Search of human proteins with 23510289

Search of human proteins with 23510289

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23510289 sphingosine-1-phosphate phosphotase 2 [Homo
sapiens]
         (399 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23510289 sphingosine-1-phosphate phosphotase 2 [Homo sapiens]      803   0.0  
gi|13540569 sphingosine-1-phosphate phosphatase 1 [Homo sapiens]      278   6e-75
gi|10863975 islet-specific glucose-6-phosphatase-related protein...    40   0.003
gi|30794376 dolichyl pyrophosphate phosphatase 1 isoform a [Homo...    39   0.008
gi|4557599 glucose-6-phosphatase, catalytic subunit [Homo sapiens]     37   0.041
gi|4885325 G protein-coupled receptor 3 [Homo sapiens]                 37   0.041
gi|46409292 dpy-19-like 3 [Homo sapiens]                               36   0.070
gi|118582255 ATP-binding cassette, sub-family C, member 8 [Homo ...    33   0.45 
gi|223029457 phosphatidic acid phosphatase type 2 domain contain...    32   1.0  
gi|167466171 hyaluronan synthase 1 [Homo sapiens]                      31   2.3  
gi|19923559 EMSY protein [Homo sapiens]                                31   2.3  
gi|4557255 adenylate cyclase 7 [Homo sapiens]                          31   2.3  
gi|149944536 ichthyin protein [Homo sapiens]                           30   2.9  
gi|222080049 5-hydroxytryptamine (serotonin) receptor 2B [Homo s...    30   3.8  
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]                    30   3.8  
gi|110832839 ATP-binding cassette, sub-family C, member 9 isofor...    30   5.0  
gi|110832835 ATP-binding cassette, sub-family C, member 9 isofor...    30   5.0  
gi|110832837 ATP-binding cassette, sub-family C, member 9 isofor...    30   5.0  
gi|25121980 dispatched B [Homo sapiens]                                30   5.0  
gi|4758256 eukaryotic translation initiation factor 2, subunit 1...    29   6.6  
gi|126273546 islet-specific glucose-6-phosphatase-related protei...    29   6.6  
gi|18034692 CDW92 antigen [Homo sapiens]                               29   6.6  
gi|66773040 phosphatidic acid phosphatase type 2 domain containi...    29   6.6  
gi|239788462 dihydrouridine synthase 3-like isoform 1 [Homo sapi...    29   8.6  
gi|239582753 MAS-related GPR, member X4 [Homo sapiens]                 29   8.6  
gi|157676334 transmembrane protein 8 (five membrane-spanning dom...    29   8.6  
gi|239788483 dihydrouridine synthase 3-like isoform 2 [Homo sapi...    29   8.6  
gi|27436957 membrane associated guanylate kinase, WW and PDZ dom...    29   8.6  

>gi|23510289 sphingosine-1-phosphate phosphotase 2 [Homo sapiens]
          Length = 399

 Score =  803 bits (2073), Expect = 0.0
 Identities = 399/399 (100%), Positives = 399/399 (100%)

Query: 1   MAELLRSLQDSQLVARFQRRCGLFPAPDEGPRENGADPTERAARVPGVEHLPAANGKGGE 60
           MAELLRSLQDSQLVARFQRRCGLFPAPDEGPRENGADPTERAARVPGVEHLPAANGKGGE
Sbjct: 1   MAELLRSLQDSQLVARFQRRCGLFPAPDEGPRENGADPTERAARVPGVEHLPAANGKGGE 60

Query: 61  APANGLRRAAAPEAYVQKYVVKNYFYYYLFQFSAALGQEVFYITFLPFTHWNIDPYLSRR 120
           APANGLRRAAAPEAYVQKYVVKNYFYYYLFQFSAALGQEVFYITFLPFTHWNIDPYLSRR
Sbjct: 61  APANGLRRAAAPEAYVQKYVVKNYFYYYLFQFSAALGQEVFYITFLPFTHWNIDPYLSRR 120

