Guide to the Human Genome
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Search of human proteins with 229577354

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|229577354 IQ motif containing F1 [Homo sapiens]
         (205 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|229577354 IQ motif containing F1 [Homo sapiens]                    417   e-117
gi|222831628 IQ motif containing F5 [Homo sapiens]                    176   9e-45
gi|44662817 IQ motif containing F2 [Homo sapiens]                     156   1e-38
gi|254028213 IQ motif containing F6 [Homo sapiens]                    114   6e-26
gi|146261997 IQ motif containing F3 [Homo sapiens]                    102   2e-22
gi|124494247 myosin IC isoform b [Homo sapiens]                        46   2e-05
gi|124494238 myosin IC isoform a [Homo sapiens]                        46   2e-05
gi|124494240 myosin IC isoform c [Homo sapiens]                        46   2e-05
gi|156119615 myosin IXA [Homo sapiens]                                 45   6e-05
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     41   6e-04
gi|122937315 leucine-rich repeats and IQ motif containing 4 [Hom...    40   0.002
gi|20270345 spermatogenesis associated 17 [Homo sapiens]               39   0.002
gi|126116596 asp (abnormal spindle)-like, microcephaly associate...    38   0.005
gi|153945715 myosin VC [Homo sapiens]                                  37   0.012
gi|39753961 IQ motif containing GTPase activating protein 3 [Hom...    37   0.015
gi|215982794 myosin VA isoform 2 [Homo sapiens]                        36   0.020
gi|215982791 myosin VA isoform 1 [Homo sapiens]                        36   0.020
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]             35   0.034
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]             35   0.034
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]             35   0.034
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    35   0.045
gi|197313718 IQ motif containing G [Homo sapiens]                      35   0.058
gi|14165288 IQ motif containing G [Homo sapiens]                       35   0.058
gi|194328685 myosin IB isoform 1 [Homo sapiens]                        34   0.076
gi|44889481 myosin IB isoform 2 [Homo sapiens]                         34   0.076
gi|240120050 myosin IB isoform 1 [Homo sapiens]                        34   0.076
gi|21237808 SWI/SNF-related matrix-associated actin-dependent re...    34   0.076
gi|21237805 SWI/SNF-related matrix-associated actin-dependent re...    34   0.076
gi|194363725 SWI/SNF-related matrix-associated actin-dependent r...    34   0.076
gi|217035093 cyclic nucleotide gated channel alpha 1 isoform 1 [...    34   0.099

>gi|229577354 IQ motif containing F1 [Homo sapiens]
          Length = 205

 Score =  417 bits (1071), Expect = e-117
 Identities = 205/205 (100%), Positives = 205/205 (100%)

Query: 1   MEEKQPQKTKEPSKEDEPQQKEMPTHLSLGAESKAEAKTPVLVETQTVDNANEKSEKPPE 60
           MEEKQPQKTKEPSKEDEPQQKEMPTHLSLGAESKAEAKTPVLVETQTVDNANEKSEKPPE
Sbjct: 1   MEEKQPQKTKEPSKEDEPQQKEMPTHLSLGAESKAEAKTPVLVETQTVDNANEKSEKPPE 60

Query: 61  NQKKLSDKDTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEA 120
           NQKKLSDKDTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEA
Sbjct: 61  NQKKLSDKDTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEA 120

Query: 121 FSRKEWAAVTLQSQARMWRIRRRYCQVLNAVRIIQAYWRCRSCASRGFIKGQYRVTANQL 180
           FSRKEWAAVTLQSQARMWRIRRRYCQVLNAVRIIQAYWRCRSCASRGFIKGQYRVTANQL
Sbjct: 121 FSRKEWAAVTLQSQARMWRIRRRYCQVLNAVRIIQAYWRCRSCASRGFIKGQYRVTANQL 180

Query: 181 HLQLEILLDSGPCIVTECIPFSIKE 205
           HLQLEILLDSGPCIVTECIPFSIKE
Sbjct: 181 HLQLEILLDSGPCIVTECIPFSIKE 205


>gi|222831628 IQ motif containing F5 [Homo sapiens]
          Length = 148

 Score =  176 bits (447), Expect = 9e-45
 Identities = 84/144 (58%), Positives = 104/144 (72%)

Query: 62  QKKLSDKDTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEAF 121
           +K +  + + A  IQAWWRG LVRR LLHAAL A IIQCWWR +L K+L KRR+  LE +
Sbjct: 5   EKTIMTERSAAVFIQAWWRGMLVRRTLLHAALRAWIIQCWWRQVLEKLLAKRRRMVLEFY 64

Query: 122 SRKEWAAVTLQSQARMWRIRRRYCQVLNAVRIIQAYWRCRSCASRGFIKGQYRVTANQLH 181
            ++EWAAV LQS  RMW +R+RYC++LNAVRIIQ YWR  SC SR FI+G Y +  NQL+
Sbjct: 65  VQQEWAAVRLQSWVRMWCVRQRYCRLLNAVRIIQVYWRWHSCHSRVFIEGHYELKENQLN 124

Query: 182 LQLEILLDSGPCIVTECIPFSIKE 205
           +QLEI L    C V +CIP  +KE
Sbjct: 125 IQLEISLGLQACKVQQCIPLPLKE 148


>gi|44662817 IQ motif containing F2 [Homo sapiens]
          Length = 164

 Score =  156 bits (395), Expect = 1e-38
 Identities = 76/151 (50%), Positives = 104/151 (68%), Gaps = 4/151 (2%)

Query: 41  VLVETQTVDNANEKSEKPPENQKKLSDKDTVATK----IQAWWRGTLVRRALLHAALSAC 96
           +LV  + V+ + E      + Q+K+ +K  + TK    IQAWWRGTLVRR LLHAAL A 
Sbjct: 12  ILVIIEDVEESIEWKTLQKKKQQKIKEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAW 71

Query: 97  IIQCWWRLILSKILKKRRQAALEAFSRKEWAAVTLQSQARMWRIRRRYCQVLNAVRIIQA 156
           IIQCWWR+ LS++L+K+RQAAL A++ +E A + LQS  RMWR+R RYCQVLNA+ IIQ 
Sbjct: 72  IIQCWWRMTLSRVLEKKRQAALIAYATRERAVIKLQSLVRMWRVRWRYCQVLNAIYIIQG 131

Query: 157 YWRCRSCASRGFIKGQYRVTANQLHLQLEIL 187
           +W+C +C +   ++G   VTA  L   +EI+
Sbjct: 132 HWQCHNCQTCALLQGHCVVTATHLQFHIEII 162


>gi|254028213 IQ motif containing F6 [Homo sapiens]
          Length = 107

 Score =  114 bits (285), Expect = 6e-26
 Identities = 52/106 (49%), Positives = 76/106 (71%)

