Guide to the Human Genome
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Search of human proteins with 23397500

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23397500 F-box protein 39 [Homo sapiens]
         (442 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23397500 F-box protein 39 [Homo sapiens]                           902   0.0  
gi|16306584 F-box and leucine-rich repeat protein 3 [Homo sapiens]     47   3e-05
gi|148922963 F-box and leucine-rich repeat protein 21 [Homo sapi...    42   0.001
gi|8923179 F-box and leucine-rich repeat protein 12 [Homo sapiens]     39   0.007
gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens]    37   0.047
gi|42558258 F-box protein 33 [Homo sapiens]                            36   0.080
gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens]      36   0.080
gi|24308129 F-box and WD repeat domain containing 5 [Homo sapiens]     35   0.14 
gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens]             35   0.18 
gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens]             35   0.18 
gi|30089922 F-box only protein 11 isoform 3 [Homo sapiens]             35   0.18 
gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo ...    33   0.52 
gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo ...    33   0.52 
gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapi...    32   0.88 
gi|22547146 F-box and leucine-rich repeat protein 8 [Homo sapiens]     32   1.2  
gi|67003566 F-box protein 48 [Homo sapiens]                            32   1.5  
gi|33359221 dyslexia susceptibility 2-like [Homo sapiens]              31   2.0  
gi|110624785 NACHT, leucine rich repeat and PYD containing 13 [H...    30   3.4  
gi|52426787 oligodendrocyte myelin glycoprotein [Homo sapiens]         30   4.4  
gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]     30   4.4  
gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [H...    29   7.5  
gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [H...    29   7.5  
gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens]    29   7.5  
gi|208609985 SH2 domain containing 3A [Homo sapiens]                   29   9.8  
gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2 [H...    29   9.8  
gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [H...    29   9.8  

>gi|23397500 F-box protein 39 [Homo sapiens]
          Length = 442

 Score =  902 bits (2330), Expect = 0.0
 Identities = 442/442 (100%), Positives = 442/442 (100%)

Query: 1   MDEESELIQPQDQSCWAFLPDLCLCRVFWWLGDRDRSRAALVCRKWNQMMYSAELWRYRT 60
           MDEESELIQPQDQSCWAFLPDLCLCRVFWWLGDRDRSRAALVCRKWNQMMYSAELWRYRT
Sbjct: 1   MDEESELIQPQDQSCWAFLPDLCLCRVFWWLGDRDRSRAALVCRKWNQMMYSAELWRYRT 60

Query: 61  ITFSGRPSRVHASEVESAVWYVKKFGRYLEHLEVKFMNPYNAVLTKKFQVTMRGLLSCLS 120
           ITFSGRPSRVHASEVESAVWYVKKFGRYLEHLEVKFMNPYNAVLTKKFQVTMRGLLSCLS
Sbjct: 61  ITFSGRPSRVHASEVESAVWYVKKFGRYLEHLEVKFMNPYNAVLTKKFQVTMRGLLSCLS 120

Query: 121 KSNNRLKSLSIQYLELDRLVWRNSIRSSFISSLSFFLKKMGKRLDYLNLKGARLTVEQGC 180
           KSNNRLKSLSIQYLELDRLVWRNSIRSSFISSLSFFLKKMGKRLDYLNLKGARLTVEQGC
Sbjct: 121 KSNNRLKSLSIQYLELDRLVWRNSIRSSFISSLSFFLKKMGKRLDYLNLKGARLTVEQGC 180

Query: 181 QILDSLSYMRNENVISELNIEDYFSHHLAVYNSPQFKKTMSTFHNLVSLNLNYNCISDEL 240
           QILDSLSYMRNENVISELNIEDYFSHHLAVYNSPQFKKTMSTFHNLVSLNLNYNCISDEL
Sbjct: 181 QILDSLSYMRNENVISELNIEDYFSHHLAVYNSPQFKKTMSTFHNLVSLNLNYNCISDEL 240