Query: 121 LIIIWVLVMYIGQVAKDVLKWPRPSSPPVVKLEKRLIAEYGMPSTHAMAATAIAFTLLIS 180
           LIIIWVLVMYIGQVAKDVLKWPRPSSPPVVKLEKRLIAEYGMPSTHAMAATAIAFTLLIS
Sbjct: 121 LIIIWVLVMYIGQVAKDVLKWPRPSSPPVVKLEKRLIAEYGMPSTHAMAATAIAFTLLIS 180

Query: 181 TMDRYQYPFVLGLVMAVVFSTLVCLSRLYTGMHTVLDVLGGVLITALLIVLTYPAWTFID 240
           TMDRYQYPFVLGLVMAVVFSTLVCLSRLYTGMHTVLDVLGGVLITALLIVLTYPAWTFID
Sbjct: 181 TMDRYQYPFVLGLVMAVVFSTLVCLSRLYTGMHTVLDVLGGVLITALLIVLTYPAWTFID 240

Query: 241 CLDSASPLFPVCVIVVPFFLCYNYPVSDYYSPTRADTTTILAAGAGVTIGFWINHFFQLV 300
           CLDSASPLFPVCVIVVPFFLCYNYPVSDYYSPTRADTTTILAAGAGVTIGFWINHFFQLV
Sbjct: 241 CLDSASPLFPVCVIVVPFFLCYNYPVSDYYSPTRADTTTILAAGAGVTIGFWINHFFQLV 300

Query: 301 SKPAESLPVIQNIPPLTTYMLVLGLTKFAVGIVLILLVRQLVQNLSLQVLYSWFKVVTRN 360
           SKPAESLPVIQNIPPLTTYMLVLGLTKFAVGIVLILLVRQLVQNLSLQVLYSWFKVVTRN
Sbjct: 301 SKPAESLPVIQNIPPLTTYMLVLGLTKFAVGIVLILLVRQLVQNLSLQVLYSWFKVVTRN 360

Query: 361 KEARRRLEIEVPYKFVTYTSVGICATTFVPMLHRFLGLP 399
           KEARRRLEIEVPYKFVTYTSVGICATTFVPMLHRFLGLP
Sbjct: 361 KEARRRLEIEVPYKFVTYTSVGICATTFVPMLHRFLGLP 399


>gi|13540569 sphingosine-1-phosphate phosphatase 1 [Homo sapiens]
          Length = 441

 Score =  278 bits (711), Expect = 6e-75
 Identities = 158/436 (36%), Positives = 241/436 (55%), Gaps = 40/436 (9%)

Query: 1   MAELLRSLQDSQLVARFQRRCGLFPAP--------DE---------------------GP 31
           +A+L+  LQD Q VARFQR CG+   P        DE                     GP
Sbjct: 7   LAQLVGRLQDPQKVARFQRLCGVEAPPRRSADRREDEKAEAPLAGDPRLRGRQPGAPGGP 66

Query: 32  RENGADPTERAARVPG-------VEHLPAANGKGGEAPANGLRRAAAPEAYVQKYVVKNY 84
           +  G+D  +  A+  G          L A  G      A  LRR +      Q   V N+
Sbjct: 67  QPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPASPRRAGALRRNSLTGEEGQLARVSNW 126

Query: 85  FYYYLFQFSAALGQEVFYITFLPFTHWNIDPYLSRRLIIIWVLVMYIGQVAKDVLKWPRP 144
             Y LF F   LG E+FYI F PF  WN+DP + RRL++IWVLVMY+GQ  KD+++WPRP
Sbjct: 127 PLYCLFCFGTELGNELFYILFFPFWIWNLDPLVGRRLVVIWVLVMYLGQCTKDIIRWPRP 186

Query: 145 SSPPVVKLEKRLIAEYGMPSTHAMAATAIAFTLLISTMDRYQYPFVLGLVMAVVFSTLVC 204
           +SPPVVKLE    +EY MPSTHAM+ TAI  ++++ T  R+QYP + GL++   + +LVC
Sbjct: 187 ASPPVVKLEVFYNSEYSMPSTHAMSGTAIPISMVLLTYGRWQYPLIYGLILIPCWCSLVC 246

