSSKGERRIRVHTLCLPVVS+L DV+ G DVQA LLANMAVDRS+++SLSDA Sbjct: 944 QTALLYTSSKGERRIRVHTLCLPVVSSLADVYAGVDVQAAICLLANMAVDRSVSSSLSDA 1003 Query: 864 RDALVNAVIDSLSAYRSSVLSNQQPGLMVPFSLRLFPLFVLALLKQKSFQTGTNARLDER 923 RDALVNAV+DSLSAY S+V + Q LM P SL+LFPL+VLALLKQK+F+TGT+ RLD+R Sbjct: 1004 RDALVNAVVDSLSAYGSTVSNLQHSALMAPSSLKLFPLYVLALLKQKAFRTGTSTRLDDR 1063 Query: 924 IFAMCQVKNQPLVYLMLTTHPSLYRVDNLSDEGALNISDRTIPQPPILQLSVEKLSRDGA 983 ++AMCQ+K+QPLV+LM HP+LYR+D L+DEGA++++DR +PQPP+ +LS EKL+R+GA Sbjct: 1064 VYAMCQIKSQPLVHLMKMIHPNLYRIDRLTDEGAVHVNDRIVPQPPLQKLSAEKLTREGA 1123 Query: 984 FLMDAGSVLMLWVGKNCTQNFLSQVLGVQNYASIPQPMTDLPELDTPESARIIAFISWLR 1043 FLMD GSV +WVGK C NF+ VLG N+ASIPQ MT LPELDT S R +FI+WLR Sbjct: 1124 FLMDCGSVFYIWVGKGCDNNFIEDVLGYTNFASIPQKMTHLPELDTLSSERARSFITWLR 1183 Query: 1044 EQRPFFPILYVIRDESPMKANFLQNMIEDRTESALSYYEFLLHIQQQVNK 1093 + RP PIL++++DESP KA F Q++IEDRTE+A SYYEFLLH+QQQ+ K Sbjct: 1184 DSRPLSPILHIVKDESPAKAEFFQHLIEDRTEAAFSYYEFLLHVQQQICK 1233 >gi|112382212 SEC24 (S. cerevisiae) homolog B isoform a [Homo sapiens] Length = 1268 Score = 1229 bits (3180), Expect = 0.0 Identities = 663/1154 (57%), Positives = 818/1154 (70%), Gaps = 92/1154 (7%) Query: 11 GAPASLQAQNGAALASGSPYTNGPVQNALLSSQESV-SQGYNFQLPGSYPHPIPAKTLNP 69 GA +S + +A S + N A+ S+ SV SQG+ P + H + N Sbjct: 136 GAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGF----PSTCGHYAMSTVSNA 191 Query: 70 VSGQSNY-----GGSQGSGQTLNRPPVASNPVTPSLHSG-------PAPRMPLPASQNPA 117 +Y G + G T P PV + SG P+P PLP+ Q+ Sbjct: 192 AYPSVSYPSLPAGDTYGQMFTSQNAPTV-RPVKDNSFSGQNTAISHPSPLPPLPSQQHHQ 250 Query: 118 TTPMPSSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSG 177 + S L ++ P + Q N + T A++ PT++ SL+ Sbjct: 251 QQSLSGYSTLTWSSPGLP-STQDNL--IRNHTGSLAVANNNPTITVADSLSC-------- 299 Query: 178 YPSLQNSFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGGP-PPVRALTP---------- 226 P +QN P P+V+ L + + PP A P PV ++T Sbjct: 300 -PVMQNV---QPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGV 355 Query: 227 -----LTSSYRDVPQPLFNSAVNQE--------GI-TSNTNNGSMVVHSSYDEIEGGGLL 272 + + P PL +++ ++E G+ +S+T + + + +SYD +EGG Sbjct: 356 QYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYP 415 Query: 273 ATPQLTNKNP----------------------------KMSRSVGYSYPSLPPGYQNTTP 304 + +P KM++ GY YP+L PGYQN T Sbjct: 416 DMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATA 475 Query: 305 PGATGVPPSSLNYPSGPQAFTQTPLGANHLTTSMSGLSLQ----PEGLRVVNLLQERNML 360 P +GV PS+ Y SG Q + Q G N L++S+ GLSLQ PE LR VNL QERN+L Sbjct: 476 PLISGVQPSNPVY-SGFQQYPQQYPGVNQLSSSIGGLSLQSSPQPESLRPVNLTQERNIL 534 Query: 361 PSTPLKPPVPNLHEDIQKLNCNPELFRCTLTSIPQTQALLNKAKLPLGLLLHPFKDLVQL 420 P TP+ PVPNL+ D++KLNC+P+ FRCTLT+IPQTQALLNKAKLPLGLLLHPF+DL QL Sbjct: 535 PMTPVWAPVPNLNADLKKLNCSPDSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDLTQL 594 Query: 421 PVVTSSTIVRCRSCRTYINPFVSFLDQRRWKCNLCYRVNDVPEEFLYNPLTRVYGEPHRR 480 PV+TS+TIVRCRSCRTYINPFVSF+DQRRWKCNLCYRVNDVPEEF+YNPLTR YGEPH+R Sbjct: 595 PVITSNTIVRCRSCRTYINPFVSFIDQRRWKCNLCYRVNDVPEEFMYNPLTRSYGEPHKR 654 Query: 481 PEVQNATIEFMAPSEYMLRPPQPPVYLFVFDVSHNAVETGYLNSVCQSLLDNLDLLPGNT 540 PEVQN+T+EF+A S+YMLRPPQP VYLFV DVSHNAVE GYL +CQSLL+NLD LPG++ Sbjct: 655 PEVQNSTVEFIASSDYMLRPPQPAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLPGDS 714 Query: 541 RTKIGFITFDSTIHFYGLQESLSQPQMLIVSDIEDVFIPMPENLLVNLNESKELVQDLLK 600 RT+IGF+TFDSTIHFY LQE LSQPQMLIVSDI+DVF+P P++LLVNL ESKEL++DLL Sbjct: 715 RTRIGFMTFDSTIHFYNLQEGLSQPQMLIVSDIDDVFLPTPDSLLVNLYESKELIKDLLN 774 Query: 601 TLPQMFTKTLETQSALGPALQAAFKLMSPTGGRMSVFQTQLPTLGVGALKPREEPNHRSS 660 LP MFT T ET SALGPALQAAFKLMSPTGGR+SVFQTQLP+LG G L+ RE+PN RSS Sbjct: 775 ALPNMFTNTRETHSALGPALQAAFKLMSPTGGRVSVFQTQLPSLGAGLLQSREDPNQRSS 834 Query: 661 AKDI-HMTPSTDFYKKLALDCSGQQVAVDLFLLSGQYSDLASLGCISRYSAGSVYYYPSY 719 K + H+ P+TDFYKKLALDCSGQQ AVDLFLLS QYSDLASL C+S+YSAG +YYYPS+ Sbjct: 835 TKVVQHLGPATDFYKKLALDCSGQQTAVDLFLLSSQYSDLASLACMSKYSAGCIYYYPSF 894 Query: 720 HHQHNPVQVQKLQKELQRYLTRKIGFEAVMRIRCTKGLSIHTFHGNFFVRSTDLLSLPNV 779 H+ HNP Q +KLQK+L+RYLTRKIGFEAVMRIRCTKGLS+HTFHGNFFVRSTDLLSL N+ Sbjct: 895 HYTHNPSQAEKLQKDLKRYLTRKIGFEAVMRIRCTKGLSMHTFHGNFFVRSTDLLSLANI 954 Query: 780 NPDAGYAVQMSVEESLTDTQLVSFQSALLYTSSKGERRIRVHTLCLPVVSTLNDVFLGAD 839 NPDAG+AVQ+S+EESLTDT LV FQ+ALLYTSSKGERRIRVHTLCLPVVS+L DV+ G D Sbjct: 955 NPDAGFAVQLSIEESLTDTSLVCFQTALLYTSSKGERRIRVHTLCLPVVSSLADVYAGVD 1014 Query: 840 VQAISGLLANMAVDRSMTASLSDARDALVNAVIDSLSAYRSSVLSNQQPGLMVPFSLRLF 899 VQA LLANMAVDRS+++SLSDARDALVNAV+DSLSAY S+V + Q LM P SL+LF Sbjct: 1015 VQAAICLLANMAVDRSVSSSLSDARDALVNAVVDSLSAYGSTVSNLQHSALMAPSSLKLF 1074 Query: 900 PLFVLALLKQKSFQTGTNARLDERIFAMCQVKNQPLVYLMLTTHPSLYRVDNLSDEGALN 959 PL+VLALLKQK+F+TGT+ RLD+R++AMCQ+K+QPLV+LM HP+LYR+D L+DEGA++ Sbjct: 1075 PLYVLALLKQKAFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPNLYRIDRLTDEGAVH 1134 Query: 960 ISDRTIPQPPILQLSVEKLSRDGAFLMDAGSVLMLWVGKNCTQNFLSQVLGVQNYASIPQ 1019 ++DR +PQPP+ +LS EKL+R+GAFLMD GSV +WVGK C NF+ VLG N+ASIPQ Sbjct: 1135 VNDRIVPQPPLQKLSAEKLTREGAFLMDCGSVFYIWVGKGCDNNFIEDVLGYTNFASIPQ 1194 Query: 1020 PMTDLPELDTPESARIIAFISWLREQRPFFPILYVIRDESPMKANFLQNMIEDRTESALS 1079 MT LPELDT S R +FI+WLR+ RP PIL++++DESP KA F Q++IEDRTE+A S Sbjct: 1195 KMTHLPELDTLSSERARSFITWLRDSRPLSPILHIVKDESPAKAEFFQHLIEDRTEAAFS 1254 Query: 1080 YYEFLLHIQQQVNK 1093 YYEFLLH+QQQ+ K Sbjct: 1255 YYEFLLHVQQQICK 1268 >gi|38373671 SEC24-related protein C [Homo sapiens] Length = 1094 Score = 395 bits (1015), Expect = e-109 Identities = 312/1130 (27%), Positives = 510/1130 (45%), Gaps = 144/1130 (12%) Query: 7 PASGGAPASLQAQNGAALASGSPYTNGPVQNALLSSQESVSQGYNFQLPGSYPHPIPAKT 66 P S GAP + AQ A+ + G VQN S+ + +LPGS P P Sbjct: 63 PPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQ------RLPGSQPFGSP--- 113 Query: 67 LNPVSGQ----SNYGGSQGSGQTLNR-------PPVASNPVTPSLHSGPAPRMPLPASQN 115 L PV Q YG S Q + VA P + L GP P S Sbjct: 114 LAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGP------PTSLA 167 Query: 116 PATTPMPSSSFL---PEANLPPPLNWQYNYPSTASQTNHCPRASSQ--PTVSGNTSLTTN 170 A+ P+S P+ PP L+ +P + P +S P SG Sbjct: 168 SASGSFPNSGLYGSYPQGQAPP-LSQAQGHPGIQTPQRSAPSQASSFTPPASG------- 219 Query: 171 HQYVSSGYPSLQNSFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGGPPPVRALTPLTSS 230 GP +P + P LP G P PP +AL P T Sbjct: 220 ------------------GPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPP-QALPPGTQM 260 Query: 231 YRDV-PQPLFNSAVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQLTNKNPKMSRSVG 289 + P P +S Q+ NGS G PQ P Sbjct: 261 TGPLGPLPPMHSP--QQPGYQPQQNGSF------------GPARGPQSNYGGP------- 299 Query: 290 YSYPSLPPGYQNTTPPGATGVPPSSLNYPSGPQAFTQTPLGANHLTTS--MSGLSLQPEG 347 YP+ P PP +PP L+ + P N+ T ++G+ Q Sbjct: 300 --YPAAPTFGSQPGPPQP--LPPKRLDPDAIPSPIQVIEDDRNNRGTEPFVTGVRGQVPP 355 Query: 348 LRVVNLLQERNMLPSTPLKPPVPNLHEDIQKLNCNPELFRCTLTSIPQTQALLNKAKLPL 407 L N L + + N +P RCT +IP T + +A++PL Sbjct: 356 LVTTNFLVK--------------------DQGNASPRYIRCTSYNIPCTSDMAKQAQVPL 395 Query: 408 GLLLHPFKDLVQLPVVTSSTIV---------RCRSCRTYINPFVSFLDQ-RRWKCNLCYR 457 ++ P L +LP +S V RC C+ Y+ PF+ F++ RR++C C Sbjct: 396 AAVIKP---LARLPPEEASPYVVDHGESGPLRCNRCKAYMCPFMQFIEGGRRFQCCFCSC 452 Query: 458 VNDVPEEFLYN-PLTRVYGEPHRRPEVQNATIEFMAPSEYMLRP--PQPPVYLFVFDVSH 514 +NDVP ++ + T + + RPE+ + EF+A +Y P PP ++F+ DVS+ Sbjct: 453 INDVPPQYFQHLDHTGKRVDAYDRPELSLGSYEFLATVDYCKNNKFPSPPAFIFMIDVSY 512 Query: 515 NAVETGYLNSVCQSLLDNLDLLPGN-----TRTKIGFITFDSTIHFYGLQESLSQPQMLI 569 NA+ TG + +C+ L LD LP + ++GF+T++ +HFY ++ SL+QPQM++ Sbjct: 513 NAIRTGLVRLLCEELKSLLDFLPREGGAEESAIRVGFVTYNKVLHFYNVKSSLAQPQMMV 572 Query: 570 VSDIEDVFIPMPENLLVNLNESKELVQDLLKTLPQMFTKTLETQSALGPALQAAFKLM-- 627 VSD+ D+F+P+ + LVN+NES+ ++ LL +P+MF T ET++ P +QA + + Sbjct: 573 VSDVADMFVPLLDGFLVNVNESRAVITSLLDQIPEMFADTRETETVFVPVIQAGMEALKA 632 Query: 628 SPTGGRMSVFQTQLPTL-GVGALKPREEPNHRSSAKDIHM-TPSTDFYKKLALDCSGQQV 685 + G++ +F T LP G LK R++ ++ K+ + P T Y+ LA +C Q Sbjct: 633 AECAGKLFLFHTSLPIAEAPGKLKNRDDRKLINTDKEKTLFQPQTGAYQTLAKECVAQGC 692 Query: 686 AVDLFLLSGQYSDLASLGCISRYSAGSVYYYPSYHHQHNPVQVQKLQKELQRYLTRKIGF 745 VDLFL QY D+A+L + + + GSVY Y S+ +++ ++ +L+R + + +GF Sbjct: 693 CVDLFLFPNQYVDVATLSVVPQLTGGSVYKYASFQVENDQ---ERFLSDLRRDVQKVVGF 749 Query: 746 EAVMRIRCTKGLSIHTFHGNFFVRSTDLLSLPNVNPDAGYAVQMSVEESLTDTQLVSFQS 805 +AVMR+R + G+ F G F++ +T + L ++ D V+ ++ L + Q Sbjct: 750 DAVMRVRTSTGIRAVDFFGAFYMSNTTDVELAGLDGDKTVTVEFKHDDRLNEESGALLQC 809 Query: 806 ALLYTSSKGERRIRVHTLCLPVVSTLNDVFLGADVQAISGLLANMAVDRSMTASLSDARD 865 ALLYTS G+RR+R+H L L + L D++ + + +A A + + + RD Sbjct: 810 ALLYTSCAGQRRLRIHNLALNCCTQLADLYRNCETDTLINYMAKFAYRGVLNSPVKAVRD 869 Query: 866 ALVNAVIDSLSAYRSSVLSNQQPG-LMVPFSLRLFPLFVLALLKQKSFQTGTNARLDERI 924 L+ L+ YR + S G L++P ++L P+++ +LK Q G D+R Sbjct: 870 TLITQCAQILACYRKNCASPSSAGQLILPECMKLLPVYLNCVLKSDVLQPGAEVTTDDRA 929 Query: 925 FAMCQVKNQPLVYLMLTTHPSLYRVDNLSDEGALNISDRTIPQPPILQLSVEKLSRDGAF 984 + V + + + +P L + E + +PP ++ S E+LS + Sbjct: 930 YVRQLVTSMDVTETNVFFYPRLLPLTKSPVE--------STTEPPAVRASEERLSNGDIY 981 Query: 985 LMDAGSVLMLWVGKNCTQNFLSQVLGVQNYASIPQPMTDLPELDTPESARIIAFISWLRE 1044 L++ G L LWVG + Q + + V +++ I ++ LP LD P S ++ I LR Sbjct: 982 LLENGLNLFLWVGASVQQGVVQSLFSVSSFSQITSGLSVLPVLDNPLSKKVRGLIDSLRA 1041 Query: 1045 QRPFFPILYVIRDESPMKANFLQNMIEDRTES-ALSYYEFLLHIQQQVNK 1093 QR + L V++ E M+ F ++ED++ S SY +FL H+ +++ + Sbjct: 1042 QRSRYMKLTVVKQEDKMEMLFKHFLVEDKSLSGGASYVDFLCHMHKEIRQ 1091 Score = 42.4 bits (98), Expect = 0.002 Identities = 52/171 (30%), Positives = 71/171 (41%), Gaps = 26/171 (15%) Query: 4 PGIPASG---GAPASLQAQNGAALASG--SPYTNG---PVQNA-----LLSSQESV-SQG 49 P P+SG G P SL + +G+ SG Y G P+ A + + Q S SQ Sbjct: 151 PAPPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQA 210 Query: 50 YNFQLPGSYPHPIPAKTLNPVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGP-APRM 108 +F P S +P+ T + GQS G S ++ PP A P T +GP P Sbjct: 211 SSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQM--TGPLGPLP 268 Query: 109 PLPASQNPATTPMPSSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQP 159 P+ + Q P P + SF P P N+ YP+ P SQP Sbjct: 269 PMHSPQQPGYQPQQNGSFGPARG--PQSNYGGPYPA-------APTFGSQP 310 >gi|38373669 SEC24-related protein C [Homo sapiens] Length = 1094 Score = 395 bits (1015), Expect = e-109 Identities = 312/1130 (27%), Positives = 510/1130 (45%), Gaps = 144/1130 (12%) Query: 7 PASGGAPASLQAQNGAALASGSPYTNGPVQNALLSSQESVSQGYNFQLPGSYPHPIPAKT 66 P S GAP + AQ A+ + G VQN S+ + +LPGS P P Sbjct: 63 PPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQ------RLPGSQPFGSP--- 113 Query: 67 LNPVSGQ----SNYGGSQGSGQTLNR-------PPVASNPVTPSLHSGPAPRMPLPASQN 115 L PV Q YG S Q + VA P + L GP P S Sbjct: 114 LAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGP------PTSLA 167 Query: 116 PATTPMPSSSFL---PEANLPPPLNWQYNYPSTASQTNHCPRASSQ--PTVSGNTSLTTN 170 A+ P+S P+ PP L+ +P + P +S P SG Sbjct: 168 SASGSFPNSGLYGSYPQGQAPP-LSQAQGHPGIQTPQRSAPSQASSFTPPASG------- 219 Query: 171 HQYVSSGYPSLQNSFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGGPPPVRALTPLTSS 230 GP +P + P LP G P PP +AL P T Sbjct: 220 ------------------GPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPP-QALPPGTQM 260 Query: 231 YRDV-PQPLFNSAVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQLTNKNPKMSRSVG 289 + P P +S Q+ NGS G PQ P Sbjct: 261 TGPLGPLPPMHSP--QQPGYQPQQNGSF------------GPARGPQSNYGGP------- 299 Query: 290 YSYPSLPPGYQNTTPPGATGVPPSSLNYPSGPQAFTQTPLGANHLTTS--MSGLSLQPEG 347 YP+ P PP +PP L+ + P N+ T ++G+ Q Sbjct: 300 --YPAAPTFGSQPGPPQP--LPPKRLDPDAIPSPIQVIEDDRNNRGTEPFVTGVRGQVPP 355 Query: 348 LRVVNLLQERNMLPSTPLKPPVPNLHEDIQKLNCNPELFRCTLTSIPQTQALLNKAKLPL 407 L N L + + N +P RCT +IP T + +A++PL Sbjct: 356 LVTTNFLVK--------------------DQGNASPRYIRCTSYNIPCTSDMAKQAQVPL 395 Query: 408 GLLLHPFKDLVQLPVVTSSTIV---------RCRSCRTYINPFVSFLDQ-RRWKCNLCYR 457 ++ P L +LP +S V RC C+ Y+ PF+ F++ RR++C C Sbjct: 396 AAVIKP---LARLPPEEASPYVVDHGESGPLRCNRCKAYMCPFMQFIEGGRRFQCCFCSC 452 Query: 458 VNDVPEEFLYN-PLTRVYGEPHRRPEVQNATIEFMAPSEYMLRP--PQPPVYLFVFDVSH 514 +NDVP ++ + T + + RPE+ + EF+A +Y P PP ++F+ DVS+ Sbjct: 453 INDVPPQYFQHLDHTGKRVDAYDRPELSLGSYEFLATVDYCKNNKFPSPPAFIFMIDVSY 512 Query: 515 NAVETGYLNSVCQSLLDNLDLLPGN-----TRTKIGFITFDSTIHFYGLQESLSQPQMLI 569 NA+ TG + +C+ L LD LP + ++GF+T++ +HFY ++ SL+QPQM++ Sbjct: 513 NAIRTGLVRLLCEELKSLLDFLPREGGAEESAIRVGFVTYNKVLHFYNVKSSLAQPQMMV 572 Query: 570 VSDIEDVFIPMPENLLVNLNESKELVQDLLKTLPQMFTKTLETQSALGPALQAAFKLM-- 627 VSD+ D+F+P+ + LVN+NES+ ++ LL +P+MF T ET++ P +QA + + Sbjct: 573 