Query: 83  LVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEAFSRKEWAAVTLQSQARMWRIRR 142
           +VRR LL AAL A +IQCWWR + +K+L++RR+ AL  ++ +EWA V +Q+Q RMW+ RR
Sbjct: 1   MVRRTLLQAALRAWVIQCWWRSMQAKMLEQRRRLALRLYTCQEWAVVKVQAQVRMWQARR 60

Query: 143 RYCQVLNAVRIIQAYWRCRSCASRGFIKGQYRVTANQLHLQLEILL 188
           R+ Q   A  IIQ++WR  +  +RG I+G Y V A++L L +EIL+
Sbjct: 61  RFLQARQAACIIQSHWRWHASQTRGLIRGHYEVRASRLELDIEILM 106



 Score = 29.6 bits (65), Expect = 1.9
 Identities = 15/36 (41%), Positives = 19/36 (52%)

Query: 68  KDTVATKIQAWWRGTLVRRALLHAALSACIIQCWWR 103
           ++    K+QA  R    RR  L A  +ACIIQ  WR
Sbjct: 42  QEWAVVKVQAQVRMWQARRRFLQARQAACIIQSHWR 77


>gi|146261997 IQ motif containing F3 [Homo sapiens]
          Length = 154

 Score =  102 bits (255), Expect = 2e-22
 Identities = 52/116 (44%), Positives = 74/116 (63%)

Query: 72  ATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEAFSRKEWAAVTL 131
           A +IQAWWRG LVRR LL AAL A +IQCWWR ++ + +++RRQA L  +  +E A V L
Sbjct: 37  AGQIQAWWRGVLVRRTLLVAALRAWMIQCWWRTLVQRRIRQRRQALLRVYVIQEQATVKL 96

Query: 132 QSQARMWRIRRRYCQVLNAVRIIQAYWRCRSCASRGFIKGQYRVTANQLHLQLEIL 187
           QS  RMW+ R+ Y Q+ NA+ + Q      +  + GF++ QY + + Q    +EIL
Sbjct: 97  QSCIRMWQCRQCYRQMCNALCLFQVPESSLAFQTDGFLQVQYAIPSKQPEFHIEIL 152


>gi|124494247 myosin IC isoform b [Homo sapiens]
          Length = 1044

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 29/74 (39%), Positives = 41/74 (55%), Gaps = 10/74 (13%)

Query: 68  KDTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEAFSRKEWA 127
           + ++ATKIQA WRG   R+  L    SA  IQ WWR  L      RR+AA     +++WA
Sbjct: 715 RQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLG-----RRKAA-----KRKWA 764

Query: 128 AVTLQSQARMWRIR 141
           A T++   R + +R
Sbjct: 765 AQTIRRLIRGFVLR 778


>gi|124494238 myosin IC isoform a [Homo sapiens]
          Length = 1063

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 29/74 (39%), Positives = 41/74 (55%), Gaps = 10/74 (13%)

Query: 68  KDTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEAFSRKEWA 127
           + ++ATKIQA WRG   R+  L    SA  IQ WWR  L      RR+AA     +++WA
Sbjct: 734 RQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLG-----RRKAA-----KRKWA 783

Query: 128 AVTLQSQARMWRIR 141
           A T++   R + +R
Sbjct: 784 AQTIRRLIRGFVLR 797


>gi|124494240 myosin IC isoform c [Homo sapiens]
          Length = 1028

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 29/74 (39%), Positives = 41/74 (55%), Gaps = 10/74 (13%)

Query: 68  KDTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEAFSRKEWA 127
           + ++ATKIQA WRG   R+  L    SA  IQ WWR  L      RR+AA     +++WA
Sbjct: 699 RQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLG-----RRKAA-----KRKWA 748

Query: 128 AVTLQSQARMWRIR 141
           A T++   R + +R
Sbjct: 749 AQTIRRLIRGFVLR 762


>gi|156119615 myosin IXA [Homo sapiens]
          Length = 2548

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 32/87 (36%), Positives = 48/87 (55%), Gaps = 5/87 (5%)

Query: 75   IQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAAL--EAFSRKEWAAVTLQ 132
            +Q W+R  L R+  LH   ++ IIQ +WR  L++  K+ R AA+  +AF     AA  LQ
Sbjct: 1026 LQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQ--KQVRDAAVQKDAFVMAS-AAALLQ 1082

Query: 133  SQARMWRIRRRYCQVLNAVRIIQAYWR 159
            +  R    R+RY ++  A  +IQ  WR
Sbjct: 1083 ASWRAHLERQRYLELRAAAIVIQQKWR 1109



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 28/115 (24%), Positives = 51/115 (44%), Gaps = 17/115 (14%)

Query: 52   NEKSEKPPENQKKLSDKDTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILK 111
            N+K  +    QK      + A  +QA WR  L R+  L    +A +IQ  WR        
Sbjct: 1058 NQKQVRDAAVQKDAFVMASAAALLQASWRAHLERQRYLELRAAAIVIQQKWR-------- 1109

Query: 112  KRRQAALEAFSRKEWAAVTLQSQARMWRIRRRYCQVLNAVRIIQAYWRCRSCASR 166
                   + + R+  AA+ +Q++ + +R  +RY +    + ++Q+   CR   +R
Sbjct: 1110 -------DYYRRRHMAAICIQARWKAYRESKRYQEQRKKIILLQS--TCRGFRAR 1155


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 41.2 bits (95), Expect = 6e-04
 Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 2/78 (2%)

Query: 2   EEKQPQKTKEPSKEDEPQQKEMPTHLSLGAESKAEAKTPVLVETQTVDNAN--EKSEKPP 59
           E K P+K K P KE+     E  + +   A+S AE K+P   ++ T + A   EK++ P 
Sbjct: 597 EAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPE 656

Query: 60  ENQKKLSDKDTVATKIQA 77
           + + K  +K     K +A
Sbjct: 657 KEEAKSPEKAKSPVKAEA 674



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 22/76 (28%), Positives = 39/76 (51%), Gaps = 4/76 (5%)

Query: 2   EEKQPQKTKEPSKEDEPQQKEMPTHLSLGAESKAEAKTPVLVETQTVDNANEKSEKPPEN 61
           E K P+K K P KE+    ++  + +   A+S  +AK+PV  E +    + EK++ P + 
Sbjct: 645 EAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAK----SPEKAKSPVKE 700

Query: 62  QKKLSDKDTVATKIQA 77
           + K  +K     K +A
Sbjct: 701 EAKSPEKAKSPVKEEA 716



 Score = 38.1 bits (87), Expect = 0.005
 Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 3/76 (3%)

Query: 2   EEKQPQKTKEPSKEDEPQQKEMPTHLSLGAESKAEAKTPVLVETQTVDNAN---EKSEKP 58
           E K P+K K P KE+    ++  + +   A+S  +AK+PV  E +T + A    ++  K 
Sbjct: 687 EAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKS 746

