BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|23238240 angiotensin II receptor, type 2 [Homo sapiens] (363 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|23238240 angiotensin II receptor, type 2 [Homo sapiens] 741 0.0 gi|14043066 angiotensin II receptor, type 1 [Homo sapiens] 220 2e-57 gi|14043064 angiotensin II receptor, type 1 [Homo sapiens] 220 2e-57 gi|14043062 angiotensin II receptor, type 1 [Homo sapiens] 220 2e-57 gi|6715583 angiotensin II receptor, type 1 [Homo sapiens] 220 2e-57 gi|4501997 angiotensin II receptor, type 1 [Homo sapiens] 220 2e-57 gi|4557359 bradykinin receptor B2 [Homo sapiens] 187 1e-47 gi|4502631 chemokine (C-C motif) receptor 1 [Homo sapiens] 183 2e-46 gi|183979982 chemokine (C-C motif) receptor 2 isoform B [Homo sa... 171 7e-43 gi|20544172 bradykinin receptor B1 [Homo sapiens] 170 2e-42 gi|183979980 chemokine (C-C motif) receptor 2 isoform A [Homo sa... 167 1e-41 gi|4885057 apelin receptor [Homo sapiens] 166 2e-41 gi|30581170 CC chemokine receptor 3 [Homo sapiens] 166 4e-41 gi|4502637 CC chemokine receptor 3 [Homo sapiens] 166 4e-41 gi|4885121 chemokine (C-C motif) receptor 8 [Homo sapiens] 165 7e-41 gi|4503171 chemokine (C-X3-C motif) receptor 1 [Homo sapiens] 164 1e-40 gi|13929467 chemokine binding protein 2 [Homo sapiens] 164 1e-40 gi|218563730 chemokine (C-X-C motif) receptor 3 isoform B [Homo ... 162 3e-40 gi|4504099 chemokine (C-X-C motif) receptor 3 isoform A [Homo sa... 162 3e-40 gi|4504683 interleukin 8 receptor beta [Homo sapiens] 162 6e-40 gi|31083344 chemokine orphan receptor 1 [Homo sapiens] 160 2e-39 gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo sa... 160 2e-39 gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo sa... 160 2e-39 gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo sap... 160 2e-39 gi|154091328 chemokine (C-C motif) receptor 5 [Homo sapiens] 158 6e-39 gi|4502639 chemokine (C-C motif) receptor 5 [Homo sapiens] 158 6e-39 gi|4557859 somatostatin receptor 2 [Homo sapiens] 155 4e-38 gi|4557861 somatostatin receptor 3 [Homo sapiens] 155 4e-38 gi|39725940 opioid receptor, kappa 1 [Homo sapiens] 155 4e-38 gi|14043044 chemokine (C-C motif) receptor 9 isoform B [Homo sap... 155 7e-38 >gi|23238240 angiotensin II receptor, type 2 [Homo sapiens] Length = 363 Score = 741 bits (1913), Expect = 0.0 Identities = 363/363 (100%), Positives = 363/363 (100%) Query: 1 MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFL 60 MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFL Sbjct: 1 MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFL 60 Query: 61 VNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVF 120 VNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVF Sbjct: 61 VNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVF 120 Query: 121 GSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFY 180 GSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFY Sbjct: 121 GSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFY 180 Query: 181 FRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLK 240 FRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLK Sbjct: 181 FRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLK 240 Query: 241 TNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLAL 300 TNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLAL Sbjct: 241 TNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLAL 300 Query: 301 PFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMET 360 PFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMET Sbjct: 301 PFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMET 360 Query: 361 FVS 363 FVS Sbjct: 361 FVS 363 >gi|14043066 angiotensin II receptor, type 1 [Homo sapiens] Length = 359 Score = 220 bits (560), Expect = 2e-57 Identities = 107/282 (37%), Positives = 164/282 (58%), Gaps = 2/282 (0%) Query: 47 IPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSY 106 IP LY IIFV+G N +VV + K V+S+++ NLA+ADL L TLPLWA Y + Sbjct: 31 IPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAM 90 Query: 107 RYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQ-RRNPWQASYIVP 165 Y W FG +CK+ + ++ N++AS+F +TC+S+DRY ++++P S+ RR A Sbjct: 91 EYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCI 150 Query: 166 LVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLI 225 ++W +A L+SLP R+V IE + C + + + G+ L KNILGF+ P + Sbjct: 151 IIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQN-STLPIGLGLTKNILGFLFPFL 209 Query: 226 FIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMG 285 I T Y I K L K KN+ D + K+ A+VL F W+P + TFLD L +G Sbjct: 210 IILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLG 269 Query: 286 VINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQ 327 +I C + ++D A+P I + + N+C+NP Y F+G +F++ Sbjct: 270 IIRDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKR 311 >gi|14043064 angiotensin II receptor, type 1 [Homo sapiens] Length = 359 Score = 220 bits (560), Expect = 2e-57 Identities = 107/282 (37%), Positives = 164/282 (58%), Gaps = 2/282 (0%) Query: 47 IPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSY 106 IP LY IIFV+G N +VV + K V+S+++ NLA+ADL L TLPLWA Y + Sbjct: 31 IPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAM 90 Query: 107 RYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQ-RRNPWQASYIVP 165 Y W FG +CK+ + ++ N++AS+F +TC+S+DRY ++++P S+ RR A Sbjct: 91 EYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCI 150 Query: 166 LVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLI 225 ++W +A L+SLP R+V IE + C + + + G+ L KNILGF+ P + Sbjct: 151 IIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQN-STLPIGLGLTKNILGFLFPFL 209 Query: 226 FIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMG 285 I T Y I K L K KN+ D + K+ A+VL F W+P + TFLD L +G Sbjct: 210 IILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLG 269 Query: 286 VINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQ 327 +I C + ++D A+P I + + N+C+NP Y F+G +F++ Sbjct: 270 IIRDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKR 311 >gi|14043062 angiotensin II receptor, type 1 [Homo sapiens] Length = 359 Score = 220 bits (560), Expect = 2e-57 Identities = 107/282 (37%), Positives = 164/282 (58%), Gaps = 2/282 (0%) Query: 47 IPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSY 106 IP LY IIFV+G N +VV + K V+S+++ NLA+ADL L TLPLWA Y + Sbjct: 31 IPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAM 90 Query: 107 RYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQ-RRNPWQASYIVP 165 Y W FG +CK+ + ++ N++AS+F +TC+S+DRY ++++P S+ RR A Sbjct: 91 EYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCI 150 Query: 166 LVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLI 225 ++W +A L+SLP R+V IE + C + + + G+ L KNILGF+ P + Sbjct: 151 IIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQN-STLPIGLGLTKNILGFLFPFL 209 Query: 226 FIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMG 285 I T Y I K L K KN+ D + K+ A+VL F W+P + TFLD L +G Sbjct: 210 IILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLG 269 Query: 286 VINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQ 327 +I C + ++D A+P I + + N+C+NP Y F+G +F++ Sbjct: 270 IIRDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKR 311 >gi|6715583 angiotensin II receptor, type 1 [Homo sapiens] Length = 359 Score = 220 bits (560), Expect = 2e-57 Identities = 107/282 (37%), Positives = 164/282 (58%), Gaps = 2/282 (0%) Query: 47 IPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSY 106 IP LY IIFV+G N +VV + K V+S+++ NLA+ADL L TLPLWA Y + Sbjct: 31 IPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAM 90 Query: 107 RYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQ-RRNPWQASYIVP 165 Y W FG +CK+ + ++ N++AS+F +TC+S+DRY ++++P S+ RR A Sbjct: 91 EYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCI 150 Query: 166 LVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLI 225 ++W +A L+SLP R+V IE + C + + + G+ L KNILGF+ P + Sbjct: 151 IIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQN-STLPIGLGLTKNILGFLFPFL 209 Query: 226 FIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMG 285 I T Y I K L K KN+ D + K+ A+VL F W+P + TFLD L +G Sbjct: 210 IILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLG 269 Query: 286 VINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQ 327 +I C + ++D A+P I + + N+C+NP Y F+G +F++ Sbjct: 270 IIRDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKR 311 >gi|4501997 angiotensin II receptor, type 1 [Homo sapiens] Length = 359 Score = 220 bits (560), Expect = 2e-57 Identities = 107/282 (37%), Positives = 164/282 (58%), Gaps = 2/282 (0%) Query: 47 IPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSY 106 IP LY IIFV+G N +VV + K V+S+++ NLA+ADL L TLPLWA Y + Sbjct: 31 IPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAM 90 Query: 107 RYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQ-RRNPWQASYIVP 165 Y W FG +CK+ + ++ N++AS+F +TC+S+DRY ++++P S+ RR A Sbjct: 91 EYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCI 150 Query: 166 LVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLI 225 ++W +A L+SLP R+V IE + C + + + G+ L KNILGF+ P + Sbjct: 151 IIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQN-STLPIGLGLTKNILGFLFPFL 209 Query: 226 FIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMG 285 I T Y I K L K KN+ D + K+ A+VL F W+P + TFLD L +G Sbjct: 210 IILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLG 269 Query: 286 VINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQ 327 +I C + ++D A+P I + + N+C+NP Y F+G +F++ Sbjct: 270 IIRDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKR 311 >gi|4557359 bradykinin receptor B2 [Homo sapiens] Length = 391 Score = 187 bits (476), Expect = 1e-47 Identities = 99/292 (33%), Positives = 165/292 (56%), Gaps = 9/292 (3%) Query: 48 PILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYR 107 P +++FV+ L NI V+++FC K V+ IY+ NLA ADL+L LP WA S Sbjct: 61 PPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISNN 120 Query: 108 YDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPF-LSQRRNPWQASYIVPL 166 +DWLFG +C+V + +++N+++SI F+ +S+DRY +++ + + R A + Sbjct: 121 FDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLV 180 Query: 167 VWCMACLSSLPTFYFRDVRTIEYLG--VNACIMAFPPEKYAQWSAGIALMKNILGFIIPL 224 +W L S P FR ++ G V AC++++P W ++ N++GF++PL Sbjct: 181 IWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPS---LIWEVFTNMLLNVVGFLLPL 237 Query: 225 IFIATCYFGIRKHLLKTNSYGKNR--ITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALA 282 I C I + +L+ N K + T + + V+L FIICWLPF + TFLD L Sbjct: 238 SVITFCTMQIMQ-VLRNNEMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLH 296 Query: 283 WMGVINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFR 334 +G+++SC+ +ID+ A + ++NSC+NP +Y VG RF++K V++ Sbjct: 297 RLGILSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVYQ 348 >gi|4502631 chemokine (C-C motif) receptor 1 [Homo sapiens] Length = 355 Score = 183 bits (465), Expect = 2e-46 Identities = 98/300 (32%), Positives = 164/300 (54%), Gaps = 11/300 (3%) Query: 37 QKPSDKHLDA--IPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLL 94 QK +++ A +P LY ++FVIG + NI+VV + K K ++SIY+ NLA++DLL L Sbjct: 25 QKVNERAFGAQLLPPLYSLVFVIGLVGNILVVLVLVQYKRLKNMTSIYLLNLAISDLLFL 84 Query: 95 ATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQR 154 TLP W Y + DW+FG MCK+ F +++ IFFI +++DRY ++++ + R Sbjct: 85 FTLPFWID-YKLKDDWVFGDAMCKILSGFYYTGLYSEIFFIILLTIDRYLAIVHAVFALR 143 Query: 155 RNPWQASYIVP-LVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIAL 213 I ++W +A L+S+P YF +T + C + FP E +W AL Sbjct: 144 ARTVTFGVITSIIIWALAILASMPGLYFS--KTQWEFTHHTCSLHFPHESLREWKLFQAL 201 Query: 214 MKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFH 273 N+ G ++PL+ + CY GI K LL+ + K++ R + +++ F + W P++ Sbjct: 202 KLNLFGLVLPLLVMIICYTGIIKILLRRPNEKKSKAVR-----LIFVIMIIFFLFWTPYN 256 Query: 274 VLTFLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVF 333 + + + CE +DLA+ ++ +T+ CVNP +Y FVG RF++ LR +F Sbjct: 257 LTILISVFQDFLFTHECEQSRHLDLAVQVTEVIAYTHCCVNPVIYAFVGERFRKYLRQLF 316 >gi|183979982 chemokine (C-C motif) receptor 2 isoform B [Homo sapiens] Length = 360 Score = 171 bits (434), Expect = 7e-43 Identities = 91/293 (31%), Positives = 160/293 (54%), Gaps = 13/293 (4%) Query: 47 IPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSY 106 +P LY ++F+ GF+ N++VV + K K ++ IY+ NLA++DLL L TLPLWA +S Sbjct: 45 LPPLYSLVFIFGFVGNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWA--HSA 102 Query: 107 RYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPL 166 +W+FG MCK+F + F IFFI +++DRY ++++ + + + + Sbjct: 103 ANEWVFGNAMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSV 162 Query: 167 V-WCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLI 225 + W +A +S+P F + + V C FP W+ +M+NILG ++PL+ Sbjct: 163 ITWLVAVFASVPGIIFTKCQKED--SVYVCGPYFP----RGWNNFHTIMRNILGLVLPLL 216 Query: 226 FIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMG 285 + CY GI K LL+ +N R + +++ +++ + + W P++++ L+ Sbjct: 217 IMVICYSGILKTLLRC----RNEKKRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFF 272 Query: 286 VINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPIT 338 +++CE + +D A LG T+ C+NP +Y FVG +F++ L FR IT Sbjct: 273 GLSNCESTSQLDQATQVTETLGMTHCCINPIIYAFVGEKFRRYLSVFFRKHIT 325 >gi|20544172 bradykinin receptor B1 [Homo sapiens] Length = 353 Score = 170 bits (431), Expect = 2e-42 Identities = 94/292 (32%), Positives = 149/292 (51%), Gaps = 7/292 (2%) Query: 47 IPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSY 106 +P I G L N+ V+ +F + V+ IY+ NLA +DL+ + LP WA Sbjct: 40 LPTFIISICFFGLLGNLFVLLVFLLPRRQLNVAEIYLANLAASDLVFVLGLPFWAENIWN 99 Query: 107 RYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQR-RNPWQASYIVP 165 +++W FG ++C+V + N+F SIF + +S DRY+ +++P S+R + QA Sbjct: 100 QFNWPFGALLCRVINGVIKANLFISIFLVVAISQDRYRVLVHPMASRRQQRRRQARVTCV 159 Query: 166 LVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLI 225 L+W + L S+PTF R ++ + L + ACI+ P E W + NILGF++PL Sbjct: 160 LIWVVGGLLSIPTFLLRSIQAVPDLNITACILLLPHE---AWHFARIVELNILGFLLPLA 216 Query: 226 FIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAV---VLAFIICWLPFHVLTFLDALA 282 I + I L + R + K A + V+AF++CW P+H FL+ L Sbjct: 217 AIVFFNYHILASLRTREEVSRTRCGGRKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLF 276 Query: 283 WMGVINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFR 334 + + C IDL L A FTNS +NP +Y FVG F+ K+ +++ Sbjct: 277 QVQAVRGCFWEDFIDLGLQLANFFAFTNSSLNPVIYVFVGRLFRTKVWELYK 328 >gi|183979980 chemokine (C-C motif) receptor 2 isoform A [Homo sapiens] Length = 374 Score = 167 bits (423), Expect = 1e-41 Identities = 89/292 (30%), Positives = 159/292 (54%), Gaps = 17/292 (5%) Query: 47 IPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSY 106 +P LY ++F+ GF+ N++VV + K K ++ IY+ NLA++DLL L TLPLWA +S Sbjct: 45 LPPLYSLVFIFGFVGNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWA--HSA 102 Query: 107 RYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPL 166 +W+FG MCK+F + F IFFI +++DRY ++++ + + + + Sbjct: 103 ANEWVFGNAMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSV 162 Query: 167 V-WCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLI 225 + W +A +S+P F + + V C FP W+ +M+NILG ++PL+ Sbjct: 163 ITWLVAVFASVPGIIFTKCQKED--SVYVCGPYFP----RGWNNFHTIMRNILGLVLPLL 216 Query: 226 FIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMG 285 + CY GI K LL+ +N R + +++ +++ + + W P++++ L+ Sbjct: 217 IMVICYSGILKTLLRC----RNEKKRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFF 272 Query: 286 VINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPI 337 +++CE + +D A LG T+ C+NP +Y FVG +F RS+F + + Sbjct: 273 GLSNCESTSQLDQATQVTETLGMTHCCINPIIYAFVGEKF----RSLFHIAL 320 >gi|4885057 apelin receptor [Homo sapiens] Length = 380 Score = 166 bits (421), Expect = 2e-41 Identities = 99/319 (31%), Positives = 165/319 (51%), Gaps = 15/319 (4%) Query: 47 IPILYYIIFVIGFLVN-IVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYS 105 IP +Y ++F++G N +V+ T+F + ++ + I+I +LAVADL + TLPLWATY Sbjct: 31 IPAIYMLVFLLGTTGNGLVLWTVFRSSREKRRSADIFIASLAVADLTFVVTLPLWATYTY 90 Query: 106 YRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQR-RNPWQASYIV 164 YDW FG CK+ + +NM+AS+F +T +S DRY +++ P + R R + Sbjct: 91 RDYDWPFGTFFCKLSSYLIFVNMYASVFCLTGLSFDRYLAIVRPVANARLRLRVSGAVAT 150 Query: 165 PLVWCMACLSSLPTFYFRDVRTIEYLGVNACIM-----AFPPEKYAQWSAGIALMKNILG 219 ++W +A L ++P R +E C M A ++A W G+ + +G Sbjct: 151 AVLWVLAALLAMPVMVLRTTGDLENTTKVQCYMDYSMVATVSSEWA-WEVGLGVSSTTVG 209 Query: 220 FIIPLIFIATCYFGIRKHLLKTNSYGKNRI----TRDQVLKMAAAVVLAFIICWLPFHVL 275 F++P + TCYF I + + + K RI R ++L + +V+ F +CW+P+H++ Sbjct: 210 FVVPFTIMLTCYFFIAQTI--AGHFRKERIEGLRKRRRLLSIIVVLVVTFALCWMPYHLV 267 Query: 276 TFLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRV 335 L L + + C+ + P+ + + NSC+NPFLY F RF+Q S+ Sbjct: 268 KTLYMLGSL-LHWPCDFDLFLMNIFPYCTCISYVNSCLNPFLYAFFDPRFRQACTSMLCC 326 Query: 336 PITWLQGKRESMSCRKSSS 354 + G S S KS+S Sbjct: 327 GQSRCAGTSHSSSGEKSAS 345 >gi|30581170 CC chemokine receptor 3 [Homo sapiens] Length = 355 Score = 166 bits (419), Expect = 4e-41 Identities = 90/288 (31%), Positives = 153/288 (53%), Gaps = 9/288 (3%) Query: 47 IPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSY 106 +P LY ++F +G L N+VVV + + + +++IY+ NLA++DLL L TLP W +Y Sbjct: 37 VPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFW-IHYVR 95 Query: 107 RYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPL 166 ++W+FG MCK+ F +++ IFFI +++DRY ++++ + R I + Sbjct: 96 GHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSI 155 Query: 167 V-WCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLI 225 V W +A L++LP F F + T E C +P + W L I ++PL+ Sbjct: 156 VTWGLAVLAALPEFIFYE--TEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLL 213 Query: 226 FIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMG 285 +A CY GI K LL+ S K + +++ ++ F I W P++V L + + Sbjct: 214 VMAICYTGIIKTLLRCPSKKKYK-----AIRLIFVIMAVFFIFWTPYNVAILLSSYQSIL 268 Query: 286 VINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVF 333 N CE +DL + ++ +++ C+NP +Y FVG RF++ LR F Sbjct: 269 FGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFF 316 >gi|4502637 CC chemokine receptor 3 [Homo sapiens] Length = 355 Score = 166 bits (419), Expect = 4e-41 Identities = 90/288 (31%), Positives = 153/288 (53%), Gaps = 9/288 (3%) Query: 47 IPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSY 106 +P LY ++F +G L N+VVV + + + +++IY+ NLA++DLL L TLP W +Y Sbjct: 37 VPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFW-IHYVR 95 Query: 107 RYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPL 166 ++W+FG MCK+ F +++ IFFI +++DRY ++++ + R I + Sbjct: 96 GHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSI 155 Query: 167 V-WCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLI 225 V W +A L++LP F F + T E C +P + W L I ++PL+ Sbjct: 156 VTWGLAVLAALPEFIFYE--TEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLL 213 Query: 226 FIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMG 285 +A CY GI K LL+ S K + +++ ++ F I W P++V L + + Sbjct: 214 VMAICYTGIIKTLLRCPSKKKYK-----AIRLIFVIMAVFFIFWTPYNVAILLSSYQSIL 268 Query: 286 VINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVF 333 N CE +DL + ++ +++ C+NP +Y FVG RF++ LR F Sbjct: 269 FGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFF 316 >gi|4885121 chemokine (C-C motif) receptor 8 [Homo sapiens] Length = 355 Score = 165 bits (417), Expect = 7e-41 Identities = 95/316 (30%), Positives = 167/316 (52%), Gaps = 15/316 (4%) Query: 47 IPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSY 106 + + Y ++FV L N +V+ + K + ++ +Y+ NLA++DLL + + P + TYY Sbjct: 38 LAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFP-FQTYYLL 96 Query: 107 RYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQR-RNPWQASYIVP 165 W+FG VMCKV F + ++S+FFIT MSVDRY +V++ + + R + + Sbjct: 97 D-QWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCL 155 Query: 166 LVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLI 225 VW A ++++P F V + + GV C +F ++ +W NILG +IP Sbjct: 156 AVWLTAIMATIPLLVFYQVASED--GVLQCY-SFYNQQTLKWKIFTNFKMNILGLLIPFT 212 Query: 226 FIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMG 285 CY I L + ++ K + +++ VV+A ++ W+PF+V+ FL +L M Sbjct: 213 IFMFCYIKILHQLKRCQNHNKTK-----AIRLVLIVVIASLLFWVPFNVVLFLTSLHSMH 