VSDVADMFVPLLDGFLVNVNESRAVITSLLDQIPEMFADTRETETVFVPVIQAGMEALKA 632 Query: 628 SPTGGRMSVFQTQLPTL-GVGALKPREEPNHRSSAKDIHM-TPSTDFYKKLALDCSGQQV 685 + G++ +F T LP G LK R++ ++ K+ + P T Y+ LA +C Q Sbjct: 633 AECAGKLFLFHTSLPIAEAPGKLKNRDDRKLINTDKEKTLFQPQTGAYQTLAKECVAQGC 692 Query: 686 AVDLFLLSGQYSDLASLGCISRYSAGSVYYYPSYHHQHNPVQVQKLQKELQRYLTRKIGF 745 VDLFL QY D+A+L + + + GSVY Y S+ +++ ++ +L+R + + +GF Sbjct: 693 CVDLFLFPNQYVDVATLSVVPQLTGGSVYKYASFQVENDQ---ERFLSDLRRDVQKVVGF 749 Query: 746 EAVMRIRCTKGLSIHTFHGNFFVRSTDLLSLPNVNPDAGYAVQMSVEESLTDTQLVSFQS 805 +AVMR+R + G+ F G F++ +T + L ++ D V+ ++ L + Q Sbjct: 750 DAVMRVRTSTGIRAVDFFGAFYMSNTTDVELAGLDGDKTVTVEFKHDDRLNEESGALLQC 809 Query: 806 ALLYTSSKGERRIRVHTLCLPVVSTLNDVFLGADVQAISGLLANMAVDRSMTASLSDARD 865 ALLYTS G+RR+R+H L L + L D++ + + +A A + + + RD Sbjct: 810 ALLYTSCAGQRRLRIHNLALNCCTQLADLYRNCETDTLINYMAKFAYRGVLNSPVKAVRD 869 Query: 866 ALVNAVIDSLSAYRSSVLSNQQPG-LMVPFSLRLFPLFVLALLKQKSFQTGTNARLDERI 924 L+ L+ YR + S G L++P ++L P+++ +LK Q G D+R Sbjct: 870 TLITQCAQILACYRKNCASPSSAGQLILPECMKLLPVYLNCVLKSDVLQPGAEVTTDDRA 929 Query: 925 FAMCQVKNQPLVYLMLTTHPSLYRVDNLSDEGALNISDRTIPQPPILQLSVEKLSRDGAF 984 + V + + + +P L + E + +PP ++ S E+LS + Sbjct: 930 YVRQLVTSMDVTETNVFFYPRLLPLTKSPVE--------STTEPPAVRASEERLSNGDIY 981 Query: 985 LMDAGSVLMLWVGKNCTQNFLSQVLGVQNYASIPQPMTDLPELDTPESARIIAFISWLRE 1044 L++ G L LWVG + Q + + V +++ I ++ LP LD P S ++ I LR Sbjct: 982 LLENGLNLFLWVGASVQQGVVQSLFSVSSFSQITSGLSVLPVLDNPLSKKVRGLIDSLRA 1041 Query: 1045 QRPFFPILYVIRDESPMKANFLQNMIEDRTES-ALSYYEFLLHIQQQVNK 1093 QR + L V++ E M+ F ++ED++ S SY +FL H+ +++ + Sbjct: 1042 QRSRYMKLTVVKQEDKMEMLFKHFLVEDKSLSGGASYVDFLCHMHKEIRQ 1091 Score = 42.4 bits (98), Expect = 0.002 Identities = 52/171 (30%), Positives = 71/171 (41%), Gaps = 26/171 (15%) Query: 4 PGIPASG---GAPASLQAQNGAALASG--SPYTNG---PVQNA-----LLSSQESV-SQG 49 P P+SG G P SL + +G+ SG Y G P+ A + + Q S SQ Sbjct: 151 PAPPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQA 210 Query: 50 YNFQLPGSYPHPIPAKTLNPVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGP-APRM 108 +F P S +P+ T + GQS G S ++ PP A P T +GP P Sbjct: 211 SSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQM--TGPLGPLP 268 Query: 109 PLPASQNPATTPMPSSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQP 159 P+ + Q P P + SF P P N+ YP+ P SQP Sbjct: 269 PMHSPQQPGYQPQQNGSFGPARG--PQSNYGGPYPA-------APTFGSQP 310 >gi|190343021 Sec24-related protein D [Homo sapiens] Length = 1032 Score = 357 bits (917), Expect = 3e-98 Identities = 258/983 (26%), Positives = 453/983 (46%), Gaps = 95/983 (9%) Query: 192 VPPLVNPPLPTTFQPGAPH--GPPPAG--GPPPVRALTPLTSSYRDVPQPLFNSAVNQEG 247 +PP PP P F H G PP GPPPV + + Y+ Q + ++ Sbjct: 57 LPPGPPPPGPHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSS 116 Query: 248 ITSNTNNGSMVVHSSY-------DEIEGGGLLATPQLTNKNPKMSRSVGYSYPSLPPGYQ 300 +T + S + +SY + G L AT T P + LPP Sbjct: 117 VTQLGSQLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPT 176 Query: 301 NTTPPGATGVP-----PSSLNYPSGPQAFTQTP------LGANHLTTS------MSGLSL 343 PGA+ +P P L+ P P A Q P LGA + M+G L Sbjct: 177 TLNGPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQL 236 Query: 344 QPEG------LRVVNLLQERNMLPSTPLKPPVPNLHED---------------------- 375 G ++ Q + L + P+ + D Sbjct: 237 SYPGGFPGGPAQMAGPPQPQKKLDPDSIPSPIQVIENDRASRGGQVYATNTRGQIPPLVT 296 Query: 376 ----IQKL-NCNPELFRCTLTSIPQTQALLNKAKLPLGLLLHPFKDL------VQLPVVT 424 IQ N +P RCT P T + +A++PL ++ PF + + L Sbjct: 297 TDCMIQDQGNASPRFIRCTTYCFPCTSDMAKQAQIPLAAVIKPFATIPSNESPLYLVNHG 356 Query: 425 SSTIVRCRSCRTYINPFVSFLDQ-RRWKCNLCYRVNDVPEEFLYNPLTRVYG--EPHRRP 481 S VRC C+ Y+ PF+ F++ RR++C C VNDVP F + L + + + +P Sbjct: 357 ESGPVRCNRCKAYMCPFMQFIEGGRRYQCGFCNCVNDVPP-FYFQHLDHIGRRLDHYEKP 415 Query: 482 EVQNATIEFMAPSEYMLR--PPQPPVYLFVFDVSHNAVETGYLNSVCQSLLDNLDLLPGN 539 E+ + E++A +Y + PP PP ++F+ DVS++ ++ G + +C+ L L+ +P Sbjct: 416 ELSLGSYEYVATLDYCRKSKPPNPPAFIFMIDVSYSNIKNGLVKLICEELKTMLEKIPKE 475 Query: 540 TRT-----KIGFITFDSTIHFYGLQESLSQPQMLIVSDIEDVFIPMPENLLVNLNESKEL 594 + ++GFIT++ +HF+ ++ +L+QPQM++V+D+ +VF+P+ + LVN ES+ + Sbjct: 476 EQEETSAIRVGFITYNKVLHFFNVKSNLAQPQMMVVTDVGEVFVPLLDGFLVNYQESQSV 535 Query: 595 VQDLLKTLPQMFTKTLETQSALGPALQAAFKLMSPTG--GRMSVFQTQLPTLGV-GALKP 651 + +LL +P MF + E ++ P +QA + + G++ +F + LPT G LK Sbjct: 536 IHNLLDQIPDMFADSNENETVFAPVIQAGMEALKAADCPGKLFIFHSSLPTAEAPGKLKN 595 Query: 652 REEPNHRSSAKD-IHMTPSTDFYKKLALDCSGQQVAVDLFLLSGQYSDLASLGCISRYSA 710 R++ ++ K+ I P T+ Y LA DC +V LFL QY D+ASLG + + + Sbjct: 596 RDDKKLVNTDKEKILFQPQTNVYDSLAKDCVAHGCSVTLFLFPSQYVDVASLGLVPQLTG 655 Query: 711 GSVYYYPSYHHQHNPVQVQKLQKELQRYLTRKIGFEAVMRIRCTKGLSIHTFHGNFFVRS 770 G++Y Y ++ + Q+ +L+ + +KIGF+A+MR+R + G F G + + Sbjct: 656 GTLYKYNNFQMH---LDRQQFLNDLRNDIEKKIGFDAIMRVRTSTGFRATDFFGGILMNN 712 Query: 771 TDLLSLPNVNPDAGYAVQMSVEESLTDTQLVSFQSALLYTSSKGERRIRVHTLCLPVVST 830 T + + ++ D V+ ++ L++ Q A+LYT+ G+RR+R+H L L S Sbjct: 713 TTDVEMAAIDCDKAVTVEFKHDDKLSEDSGALIQCAVLYTTISGQRRLRIHNLGLNCSSQ 772 Query: 831 LNDVFLGADVQAISGLLANMAVDRSMTASLSDARDALVNAVIDSLSAYRSSVLS-NQQPG 889 L D++ + A+ A A + L R+ LVN L+ YR + S + Sbjct: 773 LADLYKSCETDALINFFAKSAFKAVLHQPLKVIREILVNQTAHMLACYRKNCASPSAASQ 832 Query: 890 LMVPFSLRLFPLFVLALLKQKSFQTGTNARLDERIFAMCQVKNQPLVYLMLTTHPSLYRV 949 L++P S+++ P+++ LLK + DER + V + L +P L + Sbjct: 833 LILPDSMKVLPVYMNCLLKNCVLLSRPEISTDERAYQRQLVMTMGVADSQLFFYPQLLPI 892 Query: 950 DNLSDEGALNISDRTIPQPPILQLSVEKLSRDGAFLMDAGSVLMLWVGKNCTQNFLSQVL 1009 L + + P ++ S +LS +G FL+ G + LW+G + + + Sbjct: 893 HTLDVKSTM--------LPAAVRCSESRLSEEGIFLLANGLHMFLWLGVSSPPELIQGIF 944 Query: 1010 GVQNYASIPQPMTDLPELDTPESARIIAFISWLREQRPFFPILYVIRDESPMKANFLQNM 1069 V ++A I MT LPE+ P S ++ + ++++RP+ L +++ + F Q + Sbjct: 945 NVPSFAHINTDMTLLPEVGNPYSQQLRMIMGIIQQKRPYSMKLTIVKQREQPEMVFRQFL 1004 Query: 1070 IEDR-TESALSYYEFLLHIQQQV 1091 +ED+ SY +FL + +++ Sbjct: 1005 VEDKGLYGGSSYVDFLCCVHKEI 1027 >gi|14591924 Sec23 homolog B [Homo sapiens] Length = 767 Score = 75.1 bits (183), Expect = 3e-13 Identities = 147/681 (21%), Positives = 255/681 (37%), Gaps = 109/681 (16%) Query: 394 PQTQALLNKAKLPLGLLLHPFKDLVQLPVVTSSTIVRCR-SCRTYINPFVSFLDQRR--W 450 P ++ + +PL LL P K+ LP V ++ R +C+ +NP +D R W Sbjct: 25 PSSRLEATRMVVPLACLLTPLKERPDLPPVQYEPVLCSRPTCKAVLNPLCQ-VDYRAKLW 83 Query: 451 KCNLCYRVNDVPEEFLYNPLTRVYGEPHRRPEVQNATIEFMAPSEYMLRPPQPP-VYLFV 509 CN C++ N P Y ++ V P Q +TIE++ + R Q P ++L+V Sbjct: 84 ACNFCFQRNQFPP--AYGGISEVNQPAELMP--QFSTIEYV-----IQRGAQSPLIFLYV 134 Query: 510 FDVSHNAVETGYLNSVCQSLLDNLDLLPGNTRTKIGFITFDSTIHFYGLQ-ESLSQPQM- 567 D +E L ++ +SL +L LLP + +G ITF + + L E +S+ + Sbjct: 135 VD---TCLEEDDLQALKESLQMSLSLLPPD--ALVGLITFGRMVQVHELSCEGISKSYVF 189 Query: 568 -----LIVSDIEDVF------IPMPE--------------NLLVNLNESKELVQDLLKTL 602 L I+D+ +PM + L +++ + DLL L Sbjct: 190 RGTKDLTAKQIQDMLGLTKPAMPMQQARPAQPQEHPFASSRFLQPVHKIDMNLTDLLGEL 249 Query: 603 ---PQMFTKTLETQSALGPALQAAFKLMS----PTGGRMSVFQTQLPTLGVGALKPREEP 655 P T+ + G AL A L+ TG R+ +F PT G G + E Sbjct: 250 QRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLFTGGPPTQGPGMVVGDELK 309 Query: 656 NHRSSAKDIH------MTPSTDFYKKLALDCSGQQVAVDLFLLSGQYSDLASLGCISRYS 709 S DI M +T Y+ LA + +D++ + + L + C + + Sbjct: 310 IPIRSWHDIEKDNARFMKKATKHYEMLANRTAANGHCIDIYACALDQTGLLEMKCCANLT 369 Query: 710 AGSVYYYPSYHHQHNPVQVQKLQKELQRYLTR------KIGFEAVMRIRCTKGLSIHTFH 763 G + S++ ++ QR T+ ++ F A + ++ ++ L I Sbjct: 370 GGYMVMGDSFN-------TSLFKQTFQRIFTKDFNGDFRMAFGATLDVKTSRELKIAGAI 422 Query: 764 G---------------NFFVRSTDLLSLPNVNPDAGYAVQMSV----EESLTDTQLVSFQ 804 G V T + ++P + + V + + Q Sbjct: 423 GPCVSLNVKGPCVSENELGVGGTSQWKICGLDPTSTLGIYFEVVNQHNTPIPQGGRGAIQ 482 Query: 805 SALLYTSSKGERRIRVHTLC---LPVVSTLNDVFLGADVQAISGLLANMAVDRSMTASLS 861 Y S +RRIRV T+ V S L + D +A + L+A + V R+ + Sbjct: 483 FVTHYQHSSTQRRIRVTTIARNWADVQSQLRHIEAAFDQEAAAVLMARLGVFRAESEEGP 542 Query: 862 DARDALVNAVIDSLSAYRSSVLSNQQPGLMVPFSLRLFPLFVLALLKQKSFQTGTNARLD 921 D L +I + + S L+P F+ L + Q N+ D Sbjct: 543 DVLRWLDRQLIRLCQKF-GQYNKEDPTSFRLSDSFSLYPQFMFHLRRSPFLQVFNNSP-D 600 Query: 922 ERIFAMCQVKNQPLVYLMLTTHPSLYRVDNLSDEGALNISDRTIPQPPILQLSVEKLSRD 981 E + Q L ++ P LY + S P+P +L S + D Sbjct: 601 ESSYYRHHFARQDLTQSLIMIQPILY-----------SYSFHGPPEPVLLDSS--SILAD 647 Query: 982 GAFLMDAGSVLMLWVGKNCTQ 1002 LMD +++++G+ Q Sbjct: 648 RILLMDTFFQIVIYLGETIAQ 668 >gi|14591926 Sec23 homolog B [Homo sapiens] Length = 767 Score = 75.1 bits (183), Expect = 3e-13 Identities = 147/681 (21%), Positives = 255/681 (37%), Gaps = 109/681 (16%) Query: 394 PQTQALLNKAKLPLGLLLHPFKDLVQLPVVTSSTIVRCR-SCRTYINPFVSFLDQRR--W 450 P ++ + +PL LL P K+ LP V ++ R +C+ +NP +D R W Sbjct: 25 PSSRLEATRMVVPLACLLTPLKERPDLPPVQYEPVLCSRPTCKAVLNPLCQ-VDYRAKLW 83 Query: 451 KCNLCYRVNDVPEEFLYNPLTRVYGEPHRRPEVQNATIEFMAPSEYMLRPPQPP-VYLFV 509 CN C++ N P Y ++ V P Q +TIE++ + R Q P ++L+V Sbjct: 84 ACNFCFQRNQFPP--AYGGISEVNQPAELMP--QFSTIEYV-----IQRGAQSPLIFLYV 134 Query: 510 FDVSHNAVETGYLNSVCQSLLDNLDLLPGNTRTKIGFITFDSTIHFYGLQ-ESLSQPQM- 567 D +E L ++ +SL +L LLP + +G ITF + + L E +S+ + Sbjct: 135 VD---TCLEEDDLQALKESLQMSLSLLPPD--ALVGLITFGRMVQVHELSCEGISKSYVF 189 Query: 568 -----LIVSDIEDVF------IPMPE--------------NLLVNLNESKELVQDLLKTL 602 L I+D+ +PM + L +++ + DLL L Sbjct: 190 RGTKDLTAKQIQDMLGLTKPAMPMQQARPAQPQEHPFASSRFLQPVHKIDMNLTDLLGEL 249 Query: 603 ---PQMFTKTLETQSALGPALQAAFKLMS----PTGGRMSVFQTQLPTLGVGALKPREEP 655 P T+ + G AL A L+ TG R+ +F PT G G + E Sbjct: 250 QRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLFTGGPPTQGPGMVVGDELK 309 Query: 656 NHRSSAKDIH------MTPSTDFYKKLALDCSGQQVAVDLFLLSGQYSDLASLGCISRYS 709 S DI M +T Y+ LA + +D++ + + L + C + + Sbjct: 310 IPIRSWHDIEKDNARFMKKATKHYEMLANRTAANGHCIDIYACALDQTGLLEMKCCANLT 369 Query: 710 AGSVYYYPSYHHQHNPVQVQKLQKELQRYLTR------KIGFEAVMRIRCTKGLSIHTFH 763 G + S++ ++ QR T+ ++ F A + ++ ++ L I Sbjct: 370 GGYMVMGDSFN-------TSLFKQTFQRIFTKDFNGDFRMAFGATLDVKTSRELKIAGAI 422 Query: 764 G---------------NFFVRSTDLLSLPNVNPDAGYAVQMSV----EESLTDTQLVSFQ 804 G V T + ++P + + V + + Q Sbjct: 423 GPCVSLNVKGPCVSENELGVGGTSQWKICGLDPTSTLGIYFEVVNQHNTPIPQGGRGAIQ 482 Query: 805 SALLYTSSKGERRIRVHTLC---LPVVSTLNDVFLGADVQAISGLLANMAVDRSMTASLS 861 Y S +RRIRV T+ V S L + D +A + L+A + V R+ + Sbjct: 483 FVTHYQHSSTQRRIRVTTIARNWADVQSQLRHIEAAFDQEAAAVLMARLGVFRAESEEGP 542 Query: 862 DARDALVNAVIDSLSAYRSSVLSNQQPGLMVPFSLRLFPLFVLALLKQKSFQTGTNARLD 921 D L +I + + S L+P F+ L + Q N+ D Sbjct: 543 DVLRWLDRQLIRLCQKF-GQYNKEDPTSFRLSDSFSLYPQFMFHLRRSPFLQVFNNSP-D 600 Query: 922 ERIFAMCQVKNQPLVYLMLTTHPSLYRVDNLSDEGALNISDRTIPQPPILQLSVEKLSRD 981 E + Q L ++ P LY + S P+P +L S + D Sbjct: 601 ESSYYRHHFARQDLTQSLIMIQPILY-----------SYSFHGPPEPVLLDSS--SILAD 647 Query: 982 GAFLMDAGSVLMLWVGKNCTQ 1002 LMD +++++G+ Q Sbjct: 648 RILLMDTFFQIVIYLGETIAQ 668 >gi|14591928 Sec23 homolog B [Homo sapiens] Length = 767 Score = 75.1 bits (183), Expect = 3e-13 Identities = 147/681 (21%), Positives = 255/681 (37%), Gaps = 109/681 (16%) Query: 394 PQTQALLNKAKLPLGLLLHPFKDLVQLPVVTSSTIVRCR-SCRTYINPFVSFLDQRR--W 450 P ++ + +PL LL P K+ LP V ++ R +C+ +NP +D R W Sbjct: 25 PSSRLEATRMVVPLACLLTPLKERPDLPPVQYEPVLCSRPTCKAVLNPLCQ-VDYRAKLW 83 Query: 451 KCNLCYRVNDVPEEFLYNPLTRVYGEPHRRPEVQNATIEFMAPSEYMLRPPQPP-VYLFV 509 CN C++ N P Y ++ V P Q +TIE++ + R Q P ++L+V Sbjct: 84 ACNFCFQRNQFPP--AYGGISEVNQPAELMP--QFSTIEYV-----IQRGAQSPLIFLYV 134 Query: 510 FDVSHNAVETGYLNSVCQSLLDNLDLLPGNTRTKIGFITFDSTIHFYGLQ-ESLSQPQM- 567 D +E L ++ +SL +L LLP + +G ITF + + L E +S+ + Sbjct: 135 VD---TCLEEDDLQALKESLQMSLSLLPPD--ALVGLITFGRMVQVHELSCEGISKSYVF 189 Query: 568 -----LIVSDIEDVF------IPMPE--------------NLLVNLNESKELVQDLLKTL 602 L I+D+ +PM + L +++ + DLL L Sbjct: 190 RGTKDLTAKQIQDMLGLTKPAMPMQQARPAQPQEHPFASSRFLQPVHKIDMNLTDLLGEL 249 Query: 603 ---PQMFTKTLETQSALGPALQAAFKLMS----PTGGRMSVFQTQLPTLGVGALKPREEP 655 P T+ + G AL A L+ TG R+ +F PT G G + E Sbjct: 250 QRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLFTGGPPTQGPGMVVGDELK 309 Query: 656 NHRSSAKDIH------MTPSTDFYKKLALDCSGQQVAVDLFLLSGQYSDLASLGCISRYS 709 S DI M +T Y+ LA + +D++ + + L + C + + Sbjct: 310 IPIRSWHDIEKDNARFMKKATKHYEMLANRTAANGHCIDIYACALDQTGLLEMKCCANLT 369 Query: 710 AGSVYYYPSYHHQHNPVQVQKLQKELQRYLTR------KIGFEAVMRIRCTKGLSIHTFH 763 G + S++ ++ QR T+ ++ F A + ++ ++ L I Sbjct: 370 GGYMVMGDSFN-------TSLFKQTFQRIFTKDFNGDFRMAFGATLDVKTSRELKIAGAI 422 Query: 764 G---------------NFFVRSTDLLSLPNVNPDAGYAVQMSV----EESLTDTQLVSFQ 804 G V T + ++P + + V + + Q Sbjct: 423 GPCVSLNVKGPCVSENELGVGGTSQWKICGLDPTSTLGIYFEVVNQHNTPIPQGGRGAIQ 482 Query: 805 SALLYTSSKGERRIRVHTLC---LPVVSTLNDVFLGADVQAISGLLANMAVDRSMTASLS 