Query: 59  PENQKKLSDKDTVATK 74
           PE  K      T+  K
Sbjct: 747 PEKAKSPEKAKTLDVK 762



 Score = 36.2 bits (82), Expect = 0.020
 Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 8/84 (9%)

Query: 2   EEKQPQKTKEPSKED--EPQQKEMP----THLSLGAESKAEAKTPVLVETQTVDNAN--E 53
           E K P+K K P+KE+   P + + P    + +   A+S AEAK+PV  E ++       E
Sbjct: 577 EVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPE 636

Query: 54  KSEKPPENQKKLSDKDTVATKIQA 77
           K++ P + + K  +K     K +A
Sbjct: 637 KAKSPTKEEAKSPEKAKSPEKEEA 660



 Score = 35.8 bits (81), Expect = 0.026
 Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 1/63 (1%)

Query: 2   EEKQPQKTKEPSKEDEPQQKEMPTHLSLGAESKAEAKTPVLVETQTVDNANEKSE-KPPE 60
           E K P+K K P+KE+     E  +     A+S AE K+P   ++   + A   +E K PE
Sbjct: 543 EVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPE 602

Query: 61  NQK 63
             K
Sbjct: 603 KAK 605



 Score = 35.0 bits (79), Expect = 0.045
 Identities = 22/86 (25%), Positives = 40/86 (46%), Gaps = 10/86 (11%)

Query: 2   EEKQPQKTKEPSKEDEPQQKEMPTHLSLGAESKAEAKTPVLVETQTVDNAN--------- 52
           E K P+K K P K +    ++  + +   A+S  +AK+PV  E ++ + A          
Sbjct: 659 EAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKS 718

Query: 53  -EKSEKPPENQKKLSDKDTVATKIQA 77
            EK++ P + + K  +K     K +A
Sbjct: 719 PEKAKSPVKEEAKTPEKAKSPVKEEA 744



 Score = 34.7 bits (78), Expect = 0.058
 Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 2/78 (2%)

Query: 2   EEKQPQKTKEPSKED-EPQQKEMPTHLSLGAESKAEAK-TPVLVETQTVDNANEKSEKPP 59
           E K P+K K P KED +  +KE+P    + +  K E K   V V+        EK+   P
Sbjct: 792 EVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATP 851

Query: 60  ENQKKLSDKDTVATKIQA 77
           + ++K   K   A K +A
Sbjct: 852 KTEEKKDSKKEEAPKKEA 869



 Score = 33.1 bits (74), Expect = 0.17
 Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 11/74 (14%)

Query: 2   EEKQPQKTKEPSKED--EPQQKEMPTHLSLGAESKAEAKTPVLVETQTVDNA-NEKSEKP 58
           E K P+K K P KE+   P++ + P         K EAKTP   ++   + A + +  K 
Sbjct: 701 EAKSPEKAKSPVKEEAKSPEKAKSPV--------KEEAKTPEKAKSPVKEEAKSPEKAKS 752

Query: 59  PENQKKLSDKDTVA 72
           PE  K L  K   A
Sbjct: 753 PEKAKTLDVKSPEA 766



 Score = 32.7 bits (73), Expect = 0.22
 Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 1/63 (1%)

Query: 2   EEKQPQKTKEPSKEDEPQQKEMPTHLSLGAESKAEAKTPVLVETQTVDNANEKSE-KPPE 60
           E K P + K P KE+     E+ +     + +K EAK+P   ++   + A   +E K PE
Sbjct: 523 EAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPE 582

Query: 61  NQK 63
             K
Sbjct: 583 KAK 585



 Score = 32.3 bits (72), Expect = 0.29
 Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 2/72 (2%)

Query: 2   EEKQPQKTKEPSKEDEPQQKEMPTHLSLGAESKAEAKTPVLVET--QTVDNANEKSEKPP 59
           E K P + K P K   P ++E  +     +  K EAK+P  V++  +    A E+++ P 
Sbjct: 537 EAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPA 596

Query: 60  ENQKKLSDKDTV 71
           E +     K  V
Sbjct: 597 EAKSPEKAKSPV 608



 Score = 31.6 bits (70), Expect = 0.49
 Identities = 24/84 (28%), Positives = 37/84 (44%), Gaps = 17/84 (20%)

Query: 2   EEKQPQKTKEPSKED--EPQQKEMPTHLSLGAESKA--------------EAKTPVLVET 45
           E K P+K K P KE+   P++ + P      +  KA              EAKTP   E 
Sbjct: 715 EAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEA 774

Query: 46  QT-VDNANEKSEKPPENQKKLSDK 68
           ++  D   EK++ P + + K  +K
Sbjct: 775 RSPADKFPEKAKSPVKEEVKSPEK 798



 Score = 30.0 bits (66), Expect = 1.4
 Identities = 17/63 (26%), Positives = 30/63 (47%), Gaps = 6/63 (9%)

Query: 2   EEKQPQKTKEPSKEDEPQQKEMPTHLSLGAESKAEAKTPVLVETQTVDNANEKSEKPPEN 61
           E K P + K P KE+     E+ +     + +K EAK+P   ++       EK++ P + 
Sbjct: 557 EAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSP------EKAKSPVKE 610

Query: 62  QKK 64
           + K
Sbjct: 611 EAK 613



 Score = 29.3 bits (64), Expect = 2.4
 Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 12/76 (15%)

Query: 2   EEKQPQKTKEPSKEDEPQQKEMPTHLSLGAESKAEAKTPVLVETQTVDNANEKSEKPPEN 61
           E K P + K P K   P ++E        A+S  +AK+P   E +    + EK++ P + 
Sbjct: 625 EAKSPAEVKSPEKAKSPTKEE--------AKSPEKAKSPEKEEAK----SPEKAKSPVKA 672

Query: 62  QKKLSDKDTVATKIQA 77
           + K  +K     K +A
Sbjct: 673 EAKSPEKAKSPVKAEA 688



 Score = 27.7 bits (60), Expect = 7.1
 Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 5/60 (8%)

Query: 2   EEKQPQK-TKEPSKEDEPQQKEMPTHLSLGAESKAEAKTPVLVETQTVDNANEKSEKPPE 60
           E   P+K  K P KE+     E  +     A+S AE K+P   ++     A E+++ PPE
Sbjct: 508 EAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSP----AKEEAKSPPE 563



 Score = 27.3 bits (59), Expect = 9.3
 Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 3/61 (4%)

Query: 7   QKTKEPSKEDEPQ-QKEMPTHLSLGAESKAEAKTPVLVETQTVDNAN--EKSEKPPENQK 63
           ++TK P  E+    +KE  + +   A+S AEAK+P   E ++       EK++ P + + 
Sbjct: 499 EETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEA 558

Query: 64  K 64
           K
Sbjct: 559 K 559


>gi|122937315 leucine-rich repeats and IQ motif containing 4 [Homo
           sapiens]
          Length = 560

