Guide to the Human Genome
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Search of human proteins with 229576894

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|229576894 F-box and WD repeat domain containing 12 isoform 2
[Homo sapiens]
         (394 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|229576894 F-box and WD repeat domain containing 12 isoform 2 ...   816   0.0  
gi|229576873 F-box and WD repeat domain containing 12 isoform 1 ...   746   0.0  
gi|229576906 F-box and WD repeat domain containing 12 isoform 3 ...   692   0.0  
gi|8923179 F-box and leucine-rich repeat protein 12 [Homo sapiens]     41   0.002
gi|27312027 F-box only protein 16 [Homo sapiens]                       40   0.003
gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo ...    39   0.006
gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo ...    39   0.006
gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]     38   0.014
gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens]    37   0.031
gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [H...    36   0.069
gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [H...    36   0.069
gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens]      35   0.090
gi|157743247 F-box protein 45 [Homo sapiens]                           35   0.12 
gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [H...    32   1.00 
gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [H...    32   1.00 
gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2 ...    32   1.3  
gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1 ...    32   1.3  
gi|111185922 F-box protein 36 [Homo sapiens]                           32   1.3  
gi|11545739 F-box and WD repeat domain containing 4 [Homo sapiens]     32   1.3  
gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [H...    31   1.7  
gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [H...    31   1.7  
gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [H...    31   1.7  
gi|24308129 F-box and WD repeat domain containing 5 [Homo sapiens]     31   1.7  
gi|193211598 pleckstrin homology domain containing, family G (wi...    31   2.2  
gi|193211596 pleckstrin homology domain containing, family G (wi...    31   2.2  
gi|193211594 pleckstrin homology domain containing, family G (wi...    31   2.2  
gi|55742734 pleckstrin homology domain containing, family G (wit...    31   2.2  
gi|72198346 B-cell lymphoma protein 2 beta isoform [Homo sapiens]      30   2.9  
gi|72198189 B-cell lymphoma protein 2 alpha isoform [Homo sapiens]     30   2.9  
gi|39812106 tumor differentially expressed protein 1 [Homo sapiens]    30   2.9  

>gi|229576894 F-box and WD repeat domain containing 12 isoform 2
           [Homo sapiens]
          Length = 394

 Score =  816 bits (2109), Expect = 0.0
 Identities = 394/394 (100%), Positives = 394/394 (100%)

Query: 1   MEIRLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHL 60
           MEIRLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHL
Sbjct: 1   MEIRLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHL 60

Query: 61  GTHTWKQFFLHQRRKELRLALAQPHNFIYKVTKNIAFETELAYLSGNRLTVDEQEKSIIC 120
           GTHTWKQFFLHQRRKELRLALAQPHNFIYKVTKNIAFETELAYLSGNRLTVDEQEKSIIC
Sbjct: 61  GTHTWKQFFLHQRRKELRLALAQPHNFIYKVTKNIAFETELAYLSGNRLTVDEQEKSIIC 120

Query: 121 SVSPKQELCAWDVQEVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACG 180
           SVSPKQELCAWDVQEVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACG
Sbjct: 121 SVSPKQELCAWDVQEVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACG 180

Query: 181 TYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTE 240
           TYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTE
Sbjct: 181 TYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTE 240

Query: 241 FITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITG 300
           FITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITG
Sbjct: 241 FITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITG 300

Query: 301 FLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTT 360
           FLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTT
Sbjct: 301 FLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTT 360

Query: 361 DSCISSVMCDNASIVLRVRKVSDSSILVMYSLNT 394
           DSCISSVMCDNASIVLRVRKVSDSSILVMYSLNT
Sbjct: 361 DSCISSVMCDNASIVLRVRKVSDSSILVMYSLNT 394


>gi|229576873 F-box and WD repeat domain containing 12 isoform 1
           [Homo sapiens]
          Length = 464

 Score =  746 bits (1927), Expect = 0.0
 Identities = 382/465 (82%), Positives = 387/465 (83%), Gaps = 72/465 (15%)

Query: 1   MEIRLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHL 60
           MEIRLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHL
Sbjct: 1   MEIRLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHL 60

Query: 61  GTHTWKQFFLHQRRKELRLALAQPHNFIYKVTKNIAFETELAYLSGNRLTVDE------- 113
           GTHTWKQFFLHQRRKELRLALAQPHNFIYKVTKNIAFETELAYLSGNRLTVDE       
Sbjct: 61  GTHTWKQFFLHQRRKELRLALAQPHNFIYKVTKNIAFETELAYLSGNRLTVDEQEKSIIC 120