Query: 241 LENLCENASTLRTINIKCHVHDPHGQVIWGMSWAKLARQATNLKVNFFFERIMKYERLAR 300
           LENLCENASTLRTINIKCHVHDPHGQVIWGMSWAKLARQATNLKVNFFFERIMKYERLAR
Sbjct: 241 LENLCENASTLRTINIKCHVHDPHGQVIWGMSWAKLARQATNLKVNFFFERIMKYERLAR 300

Query: 301 ILLQEIPIRSISLRSCYFSDPDCSMRPTLIDLLPTFRHTLQKLTCEFNNNHESLDEELHL 360
           ILLQEIPIRSISLRSCYFSDPDCSMRPTLIDLLPTFRHTLQKLTCEFNNNHESLDEELHL
Sbjct: 301 ILLQEIPIRSISLRSCYFSDPDCSMRPTLIDLLPTFRHTLQKLTCEFNNNHESLDEELHL 360

Query: 361 LIISCRKLFYFKIWAFLDVSFVERILKSQKERQCALRVFKARIYTNRYETNEEDKTLQEI 420
           LIISCRKLFYFKIWAFLDVSFVERILKSQKERQCALRVFKARIYTNRYETNEEDKTLQEI
Sbjct: 361 LIISCRKLFYFKIWAFLDVSFVERILKSQKERQCALRVFKARIYTNRYETNEEDKTLQEI 420

Query: 421 YRKYRKLIESELSYFVIVYSVM 442
           YRKYRKLIESELSYFVIVYSVM
Sbjct: 421 YRKYRKLIESELSYFVIVYSVM 442


>gi|16306584 F-box and leucine-rich repeat protein 3 [Homo sapiens]
          Length = 428

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 69/298 (23%), Positives = 122/298 (40%), Gaps = 36/298 (12%)

Query: 13  QSC-WAFLPDLCLCRVFWWLGDRDRSRAALVCRKWNQMMYSAELWR-YRTITFSGRPSRV 70
           Q+C W  L    + +VF +L   DR+ A+ VCR WNQ+ +  +LWR +         S +
Sbjct: 32  QTCDWGNLLQDIILQVFKYLPLLDRAHASQVCRNWNQVFHMPDLWRCFEFELNQPATSYL 91

Query: 71  HASEVESAVWYVKKFGRYLEHLEVKFMNPYNAVLTKKFQVTMRGLLSCLSKSNNRLKSLS 130
            A+  E     +K+   +L+++  K  +   +   +     +  L++C  K+   + +  
Sbjct: 92  KATHPELIKQIIKRHSNHLQYVSFKVDSSKES--AEAACDILSQLVNCSLKTLGLISTAR 149

Query: 131 IQYLELDRLVWRNSIRSSFISSLSF-FLKKMGKRLDYLNLKGARLTVEQGCQILDSLSYM 189
             +++L +  + +++   F++S S   LK     +D  +LK          ++L  +S  
Sbjct: 150 PSFMDLPKSHFISALTVVFVNSKSLSSLKIDDTPVDDPSLKVLVANNSDTLKLL-KMSSC 208

Query: 190 RNENVISELNIEDYFSHHLAVYNSPQFKKTMSTFHNLVSLNLNYNCISDELLENL-CENA 248
            + +    L + D                     H L  L LNY+ +SDELL  L  E  
Sbjct: 209 PHVSPAGILCVAD-------------------QCHGLRELALNYHLLSDELLLALSSEKH 249

Query: 249 STLRTINIKCHVHDP---HGQVIWGMSWAKLARQA--TNLKVNFF-----FERIMKYE 296
             L  + I     +P   H   I   SW    R +   NL + FF     F+   +YE
Sbjct: 250 VRLEHLRIDVVSENPGQTHFHTIQKSSWDAFIRHSPKVNLVMYFFLYEEEFDPFFRYE 307