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 9/86 (10%)

Query: 5   QPQKTKEPSKEDEPQQKEMPTHLSLGAESKAEAKTPVLVETQTVDNANEKSEKPPEN--- 61
           Q Q  KE   ED      + THL    +S    K   L++    +   E   +  E    
Sbjct: 442 QAQALKELRLEDN-----LLTHLPENLDSLVNLKVLTLMDNPMEEPPKEVCAEGNEAIWK 496

Query: 62  -QKKLSDKDTVATKIQAWWRGTLVRR 86
             K+  +++ +ATKIQAWWRGT+V+R
Sbjct: 497 YLKENRNRNIMATKIQAWWRGTMVQR 522


>gi|20270345 spermatogenesis associated 17 [Homo sapiens]
          Length = 361

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 9/81 (11%)

Query: 68  KDTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEA------F 121
           ++  A KIQ+W+RG  VR  + H      IIQ WWR  L    +K+ Q  ++        
Sbjct: 32  ENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLG---RKQYQLTVQVAYYTMMM 88

Query: 122 SRKEWAAVTLQSQARMWRIRR 142
           +     AV +Q + R +R+R+
Sbjct: 89  NLYNAMAVRIQRRWRGYRVRK 109



 Score = 27.3 bits (59), Expect = 9.3
 Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 1/47 (2%)

Query: 114 RQAALEAFSRKEW-AAVTLQSQARMWRIRRRYCQVLNAVRIIQAYWR 159
           R + ++ F +KE  AAV +QS  R  ++R     +   V IIQ +WR
Sbjct: 21  RNSVVDPFRKKENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWR 67


>gi|126116596 asp (abnormal spindle)-like, microcephaly associated
            [Homo sapiens]
          Length = 3477

 Score = 38.1 bits (87), Expect = 0.005
 Identities = 29/104 (27%), Positives = 55/104 (52%), Gaps = 15/104 (14%)

Query: 60   ENQKKLSDKDTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALE 119
            ++++ L+ K T A KIQ+ +RG  VRR + H   +A  I+  +++  S+I          
Sbjct: 2086 QHKEYLNLKKT-AIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRI---------- 2134

Query: 120  AFSRKEWAAVTLQSQARMW----RIRRRYCQVLNAVRIIQAYWR 159
            ++     AA+ +Q + R +      R +Y  +L AV+++QA +R
Sbjct: 2135 SYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFR 2178



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 33/137 (24%), Positives = 61/137 (44%), Gaps = 17/137 (12%)

Query: 63   KKLSDKDTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAA----- 117
            +K + ++  A  IQ+W+R     R  ++      IIQ  +R   ++ L KRR+ +     
Sbjct: 1459 RKQAKEENSAIIIQSWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRRKESILTIQ 1518

Query: 118  ----------LEAFSRKEWAAVTLQSQARMWRIR-RRYCQVLNAVRIIQAYWRCRSCASR 166
                      +E  +  +  A  +Q QA   R++    C+ + A  +IQ+YWR R    R
Sbjct: 1519 KYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVR 1578

Query: 167  GFIKGQYRVTANQLHLQ 183
             F+  +  +   Q H++
Sbjct: 1579 -FLNLKKTIIKFQAHVR 1594



 Score = 36.6 bits (83), Expect = 0.015
 Identities = 29/107 (27%), Positives = 48/107 (44%), Gaps = 19/107 (17%)

Query: 62   QKKLSDKDTVATKIQAWWRGTLVRRALLHAAL---------SACIIQCWWRLILSKILKK 112
            +++L  +   A  IQ +WR  L +R LL             +A +IQ +WR         
Sbjct: 1309 KQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWR--------- 1359

Query: 113  RRQAALEAFSRKEWAAVTLQSQARMWRIRRRYCQVLNAVRIIQAYWR 159
             R +  + F + ++ ++ LQS+ RM      Y + L A   IQ +WR
Sbjct: 1360 -RYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWR 1405



 Score = 36.2 bits (82), Expect = 0.020
 Identities = 31/102 (30%), Positives = 48/102 (47%), Gaps = 17/102 (16%)

Query: 75   IQAWWRGTLVRRALLHAALSACIIQCWWRLILS----KILKKRR---QAALEAFS----- 122
            +Q+ W+G  +RR L      A IIQ ++R+ +     KI+KK     Q    A+S     
Sbjct: 1954 LQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQ 2013

Query: 123  -----RKEWAAVTLQSQARMWRIRRRYCQVLNAVRIIQAYWR 159
                 + + A VTLQS  R  ++R+R      A   IQ+ +R
Sbjct: 2014 NHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYR 2055



 Score = 35.0 bits (79), Expect = 0.045
 Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 6/100 (6%)

Query: 60   ENQKKLSDKDTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALE 119
            + ++ L    + AT IQ+ +R  LVRR  +    +   +Q  +R   + I  K +   L 
Sbjct: 2399 KTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYR---ATICAKHK---LY 2452

Query: 120  AFSRKEWAAVTLQSQARMWRIRRRYCQVLNAVRIIQAYWR 159
             F     AA+T+QS  R   ++++  ++  A  +IQA +R
Sbjct: 2453 QFLHLRKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFR 2492



 Score = 35.0 bits (79), Expect = 0.045
 Identities = 36/131 (27%), Positives = 50/131 (38%), Gaps = 27/131 (20%)

Query: 63   KKLSDKDTVATKIQAWWR-----------------------GTLVRRALLHAALSACIIQ 99
            KK   K   A KIQAW+R                         L R   L+   SA IIQ
Sbjct: 2949 KKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQ 3008

Query: 100  CWWRLILSKILKKRRQAALEAFSRKEWAAVTLQSQARMWRIRRRYCQVLNAVRIIQAYWR 159
              WR IL   +       +    ++  AA  +Q+  R ++ R+ + +  +A  IIQ Y R
Sbjct: 3009 RKWRAILPAKIAHEHFLMI----KRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIR 3064

Query: 160  CRSCASRGFIK 170
             R       IK
Sbjct: 3065 AREAGKHERIK 3075



 Score = 34.7 bits (78), Expect = 0.058
 Identities = 25/81 (30%), Positives = 35/81 (43%), Gaps = 11/81 (13%)

Query: 75   IQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEAFSRKEWAAVTLQSQ 134
            IQA  +G + +R       S   IQ  WR   +K            +  K  AA  +Q+ 
Sbjct: 2916 IQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAK-----------KYLCKVKAACKIQAW 2964

Query: 135  ARMWRIRRRYCQVLNAVRIIQ 155
             R WR  + Y  +L AV+IIQ
Sbjct: 2965 YRCWRAHKEYLAILKAVKIIQ 2985



 Score = 34.3 bits (77), Expect = 0.076
 Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 7/88 (7%)