861 Y S +RRIRV T+ V S L + D +A + L+A + V R+ + Sbjct: 483 FVTHYQHSSTQRRIRVTTIARNWADVQSQLRHIEAAFDQEAAAVLMARLGVFRAESEEGP 542 Query: 862 DARDALVNAVIDSLSAYRSSVLSNQQPGLMVPFSLRLFPLFVLALLKQKSFQTGTNARLD 921 D L +I + + S L+P F+ L + Q N+ D Sbjct: 543 DVLRWLDRQLIRLCQKF-GQYNKEDPTSFRLSDSFSLYPQFMFHLRRSPFLQVFNNSP-D 600 Query: 922 ERIFAMCQVKNQPLVYLMLTTHPSLYRVDNLSDEGALNISDRTIPQPPILQLSVEKLSRD 981 E + Q L ++ P LY + S P+P +L S + D Sbjct: 601 ESSYYRHHFARQDLTQSLIMIQPILY-----------SYSFHGPPEPVLLDSS--SILAD 647 Query: 982 GAFLMDAGSVLMLWVGKNCTQ 1002 LMD +++++G+ Q Sbjct: 648 RILLMDTFFQIVIYLGETIAQ 668 >gi|38202214 SEC23-related protein A [Homo sapiens] Length = 765 Score = 67.0 bits (162), Expect = 9e-11 Identities = 143/679 (21%), Positives = 253/679 (37%), Gaps = 107/679 (15%) Query: 394 PQTQALLNKAKLPLGLLLHPFKDLVQLPVVTSSTIVRCRS-CRTYINPFVSFLDQRR--W 450 P ++ + +P+ L P K+ LP + ++ R+ CR +NP +D R W Sbjct: 25 PSSRLEATRMVVPVAALFTPLKERPDLPPIQYEPVLCSRTTCRAVLNPLCQ-VDYRAKLW 83 Query: 451 KCNLCYRVNDVPEEFLYNPLTRVYGEPHRRPEVQNATIEFMAPSEYMLRPPQPP-VYLFV 509 CN CY+ N P Y ++ + P Q ++IE++ +LR PQ P ++L+V Sbjct: 84 ACNFCYQRNQFPPS--YAGISELNQPAELLP--QFSSIEYV-----VLRGPQMPLIFLYV 134 Query: 510 FDVSHNAVETGYLNSVCQSLLDNLDLLPGNTRTKIGFITFDSTIHFYGLQ-ESLSQ---- 564 D +E L ++ +S+ +L LLP +G ITF + + L E +S+ Sbjct: 135 VD---TCMEDEDLQALKESMQMSLSLLP--PTALVGLITFGRMVQVHELGCEGISKSYVF 189 Query: 565 -----------PQMLIVSDI--------EDVFIPMPENLLVNLNESKEL-VQDLLKTL-- 602 +ML +S + V P P N + + ++ + DLL L Sbjct: 190 RGTKDLSAKQLQEMLGLSKVPLTQATRGPQVQQPPPSNRFLQPVQKIDMNLTDLLGELQR 249 Query: 603 -PQMFTKTLETQSALGPALQAAFKLMS----PTGGRMSVFQTQLPTLGVGALKPREEPNH 657 P + + G AL A L+ TG R+ +F T G G + E Sbjct: 250 DPWPVPQGKRPLRSSGVALSIAVGLLECTFPNTGARIMMFIGGPATQGPGMVVGDELKTP 309 Query: 658 RSSAKDI------HMTPSTDFYKKLALDCSGQQVAVDLFLLSGQYSDLASLGCISRYSAG 711 S DI ++ T ++ LA + +D++ + + L + C + G Sbjct: 310 IRSWHDIDKDNAKYVKKGTKHFEALANRAATTGHVIDIYACALDQTGLLEMKCCPNLTGG 369 Query: 712 SVYYYPSYHHQHNPVQVQKLQKELQRYLTR------KIGFEAVMRIRCTKGLSIHTFHG- 764 + S++ ++ QR T+ K+GF + I+ ++ + I G Sbjct: 370 YMVMGDSFN-------TSLFKQTFQRVFTKDMHGQFKMGFGGTLEIKTSREIKISGAIGP 422 Query: 765 --------------NFFVRSTDLLSLPNVNPDAGYAVQMSV----EESLTDTQLVSFQSA 806 T + ++P A+ V + + Q Sbjct: 423 CVSLNSKGPCVSENEIGTGGTCQWKICGLSPTTTLAIYFEVVNQHNAPIPQGGRGAIQFV 482 Query: 807 LLYTSSKGERRIRVHTLC---LPVVSTLNDVFLGADVQAISGLLANMAVDRSMTASLSDA 863 Y S G+RRIRV T+ + + ++ D +A + L+A +A+ R+ T D Sbjct: 483 TQYQHSSGQRRIRVTTIARNWADAQTQIQNIAASFDQEAAAILMARLAIYRAETEEGPDV 542 Query: 864 RDALVNAVIDSLSAYRSSVLSNQQPGLMVPFSLRLFPLFVLALLKQKSFQTGTNARLDER 923 L +I + + + L+P F+ L++ SF N DE Sbjct: 543 LRWLDRQLIRLCQKF-GEYHKDDPSSFRFSETFSLYPQFMFH-LRRSSFLQVFNNSPDES 600 Query: 924 IFAMCQVKNQPLVYLMLTTHPSLYRVDNLSDEGALNISDRTIPQPPILQLSVEKLSRDGA 983 + Q L ++ P LY A + S P P+L L + D Sbjct: 601 SYYRHHFMRQDLTQSLIMIQPILY---------AYSFSG---PPEPVL-LDSSSILADRI 647 Query: 984 FLMDAGSVLMLWVGKNCTQ 1002 LMD ++++ G+ Q Sbjct: 648 LLMDTFFQILIYHGETIAQ 666 >gi|54860079 nadrin isoform 1 [Homo sapiens] Length = 881 Score = 65.5 bits (158), Expect = 3e-10 Identities = 76/266 (28%), Positives = 98/266 (36%), Gaps = 30/266 (11%) Query: 3 QPGIPASGGAPASLQAQNGAALASGSPYTNGPVQNALLSSQESVSQGYNFQLPGSY---- 58 +P P S PA +N + +ASG N P Q A S Q S+ Q +N P + Sbjct: 578 KPKDPVSAAVPAP--GRNNSQIASGQ---NQP-QAAAGSHQLSMGQPHNAAGPSPHTLRR 631 Query: 59 ----PHPIPAKTLNPVSGQSNYGGSQGSGQ---TLNRPPVASNPVTPSLHSGPAPRMPLP 111 P P P K NP G S G+ Q +L+ P +P P+ H+G P P Sbjct: 632 AVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSA 691 Query: 112 ASQNPATTPMPSSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNH 171 SQ + P SS L P N+P T P ++P G + Sbjct: 692 PSQ--LSAPRRYSSSLSPIQAP-------NHPPPQPPTQATPLMHTKPNSQGPPNPMALP 742 Query: 172 QYVSSGYPSLQNSFIKSGPSVPPL--VNP--PLPTTFQPGAPHGPPPAGGPPPVRALTPL 227 PS + PS PPL NP P P T G P P G P P Sbjct: 743 SEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRPRPVPK 802 Query: 228 TSSYRDVPQPLFNSAVNQEGITSNTN 253 + VP P V+ G +S TN Sbjct: 803 PRNRPSVPPPPQPPGVHSAGDSSLTN 828 >gi|54860105 nadrin isoform 2 [Homo sapiens] Length = 803 Score = 65.5 bits (158), Expect = 3e-10 Identities = 76/266 (28%), Positives = 98/266 (36%), Gaps = 30/266 (11%) Query: 3 QPGIPASGGAPASLQAQNGAALASGSPYTNGPVQNALLSSQESVSQGYNFQLPGSY---- 58 +P P S PA +N + +ASG N P Q A S Q S+ Q +N P + Sbjct: 500 KPKDPVSAAVPAP--GRNNSQIASGQ---NQP-QAAAGSHQLSMGQPHNAAGPSPHTLRR 553 Query: 59 ----PHPIPAKTLNPVSGQSNYGGSQGSGQ---TLNRPPVASNPVTPSLHSGPAPRMPLP 111 P P P K NP G S G+ Q +L+ P +P P+ H+G P P Sbjct: 554 AVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSA 613 Query: 112 ASQNPATTPMPSSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNH 171 SQ + P SS L P N+P T P ++P G + Sbjct: 614 PSQ--LSAPRRYSSSLSPIQAP-------NHPPPQPPTQATPLMHTKPNSQGPPNPMALP 664 Query: 172 QYVSSGYPSLQNSFIKSGPSVPPL--VNP--PLPTTFQPGAPHGPPPAGGPPPVRALTPL 227 PS + PS PPL NP P P T G P P G P P Sbjct: 665 SEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRPRPVPK 724 Query: 228 TSSYRDVPQPLFNSAVNQEGITSNTN 253 + VP P V+ G +S TN Sbjct: 725 PRNRPSVPPPPQPPGVHSAGDSSLTN 750 >gi|150417989 cyclin K isoform 1 [Homo sapiens] Length = 580 Score = 62.0 bits (149), Expect = 3e-09 Identities = 53/163 (32%), Positives = 70/163 (42%), Gaps = 24/163 (14%) Query: 93 SNPVTPSLHSGPAPRMPLPASQNPATTPMP-SSSFLPEANLPPPLNWQYNYPSTASQTNH 151 ++P P H P + PL A+ A P P ++ LP+ +PPP +P+ Q Sbjct: 361 THPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPA-----HPAPVHQPPP 415 Query: 152 CP-RASSQPTVSGNTSLTTNHQYVSS-GYPSLQNSFIKSGPS---VPPLVNPPLPTTFQP 206 P R P S T ++T Y+S GY SLQ+ GPS +PP PP P Sbjct: 416 LPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPP---AHLP 472 Query: 207 GAPHGPPPAGGPPPV---------RALTPLTSSYRDVPQPLFN 240 PH PP PPPV A+ P T Y P P +N Sbjct: 473 YHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGY-PPPPPTYN 514 Score = 42.4 bits (98), Expect = 0.002 Identities = 50/172 (29%), Positives = 63/172 (36%), Gaps = 24/172 (13%) Query: 54 LPGSYPHPIPAKTLNPVSGQSNYGGSQG--SGQTLNRPPVASNPVTPSLHSGPA--PRMP 109 LP P P P+ + +S S+Y +G S Q++ + S P + PA P P Sbjct: 416 LPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHP 475 Query: 110 --LPASQNPATTPMPSSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSL 167 P + P P P +SF P A +PPP YP N P P T Sbjct: 476 HVYPPNPPPPPVPPPPASFPPPA-IPPPTP---GYPPPPPTYN--PNFPPPPPRLPPTHA 529 Query: 168 TTNHQYVSSGYPSLQNSFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGGPP 219 H G P S PP P +P QP P PP G PP Sbjct: 530 VPPHPPPGLGLPPA---------SYPP---PAVPPGGQPPVPPPIPPPGMPP 569 Score = 39.3 bits (90), Expect = 0.021 Identities = 76/348 (21%), Positives = 106/348 (30%), Gaps = 65/348 (18%) Query: 62 IPAKTLNPVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAPRMPLPASQNPATTPM 121 +P L + Q SQG Q + P PSL P P++P P+ + Sbjct: 242 VPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQ-PPSLQ--PTPQVPQVQQSQPSQSSE 298 Query: 122 PSSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSGYPSL 181 PS + P P S PR + V + P + Sbjct: 299 PSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKI 358 Query: 182 QNSFIKSGPSVPPLVN-PPLPTTFQPGAPHGP-----------PPAGGPPPVRALTPLTS 229 + + P+ PP PPL P GP PP P PV PL Sbjct: 359 ETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLP- 417 Query: 230 SYRDVPQPLFNSAVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQLTNKNPKMSRSVG 289 +R P P ++ M SSY EG L + M ++ G Sbjct: 418 -HRPPPPP------------PSSYMTGMSTTSSYMSGEGYQSLQS---------MMKTEG 455 Query: 290 YSYPSLPPGY--------------QNTTPPGA---------TGVPPSSLNYPSGPQAFTQ 326 SY +LPP Y N PP +PP + YP P + Sbjct: 456 PSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNP 515 Query: 327 T-PLGANHLTTSMSGLSLQPEGLRVVNLLQERNMLP---STPLKPPVP 370 P L + + P GL + +P P+ PP+P Sbjct: 516 NFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIP 563 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 62.0 bits (149), Expect = 3e-09 Identities = 91/347 (26%), Positives = 125/347 (36%), Gaps = 71/347 (20%) Query: 4 PGIPASGGAPASLQAQNGAALASGSPYTNGPVQNALLSSQESVSQGYNFQLPGSYPHPIP 63 P PA APA + A +P G +P S P P Sbjct: 900 PATPAPKQAPALSMTSSSPKKARATPAPKG--------------------IPAS-PSPKG 938 Query: 64 AKTLNPVSGQSNYGG-SQGSGQTLNRPPVAS------NPVTPSLHSGPAPRMPLPAS-QN 115 A T + S GG + S + PP A+ P TPS P P P S + Sbjct: 939 APTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKG 998 Query: 116 PATTPMPSSSFLPEANLPPPLNWQ---YNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQ 172 TP P + P A PP +P AS P A++ P+ G+ + T Sbjct: 999 GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAST----PPAATPPSPKGSPAATP--- 1051 Query: 173 YVSSGYPSLQNSFI---KSGPSVPPLVNPPLPTTFQPGAPHG----PPPAGGPPPVRALT 225 + G P+ + + K GP+ P L P P P +P G P P G P P A T Sbjct: 1052 -LPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMP-PAAT 1109 Query: 226 PLTSSYRDVPQPLFNSAVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQLTNKNPKMS 285 P P P + G+ + + G+ ++ GGL P PK + Sbjct: 1110 P--------PSP-------KGGLATPPHKGAPTTPAATPPSPKGGLATPP------PKGA 1148 Query: 286 RSVGYSYPSLPPGYQNTTPP-GATGVPPSSLNYPSGPQAFTQTPLGA 331 + + P P G T PP GA P ++ P G A T +P GA Sbjct: 1149 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA-TPSPKGA 1194 Score = 50.1 bits (118), Expect = 1e-05 Identities = 64/260 (24%), Positives = 80/260 (30%), Gaps = 29/260 (11%) Query: 89 PPVASNPVTPSLHSGPAPRMPLPASQNPATTPMPSSSFLPEANLPPPLNWQYNYPSTASQ 148 P +P PS P P P S T P + NLP P P+T Sbjct: 850 PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEG----PAT--- 902 Query: 149 TNHCPRASSQPTVSGNTSLTTNHQYVSSGYPSLQNSFIKSGPSVPPLVNPPLPTTFQPGA 208 P P +S TS + + + S G PP PP P G Sbjct: 903 ----PAPKQAPALS-MTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSP----KGG 953 Query: 209 PHGPPPAGGPPPVRALTPLTSSYRDVPQPLFNSAVNQEGITSNTNNGSMVVHSSYDEIEG 268 P P P P P A P P P A T + G S Sbjct: 954 PATPSPKWAPTPPAATPPSPKGGPATPSP--KGAPTPPAATPPSPKGGPATPSP------ 1005 Query: 269 GGLLATPQLTNKNPKMSRSVGYSYP---SLPPGYQNTTPPGATGVPPSSLNYPSGPQAFT 325 G P +T +PK S +P S PP +P G+ P P+ P A Sbjct: 1006 KGAPTPPAVTPPSPKGS-PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATL 1064 Query: 326 QTPLGANHLTTSMSGLSLQP 345 +P G T S+ G P Sbjct: 1065 PSPKG-GPATPSLKGAPTPP 1083 Score = 47.8 bits (112), Expect = 6e-05 Identities = 77/291 (26%), Positives = 98/291 (33%), Gaps = 53/291 (18%) Query: 59 PHPIPAKTLNPVSGQSNYGGSQGSGQT-----LNRPPVASNPVTPSLHSGPAPRM----P 109 P P A T + V+ S G + +T +N P P TP+ PA M P Sbjct: 859 PSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSP 918 Query: 110 LPASQNPA-----TTPMPSSSFLPEANLPPPLNWQYNYPSTAS-QTNHCPRASSQPTVSG 163 A PA +P P + P A PP P+T S + P A++ P+ G Sbjct: 919 KKARATPAPKGIPASPSPKGAPTPPAATPPS---PKGGPATPSPKWAPTPPAATPPSPKG 975 Query: 164 NTSLTTNHQYVSSGYPSLQNSFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGGPPPVRA 223 + + G PP PP P G P P P G P P A Sbjct: 976 GPATPS-----------------PKGAPTPPAATPPSP----KGGPATPSPKGAPTP-PA 1013 Query: 224 LTPLTSSYRDVPQPLFNSAVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQLTNKNPK 283 +TP + P A T + GS G TP T +PK Sbjct: 1014 VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL-----PKGAPTTPAATLPSPK 1068 Query: 284 MSRSVGYSYPSL--PPGYQNTTPPGATGVP--PSSLNYPSGPQAFTQTPLG 330 G + PSL P TPP G P PS P P A +P G Sbjct: 1069 ----GGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKG 1115 Score = 47.0 bits (110), Expect = 1e-04 Identities = 72/327 (22%), Positives = 102/327 (31%), Gaps = 23/327 (7%) Query: 59 PHPIPAKTLNPVSGQSNYGG-SQGSGQTLNRPPVASNP------VTPSLHSGPA-PRMPL 110 P P A T + S GG + S + P A+ P TPS P P Sbjct: 1189 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1248 Query: 111 PASQNPATTPMPSSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTN 170 P+ + TP P + P A PP L P N P + P+ G + T+ Sbjct: 1249 PSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPN--PAVVTPPSPKGGPA--TS 1304 Query: 171 HQYVSSGYPSLQNSFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGGPPPVRALTPLTSS 230 + P+ K P PP P P P +P G P P P T S Sbjct: 1305 PPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPS 1364 Query: 231 YRDVPQPLFNSAVNQEG---ITSNTNNGSMVVHSSYDEIEGGGLLATPQLTNKNPKMSRS 287 ++ P P + ++ G + G + D + +P+ P Sbjct: 1365 SKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREG 1424 Query: 288 VGYSYPSLPPGYQNTTPPGATGVPPSSLNYPSGPQAFTQTP--LGANHLTTSMSGLSLQP 345 + P + TPP T V S P+ TP G L +P Sbjct: 1425 ------AATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEP 1478 Query: 346 EGLRVVNLLQERNMLPSTPLKPPVPNL 372 + V P+TP P L Sbjct: 1479 PAPKQVATSSSPKKAPATPAPMGAPTL 1505 Score = 44.7 bits (104), Expect = 5e-04 Identities = 74/320 (23%), Positives = 106/320 (33%), Gaps = 42/320 (13%) Query: 95 PVTPSLHSGP-APRMPLPASQNPATTPMPSSSFLPEANLPPPLNWQ-YNYPSTASQTNHC 152 P TPS P AP L + + PAT + P +P P P A T Sbjct: 1517 PATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSS 1576 Query: 153 PRASSQPTVSGNTSLTTNHQYVSSGYPSLQNSFIKSGPSVPPLVNPPLPTTFQPGAPHGP 212 ASS P V+ +T G PS + I + P P P P +P Sbjct: 1577 KEASSPPAVTPSTY---------KGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKG 1627 Query: 213 PPAGGPPPVRALTPLT-SSYRDVPQPLFNSAVNQEGITSNTNNG--SMVVHSSYDEI--- 266 P P P+T SS +D P + + G + ++ E+ Sbjct: 1628 PATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVA 1687 Query: 267 ---EGGGLLATPQLTNKNPKMSRSVGYSYPSLP-PGYQNTTPPGATGVPPSSL------- 315 E ++ P T K P+ +S S P P P +N + + V P+ L Sbjct: 1688 PAPESTPIITAP--TRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDS 1745 Query: 316 ----------NYPSGPQAFTQTPLGANHLTTSMSGLSLQPEGLRVVNLLQERNMLPSTPL 365 + P GP A ++ + + +PE V LP P Sbjct: 1746 SKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAP- 1804 Query: 366 KPPVPNLHEDIQKLNCNPEL 385 PVP L Q L +P L Sbjct: 1805 -SPVPTLPPKQQFLPSSPGL 1823 Score = 38.9 bits (89), Expect = 0.027 Identities = 83/376 (22%), Positives = 139/376 (36%), Gaps = 54/376 (14%) Query: 19 QNGAALASGSPYTNGPVQNALLSSQESVSQGYNFQLPGS-YPHPIPAKTLNPVSGQSNYG 77 +N + S S P+ +++S+ + P S P+ + V +Y Sbjct: 568 KNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYA 627 Query: 78 GSQGSGQTLNR----PPVASNPVTPSLHSGPAPRMPLPASQNPATTPMPSSSFLP-EANL 132 G +G L P VA+ P+ + +G AP ++ +T +S FL +L Sbjct: 628 GPDSAGPLLKSSLITPTVAAFPLESADPAGVAPT----TAKGTSTYTTTASPFLEGTVSL 683 Query: 133 PPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSGYPSLQNSFIKSGPSV 192 P N+P P PT S N + + Q + +L + P + Sbjct: 684 APK-----NHPVKEGTLTTLPLV---PTASENCPVAPSPQNTCAPLATLVLA-----PEI 730 Query: 193 PPLVNPPLPTTFQPGAPHGPPPAGGPPPVRALTPLTSSYRDVPQPLFNSAVNQEGITSNT 252 P V P P+ G P G G AL P+ SS ++ P G ++ Sbjct: 731 PKSV--PSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECP-------TEDSGASATA 781 Query: 253 NNGSMVVHSSYDEIEGGGLLATPQLTNKNPKMSRSVGYSYPSLPPGYQNT--TPPGATGV 310 ++ + + + D G+ +PQ T + P S G P P G ++ +P A+ + Sbjct: 782 SSKGTLTYLA-DSPSPLGVSVSPQ-TKRPPTKKGSAG---PDTPIGNLSSPVSPVEASFL 836 Query: 311 PPSSLNY----PSGPQAFTQTPLGANHLTTSMSGLSLQPEGL----------RVVNLLQE 356 P +SL++ S + TP T + L P+G+ VVNL Sbjct: 837 PENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFP 896 Query: 357 RNMLPSTPLKPPVPNL 372 + P+TP P L Sbjct: 897 KEG-PATPAPKQAPAL 911 Score = 34.3 bits (77), Expect = 0.66 Identities = 43/182 (23%), Positives = 67/182 (36%), Gaps = 11/182 (6%) Query: 63 PAKTLNPVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGP----APRMPLPASQNPAT 118 PA P+ G Q + PP+ +P + GP AP LP ++ + Sbjct: 1688 PAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSK 1747 Query: 119 TPM-PSSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSG 177 T +S P+ L PP + + + P TA+ +VS S + S Sbjct: 1748 TAKGKDASHSPKGPLAPPES-KASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSP 1806 Query: 178 YPSL--QNSFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGGPPPVRALTPLTSSYRDVP 235 P+L + F+ S P + L +P P P P P P+ P S ++P Sbjct: 1807 VPTLPPKQQFLPSSPGL-VLESPSKP--LAPADEDELLPLIPPEPISGGVPFQSVLVNMP 1863 Query: 236 QP 237 P Sbjct: 1864 TP 1865 Score = 33.5 bits (75), Expect = 1.1 Identities = 94/447 (21%), Positives = 155/447 (34%), Gaps = 89/447 (19%) Query: 80 QGSGQTLNRPPVASNPVTPSLHSGPAPRMPLPASQNP---------ATTPMPSSSFLPEA 130 Q +T P ++ VT +L P P +P P S P +P PS S + A Sbjct: 18 QPQAETAVLPMSSALSVTAALGQ-PGPTLPPPCSPAPQQCPLSAANQASPFPSPSTI--A 74 Query: 131 NLPPPLNWQYNYPSTASQTNHCPRASS----------------------QPTVSGNTSLT 168 + P + + + TA P A + PT+ G S + Sbjct: 75 STPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSS 134 Query: 169 TNHQYVSSGYPSLQNS------FIKSGPSVPPLVNPPLPTTFQPGAPHGPP--------- 213 V+ S+Q S + S PSV + + T P AP P Sbjct: 135 APLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSE 194 Query: 214 ----PAGGPPP-----------VRALTPLTSSYRDVPQ--PLFNSAVNQEGITSNTNNGS 256 P G P P V + + S +PQ P A+ + T + Sbjct: 195 VVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSV 254 Query: 257 MVVHSSYDEIEGGGLLATPQL----TNKNPKMSRSVGYSYPSLPPGY-----QNTTPPGA 307 ++ + + G ++ P T P ++ S + P+ PP + + P Sbjct: 255 LISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQ 314 Query: 308 TGVPPSSLNYPSGPQAFTQTPLGANHLTTSMSGLSLQPEGLRVVNLLQERN-MLPST--- 363 + L +GP A + + + S +G S P V+ L RN ++P+T Sbjct: 315 SSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGAS-YPSQRSVIPPLPSRNEVVPATVAA 373 Query: 364 --PLKPPVPNLHEDIQKLNCNP--ELFRCTLTSIPQTQALLNKAKLPLGLLLHPFKDLVQ 419 + P V I + C+P L T S+ T +L+ K+ P +P + Q Sbjct: 374 FPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSS-PNATYHYPL--VAQ 430 Query: 420 LPV--VTSSTIVRCRSCRTYINPFVSF 444 +PV V ++ +V C P +F Sbjct: 431 MPVSSVGTTPLVVTNPCTIAAAPTTTF 457 Score = 33.1 bits (74), Expect = 1.5 Identities = 85/376 (22%), Positives = 129/376 (34%), Gaps = 64/376 (17%) Query: 4 PGIPASGGAPASLQAQNGAALASGSPYTNGPVQNALLSSQESVSQGYNF--QLPGSYPHP 61 P + +S+ +L + ++ P + +L S + + Y Q+P S Sbjct: 379 PSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGT 438 Query: 62 IPAKTLNPVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGP-----APRMPL-PASQN 115 P NP + + + T PP++S P++ + P AP P P++Q Sbjct: 439 TPLVVTNPCTIAAA-PTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQV 497 Query: 116 PATTPMPSSSFLPE----ANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNH 171 T +P S LP+ NLP + +P+ P LTT Sbjct: 498 ATTLRIPVSPPLPDPEDLKNLPSSV--LVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKK 555 Query: 172 --------QYVSSGYPSLQNSFIKSGPSVP--PLVNPPLPTTFQPGAPHGPPPAGGPPPV 221 Q PS Q++ S P +P P + +P P G P + P+ Sbjct: 556 DPTVLPLVQAAPKNSPSFQST--SSSPEIPLSPEATLAKKSLGEP-LPIGKPASSMTSPL 612 Query: 222 ----RALTPLTSSYR--DVPQPLFNSAV-------------NQEGITSNTNNGSMVVHSS 262 A T SY D PL S++ + G+ T G+ S+ Sbjct: 613 GVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGT----ST 668 Query: 263 YDEIEGGGLLATPQLTNKNPKMSRSVGYSYPSLP---------PGYQNTTPPGATGV--- 310 Y L T L KN + + P +P P QNT P AT V Sbjct: 669 YTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAP 728 Query: 311 -PPSSLNYPSGPQAFT 325 P S+ PS P A T Sbjct: 729 EIPKSVPSPSLPPAGT 744 Score = 32.7 bits (73), Expect = 1.9 Identities = 87/347 (25%), Positives = 118/347 (34%), Gaps = 54/347 (15%) Query: 22 AALASGSPYTNGPVQNALLSSQESVSQGYNFQLPGSYPHPIPAKTLNP----VSGQSNYG 77 AALA SP P SS ++ L PH + + P S S Sbjct: 114 AALALASPMI-APTLKGTPSSSAPLA------LVALAPHSVQKSSAFPPNLLTSPPSVAV 166 Query: 78 GSQGSGQTLNRPPVASNPVTPSLHSGPAPRMPLPASQNPATTPMPSS--SFLPEANLPPP 135 GS TL+ P S P T +L+ P+ +P NP TP P S +P + P Sbjct: 167 AESGSVITLSAPIAPSEPKT-NLNKVPSEVVP-----NPKGTPSPPCIVSTVPYHCVTPM 220 Query: 136 LNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSGYPSLQN--SFIKSGPSVP 193 + Q S T A + P V T +SS S QN S GP P Sbjct: 221 ASIQSGVASLPQTTPTTTLAIASPQVKDTT--------ISSVLISPQNPGSLSLKGPVSP 272 Query: 194 PLV------NPPLPTTFQPGAPHGPPPAGGPPPVRALTPLTSSYRDVPQPLFNSAVNQEG 247 P + P+ T+ Q A PP L PL S Q L Sbjct: 273 PAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLL--GQTGPSA 330 Query: 248 ITSNTNNGSMVVHSSYDEIEGGGLLATPQLTNKNPKMSRSVGYSYPSLPPGYQ------- 300 ++ T V HSS P L ++N + +V ++P + P Sbjct: 331 LSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVA-AFPVVAPSVDKGPSTIS 389 Query: 301 --NTTPPGATGV-------PPSSLNYPSGPQAFTQTPLGANHLTTSM 338 +P G+ V P +SL S P A PL A +S+ Sbjct: 390 SITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSV 436 Score = 32.0 bits (71), Expect = 3.3 Identities = 69/304 (22%), Positives = 98/304 (32%), Gaps = 33/304 (10%) Query: 89 PPVASNPVTPSLHSGPAPRMPLPASQNPATTPMP-SSSFLPEANLPPPLNWQYNYPSTAS 147 P P P+ PA AS PA TP + P+ L PP T+ Sbjct: 1556 PSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPP-------AVTSP 1608 Query: 148 QTNHCPRASSQPTVSGNTSLTTNHQYVSSGYPSLQNSFIKSGPSVPPLVNPPLPTTFQPG 207 P + S T + P + S +K P+ P V + T P Sbjct: 1609 SPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATV-PQ 1667 Query: 208 APHGPPPAGGP--------PPVRALTP-LTSSYRDVPQPLFNSAVNQEGITS-NTNNGSM 257 A G P GP P TP +T+ R PQ +SA + + NGS Sbjct: 1668 ASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGS- 1726 Query: 258 VVHSSYDEIEGGGLLATPQLTNKNPK-MSRSVGYSYPSLPPGYQNTTPPGATGV-----P 311 + LL + ++K K S P PP + +TP A Sbjct: 1727 --KGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPK 1784 Query: 312 PSSLNYPSGPQAFTQTPLGANHLTTSMSGLSLQPEGLRVVNLLQERNMLPS-----TPLK 366 P S + + P PL + + T P +V + + P+ PL Sbjct: 1785 PESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLI 1844 Query: 367 PPVP 370 PP P Sbjct: 1845 PPEP 1848 >gi|151301154 mucin 6, gastric [Homo sapiens] Length = 2439 Score = 59.7 bits (143), Expect = 1e-08 Identities = 74/332 (22%), Positives = 117/332 (35%), Gaps = 48/332 (14%) Query: 13 PASLQAQNGAALASGSPYTNGPVQN-----------ALLSSQESVSQGYNFQLPGSY--- 58 P QA A ++ SP T Q+ A + ++ + N +LPG+ Sbjct: 1299 PTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQ 1358 Query: 59 ---PHPIPAKTLNPVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAPRMPLPASQN 115 P P PA T P + Q + +T + H+ +P P S Sbjct: 1359 TTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSP--PTAGSPV 1416 Query: 116 PATTPMPSSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVS 175 P+T P+ ++SF P P ++P T T+ P ++S T S +T +T H ++ Sbjct: 1417 PSTGPVTATSFHATTTYPTP-----SHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMA 1471 Query: 176 SGYPSLQNSFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGGPPPVRALTPLTSSYRDVP 235 + S S P PP T G+ H PP +TP TS Sbjct: 1472 TS---------ASNHSAPTGTIPPPTTLKATGSTHTAPP---------ITPTTSG----T 1509 Query: 236 QPLFNSAVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQLTNKNPKMSRSVGYSYPSL 295 +S + TS ++ S H + P T ++ + + Sbjct: 1510 SQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRP 1569 Query: 296 PPGYQNTTPPGATGVPPSSLNYPSGPQAFTQT 327 PP + +PP TG P S P +F T Sbjct: 1570 PPPFTTHSPP--TGSSPFSSTGPMTATSFKTT 1599 Score = 46.2 bits (108), Expect = 2e-04 Identities = 77/327 (23%), Positives = 124/327 (37%), Gaps = 40/327 (12%) Query: 25 ASGSPYTNGPVQNALLSSQESVSQGYNFQLPGSYPHPIPAKTLNP-VSGQSNYGGSQGSG 83 A+GS +T P+ + ++ S + P S H + T +P V+ S + Sbjct: 1492 ATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSL-HSHTSSTHHPEVTPTSTTTITPNPT 1550 Query: 84 QTLNRPPVA-SNPVTPSLHSGPAPRMPLPASQNP--ATTPMPSSSFLPEANLPPPLNWQY 140 T R PVA +N T S P P +P +T PM ++SF P P Sbjct: 1551 STRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTP----- 1605 Query: 141 NYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSGYPSLQNSFIKSGPSVPPLVNPPL 200 ++P T T+ P ++S T S +T +T H +++ S S+P PP Sbjct: 1606 SHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATS---------ASIHSMPTGTIPPP 1656 Query: 201 PTTFQPGAPHGPPPAGGPPPVRALTPLTSSYRDVPQPLFNSAVNQEGI---TSNTNNGSM 257 T G+ H P LT+S N+A + TS+T++ Sbjct: 1657 TTLKATGSTHTAP----------TMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEA 1706 Query: 258 VVHSSYDEIEGGGLLATPQLT-----NKNPKMSRSVGYSYPSLPPGYQNTTPPGATGVPP 312 S+ + TP +T + S S + SL +T P T Sbjct: 1707 TSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTST 1766 Query: 313 SSLNYPSGPQAFTQTPLGANHLTTSMS 339 +S+ P+ T+TP+ H T++ S Sbjct: 1767 TSIT-PNHTSTGTRTPVA--HTTSATS 1790 Score = 46.2 bits (108), Expect = 2e-04 Identities = 60/221 (27%), Positives = 92/221 (41%), Gaps = 30/221 (13%) Query: 69 PVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAPRMPLPAS-QNPATTPMPSSSFL 127 PV + GS S T P AS +P S PA + A+ + ++P S+ L Sbjct: 2169 PVHSTTLSSGSHSSLST--HPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALL 2226 Query: 128 PEANL---PPPLNWQYNY-------PSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSG 177 P + + P P + + P T + T+ P SSQ T S +TSLTT + +SG Sbjct: 2227 PISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTT--RVPTSG 2284 Query: 178 YPSLQNSFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGGPPPVRALTPLTSSYRDVPQP 237 + SL + +G P+ N TT PG P R LT +++ P Sbjct: 2285 FVSLTSGV--TGIPTSPVTN---LTTRHPGPTLS-------PTTRFLTSSLTAHGSTPA- 2331 Query: 238 LFNSAVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQLT 278 ++ V+ G + T+ G V +EI G +A +T Sbjct: 2332 --SAPVSSLGTPTPTSPGVCSVREQQEEITFKGCMANVTVT 2370 Score = 43.5 bits (101), Expect = 0.001 Identities = 81/354 (22%), Positives = 123/354 (34%), Gaps = 50/354 (14%) Query: 25 ASGSPYTNGPVQNALLSSQESVSQGYNFQLPGSYPHPIPAKTLNPVSGQSNYGGSQGSGQ 84 A+GS +T P+ + +S S + S P+ + V+ S + Sbjct: 1885 ATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTS 1944 Query: 85 TLNRPPVASN--------PVTPSLHSGPAPRMPLPASQNPATTPMPSSSFLPEANLPPPL 136 T R PVA P + HS P P + T PM ++SF P P Sbjct: 1945 TGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSS-----TGPMTATSFQTTTTYPTP- 1998 Query: 137 NWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSGYPSLQNSFIKSGPSVPPLV 196 ++P T T+ P ++S T S +T + T H +++ S S P Sbjct: 1999 ----SHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATS---------ASIHSTPTGT 2045 Query: 197 NPPLPTTFQPGAPHGPPPAGGPPPVRALTPLTSSYRDVPQPLFNSAVNQEGITSNT---N 253 PP T G+ H PP +T TS + + I+S++ Sbjct: 2046 VPPPTTLKATGSTHTAPP---------MTVTTSGTSQTHSSFSTATASSSFISSSSWLPQ 2096 Query: 254 NGSMVVHSS--YDEIEGGGLLATPQLTNKNPKMSRSVGYSYPSLPPGYQNTTPPGATGVP 311 N S SS ++ TP T S S S PS Y P + P Sbjct: 2097 NSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSY----VPSSHSSP 2152 Query: 312 PSSLNYPSGPQAFTQTPLGANHLTT-SMSGLSLQPEGLRVVNLLQERNMLPSTP 364 +S +F P+ + L++ S S LS P V + PS+P Sbjct: 2153 QTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASV----SASPLFPSSP 2202 Score = 37.7 bits (86), Expect = 0.060 Identities = 56/229 (24%), Positives = 73/229 (31%), Gaps = 47/229 (20%) Query: 53 QLPGSYPHPIPAKTLNPVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAPRMPLPA 112 QLP + P + S S G + N P AS TP L + P + Sbjct: 1209 QLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTP-ASPTQTPLLPATLTSSKPTAS 1267 Query: 113 SQNP-----ATTPMPSSSFLPEANL----PPPLNWQYNYPSTASQTNHCPRASSQPTVSG 163 S P A TP +S P A L P Q +TAS + +++Q T Sbjct: 1268 SGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQSTT-- 1325 Query: 164 NTSLTTNHQYVSSGYPSLQNSFIKSGPSV---------PPLVNPPLPTTFQPGAP----- 209 T++T S P+L S + P P + PTT QPG P Sbjct: 1326 RTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTA 1385 Query: 210 ---------------------HGPPPAGGPPPVRALTPLTSSYRDVPQP 237 H PP AG P P TS + P Sbjct: 1386 TETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYP 1434 Score = 30.8 bits (68), Expect = 7.3 Identities = 60/337 (17%), Positives = 112/337 (33%), Gaps = 38/337 (11%) Query: 60 HPIPAKTLNPVSGQSNYGGSQ----------GSGQTLNRPPVASNPVTPSLHSGPAPRMP 109 H +P T+ P + G + G+ Q L+ A + H+ Sbjct: 1646 HSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAE 1705 Query: 110 LPASQNPATTPMPSSSFLPEANLPPPLNWQYNYPSTASQTN---HCPRASS---QPTVSG 163 ++ TP P+S+ P + Q + ++T+ H +S+ + T + Sbjct: 1706 ATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTS 1765 Query: 164 NTSLTTNHQYVSSGYPSLQNSFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGGPPPVRA 223 TS+T NH + P + S P TT P P G P PV A Sbjct: 1766 TTSITPNHTSTGTRTPVAHTTSATSSRLPTPF------TTHSP--PTGTTPISSTGPVTA 1817 Query: 224 LTPLTSSYRDVPQ------PLFNSAVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQL 277 + T++ P P + + +T +T+ ++++ + + + P Sbjct: 1818 TSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTH--TVIIPTHTQMATSASIHSMPTG 1875 Query: 278 TNKNPKMSRSVGYSY---PSLPPGYQNTTPPGATGVPPSSLNYP---SGPQAFTQTPLGA 331 T P ++ G ++ P P + P + +S + P S TP Sbjct: 1876 TIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTST 1935 Query: 332 NHLTTSMSGLSLQPEGLRVVNLLQERNMLPSTPLKPP 368 ++T + + + R P T PP Sbjct: 1936 TNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPP 1972 >gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] Length = 638 Score = 59.3 bits (142), Expect = 2e-08 Identities = 74/289 (25%), Positives = 100/289 (34%), Gaps = 70/289 (24%) Query: 3 QPGIPASGGAPASLQAQNGAALASGSPYTN-GPVQNALLSSQESVSQGYNFQLPGSYPHP 61 +P PA+ P SL + S P+ N GP ++ G P S+PHP Sbjct: 345 RPAAPANNPPPPSLMSTT----QSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHP 400 Query: 62 IPAKTLNPVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAP---RMPLPASQNPAT 118 +P+ T +GG PP P P ++ GP P P P Q + Sbjct: 401 LPSLT-------GGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGS 453 Query: 119 TPMPSSSFL----------------------PEANLPPPLN-----WQYNY-------PS 144 TP+ S + P PPP + WQ P Sbjct: 454 TPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPP 513 Query: 145 TASQTNHCPRASSQPTVSGNTSLTTNH----------QYVSSGYPSLQNSFIKSGPSVPP 194 ++S + P Q T + TS T S G P +Q + + +PP Sbjct: 514 SSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGN--PTMVPLPP 571 Query: 195 LVNPPLPTTFQPGAPHGPPP-----AGGPPPVRALTPLTSSYRDVPQPL 238 V PPLP PGAP PPP AG P R + D P+PL Sbjct: 572 GVQPPLP----PGAPPPPPPPPPGSAGMMIPPRGGDGPSHESEDFPRPL 616 Score = 33.9 bits (76), Expect = 0.86 Identities = 47/186 (25%), Positives = 60/186 (32%), Gaps = 39/186 (20%) Query: 188 SGPSVPPLVNPPLPTTFQPGAPHGPPPAGGPPPVRALTPLTSSYRDVPQPLFNSAVNQEG 247 SGP+ PL + P P PA PPP P S P NS ++ Sbjct: 333 SGPATTPLASAPRPAA----------PANNPPP-----PSLMSTTQSRPPWMNSGPSES- 376 Query: 248 ITSNTNNGSMVVHSSYDEIEGGGLLATPQLTNKNPKMSRSVGYSYPSLPPGYQ-NTTPPG 306 Y + GGG P P S + PSL G+ + Sbjct: 377 -------------RPYHGMHGGG----PGGPGGGP---HSFPHPLPSLTGGHGGHPMQHN 416 Query: 307 ATGVPPSSLNYPSGPQAFTQTPLGANHLTTSMSGLSLQPEGLRVVNLLQERNMLPSTP-- 364 G PP + P P P G + L P G V L Q + M+P P Sbjct: 417 PNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMG 476 Query: 365 LKPPVP 370 + PP P Sbjct: 477 MMPPPP 482 >gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] Length = 639 Score = 58.9 bits (141), Expect = 3e-08 Identities = 69/266 (25%), Positives = 93/266 (34%), Gaps = 68/266 (25%) Query: 3 QPGIPASGGAPASLQAQNGAALASGSPYTN-GPVQNALLSSQESVSQGYNFQLPGSYPHP 61 +P PA+ P SL + S P+ N GP ++ G P S+PHP Sbjct: 345 RPAAPANNPPPPSLMSTT----QSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHP 400 Query: 62 IPAKTLNPVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAP---RMPLPASQNPAT 118 +P+ T +GG PP P P ++ GP P P P Q + Sbjct: 401 LPSLT-------GGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGS 453 Query: 119 TPMPSSSFL----------------------PEANLPPPLN-----WQYNY-------PS 144 TP+ S + P PPP + WQ P Sbjct: 454 TPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPP 513 Query: 145 TASQTNHCPRASSQPTVSGNTSLTTNH----------QYVSSGYPSLQNSFIKSGPSVPP 194 ++S + P Q T + TS T S G P +Q + + +PP Sbjct: 514 SSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGN--PTMVPLPP 571 Query: 195 LVNPPLPTTFQPGAPHGPPPAGGPPP 220 V PPLP PGAP PPP PPP Sbjct: 572 GVQPPLP----PGAPPPPPP---PPP 590 >gi|188497758 ubiquitin associated protein 2-like isoform a [Homo sapiens] Length = 1087 Score = 58.9 bits (141), Expect = 3e-08 Identities = 85/345 (24%), Positives = 133/345 (38%), Gaps = 52/345 (15%) Query: 15 SLQAQNGAALASGSPYTNG-PVQNALLSSQE--SVSQGYNFQLPG-SYPHPIPAKTLNPV 70 S++ G+A+ S SP T+ P N +S+ + + ++ L G S+ IP T Sbjct: 634 SVEGATGSAVKSDSPSTSSIPPLNETVSAASLLTTTNQHSSSLGGLSHSEEIPNTTTTQH 693 Query: 71 SG-----QSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAPRMPLPASQNPATTPMPSSS 125 S Q+ S SG+T + LH+ L +S + +T + S Sbjct: 694 SSTLSTQQNTLSSSTSSGRT---------STSTLLHTSVESEANLHSSSSTFSTTSSTVS 744 Query: 126 FLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNT---SLTTNHQYVSSGYPSLQ 182 PPP+ S +S N SG++ SL +N +S S+ Sbjct: 745 ------APPPV------VSVSSSLN-----------SGSSLGLSLGSNSTVTASTRSSVA 781 Query: 183 NSFIKSGPSVPPLVNPPLPTTF--QPGAPHG-PPPAGGPPPVRAL-TPLTSSYRDVPQPL 238 + K+ P++PP V P LP + PG H PP G ++ L T Y +P P Sbjct: 782 TTSGKAPPNLPPGVPPLLPNPYIMAPGLLHAYPPQVYGYDDLQMLQTRFPLDYYSIPFPT 841 Query: 239 FNSAVNQE--GITSNTNNGSMVVHSSYDEIEGGGL--LATPQLTNKNPKMSRSVGYSYPS 294 + + + SN +G + D LA PQ + + P+ Sbjct: 842 PTTPLTGRDGSLASNPYSGDLTKFGRGDASSPAPATTLAQPQQNQTQTHHTTQQTFLNPA 901 Query: 295 LPPGYQNTTPPGATGVPPSSLNYPSGPQAFTQTPLGANHLTTSMS 339 LPPGY T+ P TGVP + GP F P + ++S Sbjct: 902 LPPGYSYTSLPYYTGVPGLPSTFQYGPAVFPVAPTSSKQHGVNVS 946 Score = 33.1 bits (74), Expect = 1.5 Identities = 55/230 (23%), Positives = 75/230 (32%), Gaps = 41/230 (17%) Query: 57 SYPHPIPAKTL---------NPVSGQ-SNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAP 106 S P P P L NP SG + +G S P A+ P + Sbjct: 836 SIPFPTPTTPLTGRDGSLASNPYSGDLTKFGRGDASS-----PAPATTLAQPQQNQTQTH 890 Query: 107 RMPLPASQNPATTPMPSSSFLPEANLPPPLNWQYNY--------PSTASQ------TNHC 152 NPA P S + LP P L + Y P+++ Q N Sbjct: 891 HTTQQTFLNPALPPGYSYTSLPYYTGVPGLPSTFQYGPAVFPVAPTSSKQHGVNVSVNAS 950 Query: 153 PRASSQPTVSGNTSLTTNHQYVSSG----------YPSLQNSFIKSG-PSVPPLVNPPLP 201 QP+ G+ T SS Y Q SF K G S P + LP Sbjct: 951 ATPFQQPSGYGSHGYNTGVSVTSSNTGVPDISGSVYSKTQQSFEKQGFHSGTPAASFNLP 1010 Query: 202 TTFQPGAPHGPPPAGGPPPVRALTPLTSSYRDVPQPLFNSAVNQEGITSN 251 + G P P A PP + LT + Q + + + Q+G T + Sbjct: 1011 SALGSGGPINPATAAAYPPAPFMHILTPHQQPHSQ-ILHHHLQQDGQTGS 1059 >gi|188497756 ubiquitin associated protein 2-like isoform b [Homo sapiens] Length = 983 Score = 58.9 bits (141), Expect = 3e-08 Identities = 85/345 (24%), Positives = 133/345 (38%), Gaps = 52/345 (15%) Query: 15 SLQAQNGAALASGSPYTNG-PVQNALLSSQE--SVSQGYNFQLPG-SYPHPIPAKTLNPV 70 S++ G+A+ S SP T+ P N +S+ + + ++ L G S+ IP T Sbjct: 634 SVEGATGSAVKSDSPSTSSIPPLNETVSAASLLTTTNQHSSSLGGLSHSEEIPNTTTTQH 693 Query: 71 SG-----QSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAPRMPLPASQNPATTPMPSSS 125 S Q+ S SG+T + LH+ L +S + +T + S Sbjct: 694 SSTLSTQQNTLSSSTSSGRT---------STSTLLHTSVESEANLHSSSSTFSTTSSTVS 744 Query: 126 FLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNT---SLTTNHQYVSSGYPSLQ 182 PPP+ S +S N SG++ SL +N +S S+ Sbjct: 745 ------APPPV------VSVSSSLN-----------SGSSLGLSLGSNSTVTASTRSSVA 781 Query: 183 NSFIKSGPSVPPLVNPPLPTTF--QPGAPHG-PPPAGGPPPVRAL-TPLTSSYRDVPQPL 238 + K+ P++PP V P LP + PG H PP G ++ L T Y +P P Sbjct: 782 TTSGKAPPNLPPGVPPLLPNPYIMAPGLLHAYPPQVYGYDDLQMLQTRFPLDYYSIPFPT 841 Query: 239 FNSAVNQE--GITSNTNNGSMVVHSSYDEIEGGGL--LATPQLTNKNPKMSRSVGYSYPS 294 + + + SN +G + D LA PQ + + P+ Sbjct: 842 PTTPLTGRDGSLASNPYSGDLTKFGRGDASSPAPATTLAQPQQNQTQTHHTTQQTFLNPA 901 Query: 295 LPPGYQNTTPPGATGVPPSSLNYPSGPQAFTQTPLGANHLTTSMS 339 LPPGY T+ P TGVP + GP F P + ++S Sbjct: 902 LPPGYSYTSLPYYTGVPGLPSTFQYGPAVFPVAPTSSKQHGVNVS 946 >gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo sapiens] Length = 1560 Score = 58.2 bits (139), Expect = 4e-08 Identities = 97/366 (26%), Positives = 134/366 (36%), Gaps = 58/366 (15%) Query: 4 PGIPASGGAPASLQAQNGAALASGSPYTNGPVQNALLSSQESVSQGYNFQLP-GSYPH-P 61 P P + GA QA + A S +P P L S S Q P G PH P Sbjct: 735 PATPVAKGAGLGPQAPDSQA--SPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLP 792 Query: 62 IPAKTLNPVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAPRMP--LPAS---QNP 116 P T P S Q+++RPP P LH P P+ P LP QN Sbjct: 793 SPHPTRPPSRPPSR-------PQSVSRPPSE-----PPLHPCPPPQAPPTLPGIFVIQNQ 840 Query: 117 ATTPMPSSSFLPEANLPP--PLNWQYNYPS-TASQTNHCPRASSQPTVSGNTSLTTNHQY 173 P P+S+ P A PP PL Q P H P +S+ V+ ++ ++ Sbjct: 841 LGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPA 900 Query: 174 VSSGYPSLQNSFIKSGPSVPPLVNP-PLPTTFQPGAPHGPPPAGGPPPVRALTPLTSSYR 232 P+ + ++ PS P +P P PT P PPP PP R +T+ + Sbjct: 901 -----PTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPP----PPPRTFQMVTTPFP 951 Query: 233 DVPQPLFNSAVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQL-TNKNPKMSRSVGY- 290 +PQP + V + + GG A PQ T+ P S + Sbjct: 952 ALPQP-----------KALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVL 1000 Query: 291 -------SYPSLPPGYQNTTPPGATGVPPSSLNYPSGPQAFTQTPLGANHLTTSMSGLSL 343 P+ P P ATG+PP P+ +AF N + SG Sbjct: 1001 VSGQAPSGTPTAPSHAPAPAPMAATGLPPL---LPAENKAFASNLPTLNVAKAASSGPG- 1056 Query: 344 QPEGLR 349 +P GL+ Sbjct: 1057 KPSGLQ 1062 Score = 49.7 bits (117), Expect = 2e-05 Identities = 103/415 (24%), Positives = 143/415 (34%), Gaps = 81/415 (19%) Query: 4 PGIPASGGAPASLQAQ----NGAALASGSPYTNGP-VQNALLSSQESVSQGYNFQLPGSY 58 PG PA P L A G LA+ +P+T G + N +L++Q N P S Sbjct: 475 PGAPAVQ-LPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQ-------NLAGPLSL 526 Query: 59 PHPIPAKTLNPVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAPRMPLPASQNPAT 118 L P SG + + + +P + PV SL +G P PA PA Sbjct: 527 -----GPVLAPHSGAHSAHILSAAPIQVGQPALFQMPV--SLAAGSLPTQSQPAPAGPAA 579 Query: 119 TPMPSSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSGY 178 T + L LPP N P Q P + T LT Sbjct: 580 TTV-----LQGVTLPPSAVAMLNTPDGLVQ----PATPAAATGEAAPVLT---------- 620 Query: 179 PSLQNSFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGGPPPVRALTPLTSSYRDVPQPL 238 ++ P PP V+ PLP Q PP A P P A P ++ PQP Sbjct: 621 -------VQPAPQAPPAVSTPLPLGLQQPQAQQPPQA--PTPQAAAPPQATT----PQPS 667 Query: 239 FNSAVNQEGIT-SNTNNGSMVVHSSYDEIEGGGLLATPQLTNKNPKMSRSVGYSYP---- 293 A + E I + + + D ++ + PQ ++ P + S P Sbjct: 668 PGLASSPEKIVLGQPPSATPTAILTQDSLQ----MFLPQERSQQPLSAEGPHLSVPASVI 723 Query: 294 -SLPPGYQNTTP--PGATG------VPPSSLNYPSGPQAFTQTPLGANHLTTSMSGLSLQ 344 S PP Q+ P P A G P S + PQ PL ++S S Sbjct: 724 VSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQA 783 Query: 345 PEGLRVVNLLQERNMLPST-PLKPP--VPNLHEDIQKLNCNPELFRCTLTSIPQT 396 P G + LPS P +PP P+ + + + P L C P T Sbjct: 784 PLG--------DSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPT 830 Score = 36.6 bits (83), Expect = 0.13 Identities = 66/251 (26%), Positives = 91/251 (36%), Gaps = 49/251 (19%) Query: 7 PASGGAPASLQAQNGAALASGSPYT-----------NGP----VQNALLSSQESVSQGYN 51 PA GGA + GAA + P GP AL+ Q+ V++ + Sbjct: 136 PADGGAGPT--GAGGAAAVAAGPQALFPGSTDLLGLQGPPTVLTHQALVPPQDVVNKALS 193 Query: 52 FQLPGSYPHPIPAKTLNPVSG-QSNYGGSQG--SGQTLNRPPVASNPVTPSLHSGPAPRM 108 Q P P + TL P+ G Q GS G + TL P+ + P + Sbjct: 194 VQ-PFLQPVGLGNVTLQPIPGLQGLPNGSPGGATAATLGLAPI-------QVVGQPVMAL 245 Query: 109 PLPASQNPATTPMPSSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASS---QPTVSGNT 165 P SQ A +P S +L A P + P T + P+ + Q +S Sbjct: 246 NTPTSQLLAKQ-VPVSGYLASAAGP-------SEPVTLASAGVSPQGAGLVIQKNLSAAV 297 Query: 166 SLTTNHQYV---------SSGYPSLQNSFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAG 216 + T N V +G PS Q + G PLV P + P P PAG Sbjct: 298 ATTLNGNSVFGGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAG 357 Query: 217 G-PPPVRALTP 226 PP + LTP Sbjct: 358 VLPPKLYQLTP 368 Score = 35.8 bits (81), Expect = 0.23 Identities = 39/158 (24%), Positives = 56/158 (35%), Gaps = 12/158 (7%) Query: 13 PASLQAQNGAALASGSPYTNGPVQNALLSSQESVSQGYNFQLPGSYPHPIPAKTLNPVS- 71 P L ++G A GSP ++ LSS S S + L P+P++ P+ Sbjct: 1243 PTKLVIRHGGA--GGSPSVTWARASSSLSSSSSSSSAAS-SLDADEDGPMPSRNRPPIKT 1299 Query: 72 --GQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAPRMPLPASQ---NPATTPMPSSSF 126 +S G Q V N +H P P L ++ P P P+ Sbjct: 1300 YEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQM 1359 Query: 127 LPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGN 164 + PPP + TA HCPR + T N Sbjct: 1360 NGTVDHPPPAAPERKPLGTAP---HCPRLPLRKTYREN 1394 >gi|116284392 mucin 2 precursor [Homo sapiens] Length = 5179 Score = 57.0 bits (136), Expect = 1e-07 Identities = 64/260 (24%), Positives = 93/260 (35%), Gaps = 21/260 (8%) Query: 89 PPVASNPVTPSLHSGPAPRMPLPASQNPATTPMPSSSFLPEANLPPPLNWQYNYPSTASQ 148 P +P T + + P P P + P T P +++ P PP P T + Sbjct: 1519 PTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTP 1578 Query: 149 TNHCPRASSQPTVSGNT-SLTTNHQYVSSGYPSLQNSFIKSGPSVPPLVNPPLPTTFQPG 207 + S PT++ T TT ++ + + S P+ P+ P TT P Sbjct: 1579 SPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT 1638 Query: 208 APHGPPP--AGGPPPVRALTPLTSSYRDVPQPLFNSAVNQEGITSNTNNGSMVVHSSYDE 265 PPP PPP +P T++ P P IT+ T SS Sbjct: 1639 TTPSPPPTTTTTPPPTTTPSPPTTT---TPSP---------PITTTTTPPPTTTPSS--P 1684 Query: 266 IEGGGLLATPQLTNKNPKMSRSVGYSYPSLPPGYQNTTPPGATGVPPSSLNYPSGPQAFT 325 I T +T +P + S + + P +PP T PS PS P T Sbjct: 1685 ITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPS-PPTTT 1743 Query: 326 QTPLGANHLTTSMSGLSLQP 345 T L TT+ S L+ P Sbjct: 1744 MTTLPP---TTTSSPLTTTP 1760 Score = 55.5 bits (132), Expect = 3e-07 Identities = 72/316 (22%), Positives = 101/316 (31%), Gaps = 23/316 (7%) Query: 59 PHPIPAKTLNPVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAPRMPLPASQ-NPA 117 P P TL P + S T PP + P P + P P+ + Sbjct: 1408 PPPTSTTTLPPTTTPSP------PTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTT 1461 Query: 118 TTPMPSSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSG 177 TTP P+++ P P P + P+T + T S PT + T + + Sbjct: 1462 TTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTT 1521 Query: 178 YPSLQNSFIKSGPSV----PPLVNPPLPTTFQPGAPHGPPPAGGPPPVRALTPLTSSYRD 233 PS + + P PP P P T P P PPP TP ++ Sbjct: 1522 TPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLP--PTTTPSPPPTTTTTPPPTT--- 1576 Query: 234 VPQPLFNSAVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQLTNKNPKMSRSVGYSYP 293 P P + + IT+ T + TP P + + P Sbjct: 1577 TPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLP 1636 Query: 294 SL----PPGYQNTTPPGATGVPPSSLNYPSGPQAFTQTPLGANHLTTSMSGLSLQPEGLR 349 PP TTPP T P + PS P T TP TT S ++ P Sbjct: 1637 PTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTP---PPTTTPSSPITTTPSPPT 1693 Query: 350 VVNLLQERNMLPSTPL 365 PS+P+ Sbjct: 1694 TTMTTPSPTTTPSSPI 1709 Score = 42.7 bits (99), Expect = 0.002 Identities = 54/248 (21%), Positives = 82/248 (33%), Gaps = 20/248 (8%) Query: 109 PLPASQNPATTPMPSSSFLPEANLPPPLNWQYNYPST-------ASQTNHCPRASSQPTV 161 P P + P+ P +++ P PP P T + T P + P + Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPI 1458 Query: 162 SGNT----SLTTNHQYVSSGYPSLQNSFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGG 217 S T + T + + P+ S + + PP P P T P P P Sbjct: 1459 STTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP--PASTTT 1516 Query: 218 PPPVRALTPLTSSYRDVPQPLFNSAVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQL 277 PP +P T++ P S IT T+ ++ ++ P Sbjct: 1517 LPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTT 1576 Query: 278 TNKNPKMSRSVGYSYPSLPPGYQNTTPPGATGVPPSSLNYPSGPQAFTQTPLGANHLTTS 337 T P + PS PP TTPP T P + + P T +P +T Sbjct: 1577 TPSPPTTTT------PS-PPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPP 1629 Query: 338 MSGLSLQP 345 S +L P Sbjct: 1630 TSTTTLPP 1637 Score = 40.8 bits (94), Expect = 0.007 Identities = 68/304 (22%), Positives = 104/304 (34%), Gaps = 35/304 (11%) Query: 85 TLNRPPVASNPVTPSLHSGPAPRMPLPASQNPATTPM--------PSSSFLPEANLPPPL 136 T PP + P +P + + P+P + +P TTP PSS+ P PPP Sbjct: 1671 TTTTPPPTTTPSSP-ITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPS---PPPT 1726 Query: 137 NWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSGYPSLQNSFIKSGPSVP--P 194 P+T + PT + + TT S P + F + P+ P P Sbjct: 1727 TMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTT--PLPPSITPPTFSPFSTTTPTTPCVP 1784 Query: 195 LVNPPLPTTFQPGAPHGPPPAG---------GPPPVRALTPLTSSYRDVPQPLFNSAVNQ 245 L N G P+ P G GP ++ + Y DVP + Q Sbjct: 1785 LCN--WTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVP-------IGQ 1835 Query: 246 EGITSNTNNGSMVVHSSYDEIEGGGLLATPQLTNK-NPKMSRSVGYSYPSLPPGYQNTTP 304 G T + ++ + D+ GG + L + N + V +N TP Sbjct: 1836 LGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTP 1895 Query: 305 PGATGVPPSSLNYPSGPQAFTQTPLGANHLTTSMSGLSLQPEGLRVVNLLQERNMLPSTP 364 P T + ++ P+ TQTP TT+ + P G + TP Sbjct: 1896 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1955 Query: 365 LKPP 368 P Sbjct: 1956 TPTP 1959 Score = 36.6 bits (83), Expect = 0.13 Identities = 62/317 (19%), Positives = 106/317 (33%), Gaps = 38/317 (11%) Query: 59 PHPIPAKTLNPVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAPRMPLPASQNPAT 118 P P T V+ G+Q T P + VTP+ P P +Q P T Sbjct: 4035 PTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPT----PTPT----GTQTPTT 4083 Query: 119 TPMPSSSFLPEANLPPPLNWQYNYPSTASQT---NHCPRASSQPTVSGNTSLTT-NHQYV 174 TP+ +++ + P P T + T P + PT + T+ TT Sbjct: 4084 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4143 Query: 175 SSGYPSLQNSFIKSGPSVPPLVNPP-------LPTTFQPGAPHGPPPAG---GPPPVRAL 224 +G + + I + +V P P P T P P G GPP + Sbjct: 4144 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTST 4203 Query: 225 TPLTSSYRDVPQPLFNSAVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQLTNKNPKM 284 P+ P P ++ +S + ++ + IE +T+ P Sbjct: 4204 APIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIE---------MTSTAPPS 4254 Query: 285 SRSVGYSYPSLPPGYQNTTPPGATGVPPSSLNYPSGPQAFTQTPLGANHLTTSMSGLSLQ 344 + + P+ G +PP +T P + P + TT+ S + Sbjct: 4255 TPTA----PTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPT 4310 Query: 345 PEGLRVVNLLQERNMLP 361 P L ++++ + P Sbjct: 4311 PTPLSTPSIIRTTGLRP 4327 Score = 32.7 bits (73), Expect = 1.9 Identities = 55/237 (23%), Positives = 81/237 (34%), Gaps = 37/237 (15%) Query: 2 SQPGIPA-SGGAPASLQAQNGAALASGSPYTNGPVQNALLSSQESVSQGYNFQLPGSYPH 60 +Q G P + AP + + S +P T+ + L S +S LP + Sbjct: 4193 TQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLST-----LPPAIEM 4247 Query: 61 PIPAKTLNPVSGQSNYGGSQGSGQTLNRPP--VASNPVTPSL------HSGPAP---RMP 109 A P + + GG TL+ PP S P TP+ S P P + Sbjct: 4248 TSTAPPSTPTAPTTTSGG-----HTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTT 4302 Query: 110 LPASQNPATTPMPSSSFLPEANLPPPLNWQYNYPSTA------SQTNHCPRASSQPTVSG 163 ++ P TP+ + S + L P YPS+ + T + P G Sbjct: 4303 TTSAWTPTPTPLSTPSIIRTTGLRP-------YPSSVLICCVLNDTYYAPGEEVYNGTYG 4355 Query: 164 NTSLTTNHQYVSSGYPSLQNSFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGGPPP 220 +T N S N S PS P + PT +P + P G PP Sbjct: 4356 DTCYFVNCSL--SCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPP 4410 >gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens] Length = 1243 Score = 56.2 bits (134), Expect = 2e-07 Identities = 70/298 (23%), Positives = 106/298 (35%), Gaps = 51/298 (17%) Query: 2 SQPGIPASGGAPASLQAQNGAALASGSPYTNGPVQNALLSSQESVSQGYNFQLPGSYPHP 61 S PG P S G P S G+P + GP+ + P +P P Sbjct: 805 SSPGTPLSPGNPFS----------PGTPISPGPI--------------FPITSPPCHPSP 840 Query: 62 IPAKTLNPVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAPRMPLPASQNPATTPM 121 P +P+S SQ S P + P + S P P P S P T+P Sbjct: 841 SP---FSPIS-------SQVSSNPSPHPTSSPLPFSSSTPEFPVPLSQCPWSSLPTTSPP 890 Query: 122 PSSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSGYPSL 181 S + L P +P S T+ P ++ P +S ++ + V+ S Sbjct: 891 TFSPTCSQVTLSSPF-----FPPCPS-TSSFPSTTAAPLLSLASAFSLAVMTVAQSLLSP 944 Query: 182 QNSFIKSGPSVP--PLVNPPLPTTFQPGAPHGPPP-------AGGPPPVRALTPLTSSYR 232 + P P PL + PLP PG P P PPP R L P + Sbjct: 945 SPGLLSQSPPAPPSPLPSLPLPPPVAPGGQESPSPHTAEVESEASPPPARPL-PGEARLA 1003 Query: 233 DVPQPLFNSAVNQEGITSNTNNGS-MVVHSSYDEIEGGGLLATPQLTNKNPKMSRSVG 289 + + V + +TS+ + + + + G +TPQLT+++ S G Sbjct: 1004 PISEEGKPQLVGRFQVTSSKEPAEPLPLQPTSPTLSGSPKPSTPQLTSESSDTEDSAG 1061 >gi|125858485 hypothetical protein LOC80209 isoform 2 [Homo sapiens] Length = 922 Score = 54.7 bits (130), Expect = 5e-07 Identities = 92/339 (27%), Positives = 124/339 (36%), Gaps = 50/339 (14%) Query: 29 PYTNGPV--QNALLSSQESVSQGYNFQLPGSY-----------PHPIPAKTLNPVSGQSN 75 PYT PV +N LS+ Q F P S P P T +PV ++ Sbjct: 213 PYTPNPVGTENEDLSNPSKPIQNQTFSTPASQLFSPHGSNPSTPAATPVPTASPVKAINH 272 Query: 76 YGGSQG---SGQTLNRP--PVASNPVTPSLHSGPAPRMPLP--------------ASQNP 116 S SG L PV V+ ++H+ P P +P P + + Sbjct: 273 PSASAAATVSGMNLLNTVLPVFPGQVSSAVHT-PQPSIPNPTVIRTPSLPTAPVTSIHST 331 Query: 117 ATTPMPSSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSS 176 TTP+PS F +LP P T T SS+ S + T+ SS Sbjct: 332 TTTPVPSI-FSGLVSLPGPSATPTAATPTPGPTPRSTLGSSEAFASTSAPFTSLPFSTSS 390 Query: 177 GYPSLQNSFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGGPPPVRALTPLTSSYRDVPQ 236 S N S SV + PLP T Q + P AGG TP + V Sbjct: 391 SAASTSNPNSASLSSVFAGLPLPLPPTSQGLSNPTPVIAGGS------TPSVAGPLGVNS 444 Query: 237 PLFNSAVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQLTNKNPKMSRSVGYS--YPS 294 PL ++ + +TSN N ++ S+ GL + LT +N S S PS Sbjct: 445 PLLSAL--KGFLTSNDTN--LINSSALSSAVTSGLASLSSLTLQNSDSSASAPNKCYAPS 500 Query: 295 LPPGYQNTTPPGAT---GVPPSSLNYPSGPQAF-TQTPL 329 P Q T+ PG G+P N S P Q+PL Sbjct: 501 AIPTPQRTSTPGLALFPGLPSPVANSTSTPLTLPVQSPL 539 >gi|125656155 hypothetical protein LOC80209 isoform 1 [Homo sapiens] Length = 944 Score = 54.7 bits (130), Expect = 5e-07 Identities = 92/339 (27%), Positives = 124/339 (36%), Gaps = 50/339 (14%) Query: 29 PYTNGPV--QNALLSSQESVSQGYNFQLPGSY-----------PHPIPAKTLNPVSGQSN 75 PYT PV +N LS+ Q F P S P P T +PV ++ Sbjct: 235 PYTPNPVGTENEDLSNPSKPIQNQTFSTPASQLFSPHGSNPSTPAATPVPTASPVKAINH 294 Query: 76 YGGSQG---SGQTLNRP--PVASNPVTPSLHSGPAPRMPLP--------------ASQNP 116 S SG L PV V+ ++H+ P P +P P + + Sbjct: 295 PSASAAATVSGMNLLNTVLPVFPGQVSSAVHT-PQPSIPNPTVIRTPSLPTAPVTSIHST 353 Query: 117 ATTPMPSSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSS 176 TTP+PS F +LP P T T SS+ S + T+ SS Sbjct: 354 TTTPVPSI-FSGLVSLPGPSATPTAATPTPGPTPRSTLGSSEAFASTSAPFTSLPFSTSS 412 Query: 177 GYPSLQNSFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGGPPPVRALTPLTSSYRDVPQ 236 S N S SV + PLP T Q + P AGG TP + V Sbjct: 413 SAASTSNPNSASLSSVFAGLPLPLPPTSQGLSNPTPVIAGGS------TPSVAGPLGVNS 