>gi|148922963 F-box and leucine-rich repeat protein 21 [Homo
          sapiens]
          Length = 434

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 16/42 (38%), Positives = 28/42 (66%)

Query: 16 WAFLPDLCLCRVFWWLGDRDRSRAALVCRKWNQMMYSAELWR 57
          W  LP   + ++F +L   DR+ A+ VCR+WN++ + ++LWR
Sbjct: 42 WGSLPHHVVLQIFQYLPLLDRACASSVCRRWNEVFHISDLWR 83


>gi|8923179 F-box and leucine-rich repeat protein 12 [Homo
          sapiens]
          Length = 326

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 19/50 (38%), Positives = 30/50 (60%), Gaps = 1/50 (2%)

Query: 19 LPDLCLCRVFWWLGDRDRSRAALVCRKWNQMMYSAELWRYRTIT-FSGRP 67
          LPD  L  +F +L  RDR R + VC +W +++    LWR+  +T ++ RP
Sbjct: 7  LPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLYTMRP 56


>gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens]
          Length = 418

 Score = 36.6 bits (83), Expect = 0.047
 Identities = 42/192 (21%), Positives = 79/192 (41%), Gaps = 12/192 (6%)

Query: 20  PDLCLCRVFWWLGDRDRSRAALVCRKWNQMMYSAELWRYRTITFSGRPSRVHASEVESAV 79
           P+L L  +F +L  RD+ RAA VC  W    Y   +WR       G  +++H      ++
Sbjct: 10  PEL-LAMIFGYLDVRDKGRAAQVCTAWRDAAYHKSVWR-------GVEAKLHLRRANPSL 61

Query: 80  WYVKKFGRYLEHLEV-KFMNPYNAVLTKKFQVTMRGLLSCLSKSNNRLKSLSIQYLELDR 138
            +     R +  +++       + V+     +    L  C + ++N L    +Q +   R
Sbjct: 62  -FPSLQARGIRRVQILSLRRSLSYVIQGMANIESLNLSGCYNLTDNGLGHAFVQEIGSLR 120

Query: 139 LVWRNSIRSSFISSLSFFLKKMGKRLDYLNLKGARLTVEQGCQILD-SLSYMRNENVISE 197
            +  +  +    SSL    + + K L+ L L G       G  ++   L  +++ N+ S 
Sbjct: 121 ALNLSLCKQITDSSLGRIAQYL-KGLEVLELGGCSNITNTGLLLIAWGLQRLKSLNLRSC 179

Query: 198 LNIEDYFSHHLA 209
            ++ D    HLA
Sbjct: 180 RHLSDVGIGHLA 191


>gi|42558258 F-box protein 33 [Homo sapiens]
          Length = 555

 Score = 35.8 bits (81), Expect = 0.080
 Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 17  AFLPDLCLCRVFWWLGDRDRSRAALVCRKWNQMMYSAELWRYRTITFSGRPSRVHASEVE 76
           A LP   +  +F +L   DR RA+  C  W + ++   LW    I       RV  +E  
Sbjct: 69  ASLPSELIVHIFSFLPAPDRLRASASCSHWRECLFYPALWPQLRICL-----RVSPAEQP 123

Query: 77  SAVWYVKKFGRYLEHLEVKF 96
              + ++K G ++  L V+F
Sbjct: 124 RLEFLMRKCGWFVRELRVEF 143


>gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens]
          Length = 491

 Score = 35.8 bits (81), Expect = 0.080
 Identities = 18/52 (34%), Positives = 26/52 (50%), Gaps = 2/52 (3%)

Query: 19  LPDLCLCRVFWWLGDRDRSRAALVCRKWNQMMYSAELWRYRTITFSGRPSRV 70
           LPD  + ++F +L      R A VCR+W  + +   LW  RTI  +G    V
Sbjct: 117 LPDHSMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLW--RTIRLTGETINV 166


>gi|24308129 F-box and WD repeat domain containing 5 [Homo
          sapiens]
          Length = 566