Query: 72   ATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEAFSRKEWAAVTL 131
            AT IQ  +R  ++RR  L    +A +IQ  +R  L    K   Q     F + + A + +
Sbjct: 2266 ATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCT--KHHLQ-----FLQVQNAVIKI 2318

Query: 132  QSQARMWRIRRRYCQVLNAVRIIQAYWR 159
            QS  R W IR+R  ++  A   IQ+ +R
Sbjct: 2319 QSSYRRWMIRKRMREMHRAATFIQSTFR 2346



 Score = 33.9 bits (76), Expect = 0.099
 Identities = 25/89 (28%), Positives = 49/89 (55%), Gaps = 14/89 (15%)

Query: 75   IQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEAFSRKEWAAVTLQSQ 134
            IQ+++RG  VR+ + +   +A +IQ ++R+  +K+           +  K+ A V +Q+ 
Sbjct: 2672 IQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKV----------DYETKKTAIVVIQNY 2721

Query: 135  ARMW-RI---RRRYCQVLNAVRIIQAYWR 159
             R++ R+   R+ +  V  +VR IQA +R
Sbjct: 2722 YRLYVRVKTERKNFLAVQKSVRTIQAAFR 2750



 Score = 33.1 bits (74), Expect = 0.17
 Identities = 23/98 (23%), Positives = 51/98 (52%), Gaps = 6/98 (6%)

Query: 62   QKKLSDKDTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEAF 121
            +++   +   A  +Q ++R    R+  L    +A ++Q  +R  LS   K +RQ  L+  
Sbjct: 2853 RRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSA--KHQRQVYLQIR 2910

Query: 122  SRKEWAAVTLQSQARMWRIRRRYCQVLNAVRIIQAYWR 159
            S    + + +Q++++ +  +R++ ++ N+   IQA WR
Sbjct: 2911 S----SVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWR 2944



 Score = 32.7 bits (73), Expect = 0.22
 Identities = 31/132 (23%), Positives = 52/132 (39%), Gaps = 41/132 (31%)

Query: 68   KDTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKI------------------ 109
            K   A ++QA +R  L    L     +AC+IQ +WR+   ++                  
Sbjct: 1537 KRAAAIQLQAAFR-RLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRK 1595

Query: 110  ------LKKRRQAA----------------LEAFSRKEWAAVTLQSQARMWRIRRRYCQV 147
                   KK ++AA                L ++ +   A + LQS  R  + R+ Y  +
Sbjct: 1596 HQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQARKMYIHI 1655

Query: 148  LNAVRIIQAYWR 159
            L +V  IQ+Y+R
Sbjct: 1656 LTSVIKIQSYYR 1667



 Score = 32.7 bits (73), Expect = 0.22
 Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 6/98 (6%)

Query: 62   QKKLSDKDTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEAF 121
            +K++ D +  A  IQ+ +R    ++       SA IIQ W+R I  KI   + +  L   
Sbjct: 2037 RKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGI--KITNHQHKEYLNL- 2093

Query: 122  SRKEWAAVTLQSQARMWRIRRRYCQVLNAVRIIQAYWR 159
               +  A+ +QS  R  R+RR    +  A   I+A ++
Sbjct: 2094 ---KKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFK 2128



 Score = 32.3 bits (72), Expect = 0.29
 Identities = 32/121 (26%), Positives = 55/121 (45%), Gaps = 18/121 (14%)

Query: 57   KPPENQKK-LSDKDTVATKIQAWWRGTLVRRALLHAALSACIIQCWWR---------LIL 106
            K   NQ+K        AT +QA +RG  VR+ +   +++A  IQ  +R          +L
Sbjct: 1789 KAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVL 1848

Query: 107  SKILKKRR--------QAALEAFSRKEWAAVTLQSQARMWRIRRRYCQVLNAVRIIQAYW 158
              I+K +R              F + + A ++LQS  R W++R++  +   A   IQ+ +
Sbjct: 1849 QSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALKIQSAF 1908

Query: 159  R 159
            R
Sbjct: 1909 R 1909



 Score = 32.0 bits (71), Expect = 0.38
 Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 21/117 (17%)

Query: 61   NQKKLSDKDTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQA---- 116
            ++K+         K+Q+  +    R+  LH   +A  IQ  +R    KI  ++R+     
Sbjct: 1671 SKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRS--KKIAAQKREEYMQM 1728

Query: 117  -----ALEAFSR----------KEWAAVTLQSQARMWRIRRRYCQVLNAVRIIQAYW 158
                  L+AF R          +  A ++LQS  RM + R+ Y ++  A+ +IQ Y+
Sbjct: 1729 RESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYY 1785



 Score = 31.6 bits (70), Expect = 0.49
 Identities = 37/159 (23%), Positives = 65/159 (40%), Gaps = 30/159 (18%)

Query: 60   ENQKKLSDKDTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKR------ 113
            E  +K+ +K   A+ IQ +WR    R+  L     + I+Q   R+I++    KR      
Sbjct: 1341 EKLEKVQNK--AASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATV 1398

Query: 114  -----------RQAALEAFSRKEWAAVTLQSQARMWRIRRRYCQVLNAVRIIQAY--WRC 160
                       R+   + +   + + + +QS  R W+ R+   QV   V + +A+  W  
Sbjct: 1399 TIQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQRKMQSQVKATVILQRAFREWHL 1458

Query: 161  RSCA----SRGFIKGQYRVTANQLHLQLEILLDSGPCIV 195
            R  A    S   I+  YR     +H +L   +    C+V
Sbjct: 1459 RKQAKEENSAIIIQSWYR-----MHKELRKYIYIRSCVV 1492



 Score = 31.6 bits (70), Expect = 0.49
 Identities = 31/104 (29%), Positives = 44/104 (42%), Gaps = 26/104 (25%)

Query: 72   ATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEAFSRKEW--AAV 129
            A  IQA +RG   R+  L    +A IIQ        K ++ R     E     E+  + V
Sbjct: 3033 ACLIQAHYRGYKGRQVFLRQKSAALIIQ--------KYIRAREAGKHERIKYIEFKKSTV 3084

Query: 130  TLQSQARMWRIRRRYCQV----------------LNAVRIIQAY 157
             LQ+  R W +R+R+ +                 LNAVRI +AY
Sbjct: 3085 ILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAY 3128



 Score = 30.0 bits (66), Expect = 1.4
 Identities = 16/47 (34%), Positives = 28/47 (59%)

Query: 114  RQAALEAFSRKEWAAVTLQSQARMWRIRRRYCQVLNAVRIIQAYWRC 160
            R+  L   +++E +A+ +QS  RM +  R+Y  + + V IIQ  +RC
Sbjct: 1454 REWHLRKQAKEENSAIIIQSWYRMHKELRKYIYIRSCVVIIQKRFRC 1500



 Score = 30.0 bits (66), Expect = 1.4
 Identities = 24/96 (25%), Positives = 41/96 (42%), Gaps = 8/96 (8%)