Query: 114 -------------QEKSIICSVSPKQE-----------------------LCAWDVQE-- 135
                        QE ++I S SP QE                       +  W+ Q+  
Sbjct: 121 SVSPKQELCAWDVQEGTMIWS-SPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRD 179

Query: 136 --------------------------VGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHC 169
                                     VGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHC
Sbjct: 180 ALAVLPMPQPCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHC 239

Query: 170 SPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITL 229
           SPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITL
Sbjct: 240 SPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITL 299

Query: 230 MSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTS 289
           MSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTS
Sbjct: 300 MSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTS 359

Query: 290 GPYLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCC 349
           GPYLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCC
Sbjct: 360 GPYLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCC 419

Query: 350 HLENTWHDHTTDSCISSVMCDNASIVLRVRKVSDSSILVMYSLNT 394
           HLENTWHDHTTDSCISSVMCDNASIVLRVRKVSDSSILVMYSLNT
Sbjct: 420 HLENTWHDHTTDSCISSVMCDNASIVLRVRKVSDSSILVMYSLNT 464


>gi|229576906 F-box and WD repeat domain containing 12 isoform 3
           [Homo sapiens]
          Length = 445

 Score =  692 bits (1787), Expect = 0.0
 Identities = 353/436 (80%), Positives = 358/436 (82%), Gaps = 72/436 (16%)

Query: 30  KHWNRIADSDYLWRSLSLQRWDCSNFTNQHLGTHTWKQFFLHQRRKELRLALAQPHNFIY 89
           KHWNRIADSDYLWRSLSLQRWDCSNFTNQHLGTHTWKQFFLHQRRKELRLALAQPHNFIY
Sbjct: 11  KHWNRIADSDYLWRSLSLQRWDCSNFTNQHLGTHTWKQFFLHQRRKELRLALAQPHNFIY 70

Query: 90  KVTKNIAFETELAYLSGNRLTVDE--------------------QEKSIICSVSPKQE-- 127
           KVTKNIAFETELAYLSGNRLTVDE                    QE ++I S SP QE  
Sbjct: 71  KVTKNIAFETELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEGTMIWS-SPVQEFH 129

Query: 128 ---------------------LCAWDVQE----------------------------VGD 138
                                +  W+ Q+                            VGD
Sbjct: 130 FSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQPCYCMEAYLTKDGPFLMVGD 189

Query: 139 AAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRP 198
           AAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRP
Sbjct: 190 AAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRP 249

Query: 199 SEGSVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQ 258
           SEGSVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQ
Sbjct: 250 SEGSVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQ 309

Query: 259 AYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRFEDHQAAINNFWV 318
           AYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRFEDHQAAINNFWV
Sbjct: 310 AYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRFEDHQAAINNFWV 369

Query: 319 DPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTDSCISSVMCDNASIVLRV 378
           DPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTDSCISSVMCDNASIVLRV
Sbjct: 370 DPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTDSCISSVMCDNASIVLRV 429

Query: 379 RKVSDSSILVMYSLNT 394
           RKVSDSSILVMYSLNT
Sbjct: 430 RKVSDSSILVMYSLNT 445


>gi|8923179 F-box and leucine-rich repeat protein 12 [Homo
          sapiens]
          Length = 326

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 17/45 (37%), Positives = 27/45 (60%)

Query: 3  IRLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSL 47
          + LPD  L  IFS+L +   +++S+V   W R+ D  +LWR + L
Sbjct: 5  VELPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDL 49


>gi|27312027 F-box only protein 16 [Homo sapiens]
          Length = 292

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 26/76 (34%), Positives = 38/76 (50%), Gaps = 1/76 (1%)

Query: 4   RLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHLGTH 63
           +LP +    IFSFLD   L + +QV  HW  +A+ D LW    L+     NF+       
Sbjct: 91  KLPRVLSLYIFSFLDPRSLCRCAQVCWHWKNLAELDQLWMLKCLRFNWYINFSPTPFEQG 150

Query: 64  TWKQFFLHQRRKELRL 79
            WK+ ++ Q  KEL +
Sbjct: 151 IWKKHYI-QMVKELHI 165


>gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo
           sapiens]
          Length = 424