 Score = 35.0 bits (79), Expect = 0.14
 Identities = 17/46 (36%), Positives = 23/46 (50%)

Query: 12 DQSCWAFLPDLCLCRVFWWLGDRDRSRAALVCRKWNQMMYSAELWR 57
          D+     LPD  + ++F  LG  D   A LVCR+W  +     LWR
Sbjct: 2  DEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWR 47


>gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens]
          Length = 843

 Score = 34.7 bits (78), Expect = 0.18
 Identities = 15/48 (31%), Positives = 29/48 (60%)

Query: 10  PQDQSCWAFLPDLCLCRVFWWLGDRDRSRAALVCRKWNQMMYSAELWR 57
           P +Q     LPD  + ++F +L ++D  RAA VC++++++     LW+
Sbjct: 66  PAEQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWK 113


>gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens]
          Length = 686

 Score = 34.7 bits (78), Expect = 0.18
 Identities = 15/48 (31%), Positives = 29/48 (60%)

Query: 10  PQDQSCWAFLPDLCLCRVFWWLGDRDRSRAALVCRKWNQMMYSAELWR 57
           P +Q     LPD  + ++F +L ++D  RAA VC++++++     LW+
Sbjct: 66  PAEQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWK 113


>gi|30089922 F-box only protein 11 isoform 3 [Homo sapiens]
          Length = 585

 Score = 34.7 bits (78), Expect = 0.18
 Identities = 15/48 (31%), Positives = 29/48 (60%)

Query: 10  PQDQSCWAFLPDLCLCRVFWWLGDRDRSRAALVCRKWNQMMYSAELWR 57
           P +Q     LPD  + ++F +L ++D  RAA VC++++++     LW+
Sbjct: 66  PAEQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWK 113


>gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo
           sapiens]
          Length = 424

 Score = 33.1 bits (74), Expect = 0.52
 Identities = 45/208 (21%), Positives = 80/208 (38%), Gaps = 31/208 (14%)

Query: 16  WAFLPDLCLCRVFWWLGDRDRSRAALVCRKWNQMMYSAELWRYRTITFSGRPSRVHASEV 75
           W  LPD  L  +F  L   +  + + VC++W ++     LW+   +T       V    +
Sbjct: 97  WDSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLL 156

Query: 76  ESAV--------WYVKKFGRYLEHLEVKFMNPYNAVLTKKFQVTMRGLLSCLSKSNNRLK 127
              V        +  +    +     V+ M+  N+V+      T+ G+LS  SK    L+
Sbjct: 157 SQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVS---TLHGILSQCSK----LQ 209

Query: 128 SLSIQYLELDRLVWRNSIRSSFISSLSF------------FLKKMGKRLDYLNLKGARLT 175
           +LS++ L L   +     ++S +  L+              L     RLD LNL      
Sbjct: 210 NLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDF 269

Query: 176 VEQGCQILDSLSYMRNENVISELNIEDY 203
            E+  Q+    +       I++LN+  Y
Sbjct: 270 TEKHVQV----AVAHVSETITQLNLSGY 293


>gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo
           sapiens]
          Length = 410

 Score = 33.1 bits (74), Expect = 0.52
 Identities = 45/208 (21%), Positives = 80/208 (38%), Gaps = 31/208 (14%)

Query: 16  WAFLPDLCLCRVFWWLGDRDRSRAALVCRKWNQMMYSAELWRYRTITFSGRPSRVHASEV 75
           W  LPD  L  +F  L   +  + + VC++W ++     LW+   +T       V    +
Sbjct: 97  WDSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLL 156

Query: 76  ESAV--------WYVKKFGRYLEHLEVKFMNPYNAVLTKKFQVTMRGLLSCLSKSNNRLK 127
              V        +  +    +     V+ M+  N+V+      T+ G+LS  SK    L+
Sbjct: 157 SQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVS---TLHGILSQCSK----LQ 209