Query: 205 LSRLYTGMHTVLDVLGGVLITALLIVLTYPAWTFIDCLDSASPLFPVCVIVVPFFLCYNY 264
           LSR+Y GMH++LD++ G L T L++ + YP    ID  +      P  +I +   L    
Sbjct: 247 LSRIYMGMHSILDIIAGFLYTILILAVFYPFVDLIDNFNQTHKYAPFIIIGLHLALGIFS 306

Query: 265 PVSDYYSPTRADTTTILAAGAGVTIGFWINHFFQLVSKPA-ESLPVIQNIPPLTTYMLVL 323
              D +S +R DT  IL +GAG+  G  + +   LV  P+ ++LP+    PP+T  +   
Sbjct: 307 FTLDTWSTSRGDTAEILGSGAGIACGSHVTYNMGLVLDPSLDTLPLAG--PPITVTLFGK 364

Query: 324 GLTKFAVGIVLILLVRQLVQNLSLQVLYSWFKVVTRN-KEARRRLEIEVPYKFVTYTSVG 382
            + +  +G+V +L++R +++ +++ +    F +   + ++AR+ +E+E+PY+++TY  VG
Sbjct: 365 AILRILIGMVFVLIIRDVMKKITIPLACKIFNIPCDDIRKARQHMEVELPYRYITYGMVG 424

Query: 383 ICATTFVPMLHRFLGL 398
              T FVP +  F+G+
Sbjct: 425 FSITFFVPYIFFFIGI 440


>gi|10863975 islet-specific glucose-6-phosphatase-related protein
           isoform 1 [Homo sapiens]
          Length = 355

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 38/165 (23%), Positives = 73/165 (44%), Gaps = 33/165 (20%)

Query: 82  KNYFYYYL---FQFSAALGQEVFYITFLPFTHWNIDPYLSRRLIIIWVLVMYIGQV-AKD 137
           +N F+ Y    FQF+  +G ++ ++         I  +L+  LI  W+L  +      ++
Sbjct: 36  RNIFFIYFPLCFQFNQTVGTKMIWVAV-------IGDWLN--LIFKWILFGHRPYWWVQE 86

Query: 138 VLKWPRPSSPPVVKLEKRLIAEYGMPSTHAMAATAIAFTLLIS--------------TMD 183
              +P  SSP + +         G PS HAM A+ + + ++ +              T+ 
Sbjct: 87  TQIYPNHSSPCLEQFPTTCETGPGSPSGHAMGASCVWYVMVTAALSHTVCGMDKFSITLH 146

Query: 184 RYQYPFVLGLVMAVVFSTLVCLSRLYTGMH----TVLDVLGGVLI 224
           R  + F+  +   +  S  VC+SR++   H     +L V+GG+L+
Sbjct: 147 RLTWSFLWSVFWLIQIS--VCISRVFIATHFPHQVILGVIGGMLV 189


>gi|30794376 dolichyl pyrophosphate phosphatase 1 isoform a [Homo
           sapiens]
          Length = 238

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 40/133 (30%), Positives = 62/133 (46%), Gaps = 25/133 (18%)

Query: 131 IGQVAKDVLKWPRPSSPPVVKLEKRLIAEYGMPSTHAMAA---TAIAFTLLISTMDR--- 184
           +  + K+V++ PRP   P   +  +    YGMPS+H+      +  +F  L   M +   
Sbjct: 72  VNWLIKNVIQEPRPCGGPHTAVGTK----YGMPSSHSQFMWFFSVYSFLFLYLRMHQTNN 127

Query: 185 -------YQYPFVLGLVMAVVFSTLVCLSRLYTGMHTVLDVLGGVLITALLIVLTYPAWT 237
                  +++   LGL +AV F  LV  SR+Y   HT   VL G +   L+ +    AW 
Sbjct: 128 ARFLDLLWRHVLSLGL-LAVAF--LVSYSRVYLLYHTWSQVLYGGIAGGLMAI----AW- 179