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 22/43 (51%), Positives = 27/43 (62%)

Query: 5   LPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSL 47
           LPD  L  IFS L L  LL+VS V K W R+A  + LW++L L
Sbjct: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDL 142


>gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo
           sapiens]
          Length = 410

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 22/43 (51%), Positives = 27/43 (62%)

Query: 5   LPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSL 47
           LPD  L  IFS L L  LL+VS V K W R+A  + LW++L L
Sbjct: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDL 142


>gi|16306582 F-box and leucine-rich repeat protein 2 [Homo
          sapiens]
          Length = 423

 Score = 38.1 bits (87), Expect = 0.014
 Identities = 18/44 (40%), Positives = 27/44 (61%)

Query: 4  RLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSL 47
          +LP   L RIFSFLD+  L + +Q++K WN +A     W+ + L
Sbjct: 14 KLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDL 57


>gi|27734755 F-box and leucine-rich repeat protein 20 [Homo
          sapiens]
          Length = 436

 Score = 37.0 bits (84), Expect = 0.031
 Identities = 18/44 (40%), Positives = 27/44 (61%)

Query: 4  RLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSL 47
          +LP   L RIFSFLD+  L + +QV++ WN +A     W+ + L
Sbjct: 27 KLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDL 70


>gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [Homo
           sapiens]
          Length = 532

 Score = 35.8 bits (81), Expect = 0.069
 Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 4/76 (5%)

Query: 2   EIRLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHLG 61
           +I+LP      IF +LD   L + +QV+K W  IA+ + LW  L  Q     +  +  + 
Sbjct: 50  DIQLPYELAINIFQYLDRKELGRCAQVSKTWKVIAEDEVLWYRLCQQE---GHLPDSSIS 106

Query: 62  THT-WKQFFLHQRRKE 76
            ++ WK  F   R KE
Sbjct: 107 DYSCWKLIFQECRAKE 122


>gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [Homo
           sapiens]
          Length = 598

 Score = 35.8 bits (81), Expect = 0.069
 Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 4/76 (5%)

Query: 2   EIRLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHLG 61
           +I+LP      IF +LD   L + +QV+K W  IA+ + LW  L  Q     +  +  + 
Sbjct: 116 DIQLPYELAINIFQYLDRKELGRCAQVSKTWKVIAEDEVLWYRLCQQE---GHLPDSSIS 172

Query: 62  THT-WKQFFLHQRRKE 76
            ++ WK  F   R KE
Sbjct: 173 DYSCWKLIFQECRAKE 188


>gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens]
          Length = 491

 Score = 35.4 bits (80), Expect = 0.090
 Identities = 17/44 (38%), Positives = 27/44 (61%)

Query: 4   RLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSL 47
           RLPD ++ +IFSFL    L + ++V + W  +A    LWR++ L
Sbjct: 116 RLPDHSMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRL 159


>gi|157743247 F-box protein 45 [Homo sapiens]
          Length = 286

 Score = 35.0 bits (79), Expect = 0.12
 Identities = 19/45 (42%), Positives = 25/45 (55%), Gaps = 3/45 (6%)

Query: 4  RLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSD---YLWRSL 45
          RLP   L+ +FS+L+L  L   + V KHW R    D    +WRSL
Sbjct: 38 RLPSRVLELVFSYLELSELRSCALVCKHWYRCLHGDENSEVWRSL 82


>gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [Homo
           sapiens]
          Length = 565

 Score = 32.0 bits (71), Expect = 1.00
 Identities = 15/46 (32%), Positives = 25/46 (54%)

Query: 5   LPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRW 50
           LP   +  IFS+L+   L + SQV+  W+++  +  LW+ L    W
Sbjct: 82  LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLYPVHW 127


>gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [Homo
           sapiens]
          Length = 691

 Score = 32.0 bits (71), Expect = 1.00
 Identities = 15/46 (32%), Positives = 25/46 (54%)

Query: 5   LPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRW 50
           LP   +  IFS+L+   L + SQV+  W+++  +  LW+ L    W
Sbjct: 208 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLYPVHW 253


>gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2
           [Homo sapiens]
          Length = 690

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 21/83 (25%), Positives = 36/83 (43%), Gaps = 2/83 (2%)