267 Query: 286 VINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVP----ITWLQ 341 +++ C + + A ++ FT+ CVNP +Y FVG +F++ L +F+ +L Sbjct: 268 ILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLG 327 Query: 342 GKRESMSCRKSSSLRE 357 + SC KSSS ++ Sbjct: 328 RQMPRESCEKSSSCQQ 343 >gi|4503171 chemokine (C-X3-C motif) receptor 1 [Homo sapiens] Length = 355 Score = 164 bits (415), Expect = 1e-40 Identities = 99/311 (31%), Positives = 156/311 (50%), Gaps = 14/311 (4%) Query: 47 IPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSY 106 + I Y +IF IG + N++VV K PK V+ IY+ NLA++DLL +ATLP W T+Y Sbjct: 34 LSIFYSVIFAIGLVGNLLVVFALTNSKKPKSVTDIYLLNLALSDLLFVATLPFW-THYLI 92 Query: 107 RYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPL 166 L MCK +F + F SIFFIT +S+DRY +++ S Q + L Sbjct: 93 NEKGLHN-AMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAANSMNNRTVQHGVTISL 151 Query: 167 -VWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLI 225 VW A L + P F F + N C+ +P W + N LGF++PL+ Sbjct: 152 GVWAAAILVAAPQFMFTKQKE------NECLGDYPEVLQEIWPVLRNVETNFLGFLLPLL 205 Query: 226 FIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMG 285 ++ CYF I + L ++ K + +K+ VV+ F + W P++V+ FL+ L Sbjct: 206 IMSYCYFRIIQTLFSCKNHKKAK-----AIKLILLVVIVFFLFWTPYNVMIFLETLKLYD 260 Query: 286 VINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRE 345 SC++ + LAL + F++ C+NP +Y F G +F++ L ++ + L G+ Sbjct: 261 FFPSCDMRKDLRLALSVTETVAFSHCCLNPLIYAFAGEKFRRYLYHLYGKCLAVLCGRSV 320 Query: 346 SMSCRKSSSLR 356 + S S R Sbjct: 321 HVDFSSSESQR 331 >gi|13929467 chemokine binding protein 2 [Homo sapiens] Length = 384 Score = 164 bits (414), Expect = 1e-40 Identities = 99/319 (31%), Positives = 167/319 (52%), Gaps = 16/319 (5%) Query: 47 IPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSY 106 +P+ Y +IFV+G N++++ + +++ IY+ NLA+++LL L TLP W S Sbjct: 49 LPVFYSLIFVLGLSGNLLLLMVLLRYVPRRRMVEIYLLNLAISNLLFLVTLPFWGI--SV 106 Query: 107 RYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQR-RNPWQASYIVP 165 + W+FG +CK+ + T+N ++ IFFI+CMS+D+Y +++ R R ++ + Sbjct: 107 AWHWVFGSFLCKMVSTLYTINFYSGIFFISCMSLDKYLEIVHAQPYHRLRTRAKSLLLAT 166 Query: 166 LVWCMACLSSLPTFYFRDVRTIEY-LGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPL 224 +VW ++ S+P F V+T E GV C F W + +N+LGF++PL Sbjct: 167 IVWAVSLAVSIPDMVF--VQTHENPKGVWNCHADFGGHGTI-WKLFLRFQQNLLGFLLPL 223 Query: 225 IFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWM 284 + + Y I L++ G+ R LK+AAA+V+AF + W P+++ FL L + Sbjct: 224 LAMIFFYSRIGCVLVRLRPAGQGR-----ALKIAAALVVAFFVLWFPYNLTLFLHTLLDL 278 Query: 285 GVINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWL---- 340 V +CEV +D AL + F + C +P LY F +RF+Q L++ + W Sbjct: 279 QVFGNCEVSQHLDYALQVTESIAFLHCCFSPILYAFSSHRFRQYLKAFLAAVLGWHLAPG 338 Query: 341 QGKRESMSCRKSSSLREME 359 + SC +SS L E Sbjct: 339 TAQASLSSCSESSILTAQE 357 >gi|218563730 chemokine (C-X-C motif) receptor 3 isoform B [Homo sapiens] Length = 415 Score = 162 bits (411), Expect = 3e-40 Identities = 103/341 (30%), Positives = 175/341 (51%), Gaps = 21/341 (6%) Query: 27 GNNESTLNCSQKPSDKHLDA------IPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSS 80 G NES C+ P + +P LY ++F++G L N V + ++ + Sbjct: 77 GENESDSCCTSPPCPQDFSLNFDRAFLPALYSLLFLLGLLGNGAVAAVLLSRRTALSSTD 136 Query: 81 IYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSV 140 ++ +LAVAD LL+ TLPLWA + + W+FG +CKV G+ +N +A + C+S Sbjct: 137 TFLLHLAVADTLLVLTLPLWAVDAAVQ--WVFGSGLCKVAGALFNINFYAGALLLACISF 194 Query: 141 DRYQSVIYPFLSQRRNPWQASYIVPL-VWCMACLSSLPTFYFRDVRTIEYLGVNACIMAF 199 DRY ++++ RR P + L VW + L +LP F F E L C F Sbjct: 195 DRYLNIVHATQLYRRGPPARVTLTCLAVWGLCLLFALPDFIFLSAHHDERLNATHCQYNF 254 Query: 200 PPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAA 259 P + +++ + GF++PL+ +A CY I LL S G+ R+ + +++ Sbjct: 255 P----QVGRTALRVLQLVAGFLLPLLVMAYCYAHILAVLLV--SRGQRRL---RAMRLVV 305 Query: 260 AVVLAFIICWLPFHVLTFLDALAWMGVI-NSCEVIAVIDLALPFAILLGFTNSCVNPFLY 318 VV+AF +CW P+H++ +D L +G + +C + +D+A LG+ + C+NP LY Sbjct: 306 VVVVAFALCWTPYHLVVLVDILMDLGALARNCGRESRVDVAKSVTSGLGYMHCCLNPLLY 365 Query: 319 CFVGNRFQQKL-RSVFRVPITWLQG-KRESMSCRKSSSLRE 357 FVG +F++++ + R+ +G +R+ S R+ SS E Sbjct: 366 AFVGVKFRERMWMLLLRLGCPNQRGLQRQPSSSRRDSSWSE 406 >gi|4504099 chemokine (C-X-C motif) receptor 3 isoform A [Homo sapiens] Length = 368 Score = 162 bits (411), Expect = 3e-40 Identities = 103/341 (30%), Positives = 175/341 (51%), Gaps = 21/341 (6%) Query: 27 GNNESTLNCSQKPSDKHLDA------IPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSS 80 G NES C+ P + +P LY ++F++G L N V + ++ + Sbjct: 30 GENESDSCCTSPPCPQDFSLNFDRAFLPALYSLLFLLGLLGNGAVAAVLLSRRTALSSTD 89 Query: 81 IYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSV 140 ++ +LAVAD LL+ TLPLWA + + W+FG +CKV G+ +N +A + C+S Sbjct: 90 TFLLHLAVADTLLVLTLPLWAVDAAVQ--WVFGSGLCKVAGALFNINFYAGALLLACISF 147 Query: 141 DRYQSVIYPFLSQRRNPWQASYIVPL-VWCMACLSSLPTFYFRDVRTIEYLGVNACIMAF 199 DRY ++++ RR P + L VW + L +LP F F E L C F Sbjct: 148 DRYLNIVHATQLYRRGPPARVTLTCLAVWGLCLLFALPDFIFLSAHHDERLNATHCQYNF 207 Query: 200 PPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAA 259 P + +++ + GF++PL+ +A CY I LL S G+ R+ + +++ Sbjct: 208 P----QVGRTALRVLQLVAGFLLPLLVMAYCYAHILAVLLV--SRGQRRL---RAMRLVV 258 Query: 260 AVVLAFIICWLPFHVLTFLDALAWMGVI-NSCEVIAVIDLALPFAILLGFTNSCVNPFLY 318 VV+AF +CW P+H++ +D L +G + +C + +D+A LG+ + C+NP LY Sbjct: 259 VVVVAFALCWTPYHLVVLVDILMDLGALARNCGRESRVDVAKSVTSGLGYMHCCLNPLLY 318 Query: 319 CFVGNRFQQKL-RSVFRVPITWLQG-KRESMSCRKSSSLRE 357 FVG +F++++ + R+ +G +R+ S R+ SS E Sbjct: 319 AFVGVKFRERMWMLLLRLGCPNQRGLQRQPSSSRRDSSWSE 359 >gi|4504683 interleukin 8 receptor beta [Homo sapiens] Length = 360 Score = 162 bits (409), Expect = 6e-40 Identities = 88/290 (30%), Positives = 153/290 (52%), Gaps = 10/290 (3%) Query: 47 IPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSY 106 + I+Y ++F++ L N +V+ + + + V+ +Y+ NLA+ADLL TLP+WA S Sbjct: 51 VVIIYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAA--SK 108 Query: 107 RYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPL 166 W+FG +CKV +N ++ I + C+SVDRY ++++ + + + +I Sbjct: 109 VNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYLVKFICLS 168 Query: 167 VWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIF 226 +W ++ L +LP FR RT+ V+ A W + ++ GFI+PL+ Sbjct: 169 IWGLSLLLALPVLLFR--RTVYSSNVSPACYEDMGNNTANWRMLLRILPQSFGFIVPLLI 226 Query: 227 IATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGV 286 + CY + L K + K+R +++ AVVL F++CWLP++++ D L V Sbjct: 227 MLFCYGFTLRTLFKAHMGQKHR-----AMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQV 281 Query: 287 I-NSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRV 335 I +CE ID AL +LG +SC+NP +Y F+G +F+ L + + Sbjct: 282 IQETCERRNHIDRALDATEILGILHSCLNPLIYAFIGQKFRHGLLKILAI 331 >gi|31083344 chemokine orphan receptor 1 [Homo sapiens] Length = 362 Score = 160 bits (405), Expect = 2e-39 Identities = 96/305 (31%), Positives = 145/305 (47%), Gaps = 8/305 (2%) Query: 32 TLNCSQKPSDKHL-DAIPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVAD 90 T+ C P+ L + +Y IFVIG + N VVV + K + YI NLA+AD Sbjct: 31 TVMCPNMPNKSVLLYTLSFIYIFIFVIGMIANSVVVWVNIQAKTTGYDTHCYILNLAIAD 90 Query: 91 LLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIY-P 149 L ++ T+P+W W G + CKV ++N+F SIFF+TCMSVDRY S+ Y Sbjct: 91 LWVVLTIPVWVVSLVQHNQWPMGELTCKVTHLIFSINLFGSIFFLTCMSVDRYLSITYFT 150 Query: 150 FLSQRRNPWQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSA 209 R + LVW +A SLP Y+ T C +P +W Sbjct: 151 NTPSSRKKMVRRVVCILVWLLAFCVSLPDTYYLKTVTSASNNETYCRSFYPEHSIKEWLI 210 Query: 210 GIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICW 269 G+ L+ +LGF +P IA YF + + + ++ K+ K+ + V+ F++CW Sbjct: 211 GMELVSVVLGFAVPFSIIAVFYFLLARAISASSDQEKH-----SSRKIIFSYVVVFLVCW 265 Query: 270 LPFHVLTFLDALAWMGVIN-SCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQK 328 LP+HV LD + + I +C + + AL L + CVNP LY F+ ++ + Sbjct: 266 LPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVTQCLSLVHCCVNPVLYSFINRNYRYE 325 Query: 329 LRSVF 333 L F Sbjct: 326 LMKAF 330 >gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo sapiens] Length = 344 Score = 160 bits (404), Expect = 2e-39 Identities = 82/282 (29%), Positives = 146/282 (51%), Gaps = 2/282 (0%) Query: 50 LYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYD 109 ++ ++FV+G + N V + +F C + ++ Y+ NLA++DLL + TLP Y++ R + Sbjct: 23 MFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVFTLPFRIFYFTTR-N 81 Query: 110 WLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQR-RNPWQASYIVPLVW 168 W FG ++CK+ NM+ SI F+TC+SVDR+ +++YPF S+ R A + VW Sbjct: 82 WPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKTLRTKRNAKIVCTGVW 141 Query: 169 CMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIA 228 S P + + + AC FP + + + I + I+GF IPLI Sbjct: 142 LTVIGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRIVIFIEIVGFFIPLILNV 201 Query: 229 TCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVIN 288 TC + K L K + +++I + +VLKM ++ F C++P+++ L +L Sbjct: 202 TCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVPYNINLILYSLVRTQTFV 261 Query: 289 SCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLR 330 +C V+A + P + + +N C +P +Y F + Q ++ Sbjct: 262 NCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQNSIK 303 >gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo sapiens] Length = 344 Score = 160 bits (404), Expect = 2e-39 Identities = 82/282 (29%), Positives = 146/282 (51%), Gaps = 2/282 (0%) Query: 50 LYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYD 109 ++ ++FV+G + N V + +F C + ++ Y+ NLA++DLL + TLP Y++ R + Sbjct: 23 MFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVFTLPFRIFYFTTR-N 81 Query: 110 WLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQR-RNPWQASYIVPLVW 168 W FG ++CK+ NM+ SI F+TC+SVDR+ +++YPF S+ R A + VW Sbjct: 82 WPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKTLRTKRNAKIVCTGVW 141 Query: 169 CMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIA 228 S P + + + AC FP + + + I + I+GF IPLI Sbjct: 142 LTVIGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRIVIFIEIVGFFIPLILNV 201 Query: 229 TCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVIN 288 TC + K L K + +++I + +VLKM ++ F C++P+++ L +L Sbjct: 202 TCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVPYNINLILYSLVRTQTFV 261 Query: 289 SCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLR 330 +C V+A + P + + +N C +P +Y F + Q ++ Sbjct: 262 NCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQNSIK 303 >gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo sapiens] Length = 344 Score = 160 bits (404), Expect = 2e-39 Identities = 82/282 (29%), Positives = 146/282 (51%), Gaps = 2/282 (0%) Query: 50 LYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYD 109 ++ ++FV+G + N V + +F C + ++ Y+ NLA++DLL + TLP Y++ R + Sbjct: 23 MFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVFTLPFRIFYFTTR-N 81 Query: 110 WLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQR-RNPWQASYIVPLVW 168 W FG ++CK+ NM+ SI F+TC+SVDR+ +++YPF S+ R A + VW Sbjct: 82 WPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKTLRTKRNAKIVCTGVW 141 Query: 169 CMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIA 228 S P + + + AC FP + + + I + I+GF IPLI Sbjct: 142 LTVIGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRIVIFIEIVGFFIPLILNV 201 Query: 229 TCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVIN 288 TC + K L K + +++I + +VLKM ++ F C++P+++ L +L Sbjct: 202 TCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVPYNINLILYSLVRTQTFV 261 Query: 289 SCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLR 330 +C V+A + P + + +N C +P +Y F + Q ++ Sbjct: 262 NCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQNSIK 303 >gi|154091328 chemokine (C-C motif) receptor 5 [Homo sapiens] Length = 352 Score = 158 bits (400), Expect = 6e-39 Identities = 90/309 (29%), Positives = 160/309 (51%), Gaps = 11/309 (3%) Query: 29 NESTLNCSQKPSDKHLDA--IPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNL 86 N T QK + K + A +P LY ++F+ GF+ N++V+ + K K ++ IY+ NL Sbjct: 13 NYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKRLKSMTDIYLLNL 72 Query: 87 AVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSV 146 A++DL L T+P WA Y + ++D FG MC++ + F+ IFFI +++DRY +V Sbjct: 73 AISDLFFLLTVPFWAHYAAAQWD--FGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAV 130 Query: 147 IYPFLSQRRNPWQASYIVPLV-WCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYA 205 ++ + + + ++ W +A +SLP F R+ + C FP +Y Sbjct: 131 VHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIF--TRSQKEGLHYTCSSHFPYSQYQ 188 Query: 206 QWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAF 265 W L ILG ++PL+ + CY GI K LL+ +N R + +++ +++ + Sbjct: 189 FWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRC----RNEKKRHRAVRLIFTIMIVY 244 Query: 266 IICWLPFHVLTFLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRF 325 + W P++++ L+ +N+C +D A+ LG T+ C+NP +Y FVG +F Sbjct: 245 FLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKF 304 Query: 326 QQKLRSVFR 334 + L F+ Sbjct: 305 RNYLLVFFQ 313 >gi|4502639 chemokine (C-C motif) receptor 5 [Homo sapiens] Length = 352 Score = 158 bits (400), Expect = 6e-39 Identities = 90/309 (29%), Positives = 160/309 (51%), Gaps = 11/309 (3%) Query: 29 NESTLNCSQKPSDKHLDA--IPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNL 86 N T QK + K + A +P LY ++F+ GF+ N++V+ + K K ++ IY+ NL Sbjct: 13 NYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKRLKSMTDIYLLNL 72 Query: 87 AVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSV 146 A++DL L T+P WA Y + ++D FG MC++ + F+ IFFI +++DRY +V Sbjct: 73 AISDLFFLLTVPFWAHYAAAQWD--FGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAV 130 Query: 147 IYPFLSQRRNPWQASYIVPLV-WCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYA 205 ++ + + + ++ W +A +SLP F R+ + C FP +Y Sbjct: 131 VHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIF--TRSQKEGLHYTCSSHFPYSQYQ 188 Query: 206 QWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAF 265 W L ILG ++PL+ + CY GI K LL+ +N R + +++ +++ + Sbjct: 189 FWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRC----RNEKKRHRAVRLIFTIMIVY 244 Query: 266 IICWLPFHVLTFLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRF 325 + W P++++ L+ +N+C +D A+ LG T+ C+NP +Y FVG +F Sbjct: 245 FLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKF 304 Query: 326 QQKLRSVFR 334 + L F+ Sbjct: 305 RNYLLVFFQ 313 >gi|4557859 somatostatin receptor 2 [Homo sapiens] Length = 369 Score = 155 bits (393), Expect = 4e-38 Identities = 100/319 (31%), Positives = 166/319 (52%), Gaps = 20/319 (6%) Query: 47 IPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSY 106 + +Y+++ +IG N +V+ + K +++IYI NLA+AD L + LP A + Sbjct: 46 LTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVAL 105 Query: 107 RYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQR-RNPWQASYIVP 165 + W FG +C+V + +N F SIF +T MS+DRY +V++P S + R P A I Sbjct: 106 VH-WPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITM 164 Query: 166 LVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLI 225 VW ++ L LP + +R+ ++ G ++C + +P E A W G + ILGF++PL Sbjct: 165 AVWGVSLLVILPIMIYAGLRSNQW-GRSSCTINWPGESGA-WYTGFIIYTFILGFLVPLT 222 Query: 226 