Query: 72   ATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSK--------ILKKRRQAALEAFSR 123
            A +IQ  ++  L  +       S   IQ W+R  L +         +KK      E  S+
Sbjct: 3121 AVRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQ 3180

Query: 124  KEWAAVTLQSQARMWRIRRRYCQVLNAVRIIQAYWR 159
            +  AA  +Q   R + +R++  +  + +  IQA WR
Sbjct: 3181 RNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWR 3216



 Score = 29.3 bits (64), Expect = 2.4
 Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 7/66 (10%)

Query: 94   SACIIQCWWRLILSKILKKRRQAALEAFSRKEWAAVTLQSQARMWRIRRRYCQVLNAVRI 153
            +A +IQ  WR    K   KR Q        +E AA  +Q     +  ++R  + +NA  +
Sbjct: 1269 AARLIQTTWRKYKLKTDLKRHQ-------EREKAARIIQLAVINFLAKQRLRKRVNAALV 1321

Query: 154  IQAYWR 159
            IQ YWR
Sbjct: 1322 IQKYWR 1327



 Score = 29.3 bits (64), Expect = 2.4
 Identities = 24/101 (23%), Positives = 51/101 (50%), Gaps = 16/101 (15%)

Query: 75   IQAWWRGTLV---RRALLHAALSACI-IQCWWRLILSKILKKRRQAALEA---------- 120
            IQ W++ + +   + A  H+   A + IQ  +  ++++ L+ ++ AAL            
Sbjct: 2794 IQEWYKASGLACSQEAEYHSQSRAAVTIQKAFCRMVTRKLETQKCAALRIQFFLQMAVYR 2853

Query: 121  --FSRKEWAAVTLQSQARMWRIRRRYCQVLNAVRIIQAYWR 159
              F +++ AA+TLQ   R W+ R+++     A  ++Q ++R
Sbjct: 2854 RRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYR 2894



 Score = 28.9 bits (63), Expect = 3.2
 Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 3/81 (3%)

Query: 110  LKKRRQAALEAFSRKEWAAVTLQSQARMWRIRRRYCQVLNAVRIIQAYWRCRSCASRGFI 169
            L+KR  AAL    +K W  V  Q +  M +  +       A  +IQ YWR  S   R F+
Sbjct: 1312 LRKRVNAALVI--QKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQR-FL 1368

Query: 170  KGQYRVTANQLHLQLEILLDS 190
            K +Y     Q  +++ I + S
Sbjct: 1369 KLKYYSIILQSRIRMIIAVTS 1389



 Score = 27.7 bits (60), Expect = 7.1
 Identities = 22/85 (25%), Positives = 39/85 (45%), Gaps = 6/85 (7%)

Query: 75   IQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEAFSRKEWAAVTLQSQ 134
            +QA +RG  VRR L     +A +IQ  +R    +    + +   +   ++ WA      Q
Sbjct: 2173 LQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYWAMKERNIQ 2232

Query: 135  ARMWRIRRRYCQVLNAVRIIQAYWR 159
                   +RY ++ ++V  IQA +R
Sbjct: 2233 F------QRYNKLRHSVIYIQAIFR 2251


>gi|153945715 myosin VC [Homo sapiens]
          Length = 1742

 Score = 37.0 bits (84), Expect = 0.012
 Identities = 32/102 (31%), Positives = 51/102 (50%), Gaps = 15/102 (14%)

Query: 75  IQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEAFSRKE-WAAVTLQS 133
           +Q   RG L R+  L    +A IIQ ++R       ++  + A+ A + KE WAA+ +Q 
Sbjct: 763 VQKHMRGWLQRKKFLRERRAALIIQQYFRG------QQTVRKAITAVALKEAWAAIIIQK 816

Query: 134 QARMWRIRRRYCQVLNAVRIIQAYWRCRSCASRGFI-KGQYR 174
             R + +R  Y  +  A   +QAY       SRGF+ + +YR
Sbjct: 817 HCRGYLVRSLYQLIRMATITMQAY-------SRGFLARRRYR 851



 Score = 34.3 bits (77), Expect = 0.076
 Identities = 38/118 (32%), Positives = 55/118 (46%), Gaps = 20/118 (16%)

Query: 62  QKKLSDKDTVATKIQAWWRGT-LVRRALLHAAL----SACIIQCWWRLILSKILKKRRQA 116
           +KK   +   A  IQ ++RG   VR+A+   AL    +A IIQ   R  L + L +  + 
Sbjct: 773 RKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRM 832

Query: 117 A---LEAFSR------------KEWAAVTLQSQARMWRIRRRYCQVLNAVRIIQAYWR 159
           A   ++A+SR            +E  AV LQ  AR W  RRR+  +   V  IQ  +R
Sbjct: 833 ATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYR 890


>gi|39753961 IQ motif containing GTPase activating protein 3 [Homo
           sapiens]
          Length = 1631

 Score = 36.6 bits (83), Expect = 0.015
 Identities = 38/128 (29%), Positives = 57/128 (44%), Gaps = 23/128 (17%)

Query: 74  KIQAWWRGTLVRRAL------LHAALSACI-IQCWWRLILSKILKKRRQAALEAFSRKEW 126
           ++QA  RG LVR+        L   L A I IQ  WR    +   K     L+ F     
Sbjct: 736 QLQARLRGFLVRQKFAEHSHFLRTWLPAVIKIQAHWRGYRQR---KIYLEWLQYFKANLD 792

Query: 127 AAVTLQSQARMWRIRRRYCQVL-------NAVRIIQAYWRCRSCASRGFIKGQYRVTANQ 179
           A + +Q+ ARMW  RR+Y + L       N++  IQA++R R        +  YR+  + 
Sbjct: 793 AIIKIQAWARMWAARRQYLRRLHYFQKNVNSIVKIQAFFRARKA------QDDYRILVHA 846

Query: 180 LHLQLEIL 187
            H  L ++
Sbjct: 847 PHPPLSVV 854


>gi|215982794 myosin VA isoform 2 [Homo sapiens]
          Length = 1828

 Score = 36.2 bits (82), Expect = 0.020
 Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 9/127 (7%)

Query: 64  KLSDKDTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEAFSR 123
           K   +   AT IQ +WR  +VRR       +  ++Q + R  L+   + R +  L     
Sbjct: 810 KFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLA---RNRYRKIL----- 861

Query: 124 KEWAAVTLQSQARMWRIRRRYCQVLNAVRIIQAYWRCRSCASRGFIKGQYRVTANQLHLQ 183
           +E  AV +Q + R W  R  Y + ++A+  +Q  +R R  A R   K +    + + + +
Sbjct: 862 REHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFR-RMMAKRELKKLKIEARSVERYKK 920