Query: 5   LPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHLGTHT 64
           LP+ A+ +IF +L L  ++   QVN  W  +   + LW ++        N         T
Sbjct: 158 LPERAILQIFFYLSLKDVIICGQVNHAWMLMTQLNSLWNAIDFS--SVKNVIPDKYIVST 215

Query: 65  WKQFFLHQRRKELRLALAQPHNF 87
            +++ L+  R   R  L +P  F
Sbjct: 216 LQRWRLNVLRLNFRGCLLRPKTF 238


>gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1
           [Homo sapiens]
          Length = 735

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 21/83 (25%), Positives = 36/83 (43%), Gaps = 2/83 (2%)

Query: 5   LPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHLGTHT 64
           LP+ A+ +IF +L L  ++   QVN  W  +   + LW ++        N         T
Sbjct: 158 LPERAILQIFFYLSLKDVIICGQVNHAWMLMTQLNSLWNAIDFS--SVKNVIPDKYIVST 215

Query: 65  WKQFFLHQRRKELRLALAQPHNF 87
            +++ L+  R   R  L +P  F
Sbjct: 216 LQRWRLNVLRLNFRGCLLRPKTF 238


>gi|111185922 F-box protein 36 [Homo sapiens]
          Length = 188

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 4/79 (5%)

Query: 4   RLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHLGTH 63
           RL D  L  I S+LDL  + ++ Q +  + ++  SD LW  +     D      + L   
Sbjct: 96  RLSDDLLLTIISYLDLEDIARLCQTSHRFAKLCMSDKLWEQIVQSTCDTITPDVRALAED 155

Query: 64  T-WKQFFLH---QRRKELR 78
           T W+Q F     Q +++LR
Sbjct: 156 TGWRQLFFTNKLQLQRQLR 174


>gi|11545739 F-box and WD repeat domain containing 4 [Homo
          sapiens]
          Length = 412

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 16/43 (37%), Positives = 25/43 (58%)

Query: 4  RLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLS 46
          RLP+  L  I S+LD+  L +++QV +   R    D LWR ++
Sbjct: 30 RLPEELLLLICSYLDMRALGRLAQVCRWLRRFTSCDLLWRRIA 72


>gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [Homo
           sapiens]
          Length = 589

 Score = 31.2 bits (69), Expect = 1.7
 Identities = 14/39 (35%), Positives = 22/39 (56%)

Query: 5   LPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWR 43
           LP      + SFL+   LLQ +Q  ++W  +A+ + LWR
Sbjct: 166 LPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWR 204


>gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [Homo
           sapiens]
          Length = 707

 Score = 31.2 bits (69), Expect = 1.7
 Identities = 14/39 (35%), Positives = 22/39 (56%)

Query: 5   LPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWR 43
           LP      + SFL+   LLQ +Q  ++W  +A+ + LWR
Sbjct: 284 LPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWR 322


>gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [Homo
           sapiens]
          Length = 627

 Score = 31.2 bits (69), Expect = 1.7
 Identities = 14/39 (35%), Positives = 22/39 (56%)

Query: 5   LPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWR 43
           LP      + SFL+   LLQ +Q  ++W  +A+ + LWR
Sbjct: 204 LPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWR 242


>gi|24308129 F-box and WD repeat domain containing 5 [Homo
          sapiens]
          Length = 566

 Score = 31.2 bits (69), Expect = 1.7
 Identities = 15/65 (23%), Positives = 29/65 (44%)

Query: 5  LPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHLGTHT 64
          LPD  + +IF  L    +L    V + W  ++  ++LWR    + +  +    +H    +
Sbjct: 9  LPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDVPRHPAAMS 68

Query: 65 WKQFF 69
          W + F
Sbjct: 69 WYEEF 73


>gi|193211598 pleckstrin homology domain containing, family G (with
           RhoGef domain) member 4 isoform 1 [Homo sapiens]
          Length = 1191

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 25/90 (27%), Positives = 41/90 (45%), Gaps = 14/90 (15%)

Query: 126 QELCAWDVQEVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRT 185
           Q+LC W++   G A       TLPG RDV      Q   VLL C+    W+ +  +    
Sbjct: 183 QDLC-WELLASGMA-------TLPGTRDV------QGRAVLLLCAHSPAWLQSECSSQEL 228

Query: 186 LPQVFLTESLLRPSEGSVPLSTFLPHKLCA 215
           +  +    S+ RP   ++ L+  +  ++CA
Sbjct: 229 IRLLLYLRSIPRPEVQALGLTVLVDARICA 258