FIATCYFGIRKHLLKTNSYG------KNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLD 279 I CY I ++K S G K + + +V +M + VV FI CWLPF++ F Sbjct: 223 IICLCYLFI---IIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYI--FNV 277 Query: 280 ALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVF-RVPIT 338 + M + + + + D F ++L + NSC NP LY F+ + F++ ++V V ++ Sbjct: 278 SSVSMAISPTPALKGMFD----FVVVLTYANSCANPILYAFLSDNFKKSFQNVLCLVKVS 333 Query: 339 WLQGKRESMSCRKSSSLRE 357 S S + S L E Sbjct: 334 GTDDGERSDSKQDKSRLNE 352 >gi|4557861 somatostatin receptor 3 [Homo sapiens] Length = 418 Score = 155 bits (393), Expect = 4e-38 Identities = 102/300 (34%), Positives = 154/300 (51%), Gaps = 25/300 (8%) Query: 47 IPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSY 106 IP++Y ++ V+G L N +V+ + V+++YI NLA+AD L + LP A + Sbjct: 47 IPLVYLVVCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNAL 106 Query: 107 RYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQR-RNPWQASYIVP 165 Y W FG +MC++ + +N F SIF +T MSVDRY +V++P S R R A + Sbjct: 107 SY-WPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSA 165 Query: 166 LVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLI 225 VW + + LP F V G++ C M + PE A W AG + LGF PL+ Sbjct: 166 AVWVASAVVVLPVVVFSGVPR----GMSTCHMQW-PEPAAAWRAGFIIYTAALGFFGPLL 220 Query: 226 FIATCYFGIRKHLLKTNSYG---------KNRITRDQVLKMAAAVVLAFIICWLPFHVLT 276 I CY I ++K S G + R + +V +M AVV F++CW+PF+VL Sbjct: 221 VICLCYLLI---VVKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLN 277 Query: 277 FLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVP 336 ++ + + + + + +ALP+A NSC NP LY F+ RF+Q R V P Sbjct: 278 IVNVVCPLPEEPAFFGLYFLVVALPYA------NSCANPILYGFLSYRFKQGFRRVLLRP 331 >gi|39725940 opioid receptor, kappa 1 [Homo sapiens] Length = 380 Score = 155 bits (393), Expect = 4e-38 Identities = 99/312 (31%), Positives = 162/312 (51%), Gaps = 19/312 (6%) Query: 46 AIPIL----YYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWA 101 AIP++ Y ++FV+G + N +V+ + K ++IYIFNLA+AD L+ T+P + Sbjct: 57 AIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQS 116 Query: 102 TYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLS-QRRNPWQA 160 T Y W FG V+CK+ S NMF SIF +T MSVDRY +V +P + R P +A Sbjct: 117 TVYLMN-SWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKA 175 Query: 161 SYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGF 220 I +W ++ + + E + V C + FP + Y+ W + + I F Sbjct: 176 KIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAF 235 Query: 221 IIPLIFIATCY----FGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLT 276 +IP++ I CY ++ L + S K+R R ++ ++ VV F++CW P H+ Sbjct: 236 VIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLR-RITRLVLVVVAVFVVCWTPIHIFI 294 Query: 277 FLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVP 336 ++AL +S ++ + F I LG+TNS +NP LY F+ F++ R F P Sbjct: 295 LVEALG--STSHSTAALS----SYYFCIALGYTNSSLNPILYAFLDENFKRCFRD-FCFP 347 Query: 337 ITWLQGKRESMS 348 + ++ +R+S S Sbjct: 348 LK-MRMERQSTS 358 >gi|14043044 chemokine (C-C motif) receptor 9 isoform B [Homo sapiens] Length = 357 Score = 155 bits (391), Expect = 7e-38 Identities = 90/323 (27%), Positives = 161/323 (49%), Gaps = 24/323 (7%) Query: 47 IPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSY 106 +P LY+++F++G L N +V+ ++ K ++ +++ NLA+ADLL L TLP WA + Sbjct: 39 LPPLYWLVFIVGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWA--IAA 96 Query: 107 RYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQ------A 160 W F MCKV S +N ++ + I C+SVDRY ++ + R + W+ + Sbjct: 97 ADQWKFQTFMCKVVNSMYKMNFYSCVLLIMCISVDRYIAIAQ---AMRAHTWREKRLLYS 153 Query: 161 SYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGF 220 + +W +A +P + ++ E G+ C M +P ++ + + + +K ILGF Sbjct: 154 KMVCFTIWVLAAALCIPEILYSQIK--EESGIAICTMVYPSDESTKLKSAVLTLKVILGF 211 Query: 221 IIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDA 280 +P + +A CY I L++ K++ LK+ V+ F++ P++ + + Sbjct: 212 FLPFVVMACCYTIIIHTLIQAKKSSKHK-----ALKVTITVLTVFVLSQFPYNCILLVQT 266 Query: 281 L-AWMGVINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFR----- 334 + A+ I++C V ID+ + F +SC+NP LY FVG RF++ L + Sbjct: 267 IDAYAMFISNCAVSTNIDICFQVTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCI 326 Query: 335 VPITWLQGKRESMSCRKSSSLRE 357 W+ R S + SS L E Sbjct: 327 SQAQWVSFTRREGSLKLSSMLLE 349 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.330 0.141 0.455 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,747,463 Number of Sequences: 37866 Number of extensions: 516879 Number of successful extensions: 2649 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 302 Number of HSP's successfully gapped in prelim test: 122 Number of HSP's that attempted gapping in prelim test: 1397 Number of HSP's gapped (non-prelim): 536 length of query: 363 length of database: 18,247,518 effective HSP length: 104 effective length of query: 259 effective length of database: 14,309,454 effective search space: 3706148586 effective search space used: 3706148586 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.9 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.