Query: 238 FIDCLDSASPLFP 250
           FI   +  +PLFP
Sbjct: 180 FIFTQEVLTPLFP 192


>gi|4557599 glucose-6-phosphatase, catalytic subunit [Homo sapiens]
          Length = 357

 Score = 36.6 bits (83), Expect = 0.041
 Identities = 37/149 (24%), Positives = 64/149 (42%), Gaps = 25/149 (16%)

Query: 98  QEVFYITFLPFTHWNIDPYLSRRLIIIWVLVMYIGQVAKDVLKWPRP------------- 144
           +  FY+ F  + H  +   +  +L+ + V+  ++  V K +L   RP             
Sbjct: 40  RNAFYVLFPIWFH--LQEAVGIKLLWVAVIGDWLNLVFKWILFGQRPYWWVLDTDYYSNT 97

Query: 145 SSPPVVKLEKRLIAEYGMPSTHAMAATAIAFTLLISTMDRYQ------YPF-VLGLVMAV 197
           S P + +         G PS HAM    + + ++ ST+  +Q      Y F  L +++ +
Sbjct: 98  SVPLIKQFPVTCETGPGSPSGHAMGTAGVYYVMVTSTLSIFQGKIKPTYRFRCLNVILWL 157

Query: 198 VFSTL---VCLSRLYTGMHTVLDVLGGVL 223
            F  +   VCLSR+Y   H    V+ GVL
Sbjct: 158 GFWAVQLNVCLSRIYLAAHFPHQVVAGVL 186


>gi|4885325 G protein-coupled receptor 3 [Homo sapiens]
          Length = 330

 Score = 36.6 bits (83), Expect = 0.041
 Identities = 33/108 (30%), Positives = 51/108 (47%), Gaps = 16/108 (14%)

Query: 167 AMAATAIAFTLLISTMDRYQYPFVLGLVMAVVFSTLVCLSRLYTGMHTVLDVLGGVLITA 226
           AMA TA   +LL  T+DRY     L L  A+ + +   ++R Y  +     V GG L   
Sbjct: 117 AMAFTASIGSLLAITVDRY-----LSLYNALTYYSETTVTRTYVMLAL---VWGGALGLG 168

Query: 227 LLIVLTYPAWTFIDCLDSASPLFP-----VCVIVVPFFLCYNYPVSDY 269
           LL VL   AW  +D L +   ++P     + V+ + FF+ +   +  Y
Sbjct: 169 LLPVL---AWNCLDGLTTCGVVYPLSKNHLVVLAIAFFMVFGIMLQLY 213


>gi|46409292 dpy-19-like 3 [Homo sapiens]
          Length = 716

 Score = 35.8 bits (81), Expect = 0.070
 Identities = 41/160 (25%), Positives = 66/160 (41%), Gaps = 13/160 (8%)

Query: 76  VQKYVVKNYFYYYLFQFSAALGQEVFYITFLPFTHWNID-PYLSRRLIIIWVLVMYIGQV 134
           +QKY+   YFY Y        G +  Y+T L  T W +   +LS  L   W +   I   
Sbjct: 149 IQKYLEPVYFYIY-----TLFGLQAIYVTALYITSWLLSGTWLSGLLAAFWYVTNRIDTT 203

Query: 135 AKDVLKWPRPS-SPPVVKLEKRLIAEYGMPSTHAMAATAIAFTLLISTM---DRYQYPFV 190
             +     R + + P   ++   I  +  P+   ++       + IST      +Q+   
Sbjct: 204 RVEFTIPLRENWALPFFAIQIAAITYFLRPNLQPLSERLTLLAIFISTFLFSLTWQFNQF 263

Query: 191 LGLVMAVVFSTLVCLSRLYTGMHTVLDVLGGVLITALLIV 230
           + L+ A+V  TL  L  L     T    L G+ IT+LL+V
Sbjct: 264 MMLMQALVLFTLDSLDMLPAVKAT---WLYGIQITSLLLV 300


>gi|118582255 ATP-binding cassette, sub-family C, member 8 [Homo
           sapiens]
          Length = 1581

 Score = 33.1 bits (74), Expect = 0.45
 Identities = 15/52 (28%), Positives = 26/52 (50%)