Query: 128 SLSIQYLELDRLVWRNSIRSSFISSLSF------------FLKKMGKRLDYLNLKGARLT 175
           +LS++ L L   +     ++S +  L+              L     RLD LNL      
Sbjct: 210 NLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDF 269

Query: 176 VEQGCQILDSLSYMRNENVISELNIEDY 203
            E+  Q+    +       I++LN+  Y
Sbjct: 270 TEKHVQV----AVAHVSETITQLNLSGY 293


>gi|157168349 F-box and leucine-rich repeat protein 19 [Homo
           sapiens]
          Length = 694

 Score = 32.3 bits (72), Expect = 0.88
 Identities = 15/38 (39%), Positives = 18/38 (47%)

Query: 19  LPDLCLCRVFWWLGDRDRSRAALVCRKWNQMMYSAELW 56
           LP     RVF  LG R+      VCR W++  Y   LW
Sbjct: 424 LPRAAWLRVFQHLGPRELCICMRVCRTWSRWCYDKRLW 461


>gi|22547146 F-box and leucine-rich repeat protein 8 [Homo sapiens]
          Length = 374

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 67/310 (21%), Positives = 114/310 (36%), Gaps = 50/310 (16%)

Query: 19  LPDLCLCRVFWWLGDRDRSRAALVCRKWNQMMYSAELWRYRTITFSGRPSRVHASEVESA 78
           LP+  L  +F  L  RDR+ AA VCR W      + +W    I+           E+E  
Sbjct: 8   LPEEVLALIFRHLSLRDRAAAARVCRAWAAAATCSAVWHDTKISCE--------CELEGM 59

Query: 79  V-WYVKKFGRYLEHLEVKF---MNPYNAVLTKKFQVT------MRGL-LSCLSKSNNRLK 127
           +  Y+     ++ +L ++F     P      +   V       +RGL L C  +    L 
Sbjct: 60  LPPYLSACLDHIHNLRLEFEPSRKPSRRAAIELLMVLAGRAPGLRGLRLEC--RGEKPLF 117

Query: 128 SLSIQYLELDRLVW--RNSIRSSFISSLSFFLKKMGKRLDYLNLKGARLTVEQGCQILDS 185
                 LE    V    + +R   +  LSF L       D L L+ AR      C  L S
Sbjct: 118 DAGRDVLEAVHAVCGAASQLRHLDLRRLSFTLD------DALVLQAAR-----SCPELHS 166

Query: 186 LSYMRNENVISELNIEDYFSHHLAVYNSPQFKKTMSTFHNLVSLNLNYNCISDELLENL- 244
           L ++ N  ++  +                   + +     L +L L+   +S  +LE L 
Sbjct: 167 L-FLDNSTLVGSV-------------GPGSVLELLEACPRLRALGLHLASLSHAILEALA 212

Query: 245 CENASTLRTINIKCHV-HDPHGQVIWGMSWAKLARQATNLKVNFFFERIMKYERLARILL 303
             + +    + ++C    D     +   +W  L R+   L V    E  +  E + R+L 
Sbjct: 213 APDRAPFALLALRCACPEDARASPLPNEAWVALRRRHPGLAVELELEPALPAESVTRVLQ 272

Query: 304 QEIPIRSISL 313
             +P+ ++ L
Sbjct: 273 PAVPVAALRL 282


>gi|67003566 F-box protein 48 [Homo sapiens]
          Length = 155

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 2/78 (2%)

Query: 1  MDEESELIQPQDQSCWAFLPDLCLCRVFWWLGDRDRSRAALVCRKWNQMMYSAE-LWRYR 59
          +D E E  + Q+ + +  LP     ++F  L  R   RA+L CR WN  + +++ LW+  
Sbjct: 21 VDAEKEKNESQN-NFFELLPAEITFKIFSQLDIRSLCRASLTCRSWNDTIRNSDSLWKPH 79