466 Query: 237 PLFNSAVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQLTNKNPKMSRSVGYS--YPS 294 PL ++ + +TSN N ++ S+ GL + LT +N S S PS Sbjct: 467 PLLSAL--KGFLTSNDTN--LINSSALSSAVTSGLASLSSLTLQNSDSSASAPNKCYAPS 522 Query: 295 LPPGYQNTTPPGAT---GVPPSSLNYPSGPQAF-TQTPL 329 P Q T+ PG G+P N S P Q+PL Sbjct: 523 AIPTPQRTSTPGLALFPGLPSPVANSTSTPLTLPVQSPL 561 >gi|116284398 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 53.5 bits (127), Expect = 1e-06 Identities = 93/351 (26%), Positives = 119/351 (33%), Gaps = 102/351 (29%) Query: 55 PGSYPHPIPAKTLNPVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAPRMPLPASQ 114 P S P P+P+ T P+ + GS PPV P PS GP P P P ++ Sbjct: 180 PDSIPPPVPS-TPRPIQSSPHNRGS---------PPVPGGPRQPS--PGPTPP-PFPGNR 226 Query: 115 NPAT-------TPMPSSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSL 167 A +P+ SSS P +N PP P T S+ P V Sbjct: 227 GTALGGGSIRQSPLSSSS--PFSNRPP-------LPPTPSRALDDKPPPPPPPVGNR--- 274 Query: 168 TTNHQYVSSGYPSLQNSFIKSGPSVPPLVN-PPLPTTFQPGAPHGPPPAGGPPPVRALTP 226 PS+ + P PP N PP+P+T +P A PP PP Sbjct: 275 -----------PSIHREAV---PPPPPQNNKPPVPSTPRPSASSQAPPPPPPPS------ 314 Query: 227 LTSSYRDVPQPLFNSAVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQLTNKNPKMSR 286 R P PL S+ S DE TP+L +N +S Sbjct: 315 -----RPGPPPLPPSS------------------SGNDE--------TPRLPQRNLSLSS 343 Query: 287 SVGYSYPSLP-PGYQNTTPPGATGVPPSSLNYP---SGP---------QAFTQTPLGANH 333 S P LP PG PP + PP + P SGP T L A Sbjct: 344 ST----PPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATP 399 Query: 334 LTTSMSGLSLQPEGLRVVNLLQERNMLPSTPLKPPVPNLHEDIQKLNCNPE 384 S SG+ G R L +R + P PP ++ Q C E Sbjct: 400 QLPSRSGVDSPRSGPR-PPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDE 449 >gi|38373695 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 53.5 bits (127), Expect = 1e-06 Identities = 93/351 (26%), Positives = 119/351 (33%), Gaps = 102/351 (29%) Query: 55 PGSYPHPIPAKTLNPVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAPRMPLPASQ 114 P S P P+P+ T P+ + GS PPV P PS GP P P P ++ Sbjct: 180 PDSIPPPVPS-TPRPIQSSPHNRGS---------PPVPGGPRQPS--PGPTPP-PFPGNR 226 Query: 115 NPAT-------TPMPSSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSL 167 A +P+ SSS P +N PP P T S+ P V Sbjct: 227 GTALGGGSIRQSPLSSSS--PFSNRPP-------LPPTPSRALDDKPPPPPPPVGNR--- 274 Query: 168 TTNHQYVSSGYPSLQNSFIKSGPSVPPLVN-PPLPTTFQPGAPHGPPPAGGPPPVRALTP 226 PS+ + P PP N PP+P+T +P A PP PP Sbjct: 275 -----------PSIHREAV---PPPPPQNNKPPVPSTPRPSASSQAPPPPPPPS------ 314 Query: 227 LTSSYRDVPQPLFNSAVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQLTNKNPKMSR 286 R P PL S+ S DE TP+L +N +S Sbjct: 315 -----RPGPPPLPPSS------------------SGNDE--------TPRLPQRNLSLSS 343 Query: 287 SVGYSYPSLP-PGYQNTTPPGATGVPPSSLNYP---SGP---------QAFTQTPLGANH 333 S P LP PG PP + PP + P SGP T L A Sbjct: 344 ST----PPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATP 399 Query: 334 LTTSMSGLSLQPEGLRVVNLLQERNMLPSTPLKPPVPNLHEDIQKLNCNPE 384 S SG+ G R L +R + P PP ++ Q C E Sbjct: 400 QLPSRSGVDSPRSGPR-PPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDE 449 >gi|31543543 retinoic acid induced 17 [Homo sapiens] Length = 1067 Score = 53.1 bits (126), Expect = 1e-06 Identities = 67/235 (28%), Positives = 87/235 (37%), Gaps = 32/235 (13%) Query: 1 MSQPGI--PASGGA---PASLQAQNGAALASGSPYTNGPVQNALLSSQESVSQGYNFQL- 54 M+QPG PAS G PAS+ A + SG P + +S + Q Q Sbjct: 331 MNQPGPRGPASMGGSMNPASMAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTY 390 Query: 55 PGSYPHPIPAKTLN-PVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAPRMPLPAS 113 PG P +P + + P G+ NYG Q P + P P + P P PL + Sbjct: 391 PGPRPQSLPIQNIKRPYPGEPNYGNQQYG-------PNSQFPTQPGQYPAPNPPRPLTSP 443 Query: 114 QNPATT--PMPSSSFLPEANLPPPLNW-QYNYPSTASQTNHCPRASSQPTVS-GNTSLTT 169 P PSS P PP +N QY P + N+ SS S GN + Sbjct: 444 NYPGQRMPSQPSSGQYP----PPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPP 499 Query: 170 NH----QYVSSGYPSLQNSFIKSGPSVPPL------VNPPLPTTFQPGAPHGPPP 214 Y S P + G S+PP V PP P +P PPP Sbjct: 500 RPVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQDVKPPFPPDIKPNMSALPPP 554 Score = 32.0 bits (71), Expect = 3.3 Identities = 77/360 (21%), Positives = 118/360 (32%), Gaps = 50/360 (13%) Query: 27 GSPYTNG-PVQNALLSSQESVSQGYNFQLPGSYPHPIPAKTLNPVSGQSNYGGSQGSGQT 85 G+P +G N L+S + Q F P +++ G+ NY GS G G + Sbjct: 197 GNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQSMY---GRPNYPGSGGFGAS 253 Query: 86 LNRPPVASNPVTPSLHSGPAPRMPLPASQ------NPATTPMPSSSFLPEANLPPPLNWQ 139 P A + H+ P PA+ A +++ A L N Sbjct: 254 YPGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAATATATATATVAALQETQNKD 313 Query: 140 YN-YPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSGYPSLQNSFIKSGPSVPPL-VN 197 N Y + + +QP G S+ S S+ SG S PP+ +N Sbjct: 314 INQYGPMGPTQAYNSQFMNQPGPRGPASMGG-----SMNPASMAAGMTPSGMSGPPMGMN 368 Query: 198 PPLPTTFQPGAPHGP--PPAGGPPPVRALTPLTSSYRDVPQPLFNSAVNQEGITSNTNNG 255 P P P HG P P P P+ + R P N N Sbjct: 369 QPRPPGISPFGTHGQRMPQQTYPGPRPQSLPIQNIKRPYPG------------EPNYGNQ 416 Query: 256 SMVVHSSYDEIEGGGLLATPQLTNKNPKMSRSVGYSYPSLPPGYQNTTPPGATGVPPSSL 315 +S + G P P+ S Y PG + + P + PP ++ Sbjct: 417 QYGPNSQFPTQPGQYPAPNP------PRPLTSPNY------PGQRMPSQPSSGQYPPPTV 464 Query: 316 NYPS--GPQAF---TQTPLGANHLTTSMSGLSLQPEGLRVVNLLQERNMLPSTPLKPPVP 370 N P+ F T G+++ S ++ P + V N + +P P P P Sbjct: 465 NMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPVAN--YPHSPVPGNPTPPMTP 522 >gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] Length = 5765 Score = 52.0 bits (123), Expect = 3e-06 Identities = 76/305 (24%), Positives = 108/305 (35%), Gaps = 28/305 (9%) Query: 62 IPAKTLNPVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAPRMPLPASQNPATTPM 121 +P + S G+ T P V S+ TP S P LPA ++ ATTP Sbjct: 3736 VPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATP--FSSPGTATALPALRSTATTPT 3793 Query: 122 PSS-SFLPEANLPPPLNW-QYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSGYP 179 +S + +P ++L W + + +T + T SS P + +++ T + Sbjct: 3794 ATSFTAIPSSSL--GTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATG 3851 Query: 180 SLQNSFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGGPPPV---RALTPLTSSYRDVPQ 236 S+ G + V P TT P P PPV TP TS P Sbjct: 3852 SVATPSSTPGTAHTTKV-PTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPS 3910 Query: 237 PLFNSAVNQEGITSNTN---NGSMVVHSSYDEIEGGGLLATPQLTNKNPKMSRSVGYSYP 293 + + +T+ T GSM SS + G P L ++ + + P Sbjct: 3911 SVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSG----TPPSLITTATTITATGSTTNP 3966 Query: 294 SLPPGYQNTTP-------PGATGVPPSSLNYPSGPQAFTQTPLGANHLTTSMSGLSLQPE 346 S PG TTP T SS PS T TP N T + G SL P Sbjct: 3967 SSTPG---TTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPN-TTATTHGRSLSPS 4022 Query: 347 GLRVV 351 V Sbjct: 4023 SPHTV 4027 Score = 51.2 bits (121), Expect = 5e-06 Identities = 73/282 (25%), Positives = 104/282 (36%), Gaps = 28/282 (9%) Query: 85 TLNRPPVASNPVTPSLHSGPAPRMPLPASQNPATTPMPSS-SFLPEANLPPPLNW-QYNY 142 T P V S+ TPS S P LPA ++ ATTP +S + +P ++L W + + Sbjct: 1945 TATTPTVTSSKATPS--SSPGTATALPALRSTATTPTATSVTPIPSSSL--GTTWTRLSQ 2000 Query: 143 PSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSGYPSLQNSFIKSGPSVPPLVNPPLPT 202 +T + T SS P + +++ T + S+ G + V P T Sbjct: 2001 TTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKV-PTTTT 2059 Query: 203 TFQPGAPHGPPPAGGPPPV---RALTPLTSSYRDVPQPLFNSAVNQEGITSNTN---NGS 256 T P P PPV TP T P + + +T+ T GS Sbjct: 2060 TGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGS 2119 Query: 257 MVVHSSYDEIEGGGLLATPQLTNKNPKMSRSVGYSYPSLPPGYQNTTP-------PGATG 309 M SS + G P LT ++ + + PS PG TTP T Sbjct: 2120 MATPSSSTQTSG----TPPSLTTTATTITATGSTTNPSSTPG---TTPIPPVLTTTATTP 2172 Query: 310 VPPSSLNYPSGPQAFTQTPLGANHLTTSMSGLSLQPEGLRVV 351 S+ PS T TP N + T+ G SL P V Sbjct: 2173 AATSNTVTPSSALGTTHTPPVPNTMATT-HGRSLPPSSPHTV 2213 Score = 50.8 bits (120), Expect = 7e-06 Identities = 76/283 (26%), Positives = 104/283 (36%), Gaps = 30/283 (10%) Query: 85 TLNRPPVASNPVTPSLHSGPAPRMPLPASQNPATTPMPSS-SFLPEANLPPPLNWQYNYP 143 T P V S+ TPS S P LPA ++ ATTP +S + +P ++L + + Sbjct: 3202 TATTPTVISSRATPS--SSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWT-RLSQT 3258 Query: 144 STASQTNHCPRASSQP-TVSGNTSLTTNHQYVSSGYPSLQNSFIKSGPSVPPLVNPP-LP 201 +T + T SS P TV +T LTT + + + S P + +P Sbjct: 3259 TTPTATMSTATPSSTPETVHTSTVLTTTTTTTRA------TGSVATPSSTPGTAHTTKVP 3312 Query: 202 TTFQPG---APHGPPPAGGPPPV---RALTPLTSSYRDVPQPLFNSAVNQEGITSNTNN- 254 TT G P P PPV TP T P + + +T+ T Sbjct: 3313 TTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTV 3372 Query: 255 --GSMVVHSSYDEIEGGGLLATPQLTNKNPKMSRSVGYSYPSLPPGYQNTTP----PGAT 308 GSM SS + G P LT ++ + + PS PG P T Sbjct: 3373 ATGSMATPSSSTQTSG----TPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATT 3428 Query: 309 GVPPSSLNYPSGPQAFTQTPLGANHLTTSMSGLSLQPEGLRVV 351 SS PS T TP N T + G SL P V Sbjct: 3429 PAATSSTVTPSSALGTTHTPPVPN-TTATTHGRSLPPSSPHTV 3470 Score = 50.8 bits (120), Expect = 7e-06 Identities = 72/297 (24%), Positives = 105/297 (35%), Gaps = 33/297 (11%) Query: 62 IPAKTLNPVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAPRMPLPASQNPATTPM 121 +P + S G+ T P V S+ TPS S P LPA ++ ATTP Sbjct: 4464 VPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPS--SSPGTATALPALRSTATTPT 4521 Query: 122 PSS-SFLPEANLPPPLNW-QYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSGYP 179 +S + +P ++L W + + +T + T SS P +++ T + Sbjct: 4522 ATSFTAIPSSSL--GTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATG 4579 Query: 180 SLQNSFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGGPPPV--------RALTPLTSSY 231 S+ G + V P TT P P PPV TP TS Sbjct: 4580 SVATPSSTPGTAHTTKV-PTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGS 4638 Query: 232 RDVPQPLFNSAVNQEGITSNTN---NGSMVVHSSYDEIEGGGLLATPQLTNKNPKMSRSV 288 P + + +T+ T GSM SS + G P LT ++ + Sbjct: 4639 TVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSG----TPPSLTTTATTITATG 4694 Query: 289 GYSYPSLPPGYQNTTP--------PGATGVPPSSLNYPSGPQAFTQTPLGANHLTTS 337 + PS PG TP P AT S S P+ T P+ + T S Sbjct: 4695 STTNPSSTPGTTPITPVLTSTATTPAATS---SKATSSSSPRTATTLPVLTSTATKS 4748 Score = 47.8 bits (112), Expect = 6e-05 Identities = 77/304 (25%), Positives = 109/304 (35%), Gaps = 26/304 (8%) Query: 62 IPAKTLNPVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAPRMPLPASQNPATTPM 121 +P + S G+ T P V S+ TP S P LPA ++ ATTP Sbjct: 2479 VPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATP--FSSPGTATALPALRSTATTPT 2536 Query: 122 PSS-SFLPEANLPPPLNW-QYNYPSTASQTNHCPRASSQP-TVSGNTSLTTNHQYV-SSG 177 +S + +P ++L W + + +T + T SS P TV +T LTT ++G Sbjct: 2537 ATSFTAIPSSSLGT--TWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATG 2594 Query: 178 YPSLQNSFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGGPPPV---RALTPLTSSYRDV 234 + +S + + L TT P P PV TP T Sbjct: 2595 SVATPSSTPGTAHTTKVLTTT---TTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVT 2651 Query: 235 PQPLFNSAVNQEGITSNTNN---GSMVVHSSYDEIEGGGLLATPQLTNKNPKMSRSVGYS 291 P + + +T+ T GSM SS + G P LT ++ + + Sbjct: 2652 PSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSG----TPPSLTTTATTITATGSTT 2707 Query: 292 YPSLPPGYQNTTP----PGATGVPPSSLNYPSGPQAFTQTPLGANHLTTSMSGLSLQPEG 347 PS PG P T SS PS T TP N T + G SL P Sbjct: 2708 NPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPN-TTATTHGRSLSPSS 2766 Query: 348 LRVV 351 V Sbjct: 2767 PHTV 2770 Score = 44.7 bits (104), Expect = 5e-04 Identities = 74/330 (22%), Positives = 108/330 (32%), Gaps = 48/330 (14%) Query: 64 AKTLNPVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAPRMPLPASQNPATTPMPS 123 A T + + G+ T P + T + S P P + TTP S Sbjct: 3844 ATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTS 3903 Query: 124 SSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSGYPSLQN 183 S + PS+ T H P T LTT V++G + + Sbjct: 3904 GSTVT--------------PSSVPGTTHTP-----------TVLTTTTTTVATGSMATPS 3938 Query: 184 SFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGGPPPV------RALTPLTSSYRDVP-Q 236 S ++ + P L+ T G+ P G P+ A TP +S P Sbjct: 3939 SSTQTSGTPPSLITTATTIT-ATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSS 3997 Query: 237 PLFNSAVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQLTNKNPKMSRSVGYSY-PSL 295 L + T+ T +G + SS + AT S G S+ P+ Sbjct: 3998 ALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAA 4057 Query: 296 PPGYQNTTPPGATGVPPSSLNYPSGPQAFTQTPLGANHLT-TSMSGLSLQPEGLRVVNLL 