Query: 340 QLVQNLSLQVLYSWFKVVTRNKEARRRLEIEVPYKFVTYTSVGICATTFVPM 391
           ++++ + L  LY+W  +     E  RR E+     F  YTS+ I   T +P+
Sbjct: 501 EMLRGIKLLKLYAWENIFRTRVETTRRKEMTSLRAFAIYTSISIFMNTAIPI 552


>gi|223029457 phosphatidic acid phosphatase type 2 domain containing
           3 [Homo sapiens]
          Length = 271

 Score = 32.0 bits (71), Expect = 1.0
 Identities = 34/124 (27%), Positives = 55/124 (44%), Gaps = 14/124 (11%)

Query: 117 LSRRLIIIWVLVMYIGQVAKDVLK-WPRPSSPPVVKLEKRLIAEYGMPSTHAMAATAIAF 175
           L   L+ + + +M +  V K + +  P  +SP +  L+   +  Y  P+ HA  A  ++ 
Sbjct: 145 LMNLLLALLLDIMTVAGVQKLIKRRGPYETSPSL--LDYLTMDIYAFPAGHASRAAMVSK 202

Query: 176 TLLISTMDRYQYPFVLGL---VMAVVFSTLVCLSRLYTGMHTVLDVLGGVLITALLIVLT 232
             L           VL +   V+ V+++  V LSR+  G H V DVL G +I  L   L 
Sbjct: 203 FFLSH--------LVLAVPLRVLLVLWALCVGLSRVMIGRHHVTDVLSGFVIGYLQFRLV 254

Query: 233 YPAW 236
              W
Sbjct: 255 ELVW 258


>gi|167466171 hyaluronan synthase 1 [Homo sapiens]
          Length = 578

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 12/27 (44%), Positives = 18/27 (66%)

Query: 267 SDYYSPTRADTTTILAAGAGVTIGFWI 293
           +D+  P+RA     LAAGAG  +G+W+
Sbjct: 527 ADWSGPSRAAEAYHLAAGAGAYVGYWV 553


>gi|19923559 EMSY protein [Homo sapiens]
          Length = 1322

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 16/45 (35%), Positives = 24/45 (53%), Gaps = 1/45 (2%)

Query: 144 PSSPPVVKLEKRLIAEYGMPSTHAMAATAIAFTLLISTMDRYQYP 188
           P SP +  +E  L+AEY + +      T +AF LL+S   + Q P
Sbjct: 819 PESPSIAVVESELVAEY-ITTERTDEGTEVAFPLLVSHRSQPQQP 862


>gi|4557255 adenylate cyclase 7 [Homo sapiens]
          Length = 1080

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 35/116 (30%), Positives = 49/116 (42%), Gaps = 15/116 (12%)

Query: 156 LIAEYGMPSTHA--------MAATAIAFTLLI--STMDRYQYPFVLG---LVMAV--VFS 200
           L  +Y + S H         +AATA    ++I  S  D  ++  +LG   LV+AV    S
Sbjct: 21  LYEKYQLTSQHGPLLLTLLLVAATACVALIIIAFSQGDPSRHQAILGMAFLVLAVFAALS 80

Query: 201 TLVCLSRLYTGMHTVLDVLGGVLITALLIVLTYPAWTFIDCLDSASPLFPVCVIVV 256
            L+ +  L       L +L    + AL  VL + AWT   C     P F   V VV
Sbjct: 81  VLMYVECLLRRWLRALALLTWACLVALGYVLVFDAWTKAACAWEQVPFFLFIVFVV 136


>gi|149944536 ichthyin protein [Homo sapiens]
          Length = 466

 Score = 30.4 bits (67), Expect = 2.9
 Identities = 28/132 (21%), Positives = 55/132 (41%), Gaps = 28/132 (21%)

Query: 184 RYQYPFVLGLVMAVVFSTLVCLSRLYTGMHTVLDVLGGVLITALLIVLTYPAWTFIDCLD 243
           R+  P++L L++A+  ST V        ++  LD+      T+L+  + Y          
Sbjct: 322 RHPLPYILSLILALSLSTQVNF------LNRALDIFN----TSLVFPIYY---------- 361