>gi|193211596 pleckstrin homology domain containing, family G (with
           RhoGef domain) member 4 isoform 1 [Homo sapiens]
          Length = 1191

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 25/90 (27%), Positives = 41/90 (45%), Gaps = 14/90 (15%)

Query: 126 QELCAWDVQEVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRT 185
           Q+LC W++   G A       TLPG RDV      Q   VLL C+    W+ +  +    
Sbjct: 183 QDLC-WELLASGMA-------TLPGTRDV------QGRAVLLLCAHSPAWLQSECSSQEL 228

Query: 186 LPQVFLTESLLRPSEGSVPLSTFLPHKLCA 215
           +  +    S+ RP   ++ L+  +  ++CA
Sbjct: 229 IRLLLYLRSIPRPEVQALGLTVLVDARICA 258


>gi|193211594 pleckstrin homology domain containing, family G (with
           RhoGef domain) member 4 isoform 1 [Homo sapiens]
          Length = 1191

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 25/90 (27%), Positives = 41/90 (45%), Gaps = 14/90 (15%)

Query: 126 QELCAWDVQEVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRT 185
           Q+LC W++   G A       TLPG RDV      Q   VLL C+    W+ +  +    
Sbjct: 183 QDLC-WELLASGMA-------TLPGTRDV------QGRAVLLLCAHSPAWLQSECSSQEL 228

Query: 186 LPQVFLTESLLRPSEGSVPLSTFLPHKLCA 215
           +  +    S+ RP   ++ L+  +  ++CA
Sbjct: 229 IRLLLYLRSIPRPEVQALGLTVLVDARICA 258


>gi|55742734 pleckstrin homology domain containing, family G (with
           RhoGef domain) member 4 isoform 1 [Homo sapiens]
          Length = 1191

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 25/90 (27%), Positives = 41/90 (45%), Gaps = 14/90 (15%)

Query: 126 QELCAWDVQEVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRT 185
           Q+LC W++   G A       TLPG RDV      Q   VLL C+    W+ +  +    
Sbjct: 183 QDLC-WELLASGMA-------TLPGTRDV------QGRAVLLLCAHSPAWLQSECSSQEL 228

Query: 186 LPQVFLTESLLRPSEGSVPLSTFLPHKLCA 215
           +  +    S+ RP   ++ L+  +  ++CA
Sbjct: 229 IRLLLYLRSIPRPEVQALGLTVLVDARICA 258


>gi|72198346 B-cell lymphoma protein 2 beta isoform [Homo sapiens]
          Length = 205

 Score = 30.4 bits (67), Expect = 2.9
 Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 11/56 (19%)

Query: 12  RIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHLGTHTWKQ 67
           RI +F +  G++ V  VN+  + + D+  LW          + + N+HL  HTW Q
Sbjct: 146 RIVAFFEFGGVMCVESVNREMSPLVDNIALW---------MTEYLNRHL--HTWIQ 190


>gi|72198189 B-cell lymphoma protein 2 alpha isoform [Homo sapiens]
          Length = 239

 Score = 30.4 bits (67), Expect = 2.9
 Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 11/56 (19%)

Query: 12  RIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHLGTHTWKQ 67
           RI +F +  G++ V  VN+  + + D+  LW          + + N+HL  HTW Q
Sbjct: 146 RIVAFFEFGGVMCVESVNREMSPLVDNIALW---------MTEYLNRHL--HTWIQ 190


>gi|39812106 tumor differentially expressed protein 1 [Homo sapiens]
          Length = 473

 Score = 30.4 bits (67), Expect = 2.9
 Identities = 16/59 (27%), Positives = 30/59 (50%), Gaps = 1/59 (1%)

Query: 260 YEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRFEDHQAAINN-FW 317
           ++I    + A   C + +G    Y I F    +  +FS+  F ++  +D +AA++N FW
Sbjct: 76  FKIHEADINADKDCDVLVGYKAVYRISFAMAIFFFVFSLLMFKVKTSKDLRAAVHNGFW 134


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.135    0.430 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,680,806
Number of Sequences: 37866
Number of extensions: 621770
Number of successful extensions: 1752
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1716
Number of HSP's gapped (non-prelim): 49
length of query: 394
length of database: 18,247,518
effective HSP length: 104
effective length of query: 290
effective length of database: 14,309,454
effective search space: 4149741660
effective search space used: 4149741660
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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