Query: 60 TITFSGRPSRVHASEVES 77
           +T      R    ++ES
Sbjct: 80 CMTVRAVCRREIDDDLES 97


>gi|33359221 dyslexia susceptibility 2-like [Homo sapiens]
          Length = 1049

 Score = 31.2 bits (69), Expect = 2.0
 Identities = 12/22 (54%), Positives = 12/22 (54%)

Query: 10  PQDQSCWAFLPDLCLCRVFWWL 31
           P  QSCWA       C VFWWL
Sbjct: 80  PSLQSCWAACCQDSACHVFWWL 101


>gi|110624785 NACHT, leucine rich repeat and PYD containing 13 [Homo
            sapiens]
          Length = 1043

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 35/152 (23%), Positives = 66/152 (43%), Gaps = 26/152 (17%)

Query: 117  SCLSKSNNRLKSLSIQYLELDRLVWRNSIRSSFISSLSFFLKKMGKRLDYLNLKGARLTV 176
            +C   S+  L++ S+ +L L +    NS+R   +  L   L +    L  LNL G   T 
Sbjct: 883  ACKHLSDALLQNRSLTHLNLSK----NSLRDEGVKFLCEALGRPDGNLQSLNLSGCSFTR 938

Query: 177  EQGCQILDSLSYMRNENV--ISELNIED--------YFSHHLAVYNSPQFK--------- 217
            E   ++ ++LS+  N  +  + E +++D            H A++     K         
Sbjct: 939  EGCGELANALSHNHNVKILDLGENDLQDDGVKLLCEALKPHRALHTLGLAKCNLTTACCQ 998

Query: 218  ---KTMSTFHNLVSLNLNYNCISDELLENLCE 246
                 +S+  +LV+LNL  N +  + ++ LC+
Sbjct: 999  HLFSVLSSSKSLVNLNLLGNELDTDGVKMLCK 1030


>gi|52426787 oligodendrocyte myelin glycoprotein [Homo sapiens]
          Length = 440

 Score = 30.0 bits (66), Expect = 4.4
 Identities = 26/97 (26%), Positives = 50/97 (51%), Gaps = 11/97 (11%)

Query: 225 NLVSLNLNYNCISDELLENLCENASTLRTINIKCH------VHDPHGQVIWGMSWAKLAR 278
           N++ LNL+YN  +D  L N     + LRT++I  +       H P    +W MS A    
Sbjct: 56  NIIHLNLSYNHFTD--LHNQLTQYTNLRTLDISNNRLESLPAHLPRS--LWNMSAANNNI 111

Query: 279 QATNLKVNFFFERIMKYERLARILLQEIPIRSISLRS 315
           +  + K +  ++  +KY  +++ +L+++ +   +LRS
Sbjct: 112 KLLD-KSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRS 147


>gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]
          Length = 423

 Score = 30.0 bits (66), Expect = 4.4
 Identities = 59/253 (23%), Positives = 96/253 (37%), Gaps = 45/253 (17%)

Query: 19  LPDLCLCRVFWWLGDRDRSRAALVCRKWNQMMYSAELWRYRTITFSGRPSRVHASEVESA 78
           LP   L R+F +L      R A + + WN +      W  + I        V    VE+ 
Sbjct: 15  LPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNW--QRIDLFNFQIDVEGRVVEN- 71

Query: 79  VWYVKKFGRYLEHLEVKFMNPYNAVLTKKFQVTMR-----GLLSCLSKSNNRLKSLS--- 130
               K+ G +L  L ++          K F    R      L  C   +++   SLS   
Sbjct: 72  --ISKRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFC 129

Query: 131 --IQYLELDRLVWRNSIRSSFISSLSFFLKKMGKRLDYLNLKGARLTVEQGCQILDSLSY 188
             +++L+L   V   SI +S +  +S    +  + L+YLNL       + G + L     
Sbjct: 130 SKLKHLDLTSCV---SITNSSLKGIS----EGCRNLEYLNLSWCDQITKDGIEAL----- 177