Query: 244 SASPLFPVCVIVVPFFLCYNYPVSDYYSPTRADTTTILAAGAGVTIGFWINHFFQLVSKP 303
               +F   V+V    + +     ++YS +  D    L+    + +G ++ H F+ +   
Sbjct: 362 ----VFFTTVVVTSSIILFK----EWYSMSAVDIAGTLSGFVTIILGVFMLHAFKDLDIS 413

Query: 304 AESLPVIQNIPP 315
             SLP +   PP
Sbjct: 414 CASLPHMHKNPP 425


>gi|222080049 5-hydroxytryptamine (serotonin) receptor 2B [Homo
           sapiens]
          Length = 481

 Score = 30.0 bits (66), Expect = 3.8
 Identities = 19/79 (24%), Positives = 37/79 (46%), Gaps = 2/79 (2%)

Query: 199 FSTLVCLSRLYTGMHTVLDVLGGVLITAL--LIVLTYPAWTFIDCLDSASPLFPVCVIVV 256
           F   + ++ L  G+  +   L  ++  A+  L ++  PAW F+D L S + +  +C I V
Sbjct: 92  FLMSLAVADLLVGLFVMPIALLTIMFEAMWPLPLVLCPAWLFLDVLFSTASIMHLCAISV 151

Query: 257 PFFLCYNYPVSDYYSPTRA 275
             ++    P+      +RA
Sbjct: 152 DRYIAIKKPIQANQYNSRA 170


>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
          Length = 1489

 Score = 30.0 bits (66), Expect = 3.8
 Identities = 16/41 (39%), Positives = 22/41 (53%), Gaps = 1/41 (2%)

Query: 26  APDEGPRENGADPTERAARVPGVEHLPAANGKGGEAPANGL 66
           A + GPR+ G  P  R  +VPG+   P   G G +AP+  L
Sbjct: 911 ARETGPRKAGRGPGNRE-KVPGLNRDPTVLGNGKQAPSLSL 950


>gi|110832839 ATP-binding cassette, sub-family C, member 9 isoform
           SUR2A-delta-14 [Homo sapiens]
          Length = 1513

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 13/52 (25%), Positives = 26/52 (50%)

Query: 340 QLVQNLSLQVLYSWFKVVTRNKEARRRLEIEVPYKFVTYTSVGICATTFVPM 391
           ++++ + L  LY+W  +  ++ E  R  E+     F  YTS+ I     +P+
Sbjct: 497 EILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPI 548


>gi|110832835 ATP-binding cassette, sub-family C, member 9 isoform
           SUR2A [Homo sapiens]
          Length = 1549

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 13/52 (25%), Positives = 26/52 (50%)

Query: 340 QLVQNLSLQVLYSWFKVVTRNKEARRRLEIEVPYKFVTYTSVGICATTFVPM 391
           ++++ + L  LY+W  +  ++ E  R  E+     F  YTS+ I     +P+
Sbjct: 497 EILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPI 548


>gi|110832837 ATP-binding cassette, sub-family C, member 9 isoform
           SUR2B [Homo sapiens]
          Length = 1549

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 13/52 (25%), Positives = 26/52 (50%)

Query: 340 QLVQNLSLQVLYSWFKVVTRNKEARRRLEIEVPYKFVTYTSVGICATTFVPM 391
           ++++ + L  LY+W  +  ++ E  R  E+     F  YTS+ I     +P+
Sbjct: 497 EILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPI 548


>gi|25121980 dispatched B [Homo sapiens]
          Length = 1401

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 7/84 (8%)

Query: 190  VLGLVMAVVFSTLVCLS-RLYTGMHTVLDVLGGVLITALLIVLTYPAWTFIDCLDSASPL 248
            VLGL +A+ F+TL+  +  +   + +V  V G VL+T  L+VL    W     L++A  L
Sbjct: 967  VLGLALALAFATLLLGTWNVPLSLFSVAAVAGTVLLTVGLLVLL--EWQ----LNTAEAL 1020