Query: 184 LEILLDS 190
           L I +++
Sbjct: 921 LHIGMEN 927



 Score = 33.1 bits (74), Expect = 0.17
 Identities = 30/99 (30%), Positives = 47/99 (47%), Gaps = 9/99 (9%)

Query: 62  QKKLSDKDTVAT-KIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEA 120
           +K  +DK   A  +IQ   RG L+R+  L    +A  +Q + R   ++   K        
Sbjct: 759 EKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAK-------- 810

Query: 121 FSRKEWAAVTLQSQARMWRIRRRYCQVLNAVRIIQAYWR 159
           F R+  AA  +Q   RM+ +RRRY     A  ++Q+Y R
Sbjct: 811 FLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLR 849


>gi|215982791 myosin VA isoform 1 [Homo sapiens]
          Length = 1855

 Score = 36.2 bits (82), Expect = 0.020
 Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 9/127 (7%)

Query: 64  KLSDKDTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEAFSR 123
           K   +   AT IQ +WR  +VRR       +  ++Q + R  L+   + R +  L     
Sbjct: 810 KFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLA---RNRYRKIL----- 861

Query: 124 KEWAAVTLQSQARMWRIRRRYCQVLNAVRIIQAYWRCRSCASRGFIKGQYRVTANQLHLQ 183
           +E  AV +Q + R W  R  Y + ++A+  +Q  +R R  A R   K +    + + + +
Sbjct: 862 REHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFR-RMMAKRELKKLKIEARSVERYKK 920

Query: 184 LEILLDS 190
           L I +++
Sbjct: 921 LHIGMEN 927



 Score = 33.1 bits (74), Expect = 0.17
 Identities = 30/99 (30%), Positives = 47/99 (47%), Gaps = 9/99 (9%)

Query: 62  QKKLSDKDTVAT-KIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEA 120
           +K  +DK   A  +IQ   RG L+R+  L    +A  +Q + R   ++   K        
Sbjct: 759 EKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAK-------- 810

Query: 121 FSRKEWAAVTLQSQARMWRIRRRYCQVLNAVRIIQAYWR 159
           F R+  AA  +Q   RM+ +RRRY     A  ++Q+Y R
Sbjct: 811 FLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLR 849


>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 35.4 bits (80), Expect = 0.034
 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 11/74 (14%)

Query: 1   MEEKQPQKTKEPSKEDEPQQKEMPTHLSLGAESKAEAKTPVLVETQTVDNANEKSEKPPE 60
           + E+Q ++ KE  +++E +QK         A+ K EA+   + E Q    A E+ EK   
Sbjct: 482 LRERQQEEQKEKLRKEEQEQK---------AKKKQEAEENEITEKQ--QKAKEEMEKKES 530

Query: 61  NQKKLSDKDTVATK 74
            Q K  DK+T A +
Sbjct: 531 EQAKKEDKETSAKR 544


>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 35.4 bits (80), Expect = 0.034
 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 11/74 (14%)

Query: 1   MEEKQPQKTKEPSKEDEPQQKEMPTHLSLGAESKAEAKTPVLVETQTVDNANEKSEKPPE 60
           + E+Q ++ KE  +++E +QK         A+ K EA+   + E Q    A E+ EK   
Sbjct: 482 LRERQQEEQKEKLRKEEQEQK---------AKKKQEAEENEITEKQ--QKAKEEMEKKES 530

Query: 61  NQKKLSDKDTVATK 74
            Q K  DK+T A +
Sbjct: 531 EQAKKEDKETSAKR 544


>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 35.4 bits (80), Expect = 0.034
 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 11/74 (14%)

Query: 1   MEEKQPQKTKEPSKEDEPQQKEMPTHLSLGAESKAEAKTPVLVETQTVDNANEKSEKPPE 60
           + E+Q ++ KE  +++E +QK         A+ K EA+   + E Q    A E+ EK   
Sbjct: 482 LRERQQEEQKEKLRKEEQEQK---------AKKKQEAEENEITEKQ--QKAKEEMEKKES 530

Query: 61  NQKKLSDKDTVATK 74
            Q K  DK+T A +
Sbjct: 531 EQAKKEDKETSAKR 544


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 35.0 bits (79), Expect = 0.045
 Identities = 17/63 (26%), Positives = 31/63 (49%)

Query: 15  EDEPQQKEMPTHLSLGAESKAEAKTPVLVETQTVDNANEKSEKPPENQKKLSDKDTVATK 74
           +DE  QK+ P    +  ++KA    P   ++   D+ +   ++PP+NQK      TV  +
Sbjct: 136 DDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQ 195

Query: 75  IQA 77
            +A
Sbjct: 196 TKA 198



 Score = 28.1 bits (61), Expect = 5.5
 Identities = 19/74 (25%), Positives = 34/74 (45%), Gaps = 7/74 (9%)

Query: 2   EEKQPQKTKEPSKEDEPQQKEMPTHLSLGAE---SKAEAKTPVLVETQTVDNANEKSEKP 58
           E+K+P K K       P     P   SLG +      E + PV    ++ ++++++S+  
Sbjct: 277 EQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPV----ESSEDSSDESDSS 332

Query: 59  PENQKKLSDKDTVA 72
            E +KK   K  V+
Sbjct: 333 SEEEKKPPTKAVVS 346


>gi|197313718 IQ motif containing G [Homo sapiens]
          Length = 443

 Score = 34.7 bits (78), Expect = 0.058
 Identities = 25/92 (27%), Positives = 45/92 (48%), Gaps = 5/92 (5%)

Query: 1   MEEKQPQKTKEPSKEDEPQQKEMPTHLSLGAESKAE----AKTPVLVETQTVDNANEKSE 56
           +EE+     ++  K+ E +Q E+    +  A   A     AK     E   +++  EK  
Sbjct: 323 LEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKER 382

Query: 57  KPPENQKKLSDKDTVATKIQAWWRGTLVRRAL 88
              + ++ L +  +V  K+QAWWRGT++RR +
Sbjct: 383 SKKKVKQDLLELKSVI-KLQAWWRGTMIRREI 413


>gi|14165288 IQ motif containing G [Homo sapiens]
          Length = 443

 Score = 34.7 bits (78), Expect = 0.058
 Identities = 25/92 (27%), Positives = 45/92 (48%), Gaps = 5/92 (5%)

Query: 1   MEEKQPQKTKEPSKEDEPQQKEMPTHLSLGAESKAE----AKTPVLVETQTVDNANEKSE 56
           +EE+     ++  K+ E +Q E+    +  A   A     AK     E   +++  EK  
Sbjct: 323 LEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKER 382

Query: 57  KPPENQKKLSDKDTVATKIQAWWRGTLVRRAL 88
              + ++ L +  +V  K+QAWWRGT++RR +
Sbjct: 383 SKKKVKQDLLELKSVI-KLQAWWRGTMIRREI 413


>gi|194328685 myosin IB isoform 1 [Homo sapiens]
          Length = 1136

 Score = 34.3 bits (77), Expect = 0.076
 Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 20/98 (20%)