Query: 189 MRNENVISEL------NIEDYFSHHLAVYNSPQFKKTMSTFHNLVSLNL-NYNCISDELL 241
           +R    +  L       +ED    H+  Y            H LVSLNL + + I+DE +
Sbjct: 178 VRGCRGLKALLLRGCTQLEDEALKHIQNY-----------CHELVSLNLQSCSRITDEGV 226

Query: 242 ENLCENASTLRTI 254
             +C     L+ +
Sbjct: 227 VQICRGCHRLQAL 239


>gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [Homo
           sapiens]
          Length = 565

 Score = 29.3 bits (64), Expect = 7.5
 Identities = 11/40 (27%), Positives = 22/40 (55%)

Query: 19  LPDLCLCRVFWWLGDRDRSRAALVCRKWNQMMYSAELWRY 58
           LP   +  +F +L  ++  R + V  KW+Q+  +  LW++
Sbjct: 82  LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKH 121


>gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [Homo
           sapiens]
          Length = 691

 Score = 29.3 bits (64), Expect = 7.5
 Identities = 11/40 (27%), Positives = 22/40 (55%)

Query: 19  LPDLCLCRVFWWLGDRDRSRAALVCRKWNQMMYSAELWRY 58
           LP   +  +F +L  ++  R + V  KW+Q+  +  LW++
Sbjct: 208 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKH 247


>gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens]
          Length = 479

 Score = 29.3 bits (64), Expect = 7.5
 Identities = 12/49 (24%), Positives = 24/49 (48%), Gaps = 7/49 (14%)

Query: 27  VFWWLGDRDRSRAALVCRKWNQMMYSAELWRYRTITFSGRPSRVHASEV 75
           +FW+    ++   A VC+ W +++Y  + W       +G    +HA E+
Sbjct: 105 LFWYFSACEKCVLAQVCKAWRRVLYQPKFW-------AGLTPVLHAKEL 146


>gi|208609985 SH2 domain containing 3A [Homo sapiens]
          Length = 576

 Score = 28.9 bits (63), Expect = 9.8
 Identities = 17/51 (33%), Positives = 22/51 (43%), Gaps = 4/51 (7%)

Query: 316 CYFSDPDCSMRPTLIDLLPTFRHTLQKLTCEFNNNHESLDEELHLLIISCR 366
           C    P C + P    L P   HTL+ L  E    H      LHLL++ C+
Sbjct: 281 CPHDAPSCLLGPQNRPLEPQVLHTLRGLFLE----HHPGSTALHLLLVDCQ 327


>gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2 [Homo
           sapiens]
          Length = 533

 Score = 28.9 bits (63), Expect = 9.8
 Identities = 15/36 (41%), Positives = 20/36 (55%), Gaps = 6/36 (16%)

Query: 38  RAALVCRKWNQMMYSAELWRYRTITFS----GRPSR 69
           RAA VCR+W +      LW   T+T S    GRP++
Sbjct: 139 RAARVCRRWQEAASQPALW--HTVTLSSPLVGRPAK 172


>gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [Homo
           sapiens]
          Length = 539

 Score = 28.9 bits (63), Expect = 9.8
 Identities = 15/36 (41%), Positives = 20/36 (55%), Gaps = 6/36 (16%)

Query: 38  RAALVCRKWNQMMYSAELWRYRTITFS----GRPSR 69
           RAA VCR+W +      LW   T+T S    GRP++
Sbjct: 139 RAARVCRRWQEAASQPALW--HTVTLSSPLVGRPAK 172


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.136    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,634,336
Number of Sequences: 37866
Number of extensions: 635802
Number of successful extensions: 2040
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2017
Number of HSP's gapped (non-prelim): 32
length of query: 442
length of database: 18,247,518
effective HSP length: 105
effective length of query: 337
effective length of database: 14,271,588
effective search space: 4809525156
effective search space used: 4809525156
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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