354 G + P + PSS S P T TP H T TS + + P R L Sbjct: 4058 TTGTTQHSTPALSSPHPSSRTTESPPSPGTTTP---GHTTATSRTTATATPSKTRTSTL- 4113 Query: 355 QERNMLPSTPLKPPVPNLHEDIQKLNCNPE 384 LPS+P P+ + C P+ Sbjct: 4114 -----LPSSPTSAPITT----VVTTGCEPQ 4134 Score = 38.9 bits (89), Expect = 0.027 Identities = 69/335 (20%), Positives = 109/335 (32%), Gaps = 58/335 (17%) Query: 64 AKTLNPVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAPRMPLPASQNPATTPMPS 123 A T + + G+ T P + T + S P + P + TTP Sbjct: 2030 ATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTR 2089 Query: 124 SSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSGYPSLQN 183 S + +++P T T LTT V++G + + Sbjct: 2090 GSTVTPSSIP-------------------------GTTHTATVLTTTTTTVATGSMATPS 2124 Query: 184 SFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGGPPPV------RALTPLTSSYRDVP-Q 236 S ++ PP + T G+ P G P+ A TP +S P Sbjct: 2125 SSTQTS-GTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSS 2183 Query: 237 PLFNSAVNQEGITSNTNNGSMVVHSSYDEIE------GGGLLATPQLTNKNPKMSRSVGY 290 L + T T +G + SS + G+L T +T + S ++ Sbjct: 2184 ALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTL-- 2241 Query: 291 SYPSLPPGYQNTTPPGATGVPPSSLNYPSGPQAFTQTPLGANHLT-TSMSGLSLQPEGLR 349 + G + P + PSS S P T TP H T TS + + P R Sbjct: 2242 ---AATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTP---GHTTATSRTTATATPSKTR 2295 Query: 350 VVNLLQERNMLPSTPLKPPVPNLHEDIQKLNCNPE 384 L LPS+P P+ + + C P+ Sbjct: 2296 TSTL------LPSSPTSAPITT----VVTMGCEPQ 2320 Score = 36.2 bits (82), Expect = 0.17 Identities = 65/317 (20%), Positives = 103/317 (32%), Gaps = 56/317 (17%) Query: 81 GSGQTLNRPPVASNPVTPSLHSGPAPRMPLPASQNPATTPMPSSSFLPEANLPPPLNWQY 140 G+ T P + T + S P + P + TTP S + +++P Sbjct: 3304 GTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIP------- 3356 Query: 141 NYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSGYPSLQNSFIKSGPSVPPLVNPPL 200 T T LTT V++G + +S ++ PP + Sbjct: 3357 ------------------GTTHTATVLTTTTTTVATGSMATPSSSTQTS-GTPPSLTTTA 3397 Query: 201 PTTFQPGAPHGPPPAGGPPPV------RALTPLTSSYRDVP-QPLFNSAVNQEGITSNTN 253 T G+ P G P+ A TP +S P L + T+ T Sbjct: 3398 TTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATT 3457 Query: 254 NGSMVVHSSYDEIE------GGGLLATPQLTNKNPKMSRSVGYSYPSLPPGYQNTTPPGA 307 +G + SS + G+L T +T + S + P+ + P Sbjct: 3458 HGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHT-----PAATTSTTQHSTPAL 3512 Query: 308 TGVPPSSLNYPSGPQAFTQTPLGANHLTTSMSGLSLQPEGLRVVNLLQERNMLPSTPLKP 367 + PSS S P T TP + TS + + P R L LPS+P Sbjct: 3513 SSPHPSSRTTESPPSPGTTTP--GHTRGTSRTTATATPSKTRTSTL------LPSSPTSA 3564 Query: 368 PVPNLHEDIQKLNCNPE 384 P+ + C P+ Sbjct: 3565 PITT----VVTTGCEPQ 3577 Score = 35.0 bits (79), Expect = 0.39 Identities = 51/227 (22%), Positives = 85/227 (37%), Gaps = 12/227 (5%) Query: 118 TTPMPSSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSG 177 +TP SS+ P + P W P+T + T +++ PT + T+ ++ Sbjct: 1890 STPATSSTATPSST--PGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTAT 1947 Query: 178 YPSLQNSFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGGPPPVRALTPLTSSYRDVPQP 237 P++ +S K+ PS P LP + A + P P +L + P Sbjct: 1948 TPTVTSS--KATPSSSPGTATALP-ALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTP 2004 Query: 238 LFNSAVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQL------TNKNPKMSRSVGYS 291 + T T + S V+ ++ G +ATP T K P + + + Sbjct: 2005 TATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTA 2064 Query: 292 YPSLPPGYQNTTPPG-ATGVPPSSLNYPSGPQAFTQTPLGANHLTTS 337 PS PG T P +T P++ P + T A LTT+ Sbjct: 2065 TPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTT 2111 Score = 30.8 bits (68), Expect = 7.3 Identities = 68/324 (20%), Positives = 107/324 (33%), Gaps = 27/324 (8%) Query: 118 TTPMPSSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSG 177 TT S+ P + P W PST + T P S+ S + T H ++ Sbjct: 4433 TTASTGSTATPSST--PGTTWILTEPSTTA-TVTVPTGSTATASSTQATAGTPHVSTTAT 4489 Query: 178 YPSLQNSFIKSGPSVPPLVNPPLPTTFQPGA-PHGPPPAGGPPPVRALTPLTSSYRDVPQ 236 P++ +S K+ PS P LP P P T S P Sbjct: 4490 TPTVTSS--KATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPT 4547 Query: 237 PLFNSAVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQLTN---KNPKMSRSVGYSYP 293 ++A T T + S V+ ++ G +ATP T K+ + + Sbjct: 4548 ATMSTATPSS--TPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFT 4605 Query: 294 SLPPGYQNTTPPGATGVPPSSLNYPSGPQAFTQTPLGANHLTTSMSGLSLQPEGLRVVNL 353 + P ++ PG PP ++ + P T T G+ +S+ G + L Sbjct: 4606 ATP-----SSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTPSSIPGTTHTARVLTTTTT 4660 Query: 354 LQERNMLPSTPLKPPVPNLHEDIQKLNCNPELFRCTLTSIPQTQALLNKAKLPLGLLLHP 413 + +TP + + P T T+I T + N + P + P Sbjct: 4661 TVATGSM-ATP---------SSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPITP 4710 Query: 414 -FKDLVQLPVVTSSTIVRCRSCRT 436 P TSS S RT Sbjct: 4711 VLTSTATTPAATSSKATSSSSPRT 4734 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 51.6 bits (122), Expect = 4e-06 Identities = 42/155 (27%), Positives = 63/155 (40%), Gaps = 9/155 (5%) Query: 90 PVASNPVTPSLHSGPAPRMPLPASQNPATTPMPSSSFLPEANLPPPLNWQYNYPSTASQT 149 P+ +P++P S P+P + P S P +P+ S F PPP + P AS+ Sbjct: 514 PLEESPLSPPEESPPSPALETPLSPPPEASPL-SPPFEESPLSPPPEELPTSPPPEASRL 572 Query: 150 NHCPRASSQPTVSGNTSLTTNHQYVSSGYPSLQNSFIKSGPSVPPLVNPPLPTTFQP--- 206 + P S + ++ + S +P + S + P PL PP + P Sbjct: 573 SPPPEESPMSPPPEESPMSPPPE-ASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPE 631 Query: 207 GAPHGPPPAGGP----PPVRALTPLTSSYRDVPQP 237 +P PPP P P V L+PL R P P Sbjct: 632 DSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPP 666 Score = 38.5 bits (88), Expect = 0.035 Identities = 46/163 (28%), Positives = 60/163 (36%), Gaps = 35/163 (21%) Query: 2 SQPGIPASGGAPA--SLQAQNGAALASG------SPYTNGPVQNALLSSQESVSQGYNFQ 53 S G+P G P L+AQ LA SP +Q L+ Q SQ Q Sbjct: 4181 SGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVR-Q 4239 Query: 54 LPGSYPHPIPAKTLNPVSG----QSNYGG----------SQGSGQTLNRPP--------V 91 P P+ P +P+ G Q GG G+G PP + Sbjct: 4240 TP---PYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGAL 4296 Query: 92 ASNPVTPSLHSGPAPRMPLPASQNPATTPMPSSSFLPEANLPP 134 ++ PV +H P P P + P+ P PSS EA LPP Sbjct: 4297 STGPVLGPVHPTPPPSSP-QEPKRPSQLPSPSSQLPTEAQLPP 4338 Score = 35.0 bits (79), Expect = 0.39 Identities = 38/140 (27%), Positives = 49/140 (35%), Gaps = 20/140 (14%) Query: 89 PPVASNPVTPSLHSGPAPRMPLPASQNPATTPMPSSSFLPEANLPPPLNWQYNYPSTASQ 148 P ++ P P L P P S+ P +P P S L PPL+ + P + Sbjct: 813 PHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKP--PEE 870 Query: 149 TNHCPRASSQPTV--SGNTSLTTNHQYVSSGYPSLQNSFIKSGPSVPPLVNPPLPTTFQP 206 CP P G SL+ G P+L S P PPL P P Sbjct: 871 PGQCPAPEELPLFPPPGEPSLSP-----LLGEPAL------SEPGEPPLSPLPEELPLSP 919 Query: 207 G-----APHGPPPAGGPPPV 221 +P PP PPP+ Sbjct: 920 SGEPSLSPQLMPPDPLPPPL 939 Score = 32.7 bits (73), Expect = 1.9 Identities = 39/157 (24%), Positives = 58/157 (36%), Gaps = 24/157 (15%) Query: 89 PPVASNPVTPSLHSGPAPRMPLPASQNPATTPMPSSSFLPEA-----------NLPPPLN 137 PP +P++P P P + +P +P+S LPEA PPP Sbjct: 442 PPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASP-LPEALHLSRPLEESPLSPPPEE 500 Query: 138 WQYNYPSTAS------QTNHCPRASSQPTVSGNTSLTTNHQYVSSGYPSLQNSFIKSGPS 191 + P +S ++ P S P+ + T L+ + S P + S + P Sbjct: 501 SPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPE-ASPLSPPFEESPLSPPPE 559 Query: 192 VPPLVNPPLPTTFQP---GAPHGPPPAGGP--PPVRA 223 P PP + P +P PPP P PP A Sbjct: 560 ELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEA 596 Score = 32.7 bits (73), Expect = 1.9 Identities = 69/317 (21%), Positives = 102/317 (32%), Gaps = 49/317 (15%) Query: 90 PVASNPVTPSLHSGPAPRMPLPASQNPATTPMPSSSFLPEANLPPPLN------------ 137 P S P P L P +PL S P+ +P +P LPPPL+ Sbjct: 898 PALSEPGEPPLSPLPE-ELPLSPSGEPSLSPQ----LMPPDPLPPPLSPIITAAAPPALS 952 Query: 138 --WQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSGYPSLQNSFIKSGPSVP-- 193 + YP A + + P + T ++ + + + + P P Sbjct: 953 PLGELEYPFGAKGDSDPESPLAAPIL--ETPISPPPEANCTDPEPVPPMILPPSPGSPVG 1010 Query: 194 ---PLVNPPLPTTFQPGAPHGPPPAGGPPPVRALTPLTSSYRDVPQPLFNSAVNQEGITS 250 P++ PLP P H P PP + L S VP PL S + + S Sbjct: 1011 PASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLS---VPSPL--SPIGKVVGVS 1065 Query: 251 NTNNGSMVVHSSYDEIEGGGLLATPQLTNKNPKMSRSVGYSYPSLPPGYQNTTPPGATGV 310 + + E E L P T+ P + PS P + + G Sbjct: 1066 DEAELHEMETEKVSEPECPAL--EPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTA 1123 Query: 311 PPSSLNYPSGPQAFTQTPLGANHLTTSMSGLSLQPEGLRVVNLLQ--------------- 355 P ++ P QTP G+ S + L PE L V ++ Sbjct: 1124 PLDGIDAPGSQPEPGQTP-GSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPC 1182 Query: 356 ERNMLPSTPLKPPVPNL 372 E P P+ P P L Sbjct: 1183 EEQEEPRAPVAPTPPTL 1199 Score = 30.4 bits (67), Expect = 9.6 Identities = 20/52 (38%), Positives = 24/52 (46%), Gaps = 4/52 (7%) Query: 69 PVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAPRMPLPASQNPATTP 120 PV+GQS G+ GSG P S +T + S P P P S P T P Sbjct: 4584 PVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNP----PTPPSSLPPTPP 4631 >gi|31543535 R3H domain containing 1 [Homo sapiens] Length = 1099 Score = 51.6 bits (122), Expect = 4e-06 Identities = 73/307 (23%), Positives = 106/307 (34%), Gaps = 59/307 (19%) Query: 26 SGSPYTNGPVQNALLSSQESVSQGYNFQLPGSYPHPIPAKTLNPVSG----QSNYGGSQG 81 +G P+ N P + ++ + Q Q+PG P+PA P + Q N G SQ Sbjct: 491 TGQPFIN-PDGSPVVYNPPMTQQPVRSQVPGPPQPPLPAPPQQPAANHIFSQDNLG-SQF 548 Query: 82 SGQTLNRPPVA--SNPVTPSLHSGPAPRMPLPASQNPATTPMPSSSFLPEANLPPPLNWQ 139 S +L R P A S+P S + P + P P P PPP Sbjct: 549 SHMSLARQPSADGSDPHAAMFQSTVVLQSPQQSGYIMTAAPPPHPPPPPPPPPPPP---- 604 Query: 140 YNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSGYPSLQNSFIKSGPSVPPLVNPP 199 P QP + Y +SG+P Q + G P +P Sbjct: 605 -------------PLPPGQPVPTAG--------YPASGHPVSQPVLQQQGYIQQP--SPQ 641 Query: 200 LPTTF-QPGAPHGPPPAGGPPPVRALTPLTSSYRDVPQPLFNSAVNQEGITSNTNNGSMV 258 +P + PG H P YR VP +NS +NQ G V Sbjct: 642 MPACYCAPGHYHSSQP---------------QYRPVPSVHYNSHLNQPLPQPAQQTGYQV 686 Query: 259 VHSSYDEIEGGGLLATPQLTNKNPKMSRSVGYS-------YPSLPPGYQNTTPPGATGVP 311 + + +G + PQ + S+G Y S+P YQ + P G+ G+P Sbjct: 687 IPNQQQNYQGIVGVQQPQSQSLVSGQPNSIGNQIQGVVIPYTSVPT-YQVSLPQGSQGIP 745 Query: 312 PSSLNYP 318 + P Sbjct: 746 HQTYQQP 752 Score = 38.9 bits (89), Expect = 0.027 Identities = 85/376 (22%), Positives = 133/376 (35%), Gaps = 55/376 (14%) Query: 8 ASGGAPASLQA--QNGAALASGSPYTNGPVQNALLSSQESVSQGYNFQLPGSYPHPIPAK 65 ASG + S Q+ +N + P+++ ++L + + +V++ +F I Sbjct: 336 ASGRSTNSHQSSTENELKYSEPRPWSSTDSDSSLRNLKPAVTKASSFS-------GISVL 388 Query: 66 TLNPVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGPAPRMPLPASQNPATTPMPSSS 125 T SG S G + + V S+ + S P P L S + A P+ S Sbjct: 389 TRGDSSGSSKSIGRLSKTGSESSGSVGSSTGSLSHIQQPLPGTALSQSSHGAPVVYPTVS 448 Query: 126 FLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSGYPSLQNSF 185 + LN Q PST+ A P S+ N Q +G P F Sbjct: 449 THSSLSFDGGLNGQVASPSTSFFLLPLEAAGIPPG-----SILINPQ---TGQP-----F 495 Query: 186 IKSGPSVPPLVNPPL---PTTFQ-PGAPHGPPPAGGPPPVRALTPLTSSYRDVPQPLFNS 241 I S P + NPP+ P Q PG P P PA PP QP N Sbjct: 496 INPDGS-PVVYNPPMTQQPVRSQVPGPPQPPLPA---PP--------------QQPAANH 537 Query: 242 AVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQLTNKNPKMSRSVGYSYPSLPPGYQN 301 +Q+ + S ++ S+ S D + + + ++P+ S + + P P Sbjct: 538 IFSQDNLGSQFSHMSLARQPSADGSDPHAAMFQSTVVLQSPQQSGYIMTAAPPPHPPPPP 597 Query: 302 TTPPGATGVPPS----SLNYPSGPQAFTQTPLGANHLTTSMSGLSLQPEGLRVVNLLQER 357 PP +PP + YP+ +Q L G QP Sbjct: 598 PPPPPPPPLPPGQPVPTAGYPASGHPVSQPVL-------QQQGYIQQPSPQMPACYCAPG 650 Query: 358 NMLPSTPLKPPVPNLH 373 + S P PVP++H Sbjct: 651 HYHSSQPQYRPVPSVH 666 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.133 0.392 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 47,546,129 Number of Sequences: 37866 Number of extensions: 2662689 Number of successful extensions: 19573 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 90 Number of HSP's successfully gapped in prelim test: 859 Number of HSP's that attempted gapping in prelim test: 13239 Number of HSP's gapped (non-prelim): 4612 length of query: 1093 length of database: 18,247,518 effective HSP length: 113 effective length of query: 980 effective length of database: 13,968,660 effective search space: 13689286800 effective search space used: 13689286800 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.