Query: 69  DTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEAFSRKEWAA 128
           + +AT IQ  +RG   R   L    S  +I  W+          RR A  + + + + +A
Sbjct: 705 EDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWY----------RRYAQQKRYQQTKSSA 754

Query: 129 VTLQSQARMWRIRR--------RYCQVLNAVRIIQAYW 158
           + +QS  R W+ R+        + C+   AV  I AYW
Sbjct: 755 LVIQSYIRGWKARKILRELKHQKRCK--EAVTTIAAYW 790


>gi|44889481 myosin IB isoform 2 [Homo sapiens]
          Length = 1078

 Score = 34.3 bits (77), Expect = 0.076
 Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 20/98 (20%)

Query: 69  DTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEAFSRKEWAA 128
           + +AT IQ  +RG   R   L    S  +I  W+          RR A  + + + + +A
Sbjct: 705 EDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWY----------RRYAQQKRYQQTKSSA 754

Query: 129 VTLQSQARMWRIRR--------RYCQVLNAVRIIQAYW 158
           + +QS  R W+ R+        + C+   AV  I AYW
Sbjct: 755 LVIQSYIRGWKARKILRELKHQKRCK--EAVTTIAAYW 790


>gi|240120050 myosin IB isoform 1 [Homo sapiens]
          Length = 1136

 Score = 34.3 bits (77), Expect = 0.076
 Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 20/98 (20%)

Query: 69  DTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEAFSRKEWAA 128
           + +AT IQ  +RG   R   L    S  +I  W+          RR A  + + + + +A
Sbjct: 705 EDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWY----------RRYAQQKRYQQTKSSA 754

Query: 129 VTLQSQARMWRIRR--------RYCQVLNAVRIIQAYW 158
           + +QS  R W+ R+        + C+   AV  I AYW
Sbjct: 755 LVIQSYIRGWKARKILRELKHQKRCK--EAVTTIAAYW 790


>gi|21237808 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin c2 isoform b [Homo sapiens]
          Length = 1130

 Score = 34.3 bits (77), Expect = 0.076
 Identities = 36/151 (23%), Positives = 69/151 (45%), Gaps = 20/151 (13%)

Query: 1   MEEKQPQKTKEPSKEDEPQQKEMPTHLSLGAESKAEAKTPVLVETQTVDNANEKSEKPPE 60
           +EE+  +KT E  K+DE + KE  +      ES+     P++          EK ++P E
Sbjct: 813 IEEEAKEKTSEAPKKDEEKGKEGDSE----KESEKSDGDPIV--------DPEKEKEPKE 860

Query: 61  NQKKLSDKDTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEA 120
            Q+++  K+ V ++ +   R T V R +    LS          + +  +K +  AA+E 
Sbjct: 861 GQEEVL-KEVVESEGE---RKTKVERDIGEGNLSTAAAAA----LAAAAVKAKHLAAVEE 912

Query: 121 FSRKEWAAVTLQSQARMWRIRRRYCQVLNAV 151
              K   A+ +++Q +   I+ R+ + L  +
Sbjct: 913 RKIKSLVALLVETQMKKLEIKLRHFEELETI 943


>gi|21237805 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin c2 isoform a [Homo sapiens]
          Length = 1214

 Score = 34.3 bits (77), Expect = 0.076
 Identities = 36/151 (23%), Positives = 69/151 (45%), Gaps = 20/151 (13%)

Query: 1   MEEKQPQKTKEPSKEDEPQQKEMPTHLSLGAESKAEAKTPVLVETQTVDNANEKSEKPPE 60
           +EE+  +KT E  K+DE + KE  +      ES+     P++          EK ++P E
Sbjct: 782 IEEEAKEKTSEAPKKDEEKGKEGDSE----KESEKSDGDPIV--------DPEKEKEPKE 829

Query: 61  NQKKLSDKDTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEA 120
            Q+++  K+ V ++ +   R T V R +    LS          + +  +K +  AA+E 
Sbjct: 830 GQEEVL-KEVVESEGE---RKTKVERDIGEGNLSTAAAAA----LAAAAVKAKHLAAVEE 881

Query: 121 FSRKEWAAVTLQSQARMWRIRRRYCQVLNAV 151
              K   A+ +++Q +   I+ R+ + L  +
Sbjct: 882 RKIKSLVALLVETQMKKLEIKLRHFEELETI 912


>gi|194363725 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin c2 isoform c [Homo sapiens]
          Length = 1152

 Score = 34.3 bits (77), Expect = 0.076
 Identities = 36/151 (23%), Positives = 69/151 (45%), Gaps = 20/151 (13%)

Query: 1   MEEKQPQKTKEPSKEDEPQQKEMPTHLSLGAESKAEAKTPVLVETQTVDNANEKSEKPPE 60
           +EE+  +KT E  K+DE + KE  +      ES+     P++          EK ++P E
Sbjct: 813 IEEEAKEKTSEAPKKDEEKGKEGDSE----KESEKSDGDPIV--------DPEKEKEPKE 860

Query: 61  NQKKLSDKDTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEA 120
            Q+++  K+ V ++ +   R T V R +    LS          + +  +K +  AA+E 
Sbjct: 861 GQEEVL-KEVVESEGE---RKTKVERDIGEGNLSTAAAAA----LAAAAVKAKHLAAVEE 912

Query: 121 FSRKEWAAVTLQSQARMWRIRRRYCQVLNAV 151
              K   A+ +++Q +   I+ R+ + L  +
Sbjct: 913 RKIKSLVALLVETQMKKLEIKLRHFEELETI 943


>gi|217035093 cyclic nucleotide gated channel alpha 1 isoform 1
           [Homo sapiens]
          Length = 759

 Score = 33.9 bits (76), Expect = 0.099
 Identities = 19/69 (27%), Positives = 34/69 (49%), Gaps = 2/69 (2%)

Query: 2   EEKQPQKTKEPSKEDEPQQKEMPTHLSL--GAESKAEAKTPVLVETQTVDNANEKSEKPP 59
           E+     T E S+ + P  +   ++ SL  G  S+ E   P  +    V+N++ K ++P 
Sbjct: 113 EDDDSASTSEESENENPHARGSFSYKSLRKGGPSQREQYLPGAIALFNVNNSSNKDQEPE 172

Query: 60  ENQKKLSDK 68
           E +KK  +K
Sbjct: 173 EKKKKKKEK 181


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.129    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,696,224
Number of Sequences: 37866
Number of extensions: 300494
Number of successful extensions: 2216
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 73
Number of HSP's that attempted gapping in prelim test: 1925
Number of HSP's gapped (non-prelim): 311
length of query: 205
length of database: 18,247,518
effective HSP length: 97
effective length of query: 108
effective length of database: 14,574,516
effective search space: 1574047728
effective search space used: 1574047728
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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