Query: 249  FPVCVIVVPFFLCYNYPVSDYYSP 272
            F    + +      NY +S +  P
Sbjct: 1021 FLSASVGLSVDFTVNYCISYHLCP 1044


>gi|4758256 eukaryotic translation initiation factor 2, subunit 1
           alpha, 35kDa [Homo sapiens]
          Length = 315

 Score = 29.3 bits (64), Expect = 6.6
 Identities = 20/74 (27%), Positives = 30/74 (40%)

Query: 1   MAELLRSLQDSQLVARFQRRCGLFPAPDEGPRENGADPTERAARVPGVEHLPAANGKGGE 60
           +AE+L   +D QL + FQR   +F    + P     D  + A   P +      N    E
Sbjct: 115 VAEVLEYTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDERE 174

Query: 61  APANGLRRAAAPEA 74
              N + R   P+A
Sbjct: 175 VLINNINRRLTPQA 188


>gi|126273546 islet-specific glucose-6-phosphatase-related protein
           isoform 2 [Homo sapiens]
          Length = 154

 Score = 29.3 bits (64), Expect = 6.6
 Identities = 24/105 (22%), Positives = 48/105 (45%), Gaps = 13/105 (12%)

Query: 82  KNYFYYYL---FQFSAALGQEVFYITFLPFTHWNIDPYLSRRLIIIWVLVMYIGQV-AKD 137
           +N F+ Y    FQF+  +G ++ ++         I  +L+  LI  W+L  +      ++
Sbjct: 36  RNIFFIYFPLCFQFNQTVGTKMIWVAV-------IGDWLN--LIFKWILFGHRPYWWVQE 86

Query: 138 VLKWPRPSSPPVVKLEKRLIAEYGMPSTHAMAATAIAFTLLISTM 182
              +P  SSP + +         G PS HAM A+ + + ++ + +
Sbjct: 87  TQIYPNHSSPCLEQFPTTCETGPGSPSGHAMGASCVWYVMVTAAL 131


>gi|18034692 CDW92 antigen [Homo sapiens]
          Length = 657

 Score = 29.3 bits (64), Expect = 6.6
 Identities = 40/150 (26%), Positives = 61/150 (40%), Gaps = 30/150 (20%)

Query: 116 YLSRRLIIIWVLVMYIGQVAKDVLKW-----PRPSSPPVVKLEKRLIAEYGMPSTHAMAA 170
           Y+SR L+ I  +++ +G +    + W      R S    V  E+  IAE  + +    A 
Sbjct: 235 YISRVLVWILTILVILGSLGGTGVLWWLYAKQRRSPKETVTPEQLQIAEDNLRALLIYAI 294

Query: 171 TAIAFTLLISTMDRYQYPFVLGLVMAVVFSTLVCLSRLYTGMHTVLDVLGGVLITALLIV 230
           +A  FT+++         F++ LVM    +  + L            V G V I   L+V
Sbjct: 295 SATVFTVIL---------FLIMLVMRKRVALTIAL----------FHVAGKVFIHLPLLV 335

Query: 231 LTYPAWTFIDCLDSASPLFPVCVIVVPFFL 260
              P WTF      A  LF V  I+   FL
Sbjct: 336 FQ-PFWTFF-----ALVLFWVYWIMTLLFL 359


>gi|66773040 phosphatidic acid phosphatase type 2 domain containing
           2 [Homo sapiens]
          Length = 295

 Score = 29.3 bits (64), Expect = 6.6
 Identities = 25/107 (23%), Positives = 49/107 (45%), Gaps = 11/107 (10%)

Query: 121 LIIIWVLVMYIGQVAKDVLKWPRPSSPPVVKLEKRLIAEYGMPSTHAMAATAIAFTLLIS 180
           L+   +L + +  + K +++  RP+   +       + +Y  PS HA  A  ++  +L  
Sbjct: 169 LLFALLLDLLLVALIKGLVRRRRPAHNQMDMFVTLSVDKYSFPSGHATRAALMSRFILNH 228

Query: 181 TMDRYQYPFVLGL---VMAVVFSTLVCLSRLYTGMHTVLDVLGGVLI 224
                    VL +   V+ V+++ ++ LSR+  G H V DV  G  +
Sbjct: 229 --------LVLAIPLRVLVVLWAFVLGLSRVMLGRHNVTDVAFGFFL 267


>gi|239788462 dihydrouridine synthase 3-like isoform 1 [Homo
          sapiens]
          Length = 650

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 20/53 (37%), Positives = 23/53 (43%), Gaps = 5/53 (9%)

Query: 47 GVEHLPAANGKGGEAPANGLRRAAAPEAYVQKYVVKNYFYYYLFQFSAALGQE 99
          G    P  NG GG++ A  L R  AP    Q    K  F+    QF  A GQE
Sbjct: 4  GTAEAPLENGGGGDSGAGALERGVAP-IKRQYLTTKEQFH----QFLEAKGQE 51


>gi|239582753 MAS-related GPR, member X4 [Homo sapiens]
          Length = 322

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 19/98 (19%)

Query: 177 LLISTMDRYQYPFVLGLVMAVVFSTLVCLSRLYTGMH-----TVLDVLGGVLITALLIVL 231
           +L+S M    +P+  GL M    ST  CLS L+   +     T L  +  VL+  L ++ 
Sbjct: 97  ILVSVMT---FPYFTGLSMLSAISTERCLSVLWPIWYRCRRPTHLSAVVCVLLWGLSLLF 153

Query: 232 TYPAWTFIDCLDS--------ASPLFPVCVIVVPFFLC 261
           +   W F D L S         S   PV  ++   FLC
Sbjct: 154 SMLEWRFCDFLFSGADSSWCETSDFIPVAWLI---FLC 188


>gi|157676334 transmembrane protein 8 (five membrane-spanning
           domains) [Homo sapiens]
          Length = 771

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 20/63 (31%), Positives = 33/63 (52%), Gaps = 1/63 (1%)

Query: 177 LLISTMDRYQYPFVLGLVMAVVFSTLVCLSRLYTGMHTVLDVLGGVLITALLIVLTYPAW 236
           L I + D  QY   LG   A ++ T++C++RL T +  VL +LG ++I   L +     W
Sbjct: 598 LCILSYDTLQYCDFLGSG-AAIWVTILCMARLKTVLKYVLFLLGTLVIAMSLQLDRRGMW 656

Query: 237 TFI 239
             +
Sbjct: 657 NML 659


>gi|239788483 dihydrouridine synthase 3-like isoform 2 [Homo
          sapiens]
          Length = 408

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 20/53 (37%), Positives = 23/53 (43%), Gaps = 5/53 (9%)

Query: 47 GVEHLPAANGKGGEAPANGLRRAAAPEAYVQKYVVKNYFYYYLFQFSAALGQE 99
          G    P  NG GG++ A  L R  AP    Q    K  F+    QF  A GQE
Sbjct: 4  GTAEAPLENGGGGDSGAGALERGVAP-IKRQYLTTKEQFH----QFLEAKGQE 51


>gi|27436957 membrane associated guanylate kinase, WW and PDZ domain
            containing 2 [Homo sapiens]
          Length = 1455

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 17/48 (35%), Positives = 21/48 (43%), Gaps = 6/48 (12%)

Query: 20   RCGLFPAPDEGPRENGADPTERAA------RVPGVEHLPAANGKGGEA 61
            R G    P  GPR  G  P  +AA      +VPG + LP+    G  A
Sbjct: 1405 RAGARAGPRPGPRPPGGAPARKAAVAPGPWKVPGSDKLPSVLKPGASA 1452


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.141    0.439 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,853,870
Number of Sequences: 37866
Number of extensions: 665407
Number of successful extensions: 2611
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 2587
Number of HSP's gapped (non-prelim): 35
length of query: 399
length of database: 18,247,518
effective HSP length: 104
effective length of query: 295
effective length of database: 14,309,454
effective search space: 4221288930
effective search space used: 4221288930
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.